result 1461 件
JaLCDOI | 10.18926/AMO/66670 |
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FullText URL | 78_1_047.pdf |
Author | Shimomura, Manabu| Shinozaki, Katsunori| Yano, Takuya| Akabane, Shintaro| Ohdan, Hideki| Hiroshima Surgical study group of Clinical Oncology (HiSCO)| |
Abstract | Oral fluoropyrimidines (FUs) have certain advantages over intravenous FUs, such as longer intervals between outpatient visits, no requirement for central venous port (CVP) implantation, and lower incidence of neutropenia. We previously reported the efficacy of S-1/oxaliplatin (SOX) with bevacizumab therapy as a first-line treatment for advanced colorectal cancer (CRC) in a prospective phase-II multi-institutional clinical trial (HiSCO-02 study). However, our prognostic data at the time lacked a sufficient observation period. Herein, we analyze the longer-term follow-up data, focusing on the status of eventual CVP implantation via an open-label, non-randomized, multicenter study. This study enrolled 55 patients (mean age, 64 years), of whom 43 died (41 of primary cancer). The median overall survival was 22.7 months (95% CI: 20.1-34.7 months). Post-treatment regimens after failure of first-line treatment were initiated in 43 patients; CPT11-based regimens were selected in most cases, and other oral FU combinations in nine. CVP was implanted in 35 patients prior to first-line treatment; eleven of the remaining 20 patients did not require CVP implantation. In conclusion, we report here the final prognostic update of the Phase II clinical trial examining the efficacy of SOX plus bevacizumab therapy, the results of which confirm the clinical efficacy of this regimen. |
Keywords | metastatic colorectal cancer chemotherapy S-1 prospective phase II study |
Amo Type | Original Article |
Publication Title | Acta Medica Okayama |
Published Date | 2024-02 |
Volume | volume78 |
Issue | issue1 |
Publisher | Okayama University Medical School |
Start Page | 47 |
End Page | 52 |
ISSN | 0386-300X |
NCID | AA00508441 |
Content Type | Journal Article |
language | English |
Copyright Holders | Copyright Ⓒ 2024 by Okayama University Medical School |
File Version | publisher |
Refereed | True |
PubMed ID | 38419314 |
Web of Science KeyUT | 001203658200005 |
FullText URL | fulltext.pdf |
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Author | Tamura, Shuta| Tazawa, Hiroshi| Hori, Naoto| Li, Yuncheng| Yamada, Motohiko| Kikuchi, Satoru| Kuroda, Shinji| Urata, Yasuo| Kagawa, Shunsuke| Fujiwara, Toshiyoshi| |
Published Date | 2023-11-16 |
Publication Title | PLoS ONE |
Volume | volume18 |
Issue | issue11 |
Publisher | Public Library of Science |
Start Page | e0294491 |
ISSN | 1932-6203 |
Content Type | Journal Article |
language | English |
OAI-PMH Set | 岡山大学 |
Copyright Holders | © 2023 Tamura et al. |
File Version | publisher |
PubMed ID | 37972012 |
DOI | 10.1371/journal.pone.0294491 |
Web of Science KeyUT | 001119675000083 |
Related Url | isVersionOf https://doi.org/10.1371/journal.pone.0294491 |
JaLCDOI | 10.18926/66638 |
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FullText URL | oupc_021_031.pdf |
Author | 住岡 恭子| |
Abstract | 本論文では,塚本千秋先生がこれまで相談室紀要に執筆された論文をレビューした。それぞれの論文から,①クライエント・セラピスト双方に流れる時間を意識する重要性,② DV被害者という困難なケースに相対する際に構造を安定させる不断の努力が必要であること,③事例報告において各回のセッションを記述する作業それ自体が臨床研修として有用であること,④助言を行う前にまず目の前のクライエントその人の思いに焦点を当てること,⑤面接の中で思いついた介入を十分吟味すること,⑥試行カウンセリングの臨床現場とは異なる特殊性,⑦精神科医療の動向に,我々心理臨床家が注意を払う必要性,⑧不祥事や倫理的問題を自分ごととして考える重要性,⑨研修における協議が活発になるような架空事例作成の工夫,⑩14回の講義に通底する先生の思想や哲学など,を学ぶことができる。 |
Keywords | 塚本千秋先生 精神医学 臨床心理学 |
Publication Title | Bulletin of the Okayama University Psychological Clinic |
Published Date | 2023-12-25 |
Volume | volume21 |
Start Page | 31 |
End Page | 38 |
ISSN | 2758-6138 |
language | Japanese |
File Version | publisher |
JaLCDOI | 10.18926/66637 |
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FullText URL | oupc_021_025.pdf |
Author | 稲月 聡子| |
Abstract | 本稿では,私立幼稚園における保育心理臨床業務の一つとして行った園内研修の実践について,その概要とアンケート結果を報告する。園内研修の対象者は幼稚園教諭8名で,新版K式発達検査の概要と,園児の発達検査の結果を共有する形で行った。アンケートでは,<発達検査の理解の深まり><子ども理解の深まり><今後の研修の在り方>の3つの大カテゴリーが抽出され,検査を理解することで,結果を通した子ども理解が深まること,クラス担任それぞれが検査結果を通して子ども理解を深めるのみならず,園全体で検査結果を子ども理解に役立てる視点が重要であることが示された。 |
Keywords | 保育心理臨床 園内研修 発達検査 |
Publication Title | Bulletin of the Okayama University Psychological Clinic |
Published Date | 2023-12-25 |
Volume | volume21 |
Start Page | 25 |
End Page | 29 |
ISSN | 2758-6138 |
language | Japanese |
File Version | publisher |
JaLCDOI | 10.18926/66636 |
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FullText URL | oupc_021_015.pdf |
Author | 安藤 美華代| |
Abstract | キャリアのある医療従事者は,多様な課題を抱え職場適応に困難を感じ,職場定着しづらい場合があるものの,組織的な支援については,ほとんど検討されていない。そこで本研究では,キャリアのある新任医療従事者へ心理教育“サクセスフル・セルフ”を活用した研修を行い,本取り組みの意義等について検討することを目的とした。対象は,A 医療機関に採用されたキャリアのある新任職員のうち,本研修会に全回参加した14名である。研修会に関するプロセス評価分析を行った結果,各セッションおよび研修全体における本研修の目標到達度もしくは役立ち度および感想が示され,研修1回目から2回目の質問において同僚の輪にうまく入る,困難に打ち勝つ自己効力感,他者との関係性に関する自己効力感の肯定的変化が見られた。以上より,本研修会の有用性が示唆された。 |
Keywords | 新任医療従事者 こころの健康 心理教育 サクセスフル・セルフ |
Publication Title | Bulletin of the Okayama University Psychological Clinic |
Published Date | 2023-12-25 |
Volume | volume21 |
Start Page | 15 |
End Page | 23 |
ISSN | 2758-6138 |
language | Japanese |
File Version | publisher |
JaLCDOI | 10.18926/66635 |
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FullText URL | oupc_021_007.pdf |
Author | 原 実穂| 東條 光彦| |
Abstract | 貧困や虐待など,子どもを取り巻く危機状況の課題の一つに,「当事者自身が置かれている状況を問題として認識していない」ことが挙げられる。そこで本研究では,児童生徒の危機と,児童生徒の危機への認知能力について教職員がどのように評価しているか調査した。その結果,教職員の視点から「危機や課題を児童生徒自身が認識できている」と判断されるのは半数以下にとどまっていることが明らかとなった(研究Ⅰ)。さらにそれを踏まえ,認知的発達が十分ではないと推測される小学生を対象に,貧困などの「不利益場面」をどの程度認知できるか架空事例を用いて検討したところ,低学年ほど危機について正しい認識ができていないこと,危機察知が低い傾向にある児童は,他者へ援助を求めることの必要性を感じにくいことが示唆された(研究Ⅱ)。 |
Keywords | 心理・社会的危機 援助要請志向性 危機認知 早期発見 架空事例 |
Publication Title | Bulletin of the Okayama University Psychological Clinic |
Published Date | 2023-12-25 |
Volume | volume21 |
Start Page | 7 |
End Page | 13 |
ISSN | 2758-6138 |
language | Japanese |
File Version | publisher |
JaLCDOI | 10.18926/66634 |
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FullText URL | oupc_021_001.pdf |
Author | 塚本 千秋| |
Abstract | よい臨床家とはどのような臨床家だろうか。2023年夏,当大学院の修了生たちに講話を依頼されたので,その機会をとらえて,よい臨床家について考えてみた。考える素材を得るために,最近,関心を集めている生成型人工知能ChatGPTに「よい臨床家とはどのような臨床家か」という問いを投げかけたところ,間違いとはいえないが,とても違和感の強い回答を得た。本稿では,その違和感に焦点を当てながら,筆者の考える“よい臨床家”を紹介したい。 |
Keywords | 臨床家 ChatGPT 臨床家の良し悪し 臨床家の成長 |
Publication Title | Bulletin of the Okayama University Psychological Clinic |
Published Date | 2023-12-25 |
Volume | volume21 |
Start Page | 1 |
End Page | 6 |
ISSN | 2758-6138 |
language | Japanese |
File Version | publisher |
FullText URL | fulltext20240214-01.pdf |
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Author | Miyamoto, Yuichi| |
Keywords | Jugyo kenkyu Jissen kiroku Authorship Voluntary educational research associations Semantic preservation and reconstruction Connoisseurship |
Note | © 2024, Emerald Publishing Limited. This AAM is provided for your own personal use only. It may not be used for resale, reprinting, systematic distribution, emailing, or for any other commercial purpose without the permission of the publisher.| |
Published Date | 2024-02-05 |
Publication Title | International Journal for Lesson and Learning Studies |
Volume | volume13 |
Issue | issue1 |
Publisher | Emerald |
ISSN | 2046-8253 |
Content Type | Journal Article |
language | English |
OAI-PMH Set | 岡山大学 |
Copyright Holders | © 2024, Emerald Publishing Limited |
File Version | author |
DOI | 10.1108/ijlls-05-2023-0062 |
Web of Science KeyUT | 001155604500001 |
Related Url | isVersionOf https://doi.org/10.1108/ijlls-05-2023-0062 |
FullText URL | fulltext.pdf |
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Author | Furuta, Tomoyuki| Yamamoto, Toshio| |
Keywords | genotyping genome comparison next-generation sequencing R package |
Published Date | 2023-12-22 |
Publication Title | DNA Research |
Volume | volume31 |
Issue | issue1 |
Publisher | Oxford University Press |
Start Page | dsad027 |
ISSN | 1340-2838 |
NCID | AA11095219 |
Content Type | Journal Article |
language | English |
OAI-PMH Set | 岡山大学 |
Copyright Holders | © The Author(s) 2023. |
File Version | publisher |
PubMed ID | 38134958 |
DOI | 10.1093/dnares/dsad027 |
Web of Science KeyUT | 001155031000002 |
Related Url | isVersionOf https://doi.org/10.1093/dnares/dsad027 |
FullText URL | fulltext.pdf |
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Author | Sato, Eisuke| Ogita, Sayaka| Mitsudo, Koichi| Suga, Seiji| |
Keywords | N-Alkoxy Amide Cathodic Reduction Weinreb Amide |
Published Date | 2023-11-28 |
Publication Title | Electrochemistry |
Volume | volume91 |
Issue | issue11 |
Publisher | Electrochemical Society of Japan |
Start Page | 112005 |
ISSN | 1344-3542 |
Content Type | Journal Article |
language | English |
OAI-PMH Set | 岡山大学 |
Copyright Holders | © The Author(s) 2023. |
File Version | publisher |
DOI | 10.5796/electrochemistry.23-67079 |
Web of Science KeyUT | 001150553000003 |
Related Url | isVersionOf https://doi.org/10.5796/electrochemistry.23-67079 |
FullText URL | fulltext.pdf |
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Author | Okumura, Yasuyuki| Sato, Eisuke| Mitsudo, Koichi| Suga, Seiji| |
Keywords | Electrosynthesis Benzothiophene S,S-Dioxide Sulfonyl Hydrazide Sulfonyl Radical |
Published Date | 2023-11-28 |
Publication Title | Electrochemistry |
Volume | volume91 |
Issue | issue11 |
Publisher | Electrochemical Society of Japan |
Start Page | 112007 |
ISSN | 1344-3542 |
Content Type | Journal Article |
language | English |
OAI-PMH Set | 岡山大学 |
Copyright Holders | © The Author(s) 2023. |
File Version | publisher |
DOI | 10.5796/electrochemistry.23-67078 |
Web of Science KeyUT | 001150553000002 |
Related Url | isVersionOf https://doi.org/10.5796/electrochemistry.23-67078 |
FullText URL | fulltext.pdf |
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Author | Vo, Quan Duy| Saito, Yukihiro| Nakamura, Kazufumi| Iida, Toshihiro| Yuasa, Shinsuke| |
Keywords | induced pluripotent stem cell ischemic heart disease outcomes safety meta-analysis |
Published Date | 2024-01-12 |
Publication Title | International Journal of Molecular Sciences |
Volume | volume25 |
Issue | issue2 |
Publisher | MDPI |
Start Page | 987 |
ISSN | 1661-6596 |
Content Type | Journal Article |
language | English |
OAI-PMH Set | 岡山大学 |
Copyright Holders | © 2024 by the authors. |
File Version | publisher |
PubMed ID | 38256060 |
DOI | 10.3390/ijms25020987 |
Web of Science KeyUT | 001152823000001 |
Related Url | isVersionOf https://doi.org/10.3390/ijms25020987 |
FullText URL | fulltext.pdf |
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Author | Sakurada, Yasue| Matsuda, Yui| Motohashi, Kanon| Hasegawa, Toru| Otsuka, Yuki| Nakano, Yasuhiro| Tokumasu, Kazuki| Yamamoto, Koichiro| Sunada, Naruhiko| Honda, Hiroyuki| Hagiya, Hideharu| Ueda, Keigo| Otsuka, Fumio| |
Keywords | Depression fatigue menstrual symptoms omicron variant post-COVID-19 condition |
Published Date | 2024-01-25 |
Publication Title | Journal of Psychosomatic Obstetrics & Gynecology |
Volume | volume45 |
Issue | issue1 |
Publisher | Taylor and Francis |
Start Page | 2305899 |
ISSN | 0167-482X |
Content Type | Journal Article |
language | English |
OAI-PMH Set | 岡山大学 |
Copyright Holders | © 2024 The Author(s). |
File Version | publisher |
PubMed ID | 38270210 |
DOI | 10.1080/0167482X.2024.2305899 |
Web of Science KeyUT | 001148717900001 |
Related Url | isVersionOf https://doi.org/10.1080/0167482X.2024.2305899 |
FullText URL | fulltext.pdf |
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Author | Nishimura, Ayumu| Miyoshi, Tomoko| Otsuka, Fumio| Matsukawa, Akihiro| |
Keywords | COVID-19 pandemic Medical students Career path Training hospitals |
Note | The version of record of this article, first published in [Journal name], is available online at Publisher’s website: http://dx.doi.org/10.1186/s12909-023-05021-6| |
Published Date | 2024-01-10 |
Publication Title | BMC Medical Education |
Volume | volume24 |
Issue | issue1 |
Publisher | BMC |
Start Page | 55 |
ISSN | 1472-6920 |
Content Type | Journal Article |
language | English |
OAI-PMH Set | 岡山大学 |
Copyright Holders | © The Author(s) 2024. |
File Version | publisher |
PubMed ID | 38200534 |
DOI | 10.1186/s12909-023-05021-6 |
Web of Science KeyUT | 001140938300007 |
Related Url | isVersionOf https://doi.org/10.1186/s12909-023-05021-6 |
FullText URL | fulltext.pdf |
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Author | Yang, Chen| Shitamukai, Atsunori| Yang, Shucai| Kawaguchi, Ayano| |
Keywords | in vivo electroporation in utero electroporation genome editing IUE iON TEMPO iGONAD |
Published Date | 2023-09-15 |
Publication Title | International Journal of Molecular Sciences |
Volume | volume24 |
Issue | issue18 |
Publisher | MDPI |
Start Page | 14128 |
ISSN | 1661-6596 |
Content Type | Journal Article |
language | English |
OAI-PMH Set | 岡山大学 |
Copyright Holders | © 2023 by the authors. |
File Version | publisher |
PubMed ID | 37762431 |
DOI | 10.3390/ijms241814128 |
Web of Science KeyUT | 001145294000001 |
Related Url | isVersionOf https://doi.org/10.3390/ijms241814128 |
FullText URL | fulltext.pdf |
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Author | Obata, Taisuke| Tsutsumi, Koichiro| Ueta, Eijiro| Oda, Takashi| Kikuchi, Tatsuya| Ako, Soichiro| Fujii, Yuki| Yamazaki, Tatsuhiro| Uchida, Daisuke| Matsumoto, Kazuyuki| Horiguchi, Shigeru| Kato, Hironari| Okada, Hiroyuki| Otsuka, Motoyuki| |
Published Date | 2023-12-12 |
Publication Title | Molecular Therapy Nucleic Acids |
Volume | volume34 |
Publisher | Cell Press |
Start Page | 102054 |
ISSN | 2162-2531 |
Content Type | Journal Article |
language | English |
OAI-PMH Set | 岡山大学 |
Copyright Holders | © 2023 The Author(s). |
File Version | publisher |
PubMed ID | 38111913 |
DOI | 10.1016/j.omtn.2023.102054 |
Web of Science KeyUT | 001146413100001 |
Related Url | isVersionOf https://doi.org/10.1016/j.omtn.2023.102054 |
Title Alternative | The List of Published by Members of the Faculty From January to December 2023. |
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FullText URL | srfa_113_061_073.pdf |
Publication Title | Scientific Reports of the Faculty of Agriculture, Okayama University |
Published Date | 2024-02-01 |
Volume | volume113 |
Start Page | 61 |
End Page | 73 |
ISSN | 2186-7755 |
language | Japanese |
File Version | publisher |
FullText URL | fulltext20240205-01.pdf |
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Author | Tokushige, Keisuke| Abe, Takumi| |
Keywords | C3-N1' bisindoles bromination umpolung rivularin A alkaloid |
Note | This is the peer reviewed version of the following article: [K. Tokushige, T. Abe, Chem. Eur. J. 2024, 30, e202302963. https://doi.org/10.1002/chem.202302963], which has been published in final form at [https://doi.org/10.1002/chem.202302963]. This article may be used for non-commercial purposes in accordance with Wiley Terms and Conditions for Use of Self-Archived Versions. This article may not be enhanced, enriched or otherwise transformed into a derivative work, without express permission from Wiley or by statutory rights under applicable legislation. Copyright notices must not be removed, obscured or modified. The article must be linked to Wiley’s version of record on Wiley Online Library and any embedding, framing or otherwise making available the article or pages thereof by third parties from platforms, services and websites other than Wiley Online Library must be prohibited.| This fulltext file will be available in Jan. 2025.| |
Published Date | 2024-01-08 |
Publication Title | Chemistry – A European Journal |
Volume | volume30 |
Issue | issue11 |
Publisher | Wiley |
Start Page | e202302963 |
ISSN | 0947-6539 |
NCID | AA11076269 |
Content Type | Journal Article |
language | English |
OAI-PMH Set | 岡山大学 |
Copyright Holders | © 2023 Wiley-VCH GmbH |
File Version | author |
PubMed ID | 37988219 |
DOI | 10.1002/chem.202302963 |
Web of Science KeyUT | 001142083100001 |
Related Url | isVersionOf https://doi.org/10.1002/chem.202302963 |
FullText URL | fulltext20240130-01.pdf |
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Author | Miyazaki, Yusuke| Shinoda, Wataru| |
Note | This document is the Accepted Manuscript version of a Published Work that appeared in final form in Journal of Chemical Information and Modeling, copyright © 2023 American Chemical Society after peer review and technical editing by the publisher. To access the final edited and published work see https://doi.org/10.1021/acs.jcim.3c01611.| This fulltext file will be available in Dec. 2024.| |
Published Date | 2023-12-29 |
Publication Title | Journal of Chemical Information and Modeling |
Volume | volume64 |
Issue | issue2 |
Publisher | American Chemical Society (ACS) |
Start Page | 532 |
End Page | 542 |
ISSN | 1549-9596 |
Content Type | Journal Article |
language | English |
OAI-PMH Set | 岡山大学 |
Copyright Holders | © 2023 American Chemical Society |
File Version | author |
PubMed ID | 38156656 |
DOI | 10.1021/acs.jcim.3c01611 |
Web of Science KeyUT | 001146739900001 |
Related Url | isVersionOf https://doi.org/10.1021/acs.jcim.3c01611 |
Author | Suzuki, Shintaro| Barrientos, Tomás| Mejía, Héctor| Price, T. Douglas| |
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Note | © 2023 Elsevier Ltd. This manuscript version is made available under the CC-BY-NC-ND 4.0 license https://creativecommons.org/licenses/by-nc-nd/4.0/| This fulltext file will be available in Dec. 2025.| |
Published Date | 2024-02 |
Publication Title | Journal of Archaeological Science: Reports |
Volume | volume53 |
Publisher | Elsevier BV |
Start Page | 104348 |
ISSN | 2352-409X |
Content Type | Journal Article |
language | English |
OAI-PMH Set | 岡山大学 |
Copyright Holders | © 2023 Elsevier Ltd. |
File Version | author |
DOI | 10.1016/j.jasrep.2023.104348 |
Web of Science KeyUT | 001143409600001 |
Related Url | isVersionOf https://doi.org/10.1016/j.jasrep.2023.104348 |