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Author Yanagisawa, Takafumi| Mori, Keiichiro| Kawada, Tatsushi| Katayama, Satoshi| Tsujino, Takuya| Maenosono, Ryoichi| Toyoda, Shingo| Nukaya, Takuhisa| Morinaka, Hirofumi| Tamura, Keita| Fukuokaya, Wataru| Urabe, Fumihiko| Murakami, Masaya| Bekku, Kensuke| Takahara, Kiyoshi| Fujita, Kazutoshi| Azuma, Haruhito| Araki, Motoo| Inamoto, Teruo| Komura, Kazumasa| Kimura, Takahiro|
Keywords Metastatic renal cell carcinoma Immune checkpoint inhibitor Pembrolizumab Lenvatinib Nivolumab Cabozantinib
Published Date 2026-02-25
Publication Title Cancer Immunology, Immunotherapy
Volume volume75
Issue issue3
Publisher Springer Science and Business Media LLC
Start Page 84
ISSN 1432-0851
Content Type Journal Article
language English
OAI-PMH Set 岡山大学
Copyright Holders © The Author(s) 2026
File Version publisher
PubMed ID 41739193
DOI 10.1007/s00262-025-04288-6
Web of Science KeyUT 001700023300005
Related Url isVersionOf https://doi.org/10.1007/s00262-025-04288-6
JaLCDOI 10.18926/ESR/70297
Title Alternative Large-scale rainfall characteristics at the heavy rainfall event around the western Japan during 5–7 July 2018
FullText URL esr_032_033_044.pdf
Author KATO, Kuranoshin| MATSUMOTO, Kengo| OTANI, Kazuo|
Abstract  Large-scale rainfall characteristics at the heavy rainfall event around the western Japan for 5–7 July 2018 were analyzed with use of the 10-mimute precipitation data at the surface meteorological observation stations of the Japan Meteorological Agency, and so on. In this case, the area with 3 days total precipitation of near or more than 300 mm was distributed widely from northern Kyushu to Shiga and Fukui Prefectures. As in the many heavy rainfall events around Kyushu District in the mature stage of the Baiu season, contribution of the intense rainfall with more than 4 mm/10-minute (24 mm/h) attained about one third of the areal mean total precipitation. However, it is noted that the "not so intense rain" with less than 2 mm/10-minute (12 mm/h) also contributed to about one third of the huge total precipitation in the wide area. In short, this case could be characterized by the mixture of the western Japan type heavy rainfall event and the eastern Japan type one.
Keywords western Japan heavy rainfall in July 2018 10-minute precipitation data east-west difference of the Baiu precipitation
Publication Title Okayama University Earth Science Report
Published Date 2026-03-31
Volume volume32
Issue issue1
Start Page 33
End Page 44
ISSN 1340-7414
language Japanese
Copyright Holders © 2026 by Okayama University Earth Science Reports Editorial Committee All Rights Reserved
File Version publisher
FullText URL fulltext.pdf
Author Fuji, Tomokazu| Takagi, Kosei| Yasui, Kazuya| Ito, Atene| Nishiyama, Takeyoshi| Nagai, Yasuo| Yokoyama, Shohei| Fujiwara, Toshiyoshi|
Keywords Robotic surgery Laparoscopic surgery Limited liver resection Textbook outcome
Published Date 2025-11-27
Publication Title Langenbeck's Archives of Surgery
Volume volume411
Issue issue1
Publisher Springer Science and Business Media LLC
Start Page 22
ISSN 1435-2451
Content Type Journal Article
language English
OAI-PMH Set 岡山大学
Copyright Holders © The Author(s) 2025
File Version publisher
PubMed ID 41307730
DOI 10.1007/s00423-025-03916-0
Web of Science KeyUT 001626981600003
Related Url isVersionOf https://doi.org/10.1007/s00423-025-03916-0
FullText URL fulltext.pdf
Author Toyoda, Shingo| Inoki, Lan| Hashimoto, Mamoru| Fukuokaya, Wataru| Mori, Keiichiro| Nishimura, Shingo| Maenosono, Ryoichi| Iwata, Takehiro| Bekku, Kensuke| Nukaya, Takuhisa| Yanagisawa, Takafumi| Tsujino, Takuya| Komura, Kazumasa| Takahara, Kiyoshi| Inamoto, Teruo| Azuma, Haruhito| Fujita, Kazutoshi| JK-FOOT study group|
Keywords Metastatic renal cell carcinoma Bone metastasis liver metastasis Immuno-oncology
Published Date 2026-01-13
Publication Title Scientific Reports
Volume volume16
Issue issue1
Publisher Springer Science and Business Media LLC
Start Page 3303
ISSN 2045-2322
Content Type Journal Article
language English
OAI-PMH Set 岡山大学
Copyright Holders © The Author(s) 2025
File Version publisher
PubMed ID 41530265
DOI 10.1038/s41598-025-33198-x
Web of Science KeyUT 001684956100001
Related Url isVersionOf https://doi.org/10.1038/s41598-025-33198-x
FullText URL fulltext.pdf
Author Nakayama, Rie| Takaya, Yoichi| Nakashima, Mitsutaka| Nishihara, Takahiro| Toh, Norihisa| Toru, Miyoshi| Nakamura, Kazufumi| Yuasa, Shinsuke|
Keywords Right atrial function Right atrial strain Chronic heart failure Echocardiography
Published Date 2025-11-22
Publication Title BMC Cardiovascular Disorders
Volume volume25
Issue issue1
Publisher Springer Science and Business Media LLC
Start Page 908
ISSN 1471-2261
Content Type Journal Article
language English
OAI-PMH Set 岡山大学
Copyright Holders © The Author(s) 2025.
File Version publisher
PubMed ID 41275105
DOI 10.1186/s12872-025-05307-1
Web of Science KeyUT 001651438800001
Related Url isVersionOf https://doi.org/10.1186/s12872-025-05307-1
JaLCDOI 10.18926/AMO/70075
FullText URL 80_1_069.pdf
Author Wakatsuki, Shinya| Sakamoto, Shinya| Ueno, Akiko| Namba, Takaomi| Yamamoto, Yorito| Matsumoto, Manabu| Iwata, Jun| Okabayashi, Takehiro|
Abstract Patients with hepatocellular carcinoma (HCC) and extensive peritoneal dissemination generally have a poor prognosis and are often resistant to systemic therapy. We report the case of a 47-year-old woman with HCC and massive peritoneal dissemination who presented with malignant ascites requiring repeated cell-free and concentrated ascites reinfusion therapy and peritoneovenous shunt placement, as well as malignant pleural effusion requiring pleurodesis. Combined immunotherapy with durvalumab/tremelimumab was initiated;however, disease progression was observed after three treatment courses, prompting a switch to lenvatinib therapy. Two months after initiation of lenvatinib, CT imaging demonstrated complete disappearance of arterial enhancement in the primary hepatic lesion, along with reduction in the size of peritoneal dissemination nodules. Thirteen months after switching to lenvatinib (16 months after the initial diagnosis), the alpha-fetoprotein level continued to decrease, and the disease remained stable under treatment. Despite the extremely high tumor burden, lenvatinib achieved disease stabilization and symptomatic improvement.
Keywords diagnostic laparoscopy hepatocellular carcinoma peritoneal dissemination lenvatinib
Amo Type Case Report
Publication Title Acta Medica Okayama
Published Date 2026-02
Volume volume80
Issue issue1
Publisher Okayama University Medical School
Start Page 69
End Page 74
ISSN 0386-300X
NCID AA00508441
Content Type Journal Article
language English
Copyright Holders Copyright Ⓒ 2026 by Okayama University Medical School
File Version publisher
Refereed True
PubMed ID 41748152
Web of Science KeyUT 001712986800001
JaLCDOI 10.18926/AMO/70074
FullText URL 80_1_063.pdf
Author Takasu, Eri| Shiode, Yusuke| Kindo, Hiroya| Kimura, Shuhei| Hosokawa, Mio| Matoba, Ryo| Kanzaki, Yuki| Morita, Tetsuro| Adachi, Takuya| Otsuka, Motoyuki| Morizane, Yuki|
Abstract A 77-year-old man undergoing treatment for hepatocellular carcinoma (HCC) presented with blurred vision in his right eye, persisting for 2 months. Slit-lamp microscopy and fundus examination revealed inflammatory cells in the anterior chamber, severe vitreous opacities, and retinal vasculitis in the right eye. The patient underwent vitreous surgery with biopsy, and vitreous cytology confirmed a metastatic intraocular tumor originating from the HCC. Radiotherapy was administered to the right eye, with no recurrence of intraocular inflammation observed at 10 months post-irradiation.
Keywords metastatic intraocular tumor hepatocellular carcinoma panuveitis uveitis masquerade syndrome
Amo Type Case Report
Publication Title Acta Medica Okayama
Published Date 2026-02
Volume volume80
Issue issue1
Publisher Okayama University Medical School
Start Page 63
End Page 67
ISSN 0386-300X
NCID AA00508441
Content Type Journal Article
language English
Copyright Holders Copyright Ⓒ 2026 by Okayama University Medical School
File Version publisher
Refereed True
PubMed ID 41748151
Web of Science KeyUT 001712997700001
JaLCDOI 10.18926/AMO/70072
FullText URL 80_1_047.pdf
Author Eguchi, Yukiomi| Ushio, Soichiro| Irie, Keiichi| Yamashita, Yuta| Eguchi, Miyu| Nakano, Takafumi| Mishima, Kenichi|
Abstract Deregulation of cannabis use is gradually expanding in Europe and the United States. However, the biological processes driving tolerance to delta-9-tetrahydrocannabinol (Δ9-THC), the main psychoactive component of cannabis, remain unclear. Thus, this study aimed to investigate the mechanisms and time course of tolerance development and loss to Δ9-THC in mice. Male ICR mice (7 weeks old) were administered Δ9-THC once daily for 3 days and then divided into three groups according to the washout period (3-, 10-, and 17-day washout groups). After each washout, changes in body temperature and locomotor activity were measured following re-exposure to Δ9-THC. Furthermore, the mRNA expression levels of CB1 and CB2 receptors in the brain were evaluated using real-time PCR. On day 1, significant hypothermia and reduced spontaneous locomotor activity were observed in the Δ9-THC-treated mice compared with the vehicle-treated mice. Tolerance to the hypothermic and locomotor-suppressing effects of Δ9-THC developed on days 2 and 3, respectively, and dissipated after 3 and 11 days of washout, respectively. These differences in the rates of tolerance development and recovery may reflect distinct underlying mechanisms. No significant changes in receptor mRNA expression were observed. These findings highlight the complexity of Δ9-THC tolerance and its potential implications for long-term cannabis use.
Keywords delta-9-tetrahydrocannabinol cannabis tolerance locomotor hypothermic
Amo Type Original Article
Publication Title Acta Medica Okayama
Published Date 2026-02
Volume volume80
Issue issue1
Publisher Okayama University Medical School
Start Page 47
End Page 54
ISSN 0386-300X
NCID AA00508441
Content Type Journal Article
language English
Copyright Holders Copyright Ⓒ 2026 by Okayama University Medical School
File Version publisher
Refereed True
PubMed ID 41748149
Web of Science KeyUT 001712994500006
JaLCDOI 10.18926/AMO/70071
FullText URL 80_1_039.pdf
Author Tezel, Nihal| Can, Aslı Gençay|
Abstract The study aimed to determine the prevalence of kinesiophobia in patients who had undergone lumbar microdiscectomy and to examine its associations with pain intensity, disability, quality of life, depression, anxiety, and satisfaction with surgery. Forty-eight patients with microdiscectomy and 48 healthy controls were enrolled. The Tampa Scale for Kinesiophobia (TSK), Roland-Morris Disability Index (RMDI), Hospital Anxiety and Depression Scale (HADS-A and HADS-D, respectively), and Short Form-36 Health Survey (SF-36) were administered to both groups. The scores of TSK, RMDI, HADS-A, and HADS-D were significantly higher and SF-36 scores were significantly lower in the microdiscectomy than the control group (p<0.001 for all). In the microdiscectomy group, median (min-max) RMDI, HADS-A, and HADS-D scores were 19 (4-34), 10 (0-18), and 9 (0-18), respectively, in kinesiophobic patients, and were significantly higher than 6 (2-20), 3 (0-11), 2.5 (0-11) in non-kinesiophobic patients (all p<0.001). The median (min-max) SF-36 PCS, SF-36 MCS, and VAS scores for surgery satisfaction were 36.5 (8.7-75), 52.1 (11-95), 5, 5 (0-10), respectively, in kinesiophobic patients and were significantly lower than 71 (28-95), 85.5 (9-93), 8.5 (3-10) in non-kinesiophobic patients (all p<0.05). TSK scores were significantly correlated with RMDI, HADS-A, HADS-D, SF-36, and surgery satisfaction scores (all p<0.05). Kinesiophobic patients with lumbar microdiscectomy therefore showed greater disability and psychological morbidity, poorer quality of life, and lower satisfaction with surgery.
Keywords kinesiophobia microdiscectomy disability quality of life depression
Amo Type Original Article
Publication Title Acta Medica Okayama
Published Date 2026-02
Volume volume80
Issue issue1
Publisher Okayama University Medical School
Start Page 39
End Page 46
ISSN 0386-300X
NCID AA00508441
Content Type Journal Article
language English
Copyright Holders Copyright Ⓒ 2026 by Okayama University Medical School
File Version publisher
Refereed True
PubMed ID 41748148
Web of Science KeyUT 001712994500005
JaLCDOI 10.18926/AMO/70070
FullText URL 80_1_031.pdf
Author Ishibashi, Kyota| Oishi, Hirotaka| Araki, Ryo| Kawamura, Kosuke| Sasaki, Isamu| Sasaki, Eiji| Kamada, Hikaru| Kogawa, Masakazu| Tanaka, Sunao| Numasawa, Takuya| Ishibashi, Yasuyuki|
Abstract We investigated global alignment changes following total hip arthroplasty (THA) and predictive alignment parameters for increased cup anteversion (CA) by retrospectively analyzing the primary THA data of 75 patients treated at our hospital (49 women, 26 men; age 65.1±5.7 years, BMI 28.3±3.4 kg/m2). Global alignment parameters, i.e., the anterior pelvic plane angle (APPa) and proximal femoral shaft angle (PFSa) and other alignment parameters were measured. CA was evaluated based on the patients’ standing coronal radiographs. ΔCA was defined as the difference in CA from 2 weeks before to 1 year after each THA. We classified the cases as stable (S) (CA < 10°; n=63) and pelvic retroversion (R) (CA ≥ 10°; n=12) groups. Associations between ΔCA and alignment parameters were evaluated by linear regression and a receiver operating characteristic (ROC) analysis. A significant decrease in the PFSa occurred between the 2-week and 1-year post-THA timepoints (7.8±4.3° vs. 4.2±3.6°, p<0.001), with no notable change in other alignment parameters. At 1-year post-THA, the CA of 12 (16%) patients had increased to 4.5±4.4°. Only the preoperative APPa was positively associated with ΔCA (β=0.165, p=0.020). The ROC analysis revealed that the optimal cut-off value for increased CA in the APPa is 2.1° (area under the curve, 0.700; p=0.020; odds ratio, 4.80). The APPa change predicted increased CA, which emphasizes the importance of the use of preoperative standing radiography for identifying the optimal cup positioning for post-THA changes in CA.
Keywords total hip arthroplasty global alignment anterior pelvic plane cup anteversion pelvic tilt
Amo Type Original Article
Publication Title Acta Medica Okayama
Published Date 2026-02
Volume volume80
Issue issue1
Publisher Okayama University Medical School
Start Page 31
End Page 37
ISSN 0386-300X
NCID AA00508441
Content Type Journal Article
language English
Copyright Holders Copyright Ⓒ 2026 by Okayama University Medical School
File Version publisher
Refereed True
PubMed ID 41748147
Web of Science KeyUT 001712994500004
JaLCDOI 10.18926/AMO/70069
FullText URL 80_1_017.pdf
Author Yano, Hideki| Takahata, Yoko| Yamaguchi, Takeshi| Saito, Shinya|
Abstract This study aimed to develop a scale enabling nurses to objectively evaluate their own stroke discharge support, as a basis for enhancing its overall effectiveness. A draft scale was created based on a literature review, and consisted of a 51-item, 5-point Likert-type questionnaire administered to ward nurses engaged in stroke discharge support at acute care hospitals. Factor analysis was performed to refine the scale. Construct validity was assessed using the known-groups method, and reliability was evaluated through internal consistency analysis. The resulting Stroke Discharge Support Evaluation Scale comprises 29 items across 5 factors, each rated on a 5-point Likert scale. Analysis of the data collected from 237 valid responses demonstrated good internal consistency and supported the scale’s construct validity. The Stroke Discharge Support Evaluation Scale is a reliable and valid tool enabling ward nurses in acute care hospitals to evaluate their own stroke discharge support.
Keywords stroke discharge support scale development
Amo Type Original Article
Publication Title Acta Medica Okayama
Published Date 2026-02
Volume volume80
Issue issue1
Publisher Okayama University Medical School
Start Page 17
End Page 30
ISSN 0386-300X
NCID AA00508441
Content Type Journal Article
language English
Copyright Holders Copyright Ⓒ 2026 by Okayama University Medical School
File Version publisher
Refereed True
PubMed ID 41748146
Web of Science KeyUT 001712994500003
JaLCDOI 10.18926/AMO/70068
FullText URL 80_1_009.pdf
Author Sugahara, Kentaro| Kondo, Takashi| Miyatake, Nobuyuki| Nishi, Hiroyuki| Ujike, Kazuhiro| Koumoto, Kiichi| Namio, Keiichi| Hishii, Shuhei| Katayama, Akihiko| Suzuki, Hiromi| Yamamoto, Yorimasa|
Abstract Appropriate treatments for chronic hemodialysis patients are a public health challenge in Japan. Sedentary behavior appears to be closely associated with these patients’ survival. We thus sought to develop a nomogram that predicts survival based on the duration of chronic hemodialysis patients’ sedentary behavior. One hundred twenty-four patients under chronic hemodialysis (73 men, 51 women, age 71.7±11.1 years) were enrolled in this cohort study. The patients wore a triaxial accelerometer that measured both their sedentary behavior, i.e., total sedentary behavior (minutes) and their maximum sedentary bouts (min) on non-hemodialysis days. We obtained the Kaplan-Meier curve and used the log-rank test and a Cox proportional hazards model to evaluate the relationship between the patients’ sedentary behavior and their survival. We also used a Cox proportional hazards model to develop a nomogram for the patients’ 5-year survival rate. Forty-six patients died during the follow-up period. When we stratified the patients by the medians of total sedentary behavior and maximum sedentary bouts, we observed significant between-group differences. After adjustment for confounding factors in a Cox proportional hazards model, total sedentary behavior and maximum sedentary bouts were identified as critical survival factors, and we generated a nomogram using an index of sedentary behavior. Our analysis results demonstrated that sedentary behavior on non-dialysis days was closely associated with the survival of the chronic hemodialysis patients, suggesting that a decrease in sedentary behavior would prolong their survival. The nomogram developed herein based on sedentary behavior may be useful for predicting the outcomes of chronic hemodialysis patients.
Keywords nomogram chronic hemodialysis sedentary behavior Cox proportional hazards model Kaplan- Meier curve
Amo Type Original Article
Publication Title Acta Medica Okayama
Published Date 2026-02
Volume volume80
Issue issue1
Publisher Okayama University Medical School
Start Page 9
End Page 16
ISSN 0386-300X
NCID AA00508441
Content Type Journal Article
language English
Copyright Holders Copyright Ⓒ 2026 by Okayama University Medical School
File Version publisher
Refereed True
PubMed ID 41748145
Web of Science KeyUT 001712994500002
JaLCDOI 10.18926/AMO/70067
FullText URL 80_1_001.pdf
Author Yamaoka, Hidenaru| Yoshida, Masashi| Sarashina, Toshihiro| Akagi, Satoshi| Miyoshi, Toru| Munemasa, Mitsuru| Nakamura, Kazufumi| Ito, Hiroshi| Yuasa, Shinsuke|
Abstract Venous thromboembolism (VTE) is a serious complication in patients with cancer. In this population, the presence of thrombi is often assessed at cancer diagnosis by measuring D-dimer levels, which have high sensitivity but low specificity for identifying VTE at this clinical time point. However, the usefulness of D-dimer measurement during anticoagulation therapy has not been fully established, despite its widespread use. In this retrospective observational study, we investigated whether D-dimer measurement during anticoagulation therapy in cancer patients could predict overt VTE at follow-up. The study included patients who underwent D-dimer testing and contrast-enhanced computed tomography between 30 and 100 days after initiation of anticoagulation therapy. Eighty-two patients were included: 60 with cancer and 22 without. The diagnostic performance of D-dimer for overt VTE was as follows: sensitivity, 85.7%; specificity, 87.2%; positive predictive value, 78.3%; and negative predictive value, 89.2%. These findings suggest that D-dimer measurement at follow-up has high sensitivity and specificity for overt VTE in cancer patients and may aid in assessing thrombotic status. Clinically, if anticoagulation therapy is continued until D-dimer levels become negative, the absence of overt VTE could be inferred without additional invasive testing.
Keywords D-dimer venous thromboembolism cancer
Amo Type Original Article
Publication Title Acta Medica Okayama
Published Date 2026-02
Volume volume80
Issue issue1
Publisher Okayama University Medical School
Start Page 1
End Page 7
ISSN 0386-300X
NCID AA00508441
Content Type Journal Article
language English
Copyright Holders Copyright Ⓒ 2026 by Okayama University Medical School
File Version publisher
Refereed True
PubMed ID 41748144
Web of Science KeyUT 001712994500001
FullText URL fulltext.pdf
Author Fujiwara, Masaki| Yamada, Yuto| Ishii, Taisuke| Watanabe, Tomone| Fujimori, Maiko| Nakaya, Naoki| Kawamura, Toshihiko| Otsuki, Koji| Shigeyasu, Kunitoshi| Shimazu, Taichi| Hinotsu, Shiro| Uchitomi, Yosuke| Inagaki, Masatoshi|
Keywords colorectal cancer healthcare disparities psycho-oncology schizophrenia spectrum disorders
Published Date 2026-01-14
Publication Title Acta Psychiatrica Scandinavica
Volume volume153
Issue issue3
Publisher Wiley
Start Page 191
End Page 199
ISSN 0001-690X
NCID AA00510057
Content Type Journal Article
language English
OAI-PMH Set 岡山大学
Copyright Holders © 2026 The Author(s).
File Version publisher
PubMed ID 41534847
DOI 10.1111/acps.70065
Web of Science KeyUT 001662914100001
Related Url isVersionOf https://doi.org/10.1111/acps.70065
FullText URL fulltext.pdf
Author Nakajima, Ryo| Azumi, Daisuke| Tada, Masakazu| Nakaichi, Junya| Katsuhara, Koki R.| Nakata, Kazuyoshi|
Keywords agroecosystem conservation ecology endangered amphibian paddy field post-disaster habitat recovery
Published Date 2026-01-23
Publication Title Animals
Volume volume16
Issue issue3
Publisher MDPI AG
Start Page 369
ISSN 2076-2615
Content Type Journal Article
language English
OAI-PMH Set 岡山大学
Copyright Holders © 2026 by the authors.
File Version publisher
DOI 10.3390/ani16030369
Related Url isVersionOf https://doi.org/10.3390/ani16030369
FullText URL fulltext.pdf
Author Harada, Ko| Nishimura, Yoshito| Vu, Quynh Thi| Yamamoto, Maki| Koyama, Toshihiro| Hagiya, Hideharu|
Published Date 2025-06-03
Publication Title ERJ Open Research
Volume volume11
Issue issue6
Publisher European Respiratory Society (ERS)
Start Page 00362-2025
ISSN 2312-0541
Content Type Journal Article
language English
OAI-PMH Set 岡山大学
Copyright Holders ©The authors 2025
File Version publisher
PubMed ID 41333986
DOI 10.1183/23120541.00362-2025
Web of Science KeyUT 001638369600003
Related Url isVersionOf https://doi.org/10.1183/23120541.00362-2025
FullText URL fulltext.pdf
Author Gotoh, Kazuyoshi| Fukushima, Shinnosuke| Hagiya, Hideharu| Tsuji, Shuma| Iio, Koji| Matsushita, Osamu|
Keywords Antimicrobial resistance Invasive meningococcal disease Drug-resistant gene Genome sequence
Published Date 2025-03
Publication Title IJID Regions
Volume volume14
Publisher Elsevier BV
Start Page 100511
ISSN 2772-7076
Content Type Journal Article
language English
OAI-PMH Set 岡山大学
Copyright Holders © 2024 The Author(s).
File Version publisher
PubMed ID 39835185
DOI 10.1016/j.ijregi.2024.100511
Web of Science KeyUT 001410378200001
Related Url isVersionOf https://doi.org/10.1016/j.ijregi.2024.100511
FullText URL fulltext.pdf
Author Ozaki, Y.| Tokuda, E.| Sagara, Y.| Hara, F.| Sasada, S.| Sawaki, M.| Kanbayashi, C.| Yamanaka, T.| Onishi, T.| Fujiki, Y.| Suto, A.| Takahashi, Y.| Tokunaga, E.| Aruga, T.| Nakamura, R.| Fujisawa, T.| Saji, S.| Iwata, H.| Shien, T.|
Keywords breast cancer locoregional recurrence adjuvant chemotherapy inverse probability of treatment weighting
Published Date 2025-11
Publication Title ESMO Open
Volume volume10
Issue issue11
Publisher Elsevier BV
Start Page 105889
ISSN 2059-7029
Content Type Journal Article
language English
OAI-PMH Set 岡山大学
Copyright Holders © 2025 The Author(s).
File Version publisher
PubMed ID 41205354
DOI 10.1016/j.esmoop.2025.105889
Web of Science KeyUT 001617317900002
Related Url isVersionOf https://doi.org/10.1016/j.esmoop.2025.105889
JaLCDOI 10.18926/AMO/69851
FullText URL 79_6_469.pdf
Author Tsujii, Teruyuki| Matsuda, Tatsuo| Kimura, Yuji| Katsube, Ryoichi| Iwadou, Hironori| Funabiki, Sadami| Kamikawa, Yasuaki| Matsuda, Tadakazu|
Abstract We report a rare case of ileus tube-related intussusception in an adult. A 56-year-old man with adhesive bowel obstruction was treated with a nasointestinal ileus tube. Although his condition initially improved, persistent abdominal pain led to the diagnosis of intussusception via CT imaging. Manual repositioning of the tube resolved the intussusception without the need for bowel resection. A review of 80 previously reported cases of ileus tube-associated intussusception (total 81 cases, 95 lesions) highlighted the timing of onset, treatment strategies, and precautions. Early detection and diagnosis are crucial to prevent severe complications and preserve bowel function.
Keywords nasointestinal ileus tube intussusception small bowel obstruction enterectomy conservative treatment
Amo Type Case Report
Publication Title Acta Medica Okayama
Published Date 2025-12
Volume volume79
Issue issue6
Publisher Okayama University Medical School
Start Page 469
End Page 474
ISSN 0386-300X
NCID AA00508441
Content Type Journal Article
language English
Copyright Holders Copyright Ⓒ 2025 by Okayama University Medical School
File Version publisher
Refereed True
PubMed ID 41443810
Web of Science KeyUT 001674277500010
JaLCDOI 10.18926/AMO/69848
FullText URL 79_6_451.pdf
Author Hagihara, Moe| Seike, Keisuke| Hayashino, Kenta| Yasuhara, Takao| Kin, Kyohei| Hirata, Yuichi| Kobayashi, Hiroki| Kitamura, Wataru| Fujiwara, Hideaki| Asada, Noboru| Fujii, Nobuharu| Maeda, Yoshinobu|
Abstract Emicizumab, a bispecific monoclonal antibody, benefits patients with severe hemophilia A. It alters laboratory assessments of coagulation activity, requiring anti-idiotype monoclonal antibodies for accurate monitoring. A 64-year-old man, receiving emicizumab regularly, was admitted for laminoplasty. We planned to use FVIII replacement during the perioperative period after confirming the disappearance of inhibitors, monitoring coagulation activity with anti-idiotype monoclonal antibodies. Activated partial thromboplastin time was prolonged on postoperative day 2, prompting an immediate switch to eptacog alfa. The patient recovered without bleeding. This case underscores the necessity of anti-idiotype monoclonal antibodies for accurate monitoring.
Keywords emicizumab eptacog alfa hemophilia A inhibitor anti-idiotype monoclonal antibodies to emicizumab
Amo Type Case Report
Publication Title Acta Medica Okayama
Published Date 2025-12
Volume volume79
Issue issue6
Publisher Okayama University Medical School
Start Page 451
End Page 455
ISSN 0386-300X
NCID AA00508441
Content Type Journal Article
language English
Copyright Holders Copyright Ⓒ 2025 by Okayama University Medical School
File Version publisher
Refereed True
PubMed ID 41443807
Web of Science KeyUT 001674277500007