result 352 件
| JaLCDOI | 10.18926/AMO/53676 |
|---|---|
| FullText URL | 69_5_301.pdf |
| Author | Seki, Anna| Iwamuro, Masaya| Yoshioka, Masao| Fujii, Nobuharu| Okada, Hiroyuki| Nose, Soichiro| Takata, Katsuyoshi| Yoshino, Tadashi| Yamamoto, Kazuhide| |
| Abstract | A 41-year-old woman was diagnosed with duodenal follicular lymphoma. She had no other lesions and was assigned to a "watch and wait" policy. Swelling of the inguinal lymph nodes appeared 45 months later, and rituximab monotherapy resulted in complete remission. However, follicular lymphoma recurred in the stomach, rectum and mesenteric and external iliac lymph nodes 81 months after the therapy. The patient received rituximab monotherapy again and has remained in complete remission in the fifteenth year after the initial diagnosis. This case suggests the usefulness of rituximab monotherapy in the long-term management of intestinal follicular lymphoma. |
| Keywords | follicular lymphoma duodenum rituximab |
| Amo Type | Case Report |
| Publication Title | Acta Medica Okayama |
| Published Date | 2015-10 |
| Volume | volume69 |
| Issue | issue5 |
| Publisher | Okayama University Medical School |
| Start Page | 301 |
| End Page | 306 |
| ISSN | 0386-300X |
| NCID | AA00508441 |
| Content Type | Journal Article |
| language | English |
| Copyright Holders | CopyrightⒸ 2015 by Okayama University Medical School |
| File Version | publisher |
| Refereed | True |
| PubMed ID | 26490027 |
| Web of Science KeyUT | 000365519600006 |
| JaLCDOI | 10.18926/AMO/53674 |
|---|---|
| FullText URL | 69_5_279.pdf |
| Author | Saito, Yukie| Fujii, Yousuke| Yashiro, Masato| Tsuge, Mitsuru| Nosaka, Nobuyuki| Yamashita, Nobuko| Yamada, Mutsuko| Tsukahara, Hirokazu| Morishima, Tsuneo| |
| Abstract | Lung hyperpermeability affects the development of acute respiratory distress syndrome (ARDS), but therapeutic strategies for the control of microvascular permeability have not been established. We examined the effects of edaravone, dexamethasone, and N-monomethyl-L-arginine (L-NMMA) on permeability changes in human pulmonary microvascular endothelial cells (PMVEC) under a hypercytokinemic state. Human PMVEC were seeded in a Boyden chamber. After monolayer confluence was achieved, the culture media were replaced respectively by culture media containing edaravone, dexamethasone, and L-NMMA. After 24-h incubation, the monolayer was stimulated with tumor necrosis factor-α (TNF-α) and interleukin-1β (IL-1β). Fluorescein-labeled dextran was added. Then the trans-human PMVEC leak was measured. Expressions of vascular endothelial-cadherin (VE-cadherin) and zonula occludens-1 protein (ZO-1) were evaluated using real-time quantitative polymerase chain reaction and immunofluorescence microscopy. The results showed that TNF-α＋IL-1β markedly increased pulmonary microvascular permeability. Pretreatment with edaravone, dexamethasone, or L-NMMA attenuated the hyperpermeability and inhibited the cytokine-induced reduction of VE-cadherin expression on immunofluorescence staining. Edaravone and dexamethasone increased the expression of ZO-1 at both the mRNA and protein levels. Edaravone and dexamethasone inhibited the permeability changes of human PMVEC, at least partly through an enhancement of VE-cadherin. Collectively, these results suggest a potential therapeutic approach for intervention in patients with ARDS. |
| Keywords | pulmonary microvascular endothelial cells permeability edaravone vascular endothelial-cadherin zonula occludens-1 protein |
| Amo Type | Original Article |
| Publication Title | Acta Medica Okayama |
| Published Date | 2015-10 |
| Volume | volume69 |
| Issue | issue5 |
| Publisher | Okayama University Medical School |
| Start Page | 279 |
| End Page | 290 |
| ISSN | 0386-300X |
| NCID | AA00508441 |
| Content Type | Journal Article |
| language | English |
| Copyright Holders | CopyrightⒸ 2015 by Okayama University Medical School |
| File Version | publisher |
| Refereed | True |
| PubMed ID | 26490025 |
| Web of Science KeyUT | 000365519600004 |
| JaLCDOI | 10.18926/AMO/53556 |
|---|---|
| FullText URL | 69_4_205.pdf |
| Author | Okada, Yoshiki| Endo, Hirosuke| Mitani, Shigeru| Fujiwara, Kazuo| Tetsunaga, Tomonori| Kagawa, Yohei| Fujii, Yosuke| Kunisada, Toshiyuki| Ozaki, Toshifumi| |
| Abstract | Total hip arthroplasty (THA) is the most effective treatment for advanced or end-stage hip osteoarthritis. However, venous thromboembolism (VTE) remains one of its unresolved complications. We reviewed the records of 322 patients undergoing primary THA and investigated the efficacy of anticoagulant prophylaxis for VTE. Our study cohort consisted of 60 patients who received no anticoagulants, 100 patients who received a factor Xa inhibitor (fondaparinux), 100 patients who received low molecular weight heparin (enoxaparin), and 62 patients who selectively received no anticoagulant prophylaxis due to perioperative bleeding, weight, and/or hemoglobin concentration. Enhanced 64-slice multidetector row computed tomography was performed postoperatively for 7 days in all cases. The incidence of VTE in the four groups was 15ｵ, 9.0ｵ, 6.0ｵ, and 6.4ｵ, respectively. The incidence of VTE was significantly lower in the groups receiving anticoagulant prophylaxis and the group selectively receiving no anticoagulant prophylaxis than in the group receiving no anticoagulants. Complications of fondaparinux therapy included hepatic dysfunction in 4 cases (4.0ｵ), minor bleeding in 2 cases (2.0ｵ), persistent wound drainage in 3 cases (3.0ｵ), and eruption in 1 case (1.0ｵ). The complications of enoxaparin therapy were persistent wound drainage in 1 case (1.0ｵ) and progression of anemia in 1 case (1.0ｵ). The incidence of VTE was low in patients who selectively received no anticoagulant prophylaxis, so we conclude that anticoagulant prophylaxis should be used selectively in THA cases. |
| Keywords | total hip arthroplasty venous thromboembolism anticoagulant prophylaxis complications |
| Amo Type | Original Article |
| Publication Title | Acta Medica Okayama |
| Published Date | 2015-08 |
| Volume | volume69 |
| Issue | issue4 |
| Publisher | Okayama University Medical School |
| Start Page | 205 |
| End Page | 212 |
| ISSN | 0386-300X |
| NCID | AA00508441 |
| Content Type | Journal Article |
| language | English |
| Copyright Holders | CopyrightⒸ 2015 by Okayama University Medical School |
| File Version | publisher |
| Refereed | True |
| PubMed ID | 26289911 |
| Web of Science KeyUT | 000365519100003 |
| Related Url | http://doi.org/10.18926/AMO/53680 |
| JaLCDOI | 10.18926/OER/53549 |
|---|---|
| Title Alternative | Entrepreneurial Initiatives to the Paradigm Shift towards Sound Material Cycle Economy: A Case Study of Japanese Plastic Food Container Industry |
| FullText URL | oer_047_1_015_030.pdf |
| Author | Fujii, Daiji| |
| Publication Title | 岡山大学経済学会雑誌 |
| Published Date | 2015-07-02 |
| Volume | volume47 |
| Issue | issue1 |
| Start Page | 15 |
| End Page | 30 |
| ISSN | 0386-3069 |
| language | Japanese |
| Copyright Holders | Copyright © 2015 岡山大学経済学会 |
| File Version | publisher |
| NAID | 120005627385 |
| Title Alternative | Successful laparoscopic resection of a cecal tumor in a 95-year-old man |
|---|---|
| FullText URL | 127_117.pdf |
| Author | Watanabe, Ayako| Inada, Ryo| Nagasaka, Takeshi| Yagi, Tomohiko| Matsumoto, Hijiri| Toshima, Toshiaki| Kikuchi, Satoru| Kuroda, Shinshi| Kondo, Yoshitaka| Mori, Yoshiko| Kishimoto, Hiroyuki| Fujiwara, Toshiyoshi| |
| Abstract | We report a successful laparoscopic resection of a cecal tumor in a 95-year-old Japanese man. The patient visited an initial hospital with a complaint of constipation in March 2014. Computed tomography scan and colonoscopy showed a stenotic ileocecal cancer with pericolic lymph node metastases, and he was referred to our department for management. Since his general condition was maintained, we performed a laparoscopic ileocecal resection with regional lymph node dissection for the patient. The operation achieved curative resection, and the tumor was diagnosed as a moderately differentiated adenocarcinoma and graded as pStage IIIa (pT3, pN0, pM0) according to the Japanese Classification of Colorectal Carcinoma, eighth edition. He was discharged on the 11th postoperative day without perioperative complications. Several large-scale randomized controlled trials （RCTs） revealed that laparoscopic surgeries for colorectal cancers have some advantages compared to open surgeries, including superior short-term outcomes and comparable long-term outcomes. Unfortunately, since these RCTs did not include enough elderly patients, the safety and feasibility of laparoscopic surgery for extremely elderly patients are still unknown. With respect to less-invasive procedures, these advantages of laparoscopic surgery are also thought to be the advantages for elderly colorectal cancer patients. |
| Keywords | 超高齢者（extremely elderly patient） 大腸癌（colorectal cancer） 腹腔鏡手術（laparoscopic surgery） |
| Publication Title | 岡山医学会雑誌 |
| Published Date | 2015-08-03 |
| Volume | volume127 |
| Issue | issue2 |
| Start Page | 117 |
| End Page | 121 |
| ISSN | 0030-1558 |
| Related Url | isVersionOf https://doi.org/10.4044/joma.127.117 |
| language | Japanese |
| Copyright Holders | Copyright (c) 2015 岡山医学会 |
| File Version | publisher |
| DOI | 10.4044/joma.127.117 |
| NAID | 130005096253 |
| Author | Fujii, Masataka| |
|---|---|
| Published Date | 2015-03-25 |
| Publication Title | |
| Content Type | Thesis or Dissertation |
| FullText URL | 127_67.pdf |
|---|---|
| Author | 宮阪 英| |
| Publication Title | 岡山医学会雑誌 |
| Published Date | 2015-04-01 |
| Volume | volume127 |
| Issue | issue1 |
| Start Page | 67 |
| End Page | 68 |
| ISSN | 0030-1558 |
| Related Url | http://www.okayama-u.ac.jp/user/oma/ |
| language | Japanese |
| Copyright Holders | Copyright (c) 2015 岡山医学会 |
| File Version | publisher |
| NAID | 120005600986 |
| JaLCDOI | 10.18926/CTED/53244 |
|---|---|
| Title Alternative | Organized and Sustainable Education Program for Drug Abuse Prevention by Yogo-teachers |
| FullText URL | cted_005_139_148.pdf |
| Author | Ueno, Yoshiko| Nishimura, Takae| Hosaka, Sayuri| Yamamoto, Masae| Akasaka, Rie| Arimatu, Ayumi| Fujii, Harue| Yuguchi, Makoto| Torigoe, Kanako| Oonishi, Marika| Nanba, Yumiko| Mori, Ayako| Washida, Hiroe| Nishimoto, Keiko| Hino, Yuko| Matumoto, Tomoko| Ishihara, Tomoko| Todo, Mariko| Yamamoto, Kumiko| Sadamori, Natuki| Yamagami, Nao| Okamoto, Kanako| Matsuo, Hiromi| Kobayashi, Shizuka| Hayashi, Kanako| Mizushima, Nozomi| Sekiyama, Ken-ichi| Fukushima, Takashi| Kamimura, Hiroko| Takahashi, Kayo| |
| Abstract | 学校における喫煙・飲酒・薬物乱用防止教育の充実には，問題行動が顕在化する中学校期だけでなく小学校期 における指導の推進が重要であり，系統的な指導計画を立て，指導者や時間の確保，教材作成などに組織的に取 組み，継続可能なプログラム開発を行う必要がある。そこで，地区内12 校の養護教諭が協働して，発達段階に応 じた系統的・組織的かつ継続可能な地区共通の指導計画を開発し，各校の教育課程・年間計画に位置付けた実践 研究を行った。その結果，指導計画の実施状況は，小学校11 校中，学級活動10 校，ミニ保健指導10 校，長期 休業前指導6 校，広報活動9 校となり，特別支援学校1 校では広報活動のみを行うことができた。小学校におけ る喫煙・飲酒・薬物乱用防止教育の推進には，学校保健活動の中核的役割を担う養護教諭が専門性を活かし協働 して，系統的な指導計画を各校の教育課程に位置付け組織的で継続可能なプログラムとする取組が有効であった。 |
| Keywords | 小学校 健康教育 喫煙・飲酒・薬物乱用防止教育 養護教諭 中核的役割 |
| Publication Title | 岡山大学教師教育開発センター紀要 |
| Published Date | 2015-03-06 |
| Volume | volume5 |
| Start Page | 139 |
| End Page | 148 |
| ISSN | 2186-1323 |
| language | Japanese |
| Copyright Holders | Copyright © 2015 岡山大学教師教育開発センター |
| File Version | publisher |
| NAID | 120005572550 |
| JaLCDOI | 10.18926/OER/53106 |
|---|---|
| Title Alternative | Public Supports to Disaster Restoration and Reconstruction Activities: A Report on Staff Dispatch by Social Welfare Councils from Okayama to Miyagi |
| FullText URL | oer_046_2_233_253.pdf |
| Author | Yoshida, Akira| Fujii, Daiji| |
| Publication Title | 岡山大学経済学会雑誌 |
| Published Date | 2014-12-18 |
| Volume | volume46 |
| Issue | issue2 |
| Start Page | 233 |
| End Page | 253 |
| ISSN | 0386-3069 |
| Related Url | http://www.e.okayama-u.ac.jp/gakkai/ |
| language | Japanese |
| Copyright Holders | Copyright © 2014 岡山大学経済学会 |
| File Version | publisher |
| NAID | 120005540384 |
| Title Alternative | A case of microscopic low-grade appendiceal mucinous neoplasm complicated with appendicitis resected by reduced-port laparoscopic surgery |
|---|---|
| FullText URL | 126_223.pdf |
| Author | Suzuki, Hiromitsu| Kimura, Kouji| Kinoshita, Sigeki| Okano, Kazuo| |
| Abstract | Appendicitis is a benign disease for which surgical treatment is widely provided. The complication of neoplastic lesions may be discovered only after resection. However, in some cases, specimens are not submitted to histopathological examination in Japan because of an extreme deficiency of pathologists. We report our experience with one patient who experienced the complication of latent low-grade appendiceal mucinous neoplasm (LAMN) after surgery for appendicitis. Our patient was an 85-year-old woman. Conservative treatment failed to relieve fever and lower abdominal pain and it was decided to treat her surgically. Abdominal computed tomography (CT) showed appendicitis with severe inflammation and suspected adhesion. We decided to explore the abdominal cavity using a reduced-port laparoscopic approach. We found no mucous debouchment or clear tumors in the specimen. Histopathological findings indicated the coexistence of appendicitis and LAMN. At one year and a half after surgery, there was no evidence of the development of pseudomyxoma peritonei. In appendectomy, it is thought that careful perioperative treatment and a postoperative pathological search are important when there are no preoperative findings suggesting a neoplastic lesion. |
| Keywords | 虫垂炎（appendicitis） 減孔式腹腔鏡手術（reduced-port laparoscopic surgery） 虫垂粘液嚢胞腺腫（low-grade appendiceal mucinous neoplasm (LAMN)） 腹膜偽粘液腫（pseudomyxoma peritonei） 腹腔鏡下虫垂切除術（laparoscopic appendectomy） |
| Publication Title | 岡山医学会雑誌 |
| Published Date | 2014-12-01 |
| Volume | volume126 |
| Issue | issue3 |
| Start Page | 223 |
| End Page | 226 |
| ISSN | 0030-1558 |
| language | Japanese |
| Copyright Holders | Copyright (c) 2014 岡山医学会 |
| File Version | publisher |
| DOI | 10.4044/joma.126.223 |
| NAID | 130004903238 |
| Author | Iwatani, Kayoko| Takata, Katsuyoshi| Sato, Yasuharu| Miyata-Takata, Tomoko| Iwaki, Noriko| Cui, Wei| Sawada-Kitamura, Seiko| Sonobe, Hiroshi| Tamura, Maiko| Saito, Katsuhiko| Miyatani, Katsuya| Yamasaki, Rie| Yamadori, Ichiro| Fujii, Nobuharu| Terasaki, Yasushi| Maeda, Yoshinobu| Tanimoto, Mitsune| Nakamura, Naoya| Yoshino, Tadashi| |
|---|---|
| Published Date | 2014-07 |
| Publication Title | Human Pathology |
| Volume | volume45 |
| Issue | issue7 |
| Content Type | Journal Article |
| Author | Sugiyama, Haruko| Maeda, Yoshinobu| Nishimori, Hisakazu| Yamasuji, Yoshiko| Matsuoka, Ken-ichi| Fujii, Nobuharu| Kondo, Eisei| Shinagawa, Katsuji| Tanaka, Takehiro| Takeuchi, Kengo| Teshima, Takanori| Tanimoto, Mitsune| |
|---|---|
| Published Date | 2014-02 |
| Publication Title | Biology of Blood and Marrow Transplantation |
| Volume | volume20 |
| Issue | issue2 |
| Content Type | Journal Article |
| Author | Sonoi, Norihiro| Soga, Yoshihiko| Maeda, Hiroshi| Ichimura, Koichi| Yoshino, Tadashi| Aoyama, Kazutoshi| Fujii, Nobuharu| Maeda, Yoshinobu| Tanimoto, Mitsune| Logan, Richard| Raber-Durlacher, Judith| Takashiba, Shogo| |
|---|---|
| Published Date | 2012-07 |
| Publication Title | Odontology |
| Volume | volume100 |
| Issue | issue2 |
| Content Type | Journal Article |
| FullText URL | K0004898_abstract_review.pdf K0004898_fulltext.pdf |
|---|---|
| Author | Fujii, Kentaro| |
| Published Date | 2014-03-25 |
| Content Type | Thesis or Dissertation |
| Grant Number | 甲第4898号 |
| Granted Date | 2014-03-25 |
| Thesis Type | Doctor of Philosophy in Medical Science |
| Grantor | 岡山大学 |
| language | Japanese English |
| Author | 平井 成幸| |
|---|---|
| Published Date | 1996-03 |
| Publication Title | 中部日本整形外科災害外科学会雑誌 |
| Volume | volume39 |
| Issue | issue2 |
| Content Type | Journal Article |
| JaLCDOI | 10.18926/OER/52079 |
|---|---|
| FullText URL | oer_045_3_017_031.pdf |
| Author | Fujii, Daiji| |
| Publication Title | 岡山大学経済学会雑誌 |
| Published Date | 2013-12-20 |
| Volume | volume45 |
| Issue | issue3 |
| Start Page | 17 |
| End Page | 31 |
| ISSN | 0386-3069 |
| language | English |
| Copyright Holders | Copyright © 2013 岡山大学経済学会 |
| File Version | publisher |
| NAID | 120005359117 |
| FullText URL | K0004822_abstract_review.pdf K0004822_fulltext.pdf |
|---|---|
| Author | Fujii, Masakuni| |
| Published Date | 2013-09-30 |
| Content Type | Thesis or Dissertation |
| Grant Number | 甲第4822号 |
| Granted Date | 2013-09-30 |
| Thesis Type | Doctor of Philosophy in Medical Science |
| Grantor | 岡山大学 |
| language | Japanese English |
| Author | JARIYATHITIPONG, Paweena| HOSOTANI, Kazuyoshi| FUJII, Takashi| AYANO, Toshiki| |
|---|---|
| Published Date | 2013-08 |
| Publication Title | Proceedings of SCMT3 |
| Content Type | Conference Paper |
| Author | FUJII, Takashi| SAITO, Tadashi| AYANO, Toshiki| |
|---|---|
| Published Date | 2013-08 |
| Publication Title | Proceedings of SCMT3 |
| Content Type | Conference Paper |
| Author | JARIYATHITIPONG, Paweena| HOSOTANI, Kazuyoshi| FUJII, Takashi| AYANO, Toshiki| |
|---|---|
| Published Date | 2013-05 |
| Publication Title | Proceeding of First International Conference on Concrete Sustainability (ICCS13) |
| Content Type | Conference Paper |
