result 370 件
| JaLCDOI | 10.18926/56341 |
|---|---|
| Title Alternative | Toward a J-Form Theory of Knowledge-Creating Firms |
| FullText URL | hss_046_001_011.pdf |
| Author | Fujii, Daiji| |
| Publication Title | Journal of Humanities and Social Sciences |
| Published Date | 2018-11-26 |
| Volume | volume46 |
| Start Page | 1 |
| End Page | 11 |
| ISSN | 1881-1671 |
| language | Japanese |
| Copyright Holders | Copyright (c) 2018 岡山大学大学院社会文化科学研究科 |
| File Version | publisher |
| NAID | 120006540158 |
| JaLCDOI | 10.18926/OER/56317 |
|---|---|
| Title Alternative | Socio-Psychological Impacts of Minoriry in Majoriry: A Preliminary Test |
| FullText URL | oer_050_2_001_010.pdf |
| Author | Moriya, Kakeru| Fujii, Daiji| |
| Publication Title | Okayama Economic Review |
| Published Date | 2018-11-07 |
| Volume | volume50 |
| Issue | issue2 |
| Start Page | 1 |
| End Page | 10 |
| ISSN | 2433-4146 |
| language | Japanese |
| Copyright Holders | Copyright © 2018 岡山大学経済学会 |
| File Version | publisher |
| NAID | 120006534563 |
| FullText URL | K0005642_abstract_review.pdf K0005642_summary.pdf K0005642_fulltext.pdf |
|---|---|
| Author | Fujii, Masayoshi| |
| Published Date | 2017-12-27 |
| Content Type | Thesis or Dissertation |
| Grant Number | 甲第5642号 |
| Granted Date | 2017-12-27 |
| Thesis Type | Doctor of Philosophy in Medical Science |
| Grantor | 岡山大学 |
| language | English |
| JaLCDOI | 10.18926/OER/55677 |
|---|---|
| Title Alternative | Self-Restructuring Process through Utilization of External Organization in Public Sector: A Preliminary Thought |
| FullText URL | oer_049_2_075_081.pdf |
| Author | Fujii, Daiji| |
| Publication Title | Okayama Economic Review |
| Published Date | 2018-02-26 |
| Volume | volume49 |
| Issue | issue2 |
| Start Page | 75 |
| End Page | 81 |
| ISSN | 2433-4146 |
| language | Japanese |
| Copyright Holders | Copyright © 2018 岡山大学経済学会 |
| File Version | publisher |
| NAID | 120006398876 |
| Title Alternative | Alzheimer’s disease : Relationship between the Alzheimer’s disease and human microbiome |
|---|---|
| FullText URL | srfa_107_005_010.pdf |
| Author | Fujii, Yusuke| Morita, Hidetoshi| |
| Abstract | Alzheimer’s disease (AD) is a progressive, neurodegenerative disease characterized by memory and language disorder. The accumulation of senile plaques called β-amyloid and neurofibrillary tangles involving protein tau in the brains of AD patients have been considered as two hallmarks of AD. In AD, it is reported that accumulation of β-amyloid may be observed 25 years before onset, supporting early diagnosis and treatment by brain image analysis, because several techniques have recently been developed to detect β-amyloid and tau protein in brains of persons diagnosed with AD. AD patients are usually suffering from other diseases such as diabetes or periodontal disease, and there is accumulating data to show that these diseases associate with the human microbiome, such as gut and oral microbiota. In this report, the relation ship between AD and the human microbiome is reviewed. |
| Publication Title | Scientific Reports of the Faculty of Agriculture, Okayama University |
| Published Date | 2018-02-01 |
| Volume | volume107 |
| Start Page | 5 |
| End Page | 10 |
| ISSN | 2186-7755 |
| language | Japanese |
| File Version | publisher |
| Title Alternative | The 2016 Incentive Award of the Okayama Medical Association in Cardiovascular and Pulmonary Research (2016 Sunada Prize) |
|---|---|
| FullText URL | 129_155.pdf |
| Author | Fujii, Utako| |
| Publication Title | Journal of Okayama Medical Association |
| Published Date | 2017-12-01 |
| Volume | volume129 |
| Issue | issue3 |
| Start Page | 155 |
| End Page | 157 |
| ISSN | 0030-1558 |
| Related Url | isVersionOf https://doi.org/10.4044/joma.129.155 references https://doi.org/10.1165/rcmb.2016-0015OC |
| language | Japanese |
| Copyright Holders | Copyright (c) 2017 岡山医学会 |
| File Version | publisher |
| DOI | 10.4044/joma.129.155 |
| NAID | 40021393805 |
| JaLCDOI | 10.18926/AMO/55308 |
|---|---|
| FullText URL | 71_4_315.pdf |
| Author | Fujii, Yosuke| Endo, Hirosuke| Mitani, Shigeru| Akazawa, Hirofumi| Tetsunaga, Tomonori| Miyake, Takamasa| Yamada, Kazuki| Aoki, Kiyoshi| Ozaki, Toshifumi| |
| Abstract | We retrospectively reviewed 29 hips in which intertrochanteric osteotomies were performed for severe slipped capital femoral epiphyses. Mean age at surgery: 12.6 years. Mean follow-up period: 6 years. At the final follow-up evaluation, one patient had coxalgia, and six hips showed a limited range of motion. A pistol-grip deformity was observed in 13 hips, osteoarthritis in two hips, and a bump existed in 19 hips on the latest radiographs. Gradual remodeling of the bumps was observed post-operatively in 22 hips. The mean α and β angles and offset α and β improved over time. The remodeling proceeded rapidly for 1 year post-surgery. We compared hips classified as β angles of ≥ 63° to < 63° at the final follow-up evaluation, the mean β angle 1 year post-surgery, and the mean ratio of improvement of the β angle per year from 1 year post-surgery to the final follow up, which differed significantly. Nearly all of the patients who underwent intertrochanteric osteotomies had residual morphologic abnormalities, but few had clinical symptoms. The β angle 1 year post-surgery and the ratio of remodeling of the bump from 1 year post-surgery to the final follow-up can be regarded as a potential predictor of morphologic results after intertrochanteric osteotomy. |
| Keywords | slipped capital femoral epiphyses intertrochanteric osteotomy residual femoral deformity femoroacetabular impingement bone remodeling |
| Amo Type | Original Article |
| Publication Title | Acta Medica Okayama |
| Published Date | 2017-08 |
| Volume | volume71 |
| Issue | issue4 |
| Publisher | Okayama University Medical School |
| Start Page | 315 |
| End Page | 323 |
| ISSN | 0386-300X |
| NCID | AA00508441 |
| Content Type | Journal Article |
| language | English |
| Copyright Holders | CopyrightⒸ 2017 by Okayama University Medical School |
| File Version | publisher |
| Refereed | True |
| PubMed ID | 28824187 |
| JaLCDOI | 10.18926/AMO/55304 |
|---|---|
| FullText URL | 71_4_279.pdf |
| Author | Fujii, Yosuke| Fujiwara, Kazuo| Tetsunaga, Tomonori| Miyake, Takamasa| Yamada, Kazuki| Endo, Hirosuke| Abe, Nobuhiro| Sugita, Naohiko| Mitsuishi, Mamoru| Inoue, Takayuki| Nakashima, Yoshio| Ozaki, Toshifumi| |
| Abstract | We developed a surface matching-type computed tomography (CT)-based navigation system for total hip arthroplasty (the N-navi; TEIJIN NAKASHIMA MEDICAL, Okayama, Japan). In the registration step, surface matching was performed with digitizing points on the pelvic bone surface after coarse paired matching. In the present study, we made model bones from the CT data of patients whose acetabular shapes had various deformities. We measured the distances and angles after surface matching from the fiducial points and evaluated the ability to correct surface-matching registration on each pelvic form, using several areas and numbers of points. When the surface-matching points were taken on the superior area of the acetabulum, the correction was easy for the external direction, but it was difficult to correct for the anterior and proximal directions. The correction was difficult for external and proximal directions on the posterior area. Each area of surface-matching points has particular directions that are easily corrected and other directions that are difficult to correct. The shape of the pelvis also affected the correction ability. Our present findings suggest that checking the position after coarse paired matching and choosing the surface-matching area and points that are optimal to correct will improve the accuracy of total hip arthroplasty and reduce surgical times. |
| Keywords | total hip arthroplasty CT-based navigation system surface matching |
| Amo Type | Original Article |
| Publication Title | Acta Medica Okayama |
| Published Date | 2017-08 |
| Volume | volume71 |
| Issue | issue4 |
| Publisher | Okayama University Medical School |
| Start Page | 279 |
| End Page | 289 |
| ISSN | 0386-300X |
| NCID | AA00508441 |
| Content Type | Journal Article |
| language | English |
| Copyright Holders | CopyrightⒸ 2017 by Okayama University Medical School |
| File Version | publisher |
| Refereed | True |
| PubMed ID | 28824183 |
| FullText URL | K0005573_abstract_review.pdf K0005573_summary.pdf K0005573_fulltext.pdf |
|---|---|
| Author | Fujii, Yosuke| |
| Published Date | 2017-06-30 |
| Content Type | Thesis or Dissertation |
| Grant Number | 甲第5573号 |
| Granted Date | 2017-06-30 |
| Thesis Type | Doctor of Philosophy in Medical Science |
| Grantor | 岡山大学 |
| language | English |
| Copyright Holders | https://creativecommons.org/licenses/by-nc-nd/4.0/deed.ja |
| FullText URL | K0005489 abstract_review.pdf K0005489_summary.pdf K0005489_fulltext.pdf K0005489_other.pdf |
|---|---|
| Author | Fujii, Yukiko| |
| Published Date | 2017-03-24 |
| Content Type | Thesis or Dissertation |
| Grant Number | 甲第5489号 |
| Granted Date | 2017-03-24 |
| Thesis Type | Doctor of Philosophy in Dental Science |
| Grantor | 岡山大学 |
| language | Japanese |
| JaLCDOI | 10.18926/AMO/54987 |
|---|---|
| FullText URL | 71_2_179.pdf |
| Author | Nosaka, Nobuyuki| Tsukahara, Kohei| Knaup, Emily| Yabuuchi, Toshihiko| Kikkawa, Tomonobu| Fujii, Yosuke| Yashiro, Masato| Yasuhara, Takao| Okada, Ayumi| Ugawa, Toyomu| Nakao, Atsunori| Tsukahara, Hirokazu| Date, Isao| |
| Abstract | Newly published clinical practice guidelines recommend intracranial pressure (ICP) monitoring in critical care for the management of pediatric acute encephalopathy (pAE), but the utility of ICP monitoring for pAE has been poorly studied. We recently performed direct ICP monitoring for two patients. We observed that although the direct ICP monitoring had clinical benefits with less body weight gain and no vasopressor use in both cases, this monitoring technique is still invasive. Future studies should determine the utility of non-invasive ICP monitoring systems in pAE to further improve the quality of intensive-care management. |
| Keywords | cerebral perfusion encephalopathy child intracranial pressure neurological intensive care |
| Amo Type | Short Communication |
| Publication Title | Acta Medica Okayama |
| Published Date | 2017-04 |
| Volume | volume71 |
| Issue | issue2 |
| Publisher | Okayama University Medical School |
| Start Page | 179 |
| End Page | 180 |
| ISSN | 0386-300X |
| NCID | AA00508441 |
| Content Type | Journal Article |
| language | English |
| Copyright Holders | CopyrightⒸ 2017 by Okayama University Medical School |
| File Version | publisher |
| Refereed | True |
| PubMed ID | 28420900 |
| Author | Fujii, Utako| |
|---|---|
| Published Date | 2016-12-27 |
| Content Type | Thesis or Dissertation |
| JaLCDOI | 10.18926/OER/54707 |
|---|---|
| Title Alternative | An Interview Transcript on GaN Research History with Dr. Herbert Paul Maruska (2) |
| FullText URL | oer_048_2_055_065.pdf |
| Author | Fujii, Daiji| |
| Publication Title | Okayama Economic Review |
| Published Date | 2016-11-10 |
| Volume | volume48 |
| Issue | issue2 |
| Start Page | 55 |
| End Page | 65 |
| ISSN | 0386-3069 |
| language | Japanese |
| Copyright Holders | Copyright © 2016 岡山大学経済学会 |
| File Version | publisher |
| NAID | 120005898802 |
| Author | Kobashi, Kenta| Ishii, Hiroshi| Nishiyama, Kanako| Matsumi, Yuki| Hatano, Masahide| Fujiwara, Masamitsu| Kurokawa, Tatsuo| Tsunemitsu, Kensuke| |
|---|---|
| Published Date | 2016-12-01 |
| Publication Title | Journal of Okayama Medical Association |
| Volume | volume128 |
| Issue | issue3 |
| Content Type | Journal Article |
| JaLCDOI | 10.18926/OER/54475 |
|---|---|
| Title Alternative | An Interview Transcript on GaN Research History with Dr. Herbert Paul Maruska (1) |
| FullText URL | oer_048_1_061_077.pdf |
| Author | Fujii, Daiji| |
| Publication Title | Okayama Economic Review |
| Published Date | 2016-07-15 |
| Volume | volume48 |
| Issue | issue1 |
| Start Page | 61 |
| End Page | 77 |
| ISSN | 0386-3069 |
| language | Japanese |
| Copyright Holders | Copyright © 2016 岡山大学経済学会 |
| File Version | publisher |
| NAID | 120005822609 |
| FullText URL | K0005252_abstract_review.pdf K0005252_fulltext.pdf K0005252_summary.pdf |
|---|---|
| Author | Fujii, Chikako| |
| Published Date | 2015-12-31 |
| Content Type | Thesis or Dissertation |
| Grant Number | 甲第5252号 |
| Granted Date | 2015-12-31 |
| Thesis Type | Doctor of Philosophy in Medical Science |
| Grantor | 岡山大学 |
| language | English |
| Title Alternative | A primary diffuse large B-cell lymphoma of the liver treated with R-CHOP regimen |
|---|---|
| FullText URL | 127_209.pdf |
| Author | Okada, Hiroshi| Fujii, Soichiro| Watanabe, Kentaro| Shigematu, Terunobu| Miyashita, Katsuhiro| Okazaki, Morihiro| Kobashi, Haruhiko| Yokoyama, Motohiro| Yoshino, Tadashi| |
| Abstract | A 78-year-old Japanese man was referred to our hospital after experiencing black feces. No abnormal finding was detected in the endoscopic examination of his stomach and large intestines. Computed tomography (CT) of the abdomen revealed a tumor lesion in the right lobe of the liver. A needle biopsy of the tumor under ultrasound guidance was performed. A pathological examination of the biopsy specimen showed a diffuse proliferation of lymphoma cells, which was compatible with diffuse large B-cell lymphoma (DLBCL). F-fluorodeoxyglucose (FDG)-positron emission tomography (PET)-CT demonstrated increased FDG uptake only in the liver tumor. We made the diagnosis of primary DLBCL of the liver. After six cycles of rituximab plus cyclophosphamide, doxorubicin, vincristine, and prednisolone (R-CHOP), the patient achieved complete remission and has maintained remission for 2 years since the diagnosis. The R-CHOP regimen might be effective therapy for primary DLBCL of the liver. |
| Keywords | びまん性大細胞型Ｂ細胞リンパ腫（diffuse large B-cell lymphoma） 肝臓（liver） R-CHOP療法（R-CHOP regimen） |
| Publication Title | 岡山医学会雑誌 |
| Published Date | 2015-12-01 |
| Volume | volume127 |
| Issue | issue3 |
| Start Page | 209 |
| End Page | 212 |
| ISSN | 0030-1558 |
| Related Url | isVersionOf https://doi.org/10.4044/joma.127.209 |
| language | Japanese |
| Copyright Holders | Copyright (c) 2015 岡山医学会 |
| File Version | publisher |
| DOI | 10.4044/joma.127.209 |
| NAID | 130005116809 |
| JaLCDOI | 10.18926/AMO/53680 |
|---|---|
| FullText URL | 69_5_325.pdf |
| Author | Okada, Yoshiki| Endo, Hirosuke| Mitani, Shigeru| Fujiwara, Kazuo| Tetsunaga, Tomonori| Kagawa, Yohei| Fujii, Yosuke| Kunisada, Toshiyuki| Ozaki, Toshifumi| |
| Abstract | Total hip arthroplasty (THA) is the most effective treatment for advanced or end-stage hip osteoarthritis. However, venous thromboembolism (VTE) remains one of its unresolved complications. We reviewed the records of 322 patients undergoing primary THA and investigated the efficacy of anticoagulant prophylaxis for VTE. Our study cohort consisted of 60 patients who received no anticoagulants, 100 patients who received a factor Xa inhibitor (fondaparinux), 100 patients who received low molecular weight heparin (enoxaparin), and 62 patients who selectively received no anticoagulant prophylaxis due to perioperative bleeding, weight, and/or hemoglobin concentration. Enhanced 64-slice multidetector row computed tomography was performed postoperatively for 7 days in all cases. The incidence of VTE in the four groups was 15%, 9.0%, 6.0%, and 6.4%, respectively. The incidence of VTE was significantly lower in the groups receiving anticoagulant prophylaxis and the group selectively receiving no anticoagulant prophylaxis than in the group receiving no anticoagulants. Complications of fondaparinux therapy included hepatic dysfunction in 4 cases (4.0%), minor bleeding in 2 cases (2.0%), persistent wound drainage in 3 cases (3.0%), and eruption in 1 case (1.0%). The complications of enoxaparin therapy were persistent wound drainage in 1 case (1.0%) and progression of anemia in 1 case (1.0%). The incidence of VTE was low in patients who selectively received no anticoagulant prophylaxis, so we conclude that anticoagulant prophylaxis should be used selectively in THA cases. |
| Keywords | total hip arthroplasty venous thromboembolism anticoagulant prophylaxis complications |
| Amo Type | Erratum |
| Publication Title | Acta Medica Okayama |
| Published Date | 2015-10 |
| Volume | volume69 |
| Issue | issue5 |
| Publisher | Okayama University Medical School |
| Start Page | 325 |
| End Page | 325 |
| ISSN | 0386-300X |
| NCID | AA00508441 |
| Content Type | Journal Article |
| language | English |
| Copyright Holders | CopyrightⒸ 2015 by Okayama University Medical School |
| File Version | publisher |
| Refereed | True |
| PubMed ID | 26490031 |
| Related Url | http://doi.org/10.18926/AMO/53556 |
| JaLCDOI | 10.18926/AMO/53676 |
|---|---|
| FullText URL | 69_5_301.pdf |
| Author | Seki, Anna| Iwamuro, Masaya| Yoshioka, Masao| Fujii, Nobuharu| Okada, Hiroyuki| Nose, Soichiro| Takata, Katsuyoshi| Yoshino, Tadashi| Yamamoto, Kazuhide| |
| Abstract | A 41-year-old woman was diagnosed with duodenal follicular lymphoma. She had no other lesions and was assigned to a "watch and wait" policy. Swelling of the inguinal lymph nodes appeared 45 months later, and rituximab monotherapy resulted in complete remission. However, follicular lymphoma recurred in the stomach, rectum and mesenteric and external iliac lymph nodes 81 months after the therapy. The patient received rituximab monotherapy again and has remained in complete remission in the fifteenth year after the initial diagnosis. This case suggests the usefulness of rituximab monotherapy in the long-term management of intestinal follicular lymphoma. |
| Keywords | follicular lymphoma duodenum rituximab |
| Amo Type | Case Report |
| Publication Title | Acta Medica Okayama |
| Published Date | 2015-10 |
| Volume | volume69 |
| Issue | issue5 |
| Publisher | Okayama University Medical School |
| Start Page | 301 |
| End Page | 306 |
| ISSN | 0386-300X |
| NCID | AA00508441 |
| Content Type | Journal Article |
| language | English |
| Copyright Holders | CopyrightⒸ 2015 by Okayama University Medical School |
| File Version | publisher |
| Refereed | True |
| PubMed ID | 26490027 |
| Web of Science KeyUT | 000365519600006 |
| JaLCDOI | 10.18926/AMO/53674 |
|---|---|
| FullText URL | 69_5_279.pdf |
| Author | Saito, Yukie| Fujii, Yousuke| Yashiro, Masato| Tsuge, Mitsuru| Nosaka, Nobuyuki| Yamashita, Nobuko| Yamada, Mutsuko| Tsukahara, Hirokazu| Morishima, Tsuneo| |
| Abstract | Lung hyperpermeability affects the development of acute respiratory distress syndrome (ARDS), but therapeutic strategies for the control of microvascular permeability have not been established. We examined the effects of edaravone, dexamethasone, and N-monomethyl-L-arginine (L-NMMA) on permeability changes in human pulmonary microvascular endothelial cells (PMVEC) under a hypercytokinemic state. Human PMVEC were seeded in a Boyden chamber. After monolayer confluence was achieved, the culture media were replaced respectively by culture media containing edaravone, dexamethasone, and L-NMMA. After 24-h incubation, the monolayer was stimulated with tumor necrosis factor-α (TNF-α) and interleukin-1β (IL-1β). Fluorescein-labeled dextran was added. Then the trans-human PMVEC leak was measured. Expressions of vascular endothelial-cadherin (VE-cadherin) and zonula occludens-1 protein (ZO-1) were evaluated using real-time quantitative polymerase chain reaction and immunofluorescence microscopy. The results showed that TNF-α＋IL-1β markedly increased pulmonary microvascular permeability. Pretreatment with edaravone, dexamethasone, or L-NMMA attenuated the hyperpermeability and inhibited the cytokine-induced reduction of VE-cadherin expression on immunofluorescence staining. Edaravone and dexamethasone increased the expression of ZO-1 at both the mRNA and protein levels. Edaravone and dexamethasone inhibited the permeability changes of human PMVEC, at least partly through an enhancement of VE-cadherin. Collectively, these results suggest a potential therapeutic approach for intervention in patients with ARDS. |
| Keywords | pulmonary microvascular endothelial cells permeability edaravone vascular endothelial-cadherin zonula occludens-1 protein |
| Amo Type | Original Article |
| Publication Title | Acta Medica Okayama |
| Published Date | 2015-10 |
| Volume | volume69 |
| Issue | issue5 |
| Publisher | Okayama University Medical School |
| Start Page | 279 |
| End Page | 290 |
| ISSN | 0386-300X |
| NCID | AA00508441 |
| Content Type | Journal Article |
| language | English |
| Copyright Holders | CopyrightⒸ 2015 by Okayama University Medical School |
| File Version | publisher |
| Refereed | True |
| PubMed ID | 26490025 |
| Web of Science KeyUT | 000365519600004 |
