result 267 件
| FullText URL | K0005440_other1.pdf |
|---|---|
| Author | Hiroshi, Umemura| Yamasaki, Osamu| Kaji, Tatsuya| Otsuka, Masaki| Asagoe, Kenji| Takata, Minoru| Iwatsuki, Keiji| |
| Keywords | 5-S-cysteinyl-dopa biomarker lactate dehydrogenase malignant melanoma serum 5-S-CD |
| Note | 学位審査副論文| |
| Published Date | 2017-04 |
| Publication Title | Journal of Dermatology |
| Volume | volume44 |
| Issue | issue4 |
| Publisher | Wiley-Blackwell |
| Start Page | 449 |
| End Page | 454 |
| ISSN | 03852407 |
| NCID | AA00696658 |
| Content Type | Journal Article |
| language | English |
| OAI-PMH Set | 岡山大学 |
| Copyright Holders | https://creativecommons.org/licenses/by-nc-nd/4.0/deed.ja |
| File Version | author |
| PubMed ID | 27786364 |
| DOI | 10.1111/1346-8138.13651 |
| Web of Science KeyUT | 000398690600029 |
| Related Url | isVersionOf https://doi.org/10.1111/1346-8138.13651 |
| FullText URL | Nature_543_7643_131.pdf |
|---|---|
| Author | Suga, Michihiro| Akita, Fusamichi| Sugahara, Michihiro| Kubo, Minoru| Nakajima, Yoshiki| Nakane, Takanori| Yamashita, Keitaro| Umena, Yasufumi| Nakabayashi, Makoto| Yamane, Takahiro| Nakano, Takamitsu| Suzuki, Mamoru| Masuda, Tetsuya| Inoue, Shigeyuki| Kimura, Tetsunari| Nomura, Takashi| Yonekura, Shinichiro| Yu, Long-Jiang| Sakamoto, Tomohiro| Motomura, Taiki| Chen, Jing-Hua| Kato, Yuki| Noguchi, Takumi| Tono, Kensuke| Joti, Yasumasa| Kameshima, Takashi| Hatsui, Takaki| Nango, Eriko| Tanaka, Rie| Naitow, Hisashi| Matsuura, Yoshinori| Yamashita, Ayumi| Yamamoto, Masaki| Nureki, Osamu| Yabashi, Makina| Ishikawa, Tetsuya| Iwata, So| Shen, Jian-Ren| |
| Published Date | 2017-03 |
| Publication Title | Nature |
| Volume | volume543 |
| Issue | issue7643 |
| Publisher | Nature Publishing Group |
| Start Page | 131 |
| End Page | 135 |
| ISSN | 0028-0836 |
| NCID | AA00752384 |
| Content Type | Journal Article |
| language | English |
| OAI-PMH Set | 岡山大学 |
| Copyright Holders | https://creativecommons.org/licenses/by-nc-nd/4.0/deed.ja |
| File Version | author |
| PubMed ID | 28219079 |
| DOI | 10.1038/nature21400 |
| Web of Science KeyUT | 000395671500047 |
| Related Url | https://doi.org/10.1038/nature21400 |
| JaLCDOI | 10.18926/AMO/54807 |
|---|---|
| FullText URL | 70_6_449.pdf |
| Author | Watanabe, Noriyuki| Sugimoto, Yoshihisa| Tanaka, Masato| Mazaki, Tetsuro| Arataki, Shinya| Takigawa, Tomoyuki| Kataoka, Masaki| Kunisada, Toshiyuki| Ozaki, Toshifumi| |
| Abstract | Metastatic epidural spinal cord compression (MESCC) is a common complication in patients with a malignant tumor, but it is difficult to decide the proper time to perform the necessary surgery. Here we analyzed the prognostic factors for postoperative walking ability. We retrospectively reviewed the cases of 112 MESCC patients treated surgically at our institute and divided them into ambulatory (n＝ 88) and non-ambulatory (n＝24) groups based on their American Spinal Injury Association (ASIA) Impairment Scale grades at the final follow-up. We also classified the patients preoperatively using the revised Tokuhashi score. We assessed the correlation between preoperative or intraoperative factors and postoperative walking ability in both groups. Of the 10 patients classified preoperatively as grade A or B, 2 (20 ) were ambulatory at the final follow-up. Of the 102 patients classified preoperatively as grade C, D or E, 86 (84 ) were ambulatory at the final follow-up (p＜0.001). There were no significant differences between the groups in the average total Tokuhashi score. Our analysis revealed that the severity of paralysis significantly affects neurological recovery in patients with MESCC. Patients with MESCC should receive surgery before the preoperative ASIA Impairment Scale grade falls below grade C. |
| Keywords | metastatic epidural spinal cord compression American Spinal Injury Association Impairment Scale Tokuhashi score walking ability prognostic factor |
| Amo Type | Original Article |
| Publication Title | Acta Medica Okayama |
| Published Date | 2016-12 |
| Volume | volume70 |
| Issue | issue6 |
| Publisher | Okayama University Medical School |
| Start Page | 449 |
| End Page | 453 |
| ISSN | 0386-300X |
| NCID | AA00508441 |
| Content Type | Journal Article |
| language | English |
| Copyright Holders | CopyrightⒸ 2016 by Okayama University Medical School |
| File Version | publisher |
| Refereed | True |
| PubMed ID | 28003669 |
| Author | Kobashi, Kenta| Ishii, Hiroshi| Nishiyama, Kanako| Matsumi, Yuki| Hatano, Masahide| Fujiwara, Masamitsu| Kurokawa, Tatsuo| Tsunemitsu, Kensuke| |
|---|---|
| Published Date | 2016-12-01 |
| Publication Title | Journal of Okayama Medical Association |
| Volume | volume128 |
| Issue | issue3 |
| Content Type | Journal Article |
| JaLCDOI | 10.18926/AMO/54510 |
|---|---|
| FullText URL | 70_4_307.pdf |
| Author | Fujiwara, Masaki| Inagaki, Masatoshi| Higuchi, Yuji| Uchitomi, Yosuke| Terada, Seishi| Kodama, Masafumi| Kishi, Yoshiki| Yamada, Norihito| |
| Abstract | Repetitive transcranial magnetic stimulation (rTMS) has been reported to be a new treatment option for treatment-resistant depression. In Japan, there has been limited research into its feasibility, efficacy, and tolerability. We have launched a trial of rTMS for treating medication-resistant major depressive disorder and bipolar depression. We are investigating low-frequency rTMS to the right dorsolateral prefrontal cortex and traditional high-frequency rTMS to the left dorsolateral prefrontal cortex, in 20 patients. The primary outcome of the study is the treatment completion rate. This study will provide new data on the usefulness of rTMS for treatment-resistant depression in Japan. |
| Keywords | repetitive transcranial magnetic stimulation depression treatment resistance low frequency |
| Amo Type | Clinical Study Protocols |
| Publication Title | Acta Medica Okayama |
| Published Date | 2016-08 |
| Volume | volume70 |
| Issue | issue4 |
| Publisher | Okayama University Medical School |
| Start Page | 307 |
| End Page | 311 |
| ISSN | 0386-300X |
| NCID | AA00508441 |
| Content Type | Journal Article |
| language | English |
| Copyright Holders | CopyrightⒸ 2016 by Okayama University Medical School |
| File Version | publisher |
| Refereed | True |
| PubMed ID | 27549679 |
| Web of Science KeyUT | 000384748600014 |
| JaLCDOI | 10.18926/AMO/54501 |
|---|---|
| FullText URL | 70_4_261.pdf |
| Author | Nagata, Kosei| Yamamoto, Shinichi| Miyoshi, Kota| Sato, Masaki| Arino, Yusuke| Mikami, Yoji| |
| Abstract | Eosinophilic granulomatosis with polyangiitis (EGPA, Churg-Strauss syndrome) is a rare systemic vasculitis and is difficult to diagnose. EGPA has a number of symptoms including peripheral dysesthesia caused by mononeuropathy multiplex, which is similar to radiculopathy due to lumbar disc hernia or lumbar spinal stenosis. Therefore, EGPA patients with mononeuropathy multiplex often visit orthopedic clinics, but orthopedic doctors and spine neurosurgeons have limited experience in diagnosing EGPA because of its rarity. We report a consecutive series of patients who were initially diagnosed as having lumbar disc hernia or lumbar spinal stenosis by at least 2 medical institutions from March 2006 to April 2013 but whose final diagnosis was EGPA. All patients had past histories of asthma or eosinophilic pneumonia, and four out of five had peripheral edema. Laboratory data showed abnormally increased eosinophil counts, and nerve conduction studies of all patients revealed axonal damage patterns. All patients recovered from paralysis to a functional level after high-dose steroid treatment. We shortened the duration of diagnosis from 49 days to one day by adopting a diagnostic algorithm after experiencing the first case. |
| Keywords | eosinophilic granulomatosis with polyangiitis mononeuropathy multiplex lumbar disc hernia lumbar spinal stenosis nerve conduction study |
| Amo Type | Case Report |
| Publication Title | Acta Medica Okayama |
| Published Date | 2016-08 |
| Volume | volume70 |
| Issue | issue4 |
| Publisher | Okayama University Medical School |
| Start Page | 261 |
| End Page | 268 |
| ISSN | 0386-300X |
| NCID | AA00508441 |
| Content Type | Journal Article |
| language | English |
| Copyright Holders | CopyrightⒸ 2016 by Okayama University Medical School |
| File Version | publisher |
| Refereed | True |
| PubMed ID | 27549670 |
| Web of Science KeyUT | 000384748600005 |
| FullText URL | K0005325_abstract_review .pdf K0005325_fulltext.pdf |
|---|---|
| Author | Seno, Masaki| |
| Published Date | 2016-03-25 |
| Content Type | Thesis or Dissertation |
| Grant Number | 甲第5325号 |
| Granted Date | 2016-03-25 |
| Thesis Type | Doctor of Philosophy in Dental Science |
| Grantor | 岡山大学 |
| language | Japanese |
| FullText URL | K0005261_abstract_review.pdf K0005261_fulltext.pdf |
|---|---|
| Author | Harada, Masaki| |
| Published Date | 2016-03-25 |
| Content Type | Thesis or Dissertation |
| Grant Number | 甲第5261号 |
| Granted Date | 2016-03-25 |
| Thesis Type | Doctor of Philosophy in Medical Science |
| Grantor | 岡山大学 |
| language | English |
| JaLCDOI | 10.18926/OER/54157 |
|---|---|
| Title Alternative | A Study of Assistance on Supporters of Regional Revitalization and Their Retention: “Local Community Revitalizing Troops” Project and Community Sustainability |
| FullText URL | oer_047_3_001_027.pdf |
| Author | Nakao, Hiroyuki| Hirano, Masaki| |
| Publication Title | 岡山大学経済学会雑誌 |
| Published Date | 2016-03-19 |
| Volume | volume47 |
| Issue | issue3 |
| Start Page | 1 |
| End Page | 27 |
| ISSN | 0386-3069 |
| language | Japanese |
| Copyright Holders | Copyright © 2016 岡山大学経済学会 |
| File Version | publisher |
| NAID | 120005740495 |
| JaLCDOI | 10.18926/OER/54144 |
|---|---|
| Title Alternative | Trends in Okayama Prefectural Finance after the Japanese asset price bubble: A review of financial conditions during the Nagano and Ishii administrations |
| FullText URL | oer_047_2_053_080.pdf |
| Author | Kameyama, Teiji| Hirano, Masaki| |
| Publication Title | 岡山大学経済学会雑誌 |
| Published Date | 2016-02-23 |
| Volume | volume47 |
| Issue | issue2 |
| Start Page | 53 |
| End Page | 80 |
| ISSN | 0386-3069 |
| language | Japanese |
| Copyright Holders | Copyright © 2016 岡山大学経済学会 |
| File Version | publisher |
| NAID | 120005740484 |
| FullText URL | O0004452_abstract_review.pdf O0004452_fulltext.pdf |
|---|---|
| Author | Otsuka, Masaki| |
| Published Date | 2015-12-31 |
| Content Type | Thesis or Dissertation |
| Grant Number | 乙第4452号 |
| Granted Date | 2015-12-31 |
| Thesis Type | Doctor of Philosophy in Medical Science |
| Grantor | 岡山大学 |
| language | English |
| FullText URL | yamaoka_APSIPA2015_rev9.pdf |
|---|---|
| Author | Yamaoka, Masaki| Hara, Sunao| Abe, Masanobu| |
| Published Date | 2015-12 |
| Publication Title | Proceedings of APSIPA Annual Summit and Conference 2015 |
| Start Page | 223 |
| End Page | 226 |
| Content Type | Conference Paper |
| language | English |
| OAI-PMH Set | 岡山大学 |
| Copyright Holders | ©2015 APSIPA |
| File Version | author |
| Official Url | http://www.apsipa2015.org/| |
| Related Url | http://www.apsipa.org/proceedings_2015/pdf/74.pdf |
| Author | Yoshimura, Teizo| Howard, O. M. Zack| Ito, Toshihiro| Kuwabara, Masaki| Matsukawa, Akihiro| Chen, Keqiang| Liu, Ying| Liu, Mingyong| Oppenheim, Joost J.| Wang, Ji Ming| |
|---|---|
| Published Date | 2013-03-18 |
| Publication Title | PLOS ONE |
| Volume | volume8 |
| Issue | issue3 |
| Content Type | Journal Article |
| FullText URL | Nature-Shen manuscript for deposit(151002).pdf |
|---|---|
| Author | Suga, Michihiro| Akita, Fusamichi| Hirata, Kunio| Ueno, Go| Murakami, Hironori| Nakajima, Yoshiki| Shimizu, Tetsuya| Yamashita, Keitaro| Yamamoto, Masaki| Ago, Hideo| Shen, Jian-Ren| |
| Note | The final publication is available at Nature via http://dx.doi.org/10.1038/nature13991| |
| Published Date | 2015-01-01 |
| Publication Title | Nature |
| Volume | volume517 |
| Publisher | Nature Publishing Group |
| Start Page | 99 |
| End Page | 103 |
| ISSN | 0028-0836 |
| NCID | AA00752384 |
| Content Type | Journal Article |
| language | English |
| OAI-PMH Set | 岡山大学 |
| Copyright Holders | © 2015 Michihiro Suga et al.; licensee Macmillan Publishers Limited. |
| File Version | author |
| PubMed ID | 25470056 |
| DOI | 10.1038/nature13991 |
| Web of Science KeyUT | 000347178400043 |
| Author | Tada, Kotaro| Hamada, Toshihisa| Asagoe, Kenji| Umemura, Hiroshi| Mizuno-Ikeda, Kazuko| Aoyama, Yumi| Otsuka, Masaki| Yamasaki, Osamu| Iwatsuki, Keiji| |
|---|---|
| Published Date | 2014-11 |
| Publication Title | European Journal of Dermatology |
| Volume | volume24 |
| Issue | issue6 |
| Content Type | Journal Article |
| JaLCDOI | 10.18926/AMO/53118 |
|---|---|
| FullText URL | 69_1_17.pdf |
| Author | Suzuki, Norihiro| Takata, Minoru| Shirafuji, Yoshinori| Otsuka, Masaki| Yamasaki, Osamu| Asagoe, Kenji| Hatta, Naohito| Iwatsuki, Keiji| |
| Abstract | Sentinel lymph node (SLN) biopsies have widely been used for the detection of occult LN metastasis of malignant melanoma (MM). In addition to conventional biomarkers, we assessed the diagnostic and prognostic significance of melanoma-initiating cell (MIC) markers in SLNs of MM. We examined the expressions of gp100, MART-1 and tyrosinase mRNA for routine diagnosis and those of ABCB5, CD133, nestin, KDM5B, NGFR and RANK mRNA as MIC markers. The presence of micrometastasis was confirmed immunohistochemically using antibodies to S-100, HMB-45, MART-1, and tyrosinase. Discordance between immunohistochemical and molecular data was observed in 14 of 70 (20.0%) patients, among whom five (7.1%) were positive for only molecular markers;two of these five patients tested positive for micrometastasis by repeated immunohistochemical stainings. The quantitative expression levels of gp100, MART-1, and tyrosinase mRNA were significantly higher in the metastatic LNs;the cut-off values remain to be elucidated. ABCB5 mRNA expression was detected more frequently in the metastatic SLNs (p＜0.05) and in the group of patients with recurrence. To make a definite diagnosis of metastasis, we still need a combination of immunohistochemical and molecular probes. ABCB5 might be a suitable molecular marker for the detection of melanoma-initiating cells in SLNs. |
| Keywords | melanoma cancer-initiating cell sentinel lymph node ABCB5 |
| Amo Type | Original Article |
| Publication Title | Acta Medica Okayama |
| Published Date | 2015-02 |
| Volume | volume69 |
| Issue | issue1 |
| Publisher | Okayama University Medical School |
| Start Page | 17 |
| End Page | 27 |
| ISSN | 0386-300X |
| NCID | AA00508441 |
| Content Type | Journal Article |
| language | English |
| Copyright Holders | CopyrightⒸ 2015 by Okayama University Medical School |
| File Version | publisher |
| Refereed | True |
| PubMed ID | 25703167 |
| Web of Science KeyUT | 000349740300002 |
| Related Url | http://ousar.lib.okayama-u.ac.jp/metadata/53114 |
| Author | Nakayama, Kazunori| Nakao, Kazushi| Takatori, Yuji| Inoue, Junko| Kojo, Shoichirou| Akagi, Shigeru| Fukushima, Masaki| Wada, Jun| Makino, Hirofumi| |
|---|---|
| Published Date | 2013-12-18 |
| Publication Title | International Journal of Nephrology and Renovascular Disease |
| Volume | volume7 |
| Content Type | Journal Article |
| JaLCDOI | 10.18926/OER/51693 |
|---|---|
| Title Alternative | A Study on the Expiration of the Calculation upon Mergers of Local Tax Allocation - Do Intergovernmental Fiscal Relations Keep Working? - |
| FullText URL | oer_045_2_059_085.pdf |
| Author | Ota, Yuji| Hirao, Masaki| |
| Publication Title | 岡山大学経済学会雑誌 |
| Published Date | 2013-09-20 |
| Volume | volume45 |
| Issue | issue2 |
| Start Page | 59 |
| End Page | 85 |
| ISSN | 0386-3069 |
| language | Japanese |
| Copyright Holders | Copyright © 2013 岡山大学経済学会 |
| File Version | publisher |
| NAID | 120005326907 |
| Author | Masaki, Asuka| |
|---|---|
| Published Date | 2013-03-25 |
| Publication Title | |
| Content Type | Thesis or Dissertation |
| JaLCDOI | 10.18926/AMO/49040 |
|---|---|
| FullText URL | 66_6_443.pdf |
| Author | Ugawa, Toyomu| Sakurama, Kazufumi| Yorifuji, Takashi| Takaoka, Munenori| Fujiwara, Yasuhiro| Kabashima, Narutoshi| Azuma, Daisuke| Hirayama, Takahiro| Tsukahara, Kohei| Morisada, Sunao| Iida, Atsuyoshi| Tada, Keitaro| Shiba, Naoki| Sato, Nobuo| Ichiba, Shingo| Kino, Koichi| Fukushima, Masaki| Ujike, Yoshihito| |
| Abstract | The functioning of an arteriovenous fistula (AVF) used for vascular access during hemodialysis has been assessed mainly by dilution methods. Although these techniques indicate the immediate recirculation rate, the results obtained may not correlate with Kt/V. In contrast, the clearance gap (CL-Gap) method provides the total recirculation rate per dialysis session and correlates well with Kt/V. We assessed the correlation between Kt/V and CL-Gap as well as the change in radial artery (RA) blood flow speed in the fistula before percutaneous transluminal angioplasty (PTA) in 45 patients undergoing continuous hemodialysis. The dialysis dose during the determination of CL-Gap was 1.2 to 1.4 Kt/V. Patients with a 10% elevation or more than a 10% relative increase in CL-Gap underwent PTA (n＝45), and the values obtained for Kt/V and CL-Gap before PTA were compared with those obtained immediately afterward. The mean RA blood flow speed improved significantly (from 52.9 to 97.5cm/sec) after PTA, as did Kt/V (1.07 to 1.30) and CL-Gap (14.1% to －0.2%). A significant correlation between these differences was apparent (r＝－0.436 and p＝0.003). These findings suggest that calculating CL-Gap may be useful for determining when PTA is required and for assessing the effectiveness of PTA, toward obtaining better dialysis. |
| Keywords | hemodialysis recirculation clearance gap vascular access percutaneous transluminal angioplasty |
| Amo Type | Original Article |
| Publication Title | Acta Medica Okayama |
| Published Date | 2012-12 |
| Volume | volume66 |
| Issue | issue6 |
| Publisher | Okayama University Medical School |
| Start Page | 443 |
| End Page | 447 |
| ISSN | 0386-300X |
| NCID | AA00508441 |
| Content Type | Journal Article |
| language | English |
| Copyright Holders | CopyrightⒸ 2012 by Okayama University Medical School |
| File Version | publisher |
| Refereed | True |
| PubMed ID | 23254578 |
| Web of Science KeyUT | 000312966100003 |
