result 5801 件
Author | Hasei, Joe| Sasaki, Tsuyoshi| Tazawa, Hiroshi| Osaki, Shuhei| Yamakawa, Yasuaki| Kunisada, Toshiyuki| Yoshida, Aki| Hashimoto, Yuuri| Onishi, Teppei| Uno, Futoshi| Kagawa, Shunsuke| Urata, Yasuo| Ozaki, Toshifumi| Fujiwara, Toshiyoshi| |
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Published Date | 2013-03 |
Publication Title | Molecular Cancer Therapeutics |
Volume | volume12 |
Issue | issue3 |
Content Type | Journal Article |
Author | Nishikawa, Toshio| Takaoka, Munenori| Ohara, Toshiaki| Tomono, Yasuko| Hao, Huifang| Bao, Xiaohong| Fukazawa, Takuya| Wang, Zhigang| Sakurama, Kazufumi| Fujiwara, Yasuhiro| Motoki, Takayuki| Shirakawa, Yasuhiro| Yamatsuji, Tomoki| Tanaka, Noriaki| Fujiwara, Toshiyoshi| Naomoto, Yoshio| |
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Published Date | 2013-03 |
Publication Title | Cancer Biology & Therapy |
Volume | volume14 |
Issue | issue3 |
Content Type | Journal Article |
Author | Obika, Masanari| Ogawa, Hiroko| Takahashi, Katsuyuki| Li, Jiayi| Hatipoglu, Omer Faruk| Cilek, Mehmet Zeynel| Miyoshi, Toru| Inagaki, Junko| Ohtsuki, Takashi| Kusachi, Shozo| Ninomiya, Yoshifumi| Hirohata, Satoshi| |
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Published Date | 2012-10 |
Publication Title | Cancer Science |
Volume | volume103 |
Issue | issue10 |
Content Type | Journal Article |
Author | Yamasaki, Yoshiki| Konno, Haruyoshi| |
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Published Date | 1987-03 |
Publication Title | 農学研究 |
Volume | volume61 |
Issue | issue3 |
Content Type | Departmental Bulletin Paper |
Author | Furumatsu, Takayuki| Matsumoto, Emi| Kanazawa, Tomoko| Fujii, Masataka| Lu, Zhichao| Kajiki, Ryotaro| Ozaki, Toshifumi| |
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Published Date | 2013-05-31 |
Publication Title | Journal of Biomechanics |
Volume | volume46 |
Issue | issue9 |
Content Type | Journal Article |
JaLCDOI | 10.18926/AMO/51066 |
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FullText URL | 67_4_219.pdf |
Author | Maruyama, Hidehiko| Nakamura, Makoto| Yonemoto, Naohiro| Kageyama, Misao| |
Abstract | Cholestasis and thrombocytopenia are complications that affect infants born small for gestational age (SGA). In SGA infants, other vital organs develop at the expense of the liver, and the thrombopoietin produced by the liver is low, often resulting in cholestasis. We hypothesized that thrombocytopenia at birth can be used to predict cholestasis in very-low-birth-weight infants (VLBWIs) with SGA. This retrospective cohort study enrolled VLBWIs with SGA admitted to a tertiary neonatal intensive care unit. A platelet cutoff value predictive of cholestasis was determined using receiver operating characteristic analysis. Multivariate logistic regression analysis was performed to evaluate the platelet cutoff value, and adjusted odds ratios (ORs) and 95% confidence intervals (CIs) were calculated. Regarding the onset of cholestasis, survival analysis was performed by calculating the adjusted hazard ratios (HRs) and 95% CIs. A total of 87 infants were evaluated, and the platelet cutoff value was determined as 88×10(3) cells/μl. The adjusted OR for this platelet cutoff value was 10.52 (95% CI 2.26-55.93, p=0.003), and the adjusted HR was 7.76 (95% CI 2.51-23.50, p=0.0006). Thrombocytopenia is a useful predictor for cholestasis in VLBWIs with SGA. |
Keywords | cholestasis platelet small for gestational age thrombocytopenia very low birth weight |
Amo Type | Original Article |
Publication Title | Acta Medica Okayama |
Published Date | 2013-08 |
Volume | volume67 |
Issue | issue4 |
Publisher | Okayama University Medical School |
Start Page | 219 |
End Page | 225 |
ISSN | 0386-300X |
NCID | AA00508441 |
Content Type | Journal Article |
language | English |
Copyright Holders | CopyrightⒸ 2013 by Okayama University Medical School |
File Version | publisher |
Refereed | True |
PubMed ID | 23970320 |
Web of Science KeyUT | 000323470100003 |
JaLCDOI | 10.18926/AMO/51064 |
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FullText URL | 67_4_203.pdf |
Author | Ohuchi, Hideyo| |
Abstract | A central issue of evolutionary developmental biology is how the eye is diverged morphologically and functionally. However, the unifying mechanisms or schemes that govern eye diversification remain unsolved. In this review, I first introduce the concept of evolutionary developmental biology of the eye with a focus on photoreception, the fundamental property of retinal cells. Second, I summarize the early development of vertebrate eyes and the role of a homeobox gene, Lhx1, in subdivision of the retina into 2 domains, the neural retina and retinal pigmented epithelium of the optic primordium. The 2 retinal domains are essential components of the eye as they are found in such prototypic eyes as the extant planarian eye. Finally, I propose the presence of novel retinal cell subtypes with photosensory functions based on our recent work on atypical photopigments (opsins) in vertebrates. Since human diseases are attributable to the aberration of various types of cells due to alterations in gene expression, understanding the precise mechanisms of cellular diversification and unraveling the molecular profiles of cellular subtypes are essential to future regenerative medicine. |
Keywords | eye development evolution opsin photoreceptor |
Amo Type | Review |
Publication Title | Acta Medica Okayama |
Published Date | 2013-08 |
Volume | volume67 |
Issue | issue4 |
Publisher | Okayama University Medical School |
Start Page | 203 |
End Page | 212 |
ISSN | 0386-300X |
NCID | AA00508441 |
Content Type | Journal Article |
language | English |
Copyright Holders | CopyrightⒸ 2013 by Okayama University Medical School |
File Version | publisher |
Refereed | True |
PubMed ID | 23970318 |
Web of Science KeyUT | 000323470100001 |
Author | Tashiro, Keitaro| Satoh, Ayano| Utsumi, Teruo| Chung, Chuhan| Iwakiri, Yasuko| |
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Published Date | 2013-03 |
Publication Title | The American Journal of Pathology |
Volume | volume182 |
Issue | issue3 |
Content Type | Journal Article |
Author | Saito, T.| Nishida, K.| Furumatsu, T.| Yoshida, A.| Ozawa, M.| Ozaki, T.| |
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Published Date | 2013-01 |
Publication Title | Osteoarthritis and Cartilage |
Volume | volume21 |
Issue | issue1 |
Content Type | Journal Article |
Author | Koreishi, Mayuko| Gniadek, Thomas J.| Yu, Sidney| Masuda, Junko| Honjo, Yasuko| Satoh, Ayano| |
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Published Date | 2013-05-21 |
Publication Title | PLoS ONE |
Volume | volume8 |
Issue | issue3 |
Content Type | Journal Article |
Author | Miki, Yukari| Gion, Yuka| Mukae, Yuriko| Hayashi, Atsushi| Sato, Hiaki| Yoshino, Tadashi| Takahashi, Kiyoshi| |
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Published Date | 2013-02 |
Publication Title | European Journal of Haematology |
Volume | volume90 |
Issue | issue2 |
Content Type | Journal Article |
Author | Hayashi, Atsushi| Fumon, Takumi| Miki, Yukari| Sato, Hiaki| Yoshino, Tadashi| Takahashi, Kiyoshi| |
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Published Date | 2013-06 |
Publication Title | Journal of Clinical and Experimental Hematopathology |
Volume | volume53 |
Issue | issue1 |
Content Type | Journal Article |
Author | Mizote, Yu| |
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Published Date | 2013-03-25 |
Publication Title | |
Content Type | Thesis or Dissertation |
Author | Hayashi, Atsushi| |
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Published Date | 2013-03-25 |
Publication Title | |
Content Type | Thesis or Dissertation |
Author | Kiura, Katsuyuki| |
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Published Date | 2013-08-01 |
Publication Title | 岡山医学会雑誌 |
Volume | volume125 |
Issue | issue2 |
Content Type | Journal Article |
Author | Takata, Katsuyoshi| Sato, Yasuharu| Nakamura, Naoya| Tokunaka, Mami| Miki, Yukari| Kikuti, Yara Yukie| Igarashi, Kazuhiko| Ito, Etsuro| Harigae, Hideo| Kato, Seiichi| Hayashi, Eiko| Oka, Takashi| Hoshii, Yoshinobu| Tari, Akira| Okada, Hiroyuki| Mohamado, ABD Alkader Lamia| Maeda, Yoshinobu| Tanimoto, Mitsune| Kinoshita, Tomohiro| Yoshino, Tadashi| |
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Published Date | 2013-08-01 |
Publication Title | 岡山医学会雑誌 |
Volume | volume125 |
Issue | issue2 |
Content Type | Journal Article |
Author | Chino, Ayako| |
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Published Date | 2013-03-25 |
Publication Title | |
Content Type | Thesis or Dissertation |
Author | Okuma, Yu| Liu, Keyue| Wake, Hidenori| Haruma, Jun| Yoshino, Tadashi| Ohtsuka, Aiji| Takahashi, Hideo| Mori, Shuji| Nishibori, Masahiro| Date, Isao| |
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Published Date | 2013-08-01 |
Publication Title | 岡山医学会雑誌 |
Volume | volume125 |
Issue | issue2 |
Content Type | Journal Article |
Author | Nobuoka, Daisuke| Yoshikawa, Toshiaki| Takahashi, Mari| Iwama, Tatsuaki| Horie, Kazutaka| Shimomura, Manami| Suzuki, Shiro| Sakemura, Noriko| Nakatsugawa, Munehide| Sadamori, Hiroshi| Yagi, Takahito| Fujiwara, Toshiyoshi| Nakatsura, Tetsuya| |
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Published Date | 2013-04 |
Publication Title | Cancer Immunology, Immunotherapy |
Volume | volume62 |
Issue | issue4 |
Content Type | Journal Article |
Author | Ueno, Tsuyoshi| Tsukuda, Kazunori| Toyooka, Shinichi| Ando, Midori| Takaoka, Munenori| Soh, Junichi| Asano, Hiroaki| Maki, Yuho| Muraoka, Takayuki| Tanaka, Norimitsu| Shien, Kazuhiko| Furukawa, Masashi| Yamatsuji, Tomoki| Kiura, Katsuyuki| Naomoto, Yoshio| Miyoshi, Shinichiro| |
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Published Date | 2012-04 |
Publication Title | Lung Cancer |
Volume | volume76 |
Issue | issue1 |
Content Type | Journal Article |