ID | 31066 |
JaLCDOI | |
FullText URL | |
Author |
Haraoka, Shoichi
Saito, Daiji
Miyasaka, Minoru
Kawasaki, Tomoko
Yoshioka, Nobuhiko
Ikenaga, Toyotake
Okazaki, Satoru
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Abstract | The case of a patient with repeated attacks of collapse induced by sublingual isosorbide dinitrate is reported. The patient was an 81 year-old female who was admitted to Yura Hospital because of attacks of precordial pain. Several minutes after the sublingual administration of isosorbide dinitrate (10 mg) for an anginal attack, she developed a sensation of general weakness, and thereafter because unconscious. Arterial blood pressure fell and became unmeasurable. Electrocardiograms recorded during the syncopal attack showed sinus tachycardia and significant elevation of ST-segment in right precordial leads. In response to a drip infusion of noradrenaline, arterial blood pressure returned to normal with recovery of consciousness. Two similar syncopal attacks induced by sublingual isosorbide dinitrate occurred in the next three days. These attacks were not due to augmentation of the vagal reflex. Decrease of venous return probably was the primary etiological factor. |
Keywords | isosorbide dinitrate
syncopal attack hypotension
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Amo Type | Article
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Publication Title |
Acta Medica Okayama
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Published Date | 1978-10
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Volume | volume32
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Issue | issue5
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Publisher | Okayama University Medical School
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Start Page | 369
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End Page | 378
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ISSN | 0386-300X
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NCID | AA00508441
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Content Type |
Journal Article
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language |
English
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File Version | publisher
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Refereed |
True
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PubMed ID | |
NAID |