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ID 30319
JaLCDOI
FullText URL
Author
Takahashi, Isao
Oda, Yasuhiro
Lai, Minyu
Fukumoto, Mitsuhiro
Nishimura, Masataka
Yorimitsu, Seiichi
Kitajima, Koichi
Kimura, Ikuro
Abstract

The combined effect of human lymphoblastoid interferon (HLBI) and anticancer agents on the growth of MOLT-4 was studied in vitro. The interferon showed a strikingly synergistic interaction in combination with aclarubicin, cytosine arabinoside or prednisolone. It was moderately synergistic in combination with adriamycin or 5-fluorouracil and tended to show additive effects with daunorubicin or vincristine. In vitro studies of combination chemotherapy with interferon and anticancer agents should yield valuable information as to the best combination for man.

Keywords
human lymphoblastoid interferon
in vitro chemotherapy
interaction of anticancer agents
Amo Type
Article
Publication Title
Acta Medica Okayama
Published Date
1984-12
Volume
volume38
Issue
issue6
Publisher
Okayama University Medical School
Start Page
501
End Page
504
ISSN
0386-300X
NCID
AA00508441
Content Type
Journal Article
language
English
File Version
publisher
Refereed
True
PubMed ID
Web of Science KeyUT