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JaLCDOI 10.18926/AMO/48692
FullText URL 66_4_363.pdf
Author Tanaka, Masato| Sugimoto, Yoshihiro| Misawa, Haruo| Takigawa, Tomoyuki| Kunisada, Toshiyuki| Ozaki, Toshifumi|
Abstract Spinal deformity is an important clinical manifestation after surgery for spinal cord tumors. One-third of patients who receive laminectomies and irradiation of the spinal column develop scoliosis, kyphosis, or kyphoscoliosis. Recent reports indicate good results after scoliosis surgery using segmental pedicle screws and a navigation system, but these reported studies have not included surgery for post-laminectomy kyphosis. Hooks and wires are ineffective in such patients who undergo laminectomy, and there are also high perioperative risks with insertion of pedicle screws because landmarks have been lost. Here, we report on the 5-year follow-up of a 13-year-old male patient with post-laminectomy and post-irradiation thoracic kyphoscoliosis after surgical treatment of spinal astrocytoma. Posterior segmental pedicle screw fixation was performed safely using a computer-assisted technique. The authors present the first case report for treatment of this condition using a navigation system.
Keywords astrocytoma scoliosis kyphoscoliosis navigation segmental pedicle screw fixation
Amo Type Case Report
Publication Title Acta Medica Okayama
Published Date 2012-08
Volume volume66
Issue issue4
Publisher Okayama University Medical School
Start Page 363
End Page 368
ISSN 0386-300X
NCID AA00508441
Content Type Journal Article
language English
Copyright Holders CopyrightⒸ 2012 by Okayama University Medical School
File Version publisher
Refereed True
PubMed ID 22918210
Web of Science KeyUT 000307918900010
JaLCDOI 10.18926/AMO/48691
FullText URL 66_4_357.pdf
Author Shien, Kazuhiko| Shien, Tadahiko| Soh, Junichi| Ikeda, Hirokuni| Nogami, Tomohiro| Taira, Naruto| Doihara, Hiroyoshi| Miyoshi, Shinichiro|
Abstract Ectopic thymoma is considered to arise from ectopic thymus tissue deposited as a result of the abnormal mislocalization of thymus tissue during the embryonic stage. An 86-year-old man visited our hospital with chief complaints of hoarseness and a mass in his anterior neck. A preoperative needle biopsy of the mass did not yield a definitive diagnosis. A positron emission tomography (PET) study revealed heterogeneous accumulation of 18F-fluorodeoxyglucose (FDG) in the tumor. The tumor, affecting the left sternocleidomastoid muscle, the recurrent laryngeal nerve, the internal carotid vein, and the brachiocephalic vein, was resected using a combination of a collar incision in the neck and a median incision in the sternum. Immunohistochemically, the tumor was diagnosed as an ectopic thymoma of the neck. To date, only a few cases of ectopic thymoma presenting with FDG accumulation have been reported. Our experience indicates that ectopic thymoma should be kept in mind during the differential diagnosis of neck tumors with FDG accumulation appearing on PET images.
Keywords ectopic thymoma thyroid tumor positron emission tomography (PET)
Amo Type Case Report
Publication Title Acta Medica Okayama
Published Date 2012-08
Volume volume66
Issue issue4
Publisher Okayama University Medical School
Start Page 357
End Page 361
ISSN 0386-300X
NCID AA00508441
Content Type Journal Article
language English
Copyright Holders CopyrightⒸ 2012 by Okayama University Medical School
File Version publisher
Refereed True
PubMed ID 22918209
JaLCDOI 10.18926/AMO/48690
FullText URL 66_4_351.pdf
Author Ohara, Ichiyou| Ogata, Sho| Okusa, Yasushi| Ogawa, Tomomichi| Matsuzaki, Koji| Kaga, Hitoshi| Niihara, Naoko| Tominaga, Susumu| Hase, Kazuo|
Abstract In the duodenum, mixed exocrine-endocrine tumors exhibiting both neuroendocrine and glandular differentiations [cf. appendiceal goblet cell carcinoids (GCCs)] are rare. We present a Japanese case with a duodenal GCC that was found during pathologic examination of a gastrectomy specimen removed for gastric mucosal cancer. The tumor was widely distributed within both the first portion of the duodenum and the gastric antrum, although mucosal involvement was observed only in the duodenum. The tumor cells formed solid nests, trabeculae, or tubules, and some displayed a goblet cell appearance. They were immunoreactive against antibodies for both serotonin and somatostatin, and showed an argentaffin reaction (similar to a “midgut” enterochromaffin cell carcinoid). Ultra-structurally, the tumor cells had an amphicrine nature. Physicians encounter GCC in the duodenum only rarely, and its discovery may be incidental. Its diagnosis will be challenging and will require careful clinical and pathologic examinations.
Keywords amphicrine tumor duodenum goblet cell carcinoid serotonin somatostatin
Amo Type Case Report
Publication Title Acta Medica Okayama
Published Date 2012-08
Volume volume66
Issue issue4
Publisher Okayama University Medical School
Start Page 351
End Page 356
ISSN 0386-300X
NCID AA00508441
Content Type Journal Article
language English
Copyright Holders CopyrightⒸ 2012 by Okayama University Medical School
File Version publisher
Refereed True
PubMed ID 22918208
Web of Science KeyUT 000307918900008
JaLCDOI 10.18926/AMO/48689
FullText URL 66_4_343.pdf
Author Fujiwara, Takeo| Takao, Soshi| Iwase, Toshihide| Hamada, Jun| Kawachi, Ichiro|
Abstract Little is known about the association between social capital and child behaviors. This study aims to investigate that association. A complete population-based, cross-sectional survey was conducted for all the caregivers with preschool children in a rural town in Okayama prefecture in Japan. Two dimensions of individual-level social capital and unhealthy child behaviors were reported by parent-administered questionnaire. We analyzed 354 preschool children (57.6% of all children for whom questionnaires were completed). Children whose main caregiver had high cognitive social capital were 89% less likely to miss breakfast (odds ratio [OR]=0.11;95% confidence interval [CI]:0.01-1.03). Children whose caregiver had high structural social capital were 71% less likely to wake up late (OR=0.29;95% CI:0.12-0.71) and 78% less likely to skip tooth brushing more than once per day (OR=0.22;95% CI:0.05-0.93). Both cognitive and structural social capital were negatively associated with unhealthy child behaviors. A further intervention study is needed to confirm the impact of social capital on child behavior.
Keywords tooth brushing child health social capital skipping breakfast watching TV
Amo Type Original Article
Publication Title Acta Medica Okayama
Published Date 2012-08
Volume volume66
Issue issue4
Publisher Okayama University Medical School
Start Page 343
End Page 350
ISSN 0386-300X
NCID AA00508441
Content Type Journal Article
language English
Copyright Holders CopyrightⒸ 2012 by Okayama University Medical School
File Version publisher
Refereed True
PubMed ID 22918207
Web of Science KeyUT 000307918900007
JaLCDOI 10.18926/AMO/48688
FullText URL 66_4_335.pdf
Author Shiba, Naoki| Nagano, Osamu| Hirayama, Takahiro| Ichiba, Shingo| Ujike, Yoshihito|
Abstract In adult high-frequency oscillatory ventilation (HFOV) with an R100 artificial ventilator, exhaled gas from patientʼs lung may warm the temperature probe and thereby disturb the humidification of base flow (BF) gas. We measured the humidity of BF gas during HFOV with frequencies of 6, 8 and 10Hz, maximum stroke volumes (SV) of 285, 205, and 160ml at the respective frequencies, and, BFs of 20, 30, 40l/min using an original lung model. The R100 device was equipped with a heated humidifier, HummaxⅡ, consisting of a porous hollow fiber in circuit. A 50-cm length of circuit was added between temperature probe (located at 50cm proximal from Y-piece) and the hollow fiber. The lung model was made of a plastic container and a circuit equipped with another HummaxⅡ. The lung model temperature was controlled at 37℃. The HummaxⅡ of the R100 was inactivated in study-1 and was set at 35℃ or 37℃ in study-2. The humidity was measured at the distal end of the added circuit in study-1 and at the proximal end in study-2. In study-1, humidity was detected at 6Hz (SV 285ml) and BF 20l/min, indicating the direct reach of the exhaled gas from the lung model to the temperature probe. In study-2 the absolute humidity of the BF gas decreased by increasing SV and by increasing BF and it was low with setting of 35℃. In this study setting, increasing the SV induced significant reduction of humidification of the BF gas during HFOV with R100.
Keywords HFOV humidification
Amo Type Original Article
Publication Title Acta Medica Okayama
Published Date 2012-08
Volume volume66
Issue issue4
Publisher Okayama University Medical School
Start Page 335
End Page 341
ISSN 0386-300X
NCID AA00508441
Content Type Journal Article
language English
Copyright Holders CopyrightⒸ 2012 by Okayama University Medical School
File Version publisher
Refereed True
PubMed ID 22918206
Web of Science KeyUT 000307918900006
JaLCDOI 10.18926/AMO/48687
FullText URL 66_4_329.pdf
Author Matsushita, Koki| Mizushima, Takaaki| Shirahige, Akinori| Tanioka, Hiroaki| Sawa, Kiminari| Ochi, Koji| Tanimoto, Mitsune| Koide, Norio|
Abstract The relationship between pancreatic fibrosis and apoptosis of pancreatic acinar cells has not been fully elucidated. We reported that taurine had an anti-fibrotic effect in a dibutyltin dichloride (DBTC)-chronic pancreatitis model. However, the effect of taurine on apoptosis of pancreatic acinar cells is still unclear. Therefore, we examined apoptosis in DBTC-chronic pancreatitis and in the AR42J pancreatic acinar cell line with/without taurine. Pancreatic fibrosis was induced by a single administration of DBTC. Rats were fed a taurine-containing diet or a normal diet and were sacrificed at day 5. The AR42J pancreatic acinar cell line was incubated with/without DBTC with taurine chloramines. Apoptosis was determined by using terminal deoxynucleotidyl transferase-mediated dUTP-digoxigenin nick end labeling (TUNEL) assay. The expression of Bad and Bcl-2 proteins in the AR42J cells lysates was detected by Western blot analysis. The apoptotic index of pancreatic acinar cells in DBTC-administered rats was significantly increased. Taurine treatment inhibited pancreatic fibrosis and apoptosis of acinar cells induced by DBTC. The number of TUNEL-positive cells in the AR42J pancreatic acinar cell lines was significantly increased by the addition of DBTC. Incubation with taurine chloramines ameliorated these changes. In conclusion, taurine inhibits apoptosis of pancreatic acinar cells and pancreatitis in experimental chronic pancreatitis.
Keywords apoptosis chronic pancreatitis pancreatic acinar cells taurine
Amo Type Original Article
Publication Title Acta Medica Okayama
Published Date 2012-08
Volume volume66
Issue issue4
Publisher Okayama University Medical School
Start Page 329
End Page 334
ISSN 0386-300X
NCID AA00508441
Content Type Journal Article
language English
Copyright Holders CopyrightⒸ 2012 by Okayama University Medical School
File Version publisher
Refereed True
PubMed ID 22918205
Web of Science KeyUT 000307918900005
Related Url http://ousar.lib.okayama-u.ac.jp/metadata/49739
JaLCDOI 10.18926/AMO/48686
FullText URL 66_4_317.pdf
Author Pak, Wing| Takayama, Fusako| Hasegawa, Azusa| Mankura, Mitsumasa| Egashira, Toru| Ueki, Keiji| Nakamoto, Kazuo| Kawasaki, Hiromu| Mori, Akitane|
Abstract This study aimed to investigate the therapeutic effects of the water extract of leaves of Vitis coignetiae Pulliat (VCPL) on nonalcoholic steatohepatitis (NASH) with advanced fibrosis, as our previous study exhibited its preventive effect on NASH. The NASH animal model [PCT/JP2007/52477] was prepared by loading recurrent and intermittent hypoxemia stress to a rat with fatty liver, which resembled the condition occurring in patients with obstructive sleep apnea (OSA) and fatty liver, who have a high incidence of NASH. Intermittent hypoxemia stress is regarded as a condition similar to warm ischemia followed by re-oxygenation, which induces oxidative stress (OS). The daily 100 or 300mg/kg VCPL administrations were performed for 3 weeks perorally beginning at the time of detection of advanced liver fibrosis. The therapeutic efficacy of VCPL on NASH was demonstrated by the reduction of the leakage of hepato-biliary enzymes and the amelioration of liver fibrosis. The OS elevation in NASH rats was measured based on the derivation of reactive oxygen species from liver mitochondrial energy metabolism and on the decrease in plasma SOD-like activity. The aggravation of inflammatory responses was demonstrated by the neutrophil infiltration (elevated myeloperoxidase activity) and the progression of fibrosis in the livers of NASH rats. In addition, the NASH rats without VCPL treatment also exhibited activation of nuclear factor-κB, a key factor in the link between oxidative stress and inflammation. All of these changes were reduced dose-dependently by the VCPL administration. These findings indicate that VCPL may improve hepatic fibrosis or at least suppress the progression of NASH, by breaking the crosstalk between OS and inflammation.
Keywords non-alcoholic steatohepatitis antioxidative oxidative stress anti-inflammation Vitis coignetiae Pulliat
Amo Type Original Article
Publication Title Acta Medica Okayama
Published Date 2012-08
Volume volume66
Issue issue4
Publisher Okayama University Medical School
Start Page 317
End Page 327
ISSN 0386-300X
NCID AA00508441
Content Type Journal Article
language English
Copyright Holders CopyrightⒸ 2012 by Okayama University Medical School
File Version publisher
Refereed True
PubMed ID 22918204
Web of Science KeyUT 000307918900004
Title Alternative Au delà de l’ enchaînement de Berlin :sur la conception de liberté chez Jean-Fabien Spitz
FullText URL olj_057_1_095_177.pdf
Author Omori, H.|
Publication Title 岡山大學法學會雜誌
Published Date 2007-09-28
Volume volume57
Issue issue1
Start Page 95
End Page 177
ISSN 0386-3050
language Japanese
File Version publisher
NAID 40015672467
Title Alternative Electoral Reform in Britain
FullText URL olj_057_1_234_192.pdf
Author Narihiro, T.|
Publication Title 岡山大學法學會雜誌
Published Date 2007-09-28
Volume volume57
Issue issue1
Start Page 234
End Page 192
ISSN 0386-3050
language Japanese
File Version publisher
NAID 40015672471
Title Alternative Putinism :The Way of Russia to Democracy ?
FullText URL olj_057_1_282_236.pdf
Author Kawahara, Y.|
Publication Title 岡山大學法學會雜誌
Published Date 2007-09-28
Volume volume57
Issue issue1
Start Page 282
End Page 236
ISSN 0386-3050
language Japanese
File Version publisher
NAID 40015672470
Title Alternative L’assistance publique en France pendant la Révolution sous la Constituant et la Législative (2)
FullText URL olj_057_1_041_094.pdf
Author Hatano, S.|
Publication Title 岡山大學法學會雜誌
Published Date 2007-09-28
Volume volume57
Issue issue1
Start Page 41
End Page 94
ISSN 0386-3050
language Japanese
File Version publisher
NAID 40015672466
Title Alternative A Study on Surrender of Security by Creditor : Focusing on Case Law and Scholarly Opinion (3)
FullText URL olj_057_1_021_040.pdf
Author Tsuji, H.|
Publication Title 岡山大學法學會雜誌
Published Date 2007-09-28
Volume volume57
Issue issue1
Start Page 21
End Page 40
ISSN 0386-3050
language Japanese
File Version publisher
NAID 40015672465
Title Alternative A Study on Data Subjects’ Right of Access to Minors’ Personal Data and on Offer of Minors' Personal Data to the Parents
FullText URL olj_057_1_308_284.pdf
Author Nakamura, M.|
Publication Title 岡山大學法學會雜誌
Published Date 2007-09-28
Volume volume57
Issue issue1
Start Page 308
End Page 284
ISSN 0386-3050
language Japanese
File Version publisher
NAID 40015672469
FullText URL olj_057_1_332_310.pdf
Author Tani, Satomi|
Publication Title 岡山大學法學會雜誌
Published Date 2007-09-28
Volume volume57
Issue issue1
Start Page 332
End Page 310
ISSN 0386-3050
language English
File Version publisher
NAID 40015672468
Title Alternative A Study on Surrender of Security by Creditor : Focusing on Case Law and Scholarly Opinion (4)
FullText URL olj_057_2_455_476.pdf
Author Tsuji, H.|
Publication Title 岡山大學法學會雜誌
Published Date 2007-12-28
Volume volume57
Issue issue2
Start Page 455
End Page 476
ISSN 0386-3050
language Japanese
File Version publisher
NAID 40015825564
Title Alternative A Study on Asbestos Litigation (1):Focusing on Epidemiologic Causality
FullText URL olj_057_2_399_412.pdf
Author Tsuji, H.|
Publication Title 岡山大學法學會雜誌
Published Date 2007-12-28
Volume volume57
Issue issue2
Start Page 399
End Page 412
ISSN 0386-3050
language Japanese
File Version publisher
NAID 40015825562
Title Alternative The Dimension of Polis-Respublica-State in Aristotle’s Politics
FullText URL olj_057_2_335_398.pdf
Author Araki, M.|
Publication Title 岡山大學法學會雜誌
Published Date 2007-12-28
Volume volume57
Issue issue2
Start Page 335
End Page 398
ISSN 0386-3050
language Japanese
File Version publisher
NAID 40015825561
Title Alternative A Study on Surrender of Security by Creditor : Focusing on Case Law and Scholarly Opinion (5)
FullText URL olj_057_3_573_592.pdf
Author Tsuji, H.|
Publication Title 岡山大學法學會雜誌
Published Date 2008-03-05
Volume volume57
Issue issue3
Start Page 573
End Page 592
ISSN 0386-3050
language Japanese
File Version publisher
NAID 40015946197
Title Alternative The Process of Democratisation in the Repablic of Estonia after Independence and the Arguement on Political Culture
FullText URL olj_057_3_658_636.pdf
Author Kawahara, Y.|
Publication Title 岡山大學法學會雜誌
Published Date 2008-03-05
Volume volume57
Issue issue3
Start Page 658
End Page 636
ISSN 0386-3050
language Japanese
File Version publisher
NAID 40015946199
Title Alternative A Study on Surrender of Security by Creditor : Focusing on Case Law and Scholarly Opinion (6)
FullText URL olj_057_4_683_706.pdf
Author Tsuji, H.|
Publication Title 岡山大學法學會雜誌
Published Date 2008-03-24
Volume volume57
Issue issue4
Start Page 683
End Page 706
ISSN 0386-3050
language Japanese
File Version publisher
NAID 40015946202