result 3387 件
Author | Yabe, Ryo| Nguyen Quang Co| Trinh Thi Sen| Saitoh, Kuniyuki| |
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Published Date | 2015-02-01 |
Publication Title | 岡山大学農学部学術報告 |
Volume | volume104 |
Content Type | Departmental Bulletin Paper |
Author | Peyghan, Esmaeil| Nasrabadi, Hassan| Tayebi, Akbar| |
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Published Date | 2015-01 |
Publication Title | Mathematical Journal of Okayama University |
Volume | volume57 |
Issue | issue1 |
Content Type | Journal Article |
JaLCDOI | 10.18926/mjou/53046 |
Author | Kör, Arda| Quynh, Truong Cong| Şahinkaya, Serap| Koşan, Muhammet Tamer| |
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Published Date | 2015-01 |
Publication Title | Mathematical Journal of Okayama University |
Volume | volume57 |
Issue | issue1 |
Content Type | Journal Article |
JaLCDOI | 10.18926/mjou/53042 |
Title Alternative | Die Intellekutelle und die `Bildung' : Der Bildungsgedanke von Maruyama Masao |
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FullText URL | olj_064_2_269_317.pdf |
Author | Nishimura, M.| |
Publication Title | 岡山大學法學會雜誌 |
Published Date | 2014-12-26 |
Volume | volume64 |
Issue | issue2 |
Start Page | 269 |
End Page | 317 |
ISSN | 0386-3050 |
language | Japanese |
File Version | publisher |
NAID | 120005525337 |
FullText URL | olj_064_2_388_349.pdf |
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Author | Takeuchi, M.| |
Publication Title | 岡山大學法學會雜誌 |
Published Date | 2014-12-26 |
Volume | volume64 |
Issue | issue2 |
Start Page | 388 |
End Page | 349 |
ISSN | 0386-3050 |
language | English |
File Version | publisher |
NAID | 120005525334 |
JaLCDOI | 10.18926/AMO/53028 |
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FullText URL | 68_6_379.pdf |
Author | Doi, Shinichiro| Kimura, Shuhei| Morizane, Yuki| Hosogi, Mika| Hosokawa, Mio| Shiode, Yusuke| Kawata, Tetsuhiro| Kondo, Eisei| Shiraga, Fumio| |
Abstract | We report a case of POEMS syndrome in a 20-year-old patient diagnosed after visiting an eye clinic with a chief complaint of reduced visual acuity. A male university student aged 20 years was referred to our department complaining of blurred vision in both eyes that had persisted for 1 month. He also noted headache, nausea, and paresthesia in the lower extremities around the same time. The visual acuity of his right and left eye was 20/40 and 20/20, respectively. Optic disc edema and serous retinal detachment were present. Brain magnetic resonance imaging showed no intracranial abnormalities, while elevated cerebrospinal fluid pressure, reduced nerve conduction velocity in both lower extremities, hepatosplenomegaly, M proteinemia, high blood VEGF levels, osteoblastic and osteolytic changes in the spine, and atypical plasma cells in bone lesions were noted. From the above findings, the patient was diagnosed with POEMS syndrome. He received high-dose dexamethasone, thalidomide, and radiotherapy on the sacral mass, followed by high-dose melphalan with autologous stem-cell support, and showed subsequent systemic and ophthalmologic improvement. Here, we report the youngest case ever of POEMS syndrome with ocular manifestation. If patients have optic disc edema in both eyes with no intracranial space-occupying lesion, POEMS syndrome should be considered in differential diagnosis, regardless of age. |
Keywords | POEMS syndrome serous retinal detachment VEGF |
Amo Type | Case Report |
Publication Title | Acta Medica Okayama |
Published Date | 2014-12 |
Volume | volume68 |
Issue | issue6 |
Publisher | Okayama University Medical School |
Start Page | 379 |
End Page | 383 |
ISSN | 0386-300X |
NCID | AA00508441 |
Content Type | Journal Article |
language | English |
Copyright Holders | CopyrightⒸ 2014 by Okayama University Medical School |
File Version | publisher |
Refereed | True |
PubMed ID | 25519033 |
Web of Science KeyUT | 000346882200009 |
Author | Kobayashi, Tomoko| Suzuki, Etsuji| Oksanen, Tuula| Kawachi, Ichiro| Takao, Soshi| |
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Published Date | 2014-01-31 |
Publication Title | PLoS ONE |
Volume | volume9 |
Issue | issue1 |
Content Type | Journal Article |
Author | Alamusi| Matsuo, Toshihiko| Hosoya, Osamu| Tsutsui, Kimiko M.| Uchida, Tetsuya| |
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Published Date | 2013-09 |
Publication Title | Journal of Artificial Organs |
Volume | volume16 |
Issue | issue3 |
Content Type | Journal Article |
Title Alternative | Drug interaction (31. drug interaction in hormonal breast cancer therapy) |
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FullText URL | 126_245.pdf |
Author | Masaoka, Yasuyuki| Kitamura, Yoshihisa| Sendo, Toshiaki| |
Publication Title | 岡山医学会雑誌 |
Published Date | 2014-12-01 |
Volume | volume126 |
Issue | issue3 |
Start Page | 245 |
End Page | 248 |
ISSN | 0030-1558 |
language | Japanese |
Copyright Holders | Copyright (c) 2014 岡山医学会 |
File Version | publisher |
DOI | 10.4044/joma.126.245 |
NAID | 130004903247 |
Author | Kataoka, Yuko| Nishizaki, Kazunori| |
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Published Date | 2014-12-01 |
Publication Title | 岡山医学会雑誌 |
Volume | volume126 |
Issue | issue3 |
Content Type | Journal Article |
Title Alternative | Molecular target therapies in rheumatic diseases |
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FullText URL | 126_227.pdf |
Author | Wakabayashi, Hiroshi| |
Keywords | リウマチ性疾患 自己免疫疾患 生物学的製剤 分子標的薬 |
Publication Title | 岡山医学会雑誌 |
Published Date | 2014-12-01 |
Volume | volume126 |
Issue | issue3 |
Start Page | 227 |
End Page | 230 |
ISSN | 0030-1558 |
language | Japanese |
Copyright Holders | Copyright (c) 2014 岡山医学会 |
File Version | publisher |
DOI | 10.4044/joma.126.227 |
NAID | 130004903237 |
Title Alternative | A case of microscopic low-grade appendiceal mucinous neoplasm complicated with appendicitis resected by reduced-port laparoscopic surgery |
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FullText URL | 126_223.pdf |
Author | Suzuki, Hiromitsu| Kimura, Kouji| Kinoshita, Sigeki| Okano, Kazuo| |
Abstract | Appendicitis is a benign disease for which surgical treatment is widely provided. The complication of neoplastic lesions may be discovered only after resection. However, in some cases, specimens are not submitted to histopathological examination in Japan because of an extreme deficiency of pathologists. We report our experience with one patient who experienced the complication of latent low-grade appendiceal mucinous neoplasm (LAMN) after surgery for appendicitis. Our patient was an 85-year-old woman. Conservative treatment failed to relieve fever and lower abdominal pain and it was decided to treat her surgically. Abdominal computed tomography (CT) showed appendicitis with severe inflammation and suspected adhesion. We decided to explore the abdominal cavity using a reduced-port laparoscopic approach. We found no mucous debouchment or clear tumors in the specimen. Histopathological findings indicated the coexistence of appendicitis and LAMN. At one year and a half after surgery, there was no evidence of the development of pseudomyxoma peritonei. In appendectomy, it is thought that careful perioperative treatment and a postoperative pathological search are important when there are no preoperative findings suggesting a neoplastic lesion. |
Keywords | 虫垂炎(appendicitis) 減孔式腹腔鏡手術(reduced-port laparoscopic surgery) 虫垂粘液嚢胞腺腫(low-grade appendiceal mucinous neoplasm (LAMN)) 腹膜偽粘液腫(pseudomyxoma peritonei) 腹腔鏡下虫垂切除術(laparoscopic appendectomy) |
Publication Title | 岡山医学会雑誌 |
Published Date | 2014-12-01 |
Volume | volume126 |
Issue | issue3 |
Start Page | 223 |
End Page | 226 |
ISSN | 0030-1558 |
language | Japanese |
Copyright Holders | Copyright (c) 2014 岡山医学会 |
File Version | publisher |
DOI | 10.4044/joma.126.223 |
NAID | 130004903238 |
Title Alternative | Giant rectal gastrointestinal stromal tumor successfully resected by abdominoperineal resection combined with posterior vaginal wall resection |
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FullText URL | 126_217.pdf |
Author | Iwakawa, Kazuhide| Nishie, Manabu| Tokunaga, Naoyuki| Miyaso, Hideaki| Iwagaki, Hiromi| |
Abstract | We report a case of giant rectal gastrointestinal stromal tumor (GIST) successfully resected by abdominoperineal resection combined with posterior vaginal wall resection. Our patient was a 79-year-old woman had been diagnosed as having von Recklinghausen disease at the age of 30 years. In 2006, a computed tomography (CT) scan revealed a tumor originating from the posterior wall of the rectum. In June 2010, she was admitted to our hospital with the chief complaint of bloody stool. A CT scan revealed a giant tumor that had increased to 9cm in size. Colonoscopy demonstrated a submucosal tumor, which was subsequently diagnosed by biopsy as a GIST. Due to the patient's continuous bleeding and abdominal pain, an emergent abdominoperineal resection was performed at that time. The tumor, which measured 8×9cm, was immunohistochemically positive for c-kit and CD34. Concomitant resection of the posterior wall of the vagina via the perineal approach provided a wide area to expose the tumor for a safe operation. The patient has been well with no sign of recurrence since the operation. This procedure is recommended as a useful approach for giant rectal GISTs or rectal cancer with invasion of the posterior pelvic wall. |
Keywords | 巨大直腸GIST(giant rectal GIST) 腹会陰式直腸切断術(abdominoperineal resection) |
Publication Title | 岡山医学会雑誌 |
Published Date | 2014-12-01 |
Volume | volume126 |
Issue | issue3 |
Start Page | 217 |
End Page | 221 |
ISSN | 0030-1558 |
language | Japanese |
Copyright Holders | Copyright (c) 2014 岡山医学会 |
File Version | publisher |
DOI | 10.4044/joma.126.217 |
NAID | 130004903245 |
Title Alternative | Hospital and clinic cooperation for the treatment of rheumatoid arthritis in Okayama Prefecture, Japan |
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FullText URL | 126_209.pdf |
Author | Sada, Ken-ei| Nishida, Keiichiro| Yamanaka, Takao| Misaki, Kenta| Wakabayashi, Hiroshi| Shinoda, Junko| Takagi, Toru| Yano, Ryusuke| Nakamura, Akihiko| Nanba, Yoshifumi| Morita, Yoshitaka| Koyama, Yoshinobu| Yamamoto, Keiji| Ezawa, Kazuhiko| Ota, Yusuke| Yoshihara, Yoshiki| Miyoshi, Shinya| Natsumeda, Masamitsu| Usui, Masaaki| Yoshinaga, Yasuhiko| Hayashi, Takashi| Yamamura, Masahiro| Hashizume, Hiroyuki| |
Abstract | Objective: To survey the current status and problems of cooperation between clinics and hospitals in Okayama Prefecture, Japan for the treatment of rheumatoid arthritis (RA). Methods: We distributed a questionnaire to 300 of the 983 Okayama Prefecture clinics that had either an internal medicine or orthopedic surgery department, from December 2013 to February 2014. The questionnaire covered practice pattern for RA treatment in clinics, current status of the hospital and clinic cooperation, and acceptance of the biologic therapy. Results: One hundred clinics responded to the questionnaire. Seventy percent of the clinics reported making referrals to rheumatologists before the initiation of RA treatment, and half of the other 30% of the clinics administered methotrexate as the first-line treatment for RA by their own decision. Sixty-six clinics cooperated with flagship hospitals, conducting medical and laboratory examinations, providing prescriptions, and treating common diseases of patients. These clinics expected the cooperating rheumatologists to follow-up patients every 3 to 6 months and to make the diagnosis, make decisions regarding RA treatment changes, and perform surgery. Seventy-one percent of the clinics responded that cooperation with a hospital is possible even for patients who are administered biologics. As reasons for no cooperation with the flagship hospitals, clinics noted the lack of information about rheumatologists in the area and recent trends in the management of RA. Conclusion: The current study reported, for the first time, the actual conditions of management of RA in clinics, as well as future problems of hospital and clinic cooperation in Okayama Prefecture. |
Keywords | 病診連携(hospital and clinic cooperation) 関節リウマチ(rheumatoid arthritis) 生物学的製剤(biologics) メトトレキサート(methotrexate) |
Publication Title | 岡山医学会雑誌 |
Published Date | 2014-12-01 |
Volume | volume126 |
Issue | issue3 |
Start Page | 209 |
End Page | 215 |
ISSN | 0030-1558 |
language | Japanese |
Copyright Holders | Copyright (c) 2014 岡山医学会 |
File Version | publisher |
DOI | 10.4044/joma.126.209 |
NAID | 130004903246 |
Title Alternative | Modulation of neuronal function and neuroprotection by astrocytes |
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FullText URL | 126_203.pdf |
Author | Asanuma, Masato| |
Keywords | アストロサイト 抗酸化防御機構 パーキンソン病 メタロチオネイン Nrf2 |
Publication Title | 岡山医学会雑誌 |
Published Date | 2014-12-01 |
Volume | volume126 |
Issue | issue3 |
Start Page | 203 |
End Page | 208 |
ISSN | 0030-1558 |
language | Japanese |
Copyright Holders | Copyright (c) 2014 岡山医学会 |
File Version | publisher |
DOI | 10.4044/joma.126.203 |
NAID | 130004903243 |
Title Alternative | The 2013 Incentive Award of the Okayama Medical Association in Cardiovascular and Pulmonary Research (2013 Sunada Prize) |
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FullText URL | 126_199.pdf |
Author | Shinaoka, Akira| |
Abstract | 受賞論文: Shinaoka A, Momota R, Shiratsuchi E, Kosaka M, Kumagishi K, Nakahara R, Naito I, Ohtsuka A:Architecture of the subendothelial elastic fibers of small blood vessels and variations in vascular type and size. Microsc Microanal (2013) 19, 406-414. |
Publication Title | 岡山医学会雑誌 |
Published Date | 2014-12-01 |
Volume | volume126 |
Issue | issue3 |
Start Page | 199 |
End Page | 201 |
ISSN | 0030-1558 |
language | Japanese |
Copyright Holders | Copyright (c) 2014 岡山医学会 |
File Version | publisher |
DOI | 10.4044/joma.126.199 |
NAID | 130004903244 |
Title Alternative | The 2013 Incentive Award of the Okayama Medical Association in Cardiovascular and Pulmonary Research (2013 Sunada Prize) |
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FullText URL | 126_195.pdf |
Author | Akagi, Satoshi| |
Abstract | 受賞対象論文: Akagi S, Nakamura K, Matsubara H, Kusano KF, Kataoka N, Oto T, Miyaji K, Miura A, Ogawa A, Yoshida M, Ueda-Ishibashi H, Yutani C, Ito H:Prostaglandin I2 induces apoptosis via upregulation of Fas ligand in pulmonary artery smooth muscle cells from patients with idiopathic pulmonary arterial hypertension. Int J Cardiol (2013) 165, 499-505. |
Publication Title | 岡山医学会雑誌 |
Published Date | 2014-12-01 |
Volume | volume126 |
Issue | issue3 |
Start Page | 195 |
End Page | 197 |
ISSN | 0030-1558 |
language | Japanese |
Copyright Holders | Copyright (c) 2014 岡山医学会 |
File Version | publisher |
DOI | 10.4044/joma.126.195 |
NAID | 130004903242 |
Title Alternative | The 2013 Incentive Award of the Okayama Medical Association in Cancer Research (2013 Hayashibara Prize and Yamada Prize) |
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FullText URL | 126_191.pdf |
Author | Shien, Kazuhiko| |
Abstract | 受賞対象論文: Shien K, Toyooka S, Yamamoto H, Soh J, Jida M, Thu KL, Hashida S, Maki Y, Ichihara E, Asano H, Tsukuda K, Takigawa N, Kiura K, Gazdar AF, Lam WL, Miyoshi S:Acquired resistance to EGFR inhibitors is associated with a manifestation of stem cell-like properties in cancer cells. Cancer Res (2013) 73, 3051-3061. |
Publication Title | 岡山医学会雑誌 |
Published Date | 2014-12-01 |
Volume | volume126 |
Issue | issue3 |
Start Page | 191 |
End Page | 194 |
ISSN | 0030-1558 |
language | Japanese |
Copyright Holders | Copyright (c) 2014 岡山医学会 |
File Version | publisher |
DOI | 10.4044/joma.126.191 |
NAID | 130004903236 |
Title Alternative | The 2013 Incentive Award of the Okayama Medical Association in General Medical Science (2013 Yuuki Prize) |
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FullText URL | 126_187.pdf |
Author | Yamamoto, Hiromasa| |
Abstract | 受賞対象論文: Yamamoto H, Higasa K, Sakaguchi M, Shien K, Soh J, Ichimura K, Furukawa M, Hashida S, Tsukuda K, Takigawa N, Matsuo K, Kiura K, Miyoshi S, Matsuda F, Toyooka S:Novel germline mutation in the transmembrane domain of HER2 in familial lung adenocarcinomas. J Natl Cancer Inst (2014) 106, djt338 |
Publication Title | 岡山医学会雑誌 |
Published Date | 2014-12-01 |
Volume | volume126 |
Issue | issue3 |
Start Page | 187 |
End Page | 190 |
ISSN | 0030-1558 |
language | Japanese |
Copyright Holders | Copyright (c) 2014 岡山医学会 |
File Version | publisher |
DOI | 10.4044/joma.126.187 |
NAID | 130004903235 |
Author | Arata, T| Okitsu, T| Fukazawa, T| Ikeda, H| Kobayashi, K| Yong, C| Kosaka, Y| Narushima, M| Matsuoka, J| Yamamoto, I| Tanaka, N| Lakey, JRT| Kobayashi, N| |
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Published Date | 2004-06 |
Publication Title | Artificial Organs |
Volume | volume28 |
Issue | issue6 |
Content Type | Journal Article |