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Author Nishi, Emiko|
Published Date 1959-11-20
Publication Title 岡山医学会雑誌
Volume volume71
Issue issue12-1
Content Type Journal Article
JaLCDOI 10.18926/AMO/41327
FullText URL 64_6_407.pdf
Author Ogata, Sho| Horio, Takuya| Sugiura, Yoshiaki| Shimazaki, Hideyuki| Saito, Hiroki| Aiko, Satoshi| Nakanishi, Kuniaki| Kawai, Toshiaki|
Abstract Sarcoidosis is a systemic granulomatous inflammation of unknown etiology, and seems to involve the liver parenchyma in most cases. However, sarcoidosis-associated hepatocellular carcinoma is rare. We report here a case in which a hepatocellular carcinoma occurred within the liver, which was probably involved as a result of systemic sarcoidosis. A 57-year-old Japanese man had been followed up for 2 years because of diabetic nephropathy and sarcoidosis. On admission for pneumonia, imaging studies revealed an unexpected hepatic tumor. Histology revealed a hepatocellular carcinoma accompanied by T-lymphocytic infiltration and marked granulomatous inflammation, which was surrounding some tumor nodules. The background liver parenchyma exhibited a moderate degree of fibrosis with granulomatous inflammation. The patient had no other apparent liver disease such as viral hepatitis, steatohepatitis, or primary biliary cirrhosis. Therefore, in the present case, sarcoidosis may be considered the probable background etiology for hepatocarcinogenesis.
Keywords granuloma hepatocellular carcinoma lymphocytic infiltration sarcoidosis
Amo Type Case Report
Publication Title Acta Medica Okayama
Published Date 2010-12
Volume volume64
Issue issue6
Publisher Okayama University Medical School
Start Page 407
End Page 410
ISSN 0386-300X
NCID AA00508441
Content Type Journal Article
language English
Copyright Holders Okayama University Medical School
File Version publisher
Refereed True
PubMed ID 21173811
Web of Science KeyUT 000285664200008
JaLCDOI 10.18926/AMO/41324
FullText URL 64_6_385.pdf
Author Miyatake, Nobuyuki| Moriyasu, Hideyuki| Sakano, Noriko| Tada, Shinya| Suzue, Takeshi| Hirao, Tomohiro|
Abstract The link between changes in estimated glomerular filtration rate (eGFR) and cigarette smoking was evaluated in Japanese male workers with a 5-year follow-up. We examined the data of 456 Japanese male workers, aged 22-70 years, who were taking no medications, and from this group, 286 men (43.5±8.2 years) were followed for 5-years. Habits of cigarette smoking were obtained during interviews by well-trained staff. The influence of cigarette smoking on eGFR was evaluated. In the first analysis, there was no significant difference in eGFR between subjects with and without cigarette smoking. In the second analysis, eGFR was significantly reduced after 5 years in all subjects. Changes in eGFR in subjects with cigarette smoking (-1.90±12.31ml/min/1.73m2) were significantly smaller than those in subjects without cigarette smoking (-4.97±12.05ml/min/1.73m2). At follow-up, we found that eGFR was weakly and negatively correlated with the number of cigarettes smoked (/day). The present study indicated that cigarette smoking may be an important modifiable factor for eGFR in Japanese male workers who are not taking any medications.
Keywords cigarette smoking estimated glomerular filtration rate (eGFR) male worker
Amo Type Original Article
Publication Title Acta Medica Okayama
Published Date 2010-12
Volume volume64
Issue issue6
Publisher Okayama University Medical School
Start Page 385
End Page 390
ISSN 0386-300X
NCID AA00508441
Content Type Journal Article
language English
Copyright Holders Okayama University Medical School
File Version publisher
Refereed True
PubMed ID 21173808
Web of Science KeyUT 000285664200005
JaLCDOI 10.18926/AMO/41322
FullText URL 64_6_367.pdf
Author Tantular, Indah S.| Matsuoka, Hiroyuki| Kasahara, Yuichi| Pusarawati, Suhintam| Kanbe, Toshio| Tuda, Josef S. B.| Kido, Yasutoshi| Dachlan, Yoes P.| Kawamoto, Fumihiko|
Abstract We conducted a field survey of glucose-6-phosphate dehydrogenese (G6PD) deficiency in the eastern Indonesian islands, and analyzed G6PD variants molecularly. The incidence of G6PD deficiency in 5 ethnic groups (Manggarai, Bajawa, Nage-Keo, Larantuka, and Palue) on the Flores and Palue Islands was lower than that of another native group, Sikka, or a nonnative group, Riung. Molecular analysis of G6PD variants indicated that 19 cases in Sikka had a frequency distribution of G6PD variants similar to those in our previous studies, while 8 cases in Riung had a different frequency distribution of G6PD variants. On the other hand, from field surveys in another 8 ethnic groups (Timorese, Sumbanese, Savunese, Kendari, Buton, Muna, Minahasa, and Sangirese) on the islands of West Timor, Sumba, Sulawesi, Muna and Bangka, a total of 49 deficient cases were detected. Thirty-nine of these 49 cases had G6PD Vanua Lava (383T>C) of Melanesian origin. In our previous studies, many cases of G6PD Vanua Lava were found on other eastern Indonesian islands. Taken together, these findings may indicate that G6PD Vanua Lava is the most common variant in eastern Indonesian populations, except for Sikka.
Keywords Glucose-6-phosphate dehydrogenase deficiency rapid G6PD test eastern Indonesian population molecular analysis G6PD Vanua Lava
Amo Type Original Article
Publication Title Acta Medica Okayama
Published Date 2010-12
Volume volume64
Issue issue6
Publisher Okayama University Medical School
Start Page 367
End Page 373
ISSN 0386-300X
NCID AA00508441
Content Type Journal Article
language English
Copyright Holders Okayama University Medical School
File Version publisher
Refereed True
PubMed ID 21173806
Web of Science KeyUT 000285664200003
Author Fujioka, Yukio| Fukui, Tetsuya| Kobayashi, Toshiyuki|
Published Date 1959-10-30
Publication Title 岡山医学会雑誌
Volume volume71
Issue issue11-2
Content Type Journal Article
Author Tokiya, Tatsuo|
Published Date 1959-10-30
Publication Title 岡山医学会雑誌
Volume volume71
Issue issue11-2
Content Type Journal Article
Author Murashima, Fusao|
Published Date 1959-10-30
Publication Title 岡山医学会雑誌
Volume volume71
Issue issue11-2
Content Type Journal Article
Author Izumi, Masaaki|
Published Date 1959-09-20
Publication Title 岡山医学会雑誌
Volume volume71
Issue issue10-1
Content Type Journal Article
Author Kuroda, Akio| Jinzenji, Kei| Yamamoto, Takashi| Kondo, Kazuji| Shoda, Junzo|
Published Date 1959-09-20
Publication Title 岡山医学会雑誌
Volume volume71
Issue issue10-1
Content Type Journal Article
Author Matsui, Toshiyuki|
Published Date 1959-09-10
Publication Title 岡山医学会雑誌
Volume volume71
Issue issue9-2
Content Type Journal Article
Author Sakurai, Yasuo|
Published Date 1959-09-10
Publication Title 岡山医学会雑誌
Volume volume71
Issue issue9-2
Content Type Journal Article
Author Uématsu, Yoshinori|
Published Date 1959-09-10
Publication Title 岡山医学会雑誌
Volume volume71
Issue issue9-2
Content Type Journal Article
Author Shiraishi, Yoshio|
Published Date 1959-09-10
Publication Title 岡山医学会雑誌
Volume volume71
Issue issue9-2
Content Type Journal Article
Author Naito, Takakazu|
Published Date 1959-08-15
Publication Title 岡山医学会雑誌
Volume volume71
Issue issue8-2
Content Type Journal Article
Author Nagamatsu, Hiroshi|
Published Date 1959-08-15
Publication Title 岡山医学会雑誌
Volume volume71
Issue issue8-2
Content Type Journal Article
Author Mitsufuji, Yasuteru|
Published Date 1959-08-10
Publication Title 岡山医学会雑誌
Volume volume71
Issue issue8-1
Content Type Journal Article
Author Okajima, Kunio|
Published Date 1959-07-10
Publication Title 岡山医学会雑誌
Volume volume71
Issue issue7-2
Content Type Journal Article
Author Mitsufuji, Yasuteru|
Published Date 1959-07-10
Publication Title 岡山医学会雑誌
Volume volume71
Issue issue7-2
Content Type Journal Article
Author Nakayama, Akitoshi|
Published Date 1959-06-30
Publication Title 岡山医学会雑誌
Volume volume71
Issue issue7-1
Content Type Journal Article
Author Okumura, Kazutoshi|
Published Date 1959-06-30
Publication Title 岡山医学会雑誌
Volume volume71
Issue issue7-1
Content Type Journal Article