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Author | Nishi, Emiko| |
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Published Date | 1959-11-20 |
Publication Title | 岡山医学会雑誌 |
Volume | volume71 |
Issue | issue12-1 |
Content Type | Journal Article |
JaLCDOI | 10.18926/AMO/41327 |
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FullText URL | 64_6_407.pdf |
Author | Ogata, Sho| Horio, Takuya| Sugiura, Yoshiaki| Shimazaki, Hideyuki| Saito, Hiroki| Aiko, Satoshi| Nakanishi, Kuniaki| Kawai, Toshiaki| |
Abstract | Sarcoidosis is a systemic granulomatous inflammation of unknown etiology, and seems to involve the liver parenchyma in most cases. However, sarcoidosis-associated hepatocellular carcinoma is rare. We report here a case in which a hepatocellular carcinoma occurred within the liver, which was probably involved as a result of systemic sarcoidosis. A 57-year-old Japanese man had been followed up for 2 years because of diabetic nephropathy and sarcoidosis. On admission for pneumonia, imaging studies revealed an unexpected hepatic tumor. Histology revealed a hepatocellular carcinoma accompanied by T-lymphocytic infiltration and marked granulomatous inflammation, which was surrounding some tumor nodules. The background liver parenchyma exhibited a moderate degree of fibrosis with granulomatous inflammation. The patient had no other apparent liver disease such as viral hepatitis, steatohepatitis, or primary biliary cirrhosis. Therefore, in the present case, sarcoidosis may be considered the probable background etiology for hepatocarcinogenesis. |
Keywords | granuloma hepatocellular carcinoma lymphocytic infiltration sarcoidosis |
Amo Type | Case Report |
Publication Title | Acta Medica Okayama |
Published Date | 2010-12 |
Volume | volume64 |
Issue | issue6 |
Publisher | Okayama University Medical School |
Start Page | 407 |
End Page | 410 |
ISSN | 0386-300X |
NCID | AA00508441 |
Content Type | Journal Article |
language | English |
Copyright Holders | Okayama University Medical School |
File Version | publisher |
Refereed | True |
PubMed ID | 21173811 |
Web of Science KeyUT | 000285664200008 |
JaLCDOI | 10.18926/AMO/41324 |
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FullText URL | 64_6_385.pdf |
Author | Miyatake, Nobuyuki| Moriyasu, Hideyuki| Sakano, Noriko| Tada, Shinya| Suzue, Takeshi| Hirao, Tomohiro| |
Abstract | The link between changes in estimated glomerular filtration rate (eGFR) and cigarette smoking was evaluated in Japanese male workers with a 5-year follow-up. We examined the data of 456 Japanese male workers, aged 22-70 years, who were taking no medications, and from this group, 286 men (43.5±8.2 years) were followed for 5-years. Habits of cigarette smoking were obtained during interviews by well-trained staff. The influence of cigarette smoking on eGFR was evaluated. In the first analysis, there was no significant difference in eGFR between subjects with and without cigarette smoking. In the second analysis, eGFR was significantly reduced after 5 years in all subjects. Changes in eGFR in subjects with cigarette smoking (-1.90±12.31ml/min/1.73m2) were significantly smaller than those in subjects without cigarette smoking (-4.97±12.05ml/min/1.73m2). At follow-up, we found that eGFR was weakly and negatively correlated with the number of cigarettes smoked (/day). The present study indicated that cigarette smoking may be an important modifiable factor for eGFR in Japanese male workers who are not taking any medications. |
Keywords | cigarette smoking estimated glomerular filtration rate (eGFR) male worker |
Amo Type | Original Article |
Publication Title | Acta Medica Okayama |
Published Date | 2010-12 |
Volume | volume64 |
Issue | issue6 |
Publisher | Okayama University Medical School |
Start Page | 385 |
End Page | 390 |
ISSN | 0386-300X |
NCID | AA00508441 |
Content Type | Journal Article |
language | English |
Copyright Holders | Okayama University Medical School |
File Version | publisher |
Refereed | True |
PubMed ID | 21173808 |
Web of Science KeyUT | 000285664200005 |
JaLCDOI | 10.18926/AMO/41322 |
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FullText URL | 64_6_367.pdf |
Author | Tantular, Indah S.| Matsuoka, Hiroyuki| Kasahara, Yuichi| Pusarawati, Suhintam| Kanbe, Toshio| Tuda, Josef S. B.| Kido, Yasutoshi| Dachlan, Yoes P.| Kawamoto, Fumihiko| |
Abstract | We conducted a field survey of glucose-6-phosphate dehydrogenese (G6PD) deficiency in the eastern Indonesian islands, and analyzed G6PD variants molecularly. The incidence of G6PD deficiency in 5 ethnic groups (Manggarai, Bajawa, Nage-Keo, Larantuka, and Palue) on the Flores and Palue Islands was lower than that of another native group, Sikka, or a nonnative group, Riung. Molecular analysis of G6PD variants indicated that 19 cases in Sikka had a frequency distribution of G6PD variants similar to those in our previous studies, while 8 cases in Riung had a different frequency distribution of G6PD variants. On the other hand, from field surveys in another 8 ethnic groups (Timorese, Sumbanese, Savunese, Kendari, Buton, Muna, Minahasa, and Sangirese) on the islands of West Timor, Sumba, Sulawesi, Muna and Bangka, a total of 49 deficient cases were detected. Thirty-nine of these 49 cases had G6PD Vanua Lava (383T>C) of Melanesian origin. In our previous studies, many cases of G6PD Vanua Lava were found on other eastern Indonesian islands. Taken together, these findings may indicate that G6PD Vanua Lava is the most common variant in eastern Indonesian populations, except for Sikka. |
Keywords | Glucose-6-phosphate dehydrogenase deficiency rapid G6PD test eastern Indonesian population molecular analysis G6PD Vanua Lava |
Amo Type | Original Article |
Publication Title | Acta Medica Okayama |
Published Date | 2010-12 |
Volume | volume64 |
Issue | issue6 |
Publisher | Okayama University Medical School |
Start Page | 367 |
End Page | 373 |
ISSN | 0386-300X |
NCID | AA00508441 |
Content Type | Journal Article |
language | English |
Copyright Holders | Okayama University Medical School |
File Version | publisher |
Refereed | True |
PubMed ID | 21173806 |
Web of Science KeyUT | 000285664200003 |
Author | Fujioka, Yukio| Fukui, Tetsuya| Kobayashi, Toshiyuki| |
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Published Date | 1959-10-30 |
Publication Title | 岡山医学会雑誌 |
Volume | volume71 |
Issue | issue11-2 |
Content Type | Journal Article |
Author | Tokiya, Tatsuo| |
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Published Date | 1959-10-30 |
Publication Title | 岡山医学会雑誌 |
Volume | volume71 |
Issue | issue11-2 |
Content Type | Journal Article |
Author | Murashima, Fusao| |
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Published Date | 1959-10-30 |
Publication Title | 岡山医学会雑誌 |
Volume | volume71 |
Issue | issue11-2 |
Content Type | Journal Article |
Author | Izumi, Masaaki| |
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Published Date | 1959-09-20 |
Publication Title | 岡山医学会雑誌 |
Volume | volume71 |
Issue | issue10-1 |
Content Type | Journal Article |
Author | Kuroda, Akio| Jinzenji, Kei| Yamamoto, Takashi| Kondo, Kazuji| Shoda, Junzo| |
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Published Date | 1959-09-20 |
Publication Title | 岡山医学会雑誌 |
Volume | volume71 |
Issue | issue10-1 |
Content Type | Journal Article |
Author | Matsui, Toshiyuki| |
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Published Date | 1959-09-10 |
Publication Title | 岡山医学会雑誌 |
Volume | volume71 |
Issue | issue9-2 |
Content Type | Journal Article |
Author | Sakurai, Yasuo| |
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Published Date | 1959-09-10 |
Publication Title | 岡山医学会雑誌 |
Volume | volume71 |
Issue | issue9-2 |
Content Type | Journal Article |
Author | Uématsu, Yoshinori| |
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Published Date | 1959-09-10 |
Publication Title | 岡山医学会雑誌 |
Volume | volume71 |
Issue | issue9-2 |
Content Type | Journal Article |
Author | Shiraishi, Yoshio| |
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Published Date | 1959-09-10 |
Publication Title | 岡山医学会雑誌 |
Volume | volume71 |
Issue | issue9-2 |
Content Type | Journal Article |
Author | Naito, Takakazu| |
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Published Date | 1959-08-15 |
Publication Title | 岡山医学会雑誌 |
Volume | volume71 |
Issue | issue8-2 |
Content Type | Journal Article |
Author | Nagamatsu, Hiroshi| |
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Published Date | 1959-08-15 |
Publication Title | 岡山医学会雑誌 |
Volume | volume71 |
Issue | issue8-2 |
Content Type | Journal Article |
Author | Mitsufuji, Yasuteru| |
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Published Date | 1959-08-10 |
Publication Title | 岡山医学会雑誌 |
Volume | volume71 |
Issue | issue8-1 |
Content Type | Journal Article |
Author | Okajima, Kunio| |
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Published Date | 1959-07-10 |
Publication Title | 岡山医学会雑誌 |
Volume | volume71 |
Issue | issue7-2 |
Content Type | Journal Article |
Author | Mitsufuji, Yasuteru| |
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Published Date | 1959-07-10 |
Publication Title | 岡山医学会雑誌 |
Volume | volume71 |
Issue | issue7-2 |
Content Type | Journal Article |
Author | Nakayama, Akitoshi| |
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Published Date | 1959-06-30 |
Publication Title | 岡山医学会雑誌 |
Volume | volume71 |
Issue | issue7-1 |
Content Type | Journal Article |
Author | Okumura, Kazutoshi| |
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Published Date | 1959-06-30 |
Publication Title | 岡山医学会雑誌 |
Volume | volume71 |
Issue | issue7-1 |
Content Type | Journal Article |