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JaLCDOI 10.18926/21330
Title Alternative The Effect of A Single Bath in Radioactive Hot Spring Water on Variability in Electrocardiograms of Patients with Internal Diseases (1) Repeat Variability in Electrocardiograms of the 100 Patients without Bathing
FullText URL pitsr_033_029_038.pdf
Author Kitayama, Minoru| Kawada, Yoshiro|
Abstract The authors studied time-to-time variability of 100 patients with internal diseases in 100 ECG's over a period of 15 minutes. The variavirity were observed on eleven electrocardiographic items which were measured in 12 leads (I~III, (a)V(R)~(a)V(F), V(1~6)). The electrocardiograms were recorded by same technician, who carefully recorded in confomity to the description on the variability due to techinical and biologocal sources in Simonson's writing and were measured by one of the authors. Frequency distribution of differences between each two electrocardiograms of the same patients are shown in Figures (from 1 to 11) and 5% rejection limits of these differences, which were calculated in use of the stochastics, were as follows : P duration (sec. ) : + 0.022 >X(0)> - 0.021 P-Q duration (sec.) : + 0.029 >X(0)> - 0.024 QRS duration (sec.) : + 0.018 > X(0)> - 0.013 R-R interval (sec.) : + 0.168 >X(0)> - 0.141 QT Ratio (%) + 10.01 >X(0)> - 7.89 QT(c) : + 0.032 >X(0)> - 0.022 P/PR segment : + 0.914 >X(0)> - 0.832 QT/TQ + 0.192 >X(0)> - 0.190 T/R V(5) : + 0.116 >X(0)> - 0.090 AQRS (front. plane) : + 13. 29°>X(0)> - 13.83° AT (front. Plane) : + 14.88°>X(0)> - 16.94°
Publication Title 岡山大学温泉研究所報告
Published Date 1964-03-25
Volume volume33
Start Page 29
End Page 38
ISSN 0369-7142
language Japanese
File Version publisher
NAID 120002311006
JaLCDOI 10.18926/21178
Title Alternative Determination of copper and zinc in synovial fluid by atomic absorption spectrophotometry
FullText URL pitsr_048_013_023.pdf
Author Furuno, Katsushi|
Abstract Copper (Cu) and zinc (Zn) in synovial fluids of 52 patients with rheumatoid arthritis (RA) and of 53 patients with osteoarthritis (OA) were determined using a HITACHI MODEL 207 atomic absorption spectrophotometer. Standard solution of Cu and Zn were 50μg, 100μg, 200μg and 300μg per 100 ml 20 v/v % glycerine containing 0.01 N-HCl. To 0.5ml synovial fluid, 50 units of hyaluronidase was added and then the mixture were incubated for 20 minutes at 37℃. Synovial fluid treated with hyaluronidase and standard solution of Cu and Zn were diluted five fold with deionized distillation water, then aspirated directly into the burner. The relative absorbance was expressed as scale reading by a HITACHI MODEL QPD-54 recoder. The mean recovery rate of Cu and Zn in synovial fluids were 102.0% and 101.9%. By this method the concentrations of Cu and Zn in 52 RA (12 males, 40 females) were 97.6±29.0 (S.D.) μg/100 ml and 83.9±40.1 (S.D.) μg/100 ml ; 97.3±27.1 (S.D.)μg/100 ml, 78.7±29.9 (S.D.) μg /100 ml in 12males and 97.7±29.5 (S.D.) μg/100 ml, 85.5±42.6 (S.D.) μg /100 ml in 40 females respectively. The concentrations of Cu and Zn in 53 OA (14 males, 39 females) were 46.9±14.5 (S.D.) μg/100 ml and 40.8±14.3 (S.D.) μg/100 ml; 47.3±9.7 (S.D.) JLg/100 ml, 45.1±19.0 (S.D.) μg/ 100 ml in 14 males and 46.8±15.8 (S.D.) μg/100 ml, 39.3±11.8 (S.D.) μg/100 ml in 39 females respectively. No sex differences of Cu and Zn values were observed in both RA and OA. In patients with RA, concentrations of Cu and Zn in synovial fluids were signifcantly higher than in OA in both sexes. There were positive correlation between the concentrations of Cu and Zn in 105 patients (RA and OA, r=0.74, p<0.01) , in 52 RA (r=0.54, p<0.01), in 53 OA (r=0.81, p<0.01). In patients with RA, there were no correlation between stage and concentrations of Cu and Zn in synovial fluids.
Publication Title 岡山大学温泉研究所報告
Published Date 1979-03-25
Volume volume48
Start Page 13
End Page 23
ISSN 0369-7142
language Japanese
File Version publisher
NAID 120002311026
JaLCDOI 10.18926/21160
Title Alternative The determination of uric acid using modified Patel's method
FullText URL pitsr_050_025_031.pdf
Author Nishimura, Yoshiko| Aoki, Hiroko| Mifune, Masaaki|
Abstract N 13-b method for determination of uric acid by AutoAnalyzer- I was proposed from Technicon Corporation, but the sensitivity of this method was insufficient. According to the modification by Patel, good sensitivity was obtained for determining of uric acid, but insufficient separation between peaks was accompanied. To get good separation, Patel's method was reexamined by the authors, and the results were as follows. Sufficient separation was obtained by modifing the flow diagram of Patel's method. The mean recovery rates of uric acid added to serum and urine were 103.6% and 102.5%, and coefficients of variation were 1.27% and 1.05% respectively. The correlation between this modified Patel's method and the U.A. test Wako method was recognized (serum : n=95, r=0.97, urine : n=35, r =0.99). According to our modified method, uric acid concentration in serum of 68 subjects, were 5.8±0.9mg/100ml in 29 males and 4.4±0.8mg/100ml in 39 females.
Publication Title 岡山大学温泉研究所報告
Published Date 1980-03-25
Volume volume50
Start Page 25
End Page 31
ISSN 0369-7142
language Japanese
File Version publisher
NAID 120002310944
JaLCDOI 10.18926/21158
Title Alternative Experimental study of sulfur isotope exchange between S0(4)(2-) and H(2)S (aqueous) at 400℃ and 1000 bars water pressure
FullText URL pitsr_050_001_015.pdf
Author Kamada, Emi| Sakai, Hitoshi| Kishima, Noriaki|
Abstract Experimental procedures used in this study are the same as those developed by Sakai and Dickson (1978). 0.005 M Na(2)S(2)O(3) solutions were heated to 400℃ under 1000 bar water pressure in a gold bag of Dickson gold-bag equipment (Fig. 1). At an elevated temperature Na(2)S(2)O(3) quickly and completely decomposed into 1:1 mixture of SO(4)(2-) and H(2)S (eq. (1)) and subsequent isotope exchange (eq. (2)) was monitored by consecutively withdrawing aliquots of solution for chemical and isotopic analyses at desired time intervals. For the preparation of SO(2) for isotope analyses, 2 to 5 mg BaSO(4) was thoroughly mixed with silica glass powder of 10 times the BaSO(4) in weight and heated to 1400℃ or so in sealed, evacuated silica glass tubings (see Fig. 2 and equation (4)). The technique is a modification of Holt and Engelkemeir (1971). The (18)O/(16)O ratios of SO(2) thus formed stayed constant by exchange with silica glass powder (Fig. 3). Numerical data of the three runs performed in this study are summarized in Tables 1 to 3. In runs 2 and 3, a small aliquot of (34)S- enriched H(2)SO(4) was added into the starting solution and thus equilibrium was approached from above the quilibrium value (see Fig. 4). When isotope exchange occurs between two molecules, X and Y, the reaction rate, r, is related to the extent of exchange, F, at given time, t, by equation (17), where X and Y indicate concentrations of given species, α(e), α(o) and α denote the fractionation factor at equilibrium, at time t=0 and at an arbitrary time t, and F = (α - α(o))/(α(e) - α(0)) or the extent of isotope exchange. Assuming the exchange rate is of the first order with respect to both X and Y and to the β'th power of hydrogen ion activity, a(H)(+), eq. (17) reduces to eq. (19), where k(1) denotes the rate constant. If X, Y and pH of solution stayed constant during the run, the half-time, t(1/2), of the exchange reaction can be obtained graphically as shown in Fig. 5. The t(1/2) for runs 1, 2, and 3 are determined to be 5.8, 5.5 and 6.1 hrs, respectively. Introducing F=0.5 and t=t(1/2) into eq. (19), we obtain eq. (20) which is graphically shown in Fig. 6 using the data by the present work and those by Sakai and Dickson(1978). The numerical values of log k(1) + 0.16 may be obtained by extrapolating the lines to pH=0 and, from these values, the rate constant, k(1) , may be calculated for temperatures of 300° and 400℃. From these two values of k(1) and from the Arrhenius plot, the activation energy of the exchange reaction was calculated to be 22 kcal/mole, a much smaller value than 55 kcal/mole obtained by Igumnov (1977). The value of β is found to be 0.29 at 300℃ and 0.075 at 400℃, although the physico-chemical nature of β is not clear to the present authors. Using these values, eq. (24), where C is a constant, is derived which would enable us to calculate the t(1/2) of any system of known ΣS and pH. However, as we do not know yet how β varies with different systems, eq. (24) is applicable only to limited systems in which temperature, total sulfur contents and pH are similar to those of the present study. Fig. 7 illustrates how t(1/2) varies with pH and total sulfur content at 300° and 400℃ and predicts t(1/2) for some solutions obtainable by hydrothermal reactions of seawater with various igneous rocks. The average equilibrium fractionation factor at 400℃ obtained by this study is 1.0153, in good accord with 1.0151 given by Igumnov et al. (1977). Theoretical fractionation factors between SO(4)(2-) and H(2)S have been calculated by Sakai (1968) , who gives too high values compared to the experimental data obtained by this and other researchers (Fig. 9). In the present study, the reduced partition function ratio (R.P.F.R.) of SO(4)(2-) was recalculated using two sets of the vibrational frequencies of SO(4)(2-) (shown in Table 5) and the valence force fields of Heath and Linnett (1947), which reproduces the observed frequencies of SO(4)(2-) better than Urey-Bradley force field used by Sakai (1968). The results of new calculation are shown in Table 6. This table also includes the R.P.F.R. of H(2)S which was calculated by Thode et al. (1971). Using these new R.P.F.R. of SO(4)(2-) and H(2)S, the fractionation factors between SO(4)(2-) and H(2)S were calculated and are listed in the last column of Table 6 and plotted in Fig. 9. Fig. 9 indicates that the new calculation gives values more shifted from the experimental values than before. The major sulfate ions in our solution at 300° and 400℃ exist as NaSO(4)(-) (Sakai and Dickson, 1978; see also Table 4 of this paper) and, therefore, the measured fractionation factors are those between NaSO(4)(-) and H(2)S. The discrepancy between the theory and experiments may, at least, be partially explained by this fact, although other more important reasons, which are not known to us at the moment, may also exist.
Publication Title 岡山大学温泉研究所報告
Published Date 1980-03-25
Volume volume50
Start Page 1
End Page 15
ISSN 0369-7142
language Japanese
File Version publisher
NAID 120002310990
JaLCDOI 10.18926/21114
Title Alternative Determination of ferritin in serum and in synovial fluids of patients with rheumatoid arthritis
FullText URL pitsr_053_001_008.pdf
Author Furuno, Katsushi| Morinaga, Hiroshi| Irino, Shozo|
Abstract Ferritin in sera and in synovial fluids were determined by method of immunoradiometric assay (IRMA) and of radioimmunoassay (RIA). These methods have been proved to be reproducible. The coefficient variation was 7.4 to 9.9% in IRMA and 5.6 to 8.0% in RIA. There were a good correlation between methods of IRMA and of RIA (r=0.989). The mean recovery rate of ferritin in serum was 101.2% in IRMA and 101.0% in RIA, respectively. The determination of serum ferritin revealed a 16% reduction in average after preservation at -20℃ during over 100 days. The levels of serum ferritin in healthy controls were 131.4±52.1 ng/ml in 34 males and 58.4±39.9 ng/ml in 38 females. The sex differences were statisticalIy significant (p<0.01). Ferritin levels were shown to be below 30 ng/ml (the state of iron deficiency) in 2 of 34 (5.9%) males and in 8 of 38 (21%) females of healthy controls. The levels of serum ferritin in patients with rheumatoid arthritis (RA) were 337.0±293.4ng/ml in 10 males and 181.4±329.9ng/ml in 25 females. The serum ferritin in RA was significantly higher than in healthy controls of both sexes. The levels of ferritin in synovial fluids of patients with 14 RA and with 12 osteoarthritis were 2894±3017 ng/ml and 1429±1005 ng/ml, and no differences were observed in both groups.
Publication Title 岡山大学温泉研究所報告
Published Date 1983-03-25
Volume volume53
Start Page 1
End Page 8
ISSN 0369-7142
language Japanese
File Version publisher
NAID 120002311016
Author Tanaka, Masato| Sugimoto, Yoshihisa| Misawa, Haruo| Takahata, Tomohiro| Ozaki, Toshifumi|
Published Date 2010-04-01
Publication Title 岡山医学会雑誌
Volume volume122
Issue issue1
Content Type Journal Article
Author Hamano, Ryosuke| Inagaki, Masaru| Nishie, Manabu| Tokunaga, Naoyuki| Tsunemitsu, Yosuke| Ohtsuka, Shinya| Iwakawa, Kazuhide| Iwagaki, Hiromi| Sonobe, Hiroshi|
Published Date 2010-04-01
Publication Title 岡山医学会雑誌
Volume volume122
Issue issue1
Content Type Journal Article
Author Namba, Masayoshi|
Published Date 2010-04-01
Publication Title 岡山医学会雑誌
Volume volume122
Issue issue1
Content Type Journal Article
Author Otani, Hiroyuki| Otsuka, Fumio| Makino, Hirofumi|
Published Date 2010-04-01
Publication Title 岡山医学会雑誌
Volume volume122
Issue issue1
Content Type Journal Article
Author Watanabe, Nobuyuki| Takaoka, Munenori| Sakurama, Kazufumi| Tomono, Yasuko| Hatakeyama, Shinji| Ohmori, Osamu| Motoki, Takayuki| Shirakawa, Yasuhiro| Yamatsuji, Tomoki| Haisa, Minoru| Matsuoka, Junji| Beer, David G.| Nagatsuka, Hitoshi| Tanaka, Noriaki| Naomoto, Yoshio|
Published Date 2010-04-01
Publication Title 岡山医学会雑誌
Volume volume122
Issue issue1
Content Type Journal Article
Author Ariumi, Yasuo| Kuroki, Misao| Dansako, Hiromichi| Abe, Kenichi| Ikeda, Masanori| Wakita, Takaji| Kato, Nobuyuki|
Published Date 2010-04-01
Publication Title 岡山医学会雑誌
Volume volume122
Issue issue1
Content Type Journal Article
Author Yasuhara, Akihiro| Wada, Jun| Eguchi, Jun| Nakatsuka, Atsuko| Murakami, Kazutoshi| Kanzaki, Motoko| Teshigawara, Sanae| Makino, Hirofumi|
Published Date 2010-04-01
Publication Title 岡山医学会雑誌
Volume volume122
Issue issue1
Content Type Journal Article
Author Miyasako, Nobuyoshi| Takatsuka, Shigenobu|
Published Date 2005-12
Publication Title 日本教科教育学会誌
Volume volume28
Issue issue3
Content Type Journal Article
Author Yamamoto, Koichi| Motomizu, Shoji|
Published Date 1989-04-10
Publication Title Analytical Sciences
Volume volume5
Issue issue2
Content Type Journal Article
JaLCDOI 10.18926/19960
FullText URL Mem_Fac_Eng_OU_44_60.pdf
Author Nogami, Yasuyuki| Morikawa, Yoshitaka|
Abstract This paper proposes a method for generating a certain composite order ordinary pairing–friendly elliptic curve of embedding degree 3. In detail, the order has two large prime factors such as the modulus of RSA cryptography. The method is based on the property that the order of the target pairing–friendly curve is given by a polynomial as r(X) of degree 2 with respect to the integer variable X. When the bit size of the prime factors is about 500 bits, the proposed method averagely takes about 15 minutes on Core 2 Quad (2.66Hz) for generating one.
Publication Title Memoirs of the Faculty of Engineering, Okayama University
Published Date 2010-01
Volume volume44
Start Page 60
End Page 68
ISSN 1349-6115
language English
File Version publisher
NAID 120002309063
Author Motomizu, Shoji| Hamada, Shoichi| Toei, Kyoji|
Published Date 1983-11-05
Publication Title 分析化学
Volume volume32
Issue issue11
Content Type Journal Article
Author Motomizu, Shoji| Hosoi, Yasuhiro| Oshima, Mitsuko|
Published Date 1990-04-05
Publication Title 分析化学
Volume volume39
Issue issue4
Content Type Journal Article
Author Motomizu, Shoji| Kuwabara, Masayosi| Oshima, Mitsuko|
Published Date 1994-08-05
Publication Title 分析化学
Volume volume43
Issue issue8
Content Type Journal Article
Author Hirose, Atsushi|
Published Date 1956-11-30
Publication Title 岡山医学会雑誌
Volume volume68
Issue issue11
Content Type Journal Article
Author Hirose, Atsushi|
Published Date 1956-11-30
Publication Title 岡山医学会雑誌
Volume volume68
Issue issue11
Content Type Journal Article