result 47822 件
| JaLCDOI | 10.18926/AMO/49669 |
|---|---|
| FullText URL | 67_2_105.pdf |
| Author | Alafate, Aierken| Shinya, Takayoshi| Okumura, Yoshihiro| Sato, Shuhei| Hiraki, Takao| Ishii, Hiroaki| Gobara, Hideo| Kato, Katsuya| Fujiwara, Toshiyoshi| Miyoshi, Shinichiro| Kaji, Mitsumasa| Kanazawa, Susumu| |
| Abstract | We retrospectively evaluated the accumulation of fluorodeoxy glucose (FDG) in pulmonary malignancies without local recurrence during 2-year follow-up on positron emission tomography (PET)/computed tomography (CT) after radiofrequency ablation (RFA). Thirty tumors in 25 patients were studied (10 non-small cell lung cancers;20 pulmonary metastatic tumors). PET/CT was performed before RFA, 3 months after RFA, and 6 months after RFA. We assessed the FDG accumulation with the maximum standardized uptake value (SUVmax) compared with the diameters of the lesions. The SUVmax had a decreasing tendency in the first 6 months and, at 6 months post-ablation, FDG accumulation was less affected by inflammatory changes than at 3 months post-RFA. The diameter of the ablated lesion exceeded that of the initial tumor at 3 months post-RFA and shrank to pre-ablation dimensions by 6 months post-RFA. SUVmax was more reliable than the size measurements by CT in the first 6 months after RFA, and PET/CT at 6 months post-RFA may be more appropriate for the assessment of FDG accumulation than that at 3 months post-RFA. |
| Keywords | fluorodeoxy glucose (FDG) positron emission tomography (PET) standardized uptake value (SUV) radiofrequency ablation (RFA) non-small cell lung cancer (NSCLC) |
| Amo Type | Original Article |
| Publication Title | Acta Medica Okayama |
| Published Date | 2013-04 |
| Volume | volume67 |
| Issue | issue2 |
| Publisher | Okayama University Medical School |
| Start Page | 105 |
| End Page | 112 |
| ISSN | 0386-300X |
| NCID | AA00508441 |
| Content Type | Journal Article |
| language | English |
| Copyright Holders | CopyrightⒸ 2013 by Okayama University Medical School |
| File Version | publisher |
| Refereed | True |
| PubMed ID | 23603927 |
| Web of Science KeyUT | 000317801700005 |
| Related Url | http://ousar.lib.okayama-u.ac.jp/metadata/50688 |
| JaLCDOI | 10.18926/AMO/49668 |
|---|---|
| FullText URL | 67_2_99.pdf |
| Author | Mikawa, Yasuhito| Mizobuchi, Satoshi| Egi, Moritoki| Morita, Kiyoshi| |
| Abstract | Patients undergoing a panic attack (PA) or a hyperventilation attack (HVA) are sometimes admitted to emergency departments (EDs). Reduced serotonin level is known as one of the causes of PA and HVA. Serotonin is synthesized from tryptophan. For the synthesis of serotonin, vitamin B6 (Vit B6) and iron play important roles as cofactors. To clarify the pathophysiology of PA and HVA, we investigated the serum levels of vitamins B2, B6, and B12 and iron in patients with PA or HVA attending an ED. We measured each parameter in 21 PA or HVA patients and compared the values with those from 20 volunteers. We found that both Vit B6 and iron levels were significantly lower in the PA/HVA group than in the volunteer group. There was no significant difference in the serum levels of vitamins B2 or B12. These results suggest that low serum concentrations of Vit B6 and iron are involved in PA and HVA. Further studies are needed to clarify the mechanisms involved in such differences. |
| Keywords | panic hyperventilation vitamin B6 iron serotonin |
| Amo Type | Original Article |
| Publication Title | Acta Medica Okayama |
| Published Date | 2013-04 |
| Volume | volume67 |
| Issue | issue2 |
| Publisher | Okayama University Medical School |
| Start Page | 99 |
| End Page | 104 |
| ISSN | 0386-300X |
| NCID | AA00508441 |
| Content Type | Journal Article |
| language | English |
| Copyright Holders | CopyrightⒸ 2013 by Okayama University Medical School |
| File Version | publisher |
| Refereed | True |
| PubMed ID | 23603926 |
| Web of Science KeyUT | 000317801700004 |
| Related Url | http://ousar.lib.okayama-u.ac.jp/metadata/50643 |
| JaLCDOI | 10.18926/AMO/49667 |
|---|---|
| FullText URL | 67_2_93.pdf |
| Author | Kita, Masahide| Yokota, Kenji| Okada, Hiroyuki| Take, Susumu| Takenaka, Ryuta| Kawahara, Yoshiro| Oguma, Keiji| Matsushita, Osamu| Yamamoto, Kazuhide| |
| Abstract | Atrophy of the gastric mucosa is a precursor of intestinal-type gastric cancer, and Helicobacter pylori infection causes atrophic gastritis. The aim of this study was to determine whether the genetic diversity of H. pylori virulence genes is associated with the development and progression of gastric atrophy in humans. We isolated and cultured H. pylori strains from patients with gastric ulcer and duodenal ulcer accompanied by atrophic gastritis in background mucosa. H. pylori strains were stored at －80℃ prior to the experiments being carried out. We analyzed iceA, babA, vacA, cagA, and cagE genes by PCR. The cagA gene was analyzed through sequencing of the C-terminal region containing the EPIYA motif, which is related to tyrosine phosphorylation. Severe atrophy was observed in patients with gastric ulcer. The major phenotype of the vacA gene was s1c/m1 (93ｵ). The cagA gene was detected in all strains. The cagE gene was not detected in 2 and 5 strains from the mild cases and severe cases, respectively. The major cagA EPIYA motif, which is amino acids repeat in the C terminus, was the A-B-D type (44 of 58 strains). The virulence genes were not statistically associated with the severity of atrophy in the background gastric mucosa in humans. Not only identification of bacterial virulence factors but also studies of the host response will be necessary to investigate the progression of gastric atrophy and subsequent cancer development in humans. |
| Keywords | Helicobacter pylori virulence genes chronic atrophic gastritis |
| Amo Type | Original Article |
| Publication Title | Acta Medica Okayama |
| Published Date | 2013-04 |
| Volume | volume67 |
| Issue | issue2 |
| Publisher | Okayama University Medical School |
| Start Page | 93 |
| End Page | 98 |
| ISSN | 0386-300X |
| NCID | AA00508441 |
| Content Type | Journal Article |
| language | English |
| Copyright Holders | CopyrightⒸ 2013 by Okayama University Medical School |
| File Version | publisher |
| Refereed | True |
| PubMed ID | 23603925 |
| Web of Science KeyUT | 000317801700003 |
| Related Url | http://ousar.lib.okayama-u.ac.jp/metadata/52508 |
| JaLCDOI | 10.18926/AMO/49666 |
|---|---|
| FullText URL | 67_2_87.pdf |
| Author | Matsuo, Toshihiko| Takeda, Yoshimasa| Ohtsuka, Aiji| |
| Abstract | The purpose of this study was to develop a series of stereoscopic anatomical images of the eye and orbit for use in the curricula of medical schools and residency programs in ophthalmology and other specialties. Layer-by-layer dissection of the eyelid, eyeball, and orbit of a cadaver was performed by an ophthalmologist. A stereoscopic camera system was used to capture a series of anatomical views that were scanned in a panoramic three-dimensional manner around the center of the lid fissure. The images could be rotated 360 degrees in the frontal plane and the angle of views could be tilted up to 90 degrees along the anteroposterior axis perpendicular to the frontal plane around the 360 degrees. The skin, orbicularis oculi muscle, and upper and lower tarsus were sequentially observed. The upper and lower eyelids were removed to expose the bulbar conjunctiva and to insert three 25-gauge trocars for vitrectomy at the location of the pars plana. The cornea was cut at the limbus, and the lens with mature cataract was dislocated. The sclera was cut to observe the trocars from inside the eyeball. The sclera was further cut to visualize the superior oblique muscle with the trochlea and the inferior oblique muscle. The eyeball was dissected completely to observe the optic nerve and the ophthalmic artery. The thin bones of the medial and inferior orbital wall were cracked with a forceps to expose the ethmoid and maxillary sinus, respectively. In conclusion, the serial dissection images visualized aspects of the local anatomy specific to various procedures, including the levator muscle and tarsus for blepharoptosis surgery, 25-gauge trocars as viewed from inside the eye globe for vitrectomy, the oblique muscles for strabismus surgery, and the thin medial and inferior orbital bony walls for orbital bone fractures. |
| Keywords | stereoscopic camera-captured images education local anatomical dissection orbit eye |
| Amo Type | Original Article |
| Publication Title | Acta Medica Okayama |
| Published Date | 2013-04 |
| Volume | volume67 |
| Issue | issue2 |
| Publisher | Okayama University Medical School |
| Start Page | 87 |
| End Page | 91 |
| ISSN | 0386-300X |
| NCID | AA00508441 |
| Content Type | Journal Article |
| language | English |
| Copyright Holders | CopyrightⒸ 2013 by Okayama University Medical School |
| File Version | publisher |
| Refereed | True |
| PubMed ID | 23603924 |
| Web of Science KeyUT | 000317801700002 |
| JaLCDOI | 10.18926/AMO/49665 |
|---|---|
| FullText URL | 67_2_75.pdf |
| Author | Otsuka, Fumio| |
| Abstract | New biological activities of bone morphogenetic proteins (BMPs) in the endocrine system have recently been revealed. The BMP system is composed of approximately 30 ligands and preferential combinations of type I and type II receptors. The BMP system not only induces bone formation but also plays unique tissue-specific roles in various organs. For instance, the ovarian BMP system is a physiological inhibitor of luteinization in growing ovarian follicles. In the ovary, the expression of oocyte-derived BMP-15 is critical for female reproduction. In the pituitary, BMP-4 is a key player for initial development of the anterior pituitary, while it is also functionally involved in some differentiated pituitary tumors, including prolactinoma and Cushingʼs disease. In the adrenal glands, BMP-6 and BMP-4 modulate aldosterone and catecholamine production, respectively, which contributes to a functional interaction between the cortex and medulla. In the present review, recent advances in BMP biology in the field of endocrinology are described and the possibility for clinical application of BMP activity is discussed. |
| Keywords | bone morphogenetic protein folliculogenesis pituitary adenoma steroidogenesis transforming growth factor |
| Amo Type | Review |
| Publication Title | Acta Medica Okayama |
| Published Date | 2013-04 |
| Volume | volume67 |
| Issue | issue2 |
| Publisher | Okayama University Medical School |
| Start Page | 75 |
| End Page | 86 |
| ISSN | 0386-300X |
| NCID | AA00508441 |
| Content Type | Journal Article |
| language | English |
| Copyright Holders | CopyrightⒸ 2013 by Okayama University Medical School |
| File Version | publisher |
| Refereed | True |
| PubMed ID | 23603923 |
| Web of Science KeyUT | 000317801700001 |
| Author | Itano, Arao| Arakawa, Satiyo| |
|---|---|
| Published Date | 1928-01-26 |
| Publication Title | Berichte des Ohara Instituts für landwirtschaftliche Forschungen |
| Volume | volume3 |
| Issue | issue5 |
| Content Type | Departmental Bulletin Paper |
| Author | Itano, Arao| Arakawa, Satiyo| |
|---|---|
| Published Date | 1927-10-26 |
| Publication Title | Berichte des Ohara Instituts für landwirtschaftliche Forschungen |
| Volume | volume3 |
| Issue | issue5 |
| Content Type | Departmental Bulletin Paper |
| Author | Kondō, Mantarō| |
|---|---|
| Published Date | 1927-12-01 |
| Publication Title | Berichte des Ohara Instituts für landwirtschaftliche Forschungen |
| Volume | volume3 |
| Issue | issue5 |
| Content Type | Departmental Bulletin Paper |
| Author | Kondō, Mantarō| |
|---|---|
| Published Date | 1927-07-25 |
| Publication Title | Berichte des Ohara Instituts für landwirtschaftliche Forschungen |
| Volume | volume3 |
| Issue | issue4 |
| Content Type | Departmental Bulletin Paper |
| Author | Kondō, Mantarō| Fujimoto, Sumita| |
|---|---|
| Published Date | 1927-05-20 |
| Publication Title | Berichte des Ohara Instituts für landwirtschaftliche Forschungen |
| Volume | volume3 |
| Issue | issue4 |
| Content Type | Departmental Bulletin Paper |
| Author | Kondō, Mantarō| Okamura, Tamotsu| |
|---|---|
| Published Date | 1927-01-06 |
| Publication Title | Berichte des Ohara Instituts für landwirtschaftliche Forschungen |
| Volume | volume3 |
| Issue | issue4 |
| Content Type | Departmental Bulletin Paper |
| Author | Harukawa, Chukichi| |
|---|---|
| Published Date | 1927-02-28 |
| Publication Title | Berichte des Ohara Instituts für landwirtschaftliche Forschungen |
| Volume | volume3 |
| Issue | issue4 |
| Content Type | Departmental Bulletin Paper |
| Author | Nisikado, Yosikazu| |
|---|---|
| Published Date | 1927-02-25 |
| Publication Title | Berichte des Ohara Instituts für landwirtschaftliche Forschungen |
| Volume | volume3 |
| Issue | issue3 |
| Content Type | Departmental Bulletin Paper |
| Author | Itano, A.| Arakawa, S.| Hosoda, K.| |
|---|---|
| Published Date | 1927-02-20 |
| Publication Title | Berichte des Ohara Instituts für landwirtschaftliche Forschungen |
| Volume | volume3 |
| Issue | issue3 |
| Content Type | Departmental Bulletin Paper |
| Author | Itano, Arao| Arakawa, Satiyo| |
|---|---|
| Published Date | 1927-01-10 |
| Publication Title | Berichte des Ohara Instituts für landwirtschaftliche Forschungen |
| Volume | volume3 |
| Issue | issue3 |
| Content Type | Departmental Bulletin Paper |
| Author | Yamaguti, Yasuke| |
|---|---|
| Published Date | 1927-01-15 |
| Publication Title | Berichte des Ohara Instituts für landwirtschaftliche Forschungen |
| Volume | volume3 |
| Issue | issue3 |
| Content Type | Departmental Bulletin Paper |
| Author | Kondō, Mantarō| Takeda, Motoharu| Fujimoto, Sumita| |
|---|---|
| Published Date | 1927-02-05 |
| Publication Title | Berichte des Ohara Instituts für landwirtschaftliche Forschungen |
| Volume | volume3 |
| Issue | issue3 |
| Content Type | Departmental Bulletin Paper |
| Author | Kondō, Mantarō| |
|---|---|
| Published Date | 1927-01-16 |
| Publication Title | Berichte des Ohara Instituts für landwirtschaftliche Forschungen |
| Volume | volume3 |
| Issue | issue3 |
| Content Type | Departmental Bulletin Paper |
| Published Date | 1926 |
|---|---|
| Publication Title | Berichte des Ohara Instituts für landwirtschaftliche Forschungen |
| Volume | volume3 |
| Issue | issue2 |
| Content Type | Departmental Bulletin Paper |
| Author | Nisikado, Yosikazu| Miyake, Chuichi| |
|---|---|
| Published Date | 1926-08-25 |
| Publication Title | Berichte des Ohara Instituts für landwirtschaftliche Forschungen |
| Volume | volume3 |
| Issue | issue2 |
| Content Type | Departmental Bulletin Paper |
