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Author Asonuma, Hirohiko|
Published Date 1989-06
Publication Title 岡山医学会雑誌
Volume volume101
Issue issue5-6
Content Type Journal Article
Author Sumii, Hiroshi| Inoue, Hajime| Ito, Shiro| Tanabe, Gozo| Takechi, Hideo| Ikeda, Shogo| Oda, Takuzo|
Published Date 1989-04
Publication Title 岡山医学会雑誌
Volume volume101
Issue issue3-4
Content Type Journal Article
Author Kusaka, Yasunori| Tokiwa, Takayoshi| Sato, Jiro| Tsuge, Hiroshi| Hamasaki, Keisuke| Mimura, Hisashi| Orita, Kunzo|
Published Date 1989-02
Publication Title 岡山医学会雑誌
Volume volume101
Issue issue1-2
Content Type Journal Article
Author Tomida, Osamu|
Published Date 1989-02
Publication Title 岡山医学会雑誌
Volume volume101
Issue issue1-2
Content Type Journal Article
Author Tada, Atsuhiko|
Published Date 1990-12
Publication Title 岡山医学会雑誌
Volume volume102
Issue issue11-12
Content Type Journal Article
Author Kobayashi, Youji|
Published Date 1990-12
Publication Title 岡山医学会雑誌
Volume volume102
Issue issue11-12
Content Type Journal Article
Author Nakagawa, Saburo|
Published Date 1990-10
Publication Title 岡山医学会雑誌
Volume volume102
Issue issue9-10
Content Type Journal Article
Author Tamiya, Takashi|
Published Date 1990-10
Publication Title 岡山医学会雑誌
Volume volume102
Issue issue9-10
Content Type Journal Article
Author Endo, Akira|
Published Date 1990-06
Publication Title 岡山医学会雑誌
Volume volume102
Issue issue5-6
Content Type Journal Article
Author Kunikata, Eiji|
Published Date 1990-04
Publication Title 岡山医学会雑誌
Volume volume102
Issue issue3-4
Content Type Journal Article
Author Yanagihara, Shigehiro|
Published Date 2010-03-25
Publication Title
Content Type Thesis or Dissertation
Author Wael, Amgad Refaat Ahmed Hassan|
Published Date 2010-03-25
Content Type Thesis or Dissertation
Author Ohashi, Katsuhisa|
Published Date 2010-03-25
Publication Title
Content Type Thesis or Dissertation
Author Kojima, Toru|
Published Date 2010-03-25
Publication Title
Content Type Thesis or Dissertation
JaLCDOI 10.18926/21119
Title Alternative 好塩基球からのヒスタミン遊離に関する研究. 2. ハウスダスト抗原および抗ヒトIgEによるヒスタミン遊離
FullText URL pitsr_053_029_033.pdf
Author Tanizaki, Yoshiro| Komagoe, Haruki| Sudo, Michiyasu| Mifune, Masaaki| Morinaga, Hiroshi| Kitani, Hikaru| Goda, Yoshinori| Tada, Shinya| Kimura, Ikuro|
Abstract IgE-mediated release of histamine from whole blood was examined in two healthy and four asthmatic subjects by dose-dependent fashion. The significantly increased amount of histamine was released from basophils of both healthy and asthmatic subjects by a limited concentration of anti-IgE. Antigen (house dust) caused histamine release only from basophils of asthmatics who are sensitive to house dust. Basophils from one patients with asthma released no significant amount of histamine by anti-IgE.
Publication Title 岡山大学温泉研究所報告
Published Date 1983-03-25
Volume volume53
Start Page 29
End Page 33
ISSN 0369-7142
language English
File Version publisher
NAID 120002310980
JaLCDOI 10.18926/21118
Title Alternative 好塩基球からのヒスタミン遊離に関する研究. 1 自動分析装置による全血からのヒスタミン遊離の測定
FullText URL pitsr_053_023_028.pdf
Author Tanizaki, Yoshiro| Komagoe, Haruki| Sudo, Michiyasu| Mifune, Masaaki| Morinaga, Hiroshi| Ohtani, Jun| Kitani, Hikaru| Goda, Yoshinori| Tada, Shinya| Kimura, Ikuro|
Abstract Histamine released from whole blood was determined by an automated fiuorometric histamine analysis system. The increased release of histamine from basophils by anti-IgE was observed in ten healthy subjects and 12 extrinsic asthma patients, while the release in 11 intrinsic asthma patients was significantly less as compared to that in healthy and extrinsic asthma subjects. House dust extract caused a significant increase in the histamine release from basophils of the extrinsic asthma patients who are sensitive to house dust. It was concluded from this study that histamine released from basophils could be easily determined by an automated analysis system and that the method is useful for the diagnosis and study of allergy.
Publication Title 岡山大学温泉研究所報告
Published Date 1983-03-25
Volume volume53
Start Page 23
End Page 28
ISSN 0369-7142
language English
File Version publisher
NAID 120002310945
JaLCDOI 10.18926/21106
Title Alternative 好塩基球からのヒスタミン遊離に関する研究. 3. 抗ヒトIgE に対する好塩基球の反応性と末梢血好酸球増多
FullText URL pitsr_054_035_038.pdf
Author Tanizaki, Yoshiro| Komagoe, Haruki| Sudo, Michiyasu| Mifune, Masaaki| Morinaga, Hiroshi| Nakagawa, Saburo| Kitani, Hikaru| Kimura, Ikuro|
Abstract Histamine release from basophils induced by anti-IgE was examined in 14 asthmatic subjects with blood eosinophilia. The subjects were divided into two groups; group I (with blood eosinophilia, positive skin test and positive RAST to house dust) and group II (with blood eosinophilia, negative skin test to various allergens and negative RAST to house dust). 1. Serum IgE levels in group I were much higher than those in group II. 2. Maximum percent histamine release induced by anti-IgE was much higher in group I than in group II. 3. Dose-response curve of anti-IgE-induced histamine release in group I showed consistent increase as anti-IgE concentrations increased. while, dose-response curve in group II was very low. These findings suggested that blood eosinophilia in group I might be elicited relating to IgE-mediated reaction. However, mechanism causing eosinophilia in group II was not clear in the present study.
Publication Title 岡山大学温泉研究所報告
Published Date 1984-03-25
Volume volume54
Start Page 35
End Page 38
ISSN 0369-7142
language English
File Version publisher
NAID 120002310989
JaLCDOI 10.18926/21095
Title Alternative Spa therapy for patients with chronic obstructive lung disease
FullText URL pitsr_055_007_010.pdf
Author Tanizaki, Yoshiro| Komagoe, Haruki| Sudo, Michiyasu| Morinaga, Hiroshi| Kitani, Hikaru| Nakagawa, Saburo| Kimura, Ikuro|
Abstract Histamine releasse from basophils induced by house dust and C. albicans was examined in 30 patients with bronchial asthma. House dust and C. albicans caused a significant amount of histamine release in subjects with a RAST score to corresponding allergen. A close correlation was found between house dust- and anti-IgE-induced histamine release. However, histamine release induced by C. albicans was considerably different from the release induced by anti-IgE.
Publication Title 岡山大学温泉研究所報告
Published Date 1984-11-30
Volume volume55
Start Page 7
End Page 10
ISSN 0369-7142
language English
File Version publisher
NAID 120002310939
JaLCDOI 10.18926/21083
Title Alternative 好塩基球からのヒスタミン遊離に関する研究. 5.臨床的評価
FullText URL pitsr_056_017_021.pdf
Author Tanizaki, Yoshiro| Komagoe, Haruki| Sudo, Michiyasu| Morinaga, Hiroshi|
Abstract 過去3年間にわたり,気管支喘息患者末梢血好塩基球からのヒスタミン遊離について,ヒスタミン自動分析装置を用いて全血法により検討を加えてきた. 1. 抗ヒトIgE によるヒスタミン遊離は,症例間で著しい差がみられた. この際血清IgE値が高値を示す症例では全般的に高度なヒスタシソ遊離がみられたが,血清IgE値が正常かまたはむしろ低値を示す症例のヒスタミン遊離は,かなり高度なものから全くみられないものまでさまざまであった. 2.ハウスダストやカンジダなどの抗原物質によるヒスタミン遊離は,特異的IgE抗体依存性であり,抗体価が上昇するにつれヒスタミン遊離は高度となる傾向がみられた. しかし,ハウスダストとカンジダによるヒスタミン遊離には若干の差がみられた. すなわち,ハウスダストと抗ヒトIgE によるヒスタミン遊離の間には密接な関連がみられたが,カンジダと抗ヒトIgEの間には全く関連がみられなかった. またカンジダによるヒスタミン遊離においては,IgE系反応以外の反応が関与する可能性が一部示唆された.
Publication Title 岡山大学温泉研究所報告
Published Date 1985-03-30
Volume volume56
Start Page 17
End Page 21
ISSN 0369-7142
language English
File Version publisher
NAID 120002310985
Author Hayatsu, Hikoya|
Published Date 1993-06
Publication Title 岡山実験動物研究会報
Volume volume10
Content Type Others