| ID | 69324 |
| FullText URL | |
| Author |
Kondo, Yoshitaka
Department of Gastroenterological Surgery, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences
ORCID
Kaken ID
researchmap
Kanaya, Nobuhiko
Department of Gastroenterological Surgery, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences
Shoji, Ryohei
Department of Gastroenterological Surgery, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences
Inokuchi, Toshihiro
Research Center for Intestinal Health Science, Okayama University
Hiraoka, Sakiko
Department of Gastroenterology and Hepatology, Okayama University Graduate School of Medicine, Dentistry, and Pharmaceutical Sciences
Kaken ID
publons
researchmap
Yoshida, Yusuke
Department of Gastroenterological Surgery, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences
Matsumi, Yuki
Department of Gastroenterological Surgery, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences
Shigeyasu, Kunitoshi
Department of Gastroenterological Surgery, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences
Teraishi, Fuminori
Department of Gastroenterological Surgery, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences
Kuroda, Shinji
Department of Gastroenterological Surgery, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences
ORCID
Kaken ID
researchmap
Fujiwara, Toshiyoshi
Department of Gastroenterological Surgery, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences
ORCID
Kaken ID
publons
researchmap
|
| Abstract | Introduction: Crohn's disease (CD) often leads to complex anorectal complications, posing significant challenges in surgical management. Transperineal abdominoperineal resection (TpAPR) has emerged as a minimally invasive alternative to APR. This study aims to evaluate the safety and efficacy of TpAPR compared to APR in patients with CD.
Methods: A retrospective analysis was conducted on 19 CD patients who underwent either minimally invasive TpAPR (n = 11) or APR (n = 8) between 2008 and 2023 from a single institution. The primary outcomes were assessed: intraoperative blood loss, operative time, and surgical site infection (SSI) rates. Results: The minimally invasive TpAPR group exhibited significantly reduced intraoperative blood loss (223 mL vs. 533 mL, p = 0.04) and a lower incidence of SSI rates (36.4% vs. 75%, p = 0.07). Operative time and hospital stay were comparable between groups. Conclusion: Minimally invasive TpAPR demonstrates potential benefits over APR in reducing blood loss and SSI rates in CD patients. Further large-scale studies are warranted to confirm these findings. |
| Keywords | Crohn's disease
intraoperative blood loss
minimally invasive surgery
surgical site infection (SSI)
transperineal abdominoperineal resection (TpAPR)
|
| Published Date | 2025-01
|
| Publication Title |
Asian Journal of Endoscopic Surgery
|
| Volume | volume18
|
| Issue | issue1
|
| Publisher | Wiley
|
| Start Page | e70149
|
| ISSN | 1758-5902
|
| NCID | AA12488501
|
| Content Type |
Journal Article
|
| language |
English
|
| OAI-PMH Set |
岡山大学
|
| Copyright Holders | © 2025 The Author(s).
|
| File Version | publisher
|
| PubMed ID | |
| DOI | |
| Related Url | isVersionOf https://doi.org/10.1111/ases.70149
|
| License | http://creativecommons.org/licenses/by-nc/4.0/
|
| Citation | Y. Kondo, N. Kanaya, R. Shoji, et al., “ Clinical Impacts of Minimally Invasive Transperineal Abdominoperineal Resection in Crohn's Disease: A Retrospective Analysis,” Asian Journal of Endoscopic Surgery 18, no. 1 (2025): e70149, https://doi.org/10.1111/ases.70149.
|
| 助成情報 |
24K11823:
クローン病における細胞老化関連分泌形質SASPのRNA編集促進機構の解明と治療への応用
( 独立行政法人日本学術振興会 / Japan Society for the Promotion of Science )
|
