A Case of Mediastinal Localized Malignant Pleural Mesothelioma Successfully Treated by Chemotherapy and Conversion Surgery

Maki, Yuho; Kiriyama, Yosuke; Ueno, Tsuyoshi; Suehisa, Hiroshi; Shigematsu, Hisayuki; Saeki, Kazuhiko; Harada, Daijiro; Kozuki, Toshiyuki; Teramoto, Norihiro; Yamashita, Motohiro

ID	63746
JaLCDOI	10.18926/AMO/63746
FullText URL	76_3_343.pdf 4.99 MB
Author	Maki, Yuho Department of Thoracic Surgery, National Hospital Organization Shikoku Cancer Center Kiriyama, Yosuke Department of Thoracic Surgery, National Hospital Organization Shikoku Cancer Center Ueno, Tsuyoshi Department of Thoracic Surgery, National Hospital Organization Shikoku Cancer Center Suehisa, Hiroshi Department of Thoracic Surgery, National Hospital Organization Shikoku Cancer Center Shigematsu, Hisayuki Department of Thoracic Surgery, National Hospital Organization Shikoku Cancer Center Saeki, Kazuhiko Department of Thoracic Oncology and Medicine, National Hospital Organization Shikoku Cancer Center Harada, Daijiro Department of Thoracic Oncology and Medicine, National Hospital Organization Shikoku Cancer Center Kozuki, Toshiyuki Department of Thoracic Oncology and Medicine, National Hospital Organization Shikoku Cancer Center Teramoto, Norihiro Department of Pathology, National Hospital Organization Shikoku Cancer Center Yamashita, Motohiro Department of Thoracic Surgery, National Hospital Organization Shikoku Cancer Center
Abstract	Localized malignant mesothelioma is a rare disease and little is known about its treatment strategy. We herein report a case of localized malignant pleural mesothelioma that had infiltrated into the anterior mediastinum, which was successfully treated using chemotherapy and conversion surgery. A 63-year-old man with a mediastinal tumor was referred to our hospital. Pathologic analysis of the biopsy specimen showed malignant mesothelioma. Significant tumor shrinkage by cisplatin and pemetrexed was observed and he underwent radical surgery via a median sternotomy. The patient has been disease free for 12 months.
Keywords	localized mesothelioma mediastinum cisplatin pemetrexed conversion surgery
Amo Type	Case Report
Publication Title	Acta Medica Okayama
Published Date	2022-06
Volume	volume76
Issue	issue3
Publisher	Okayama University Medical School
Start Page	343
End Page	347
ISSN	0386-300X
NCID	AA00508441
Content Type	Journal Article
language	English
Copyright Holders	Copyright Ⓒ 2022 by Okayama University Medical School
File Version	publisher
Refereed	True
PubMed ID	35790367
Web of Science KeyUT	000823568300015