result 18807 件
| JaLCDOI | 10.18926/11648 |
|---|---|
| Title Alternative | 種々の長さのスペーサーをもつハプテン化ボスファチジルエタノールアミンの新しい合成法 |
| FullText URL | 062_032_037.pdf |
| Author | Ishimori, Yoshio| Yasuda, Tatuji| |
| Abstract | The antigenicity of liposomes sensitized with haptenated phosphatidylethanolamine (PE) and the reactivity of the liposomes with complement depended on the length of the spacer between hapten and PE. To establish the optimal conditions for the assay, haptenated PE's with various length of spacers are required. In the previous method, hapten-spacer molecule was first synthesized to which PE was conjugated. Therefore, even different hapten molecules and different length of spacer molecules were used, every combination of hapten and spacer has to be synthesized. A new procedure for preparing hapten-spacer-PE was described here. We first prepared conjugates between PE and various length of spacer molecule, the terminal of which is an amino residue. These molecules react well with activated hapten molecules, giving a good yield of hapten-spacer-PE. |
| Keywords | Haptenated phosphatidylethanolamine (ハプテン化ホスファチジルエタノールアミン) Spacer (スペーサー) Liposomes (リポソーム) |
| Publication Title | 環境病態研報告 |
| Published Date | 1991-08 |
| Volume | volume62 |
| Start Page | 32 |
| End Page | 37 |
| ISSN | 0913-3771 |
| language | English |
| File Version | publisher |
| NAID | 120002313629 |
| Author | Tomiyama, Koji| |
|---|---|
| Published Date | 2007-03-23 |
| Publication Title | |
| Content Type | Thesis or Dissertation |
| JaLCDOI | 10.18926/11643 |
|---|---|
| Title Alternative | Prevalence of urinary stress incontinence in women |
| FullText URL | 062_023_026.pdf |
| Author | Okuda, Hiroshi| Takatori, Akimasa| Izushi, Michihiro| Yoshida, Junko| Yamagami, Keiko| Sakata, Junko| Tanizaki, Yoshiro| |
| Abstract | 三朝分院外来を訪れた女性患者を対象に尿失禁に関する18項目のアンケート調査を行った。その結果，全体の過半数が尿失禁の経験者であった。腹圧性尿失禁が大部分を占め，高齢になるほど 経産回数が多いほど頻度が高くなる傾向がみられた。そのうちの約1割に尿漏れの頻度と程度が重かった。以上より，尿失禁について積極的な啓蒙，診断，治療の必要性が認められた。 |
| Keywords | 腹圧性尿失禁 (Urinary stress incontinence) |
| Publication Title | 環境病態研報告 |
| Published Date | 1991-08 |
| Volume | volume62 |
| Start Page | 23 |
| End Page | 26 |
| ISSN | 0913-3771 |
| language | Japanese |
| File Version | publisher |
| NAID | 120002313351 |
| Author | Hirano, Atsushi| |
|---|---|
| Published Date | 2007-03-23 |
| Publication Title | |
| Content Type | Thesis or Dissertation |
| Author | Tabayashi, Takayuki| |
|---|---|
| Published Date | 2007-03-23 |
| Publication Title | |
| Content Type | Thesis or Dissertation |
| Author | Muroyama, Ryosuke| |
|---|---|
| Published Date | 2007-03-23 |
| Publication Title | |
| Content Type | Thesis or Dissertation |
| Author | Okazaki, Mikio| |
|---|---|
| Published Date | 2007-03-23 |
| Publication Title | |
| Content Type | Thesis or Dissertation |
| JaLCDOI | 10.18926/11625 |
|---|---|
| Title Alternative | Spa therapy for chronic respiratory diseases - in subjects admitted in 1989. - |
| FullText URL | 061_007_015.pdf |
| Author | Tanizaki, Yoshiro| Sudo, Michiyasu| Kitani, Hikaru| Kawauchi, Kazuhisa| Mifune, Takashi| Tada, Shinya| Takahashi, Kiyoshi| Kimura, Ikuro| |
| Abstract | 1989年1月より12月までの1年間に当院へ入院した慢性呼吸器疾患患者85例（延べ90例）を対象に，その背景因子，臨床的特徴，および温泉療法の臨床効果について検討を加えた。(1)対象85例のうちわけは，気管支喘息65例，肺気腫4例，肺結核症4例，アレルギー性肉芽腫性血管炎3例，閉塞性細気管支炎3例，気管支拡張症2例，慢性気管支炎2例，過敏性肺臓炎2例であり，昨年度と異なり肺結核がやや多かったことが特徴的であった。(2)これら85症例のうち，温泉療法を受けた症例は63例(74.1％)であった。(3)温泉療 法を受けた症例の地域分布では，鳥取県からの入院症例51例では32例(62.7％)であり，同様に岡山県からの入院症例20例では19例(95.0％)，その他の県からの入院症例14例で12例(85.7％)であった。4．温泉療法の臨床効果は，気管支喘息では51例中著効14例，有効27例，やや有効8例，無効2例であり，明らかな有効例は41例（80.3％)であった。 |
| Keywords | 気管支喘息 (Bronchial asthma) 閉塞性細気管支炎 (Obstructive bronchiolitis) 慢性気管支炎 (Chronic bronchitis) 血清コーチゾール値 (Serum cortisol level) 温泉療法 (Spa therapy) |
| Publication Title | 環境病態研報告 |
| Published Date | 1990-09 |
| Volume | volume61 |
| Start Page | 7 |
| End Page | 15 |
| ISSN | 0913-3771 |
| language | Japanese |
| File Version | publisher |
| NAID | 120002313875 |
| JaLCDOI | 10.18926/11579 |
|---|---|
| Title Alternative | 気管支喘息患者末梢血好塩基球の抗ヒトIgEおよびカルシウムイオノフォァA23187に対する反応性について |
| FullText URL | 061_016_022.pdf |
| Author | Tanizaki, Yoshiro| Sudo, Michiyasu| Kitani, Hikaru| Kawauchi, Kazuhisa| Mifune, Takashi| Okuda, Hiroyuki| Komagoe, Haruki| Tada, Shinya| Takahashi, Kiyoshi| Kimura, Ikuro| |
| Abstract | The release of histamine from basophils induced by anti-lgE and calcium ionophore A 23187 ( Cal) was examined in 27 patients with bronchial asthma and 7 healthy subjects, using a whole blood method. (1)The release of histamine induced by anti-IgE and CaI was significantly higher in atopic asthmatics than in non-atopic cases. (2) The histamine release with anti-lgE and CaI was significantly lower in cases with long-term steroid therapy compared to the release in cases without steroid therapy. (3) The release with anti-lgE and CaI was increased in cases with age of 0-39 years and in cases wpth age at onset of 0-39 years. (4) Anti-IgE induced release correlated to a certain extent with the release induced by CaI. These results show that basophil reactivity as expressed by histamine release changes under different conditions. |
| Keywords | Histamine release (ヒスタミン遊離) Basophils (好塩基球) Anti-lgE (抗ヒトIgE) Calcium ionophore A 23187 (カルシウムイオノフォァA23187) Bronchial asthma (気管支喘息) |
| Publication Title | 環境病態研報告 |
| Published Date | 1990-09 |
| Volume | volume61 |
| Start Page | 16 |
| End Page | 22 |
| ISSN | 0913-3771 |
| language | English |
| File Version | publisher |
| NAID | 120002313673 |
| JaLCDOI | 10.18926/fest/11542 |
|---|---|
| Title Alternative | Preparation and In Vitro Release Property of PLA Microspheres Enclosing Antitumor Agent |
| FullText URL | 006_103_106.pdf |
| Author | Nishino, Satoru| Yoshizawa, Hidekazu| Natsugoe, Shoji| Aiko, Takashi| Hatate, Yasuo| Kitamura, Yoshiro| |
| Abstract | Recently, many antitumor agents developed. Irinotecan hycrochloride (CPT) has a great side effect even though it is well effective against the cancer. Drug delivery system (DDS) medicine indicates that the release rate of medicine is constant for a long time. Therefore, in order to materialize the general idea of DDS, we applied microencapsulation technique to prepare biodegradable polymer microspheres (MS) enclosing antitumor drug having no side effect. Polylactide microparticles enclosing antitumor agent were prepared by solvent evaporation method under various operation conditions. The effects of operation parameter on release rate of drug and morphology of microparticles were studied. |
| Keywords | DDS microparticle polylactide antitumor agent solvent evaporation DSC |
| Publication Title | 岡山大学環境理工学部研究報告 |
| Published Date | 2001-02-28 |
| Volume | volume6 |
| Issue | issue1 |
| Start Page | 103 |
| End Page | 106 |
| ISSN | 1341-9099 |
| language | Japanese |
| File Version | publisher |
| NAID | 120002314051 |
| Author | Chikamori, Ken-ichi| |
|---|---|
| Published Date | 2007-03-23 |
| Publication Title | |
| Content Type | Thesis or Dissertation |
| Author | Uehara, Shinya| |
|---|---|
| Published Date | 2007-03-23 |
| Publication Title | |
| Content Type | Thesis or Dissertation |
| Author | So, Jun-ichi| |
|---|---|
| Published Date | 2007-03-23 |
| Publication Title | |
| Content Type | Thesis or Dissertation |
| Author | Ohtani, Yu| |
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| Published Date | 2007-03-23 |
| Publication Title | |
| Content Type | Thesis or Dissertation |
| Author | Fujimoto, Tsuyoshi| |
|---|---|
| Published Date | 2007-03-23 |
| Publication Title | |
| Content Type | Thesis or Dissertation |
| Author | Suemaru, Shunji| |
|---|---|
| Published Date | 2007-03-23 |
| Publication Title | |
| Content Type | Thesis or Dissertation |
| Author | Koyama, Fumihiko| |
|---|---|
| Published Date | 2007-03-23 |
| Publication Title | |
| Content Type | Thesis or Dissertation |
| JaLCDOI | 10.18926/11019 |
|---|---|
| FullText URL | 23_0063_0074.pdf |
| Author | 山本 浩史| |
| Abstract | 石井十次は、明治時代に岡山孤児院を設立し、孤児救済を実践したプロテスタントであり篤志家である。社会保障も確立していない明治時代の下層社会は、これらの民間人の事前事業により支えられていたといっても過言ではない。石井は慶應元年、宮崎に生まれる。その後明治15年、岡山縣甲種医学校で医学を、そして、岡山教会でキリスト教を学ぶために岡山へ遊学する。石井は医学を学び、信仰によりプロテスタンティズムを深めていくなかで、偶然に貧児と出会い、医師を目指す傍らで孤児救済に関わり始める。このような経過のなかで、石井は孤児救済へとまい進していくのだが、この背景には天職観があり、これが大きな原動力となっていた。そこで本論文の目的は、石井を孤児救済にまい進させた天職観に注目し、この思想の成立について考察することにある。天職観が形成される過程を考察することは、石井における孤児救済の原点を知ることであり、石井が孤児救済にまい進したのか、その答えを探す一つの手がかりになると考える |
| Keywords | 石井十次 天職観 孤児救済 |
| Publication Title | 岡山大学大学院社会文化科学研究科紀要 |
| Published Date | 2007-03 |
| Volume | volume23 |
| Issue | issue1 |
| Start Page | 63 |
| End Page | 74 |
| language | Japanese |
| File Version | publisher |
| NAID | 120002313334 |
| Author | Morizane, Shin| |
|---|---|
| Published Date | 2006-12-31 |
| Publication Title | |
| Content Type | Thesis or Dissertation |
| Author | Morita, Yukitaka| |
|---|---|
| Published Date | 2006-12-31 |
| Publication Title | |
| Content Type | Thesis or Dissertation |
