result 3070 件
| Author | Ueda, Youki| Takeda, Midori| Mori, Kyoko| Dansako, Hiromichi| Wakita, Takaji| Kim, Hye-Sook| Sato, Akira| Wataya, Yusuke| Ikeda, Masanori| Kato, Nobuyuki| |
|---|---|
| Published Date | 2013-08-30 |
| Publication Title | PLOS ONE |
| Volume | volume8 |
| Issue | issue8 |
| Content Type | Journal Article |
| Author | Ishikawa, Atsushi| Tanaka, Takuo| |
|---|---|
| Published Date | 2015 |
| Publication Title | Scientific reports |
| Volume | volume5 |
| Content Type | Journal Article |
| Author | Michiue, Hiroyuki| |
|---|---|
| Published Date | 2015-09 |
| Publication Title | Okayama University Medical Research Updates |
| Volume | volume14 |
| Content Type | Others |
| Author | Matsumoto, Masakazu| Yagasaki, Takuma| Tanaka, Hideki| |
|---|---|
| Published Date | 2015-11-06 |
| Publication Title | Physical Review Letters |
| Volume | volume115 |
| Issue | issue19 |
| Content Type | Journal Article |
| JaLCDOI | 10.18926/AMO/53908 |
|---|---|
| FullText URL | 69_6_339.pdf |
| Author | Senoo, Miki| Nakatsuka, Mikiya| |
| Abstract | Pregnant women with uterine leiomyomas may experience anxiety toward their pregnancies and unfavorable feelings toward their infants. From March to July 2010, we distributed anonymous self-recorded questionnaires to 200 pregnant women who visited Okayama Central Hospital for an antenatal check-up after informed consent was provided, and 132 women (23 pregnant women with uterine leiomyomas) were included in our study. Among the multiparous women in their first trimester, the women with uterine leiomyomas had a higher rate of anxiety than those without uterine leiomyomas. ʻAvoidanceʼ scores on the Feeling Toward the Baby Scale were significantly higher in the leiomyoma group. The conflict index scores tended to be higher in the leiomyoma group. A multivariate analysis revealed no factors associated with trait-anxiety scores, whereas high state-anxiety scores were correlated with low age;however, there was no correlation between these scores and uterine leiomyomas. Although no factors were associated with State-Trait Anxiety Inventory (STAI) and approach scores toward the baby, avoidance and conflict index scores were associated with the existence of uterine leiomyomas. In pregnant women with uterine leiomyomas, efforts should be made to reduce anxiety in the first trimester, and support should be provided to help these women develop positive feelings toward their babies. |
| Keywords | pregnancy uterine leiomyomas anxiety feelings toward the baby pregnancy loss |
| Amo Type | Original Article |
| Publication Title | Acta Medica Okayama |
| Published Date | 2015-12 |
| Volume | volume69 |
| Issue | issue6 |
| Publisher | Okayama University Medical School |
| Start Page | 339 |
| End Page | 348 |
| ISSN | 0386-300X |
| NCID | AA00508441 |
| Content Type | Journal Article |
| language | English |
| Copyright Holders | CopyrightⒸ 2015 by Okayama University Medical School |
| File Version | publisher |
| Refereed | True |
| PubMed ID | 26690244 |
| Web of Science KeyUT | 000368434500003 |
| Related Url | http://doi.org/10.18926/AMO/54008 |
| Author | Kitamura, Shinji| Sakurai, Hiroyuki| Makino, Hirofumi| |
|---|---|
| Published Date | 2015-03 |
| Publication Title | Stem cells |
| Volume | volume33 |
| Issue | issue3 |
| Content Type | Journal Article |
| FullText URL | K0005220_abstract_review .pdf K0005220_fulltext.pdf |
|---|---|
| Author | Yano, Jitsuro| |
| Published Date | 2015-09-30 |
| Content Type | Thesis or Dissertation |
| Grant Number | 甲第5220号 |
| Granted Date | 2015-09-30 |
| Thesis Type | Doctor of Philosophy in Dental Science |
| Grantor | 岡山大学 |
| language | English |
| Title Alternative | A case report of giant ectopic pheochromocytoma conversion therapy with radioisotope therapy and chemotherapy followed by curative resection |
|---|---|
| FullText URL | 127_213.pdf |
| Author | Yasui, Kazuya| Umeda, Yuzo| Kumano, Kenjiro| Tabata, Masahiro| Otsuka, Fumio| Yagi, Takahito| Fujiwara, Toshiyoshi| |
| Abstract | A 46-year-old man was found to be positive for occult blood at a medical checkup and was revealed to have a 14-cm tumor on the right side of abdominal aorta by a subsequent abdominal CT scan. The endocrinology laboratory data showed elevations in the levels of serum noradrenaline, and ectopic pheochromocytoma was suspected. The tumor was compressing the inferior vena cava and portal vein, the superior mesenteric artery and the pancreas. Since it would be difficult to cure by operation, neoadjuvant therapy was started using radioisotope therapy by I-131 metaiodobenzylguanidine (131I-MIBG) and chemotherapy (CVD therapy ; cyclophosphamide, vincristine, dacarbazine). He was treated with three courses of radioisotope therapy and 16 courses of chemotherapy, which significantly reduced the tumor size. This made radical resection possible ; we were able to avoid the merger excision of great vessels and other organs. On pathological and immunopathological findings, the tumor was diagnosed as ectopic pheochromocytoma. Regarding the safety and curability of the treatment, neoadjuvant therapy may be useful in treating very large tumors that show invasion of other organs. |
| Keywords | 異所性褐色細胞腫（ectopic pheochromocytoma） 化学療法（chemo therapy） 131I-MIBG |
| Publication Title | 岡山医学会雑誌 |
| Published Date | 2015-12-01 |
| Volume | volume127 |
| Issue | issue3 |
| Start Page | 213 |
| End Page | 218 |
| ISSN | 0030-1558 |
| Related Url | isVersionOf https://doi.org/10.4044/joma.127.213 |
| language | Japanese |
| Copyright Holders | Copyright (c) 2015 岡山医学会 |
| File Version | publisher |
| DOI | 10.4044/joma.127.213 |
| NAID | 130005116814 |
| Title Alternative | Non-high-output cardiac failure in patients undergoing hemodialysis through an arteriovenous shunt |
|---|---|
| FullText URL | 127_203.pdf |
| Author | Ugawa, Toyomu| |
| Abstract | Background: Hemodialysis-related heart failure has been considered to be associated with excessive blood flow through the arteriovenous (AV) shunt used for vascular access. However, some patients undergoing dialysis have heart failure in the absence of an increase in cardiac output (CO) related to shunt blood-flow loading because the loading cannot be compensated for by increasing CO. This condition may be challenging to manage ; thus, early diagnosis is important. Methods and Results: Twelve patients (mean age, 71 years ; 9 men) with end-stage renal disease, dialysis-related heart failure, a high brain natriuretic peptide (BNP) level, and a mean New York Heart Association (NYHA) class of II underwent AV shunt closure. Their cardiac index (CI), pre- and post-dialysis BNP levels, and several cardiac variables were assessed pre- and postoperatively. All patients achieved relief of heart failure symptoms and a reduction in NYHA class after AV closure, but six patients had a postoperative increase in CI (the "non-high-output" cardiac failure group), whereas the other six had a decrease in CI (the "high-output" cardiac failure group). The high-output patients had greater improvements in BNP levels and most cardiac variables compared to the non-high-output group ; therefore, the heart failure in the non-high-output patients was considered more serious than that in the high-output group. Conclusions: The selection of effective strategies for treating dialysis-related heart failure may depend partly on identifying which patients have non-high-output failure. Such identification requires serial measurements of BNP levels and evaluations of cardiac variables other than the ejection fraction. |
| Keywords | 心拍出量（cardiac output） 心不全（heart failure） 脳性ナトリウム利尿ペプチド（brain natriuretic peptide） 非過大シャント心不全（non-high-output cardiac failure） 腎臓（kidney） |
| Publication Title | 岡山医学会雑誌 |
| Published Date | 2015-12-01 |
| Volume | volume127 |
| Issue | issue3 |
| Start Page | 203 |
| End Page | 207 |
| ISSN | 0030-1558 |
| Related Url | isVersionOf https://doi.org/10.4044/joma.127.203 |
| language | Japanese |
| Copyright Holders | Copyright (c) 2015 岡山医学会 |
| File Version | publisher |
| DOI | 10.4044/joma.127.203 |
| NAID | 130005116810 |
| Title Alternative | Basic and clinical research regarding vascular endothelial function |
|---|---|
| FullText URL | 127_187.pdf |
| Author | Tsukahara, Hirokazu| |
| Keywords | アルギニン代謝 一酸化窒素 ガス生物学 血管内皮学 酸化ストレス |
| Publication Title | 岡山医学会雑誌 |
| Published Date | 2015-12-01 |
| Volume | volume127 |
| Issue | issue3 |
| Start Page | 187 |
| End Page | 195 |
| ISSN | 0030-1558 |
| language | Japanese |
| Copyright Holders | Copyright (c) 2015 岡山医学会 |
| File Version | publisher |
| DOI | 10.4044/joma.127.187 |
| NAID | 130005116819 |
| JaLCDOI | 10.18926/AMO/53678 |
|---|---|
| FullText URL | 69_5_313.pdf |
| Author | Narita, Akiko| Seguchi, Jiro| Shiraga, Fumio| |
| Abstract | Paecilomyces lilacinus (P. lilacinus) is a rare cause of fungal scleritis. We herein report a case of P. lilacinus-induced scleritis following bleb-associated endophthalmitis after trabeculectomy that was successfully treated with surgical excision of the affected sclera in combination with antifungal medication. An 85-year-old female underwent trabeculectomy of the left eye. A dellen formed in the corneal periphery due to limbal elevation of the filtering bleb and progressed to an infectious corneal ulcer, leading to blebitis. Eight days after the onset of blebitis, the patient was diagnosed with endophthalmitis, which resolved after vitrectomy. The growth of P. lilacinus was identified on swabs of the conjunctiva and the corneal specimen. Scleritis developed after the resolution of the endophthalmitis, and an early excision of the affected sclera, in addition to antifungal medication, resolved it completely. However, the scleritis recurred in a different region of the left eye. After 7 months of antifungal medication, the left eye showed no residual infection. When treating P. lilacinus-induced scleritis, surgical excision of the affected sclera has been shown to be an effective treatment strategy. Nevertheless, it is possible that the infection may recur in another part of the eyeball after the complete resolution of the primary lesion. |
| Keywords | Paecilomyces lilacinus scleritis trabeculectomy |
| Amo Type | Case Report |
| Publication Title | Acta Medica Okayama |
| Published Date | 2015-10 |
| Volume | volume69 |
| Issue | issue5 |
| Publisher | Okayama University Medical School |
| Start Page | 313 |
| End Page | 318 |
| ISSN | 0386-300X |
| NCID | AA00508441 |
| Content Type | Journal Article |
| language | English |
| Copyright Holders | CopyrightⒸ 2015 by Okayama University Medical School |
| File Version | publisher |
| Refereed | True |
| PubMed ID | 26490029 |
| Web of Science KeyUT | 000365519600008 |
| JaLCDOI | 10.18926/AMO/53673 |
|---|---|
| FullText URL | 69_5_275.pdf |
| Author | Nosaka, Nobuyuki| Goda, Yu| Knaup, Emily| Tsukahara, Kohei| Yumoto, Tetsuya| Ugawa, Toyomu| Ujike, Yoshihito| |
| Abstract | We sought to identify the incidence, injury patterns, and financial burden of ladder fall injuries to provide a reference for reinforcing guidelines on the prevention of such injuries. We enrolled the patients who were injured in a ladder-related fall and required intensive care between April 2012 and March 2014 at Okayama University Hospital, a tertiary care hospital in Okayama City:9 patients injured in 7 stepladder falls and 2 straight ladder falls. The median patient age was 69 years, and 8 were males. Six falls occurred in non-occupational settings. Head injuries predominated, and the injury severity score ranged from 2 to 35 (mean＝21±12). At the time of discharge from the intensive care unit, one patient had died and 5 patients had some neurological disabilities. The case fatality rate was 11%. The total cost of care during the review period was ￥16,705,794, with a mean cost of ￥1,856,199 per patient. Ladder fall injuries are associated with a high rate of neurological sequelae and pose a financial burden on the health insurance system. A prevention education campaign targeting at older-aged males in non-occupational settings may be a worthwhile health service investment in this community. |
| Keywords | accidental falls accident prevention hospital costs injuries ladder |
| Amo Type | Original Article |
| Publication Title | Acta Medica Okayama |
| Published Date | 2015-10 |
| Volume | volume69 |
| Issue | issue5 |
| Publisher | Okayama University Medical School |
| Start Page | 275 |
| End Page | 278 |
| ISSN | 0386-300X |
| NCID | AA00508441 |
| Content Type | Journal Article |
| language | English |
| Copyright Holders | CopyrightⒸ 2015 by Okayama University Medical School |
| File Version | publisher |
| Refereed | True |
| PubMed ID | 26490024 |
| Web of Science KeyUT | 000365519600003 |
| Author | Dansako, Hiromichi| Ueda, Youki| Okumura, Nobuaki| Satoh, Shinya| Sugiyama, Masaya| Mizokami, Masashi| Ikeda, Masanori| Kato, Nobuyuki| |
|---|---|
| Published Date | 2015 |
| Publication Title | The FEBS journal |
| Content Type | Journal Article |
| Author | Matsuo, Toshihiko| |
|---|---|
| Published Date | 2015-09-21 |
| Publication Title | SpringerPlus |
| Volume | volume4 |
| Content Type | Journal Article |
| Author | Kyotaro, Ohno| Yasuharu, Sato| Koh-ichi, Ohshima| Katsuyoshi, Takata| Tomoko, Miyata-Takata| Mai, Takeuchi| Yuka, Gion| Tomoyasu, Tachibana| Yorihisa, Orita| Toshihiro, Ito| Steven, H. Swerdlow| Tadashi, Yoshino| |
|---|---|
| Published Date | 2015 |
| Publication Title | Scientific Reports |
| Volume | volume5 |
| Content Type | Journal Article |
| FullText URL | Nature-Shen manuscript for deposit(151002).pdf |
|---|---|
| Author | Suga, Michihiro| Akita, Fusamichi| Hirata, Kunio| Ueno, Go| Murakami, Hironori| Nakajima, Yoshiki| Shimizu, Tetsuya| Yamashita, Keitaro| Yamamoto, Masaki| Ago, Hideo| Shen, Jian-Ren| |
| Note | The final publication is available at Nature via http://dx.doi.org/10.1038/nature13991| |
| Published Date | 2015-01-01 |
| Publication Title | Nature |
| Volume | volume517 |
| Publisher | Nature Publishing Group |
| Start Page | 99 |
| End Page | 103 |
| ISSN | 0028-0836 |
| NCID | AA00752384 |
| Content Type | Journal Article |
| language | English |
| OAI-PMH Set | 岡山大学 |
| Copyright Holders | © 2015 Michihiro Suga et al.; licensee Macmillan Publishers Limited. |
| File Version | author |
| PubMed ID | 25470056 |
| DOI | 10.1038/nature13991 |
| Web of Science KeyUT | 000347178400043 |
| Author | Ebinuma, Takayuki| Soga, Yoshihiko| Sato, Takamaro| Matsunaga, Kazuyuki| Kudo, Chieko| Maeda, Hiroshi| Maeda, Yoshinobu| Tanimoto, Mitsune| Takashiba, Shogo| |
|---|---|
| Published Date | 2014-06 |
| Publication Title | Supportive Care in Cancer |
| Volume | volume22 |
| Issue | issue6 |
| Content Type | Journal Article |
| Author | Mochizuki, Kenji| Koga, Kenichiro| |
|---|---|
| Published Date | 2015-07-07 |
| Publication Title | Proceedings of the National Academy of Sciences of the United States of America |
| Volume | volume112 |
| Issue | issue27 |
| Content Type | Journal Article |
| FullText URL | JofPlantResearch_128(6)875.pdf |
|---|---|
| Author | Takatani, Shogo| Otani, Kento| Kanazawa, Mai| Takahashi, Taku| Motose, Hiroyasu| |
| Keywords | NIMA-related kinase Phosphorylation Tubulin Microtubule Cell expansion Cell division |
| Note | The final publication is available at Springer via http://dx.doi.org/10.1007/s10265-015-0751-6 ,| |
| Published Date | 2015-11 |
| Publication Title | Journal of Plant Research |
| Volume | volume128 |
| Issue | issue6 |
| Publisher | Springer Japan |
| Start Page | 875 |
| End Page | 891 |
| ISSN | 0918-9440 |
| NCID | AA10900218 |
| Content Type | Journal Article |
| language | English |
| OAI-PMH Set | 岡山大学 |
| Copyright Holders | The Botanical Society of Japan and Springer Japan |
| File Version | author |
| PubMed ID | 26354760 |
| DOI | 10.1007/s10265-015-0751-6 |
| Web of Science KeyUT | 000364511100001 |
| JaLCDOI | 10.18926/AMO/53559 |
|---|---|
| FullText URL | 69_4_227.pdf |
| Author | Nakagawa, Naohisa| Koda, Hiromi| Nitta, Noriko| Nakahara, Yukie| Uno, Jiro| Hashimoto, Toru| Nakahori, Takashi| Hasegawa, Masaaki| Kataoka, Mikio| |
| Abstract | Previous reports have shown that some ovarian endometrioid adenocarcinomas and ovarian clear cell adenocarcinomas derive from ovarian endometriosis (OE), and that endocervical-like mucinous borderline ovarian tumors are associated with OE. We examined the relationship between the staging and histological subtypes of OE or epithelial ovarian tumors (EOT) and the serum levels of carbohydrate antigen 19-9 (CA19-9) and carbohydrate antigen 125 (CA125) to evaluate the potential of these markers for preoperative diagnosis. First, we analyzed the preoperative serum levels of CA19-9 and CA125 in 195 patients who were histopathologically diagnosed with OE or EOT. We then performed a case-control study in which 308 women were enrolled, the 195 women described above and 113 healthy women as control subjects. Serum CA19-9 and CA125 levels were found to be useful in differentiating between OE and serous adenocarcinoma, but not between OE and other EOT. Moreover, serum CA19-9 levels were useful for preoperative assessment between OE and stage I mucinous borderline ovarian tumors, with or without the interstitial infiltration. In addition, considering that the serum CA19-9 levels in stage I mucinous borderline ovarian tumors were elevated via the interstitial infiltration of leukocytes and that precancerous lesions are associated with a cancerous glycosylation disorder in the process of inflammatory carcinogenesis, the CA19-9 level may be considered a suitable biomarker for estimating drug susceptibility. |
| Keywords | ovarian endometriosis epithelial ovarian tumors histological subtype carbohydrate antigen 19-9 carbohydrate antigen 125 |
| Amo Type | Original Article |
| Publication Title | Acta Medica Okayama |
| Published Date | 2015-08 |
| Volume | volume69 |
| Issue | issue4 |
| Publisher | Okayama University Medical School |
| Start Page | 227 |
| End Page | 235 |
| ISSN | 0386-300X |
| NCID | AA00508441 |
| Content Type | Journal Article |
| language | English |
| Copyright Holders | CopyrightⒸ 2015 by Okayama University Medical School |
| File Version | publisher |
| Refereed | True |
| PubMed ID | 26289914 |
| Web of Science KeyUT | 000365519100006 |
