検索結果 - OKAYAMA UNIVERSITY SCIENTIFIC ACHIEVEMENT REPOSITORY

Anaplastic Lymphoma Kinase Fusion: A Review of Therapeutic Drugs and Treatment Strategies

JaLCDOI	10.18926/AMO/60796
FullText URL	74_5_371.pdf
Author	Makimoto, Go\| Ohashi, Kadoaki\| Maeda, Yoshinobu\| Kiura, Katsuyuki\|
Abstract	The prognosis of advanced non-small cell lung cancer (NSCLC) patients has improved in recent decades, especially for patients with an oncogenic driver mutation. Anaplastic lymphoma kinase (ALK) tyrosine kinase inhibitors (TKIs) are effective for patients with the echinoderm microtubule-associated protein-like 4-ALK fusion gene. Several ALK-TKIs have been established: the first-generation ALK-TKI, crizotinib; second-generation ALK-TKIs, alectinib and ceritinib; and third-generation ALK-TKI, lorlatinib. Some ALK-TKIs are effective for tumors that are resistant to other ALK-TKIs; however, as is known in epidermal growth factor receptormutant lung cancer, tumor resistance is inevitable. ALK-positive NSCLCs acquire resistance via various mechanisms, making it a heterogeneous disease. Therefore, it is necessary to develop next-generation treatment strategies, such as the use of next-generation ALK-TKIs for secondary mutations, or combination therapies with ALK-TKIs and other TKIs. In this review, we summarize the development and use of ALK-TKIs, prior pivotal clinical trials, and resistance mechanisms.
Keywords	lung cancer anaplastic lymphoma kinase tyrosine kinase inhibitors resistance mechanism
Amo Type	Review
Publication Title	Acta Medica Okayama
Published Date	2020-10
Volume	volume74
Issue	issue5
Publisher	Okayama University Medical School
Start Page	371
End Page	379
ISSN	0386-300X
NCID	AA00508441
Content Type	Journal Article
language	English
Copyright Holders	CopyrightⒸ 2020 by Okayama University Medical School
File Version	publisher
Refereed	True
PubMed ID	33106692
Web of Science KeyUT	000581970100001
NAID	120006892922

Structure and phase behavior of high-density ice from molecular-dynamics simulations with the ReaxFF potential

FullText URL	fulltext.pdf
Author	Adachi, Yuji\| Koga, Kenichiro\|
Note	This article may be downloaded for personal use only. Any other use requires prior permission of the author and AIP Publishing. This article appeared in Yuji Adachi and Kenichiro Koga Structure and phase behavior of highdensity ice from molecular-dynamics simulations with the ReaxFF potential. J. Chem. Phys. 153, 114501 (2020) and may be found at https://doi.org/10.1063/5.0016565.\|
Published Date	2020-09-16
Publication Title	Journal of Chemical Physics
Volume	volume153
Issue	issue11
Publisher	American Institute of Physics
Start Page	114501
ISSN	0021-9606
NCID	AA00694991
Content Type	Journal Article
Copyright Holders	© 2020 Author(s)
File Version	publisher
PubMed ID	32962394
DOI	10.1063/5.0016565
Web of Science KeyUT	000574657400001
Related Url	isVersionOf https://doi.org/10.1063/5.0016565

A nationwide trend analysis in the incidence and mortality of Creutzfeldt-Jakob disease in Japan between 2005 and 2014

FullText URL	fulltext.pdf
Author	Nishimura, Yoshito\| Harada, Ko\| Koyama, Toshihiro\| Hagiya, Hideharu\| Otsuka, Fumio\|
Keywords	Epidemiology Health policy Neurological disorders
Published Date	2020-09-23
Publication Title	Scientific Reports
Volume	volume10
Issue	issue1
Publisher	Nature Research
Start Page	15509
ISSN	2045-2322
Content Type	Journal Article
language	English
OAI-PMH Set	岡山大学
Copyright Holders	© The Author(s) 2020
File Version	publisher
PubMed ID	32968173
DOI	10.1038/s41598-020-72519-0
Web of Science KeyUT	000573849300037
Related Url	isVersionOf https://doi.org/10.1038/s41598-020-72519-0

Super-chiral vibrational spectroscopy with metasurfaces for high-sensitive identification of alanine enantiomers

FullText URL	APL_117_101103.pdf
Author	Iida, Takumi \| Ishikawa, Atsushi\| Tanaka, Takuo\| Muranaka, Atsuya\| Uchiyama, Masanobu\| Hayashi, Yasuhiko\| Tsuruta, Kenji\|
Note	This article may be downloaded for personal use only. Any other use requires prior permission of the author and AIP Publishing. This article appeared in Takumi Iida et. al. Super-chiral vibrational spectroscopy with metasurfaces for high-sensitive identification of alanine enantiomers. Appl. Phys. Lett. 117, 101103 (2020) and may be found at https://doi.org/10.1063/5.0012331.\|
Published Date	2020-09-09
Publication Title	Applied Physics Letters
Volume	volume117
Issue	issue10
Publisher	American Institute of Physics
Start Page	101103
ISSN	0003-6951
NCID	AA00543431
Content Type	Journal Article
language	English
OAI-PMH Set	岡山大学
File Version	publisher
DOI	10.1063/5.0012331
Web of Science KeyUT	000571581400002
Related Url	isVersionOf https://doi.org/10.1063/5.0012331

Facile synthesis of picenes incorporating imide moieties at both edges of the molecule and their application to n-channel field-effect transistors

FullText URL	RSC_Adv_10.pdf
Author	Guo, Yuxin\| Yoshioka, Kaito\| Hamao, Shino\| Kubozono, Yoshihiro\| Tani, Fumito\| Goto, Kenta\| Okamoto, Hideki\|
Published Date	2020-08-26
Publication Title	RSC Advances
Volume	volume10
Issue	issue52
Publisher	Royal Society of Chemistry
Start Page	31547
End Page	31552
ISSN	2046-2069
Content Type	Journal Article
language	English
OAI-PMH Set	岡山大学
Copyright Holders	© The Royal Society of Chemistry
File Version	publisher
DOI	10.1039/D0RA06629J
Web of Science KeyUT	000566579400055
Related Url	isVersionOf https://doi.org/10.1039/D0RA06629J

Integrated Synthesis of Thienyl Thioethers and Thieno[3,2-b]thiophenes via 1-Benzothiophen-3(2H)-ones

FullText URL	Synlett_fulltext.pdf
Author	Mitsudo, Koichi\| Habara, Nanae\| Kobashi, Yoshiak\| Kurimoto, Yuji\| Mandai, Hiroki\| Suga, Seiji\|
Keywords	thienyl thioethers thioetherification one-pot synthesis metal-free halide-free thienoacenes
Note	This is an Accepted Manuscript of an article published by Thieme Gruppe.\|
Published Date	2020-09-21
Publication Title	Synlett: Accounts and Rapid Communications in Synthetic Organic Chemistry
Volume	volume31
Issue	issue19
Publisher	Thieme Gruppe
Start Page	1947
End Page	1952
ISSN	0936-5214
NCID	AA10731110
Content Type	Journal Article
language	English
OAI-PMH Set	岡山大学
File Version	author
DOI	10.1055/s-0040-1707280
Web of Science KeyUT	000571827200001
Related Url	isVersionOf https://www.doi.org/10.1055/s-0040-1707280

Electrochemical Synthesis of Thienoacene Derivatives: Transition‐Metal‐Free Dehydrogenative C−S Coupling Promoted by a Halogen Mediator

FullText URL	AC_Int_ed_59_20.pdf
Author	Mitsudo, Koichi\| Matsuo, Ren\| Yonezawa, Toki\| Inoue, Haruka\| Mandai, Hiroki\| Suga, Seiji\|
Keywords	cross-coupling cyclization electrochemistry heterocycles synthetic methods
Note	This is the peer reviewed version of the following article: Mitsudo Koichi et. al. Electrochemical Synthesis of Thienoacene Derivatives: Transition‐Metal‐Free Dehydrogenative C−S Coupling Promoted by a Halogen Mediator. Angewandte Chemie International Edition 59(20) 7803-7807(2020), which has been published in final form at https://doi.org/10.1002/anie.202001149. This article may be used for non-commercial purposes in accordance with Wiley Terms and Conditions for Use of Self-Archived Versions This fulltext is available in Feb. 2021.\|
Published Date	2020-02-20
Publication Title	Angewandte Chemie International Edition
Volume	volume59
Issue	issue20
Publisher	Wiley
Start Page	7803
End Page	7807
ISSN	1433-7851
NCID	AA11614189
Content Type	Journal Article
language	English
OAI-PMH Set	岡山大学
File Version	author
PubMed ID	32077555
DOI	10.1002/anie.202001149
Web of Science KeyUT	000520531700001
Related Url	isVersionOf https://doi.org/10.1002/anie.202001149

Dysfunction of CD8+PD-1+T cells in type 2 diabetes caused by the impairment of metabolism-immune axis

FullText URL	fulltext.pdf
Author	Nojima, Ichiro\| Eikawa, Shingo\| Tomonobu, Nahoko\| Hada, Yoshiko\| Kajitani, Nobuo\| Teshigawara, Sanae\| Miyamoto, Satoshi\| Tone, Atsuhito\| Uchida, Haruhito A.\| Nakatsuka, Atsuko\| Eguchi, Jun\| Shikata, Kenichi\| Udono, Heiichiro\| Wada, Jun\|
Keywords	Cytokines Diabetes Endocrine system and metabolic diseases Immunology Tumour immunology
Published Date	2020-09-10
Publication Title	Scientific Reports
Volume	volume10
Issue	issue1
Publisher	Nature Research
Start Page	14928
ISSN	2045-2322
Content Type	Journal Article
language	English
OAI-PMH Set	岡山大学
Copyright Holders	© The Author(s) 2020
File Version	publisher
PubMed ID	32913271
DOI	10.1038/s41598-020-71946-3
Web of Science KeyUT	000571915100049
Related Url	isVersionOf https://doi.org/10.1038/s41598-020-71946-3

Hadaka Virus 1: a Capsidless Eleven-Segmented Positive-Sense Single-Stranded RNA Virus from a Phytopathogenic Fungus, Fusarium oxysporum

FullText URL	fulltext.pdf
Author	Sato, Yukiyo\| Shamsi, Wajeeha\| Jamal, Atif\| Bhatti, Muhammad Faraz\| Kondo, Hideki\| Suzuki, Nobuhiro\|
Keywords	fungal virus polymycovirus Fusarium oxysporum multisegmented RNA virus capsidless neo-virus lifestyle
Published Date	2020-05-26
Publication Title	mBio
Volume	volume11
Issue	issue3
Publisher	American Society for Microbiology
Start Page	e00450-20
ISSN	2150-7511
Content Type	Journal Article
language	English
OAI-PMH Set	岡山大学
Copyright Holders	© 2020 Sato et al.
File Version	publisher
PubMed ID	32457242
DOI	10.1128/mBio.00450-20
Web of Science KeyUT	000572051800015
Related Url	isVersionOf https://doi.org/10.1128/mBio.00450-20

Identification of effector candidate genes of Rhizoctonia solani AG-1 IA expressed during infection in Brachypodium distachyon

FullText URL	fulltext.pdf
Author	Abdelsalam, Sobhy S. H.\| Kouzai, Yusuke\| Watanabe, Megumi\| Inoue, Komaki\| Matsui, Hidenori\| Yamamoto, Mikihiro\| Ichinose, Yuki\| Toyoda, Kazuhiro\| Tsuge, Seiji\| Mochida, Keiichi\| Noutoshi, Yoshiteru\|
Keywords	Fungi Microbiology Pathogens Plant immunity Plant sciences Transcription
Published Date	2020-09-10
Publication Title	Scientific Reports
Volume	volume10
Issue	issue1
Publisher	Nature Research
Start Page	14889
ISSN	2045-2322
Content Type	Journal Article
language	English
OAI-PMH Set	岡山大学
Copyright Holders	© The Author(s) 2020
File Version	publisher
PubMed ID	32913311
DOI	10.1038/s41598-020-71968-x
Web of Science KeyUT	000571915100010
Related Url	isVersionOf https://doi.org/10.1038/s41598-020-71968-x

Low temperature modulates natural peel degreening in lemon fruit independently of endogenous ethylene

FullText URL	fulltext.pdf
Author	Mitalo, Oscar W.\| Otsuki, Takumi\| Okada, Rui\| Obitsu, Saeka\| Masuda, Kanae\| Hojo, Yuko\| Matsuura, Takakazu\| Mori, Izumi C.\| Abe, Daigo\| Asiche, William O.\| Akagi, Takashi\| Kubo, Yasutaka\| Ushijima, Koichiro\|
Keywords	1-methylcyclopropene carotenoids chlorophyll Citrus limon ethylene low temperature peel degreening phytohormones transcriptome
Published Date	2020-05-06
Publication Title	Journal of Experimental Botany
Volume	volume71
Issue	issue16
Publisher	Oxford University Press
Start Page	4778
End Page	4796
ISSN	0022-0957
NCID	AA00697526
Content Type	Journal Article
language	English
OAI-PMH Set	岡山大学
Copyright Holders	© The Author(s) 2020.
File Version	publisher
PubMed ID	32374848
DOI	10.1093/jxb/eraa206
Web of Science KeyUT	000573250000015
Related Url	isVersionOf https://doi.org/10.1093/jxb/eraa206

A study for 2-D indoor localization using multiple leaky coaxial cables

FullText URL	fulltext.pdf
Author	Zhu, Junjie\| Hou, Pengcheng\| Hou, Yafei\| Denno, Satoshi\| Okada, Minoru\|
Keywords	Leaky coaxial cable Capacity MIMO
Published Date	2020-09-25
Publication Title	APSIPA Transactions on Signal and Information Processing
Volume	volume9
Publisher	Cambridge University Press
Start Page	e20
ISSN	2048-7703
Content Type	Journal Article
language	English
OAI-PMH Set	岡山大学
Copyright Holders	© The Author(s)
File Version	publisher
DOI	10.1017/ATSIP.2020.18
Web of Science KeyUT	000572654600001
Related Url	isVersionOf https://doi.org/10.1017/ATSIP.2020.18

Long-term exposure to nitrogen dioxide and natural-cause and cause-specific mortality in Japan

FullText URL	fulltext.pdf Tables.pdf Figure1.tif
Author	Yorifuji, Takashi\| Kashima, Saori\|
Keywords	Air pollution Epidemiology Nitrogen dioxide Lung cancer Mortality
Note	© 2020 Elsevier B.V. This manuscript version is made available under the CC-BY-NC-ND 4.0 License. http://creativecommons.org/licenses/by-nc-nd/4.0/. This is the accepted manuscript version. The formal published version is available at 10.1016/j.scitotenv.2020.140465\|
Published Date	2020-06-25
Publication Title	Science of The Total Environment
Volume	volume741
Issue	issue1
Publisher	Elsevier
Start Page	140465
ISSN	0048-9697
NCID	AA00836666
Content Type	Journal Article
language	English
OAI-PMH Set	岡山大学
Copyright Holders	© 2020 Elsevier B.V.
File Version	author
PubMed ID	32887012
DOI	10.1016/j.scitotenv.2020.140465
Web of Science KeyUT	000568812200013
Related Url	isVersionOf https://doi.org/10.1016/j.scitotenv.2020.140465

Variation of pro‐vasopressin processing in parvocellular and magnocellular neurons in the paraventricular nucleus of the hypothalamus: Evidence from the vasopressin‐related glycopeptide copeptin

FullText URL	fulltext.pdf
Author	Kawakami, Natsuko\| Otubo, Akito\| Maejima, Sho\| Talukder, Ashraf H.\| Satoh, Keita\| Oti, Takumi\| Takanami, Keiko\| Ueda, Yasumasa\| Itoi, Keiichi\| Morris, John F.\| Sakamoto, Tatsuya\| Sakamoto, Hirotaka\|
Keywords	copeptin hypothalamo‐pituitary–adrenal system immunohistochemistry paraventricular nucleus of the hypothalamus processing vasopressin RRID: AB_2722604 RRID: AB_2061966 RRID: AB_2314234 RRID: AB_10013361 RRID: AB_2313960 RRID: AB_2722605 RRID: AB_90782
Published Date	2020-09-06
Publication Title	Journal of Comparative Neurology
Volume	volume529
Issue	issue7
Publisher	Wiley
Start Page	1372
End Page	1390
ISSN	0021-9967
NCID	AA00695917
Content Type	Journal Article
language	English
OAI-PMH Set	岡山大学
Copyright Holders	© 2020 The Authors.
File Version	publisher
PubMed ID	32892351
DOI	10.1002/cne.25026
Web of Science KeyUT	000571267600001
Related Url	isVersionOf https://doi.org/10.1002/cne.25026

Curved-Tip Disposable Injector (OUReP Injector) to Insert Photoelectric Dye-Coupled Polyethylene Film (OUReP) as Retinal Prosthesis into Subretinal Space of Rabbit Eyes

FullText URL	fulltext.pdf
Author	Matsuo, Toshihiko\| matsuo, Chie\| Uchida, Tetsuya\| Yamashita, Koichiro\| Tanaka, Tenu\| Kawakami, Yusuke\| Hitomi, Toshiya\| Taga, Kanji\| Sanada, Tatsuya\| Yamashita, Yusuke\|
Keywords	Dye-coupled thin film retinal prosthesis Curved-tip injector Photoelectric dye Rabbit 25G vitrectomy
Published Date	2020-09-23
Publication Title	Journal of Surgical Techniques and Procedures
Volume	volume4
Issue	issue3
Publisher	Remedy
Start Page	1040
Content Type	Journal Article
language	English
OAI-PMH Set	岡山大学
Copyright Holders	© 2020 Toshihiko Matsuo
File Version	publisher
Official Url	http://www.remedypublications.com/journal-of-surgical-techniques-and-procedures-home.php\|
Related Url	isVersionOf http://www.remedypublications.com/journal-of-surgical-techniques-and-procedures-articles.php?vol=4&&iss=3

Mechanism underlying hippocampal long-term potentiation and depression based on competition between endocytosis and exocytosis of AMPA receptors

FullText URL	fulltext.pdf
Author	Sumi, Tomonari\| Harada, Kouji\|
Keywords	Biophysical models Long-term depression Long-term potentiation
Published Date	2020-09-07
Publication Title	Scientific Reports
Volume	volume10
Issue	issue1
Publisher	Nature
Start Page	14711
ISSN	2045-2322
Content Type	Journal Article
language	English
OAI-PMH Set	岡山大学
Copyright Holders	© The Author(s) 2020
File Version	publisher
PubMed ID	32895399
DOI	10.1038/s41598-020-71528-3
Web of Science KeyUT	000570970200006
Related Url	isVersionOf https://doi.org/10.1038/s41598-020-71528-3

Synthesis and Physicochemical Properties of 2,7-Disubstituted Phenanthro[2,1-b:7,8-b']dithiophenes

FullText URL	fulltext.pdf
Author	Ji, Zhenfei\| Cheng, Zeliang\| Mori, Hiroki\| Nishihara, Yasushi\|
Keywords	phenacene-type compounds thiophene ring cross-coupling alkyl side chains UV-vis absorption p-type organic semiconductors organic field-effect transistor (OFET)
Published Date	2020-08-24
Publication Title	Molecules
Volume	volume25
Issue	issue17
Publisher	MDPI
Start Page	3842
ISSN	1420-3049
Content Type	Journal Article
language	English
OAI-PMH Set	岡山大学
Copyright Holders	© 2020 by the authors.
File Version	publisher
PubMed ID	32847046
DOI	10.3390/molecules25173842
Web of Science KeyUT	000570403100001
Related Url	isVersionOf https://doi.org/10.3390/molecules25173842

Gamma-ray spectra from thermal neutron capture on gadolinium-155 and natural gadolinium

FullText URL	fulltext.pdf
Author	Tanaka, Tomoyuki\| Hagiwara, Kaito\| Gazzola, Enrico\| Ali, Ajmi\| Ou, Iwa\| Sudo, Takashi\| Das, Pretam Kumar\| Reen, Mandeep Singh\| Dhir, Rohit\| Koshio, Yusuke\| Sakuda, Makoto\| Kimura, Atsushi\| Nakamura, Shoji\| Iwamoto, Nobuyuki\| Harada, Hideo\| Collazuol, Gianmaria\| Lorenz, Sebastian\| Wurm, Michael\| Focillon, William\| Gonin, Michel\| Yano, Takatomi\|
Published Date	2020-04-13
Publication Title	Progress of Theoretical and Experimental Physics
Volume	volume2020
Issue	issue4
Publisher	Oxford University Press
Start Page	043D02
ISSN	2050-3911
Content Type	Journal Article
language	English
OAI-PMH Set	岡山大学
Copyright Holders	© The Author(s) 2020.
File Version	publisher
DOI	10.1093/ptep/ptaa015
Web of Science KeyUT	000565930600002
Related Url	isVersionOf https://doi.org/10.1093/ptep/ptaa015

First‐Principles Study of Pressure‐Induced Amorphization of Fe2SiO4 Fayalite

FullText URL	fulltext.pdf
Author	Misawa, Masaaki\| Shimojo, Fuyuki\|
Keywords	amorphous structures density functional theory iron silicate molecular dynamics
Note	This fulltext is available in Aug. 2021.\|
Published Date	2020-08-27
Publication Title	physica status solidi (b)
Volume	volume257
Issue	issue11
Publisher	Wiley
Start Page	2000173
ISSN	0370-1972
NCID	AA12238694
Content Type	Journal Article
language	English
OAI-PMH Set	岡山大学
File Version	author
DOI	10.1002/pssb.202000173
Web of Science KeyUT	000566455800001
Related Url	isVersionOf https://doi.org/10.1002/pssb.202000173

Transcriptomic Analysis of the Kuruma PrawnMarsupenaeus japonicusReveals Possible Peripheral Regulation of the Ovary

FullText URL	fulltext.pdf
Author	Tsutsui, Naoaki\| Kobayashi, Yasuhisa\| Izumikawa, Kouichi\| Sakamoto, Tatsuya\|
Keywords	peptide hormone Marsupenaeus japonicus ovary reproduction transcriptome vitellogenesis
Published Date	2020-08-19
Publication Title	Frontiers in Endocrinology
Volume	volume11
Publisher	Frontiers Media
Start Page	541
ISSN	1664-2392
Content Type	Journal Article
language	English
OAI-PMH Set	岡山大学
Copyright Holders	© 2020 Tsutsui, Kobayashi, Izumikawa and Sakamoto.
File Version	publisher
DOI	10.3389/fendo.2020.00541
Web of Science KeyUT	000566191000001
Related Url	isVersionOf https://doi.org/10.3389/fendo.2020.00541

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