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The Incidence of Desaturation during Anesthesia in Adult and Pediatric Patients: A Retrospective Study
JaLCDOI 10.18926/AMO/56244
FullText URL 72_5_467_n.pdf
Author Vika Fatafehi Hala’ufia Lemoto| Sugimoto, Kentaro| Kanazawa, Tomoyuki| Matsuzaki, Takashi| Morimatsu, Hiroshi|
Abstract We investigated the incidence of desaturation during general anesthesia in preoperatively hypoxic (< 92%), and nonhypoxic (≥ 92%) pediatric (n=1,090) and adult (n=5,138) patients. We plotted the patients’ SpO2 value time-courses and assessed desaturation in 6,228 patients. The crude overall incidence (95%CI) for desaturation was 11.1% (9.4-13.1) in the pediatric patients and 0.9% (0.6-1.2) in the adults. The crude incidence of desaturation in the hypoxic pediatric patients was 2.5 times the risk in the nonhypoxic patients: risk ratio (RR) 2.5 (1.8-3.5), p<0.001. The risk of desaturation in the hypoxic adult patients was 20.1 times the risk in the nonhypoxic adult patients: RR 20.1 (10.3-39.2), p<0.001. When the patients were separately stratified by American Society of Anesthesiologists Physical Status (ASA-PS) and by age, the directly adjusted risk-ratio (RRS) showed that the hypoxic pediatric patients had 1.8 and 1.6 times the risk in the nonhypoxic pediatric patients: ASA-PS adjusted RRS 1.6 (1.8-2.2), p<0.001; age-adjusted RRS 1.8 (1.3-2.5), p<0.001, and the hypoxic adult patients had 13.8 times the risk in the nonhypoxic adult patients: RRS 13.8 (6.9-27.6), p<0.001. A pulse-oximeter check before the start of general anesthesia could ensure timely preparation to avoid intraoperative desaturation.
Keywords desaturation incidence pulse oximetry general anesthesia adult pediatric
Amo Type Original Article
Publication Title Acta Medica Okayama
Published Date 2018-10
Volume volume72
Issue issue5
Publisher Okayama University Medical School
Start Page 467
End Page 478
ISSN 0386-300X
NCID AA00508441
Content Type Journal Article
language English
Copyright Holders CopyrightⒸ 2018 by Okayama University Medical School
File Version publisher
Refereed True
PubMed ID 30369603
Quercetin Attenuates Neuropathic Pain in Rats with Spared Nerve Injury
JaLCDOI 10.18926/AMO/56243
FullText URL 72_5_457.pdf
Author Muto, Noriko| Matsuoka, Yoshikazu| Arakawa, Kyosuke| Kurita, Masako| Omiya, Hiroki| Taniguchi, Arata| Kaku, Ryuji| Morimatsu, Hiroshi|
Abstract Quercetin is a flavonoid widely found in plants and marketed to the public as a supplement. Several studies have reported its effect on glial cells. This study aimed to examine the effect of quercetin on the development of neuropathic pain and the underlying mechanism in a spared nerve injury (SNI) rat model. Male Sprague-Dawley rats randomly assigned to the control or the quercetin group were subjected to SNI of the sciatic nerve. We measured pain behaviors on the hind paw and glial fibrillary acidic protein (GFAP) in the dorsal root ganglion (DRG) and spinal cord. Oral administration of 1% quercetin, begun before surgery, attenuated mechanical allodynia compared to the control group at days 7 and 10 after SNI. On the other hand, established pain was not attenuated in a post-dose group in which quercetin was begun 7 days after SNI. Quercetin inhibited GFAP in the satellite glial cells of the ipsilateral L5 DRG on day 7 compared to the control group. Quercetin suppressed the development of neuropathic pain through a mechanism partly involving the inhibition of satellite glial cells. As its safety is well established, quercetin has great potential for clinical use in pain treatment.
Keywords flavonoid dorsal root ganglion glial fibrillary acidic protein alternative medicine
Amo Type Original Article
Publication Title Acta Medica Okayama
Published Date 2018-10
Volume volume72
Issue issue5
Publisher Okayama University Medical School
Start Page 457
End Page 465
ISSN 0386-300X
NCID AA00508441
Content Type Journal Article
language English
Copyright Holders CopyrightⒸ 2018 by Okayama University Medical School
File Version publisher
Refereed True
PubMed ID 30369602
Clinical Characteristics of Febrile Outpatients : Possible Involvement of Thyroid Dysfunction in Febrile Tachycardia
JaLCDOI 10.18926/AMO/56242
FullText URL 72_5_447.pdf
Author Oka, Kosuke| Hanayama, Yoshihisa| Sato, Asuka| Omura, Daisuke| Yasuda, Miho| Hasegawa, Ko| Obika, Mikako| Otsuka, Fumio|
Abstract We retrospectively analyzed the cases of 148 febrile patients whose body temperature (BT) was ≥ 37.5°C at our hospital. We categorized them into seven groups; those with bacterial and viral infection, nonspecific inflammation, neoplasm, connective tissue disease (CTD), drug-induced disease, and unidentified causes. Our analysis revealed that the patient’s BT at the 1st visit (BT-1st visit) and highest BT during the febrile period (BT-max) differed significantly among all categories except neoplasm. The greatest difference between BT-1st visit and BT-max was highest in the CTD group (1.5°C). Positive correlations of heart rate and C-reactive protein (CRP) level with BT-max and a negative correlation between serum sodium level with BT-max were uncovered. The serum thyroid-stimulating hormone (TSH) level and the ratio of TSH/free thyroxine were negatively correlated with BT-max, especially in the viral infection group, suggesting the existence of occult thyrotoxicosis in accord with a febrile condition, possibly leading to febrile tachycardia. A febrile gap between BT-1st visit and BT-max (except in the neoplasm group) was shown, in which BT-max was correlated with thyroid function. Clinicians should recognize the fluctuation of BT when diagnosing febrile patients, and tachycardia in such febrile patients may be, at least in part, associated with subclinical thyroid dysfunction.
Keywords body temperature C-reactive protein fever of unknown origin tachycardia thyroid dysfunction
Amo Type Original Article
Publication Title Acta Medica Okayama
Published Date 2018-10
Volume volume72
Issue issue5
Publisher Okayama University Medical School
Start Page 447
End Page 456
ISSN 0386-300X
NCID AA00508441
Content Type Journal Article
language English
Copyright Holders CopyrightⒸ 2018 by Okayama University Medical School
File Version publisher
Refereed True
PubMed ID 30369601
奥付
FullText URL bfsc_039_colophon.pdf
Author 岡山大学農学部附属山陽圏フィールド科学センター |
Publication Title Bulletin of the Field Science Center, Faculty of Agriculture, Okayama University
Published Date 2017-04-01
Volume volume39
ISSN 0910-8742
language Japanese
Copyright Holders 岡山大学農学部
File Version publisher
センター報告投稿要領
FullText URL bfsc_039_059.pdf
Author 岡山大学農学部附属山陽圏フィールド科学センター |
Publication Title Bulletin of the Field Science Center, Faculty of Agriculture, Okayama University
Published Date 2017-04-01
Volume volume39
Start Page 59
End Page 59
ISSN 0910-8742
language Japanese
Copyright Holders 岡山大学農学部
File Version publisher
資料 : 2016年度
FullText URL bfsc_039_055_058.pdf
Author 岡山大学農学部附属山陽圏フィールド科学センター |
Publication Title Bulletin of the Field Science Center, Faculty of Agriculture, Okayama University
Published Date 2017-04-01
Volume volume39
Start Page 55
End Page 58
ISSN 0910-8742
language Japanese
Copyright Holders 岡山大学農学部
File Version publisher
運営 : 2016年度
FullText URL bfsc_039_015_054.pdf
Author 岡山大学農学部附属山陽圏フィールド科学センター |
Publication Title Bulletin of the Field Science Center, Faculty of Agriculture, Okayama University
Published Date 2017-04-01
Volume volume39
Start Page 15
End Page 54
ISSN 0910-8742
language Japanese
Copyright Holders 岡山大学農学部
File Version publisher
地域連携 : 2016年度
FullText URL bfsc_039_013_014.pdf
Author 岡山大学農学部附属山陽圏フィールド科学センター |
Publication Title Bulletin of the Field Science Center, Faculty of Agriculture, Okayama University
Published Date 2017-04-01
Volume volume39
Start Page 13
End Page 14
ISSN 0910-8742
language Japanese
Copyright Holders 岡山大学農学部
File Version publisher
試験研究 : 2016年度
FullText URL bfsc_039_009_012.pdf
Author 岡山大学農学部附属山陽圏フィールド科学センター |
Publication Title Bulletin of the Field Science Center, Faculty of Agriculture, Okayama University
Published Date 2017-04-01
Volume volume39
Start Page 9
End Page 12
ISSN 0910-8742
language Japanese
Copyright Holders 岡山大学農学部
File Version publisher
教育 : 2016年度
FullText URL bfsc_039_001_007.pdf
Author 岡山大学農学部附属山陽圏フィールド科学センター |
Publication Title Bulletin of the Field Science Center, Faculty of Agriculture, Okayama University
Published Date 2017-04-01
Volume volume39
Start Page 1
End Page 7
ISSN 0910-8742
language Japanese
Copyright Holders 岡山大学農学部
File Version publisher
目次
FullText URL bfsc_039_index.pdf
Author 岡山大学農学部附属山陽圏フィールド科学センター |
Publication Title Bulletin of the Field Science Center, Faculty of Agriculture, Okayama University
Published Date 2017-04-01
Volume volume39
ISSN 0910-8742
language Japanese
Copyright Holders 岡山大学農学部
File Version publisher
序
FullText URL bfsc_039_pre.pdf
Author Yoshida, Yuichi|
Publication Title Bulletin of the Field Science Center, Faculty of Agriculture, Okayama University
Published Date 2017-04-01
Volume volume39
ISSN 0910-8742
language Japanese
Copyright Holders 岡山大学農学部
File Version publisher
表紙
FullText URL bfsc_039_cover.pdf
Author 岡山大学農学部附属山陽圏フィールド科学センター |
Publication Title Bulletin of the Field Science Center, Faculty of Agriculture, Okayama University
Published Date 2017-04-01
Volume volume39
ISSN 0910-8742
language Japanese
Copyright Holders 岡山大学農学部
File Version publisher
配当所得課税のあり方 : 法人税との関係から
Title Alternative The Concept of Dividend in Japanese Income Tax : Past, Now and Future;
FullText URL ronsyu_74_217.pdf
Author KOZUKA, Masahiro|
Published Date 2018-09-20
Publication Title 日税研論集
Issue issue74
Publisher 日本税務研究センター
Start Page 217
End Page 249
ISSN 0912-9685
NCID AN10032022
Content Type Journal Article
language Japanese
OAI-PMH Set 岡山大学
File Version publisher
裏表紙・英文目次
FullText URL olr_021_contents_eng.pdf
Author 岡山大学大学院法務研究科|
Publication Title Okayama Law Review
Published Date 2018-09
Volume volume21
ISSN 1881-1485
language Japanese
File Version publisher
奥付
FullText URL olr_021_colophon.pdf
Author 岡山大学大学院法務研究科|
Publication Title Okayama Law Review
Published Date 2018-09
Volume volume21
ISSN 1881-1485
language Japanese
File Version publisher
執筆者紹介
FullText URL olr_021_author.pdf
Author 岡山大学大学院法務研究科|
Publication Title Okayama Law Review
Published Date 2018-09
Volume volume21
ISSN 1881-1485
language Japanese
File Version publisher
散骨規制条例と葬送の自由・死者の尊厳
JaLCDOI 10.18926/OLR/56227
Title Alternative How can Local Public Entities Constitutionally Regulate the Dispersion of Ashes of the Dead？
FullText URL olr_021_111_128.pdf
Author Tajika, Hajime|
Publication Title Okayama Law Review
Published Date 2018-09
Volume volume21
Start Page 111
End Page 128
ISSN 1881-1485
language Japanese
File Version publisher
NAID 120006528318
弁護士のキャリアと国税審判官のお仕事
JaLCDOI 10.18926/OLR/56226
Title Alternative Appeals Judge for National Tax Tribunal as Lawyer’s Carrer
FullText URL olr_021_083_110.pdf
Author Nakai, Akira|
Publication Title Okayama Law Review
Published Date 2018-09
Volume volume21
Start Page 83
End Page 110
ISSN 1881-1485
language Japanese
File Version publisher
NAID 120006528317
国税不服申立制度の概要
JaLCDOI 10.18926/OLR/56225
Title Alternative Overview of National Tax Appeal System
FullText URL olr_021_069_082.pdf
Author Okuda, Yoshihiko|
Publication Title Okayama Law Review
Published Date 2018-09
Volume volume21
Start Page 69
End Page 82
ISSN 1881-1485
language Japanese
File Version publisher
NAID 120006528316
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