| ID | 15849 |
| Eprint ID | 15849
|
| FullText URL | |
| Title Alternative | Studies of lipid metabolism in cultured smooth muscle cells.Part I. Effect of antioxidants on cell proliferation and lipid peroxide formation.
|
| Author |
Demiya, Michitaka
|
| Abstract | The effects of antioxidants on cell proliferation and lipid peroxide formation of cultured aortic smooth muscle cells obtained from normal, hypercholesterolemic and aged rabbits were studied in vitro.α-Tocopherol and coenzyme Q(10) were used as antioxidants.The lipid peroxide content of cells was generated in a time dependent manner with cell proliferation, it remained within the cells and did not accumulate in the media.α-Tocopherol promoted cell proliferation and suppressed the intracellular lipid peroxide formation expressed in terms of DNA content.These effects were significant only in HL-SMC, and were not significant in NR-SMC or Aged-SMC. Coenzyme Q(10) did not effect cell proliferation or lipid peroxide formation.
|
| Keywords | 平滑筋細胞
過酸化脂質
α-トコフェロール
コエンザイムQ(10)
抗酸化剤
|
| Published Date | 1988
|
| Publication Title |
岡山医学会雑誌
|
| Publication Title Alternative | Journal of Okayama Medical Association
|
| Volume | volume100
|
| Issue | issue1-2
|
| Publisher | 岡山医学会
|
| Publisher Alternative | Okayama Medical Association
|
| Start Page | 37
|
| End Page | 45
|
| ISSN | 0030-1558
|
| NCID | AN00032489
|
| Content Type |
Journal Article
|
| Official Url | https://www.jstage.jst.go.jp/article/joma1947/100/1-2/100_1-2_37/_article/-char/ja/
|
| Related Url | http://www.okayama-u.ac.jp/user/oma/index.html
|
| language |
Japanese
|
| Copyright Holders | 岡山医学会
|
| File Version | publisher
|
| Refereed |
True
|
| Eprints Journal Name | joma
|
