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Author Watanabe, Tomofumi| Ishino, Takamasa| Ueda, Youki| Nagasaki, Joji| Sadahira, Takuya| Dansako, Hiromichi| Araki, Motoo| Togashi, Yosuke|
Keywords antibody-dependent cell cytotoxicity cytotoxic T-lymphocyte-associated antigen 4 immune checkpoint inhibitors regulatory T cell renal cell carcinoma
Published Date 2023-02-10
Publication Title Cancer Science
Publisher Wiley
ISSN 1347-9032
Content Type Journal Article
language English
OAI-PMH Set 岡山大学
Copyright Holders © 2023 The Authors.
File Version publisher
PubMed ID 36762794
DOI 10.1111/cas.15756
Web of Science KeyUT 000940385500001
Related Url isVersionOf https://doi.org/10.1111/cas.15756
FullText URL fulltext.pdf
Author Tanaka, Hiroyoshi Y.| Nakazawa, Takuya| Enomoto, Atsushi| Masamune, Atsushi| Kano, Mitsunobu R.|
Keywords pancreatic cancer tumor microenvironment nanomedicine fibrosis extracellular matrix fibroblast
Published Date 2023-01-24
Publication Title Cancers
Volume volume15
Issue issue3
Publisher MDPI
Start Page 724
ISSN 2072-6694
Content Type Journal Article
language English
OAI-PMH Set 岡山大学
Copyright Holders © 2023 by the authors.
File Version publisher
PubMed ID 36765684
DOI 10.3390/cancers15030724
Web of Science KeyUT 000929314700001
Related Url isVersionOf https://doi.org/10.3390/cancers15030724
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Author Huang, Rongsheng| Yamamoto, Takahiro| Nakata, Eiji| Ozaki, Toshifumi| Kurozumi, Kazuhiko| Wei, Fanyan| Tomizawa, Kazuhito| Fujimura, Atsushi|
Keywords cancer stem-like cells CG-rich 5'UTR eIF4F complex CDKAL1 SALL2
Published Date 2023-02-14
Publication Title Advanced Science
Publisher Wiley
Start Page 2206542
ISSN 2198-3844
Content Type Journal Article
language English
OAI-PMH Set 岡山大学
Copyright Holders © 2023 The Authors.
File Version publisher
PubMed ID 36786012
DOI 10.1002/advs.202206542
Web of Science KeyUT 000930130700001
Related Url isVersionOf https://doi.org/10.1002/advs.202206542
JaLCDOI 10.18926/AMO/64366
FullText URL 77_1_81.pdf
Author Tomita, Koji| Iguchi, Toshihiro| Matsui, Yusuke| Uka, Mayu| Nakata, Eiji| Hiraki, Takao|
Abstract Osteoid osteoma (OO) is a benign bone tumor that presents with nocturnal pain. Computed tomography (CT)- guided radiofrequency ablation (RFA) has been widely performed for OO, and major adverse events post-RFA are rare. We report a case of OO in the left navicular bone of a 15-year-old male. He underwent RFA for OO, and the pain improved temporarily. At the 1-month follow-up, the patient complained of left foot pain, and a CT examination revealed a fracture of the ablated navicular bone. Fractures are rare but must be taken into account after bone RFA.
Keywords osteoid osteoma radiofrequency ablation navicular bone fracture
Amo Type Case Report
Publication Title Acta Medica Okayama
Published Date 2023-02
Volume volume77
Issue issue1
Publisher Okayama University Medical School
Start Page 81
End Page 84
ISSN 0386-300X
NCID AA00508441
Content Type Journal Article
language English
Copyright Holders Copyright Ⓒ 2023 by Okayama University Medical School
File Version publisher
Refereed True
PubMed ID 36849150
Web of Science KeyUT 000952973200002
FullText URL fulltext20230207-4.pdf
Author Kubota, Satoshi| Kawaki, Harumi| Perbal, Bernard| Takigawa, Masaharu| Kawata, Kazumi| Hattori, Takako| Nishida, Takashi|
Keywords CCN family CCN3 cartilage chondrocytes energy metabolism
Note This version of the article has been accepted for publication, after peer review (when applicable) and is subject to Springer Nature’s AM terms of use, but is not the Version of Record and does not reflect post-acceptance improvements, or any corrections. The Version of Record is available online at: http://dx.doi.org/10.1007/s12079-023-00723-4| This full-text file will be available in Feb. 2024.|
Published Date 2023-02-06
Publication Title Journal of Cell Communication and Signaling
Volume volume17
Issue issue2
Publisher Springer Science and Business Media LLC
Start Page 353
End Page 359
ISSN 1873-9601
Content Type Journal Article
language English
OAI-PMH Set 岡山大学
Copyright Holders © The International CCN Society 2023
File Version author
PubMed ID 36745317
DOI 10.1007/s12079-023-00723-4
Web of Science KeyUT 000927462300001
Related Url isVersionOf https://doi.org/10.1007/s12079-023-00723-4
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Author Akezaki, Yoshiteru| Nakata, Eiji| Kikuuchi, Masato| Tominaga, Ritsuko| Kurokawa, Hideaki| Okamoto, Masaki| Ozaki, Toshifumi| Aogi, Kenjiro| Ohsumi, Shozo| Sugihara, Shinsuke|
Keywords breast cancer elderly comorbidity upper-limb function rehabilitation
Published Date 2023-01-04
Publication Title Current Oncology
Volume volume30
Issue issue1
Publisher MDPI
Start Page 673
End Page 680
ISSN 1198-0052
Content Type Journal Article
language English
OAI-PMH Set 岡山大学
Copyright Holders © 2023 by the authors.
File Version publisher
PubMed ID 36661701
DOI 10.3390/curroncol30010052
Web of Science KeyUT 000914388100001
Related Url isVersionOf https://doi.org/10.3390/curroncol30010052
FullText URL fulltext20230125-1.pdf figures20230125-1.pdf tables20230125-1.pdf
Author Xue, Haowei| Furumatsu, Takayuki| Hiranaka, Takaaki| Kintaka, Keisuke| Higashihara, Naohiro| Tamura, Masanori| Zhang, Ximing| Ozaki, Toshifumi|
Keywords Medial meniscus Pullout repair Meniscal extrusion Meniscal root tear Suture anchor Three-dimensional magnetic resonance imaging
Note This version of the article has been accepted for publication, after peer review (when applicable) and is subject to Springer Nature’s AM terms of use, but is not the Version of Record and does not reflect post-acceptance improvements, or any corrections. The Version of Record is available online at: http://dx.doi.org/10.1007/s00264-022-05660-2| This full-text file will be available in Dec. 2023.|
Published Date 2022-12-28
Publication Title International Orthopaedics
Volume volume47
Issue issue10
Publisher Springer Science and Business Media LLC
Start Page 2391
End Page 2400
ISSN 0341-2695
NCID AA0068148X
Content Type Journal Article
language English
OAI-PMH Set 岡山大学
Copyright Holders © The Author(s) under exclusive licence to SICOT aisbl 2022
File Version author
PubMed ID 36575357
DOI 10.1007/s00264-022-05660-2
Web of Science KeyUT 000904067500001
Related Url isVersionOf https://doi.org/10.1007/s00264-022-05660-2
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Author Hirose, Kazuki| Kuwahara, Miho| Nakata, Eiji| Tetsunaga, Tomonori| Yamada, Kazuki| Saiga, Kenta| Takigawa, Masaharu| Ozaki, Toshifumi| Kubota, Satoshi| Hattori, Takako|
Keywords hip osteoarthritis cartilage cellular communication network factor 3 (CCN3) senescence-associatedsecretory phenotype (SASP) p16 ADAMTA4/5 IL-6 TNFa aging Mankinscore weight-bearing non-weight-bearing
Published Date 2022-12-04
Publication Title International Journal Of Molecular Sciences
Volume volume23
Issue issue23
Publisher MDPI
Start Page 15311
ISSN 1422-0067
Content Type Journal Article
language English
OAI-PMH Set 岡山大学
Copyright Holders © 2022 by the authors.
File Version publisher
PubMed ID 36499638
DOI 10.3390/ijms232315311
Web of Science KeyUT 000897995800001
Related Url isVersionOf https://doi.org/10.3390/ijms232315311
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Author Nakata, Kentaro| Okazaki, Mikio| Sakaue, Tomohisa| Kinoshita, Rie| Komoda, Yuhei| Shimizu, Dai| Yamamoto, Haruchika| Tanaka, Shin| Suzawa, Ken| Shien, Kazuhiko| Miyoshi, Kentaroh| Yamamoto, Hiromasa| Ohara, Toshiaki| Sugimoto, Seiichiro| Yamane, Masaomi| Matsukawa, Akihiro| Sakaguchi, Masakiyo| Toyooka, Shinichi|
Keywords ischemia reperfusion injury S100A8/A9 lung transplantation damage-associated molecule patterns
Published Date 2022-11-10
Publication Title Bioengineering
Volume volume9
Issue issue11
Publisher MDPI
Start Page 673
ISSN 2306-5354
Content Type Journal Article
language English
OAI-PMH Set 岡山大学
Copyright Holders © 2022 by the authors.
File Version publisher
PubMed ID 36354584
DOI 10.3390/bioengineering9110673
Web of Science KeyUT 000880897200001
Related Url isVersionOf https://doi.org/10.3390/bioengineering9110673
JaLCDOI 10.18926/AMO/64114
FullText URL 76_6_645.pdf
Author Tada, Katsuhiko| Miyagi, Yasunari| Komatsu, Reina| Okimoto, Naoki| Tsukahara, Saya| Tateishi, Yoko| Ooka, Naomi| Yoshida, Mizuho| Kumazawa, Kazumasa|
Abstract We used biomathematics to describe and compare cerebellar growth in normally developing and trisomy 18 Japanese fetuses. This retrospective study included 407 singleton pregnancies with fetuses at 14-39 weeks of gestation and 33 fetuses with trisomy 18 at 17-35 weeks. We used ultrasonography to measure fetal transverse cerebellar diameter (TCD) and anteroposterior cerebellar diameter (APCD). We hypothesized that cerebellar growth is proportional to cerebellar length at any given time point. We determined the formula L(t) ≒Keat+r, where e is Napier’s number, t is time, L is cerebellar length, and a, K, and r are constants. We then obtained regression functions for each TCD and APCD in all fetuses. The regression equations for TCD and APCD values in normal fetuses, expressed as exponential functions, were TCD(t)=27.85e0.02788t−28.62 (mm) (adjusted R2=0.997), and APCD(t)=324.29e0.00286t−322.62 (mm) (adjusted R2=0.995). These functions indicated that TCD and APCD grew at constant rates of 2.788%/week and 0.286%/week, respectively, throughout gestation. TCD (0.0153%/week) and APCD (0.000430%/week) grew more slowly in trisomy 18 fetuses. This study demonstrates the potential of biomathematics in clinical research and may aid in biological understanding of fetal cerebellar growth.
Keywords biomathematics cerebellum fetus trisomy 18 syndrome ultrasonography
Amo Type Original Article
Publication Title Acta Medica Okayama
Published Date 2022-12
Volume volume76
Issue issue6
Publisher Okayama University Medical School
Start Page 645
End Page 650
ISSN 0386-300X
NCID AA00508441
Content Type Journal Article
language English
Copyright Holders Copyright Ⓒ 2022 by Okayama University Medical School
File Version publisher
Refereed True
PubMed ID 36549766
Web of Science KeyUT 000905195100004
FullText URL K0006703_abstract_review.pdf K0006703_summary.pdf K0006703_fulltext.pdf
Author FUJIHARA, Miwa|
Published Date 2022-09-22
Content Type Thesis or Dissertation
Grant Number 甲第6703号
Granted Date 2022-09-22
Thesis Type Doctor of Philosophy in Medical Science
Grantor 岡山大学
language English
Copyright Holders © 2021 by the authors.
JaLCDOI 10.18926/AMO/64024
FullText URL 76_5_489.pdf
Author Matsumoto, Yuji| Ichikawa, Tomotsugu| Kurozumi, Kazuhiko| Date, Isao|
Abstract Glioblastoma (GBM) is a fatal primary malignant brain tumor in adults. Despite decades of research, the prognosis for GBM patients is still disappointing. One major reason for the intense therapeutic resistance of GBM is inter- and intra-tumor heterogeneity. GBM-intrinsic transcriptional profiling has suggested the presence of at least three subtypes of GBM: the proneural, classic, and mesenchymal subtypes. The mesenchymal subtype is the most aggressive, and patients with the mesenchymal subtype of primary and recurrent tumors tend to have a worse prognosis compared with patients with the other subtypes. Furthermore, GBM can shift from other subtypes to the mesenchymal subtype over the course of disease progression or recurrence. This phenotypic transition is driven by diverse tumor-intrinsic molecular mechanisms or microenvironmental factors. Thus, better understanding of the plastic nature of mesenchymal transition in GBM is pivotal to developing new therapeutic strategies. In this review, we provide a comprehensive overview of the current understanding of the elements involved in the mesenchymal transition of GBM and discuss future perspectives.
Keywords glioma glioblastoma mesenchymal subtype mesenchymal transition heterogeneity
Amo Type Review
Publication Title Acta Medica Okayama
Published Date 2022-10
Volume volume76
Issue issue5
Publisher Okayama University Medical School
Start Page 489
End Page 502
ISSN 0386-300X
NCID AA00508441
Content Type Journal Article
language English
Copyright Holders Copyright Ⓒ 2022 by Okayama University Medical School
File Version publisher
Refereed True
PubMed ID 36352795
Web of Science KeyUT 000884907100001
FullText URL fulltext.pdf
Author Toyama, Naoki| Ekuni, Daisuke| Yokoi, Aya| Fukuhara, Daiki| Islam, Md Monirul| Sawada, Nanami| Nakashima, Yukiho| Nakahara, Momoko| Sumita, Ichiro| Morita, Manabu|
Keywords oral microbiome elderly people diversity bacteria non-severe periodontal condition
Published Date 2022-10-06
Publication Title Frontiers In Cellular And Infection Microbiology
Volume volume12
Publisher Frontiers Media SA
Start Page 957890
ISSN 2235-2988
Content Type Journal Article
language English
OAI-PMH Set 岡山大学
Copyright Holders © 2022 Toyama, Ekuni, Yokoi, Fukuhara, Islam, Sawada, Nakashima, Nakahara, Sumita and Morita.
File Version publisher
PubMed ID 36275030
DOI 10.3389/fcimb.2022.957890
Web of Science KeyUT 000874245900001
Related Url isVersionOf https://doi.org/10.3389/fcimb.2022.957890
FullText URL fulltext.pdf
Author Shigehiro, Tsukasa| Ueno, Maho| Kijihira, Mayumi| Takahashi, Ryotaro| Umemura, Chiho| Taha, Eman A.| Kurosaka, Chisaki| Asayama, Megumi| Murakami, Hiroshi| Satoh, Ayano| Nakamura, Yoshimasa| Futami, Junichiro| Masuda, Junko|
Keywords breast cancer cells dendritic cells mesenteric lymph node myeloid-derived suppressor cells
Published Date 2022-09-20
Publication Title International Journal Of Molecular Sciences
Volume volume23
Issue issue19
Publisher MDPI
Start Page 11035
ISSN 1422-0067
Content Type Journal Article
language English
OAI-PMH Set 岡山大学
Copyright Holders © 2022 by the authors.
File Version publisher
PubMed ID 36232335
DOI 10.3390/ijms231911035
Web of Science KeyUT 000867767200001
Related Url isVersionOf https://doi.org/10.3390/ijms231911035
FullText URL fulltext20230112-5.pdf
Author Matsuo, Toshihiko| Tanaka, Takehiro| Omote, Rika| Okada, Toshiaki| Notohara, Kenji| Okada, Kazuya|
Published Date 2022
Publication Title Journal of Clinical and Experimental Hematopathology
Volume volume62
Issue issue4
Publisher Japanese Society for Lymphoreticular Tissue Research
Start Page 226
End Page 237
ISSN 1346-4280
Content Type Journal Article
language English
OAI-PMH Set 岡山大学
Copyright Holders © 2022 The Japanese Society for Lymphoreticular Tissue Research
File Version publisher
PubMed ID 36171112
DOI 10.3960/jslrt.22015
Related Url isVersionOf https://doi.org/10.3960/jslrt.22015
FullText URL fulltext20221017-2.pdf fig2221017-2.pdf tables20221017-2.pdf
Author Furumatsu, Takayuki| Miyazawa, Shinichi| Kodama, Yuya| Kamatsuki, Yusuke| Okazaki, Yoshiki| Hiranaka, Takaaki| Okazaki, Yuki| Kintaka, Keisuke| Ozaki, Toshifumi|
Keywords Medial meniscus Posterior root tear MMPRT Transtibial pullout repair Clinical outcome
Note © 2022 Elsevier B.V. This manuscript version is made available under the CC-BY-NC-ND 4.0 License. http://creativecommons.org/licenses/by-nc-nd/4.0/. This is the accepted manuscript version. The formal published version is available at [https://doi.org/10.1016/j.knee.2022.08.010] .| This fulltext is available in Sep. 2023.|
Published Date 2022-10
Publication Title The Knee
Volume volume38
Publisher Elsevier BV
Start Page 141
End Page 147
ISSN 0968-0160
NCID AA11534443
Content Type Journal Article
language English
OAI-PMH Set 岡山大学
Copyright Holders © 2022 Elsevier B.V.
File Version author
PubMed ID 36058121
DOI 10.1016/j.knee.2022.08.010
Web of Science KeyUT 000863705700003
Related Url isVersionOf https://doi.org/10.1016/j.knee.2022.08.010
FullText URL fulltext.pdf
Author Wang, Dengli| Ousaka, Daiki| Qiao, Handong| Wang, Ziyi| Zhao, Kun| Gao, Shangze| Liu, Keyue| Teshigawara, Kiyoshi| Takada, Kenzo| Nishibori, Masahiro|
Keywords intracerebral hemorrhage HMGB1 antibody therapy non-human primate
Published Date 2022-09-23
Publication Title Cells
Volume volume11
Issue issue19
Publisher MDPI
Start Page 2970
ISSN 2073-4409
Content Type Journal Article
language English
OAI-PMH Set 岡山大学
Copyright Holders © 2022 by the authors.
File Version publisher
PubMed ID 36230933
DOI 10.3390/cells11192970
Web of Science KeyUT 000866922400001
Related Url isVersionOf https://doi.org/10.3390/cells11192970
JaLCDOI 10.18926/AMO/63893
FullText URL 76_4_391.pdf
Author Habu, Hiroshi| Mitsuhashi, Toshiharu| Tokinobu, Akiko| Yorifuji, Takashi| Takao, Soshi|
Abstract Tanden breathing, an ancient health technique, involves expiratory abdominal pressure breathing is practiced in Japan. In this study we examined the ability of Tanden breathing to relieve constipation. The study was designed as a stratified-block randomized controlled trial enrolling 20 participants. Nineteen were female and one was male, none were elderly. During the 6-week intervention period, the participants performed video-guided Tanden breathing about 10 min once day. We evaluated constipation using the Constipation Assessment Scale (CAS). There were significant differences in the mean CAS score between time points (baseline, 3 weeks after baseline, 6 weeks after baseline), groups (intervention and control), and their interaction (time×group) using repeated-measures analysis of variance. The control group showed no change in the mean CAS score; the mean CAS scores of the intervention group changed from 7.2 at baseline to 3.9 at 3 weeks and 3.1 at 6 weeks after baseline. A regression analysis of the difference in the mean CAS between baseline and 6 weeks later showed that the CAS of the intervention group was 4.3 points lower than that of the control group (95% confidence interval, 2.5-6.1). The results suggested that Tanden breathing is effective in relieving constipation among young women.
Keywords Tanden breathing Dantian breathing exercises constipation mind−body therapy
Amo Type Original Article
Publication Title Acta Medica Okayama
Published Date 2022-08
Volume volume76
Issue issue4
Publisher Okayama University Medical School
Start Page 391
End Page 398
ISSN 0386-300X
NCID AA00508441
Content Type Journal Article
language English
Copyright Holders Copyright Ⓒ 2022 by Okayama University Medical School
File Version publisher
Refereed True
PubMed ID 36123153
Web of Science KeyUT 000882167300001
FullText URL fulltext.pdf
Author Nara, Shigetoshi| Fujii, Hiroshi| Tsukada, Hiromichi| Tsuda, Ichiro|
Published Date 2022-08-19
Publication Title Scientific Reports
Volume volume12
Issue issue1
Publisher Nature Portfolio
Start Page 14172
ISSN 2045-2322
Content Type Journal Article
language English
OAI-PMH Set 岡山大学
Copyright Holders © The Author(s) 2022
File Version publisher
PubMed ID 35986200
DOI 10.1038/s41598-022-18313-6
Web of Science KeyUT 000842561700031
Related Url isVersionOf https://doi.org/10.1038/s41598-022-18313-6
FullText URL fulltext20220830-4.pdf CMT2Z Figure NCN revise.tif CMT2Z Table NCN revise.tif
Author Nomura, Emi| Tadokoro, Koh| Sasaki, Ryo| Nakata, Yumi| Nakano, Yumiko| Yunoki, Taijun| Takemoto, Mami| Morihara, Ryuta| Ando, Masahiro| Takashima, Hiroshi| Yamashita, Toru|
Keywords Charcot-Marie-Tooth disease type 2Z MORC2 retinitis pigmentosa
Note This is the peer reviewed version of the following article: [Nomura, E, Tadokoro, K, Sasaki, R, et al. Japanese case of Charcot–Marie–Tooth disease type 2Z with severe retinitis pigmentosa. Neurol Clin Neurosci. 2022; 10: 266-268. doi: 10.1111/ncn3.12660], which has been published in final form at [https://doi.org/10.1111/ncn3.12660]. This article may be used for non-commercial purposes in accordance with Wiley Terms and Conditions for Use of Self-Archived Versions. This article may not be enhanced, enriched or otherwise transformed into a derivative work, without express permission from Wiley or by statutory rights under applicable legislation. Copyright notices must not be removed, obscured or modified. The article must be linked to Wiley’s version of record on Wiley Online Library and any embedding, framing or otherwise making available the article or pages thereof by third parties from platforms, services and websites other than Wiley Online Library must be prohibited.|
Published Date 2022-08-15
Publication Title Neurology and Clinical Neuroscience
Volume volume10
Issue issue5
Publisher Wiley
Start Page 266
End Page 268
ISSN 2049-4173
Content Type Journal Article
language English
OAI-PMH Set 岡山大学
Copyright Holders © 2022 Japanese Society of Neurology and John Wiley & Sons Australia, Ltd.
File Version author
DOI 10.1111/ncn3.12660
Web of Science KeyUT 000843400700001
Related Url isVersionOf https://doi.org/10.1111/ncn3.12660