result 508 件
FullText URL | fulltext.pdf |
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Author | Sato, Hiroki| Nakamura, Takao| |
Keywords | cardiac surgery ultrasonography muscle quality phase angle electrical impedance myography |
Published Date | 2021-12-04 |
Publication Title | Cureus Journal Of Medical Science |
Volume | volume13 |
Issue | issue12 |
Publisher | Cureus Inc. |
Start Page | e20166 |
ISSN | 2168-8184 |
Content Type | Journal Article |
language | English |
OAI-PMH Set | 岡山大学 |
Copyright Holders | © 2021 Sato et al. |
File Version | publisher |
PubMed ID | 34881132 |
DOI | 10.7759/cureus.20166 |
Web of Science KeyUT | 000728580100020 |
Related Url | isVersionOf https://doi.org/10.7759/cureus.20166 |
FullText URL | fulltext.pdf |
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Author | Takaya, Yoichi| Nakamura, Kazufumi| Nakayama, Rie| Ohtsuka, Hiroaki| Amioka, Naofumi| Kondo, Megumi| Akazawa, Kaoru| Ohno, Yuko| Ichikawa, Keishi| Saito, Yukihiro| Akagi, Satoshi| Yoshida, Masashi| Miyoshi, Toru| Ito, Hiroshi| |
Published Date | 2021-11-24 |
Publication Title | Scientific Reports |
Volume | volume11 |
Issue | issue1 |
Publisher | Nature Portfolio |
Start Page | 22812 |
ISSN | 2045-2322 |
Content Type | Journal Article |
language | English |
OAI-PMH Set | 岡山大学 |
Copyright Holders | © The Author(s) 2021 |
File Version | publisher |
PubMed ID | 34819579 |
DOI | 10.1038/s41598-021-02271-6 |
Web of Science KeyUT | 000722365800023 |
Related Url | isVersionOf https://doi.org/10.1038/s41598-021-02271-6 |
FullText URL | fulltext.pdf |
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Author | Nakashima, Mitsutaka| Miyoshi, Toru| Ejiri, Kentaro| Kihara, Hajime| Hata, Yoshiki| Nagano, Toshihiko| Takaishi, Atsushi| Toda, Hironobu| Nanba, Seiji| Nakamura, Yoichi| Akagi, Satoshi| Sakuragi, Satoru| Minagawa, Taro| Kawai, Yusuke| Nishii, Nobuhiro| Fuke, Soichiro| Yoshikawa, Masaki| Nakamura, Kazufumi| Ito, Hiroshi| MUSCAT-HF Study Investigators| |
Keywords | Estimated plasma volume Heart failure with preserved ejection fraction Luseogliflozin Sodium glucose co-transporter 2 inhibitors Voglibose |
Published Date | 2021-11-03 |
Publication Title | Esc Heart Failure |
Publisher | Wiley Periodicals, Inc |
ISSN | 2055-5822 |
Content Type | Journal Article |
language | English |
OAI-PMH Set | 岡山大学 |
Copyright Holders | © 2021 The Authors. |
File Version | publisher |
DOI | 10.1002/ehf2.13683 |
Web of Science KeyUT | 000714002000001 |
Related Url | isVersionOf https://doi.org/10.1002/ehf2.13683 |
JaLCDOI | 10.18926/AMO/62806 |
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FullText URL | 75_6_677.pdf |
Author | Tani Kazumasa| Mitsui, Takashi| Mishima, Sakurako| Ohira, Akiko| Maki, Jota| Eto, Eriko| Hayata, Kei| Nakamura, Keiichiro| Masuyama, Hisashi| |
Abstract | Extravillous trophoblast (EVT) invasion is important for embryo implantation, placental development, and successful remodeling of the uterine spiral artery. Endocrine gland derived-vascular endothelial growth factor (EG-VEGF) and matrix metalloproteinases (MMPs) are implicated in EVT invasion; however, the high con-centrations found in pregnancy pathologies have not been investigated in non-tumor trophoblasts. The roles of EG-VEGF, prokineticin receptors (PROKR1/2), MMP-2, and MMP-9 in EVT invasion during spiral artery remodeling were evaluated using human EVT from HTR-8/SVneo cell lines. The expression of MMP-2, MMP-9, and mitogen-activated protein kinase (MAPK), and Akt pathways in HTR-8/SVneo cells treated with recom-binant EG-VEGF alongside anti-PROKR1 and/or anti-PROKR2 antibodies was evaluated using quantitative reverse transcription-PCR and western blotting. Wound-healing and cell invasion assays were performed to assess the migration and invasion of these treated cells. Interestingly, 20 nM EG-VEGF activated ERK1/2 sig-naling and upregulated MMP-2 and MMP-9. This effect was suppressed by anti-PROKR2 antibody via ERK1/2 downregulation. Anti-PROKR2 antibody inhibited the migration and invasion of EG-VEGF-stimulated HTR-8/SVneo cells. Elevated concentrations of EG-VEGF enhance EVT invasion in a human trophoblast cell line by upregulating MMP-2 and MMP-9 via PROKR2. These new insights into the regulation of epithelial cell invasion may help in developing therapeutic interventions for placental-related diseases during pregnancy. |
Keywords | endocrine gland-derived vascular endothelial growth factor prokineticin extravillous trophoblast matrix metalloproteinase obstetric diseases |
Amo Type | Original Article |
Publication Title | Acta Medica Okayama |
Published Date | 2021-12 |
Volume | volume75 |
Issue | issue6 |
Publisher | Okayama University Medical School |
Start Page | 677 |
End Page | 684 |
ISSN | 0386-300X |
NCID | AA00508441 |
Content Type | Journal Article |
language | English |
Copyright Holders | Copyright Ⓒ 2021 by Okayama University Medical School |
File Version | publisher |
Refereed | True |
PubMed ID | 34955534 |
Web of Science KeyUT | 000735297900002 |
NAID | 120007180286 |
FullText URL | fulltext.pdf |
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Author | Selvam, Karthik Paneer| Nagahata, Taichi| Kato, Kosuke| Koreishi, Mayuko| Nakamura, Toshiyuki| Nakamura, Yoshimasa| Nishikawa, Takeshi| Satoh, Ayano| Hayashi, Yasuhiko| |
Keywords | Carbon Nanohorns Cellulose Skin sensitization Composites Bio-compatible |
Published Date | 2021-10-23 |
Publication Title | Biomaterials Research |
Volume | volume24 |
Issue | issue1 |
Publisher | Springer Nature |
Start Page | 18 |
ISSN | 1226-4601 |
Content Type | Journal Article |
language | English |
OAI-PMH Set | 岡山大学 |
Copyright Holders | © The Author(s). 2020 |
File Version | publisher |
PubMed ID | 33110624 |
DOI | 10.1186/s40824-020-00194-3 |
Web of Science KeyUT | 000672709800001 |
Related Url | isVersionOf https://doi.org/10.1186/s40824-020-00194-3 |
FullText URL | fulltext.pdf |
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Author | Nakamura, Makoto| Meguri, Yusuke| Ikegawa, Shuntaro| Kondo, Takumi| Sumii, Yuichi| Fukumi, Takuya| Iwamoto, Miki| Sando, Yasuhisa| Sugiura, Hiroyuki| Asada, Noboru| Ennishi, Daisuke| Tomida, Shuta| Fukuda-Kawaguchi, Emi| Ishii, Yasuyuki| Maeda, Yoshinobu| Matsuoka, Ken-Ichi| |
Published Date | 2021-06-23 |
Publication Title | Scientific Reports |
Volume | volume11 |
Issue | issue1 |
Publisher | Nature Research |
Start Page | 13125 |
ISSN | 2045-2322 |
Content Type | Journal Article |
language | English |
OAI-PMH Set | 岡山大学 |
Copyright Holders | © The Author(s) 2021 |
File Version | publisher |
PubMed ID | 34162921 |
DOI | 10.1038/s41598-021-92526-z |
Web of Science KeyUT | 000669995600012 |
Related Url | isVersionOf https://doi.org/10.1038/s41598-021-92526-z |
FullText URL | K0006389_abstract_review.pdf K0006389_fulltext.pdf K0006389_summary.pdf |
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Author | Nakamura, Tomoya| |
Published Date | 2021-03-25 |
Content Type | Thesis or Dissertation |
Grant Number | 甲第6389号 |
Granted Date | 2021-03-25 |
Thesis Type | Doctor of Philosophy in Dental Science |
Grantor | 岡山大学 |
language | English |
Copyright Holders | © Nakamuraet al. |
JaLCDOI | 10.18926/AMO/61904 |
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FullText URL | 75_2_219.pdf |
Author | Sugiura, Hiroyuki| Nishimori, Hisakazu| Matsuoka, Hirofumi| Nakamura, Keiichiro| Fujii, Keiko| Fujii, Nobuharu | Matsuoka, Ken-ichi | Maeda, Yoshinobu| |
Abstract | Acute promyelocytic leukemia (APL) is a hematological emergency that requires urgent intervention because of the high incidence of early hemorrhagic death. When patients with APL experience a synchronous solid organ tumor, the tumor’s treatment must also be done properly. Differentiation-inducing therapy using arsenic trioxide (ATO) has less hematological toxicity compared to cytotoxic chemotherapy and might be preferable for untreated APL patients with a synchronous solid organ tumor. Here we describe the first successful case of untreated APL and synchronous endometrial cancer (in an adult Japanese woman) treated with ATO consolidation therapy and the subsequent surgery and chemotherapy for endometrial cancer. |
Keywords | acute promyelocytic leukemia endometrial cancer arsenic trioxide synchronous multiple primary malignant tumor chemotherapy |
Amo Type | Case Report |
Publication Title | Acta Medica Okayama |
Published Date | 2021-04 |
Volume | volume75 |
Issue | issue2 |
Publisher | Okayama University Medical School |
Start Page | 219 |
End Page | 224 |
ISSN | 0386-300X |
NCID | AA00508441 |
Content Type | Journal Article |
language | English |
Copyright Holders | CopyrightⒸ 2021 by Okayama University Medical School |
File Version | publisher |
Refereed | True |
PubMed ID | 33953429 |
NAID | 120007029883 |
Author | Kunihiro, Tak| Ota, Tsutomu| Yamanaka, Masahiro| Nakamura, Eizo| |
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Published Date | 2021-05-17 |
Content Type | Data or Dataset |
JaLCDOI | 10.18926/61900 |
FullText URL Alternative | https://dream.misasa.okayama-u.ac.jp/?q=20201021051740-459379| |
FullText URL | fulltext.pdf |
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Author | Asada, Saori| Nishii, Nobuhiro| Shinya, Takayoshi| Miyoshi, Akihito| Morimoto, Yoshimasa| Miyamoto, Masakazu| Nakagawa, Koji| Nakamura, Kazufumi| Morita, Hiroshi| Ito, Hiroshi| |
Published Date | 2021-03-04 |
Publication Title | PLoS One |
Volume | volume16 |
Issue | issue3 |
Publisher | Public Library of Science |
Start Page | e0245502 |
ISSN | 1932-6203 |
Content Type | Journal Article |
language | English |
OAI-PMH Set | 岡山大学 |
Copyright Holders | © 2021 Asada et al. |
File Version | publisher |
PubMed ID | 33661956 |
DOI | 10.1371/journal.pone.0245502 |
NAID | 120007019113 |
Web of Science KeyUT | 000626604100103 |
Related Url | isVersionOf https://doi.org/10.1371/journal.pone.0245502 |
FullText URL | fulltext20210629-2.pdf |
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Author | Nakayama, Rie| Takaya, Yoichi| Nakamura, Kazufumi| Kondo, Megumi| Kobayashi, Kaoru| Ohno, Yuko| Amioka, Naofumi| Akagi, Satoshi| Yoshida, Masashi| Miyoshi, Toru| Ito, Hiroshi| |
Keywords | Dispersion Elasticity Myocardium Right ventricular function Shear wave elastography |
Note | This is an Accepted Manuscript of an article published by Elsevier. © 2021 Japanese College of Cardiology. Published by Elsevier Ltd. This manuscript version is made available under the CC-BY-NC-ND 4.0 License. http://creativecommons.org/licenses/by-nc-nd/4.0/. This is the accepted manuscript version. The formal published version is available at [https://doi.org/10.1016/j.jjcc.2021.01.015] .| |
Published Date | 2021-02-07 |
Publication Title | Journal of Cardiology |
Volume | volume78 |
Issue | issue1 |
Publisher | Elsevier |
Start Page | 17 |
End Page | 23 |
ISSN | 0914-5087 |
Content Type | Journal Article |
language | English |
OAI-PMH Set | 岡山大学 |
Copyright Holders | © 2021 Japanese College of Cardiology. Published by Elsevier Ltd. All rights reserved. |
File Version | author |
PubMed ID | 33568315 |
DOI | 10.1016/j.jjcc.2021.01.015 |
Web of Science KeyUT | 000661421700003 |
Related Url | isVersionOf https://doi.org/10.1016/j.jjcc.2021.01.015 |
FullText URL | fulltext20210630-1.pdf |
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Author | Nakamura, Kazufumi| Akagi, Satoshi| Ejiri, Kentaro| Yoshida, Masashi| Miyoshi, Toru| Sakaguchi, Masakiyo| Amioka, Naofumi| Suastika, Luh Oliva Saraswati| Kondo, Megumi| Nakayama, Rie| Takaya, Yoichi| Higashimoto, Yuichiro| Fukami, Kei| Matsubara, Hiromi| Ito, Hiroshi| |
Keywords | pulmonary artery smooth muscle cells RAGE aptamer |
Note | This is an Accepted Manuscript published by Elsevier. ©2021. This manuscript version is made available under the CC-BY-NC-ND 4.0 license http://creativecommons.org/licenses/by-nc-nd/4.0/| |
Published Date | 2020-12-30 |
Publication Title | Journal of Cardiology |
Volume | volume78 |
Issue | issue1 |
Publisher | Elsevier |
Start Page | 12 |
End Page | 16 |
ISSN | 09145087 |
NCID | AN10070473 |
Content Type | Journal Article |
language | English |
OAI-PMH Set | 岡山大学 |
Copyright Holders | © 2020 Japanese College of Cardiology. Published by Elsevier Ltd. All rights reserved. |
File Version | author |
PubMed ID | 33386219 |
DOI | 10.1016/j.jjcc.2020.12.009 |
Web of Science KeyUT | 000661421700002 |
Related Url | isVersionOf https://doi.org/10.1016/j.jjcc.2020.12.009 |
FullText URL | fulltext.pdf |
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Author | Nakayama, Rie| Takaya, Yoichi| Nakamura, Kazufumi| Toh, Norihisa| Ito, Hiroshi| |
Keywords | Shear wave elastography Elasticity Dispersion slope Liver dysfunction Heart failure |
Published Date | 2021-03-24 |
Publication Title | ESC Heart Failure |
Volume | volume8 |
Issue | issue3 |
Publisher | Wiley |
Start Page | 1751 |
End Page | 1758 |
ISSN | 2055-5822 |
Content Type | Journal Article |
language | English |
OAI-PMH Set | 岡山大学 |
Copyright Holders | © 2021 The Authors |
File Version | publisher |
PubMed ID | 33760377 |
DOI | 10.1002/ehf2.13318 |
NAID | 120007004154 |
Web of Science KeyUT | 000631949700001 |
Related Url | isVersionOf https://doi.org/10.1002/ehf2.13318 |
JaLCDOI | 10.18926/CTED/61578 |
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Title Alternative | Development of Lessons Based on Multiple Intelligences(MI)Theory |
FullText URL | cted_011_247_261.pdf |
Author | NAKAMURA, Saho| IMAI, Yasuyoshi| SAKO, Haruko| |
Abstract | Society5.0 の到来を迎え,個別最適化された学びや教科横断型学習の拡充等,教育改革が推進されている。これらの教育を実現させ得る理論的なアプローチとして,本稿では,人間の知能を言語,論理数学,音楽,身体運動,空間,対人,内省,博物的という8つの多面的な視点から捉える H.ガードナーの MI 理論(多重知能理論)に着目した。MI 理論に基づく音楽と体育の授業開発を試みた結果,子どもたちは自分の知能の特性を生かし,他者と協働して楽しみながら問題解決をする姿が見て取れた。また,ゴフマンのフレーム理論を援用し考察したところ,授業実践の鍵となったのは,授業の核に〈イメージ〉を設定することであった。以上より,MI 理論に基づく授業実践は激変する教育システムの支柱になり得る可能性が示唆された。 |
Keywords | MI 理論 (Multiple Intelligences Theory) イメージ (Imagination) |
Publication Title | Bulletin of Center for Teacher Education and Development, Okayama University |
Published Date | 2021-03-22 |
Volume | volume11 |
Start Page | 247 |
End Page | 261 |
ISSN | 2186-1323 |
language | Japanese |
Copyright Holders | Copyright © 2021 岡山大学教師教育開発センター |
File Version | publisher |
FullText URL | fulltext.pdf |
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Author | Akagi, Satoshi| Ejiri, Kentaro| Kasahara, Shingo| Nakamura, Kazufumi| Ito, Hiroshi| |
Keywords | vital capacity pulmonary artery pressure lung perfusion and oxygenation |
Published Date | 2019-02-15 |
Publication Title | Pulmonary Circulation |
Volume | volume9 |
Issue | issue1 |
Publisher | SAGE Publications |
Start Page | 2045894019831217 |
ISSN | 2045-8932 |
Content Type | Journal Article |
language | English |
OAI-PMH Set | 岡山大学 |
Copyright Holders | © The Author(s). 2019 |
File Version | publisher |
PubMed ID | 30698485 |
DOI | 10.1177/2045894019831217 |
Web of Science KeyUT | 000458818800001 |
Related Url | isVesionOf https://doi.org/10.1177/2045894019831217 |
JaLCDOI | 10.18926/ATM/61436 |
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FullText URL | 75_1_63.pdf |
Author | Tada, Katsuhiko| Miyagi, Yasunari| Nakamura, Kazue| Yorozu, Moe| Fukushima, Emi| Kumazawa, Kazumasa| Nakamura, Makoto| Kageyama, Misao| |
Abstract | We used a differential equation to identify the biological relationship between the maternal prepregnancy body mass index (BMI) and lactation on postpartum day 4 in Japanese women with neonatal separation. This retro-spective observational study included 252 mothers (135 primiparas, 117 multiparas) whose singleton neonates were admitted to a neonatal ICU. We formulated hypotheses based on breast anatomy to analyze the relation-ship between the expressed milk obtained on postpartum day 4 and the maternal prepregnancy BMI with the following differential equation: y’(x) = k y(x)/x, where k is the constant, x is the prepregnancy BMI, and y is the expressed milk volume. The formula was then obtained as y(x) = axk, where a is the constant. The Akaike information criterion (AIC) was used to estimate the regression equation with the maximum likelihood for primiparas and multiparas. The best criteria for BMI determined by the AIC were 20.89 kg/m2 in primiparas and 20.19 kg/m2 in multiparas. These were the optimal BMI values for lactation, coinciding with the median prepregnancy BMI in the study population (20.78 kg/m2 in primiparas and 20.06 kg/m2 in multiparas). The formula based on biomathematics might help establish the biological relationship between prepregnancy BMI and breastmilk volume. |
Keywords | biomathematics body mass index expressed milk lactation |
Amo Type | Original Article |
Publication Title | Acta Medica Okayama |
Published Date | 2021-02 |
Volume | volume75 |
Issue | issue1 |
Publisher | Okayama University Medical School |
Start Page | 63 |
End Page | 69 |
ISSN | 0386-300X |
NCID | AA00508441 |
Content Type | Journal Article |
language | English |
Copyright Holders | CopyrightⒸ 2021 by Okayama University Medical School |
File Version | publisher |
Refereed | True |
PubMed ID | 33649615 |
JaLCDOI | 10.18926/AMO/61433 |
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FullText URL | 75_1_45.pdf |
Author | Otsuka, Hiroaki| Miyoshi, Toru| Ejiri, Kentaro| Kohno, Kunihisa| Nakahama, Makoto| Doi, Masayuki| Munemasa, Mitsuru| Murakami, Masaaki| Nakamura, Kazufumi| Ito, Hiroshi| |
Abstract | Remote ischemic preconditioning (RIPC) is a promising strategy for protecting against ischemic reperfusion injury. This study is a secondary analysis of a randomized study that aimed to evaluate the effect of RIPC on the early increase in serum creatinine (SCr) following percutaneous coronary intervention (PCI), which is associ-ated with contrast-induced acute kidney injury. Patients with stable angina undergoing elective PCI were assigned to control, RIPC, and continuous infusion of nicorandil (nicorandil) groups. The endpoint of this study was the incidence of the early increase in SCr, a predictor of contrast-induced acute kidney injury, which was defined as either a > 20% or absolute increase by 0.3 mg/dl of SCr levels after 24 h of PCI. This study included 220 patients for whom a dataset of SCr values was available. The incidence of the early increase in SCr was significantly lower in the RIPC than in the control (1.3% vs 10.8%, p = 0.03) group, but was not significantly different between the nicorandil and control groups. In multivariate analysis, RIPC remained a significant fac-tor associated with a reduction in the incidence of early increase in SCr. RIPC reduces the incidence of early increase in SCr in patients with stable angina following elective PCI. |
Keywords | remote ischemic preconditioning stable angina serum creatinine acute kidney injury |
Amo Type | Original Article |
Publication Title | Acta Medica Okayama |
Published Date | 2021-02 |
Volume | volume75 |
Issue | issue1 |
Publisher | Okayama University Medical School |
Start Page | 45 |
End Page | 53 |
ISSN | 0386-300X |
NCID | AA00508441 |
Content Type | Journal Article |
language | English |
Copyright Holders | CopyrightⒸ 2021 by Okayama University Medical School |
File Version | publisher |
Refereed | True |
PubMed ID | 33649613 |
FullText URL | fulltext.pdf |
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Author | Ichikawa, Keishi| Miyoshi, Toru| Osawa, Kazuhiro| Miki, Takashi| Toda, Hironobu| Ejiri, Kentaro| Yoshida, Masatoki| Nanba, Yusuke| Yoshida, Masashi| Nakamura, Kazufumi| Morita, Hiroshi| Ito, Hiroshi| |
Keywords | Cardiovascular disease Computed tomography Coronary artery calcium Non-alcoholic fatty liver disease Risk stratification |
Published Date | 2021-01-07 |
Publication Title | Cardiovascular Diabetology |
Volume | volume20 |
Issue | issue1 |
Publisher | BMC |
Start Page | 2021 |
ISSN | 1475-2840 |
NCID | AA12050431 |
Content Type | Journal Article |
language | English |
OAI-PMH Set | 岡山大学 |
Copyright Holders | © The Author(s) 2021. |
File Version | publisher |
PubMed ID | 33413363 |
DOI | 10.1186/s12933-020-01192-4 |
Web of Science KeyUT | 000608278200003 |
Related Url | isVersionOf https://doi.org/10.1186/s12933-020-01192-4 |
FullText URL | fulltext.pdf |
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Author | Sato, Hiroki| Nakamura, Takao| Kusuhara, Toshimasa| Kenichi, Kobara| Kuniyasu, Katsushi| Kawashima, Takaki| Hanayama, Kozo| |
Keywords | Phase angle Bioelectrical impedance analysis Cole–Cole model Muscle quality |
Published Date | 2020-10-31 |
Publication Title | Journal of Physiological Sciences |
Volume | volume70 |
Issue | issue1 |
Publisher | Springer |
Start Page | 53 |
ISSN | 1880-6546 |
NCID | AA12129145 |
Content Type | Journal Article |
language | English |
OAI-PMH Set | 岡山大学 |
Copyright Holders | © Authors |
File Version | publisher |
PubMed ID | 33129254 |
DOI | 10.1186/s12576-020-00780-z |
Web of Science KeyUT | 000587996200002 |
Related Url | isVersionOf https://doi.org/10.1186/s12576-020-00780-z |
FullText URL | fulltext.pdf |
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Author | Potiszil, Christian| Tanaka, Ryoji| Kobayashi, Katsura| Kunihiro, Tak| Nakamura, Eizo| |
Keywords | Hayabusa2 Ryugu Sample return Organic matter Albedo. Astrobiology 20, 916–921 |
Published Date | 2020-07-08 |
Publication Title | Astrobiology |
Volume | volume20 |
Issue | issue7 |
Publisher | Mary Ann Liebert |
Start Page | 916 |
End Page | 921 |
ISSN | 1531-1074 |
NCID | AA11837332 |
Content Type | Journal Article |
language | English |
Copyright Holders | © Christian Potiszil et al., 2020 |
File Version | publisher |
PubMed ID | 32543220 |
DOI | 10.1089/ast.2019.2198 |
Web of Science KeyUT | 000541711900001 |
Related Url | isVersionOf https://doi.org/10.1089/ast.2019.2198 |