result 1530 件
| JaLCDOI | 10.18926/21104 |
|---|---|
| Title Alternative | Effects of serial bathing on fatty acid composition of adrenal and serum cholesterol ester in rats |
| FullText URL | pitsr_054_019_024.pdf |
| Author | Seno, Toshinobu| Harada, Hideo| Mifune, Masaaki| Morinaga, Hiroshi| |
| Abstract | The effects of serial bathing (10 minutes bathing in a city water or hot spring in Misasa, 40℃, once daily for 1-4 weeks) on fatty acid composition of cholesterol ester of the adrenal glands and serum was studied in both normal and hypercholesteremic rats. Although the adrenal cholesterol ester levels were relatively unaffected in rats treated with serial bathing as well as non-treated rats, the proportion of 18 : 2 was increased in rats treated with hot spring bathing for 3-4 weeks. The serum cholesterol ester levels in both normal and hypercholesteremic rats tended to decrease after serial bathing for 3-4 weeks compared with non-treated rats. The fatty acid composition of serum cholesterol ester in normal rats was unaffected. The composition in hypercholesteremic rats showed an increase in the proportion of 16 : 1 and 18 : 1 and a decrease of 18 : 2 and 20: 4 compared with normal rats. When those of hypercholesteremic rats were treated with serial bathing for 3 weeks, particularly with hot spring bathing, the proportion of 16 : 1, 18: 2 and 20 : 4 showed a tendency to approach that in tormal rats. The findings indicate that serial hot spring bathing for 3-4 weeks, unlike city water bathing, exerts an influence on the fatty acid composition of cholesterol ester of the rat adrenal glands and it also improves the fatty acid compsition of serum cholesterolester of hypercholesteremic rats. |
| Publication Title | 岡山大学温泉研究所報告 |
| Published Date | 1984-03-25 |
| Volume | volume54 |
| Start Page | 19 |
| End Page | 24 |
| ISSN | 0369-7142 |
| language | Japanese |
| File Version | publisher |
| NAID | 120002310999 |
| JaLCDOI | 10.18926/21103 |
|---|---|
| Title Alternative | Effects of swimming training in the hot spring pool on ventilatory function in bronchial asthma |
| FullText URL | pitsr_054_013_018.pdf |
| Author | Sudo, Michiyasu| Komagoe, Haruki| Okada, Chiharu| Nakago, Jitsuo| Tanizaki, Yoshiro| Morinaga, Hiroshi| |
| Abstract | Effect of free swimming training in the hot spring pool (30℃) on ventilatory function were observed in nine patients with intractable asthma by measuring FVC, FEV(1.0), PEFR, MMF, V(50), V(25). 1. Swimming in the hot spring pool for three months allowed the reduction of glucocorticoid used for their asthma attack. 2. Although FVC was not affected by swimming training, EEV(1.0), PEFR, MMF, V(50), V(25) which represent obstructive ventilatory function were gradually improved by swimming training. The results show that free swimming training in the hot springpool is clinically available in intractable asthma. |
| Publication Title | 岡山大学温泉研究所報告 |
| Published Date | 1984-03-25 |
| Volume | volume54 |
| Start Page | 13 |
| End Page | 18 |
| ISSN | 0369-7142 |
| language | Japanese |
| File Version | publisher |
| NAID | 120002310964 |
| Author | Inoue, Taeko| Tanizaki, Yoshiro| Morinaga, Hiroshi| |
|---|---|
| Published Date | 1984-11-30 |
| Publication Title | 岡山大学温泉研究所報告 |
| Volume | volume55 |
| Content Type | Data or Dataset |
| JaLCDOI | 10.18926/21095 |
|---|---|
| Title Alternative | Spa therapy for patients with chronic obstructive lung disease |
| FullText URL | pitsr_055_007_010.pdf |
| Author | Tanizaki, Yoshiro| Komagoe, Haruki| Sudo, Michiyasu| Morinaga, Hiroshi| Kitani, Hikaru| Nakagawa, Saburo| Kimura, Ikuro| |
| Abstract | Histamine releasse from basophils induced by house dust and C. albicans was examined in 30 patients with bronchial asthma. House dust and C. albicans caused a significant amount of histamine release in subjects with a RAST score to corresponding allergen. A close correlation was found between house dust- and anti-IgE-induced histamine release. However, histamine release induced by C. albicans was considerably different from the release induced by anti-IgE. |
| Publication Title | 岡山大学温泉研究所報告 |
| Published Date | 1984-11-30 |
| Volume | volume55 |
| Start Page | 7 |
| End Page | 10 |
| ISSN | 0369-7142 |
| language | English |
| File Version | publisher |
| NAID | 120002310939 |
| JaLCDOI | 10.18926/21094 |
|---|---|
| Title Alternative | Spa therapy for patients with chronic obstructive lung disease |
| FullText URL | pitsr_055_001_006.pdf |
| Author | Tanizaki, Yoshiro| Komagoe, Haruki| Sudo, Michiyasu| Nakago, Jitsuo| Morinaga, Hiroshi| Ohtani, Jun| Kimura, Ikuro| |
| Abstract | Thirty-six patients with chronic obstructive lung disease (34 cases with bronchial asthma, one case with chronic bronchiolitis and one case with pulmonary emphysema) have received spa therapy. Clinical effects of sa therapy on patients with bronchial asthma depended on patient age and asthma types classified by allergic reactions and clinical symptoms. Spa therapy was effective in the cases with ages more than 31 years and the cases with non-atopic type of bronchial asthma. Regarding asthma type classified by clinical symptoms, spa therapy was more effective in the cases with bronchiolar obstructive type and the cases with bronchospasm + hypersecretion type than in the cases with bronchospasm type of bronchial asthma. |
| Publication Title | 岡山大学温泉研究所報告 |
| Published Date | 1984-11-30 |
| Volume | volume55 |
| Start Page | 1 |
| End Page | 6 |
| ISSN | 0369-7142 |
| language | Japanese |
| File Version | publisher |
| NAID | 120002311032 |
| JaLCDOI | 10.18926/21086 |
|---|---|
| Title Alternative | Effect of serial bathing on circadian variation of plasma metabolites in rats |
| FullText URL | pitsr_056_035_043.pdf |
| Author | Seno, Toshinobu| Harada, Hideo| Mifune, Masaaki| Morinaga, Hiroshi| |
| Abstract | The effect of serial bathing (10-minute bathing in city water or Misasa hot spring, 40℃, once daily for one or four weeks) on the circadian variations of plasma metabolites was studied in three groups of rats : hot spring bathing rats, city water bathing rats and non-treated rats. Plasma obtained by decapitation at 8:00, 12:00, 16:00, 20:00 and 24:00 hours was analysed for catecholamines (CA), free fatty acids (FFA), cholesterol (C) and glucose. 1) Noradrenaline (NA) and adrenaline (A) were significantly lower at 24:00 hours with significantly lower 24-hour average concentrations and also with significantly different diurnal patterns in the 1-week hot spring bathing rats; in the 4-week hot spring bathing rats, lower 24-hour average concentrarion of A was the only significant finding. The results suggest the suppressive effect of hot spring bathing on the sympathetic system or pituitary gland-adrenal medulla; they also suggest the adaptation to hot spring bathing. 2) Free fatty acids were significantly higher in the 1-week hot spring bathing rats at 12:00 hours as compared with non-treated rats and city water bathing rats. The 4-week hot spring bathing rats showed concentration of FFA not different from the remaining two groups of rats. No significant difference was noted in diurnal patterns among the three groups of rats. The results suggest that the high FFA concentrations in the 1-week hot spring bathing rats are related to the physico-chemical constituents of the hot spring to some extent and that the rats adapt themselves to bathing during the 4-week preriod. 3) Cholesterol was significantly lower in the 4-week hot spring bathing rats as compared with non-treated rats and city water bathing rats; no different diurnal patterns were noted among the three groups of rats. The results suggest the suppressive effect of 4-week hot spring bathing on plasma cholesterol concentrations as reported previously by us. 4) No Significant difference was noted in concentrations as well as in diurnal patterns of plasma glucose among the three groups of rats. The results suggest that bathing has no significan effect on concentrations and diurnal patterns of plasma glucose in healthy rats. |
| Publication Title | 岡山大学温泉研究所報告 |
| Published Date | 1985-03-30 |
| Volume | volume56 |
| Start Page | 35 |
| End Page | 43 |
| ISSN | 0369-7142 |
| language | Japanese |
| File Version | publisher |
| NAID | 120002310969 |
| JaLCDOI | 10.18926/21085 |
|---|---|
| Title Alternative | Automatic measurement of oxygen isotope ratio of water samples |
| FullText URL | pitsr_056_027_034.pdf |
| Author | Chiba, Hitoshi| Sakai, Hitoshi| Yasutake, Masatoshi| |
| Abstract | The automatic sample preparation system for oxygen isotope analysis of natural water samples was constructed. The system is essentially a modification of that originally designed by W. Dansgaard in the University of Copenhagen. Sixty water samples of 5 ml each are automatically equilibrated with CO(2) of 30 ml NTP each within 4.5 hours. The equilibrated CO(2) gases are successively measured for their oxygen isotopic ratios by an automatic mas-sspectrometer, VG903. The time required for the measurement of the 60 CO(2) samples is about 15 hours; thus approximately 20 hours are required to complete the isotopic measurements of 60 water samples. The accuracy of the oxygen isotopic analyses is about 0.1%. The result of oxygen isotopic analyses by the automatic preparation system agrees with that of the conventional method within about +0.1%. The results indicate that the automatic preparation system is applicable for the oxygen isotope analysis of natural water samples. |
| Publication Title | 岡山大学温泉研究所報告 |
| Published Date | 1985-03-30 |
| Volume | volume56 |
| Start Page | 27 |
| End Page | 34 |
| ISSN | 0369-7142 |
| language | Japanese |
| File Version | publisher |
| NAID | 120002310952 |
| JaLCDOI | 10.18926/21084 |
|---|---|
| Title Alternative | Spa therapy for patients with chronic obstructive lung disease |
| FullText URL | pitsr_056_023_026.pdf |
| Author | Sudo, Michiyasu| Komagoe, Haruki| Tanizaki, Yoshiro| Morinaga, Hiroshi| |
| Abstract | During last three years, 41 patients with chronic obstructive lung disease (39 cases with bronchial asthma and 2 cases with chronic bronchiolitis) received spa therapy at Department of Medicine, Okayama University Medical School, Misasa Medical Branch. 1. Twenty three (56%) out of 41 cases came from Okayama prefecture and 10 cases (24.4%) from Tottori prefecture for spa therapy. In twenty five (61.0%) out of 41 cases, their ages were over 50 years. 2. Thirty nine patients with bronchial asthma were divided into three asthma types classified by clinical symptoms : Ia ; 16 cases (41.0%), Ib; 13 cases (33.3%) and II ; 10 cases (25.7%). Pulmonary function tests for these patients showed that small airways obstruction was most remarkable in type II asthma. 3. The mean serum IgE level of all asthmatic patients (39 cases) was 653.9U/ml. In skin test by allergens, positive immediate skin reaction was shown in 18 cases (46.2%) by Candida and 12 cases (30.8%) by house dust. Specific IgE anti-bodies were found in 9 cases (23.1%) for house dust and 3 cases (7.7%) for Candida. |
| Publication Title | 岡山大学温泉研究所報告 |
| Published Date | 1985-03-30 |
| Volume | volume56 |
| Start Page | 23 |
| End Page | 26 |
| ISSN | 0369-7142 |
| language | Japanese |
| File Version | publisher |
| NAID | 120002311025 |
| JaLCDOI | 10.18926/21083 |
|---|---|
| Title Alternative | 好塩基球からのヒスタミン遊離に関する研究. 5.臨床的評価 |
| FullText URL | pitsr_056_017_021.pdf |
| Author | Tanizaki, Yoshiro| Komagoe, Haruki| Sudo, Michiyasu| Morinaga, Hiroshi| |
| Abstract | 過去3年間にわたり,気管支喘息患者末梢血好塩基球からのヒスタミン遊離について,ヒスタミン自動分析装置を用いて全血法により検討を加えてきた. 1. 抗ヒトIgE によるヒスタミン遊離は,症例間で著しい差がみられた. この際血清IgE値が高値を示す症例では全般的に高度なヒスタシソ遊離がみられたが,血清IgE値が正常かまたはむしろ低値を示す症例のヒスタミン遊離は,かなり高度なものから全くみられないものまでさまざまであった. 2.ハウスダストやカンジダなどの抗原物質によるヒスタミン遊離は,特異的IgE抗体依存性であり,抗体価が上昇するにつれヒスタミン遊離は高度となる傾向がみられた. しかし,ハウスダストとカンジダによるヒスタミン遊離には若干の差がみられた. すなわち,ハウスダストと抗ヒトIgE によるヒスタミン遊離の間には密接な関連がみられたが,カンジダと抗ヒトIgEの間には全く関連がみられなかった. またカンジダによるヒスタミン遊離においては,IgE系反応以外の反応が関与する可能性が一部示唆された. |
| Publication Title | 岡山大学温泉研究所報告 |
| Published Date | 1985-03-30 |
| Volume | volume56 |
| Start Page | 17 |
| End Page | 21 |
| ISSN | 0369-7142 |
| language | English |
| File Version | publisher |
| NAID | 120002310985 |
| JaLCDOI | 10.18926/21079 |
|---|---|
| Title Alternative | Radioactivity and chromosome aberrations of residents of Misasa Spa |
| FullText URL | pitsr_056_001_004.pdf |
| Author | Morinaga, Hiroshi| Mifune, Masaaki| Furuno, Katsuaki| |
| Abstract | Misasa Spa is one of the most highly radioactive hot springs in Japan, the waters of which contain mainly (222)Rn (437±132 Bq/liter). Radon contents of indoor air of private houses and health resort hotels (built of wood) at Misasa Spa range from 18.5 to 55.5 mBq/liter and 22.2 to 129.5 mBq/liter, respectively. Radon contents in the air of facilities using spring waters at Misasa Branch Hospital of Okayama University were measured to be ; bathroom 807±78 mBq/liter; Hubbardtank bathroom 5306±2568 mBq/liter ; the drinking hall 1491±178 mBq/liter. The environmental and dose rate inside private houses has been measured to be 14.0±1.8 μR/h. Chromosome aberrations (dicentrics) in the peripheral blood lymphocytes of residents of Misasa Spa were investigated in 14 persons; the mean value of aberration frequencies were 0.21%. |
| Publication Title | 岡山大学温泉研究所報告 |
| Published Date | 1985-03-30 |
| Volume | volume56 |
| Start Page | 1 |
| End Page | 4 |
| ISSN | 0369-7142 |
| language | Japanese |
| File Version | publisher |
| NAID | 120002311024 |
| Author | Nago, Hiroshi| |
|---|---|
| Published Date | 1983-12-01 |
| Publication Title | 岡山大学環境管理センター報 |
| Volume | volume5 |
| Content Type | Others |
| Author | Tsukube, Hiroshi| |
|---|---|
| Published Date | 1984-11-01 |
| Publication Title | 岡山大学環境管理センター報 |
| Volume | volume6 |
| Content Type | Others |
| Author | Tsukube, Hiroshi| |
|---|---|
| Published Date | 1987-11-01 |
| Publication Title | 岡山大学環境管理センター報 |
| Volume | volume9 |
| Content Type | Others |
| Author | Nagai, Hiroshi| |
|---|---|
| Published Date | 1983-04 |
| Publication Title | 岡山実験動物研究会報 |
| Volume | volume1 |
| Content Type | Others |
| Author | Nagai, Hiroshi| |
|---|---|
| Published Date | 1984-04 |
| Publication Title | 岡山実験動物研究会報 |
| Volume | volume2 |
| Content Type | Others |
| Author | Suzuki, Kazunori| Nagai, Hiroshi| |
|---|---|
| Published Date | 1984-04 |
| Publication Title | 岡山実験動物研究会報 |
| Volume | volume2 |
| Content Type | Journal Article |
| Author | Nagai, Hiroshi| |
|---|---|
| Published Date | 1984-04 |
| Publication Title | 岡山実験動物研究会報 |
| Volume | volume2 |
| Content Type | Others |
| Author | Nagai, Hiroshi| |
|---|---|
| Published Date | 1985-04 |
| Publication Title | 岡山実験動物研究会報 |
| Volume | volume3 |
| Content Type | Others |
| Author | Takahashi, Shinji| Ichinose, Takamichi| Sagai, Masaru| Takahashi, Hiroshi| |
|---|---|
| Published Date | 1992-06 |
| Publication Title | 岡山実験動物研究会報 |
| Volume | volume9 |
| Content Type | Journal Article |
| Author | Ohara, Hiroshi| |
|---|---|
| Published Date | 1993-06 |
| Publication Title | 岡山実験動物研究会報 |
| Volume | volume10 |
| Content Type | Others |
