| ID | 56254 |
| JaLCDOI | |
| FullText URL | |
| Author |
Sato, Daisuke
Department of Nephrology, Juntendo University Faculty of Medicine
Gohda, Tomohito
Department of Nephrology, Juntendo University Faculty of Medicine
Kihara, Masao
Department of Nephrology, Juntendo University Faculty of Medicine
Kanaguchi, Yasuhiko
Department of Nephrology, Juntendo University Faculty of Medicine
Kobayashi, Takashi
Department of Nephrology, Juntendo University Faculty of Medicine
Mano, Satoshi
Department of Nephrology, Juntendo University Faculty of Medicine
Sasaki, Yu
Department of Nephrology, Juntendo University Faculty of Medicine
Nohara, Nao
Department of Nephrology, Juntendo University Faculty of Medicine
Murakoshi, Maki
Department of Nephrology, Juntendo University Faculty of Medicine
Nakata, Junichiro
Department of Nephrology, Juntendo University Faculty of Medicine
Suzuki, Hitoshi
Department of Nephrology, Juntendo University Faculty of Medicine
Ueda, Seiji
Department of Nephrology, Juntendo University Faculty of Medicine
Horikoshi, Satoshi
Department of Nephrology, Juntendo University Faculty of Medicine
Suzuki, Yusuke
Department of Nephrology, Juntendo University Faculty of Medicine
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| Abstract | Some patients with chronic kidney disease (CKD) receiving hemodialysis develop erythropoietin-resistant anemia, possibly due to zinc deficiency. The frequency of zinc deficiency in CKD (stages 1-5 and 5D) and CKD improvement via zinc supplementation are not completely verified. Here 500 CKD patients (Stage 1/2, n=100; Stage 3, n=100; Stage 4, n=100, Stage n=5, 100; Stage 5D, n=100) will be recruited to determine the frequency of serum zinc deficiency at each CKD stage. Patients with serum zinc concentrations <80 μg/dL will be treated with zinc acetate dihydrate (NobelzinR) to evaluate its effects on hypozincemia, taste disturbances, and anemia.
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| Keywords | zinc acetate dihydrate
anemia
chronic kidney disease
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| Amo Type | Clinical Study Protocol
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| Publication Title |
Acta Medica Okayama
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| Published Date | 2018-10
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| Volume | volume72
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| Issue | issue5
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| Publisher | Okayama University Medical School
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| Start Page | 535
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| End Page | 538
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| ISSN | 0386-300X
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| NCID | AA00508441
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| Content Type |
Journal Article
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| language |
English
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| Copyright Holders | CopyrightⒸ 2018 by Okayama University Medical School
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| File Version | publisher
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| Refereed |
True
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| PubMed ID |