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JaLCDOI 10.18926/AMO/56865
FullText URL 73_3_229.pdf
Author Hamasaki, Ichiro| Shibata, Kiyo| Shimizu, Takehiro| Kono, Reika| Morizane, Yuki| Shiraga, Fumio|
Abstract During strabismus surgery using illumination from a light source, patients complain of photophobia. The NGENUITYⓇ (Alcon) system is equipped with a high-dynamic-range (HDR) camera. A 4K display viewed by wearing circularly polarized glasses provides clear three-dimensional images of the operative field. A light source is usually required for surgeries of the anterior segment (including strabismic surgery), but the digital processing function of the NGENUITYⓇ system allows image display in relatively dark regions even without a light source. We devised a novel ‘lights-out’ surgery that does not use a microscope’s light source, and we examined the usefulness of this technique in 2 cases of strabismic surgery. We performed strabismus surgery using the NGENUITYⓇ system in two patients between January and June 2018. The HDR function was used, and the aperture was opened to the maximum while the gain was adjusted. Surgery was conducted without using the microscope’s light source. We report the 2 cases’ results and evaluate the novel method. The surgeries were performed without problem even though the microscope’s light source was not used. The patients’ photophobia was alleviated. Lights-out surgery is a potentially useful modality for strabismus surgery.
Keywords head-up surgery 3D vision system high dynamic range video enhancement strabismus surgery
Amo Type Original Article
Publication Title Acta Medica Okayama
Published Date 2019-06
Volume volume73
Issue issue3
Publisher Okayama University Medical School
Start Page 229
End Page 233
ISSN 0386-300X
NCID AA00508441
Content Type Journal Article
language English
Copyright Holders CopyrightⒸ 2019 by Okayama University Medical School
File Version publisher
Refereed True
PubMed ID 31235970
JaLCDOI 10.18926/AMO/56864
FullText URL 73_3_223.pdf
Author Sugiu, Kazuhisa| Furumatsu, Takayuki| Kodama, Yuya| Kamatsuki, Yusuke| Okazaki, Yoshiki| Okazaki, Yuki| Hiranaka, Takaaki| Ozaki, Toshifumi|
Abstract Anterior cruciate ligament (ACL) reconstruction (ACLR) after ACL rupture improves the instability of the knee joint and decreases mechanical stress to the meniscus and articular cartilage. However, there are reports that post-traumatic osteoarthritis (PTOA) is observed over time following ACLR. In this study, we assessed changes in cartilage lesions by arthroscopic findings following anatomical double-bundle ACLR and at post-operative second-look arthroscopy about 14 months later. We retrospectively evaluated 37 knees in cases with patients <40 years of age who had undergone an anatomical double-bundle ACL reconstruction <1 year after ACL rupture injury from March 2012 to December 2016. Clinical results and arthroscopic cartilage/meniscal lesion were evaluated and compared between a cartilage lesion-detected group and intact-cartilage group. Surgery improved anteroposterior laxity and other clinical measures; however, cartilage lesions were detected at 11 sites during ACLR and at 54 sites at second-look arthroscopy. The periods from injury to second-look arthroscopy and from ACLR to second-look arthroscopy were significantly longer in the cartilage-lesion group (n=23) than in the intact-cartilage group (n=14). Conversely, 96% of meniscal damage observed during ACLR was cured at the time of second-look arthroscopy. Knee articular cartilage lesions after ACL rupture cannot be completely suppressed, even using the anatomical ACL reconstruction technique. This study suggested that articular cartilage lesions can progress to a level that can be confirmed arthroscopically at approximately 17 months after ACL injury. Therefore, in ACLR patients, the possibility of developing knee articular cartilage lesions and PTOA should be considered.
Keywords anterior cruciate ligament reconstruction post-traumatic osteoarthritis meniscal lesion cartilage lesions second-look arthroscopy
Amo Type Original Article
Publication Title Acta Medica Okayama
Published Date 2019-06
Volume volume73
Issue issue3
Publisher Okayama University Medical School
Start Page 223
End Page 228
ISSN 0386-300X
NCID AA00508441
Content Type Journal Article
language English
Copyright Holders CopyrightⒸ 2019 by Okayama University Medical School
File Version publisher
Refereed True
PubMed ID 31235969
JaLCDOI 10.18926/AMO/56863
FullText URL 73_3_213.pdf
Author Nishina, Saori| Matsuura, Koji| Naruse, Keiji|
Abstract We investigated the relationship between human sperm rheotaxis and motile sperm trajectories by using poly-(dimethylsiloxane) (PDMS)-based cylindrical microfluidic channels with inner diameters of 100 μm, 50 μm, and 70 μm, which corresponded to the inner diameter of the human isthmus, the length of a sperm and a diameter intermediate between the two, respectively. We counted the number of rheotaxic sperm and sperm with spiral motion. We also analyzed motile sperm trajectories. As the cylindrical channel diameter was decreased, the percentage of sperm cells exhibiting rheotaxis, the percentage of sperm cells exhibiting spiral motion, the frequency-to-diameter ratio of the sperm cells’ spiral trajectories, and the surface area of the microfluidic channel increased, while the flagellar motion at the channel wall decreased. The percentage of sperm exhibiting a spiral trajectory and the frequency-to-diameter ratio of the sperm cells’ spiral trajectories were thus affected by the channel diameter. Our findings suggest that the oviduct structure affects the swimming properties of sperm cells, guiding them from the uterus to the ampulla for egg fertilization. These results could contribute to the development of motile sperm-sorting microfluidic devices for assisted reproductive technologies.
Keywords sperm motility trajectory microfluidic channel rheotaxis oviduct structure
Amo Type Original Article
Publication Title Acta Medica Okayama
Published Date 2019-06
Volume volume73
Issue issue3
Publisher Okayama University Medical School
Start Page 213
End Page 221
ISSN 0386-300X
NCID AA00508441
Content Type Journal Article
language English
Copyright Holders CopyrightⒸ 2019 by Okayama University Medical School
File Version publisher
Refereed True
PubMed ID 31235968
JaLCDOI 10.18926/AMO/56862
FullText URL 73_3_205.pdf
Author Mukai, Yuko| Sakurai, Toru| Watanabe, Toshiyuki| Sako, Tomoko| Sugimoto, Morito| Kimata, Yoshihiro| Mori, Yoshiko| Nagasaka, Takeshi| Namba, Yuzaburo|
Abstract Intestinal vaginoplasty has several advantageous features, such as scarless surgery, low incidence of contraction of the reconstructed vagina, maintenance of vaginal depth, spontaneous mucus production, and a low rate of complications. Therefore, this technique is becoming popular in many countries. Following the global trend, the demand for intestinal vaginoplasty for transsexuals is also increasing in Japan. However, there are few reports on intestinal vaginoplasty in Japan. In this study, we examined the safety and effectiveness of rectosigmoid colon vaginoplasty in the Japanese population. We retrospectively surveyed 18 male-to-female transsexuals who underwent laparoscopic rectosigmoid colon vaginoplasty at the Okayama University Hospital Gender Center between October 2012 and December 2017. One patient had developed an anastomotic leak and 2 patients experienced vaginal prolapse, which needed revision surgery. Both adverse outcomes were comparable with those from previous studies. The anastomotic leak was managed adequately with conservative treatment. To avoid vaginal prolapse, it is important to decide the length of the rectosigmoid segment so that a pull on it does not cause it to become lax, while excessive stress on the feeder vessels is avoided. Based on our study, we concluded that rectosigmoid vaginoplasty was a reliable technique in the Japanese population.
Keywords vaginoplasty male-to-female transsexuals rectosigmoid colon
Amo Type Original Article
Publication Title Acta Medica Okayama
Published Date 2019-06
Volume volume73
Issue issue3
Publisher Okayama University Medical School
Start Page 205
End Page 211
ISSN 0386-300X
NCID AA00508441
Content Type Journal Article
language English
Copyright Holders CopyrightⒸ 2019 by Okayama University Medical School
File Version publisher
Refereed True
PubMed ID 31235967
JaLCDOI 10.18926/AMO/56861
FullText URL 73_3_197.pdf
Author Nishimura, Takeshi| Naito, Hiromichi| Matsuyama, Shigenari| Ishihara, Satoshi| Nakao, Atsunori| Nakayama, Shinichi|
Abstract Japan's population has been skewing toward the elderly, but the outcomes of advanced elderly trauma are not clear. Here we compared the outcomes of very elderly trauma patients (≧85 years old) with those of 65- to 84-year-old trauma patients. We retrospectively reviewed the medical records of patients treated at Hyogo Emergency Medical Center from August 2010 to August 2016; 631 patients were entered in the study. We divided them into the younger geriatrics (YG group, 65-84 years old: n=534) and older geriatrics (OG group, ≧85 years old: n=97). The group’s patient characteristics, mortality, 1-year survival rate, and Barthel index were tabulated and compared. The patients’ mean age was 75.6±7.5 years. There was no significant difference in mortality between the YG and OG groups (9.6% vs. 15.1%, odds ratio [OR] 1.73; 95% confidence interval [CI] 0.93-3.23, p=0.083). The 1-year survival rate (94.4% vs. 77.8%, OR 0.19, 95% CI 0.07-0.51; p<0.01) and Barthel index (Median score; 100 (IQR: 85-100) vs. 80 (IQR: 15-95), OR 0.98, 95% CI 0.97 to 0.99, p<0.01) differed significantly between the groups. Our study did not find a significant difference in-hospital mortality between patients in the YG group and those in the OG group.
Keywords aged injury mortality morbidity trauma
Amo Type Original Article
Publication Title Acta Medica Okayama
Published Date 2019-06
Volume volume73
Issue issue3
Publisher Okayama University Medical School
Start Page 197
End Page 203
ISSN 0386-300X
NCID AA00508441
Content Type Journal Article
language English
Copyright Holders CopyrightⒸ 2019 by Okayama University Medical School
File Version publisher
Refereed True
PubMed ID 31235966
JaLCDOI 10.18926/AMO/56860
FullText URL 73_3_189.pdf
Author Sakamoto, Shinji| Kawai, Hiroki| Okahisa, Yuko| Tsutsui, Ko| Kanbayashi, Takashi| Tanaka, Keiko| Mizuki, Yutaka| Takaki, Manabu| Yamada, Norihito|
Abstract Anti-N-methyl-D-aspartate receptor (NMDAR) encephalitis is a recently-discovered autoimmune disorder in which antibodies target NMDAR in the brain. The number of reported cases of anti-NMDAR encephalitis has increased rapidly. Anti-NMDAR encephalitis can be mistakenly diagnosed as psychiatric disorders because many patients present with prominent psychiatric symptoms and visit psychiatric institutions first. Thus, psychiatrists should cultivate a better understanding of anti-NMDAR encephalitis. In this review, we present the mechanisms, epidemiology, symptoms and clinical course, diagnostic tests, treatment and outcomes of patients with anti-NMDAR encephalitis. Furthermore, we discuss the diversity of clinical spectra of anti-NMDAR encephalitis, and demonstrate a differential diagnosis of psychiatric disease from the perspective of psychiatry.
Keywords NMDAR encephalitis psychiatric symptom schizophrenia mood disorder
Amo Type Review
Publication Title Acta Medica Okayama
Published Date 2019-06
Volume volume73
Issue issue3
Publisher Okayama University Medical School
Start Page 189
End Page 195
ISSN 0386-300X
NCID AA00508441
Content Type Journal Article
language English
Copyright Holders CopyrightⒸ 2019 by Okayama University Medical School
File Version publisher
Refereed True
PubMed ID 31235965
FullText URL Tissue_Eng_A_2018_0348.pdf
Author Sogawa, Chiharu| Eguchi, Takanori| Okusha, Yuka| Ono, Kisho| Ohyama, Kazumi| Iizuka, Motoharu| Kawasaki, Ryu| Hamada, Yusaku| Takigawa, Masaharu| Sogawa, Norio| Okamoto, Kuniaki| Kozaki , Ken-ichi|
Keywords 3D tumoroid reporter assay Wnt/β-catenin signaling cancer metastasis metalloproteinase syngeneic transplantation tumoroid (tumor organoid)
Note This is an Accepted Manuscript of an article published by Mary Ann Liebert|
Published Date 2019-02-08
Publication Title Tissue Engineering Part A.
Volume volume25
Issue issue19-20
Publisher Mary Ann Liebert
Start Page 1413
End Page 1425
ISSN 19373341
NCID AA12306003
Content Type Journal Article
language English
OAI-PMH Set 岡山大学
File Version author
PubMed ID 30734664
DOI 10.1089/ten.TEA.2018.0348
NAID 120006788780
Web of Science KeyUT 000489035900008
Related Url isVersionOf https://doi.org/10.1089/ten.TEA.2018.0348
FullText URL O0004502.abstract-review.pdf.pdf O0004502.summary.pdf.pdf
Author Hayashi, Masako|
Published Date 2019-03-25
Content Type Thesis or Dissertation
Grant Number 乙第4502号
Granted Date 2019-03-25
Thesis Type Doctor of Philosophy in Letters
Grantor 岡山大学
language Japanese
FullText URL O0004501_abstract_review.pdf O0004501_fulltext.pdf
Author Moriya, Takeo|
Published Date 2019-03-25
Content Type Thesis or Dissertation
Grant Number 乙第4501号
Granted Date 2019-03-25
Thesis Type Doctor of Philosophy in Agriculture
Grantor 岡山大学
language Japanese
FullText URL O0004500_abstract_review.pdf O0004500_fulltext.pdf
Author Kawasaki, Hidenori|
Published Date 2019-03-25
Content Type Thesis or Dissertation
Grant Number 乙第4500号
Granted Date 2019-03-25
Thesis Type Doctor of Philosophy
Grantor 岡山大学
language English
FullText URL O0004499_abstract_review.pdf O0004499_fulltext.pdf
Author ALAM Md Jahangir|
Published Date 2019-03-25
Content Type Thesis or Dissertation
Grant Number 乙第4499号
Granted Date 2019-03-25
Thesis Type Doctor of Philosophy in Engineering
Grantor 岡山大学
language English
FullText URL O0004498_abstract_review.pdf O0004498_fulltext.pdf
Author Ishida, Takayuki|
Published Date 2019-03-25
Content Type Thesis or Dissertation
Grant Number 乙第4498号
Granted Date 2019-03-25
Thesis Type Doctor of Philosophy in Pharmaceutical Sciences
Grantor 岡山大学
language Japanese
FullText URL O0004497_abstract_review.pdf O0004497_fulltext.pdf
Author Ida, Takahiro|
Published Date 2019-03-25
Content Type Thesis or Dissertation
Grant Number 乙第4497号
Granted Date 2019-03-25
Thesis Type Doctor of Philosophy in Pharmaceutical Sciences
Grantor 岡山大学
language Japanese
FullText URL O0004496_abstract_review.pdf O0004496_fulltext.pdf
Author Iwai, Yuma|
Published Date 2019-03-25
Content Type Thesis or Dissertation
Grant Number 乙第4496号
Granted Date 2019-03-25
Thesis Type Doctor of Philosophy in Pharmaceutical Sciences
Grantor 岡山大学
language Japanese
FullText URL K0006008.abstract-review.pdf.pdf K0006008.fulltext.pdf.pdf
Author TIN HTUT AUNG|
Published Date 2019-03-25
Content Type Thesis or Dissertation
Grant Number 甲第6008号
Granted Date 2019-03-25
Thesis Type Doctor of Philosophy in Letters
Grantor 岡山大学
language English
FullText URL K0006007.abstract-review.pdf.pdf K0006007.fulltext.pdf.pdf
Author 孫 瑛鞠|
Published Date 2019-03-25
Content Type Thesis or Dissertation
Grant Number 甲第6007号
Granted Date 2019-03-25
Thesis Type Doctor of Philosophy in Letters
Grantor 岡山大学
language Japanese
FullText URL K0006006.abstract-review.pdf.pdf K0006006.fulltext.pdf.pdf
Author KIRA, Esra|
Published Date 2019-03-25
Content Type Thesis or Dissertation
Grant Number 甲第6006号
Granted Date 2019-03-25
Thesis Type Doctor of Philosophy in Letters
Grantor 岡山大学
language Japanese
FullText URL K0006005.abstract-review.pdf.pdf K0006005.fulltext.pdf.pdf
Author KHIN MAR THET|
Published Date 2019-03-25
Content Type Thesis or Dissertation
Grant Number 甲第6005号
Granted Date 2019-03-25
Thesis Type Doctor of Philosophy in Economics
Grantor 岡山大学
language English
FullText URL K0006004.abstract-review.pdf.pdf K0006004.fulltext.pdf.pdf
Author 閻 琳|
Published Date 2019-03-25
Content Type Thesis or Dissertation
Grant Number 甲第6004号
Granted Date 2019-03-25
Thesis Type Doctor of Philosophy in Letters
Grantor 岡山大学
language Japanese
FullText URL K0006003.abstract-review.pdf.pdf K0006003.fulltext.pdf.pdf
Author 孟 令禕|
Published Date 2019-03-25
Content Type Thesis or Dissertation
Grant Number 甲第6003号
Granted Date 2019-03-25
Thesis Type Doctor of Philosophy in Letters
Grantor 岡山大学
language Japanese