start-ver=1.4 cd-journal=joma no-vol= cd-vols= no-issue= article-no= start-page= end-page= dt-received= dt-revised= dt-accepted= dt-pub-year=2024 dt-pub=20240925 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=ダリア‘熱唱’における低温誘導花色退色メカニズムの解明による高品質切り花生産のための非退色系統の選抜 kn-title=Selection of non-fading lines for high quality cut-flower production in Dahlia variabilis ′Nessho′ by elucidating mechanisms of low temperature induced flower color fading en-subtitle= kn-subtitle= en-abstract= kn-abstract= en-copyright= kn-copyright= en-aut-name=MUTHAMIA EDNA KIRUMBA en-aut-sei=MUTHAMIA EDNA KIRUMBA en-aut-mei= kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=1 ORCID= affil-num=1 en-affil=Graduate School of Environmental and Life Science, Okayama University kn-affil=岡山大学大学院環境生命科学研究科 END start-ver=1.4 cd-journal=joma no-vol= cd-vols= no-issue= article-no= start-page= end-page= dt-received= dt-revised= dt-accepted= dt-pub-year=2024 dt-pub=20240925 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=植物細胞における亜硫酸の毒性機構に関する研究－亜硫酸毒性への細胞質酸性化と細胞酸化の関与の評価 kn-title=A study on toxic mechanisms of SO2 in plant cells - Evaluation of the involvement of cytosolic acidification and cellular oxidation in SO2 toxicity en-subtitle= kn-subtitle= en-abstract= kn-abstract= en-copyright= kn-copyright= en-aut-name=MAHDI MOZHGANI en-aut-sei=MAHDI MOZHGANI en-aut-mei= kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=1 ORCID= affil-num=1 en-affil=Graduate School of Environmental and Life Science, Okayama University kn-affil=岡山大学大学院環境生命科学研究科 END start-ver=1.4 cd-journal=joma no-vol= cd-vols= no-issue= article-no= start-page= end-page= dt-received= dt-revised= dt-accepted= dt-pub-year=2024 dt-pub=20240325 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=光共生性無腸動物Praesagittifera naikaiensisの行動メカニズムに関する研究 kn-title=Studies on behavioral mechanisms in a photosymbiotic acoel flatworm, Praesagittifera naikaiensis en-subtitle= kn-subtitle= en-abstract= kn-abstract= en-copyright= kn-copyright= en-aut-name=SAKAGAMITosuke en-aut-sei=SAKAGAMI en-aut-mei=Tosuke kn-aut-name=坂上登亮 kn-aut-sei=坂上 kn-aut-mei=登亮 aut-affil-num=1 ORCID= affil-num=1 en-affil=Graduate School of Environmental and Life Science, Okayama University kn-affil=岡山大学大学院環境生命科学研究科 END start-ver=1.4 cd-journal=joma no-vol= cd-vols= no-issue= article-no= start-page= end-page= dt-received= dt-revised= dt-accepted= dt-pub-year=2005 dt-pub=20051231 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=Galectin-9は、細胞周期の制御によりdb/db糖尿病マウスの糸球体肥大を抑制する kn-title=Galectin-9 inhibits glomerular hypertrophy in db/db diabetic mice via cell-cycle-dependent mechanisms en-subtitle= kn-subtitle= en-abstract= kn-abstract= en-copyright= kn-copyright= en-aut-name=BabaMasako en-aut-sei=Baba en-aut-mei=Masako kn-aut-name=馬場雅子 kn-aut-sei=馬場 kn-aut-mei=雅子 aut-affil-num=1 ORCID= affil-num=1 en-affil= kn-affil=岡山大学 END start-ver=1.4 cd-journal=joma no-vol= cd-vols= no-issue= article-no= start-page= end-page= dt-received= dt-revised= dt-accepted= dt-pub-year=2023 dt-pub=20230324 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=西南日本中国地方の後期新生代火山岩のハフニウム・ホウ素・リチウム・マグネシウム同位体システマティクス：沈み込み帯で発生するスラブ由来の流体の特性と輸送メカニズムの解明 kn-title=Hf-B-Li-Mg isotope systematics of late Cenozoic volcanic rocks from the Chugoku district, Southwest Japan: Implications for the property and transport mechanism of slab-derived fluids in the subduction zone en-subtitle= kn-subtitle= en-abstract= kn-abstract= en-copyright= kn-copyright= en-aut-name=ZHANGWei en-aut-sei=ZHANG en-aut-mei=Wei kn-aut-name=张伟 kn-aut-sei=张 kn-aut-mei=伟 aut-affil-num=1 ORCID= affil-num=1 en-affil=Graduate School of Natural Science and Technology, Okayama university kn-affil=岡山大学大学院自然科学研究科 END start-ver=1.4 cd-journal=joma no-vol= cd-vols= no-issue= article-no= start-page= end-page= dt-received= dt-revised= dt-accepted= dt-pub-year=2023 dt-pub=20230324 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=長時間酸処理したチタン-6アルミニウム-4バナジウム合金の即時軟組織接着性と機械的性質 kn-title=Immediate soft-tissue adhesion and the mechanical properties of the Ti–6Al–4V alloy after long-term acid treatment en-subtitle= kn-subtitle= en-abstract= kn-abstract= en-copyright= kn-copyright= en-aut-name=WangYaming en-aut-sei=Wang en-aut-mei=Yaming kn-aut-name=王亜明 kn-aut-sei=王 kn-aut-mei=亜明 aut-affil-num=1 ORCID= affil-num=1 en-affil=Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama University kn-affil=岡山大学大学院医歯薬学総合研究科 END start-ver=1.4 cd-journal=joma no-vol= cd-vols= no-issue= article-no= start-page= end-page= dt-received= dt-revised= dt-accepted= dt-pub-year=2022 dt-pub=20220325 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=六倍体栽培ガキにおける性の揺らぎの分子機構 kn-title=Molecular mechanisms for plastic sex expression in hexaploid persimmon en-subtitle= kn-subtitle= en-abstract= kn-abstract= en-copyright= kn-copyright= en-aut-name=MasudaKanae en-aut-sei=Masuda en-aut-mei=Kanae kn-aut-name=増田佳苗 kn-aut-sei=増田 kn-aut-mei=佳苗 aut-affil-num=1 ORCID= affil-num=1 en-affil=Graduate School of Environmental and Life Science, Okayama University kn-affil=岡山大学大学院環境生命科学研究科 END start-ver=1.4 cd-journal=joma no-vol= cd-vols= no-issue= article-no= start-page= end-page= dt-received= dt-revised= dt-accepted= dt-pub-year=2022 dt-pub=20220325 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=シロイヌナズナにおけるリンゴ酸誘導気孔閉口のメカニズム kn-title=The mechanism of malate-induced stomatal closure in Arabidopsis thaliana en-subtitle= kn-subtitle= en-abstract= kn-abstract= en-copyright= kn-copyright= en-aut-name=MimataYoshiharu en-aut-sei=Mimata en-aut-mei=Yoshiharu kn-aut-name=三俣好令 kn-aut-sei=三俣 kn-aut-mei=好令 aut-affil-num=1 ORCID= affil-num=1 en-affil=Graduate School of Environmental and Life Science, Okayama University kn-affil=岡山大学大学院環境生命科学研究科 END start-ver=1.4 cd-journal=joma no-vol= cd-vols= no-issue= article-no= start-page= end-page= dt-received= dt-revised= dt-accepted= dt-pub-year=2022 dt-pub=20220325 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=対称性知覚神経機構の心理物理学的・VEP研究 kn-title=Neural Mechanism of Visual Symmetry Perception: Psychophysical and Visual Evoked Potentials Study en-subtitle= kn-subtitle= en-abstract= kn-abstract= en-copyright= kn-copyright= en-aut-name=WANGMeng en-aut-sei=WANG en-aut-mei=Meng kn-aut-name=王萌 kn-aut-sei=王 kn-aut-mei=萌 aut-affil-num=1 ORCID= affil-num=1 en-affil=Graduate School of Natural Science and Technology, Okayama university kn-affil=岡山大学大学院自然科学研究科 END start-ver=1.4 cd-journal=joma no-vol= cd-vols= no-issue= article-no= start-page= end-page= dt-received= dt-revised= dt-accepted= dt-pub-year=2022 dt-pub=20220325 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=機械的伸長刺激が股関節唇の石灰化と軟骨基質の代謝を誘導し、変性の原因となる kn-title=Mechanical stretching induces calcification and cartilage matrix metabolism, causing degeneration of the acetabular labrum en-subtitle= kn-subtitle= en-abstract= kn-abstract= en-copyright= kn-copyright= en-aut-name=KawamuraYoushi en-aut-sei=Kawamura en-aut-mei=Youshi kn-aut-name=河村涌志 kn-aut-sei=河村 kn-aut-mei=涌志 aut-affil-num=1 ORCID= affil-num=1 en-affil=Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama University kn-affil=岡山大学大学院医歯薬学総合研究科 END start-ver=1.4 cd-journal=joma no-vol= cd-vols= no-issue= article-no= start-page= end-page= dt-received= dt-revised= dt-accepted= dt-pub-year=2021 dt-pub=20210924 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=刺激の多階層的な文脈操作による視覚対象認識メカニズムに関する研究 kn-title=Studies on mechanisms of visual object recognition by manipulating the context at hierarchical visual processing stages en-subtitle= kn-subtitle= en-abstract= kn-abstract= en-copyright= kn-copyright= en-aut-name=YuYiyang en-aut-sei=Yu en-aut-mei=Yiyang kn-aut-name=于溢洋 kn-aut-sei=于 kn-aut-mei=溢洋 aut-affil-num=1 ORCID= affil-num=1 en-affil=Graduate School of Natural Science and Technology, Okayama university kn-affil=岡山大学大学院自然科学研究科 END start-ver=1.4 cd-journal=joma no-vol= cd-vols= no-issue= article-no= start-page= end-page= dt-received= dt-revised= dt-accepted= dt-pub-year=2021 dt-pub=20210924 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=抗マラリア薬候補が有する幅広い抗ウイルス活性の作用機序解析 kn-title=Antiviral mechanism of preclinical antimalarial compounds possessing multiple antiviral activities en-subtitle= kn-subtitle= en-abstract= kn-abstract= en-copyright= kn-copyright= en-aut-name=GuWeilin en-aut-sei=Gu en-aut-mei=Weilin kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=1 ORCID= affil-num=1 en-affil=Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama University kn-affil=岡山大学大学院医歯薬学総合研究科 END start-ver=1.4 cd-journal=joma no-vol= cd-vols= no-issue= article-no= start-page= end-page= dt-received= dt-revised= dt-accepted= dt-pub-year=2021 dt-pub=20210325 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=原生生物タイヨウチュウRaphidocystis contractilisの急速な軸足収縮機構に関する研究 kn-title=Studies on mechanisms of rapid axopodial contraction in the centrohelid Raphidocystis contractilis en-subtitle= kn-subtitle= en-abstract= kn-abstract= en-copyright= kn-copyright= en-aut-name=IkedaRisa en-aut-sei=Ikeda en-aut-mei=Risa kn-aut-name=池田理佐 kn-aut-sei=池田 kn-aut-mei=理佐 aut-affil-num=1 ORCID= affil-num=1 en-affil=Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama University kn-affil=岡山大学大学院医歯薬学総合研究科 END start-ver=1.4 cd-journal=joma no-vol= cd-vols= no-issue= article-no= start-page= end-page= dt-received= dt-revised= dt-accepted= dt-pub-year=2021 dt-pub=20210325 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=視聴覚統合における注意負荷の調整メカニズムに関する心理物理学的研究 kn-title=Psychophysical Studies on Modulation Mechanism of Attentional Load in Audiovisual Integration en-subtitle= kn-subtitle= en-abstract= kn-abstract= en-copyright= kn-copyright= en-aut-name=RiTyintyin en-aut-sei=Ri en-aut-mei=Tyintyin kn-aut-name=李青青 kn-aut-sei=李 kn-aut-mei=青青 aut-affil-num=1 ORCID= affil-num=1 en-affil=Graduate School of Natural Science and Technology, Okayama university kn-affil=岡山大学大学院自然科学研究科 END start-ver=1.4 cd-journal=joma no-vol= cd-vols= no-issue= article-no= start-page= end-page= dt-received= dt-revised= dt-accepted= dt-pub-year=2021 dt-pub=20210325 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=ラット脳梗塞モデルにおける機械的血栓回収による直接的血管損傷と神経血管ユニットの破綻 kn-title=Direct arterial damage and neurovascular unit disruption by mechanical thrombectomy in a rat stroke model en-subtitle= kn-subtitle= en-abstract= kn-abstract= en-copyright= kn-copyright= en-aut-name=SasakiRyo en-aut-sei=Sasaki en-aut-mei=Ryo kn-aut-name=佐々木諒 kn-aut-sei=佐々木 kn-aut-mei=諒 aut-affil-num=1 ORCID= affil-num=1 en-affil=Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama University kn-affil=岡山大学大学院医歯薬学総合研究科 END start-ver=1.4 cd-journal=joma no-vol= cd-vols= no-issue= article-no= start-page= end-page= dt-received= dt-revised= dt-accepted= dt-pub-year=2020 dt-pub=20200925 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=触覚知覚学習の脳内処理メカニズムに関する神経心理学的研究 kn-title=Neuropsychological studies on human neural mechanism of tactile perceptual learning en-subtitle= kn-subtitle= en-abstract= kn-abstract= en-copyright= kn-copyright= en-aut-name=WangWu en-aut-sei=Wang en-aut-mei=Wu kn-aut-name=王武 kn-aut-sei=王 kn-aut-mei=武 aut-affil-num=1 ORCID= affil-num=1 en-affil=Graduate School of Natural Science and Technology, Okayama University kn-affil=岡山大学大学院自然科学研究科 END start-ver=1.4 cd-journal=joma no-vol= cd-vols= no-issue= article-no= start-page= end-page= dt-received= dt-revised= dt-accepted= dt-pub-year=2020 dt-pub=20200925 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=バイオインフォマティクス解析による骨細胞のメカノセンシティブ遺伝子と経路の解析 kn-title=Bioinformatic analysis of mechano-sensitive genes and pathways in osteocyte under the mechanical loadings en-subtitle= kn-subtitle= en-abstract= kn-abstract= en-copyright= kn-copyright= en-aut-name=WangZiyi en-aut-sei=Wang en-aut-mei=Ziyi kn-aut-name=王紫仪 kn-aut-sei=王 kn-aut-mei=紫仪 aut-affil-num=1 ORCID= affil-num=1 en-affil=Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama University kn-affil=岡山大学大学院医歯薬学総合研究科 END start-ver=1.4 cd-journal=joma no-vol= cd-vols= no-issue= article-no= start-page= end-page= dt-received= dt-revised= dt-accepted= dt-pub-year=2020 dt-pub=20200325 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=ウシ卵管上皮の繊毛・非繊毛細胞の増減機構の解明に関する研究 kn-title=Study on the mechanism of dynamic changes in the number of ciliated and non-ciliated cells in the bovine oviduct en-subtitle= kn-subtitle= en-abstract= kn-abstract= en-copyright= kn-copyright= en-aut-name=ItoSayaka en-aut-sei=Ito en-aut-mei=Sayaka kn-aut-name=伊藤さやか kn-aut-sei=伊藤 kn-aut-mei=さやか aut-affil-num=1 ORCID= affil-num=1 en-affil=Graduate School of Environmental and Life Science, Okayama University kn-affil=岡山大学大学院環境生命科学研究科 END start-ver=1.4 cd-journal=joma no-vol= cd-vols= no-issue= article-no= start-page= end-page= dt-received= dt-revised= dt-accepted= dt-pub-year=2020 dt-pub=20200325 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=オスのショウジョウバエにおける栄養環境依存的な妊性制御の分子機構 kn-title=Molecular mechanisms of nutrient-dependent regulation of fecundity in Drosophila males en-subtitle= kn-subtitle= en-abstract= kn-abstract= en-copyright= kn-copyright= en-aut-name=MatsukaMirai en-aut-sei=Matsuka en-aut-mei=Mirai kn-aut-name=松家未来 kn-aut-sei=松家 kn-aut-mei=未来 aut-affil-num=1 ORCID= affil-num=1 en-affil=Graduate School of Natural Science and Technology, Okayama University kn-affil=岡山大学大学院自然科学研究科 END start-ver=1.4 cd-journal=joma no-vol=51 cd-vols= no-issue=2-3 article-no= start-page=15 end-page=37 dt-received= dt-revised= dt-accepted= dt-pub-year=2020 dt-pub=20200319 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=The Development Strategies of Poland and the Engine of Polish Economic Growth kn-title=現代ポーランドの国家発展戦略と経済成長の原動力 en-subtitle= kn-subtitle= en-abstract= kn-abstract=　In this paper, authors analyze the changes in the national development strategies of the Polish government since the First World War, the state investment that became the driving force of economic development, the trends and positions of foreign capital, and the changes in the economic environment surrounding the Polish economy. 　In the Second Republic, economic liberalism was a widely supported philosophy in the business world and academic society. However, in order to support very weak economic fundamentals, the government seized the key industry and tried to rebuild the economy. Although foreign capital played a very important role in economic development, Polish people’s distrust in foreign capital was strong. After the Great Depression, the Central Industrial District（ CUP） was built under the leadership of the government. However, with the outbreak of World War II, the formation of a strong core industrial base was suspended.
　After the Second World War, the government initially aimed to build a Peoples Democracy system based on pluralism. However, when the Cold War sharpened, rapid industrialization and collectivization of agriculture were forced. The Stalinist economic development strategy failed in a few years. Nevertheless, from the end of the 1950s, mining development and industrialization based on the mechanical and chemical industries were carried out again. This industrialization of capital goods sector-oriented production has distorted the people’s consumer life. However, in the long run, it cannot be denied that the industrialization of that time became the basis for the formation of the wide promising fields of the Polish industry. Since 1970, an open economic strategy has been adopted. Modernization was attempted by introducing licenses from the west. However, new investments did not lead to expansion of export, and cumulative debt increased. During the economic crisis, the“ Solidarity” movement quickly grew into a national movement, but this did not lead to a fundamental economic system change. Economic reform was also attempted in the 1980s. However, the socialist economic system was unable to adapt to the new global economic system driven by innovation. The inflexible system lost its growth potential.
　After the collapse of socialist system in 1989, radical liberalization policies drastically improved economic imbalances, and the economic policy enabled high growth. During the transition period, foreign capital greatly contributed to growth. The automobile industry is a good example. This industry is associated with wide parts production. Many domestic intermediate goods manufacturers increased their orders, and their technical capabilities were rapidly improved through the guidance of foreign capital. In addition, export has improved significantly due to the expansion of production by foreign-affiliated companies. In contrast to the Second Republic, foreign capital played a major role in nurturing domestic industries. By the end of the 1990s, the Russian economy had had no effect on the Polish economy. At the transition period, the Polish industry shifted rapidly to the EU. At the same time, since the manufacturing field was the foundation of Polish growth, the impact of the 2007 global financial crisis wasn’t serious. Not only that, Poland maintained positive growth in 2008 as most countries in Europe fell into negative Currently, low-wage, low-value-added production based on FDI inflows and abundant labor force is the driving force for growth. In the medium and long term, the Polish economy cannot grow if it stays in the current subcontract production status of industrialized countries. The key to Poland’s escape from the “middle-income trap” is how to develop“ new Polish companies” that produce high-value-added products and services under global competition. en-copyright= kn-copyright= en-aut-name=TaguchiMasahiro en-aut-sei=Taguchi en-aut-mei=Masahiro kn-aut-name=田口雅弘 kn-aut-sei=田口 kn-aut-mei=雅弘 aut-affil-num=1 ORCID= en-aut-name=OkazakiTaku en-aut-sei=Okazaki en-aut-mei=Taku kn-aut-name=岡﨑拓 kn-aut-sei=岡﨑 kn-aut-mei=拓 aut-affil-num=2 ORCID= affil-num=1 en-affil=Graduate School of Humanities and Social Sciences, Okayama University kn-affil=岡山大学大学院社会文化科学研究科 affil-num=2 en-affil= kn-affil=常磐大学総合政策学部 END start-ver=1.4 cd-journal=joma no-vol= cd-vols= no-issue= article-no= start-page= end-page= dt-received= dt-revised= dt-accepted= dt-pub-year=2019 dt-pub=20190925 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=光化学的内在化（PCI）の機構解明，およびマウス初期胚へのRNAデリバリーへの応用 kn-title=The influence of physicochemical parameters on photochemical internalization (PCI) mechanism and application of PCI as a photo-dependent RNA delivery strategy to mouse embryo en-subtitle= kn-subtitle= en-abstract= kn-abstract= en-copyright= kn-copyright= en-aut-name=TET HTUT SOE en-aut-sei=TET HTUT SOE en-aut-mei= kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=1 ORCID= affil-num=1 en-affil=Graduate School of Natural Science and Technology, Okayama University kn-affil=岡山大学大学院自然科学研究科 END start-ver=1.4 cd-journal=joma no-vol= cd-vols= no-issue= article-no= start-page= end-page= dt-received= dt-revised= dt-accepted= dt-pub-year=2019 dt-pub=20190925 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=AZIN1 RNA編集の活性化は大腸癌癌関連線維芽細胞における浸潤能を促進させる新たな機序である kn-title=Activation of AZIN1 RNA editing is a novel mechanism that promotes invasive potential of cancer-associated fibroblasts in colorectal cancer en-subtitle= kn-subtitle= en-abstract= kn-abstract= en-copyright= kn-copyright= en-aut-name=TakedaSho en-aut-sei=Takeda en-aut-mei=Sho kn-aut-name=武田正 kn-aut-sei=武田 kn-aut-mei=正 aut-affil-num=1 ORCID= affil-num=1 en-affil=Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama University kn-affil=岡山大学大学院医歯薬学総合研究科 END start-ver=1.4 cd-journal=joma no-vol= cd-vols= no-issue= article-no= start-page= end-page= dt-received= dt-revised= dt-accepted= dt-pub-year=2019 dt-pub=20190325 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=ミリ秒から秒の時間スケールにおける時間予測の脳内メカニズムに関する研究 kn-title=Study on neural mechanisms of temporal expectation on a millisecond to second time scale en-subtitle= kn-subtitle= en-abstract= kn-abstract= en-copyright= kn-copyright= en-aut-name=XuZhihan en-aut-sei=Xu en-aut-mei=Zhihan kn-aut-name=徐之涵 kn-aut-sei=徐 kn-aut-mei=之涵 aut-affil-num=1 ORCID= affil-num=1 en-affil=Graduate School of Natural Science and Technology, Okayama University kn-affil=岡山大学大学院自然科学研究科 END start-ver=1.4 cd-journal=joma no-vol= cd-vols= no-issue= article-no= start-page= end-page= dt-received= dt-revised= dt-accepted= 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affil-num=1 en-affil=Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama University kn-affil=岡山大学大学院医歯薬学総合研究科 END start-ver=1.4 cd-journal=joma no-vol= cd-vols= no-issue= article-no= start-page= end-page= dt-received= dt-revised= dt-accepted= dt-pub-year=2017 dt-pub=20171227 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=JAK阻害剤のメカニカルストレスによるヒト軟骨細胞からの蛋白分解酵素発現抑制 kn-title=Inhibitory effect of JAK inhibitor on mechanical stress-induced protease expression by human articular chondrocytes en-subtitle= kn-subtitle= en-abstract= kn-abstract= en-copyright= kn-copyright= en-aut-name=MachidaTakahiro en-aut-sei=Machida en-aut-mei=Takahiro kn-aut-name=町田崇博 kn-aut-sei=町田 kn-aut-mei=崇博 aut-affil-num=1 ORCID= affil-num=1 en-affil=Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama University kn-affil=岡山大学大学院医歯薬学総合研究科 END start-ver=1.4 cd-journal=joma no-vol= cd-vols= no-issue= article-no= start-page= end-page= dt-received= dt-revised= 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en-aut-sei=Chen en-aut-mei=Zhi Chang kn-aut-name=陳志長 kn-aut-sei=陳 kn-aut-mei=志長 aut-affil-num=1 ORCID= affil-num=1 en-affil= kn-affil=岡山大学 END start-ver=1.4 cd-journal=joma no-vol= cd-vols= no-issue= article-no= start-page= end-page= dt-received= dt-revised= dt-accepted= dt-pub-year=2013 dt-pub=20130930 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=ヒトの視覚物体知覚脳機能メカニズムに関するfMRI研究 kn-title=fMRI Studies on the Human Brain Mechanism of Visual Object Perception en-subtitle= kn-subtitle= en-abstract= kn-abstract= en-copyright= kn-copyright= en-aut-name=WangBin en-aut-sei=Wang en-aut-mei=Bin kn-aut-name=王彬 kn-aut-sei=王 kn-aut-mei=彬 aut-affil-num=1 ORCID= affil-num=1 en-affil= kn-affil=岡山大学 END start-ver=1.4 cd-journal=joma no-vol= cd-vols= no-issue= article-no= start-page= end-page= dt-received= dt-revised= dt-accepted= dt-pub-year=2013 dt-pub=20130930 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=AlPO4高圧相の第一原理法による研究：圧縮機構、誘電性、格子力学、熱力学的性質と相図 kn-title=First-principles study on high-pressure phases of AlPO4 compound: compression mechanism, dielectric properties, lattice dynamics, thermodynamics properties, and phase diagram en-subtitle= kn-subtitle= en-abstract= kn-abstract= en-copyright= kn-copyright= en-aut-name=WangRiping en-aut-sei=Wang en-aut-mei=Riping kn-aut-name=汪日平 kn-aut-sei=汪 kn-aut-mei=日平 aut-affil-num=1 ORCID= affil-num=1 en-affil= kn-affil=岡山大学 END start-ver=1.4 cd-journal=joma no-vol= cd-vols= no-issue= article-no= start-page= end-page= dt-received= dt-revised= dt-accepted= dt-pub-year=2013 dt-pub=20130325 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=内耳蝸牛血管条における糖輸送機構に関する研究 kn-title=Studies on glucose transport mechanisms in the cochlear stria vascularis en-subtitle= kn-subtitle= en-abstract= kn-abstract= en-copyright= kn-copyright= en-aut-name=EdamatsuMidori en-aut-sei=Edamatsu en-aut-mei=Midori kn-aut-name=枝松緑 kn-aut-sei=枝松 kn-aut-mei=緑 aut-affil-num=1 ORCID= affil-num=1 en-affil= kn-affil=岡山大学 END start-ver=1.4 cd-journal=joma no-vol= cd-vols= no-issue= article-no= start-page= end-page= dt-received= dt-revised= dt-accepted= dt-pub-year=2013 dt-pub=20130325 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=培養ヒト軟骨細胞においてヒストン脱アセチル化酵素阻害薬は、メカニカルストレスにより亢進したRUNX-2とADAMTS-5の発現を、MAPK経路を阻害することにより抑制する kn-title=Histone deacetylase inhibitors suppress mechanical stress-induced expression of RUNX-2 and ADAMTS-5 through the inhibition of the MAPK signaling pathway in cultured human chondrocytes en-subtitle= kn-subtitle= en-abstract= kn-abstract= en-copyright= kn-copyright= en-aut-name=SaitoTaichi en-aut-sei=Saito en-aut-mei=Taichi kn-aut-name=齋藤太一 kn-aut-sei=齋藤 kn-aut-mei=太一 aut-affil-num=1 ORCID= affil-num=1 en-affil= kn-affil=岡山大学 END start-ver=1.4 cd-journal=joma no-vol= cd-vols= no-issue= article-no= start-page= end-page= dt-received= dt-revised= dt-accepted= dt-pub-year=2013 dt-pub=20130325 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=新規浸潤性グリオーマモデルを用いたcilengitideの2種類の抗腫瘍機序の検討 kn-title=Bimodal anti-glioma mechanisms of cilengitide demonstrated by novel invasive glioma models en-subtitle= kn-subtitle= en-abstract= kn-abstract= en-copyright= kn-copyright= en-aut-name=OnishiManabu en-aut-sei=Onishi en-aut-mei=Manabu kn-aut-name=大西学 kn-aut-sei=大西 kn-aut-mei=学 aut-affil-num=1 ORCID= affil-num=1 en-affil= kn-affil=岡山大学 END start-ver=1.4 cd-journal=joma no-vol= cd-vols= no-issue= article-no= start-page= end-page= dt-received= dt-revised= dt-accepted= dt-pub-year=2012 dt-pub=20120927 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=医薬候補の探索を目的とするキノリン-インドール系分子の作用機構に基づく分子設計，合成，および活性評価に関する研究 kn-title=Studies on the Mechanism-Inspired Design, Synthesis, and Biological Evaluation of Quinoline-Indole-Assembled Molecules for Drug Candidates en-subtitle= kn-subtitle= en-abstract= kn-abstract= en-copyright= kn-copyright= en-aut-name=WangLi en-aut-sei=Wang en-aut-mei=Li kn-aut-name=王力 kn-aut-sei=王 kn-aut-mei=力 aut-affil-num=1 ORCID= affil-num=1 en-affil= kn-affil=岡山大学 END start-ver=1.4 cd-journal=joma no-vol= cd-vols= no-issue= article-no= start-page= end-page= dt-received= dt-revised= dt-accepted= dt-pub-year=2012 dt-pub=20120927 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=ヒト癌細胞におけるトラスツヅマブ耐性機構の解析とHER2細胞外ドメイン発現によるADCC活性増強を介した感受性誘導 kn-title=Mechanism of resistance to trastuzumab and molecular sensitization via ADCC activation by exogenous expression of HER2-extracellular domain in human cancer cells en-subtitle= kn-subtitle= en-abstract= kn-abstract= en-copyright= kn-copyright= en-aut-name=YoshidaRyosuke en-aut-sei=Yoshida en-aut-mei=Ryosuke kn-aut-name=吉田亮介 kn-aut-sei=吉田 kn-aut-mei=亮介 aut-affil-num=1 ORCID= affil-num=1 en-affil= kn-affil=岡山大学 END start-ver=1.4 cd-journal=joma no-vol= cd-vols= no-issue= article-no= start-page= end-page= dt-received= dt-revised= dt-accepted= dt-pub-year=2012 dt-pub=20120630 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=遺伝子工学的に操作したアデノウイルスを用いた腫瘍特異的なp53発現誘導におけるE1A依存的p21およびMDM2の抑制を介した新たなアポトーシス誘導機構 kn-title=A novel apoptotic mechanism of genetically engineered adenovirus-mediated tumour-specific p53 overexpression through E1A-dependent p21 and MDM2 suppression en-subtitle= kn-subtitle= en-abstract= kn-abstract= en-copyright= kn-copyright= en-aut-name=YamasakiYasumoto en-aut-sei=Yamasaki en-aut-mei=Yasumoto kn-aut-name=山崎泰源 kn-aut-sei=山崎 kn-aut-mei=泰源 aut-affil-num=1 ORCID= affil-num=1 en-affil= kn-affil=岡山大学 END start-ver=1.4 cd-journal=joma no-vol= cd-vols= no-issue= article-no= start-page= end-page= dt-received= dt-revised= dt-accepted= dt-pub-year=2012 dt-pub=20120323 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=Pseudomonas syringae pv. tabaci 6605の表層繊維タンパク質フラジェリンとピリンの糖鎖修飾機構と機能 kn-title=Mechanism and function of glycosylation of surface filamentous proteins flagellin and pilin in Pseudomonas syringae pv. tabaci 6605 en-subtitle= kn-subtitle= en-abstract= kn-abstract= en-copyright= kn-copyright= en-aut-name=Linh ChiNguyen en-aut-sei=Linh Chi en-aut-mei=Nguyen kn-aut-name= kn-aut-sei= kn-aut-mei= aut-affil-num=1 ORCID= affil-num=1 en-affil= kn-affil=岡山大学 END start-ver=1.4 cd-journal=joma no-vol= cd-vols= no-issue= article-no= start-page= end-page= dt-received= dt-revised= dt-accepted= dt-pub-year=2012 dt-pub=20120323 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=機能的核磁気共鳴画像法を用いた表語文字言語処理のメカニズムに関する研究 kn-title=Studies on the Mechanism of Logographic Language Processing by Functional Magnetic Resonance Imaging en-subtitle= kn-subtitle= en-abstract= kn-abstract= en-copyright= kn-copyright= en-aut-name=LiXiujun en-aut-sei=Li en-aut-mei=Xiujun kn-aut-name=李修軍 kn-aut-sei=李 kn-aut-mei=修軍 aut-affil-num=1 ORCID= affil-num=1 en-affil= kn-affil=岡山大学 END start-ver=1.4 cd-journal=joma no-vol= cd-vols= no-issue= article-no= start-page= end-page= dt-received= dt-revised= dt-accepted= dt-pub-year=2012 dt-pub=20120323 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=半月板inner細胞におけるメカニカルストレスによるCOL2A1発現の増加はSOX9によりクロマチンレベルで調節される kn-title=Mechanical Stretch Enhances COL2A1 Expression on Chromatin by Inducing SOX9 Nuclear Translocalization in Inner Meniscus Cells en-subtitle= kn-subtitle= en-abstract= kn-abstract= en-copyright= kn-copyright= en-aut-name=KanazawaTomoko en-aut-sei=Kanazawa en-aut-mei=Tomoko kn-aut-name=金沢智子 kn-aut-sei=金沢 kn-aut-mei=智子 aut-affil-num=1 ORCID= affil-num=1 en-affil= kn-affil=岡山大学 END start-ver=1.4 cd-journal=joma no-vol= cd-vols= no-issue= article-no= start-page= end-page= dt-received= dt-revised= dt-accepted= dt-pub-year=2012 dt-pub=20120323 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=ボツリヌスE型毒素は、A型毒素と異なるメカニズムによりCaco-2細胞へ結合する kn-title=Clostridium botulinum Type E Toxins Bind to Caco-2 Cells by a Different Mechanism from That of Type A Toxins en-subtitle= kn-subtitle= en-abstract= kn-abstract= en-copyright= kn-copyright= en-aut-name=ZhangKai en-aut-sei=Zhang en-aut-mei=Kai kn-aut-name=張凱 kn-aut-sei=張 kn-aut-mei=凱 aut-affil-num=1 ORCID= affil-num=1 en-affil= kn-affil=岡山大学 END start-ver=1.4 cd-journal=joma no-vol= cd-vols= no-issue= article-no= start-page= end-page= dt-received= dt-revised= dt-accepted= dt-pub-year=2012 dt-pub=20120323 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=周期的伸張負荷がヒト前十字靭帯細胞のCCN2/CTGF発現を活性化する kn-title=Mechanical stretch increases CCN2/CTGF expression in anterior cruciate ligament-derived cells en-subtitle= kn-subtitle= en-abstract= kn-abstract= en-copyright= kn-copyright= en-aut-name=MiyakeYoshiaki en-aut-sei=Miyake en-aut-mei=Yoshiaki kn-aut-name=三宅由晃 kn-aut-sei=三宅 kn-aut-mei=由晃 aut-affil-num=1 ORCID= affil-num=1 en-affil= kn-affil=岡山大学 END start-ver=1.4 cd-journal=joma no-vol= cd-vols= no-issue= article-no= start-page= end-page= dt-received= dt-revised= dt-accepted= dt-pub-year=2012 dt-pub=20120323 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=新しいC型肝炎ウイルス複製細胞システムを用いたリバビリンの作用機序の解析 kn-title=Mechanism of action of ribavirin in a novel hepatitis C virus replication cell system en-subtitle= kn-subtitle= en-abstract= kn-abstract= en-copyright= kn-copyright= en-aut-name=MoriKyoko en-aut-sei=Mori en-aut-mei=Kyoko kn-aut-name=森京子 kn-aut-sei=森 kn-aut-mei=京子 aut-affil-num=1 ORCID= affil-num=1 en-affil= kn-affil=岡山大学 END start-ver=1.4 cd-journal=joma no-vol= cd-vols= no-issue= article-no= start-page= end-page= dt-received= dt-revised= dt-accepted= dt-pub-year=2012 dt-pub=20120323 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=自己集合性ペプチドハイドロゲル内で三次元培養された細胞への機械刺激 kn-title=The mechanical stimulation of cells in 3D culture within a self-assembling peptide hydrogel en-subtitle= kn-subtitle= en-abstract= kn-abstract= en-copyright= kn-copyright= en-aut-name=NagaiYusuke en-aut-sei=Nagai en-aut-mei=Yusuke kn-aut-name=永井祐介 kn-aut-sei=永井 kn-aut-mei=祐介 aut-affil-num=1 ORCID= affil-num=1 en-affil= kn-affil=岡山大学 END start-ver=1.4 cd-journal=joma no-vol= cd-vols= no-issue= article-no= start-page= end-page= dt-received= dt-revised= dt-accepted= dt-pub-year=2011 dt-pub=20110930 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=ウシ黄体機能の周期的変化と黄体内血管分布変化ならびにその制御機構に関する研究 kn-title=Changes in the function and density of luteal vasculature throughout the estrous cycle and its regulatory mechanism in cattle en-subtitle= kn-subtitle= en-abstract= kn-abstract= en-copyright= kn-copyright= en-aut-name=HojoTakuo en-aut-sei=Hojo en-aut-mei=Takuo kn-aut-name=法上拓生 kn-aut-sei=法上 kn-aut-mei=拓生 aut-affil-num=1 ORCID= affil-num=1 en-affil= kn-affil=岡山大学 END start-ver=1.4 cd-journal=joma no-vol= cd-vols= no-issue= article-no= start-page= end-page= dt-received= dt-revised= dt-accepted= dt-pub-year=2011 dt-pub=20110930 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=ペルオキシゾーム増殖因子活性化受容体δの活性化はストレプトゾトシン誘発糖尿病マウスにおいて抗炎症効果により糖尿病性腎症の進展を抑制する kn-title=Activation of Peroxisome 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cd-journal=joma no-vol= cd-vols= no-issue= article-no= start-page= end-page= dt-received= dt-revised= dt-accepted= dt-pub-year=2011 dt-pub=20110325 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=キイロショウジョウバエ概日時計機構の行動学的および細胞学的解析 kn-title=Behavioral and cellular dissection of the circadian clock mechanism in the fruit fly, Drosophila melanogaster en-subtitle= kn-subtitle= en-abstract= kn-abstract= en-copyright= kn-copyright= en-aut-name=UmezakiYujiro en-aut-sei=Umezaki en-aut-mei=Yujiro kn-aut-name=梅崎勇次郎 kn-aut-sei=梅崎 kn-aut-mei=勇次郎 aut-affil-num=1 ORCID= affil-num=1 en-affil= kn-affil=岡山大学 END start-ver=1.4 cd-journal=joma no-vol= cd-vols= no-issue= article-no= start-page= end-page= dt-received= dt-revised= dt-accepted= dt-pub-year=2011 dt-pub=20110325 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=抗体遺伝子の高頻度突然変異機構とその生物工学的応用に関する研究 kn-title=Studies on the mechanism of hypermutation in antibody genes and its biotechnological application en-subtitle= kn-subtitle= en-abstract= kn-abstract= en-copyright= kn-copyright= en-aut-name=KanehiroYuichi en-aut-sei=Kanehiro en-aut-mei=Yuichi kn-aut-name=金広優一 kn-aut-sei=金広 kn-aut-mei=優一 aut-affil-num=1 ORCID= affil-num=1 en-affil= kn-affil=岡山大学 END start-ver=1.4 cd-journal=joma no-vol= cd-vols= no-issue= article-no= start-page= end-page= dt-received= dt-revised= dt-accepted= dt-pub-year=2011 dt-pub=20110325 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=触覚デバイス開発と指の把持動作における長さ知覚メカニズムに関する研究 kn-title=Development of Haptic Device and Investigation on Human Mechanism of Length Perception by Fingers Grasping en-subtitle= kn-subtitle= en-abstract= kn-abstract= en-copyright= kn-copyright= en-aut-name= en-aut-sei= en-aut-mei= kn-aut-name=王海波 kn-aut-sei=王 kn-aut-mei=海波 aut-affil-num=1 ORCID= affil-num=1 en-affil= kn-affil=岡山大学 END start-ver=1.4 cd-journal=joma no-vol= cd-vols= no-issue= article-no= start-page= end-page= dt-received= dt-revised= dt-accepted= dt-pub-year=2011 dt-pub=20110325 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=機能的核磁気共鳴画像法を用いたヒトの広視野の視覚メカニズムに関する研究 kn-title=Studies on the Human Visual Mechanism of Wide-field by Functional Magnetic Resonance Imaging en-subtitle= kn-subtitle= en-abstract= kn-abstract= en-copyright= kn-copyright= en-aut-name= en-aut-sei= en-aut-mei= kn-aut-name=閻天翼 kn-aut-sei=閻 kn-aut-mei=天翼 aut-affil-num=1 ORCID= affil-num=1 en-affil= kn-affil=岡山大学 END start-ver=1.4 cd-journal=joma no-vol= cd-vols= no-issue= article-no= start-page= end-page= dt-received= dt-revised= dt-accepted= dt-pub-year=2010 dt-pub=20101231 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=組織球性リンパ腫U937細胞における5-アミノレブリン酸を用いた光力学的作用による細胞死の機構とフェロキラターゼ阻害剤によるその促進 kn-title=Mechanism of cell death by 5-aminolevulinic acid-based photodynamic action and its enhancement by ferrochelatase inhibitors in human histiocytic lymphoma cell line U937 en-subtitle= kn-subtitle= en-abstract= kn-abstract= en-copyright= kn-copyright= en-aut-name=AmoTakashi en-aut-sei=Amo en-aut-mei=Takashi kn-aut-name=天羽隆 kn-aut-sei=天羽 kn-aut-mei=隆 aut-affil-num=1 ORCID= affil-num=1 en-affil= kn-affil=岡山大学 END start-ver=1.4 cd-journal=joma no-vol= cd-vols= no-issue= article-no= start-page= end-page= dt-received= dt-revised= dt-accepted= dt-pub-year=2010 dt-pub=20100325 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=ウシ黄体由来血管内皮細胞におけるプロスタグランジン F(2α) の作用機構に関する研究 kn-title=STUDIES ON MECHANISMS OF PROSTAGLANDIN F(2α) ACTION IN BOVINE LUTEAL ENDOTHELIAL CELLS en-subtitle= kn-subtitle= en-abstract= kn-abstract= en-copyright= kn-copyright= en-aut-name=LeeSeunghyung en-aut-sei=Lee en-aut-mei=Seunghyung kn-aut-name=イスンヒョン kn-aut-sei=イ kn-aut-mei=スンヒョン aut-affil-num=1 ORCID= affil-num=1 en-affil= kn-affil=岡山大学 END start-ver=1.4 cd-journal=joma no-vol= cd-vols= no-issue= article-no= start-page= end-page= dt-received= dt-revised= dt-accepted= dt-pub-year=2010 dt-pub=20100325 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=事象関連電位による人間の視聴覚統合メカニズムに関する研究 kn-title=Study on Human Mechanism of Audiovisual Integration by Event-related Potentials en-subtitle= kn-subtitle= en-abstract= kn-abstract= en-copyright= kn-copyright= en-aut-name= en-aut-sei= en-aut-mei= kn-aut-name=李奇 kn-aut-sei=李 kn-aut-mei=奇 aut-affil-num=1 ORCID= affil-num=1 en-affil= kn-affil=岡山大学 END start-ver=1.4 cd-journal=joma no-vol= cd-vols= no-issue= article-no= start-page= end-page= dt-received= dt-revised= dt-accepted= dt-pub-year=2010 dt-pub=20100325 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=球状シリカフィラー添加による合着用グラスアイオノマーセントの物性改良 kn-title=Mechanical properties of a resin-modified glass-ionomer cement for luting:effect of adding spherical silica filler en-subtitle= kn-subtitle= en-abstract= kn-abstract= en-copyright= kn-copyright= en-aut-name=ELihua en-aut-sei=E en-aut-mei=Lihua kn-aut-name=鄂麗華 kn-aut-sei=鄂 kn-aut-mei=麗華 aut-affil-num=1 ORCID= affil-num=1 en-affil= kn-affil=岡山大学 END start-ver=1.4 cd-journal=joma no-vol= cd-vols= no-issue= article-no= start-page= end-page= dt-received= dt-revised= dt-accepted= dt-pub-year=2010 dt-pub=20100325 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=前十字靭帯-骨軟骨結合部における細胞生物学的特徴　-メカニカルストレスによる細胞接着とcollagen発現変化の検討- kn-title=Mechanical stretch stimulates integrin αVβ3 - mediated collagen expression in human anterior cruciate ligament cells en-subtitle= kn-subtitle= en-abstract= kn-abstract= en-copyright= kn-copyright= en-aut-name=TetsunagaTomonori en-aut-sei=Tetsunaga en-aut-mei=Tomonori kn-aut-name=鉄永智紀 kn-aut-sei=鉄永 kn-aut-mei=智紀 aut-affil-num=1 ORCID= affil-num=1 en-affil= kn-affil=岡山大学 END start-ver=1.4 cd-journal=joma no-vol= cd-vols= no-issue= article-no= start-page= end-page= dt-received= dt-revised= dt-accepted= dt-pub-year=2009 dt-pub=20090325 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=3-ニトロプロピオン酸誘導性単離ミトコンドリア膜透過性遷移の機構とL-カルニチンによるその抑制 kn-title=Mechanism of 3-nitropropionic acid-induced membrane permeability transition of isolated mitochondria and its suppression by L-carnitine en-subtitle= kn-subtitle= en-abstract= kn-abstract= en-copyright= kn-copyright= en-aut-name=NishimuraMakoto en-aut-sei=Nishimura en-aut-mei=Makoto kn-aut-name=西村眞 kn-aut-sei=西村 kn-aut-mei=眞 aut-affil-num=1 ORCID= affil-num=1 en-affil= kn-affil=岡山大学 END start-ver=1.4 cd-journal=joma no-vol= cd-vols= no-issue= article-no= start-page= end-page= dt-received= dt-revised= dt-accepted= dt-pub-year=2009 dt-pub=20090325 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=タンボコオロギにおける光周測時機構の生理学的・分子生物学的解析 kn-title=Physiological and molecular analysis of the photoperiodic time-measurement mechanism in the cricket, Modicogryllus siamensis en-subtitle= kn-subtitle= en-abstract= kn-abstract= en-copyright= kn-copyright= en-aut-name=SakamotoTomoaki en-aut-sei=Sakamoto en-aut-mei=Tomoaki kn-aut-name=坂本智昭 kn-aut-sei=坂本 kn-aut-mei=智昭 aut-affil-num=1 ORCID= affil-num=1 en-affil= kn-affil=岡山大学 END start-ver=1.4 cd-journal=joma no-vol= cd-vols= no-issue= article-no= start-page= end-page= dt-received= dt-revised= dt-accepted= dt-pub-year=2008 dt-pub=20080930 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=キイロショウジョウバエの蛹化のタイミングを決める生物タイマーの分子機構 kn-title=Molecular mechanism of a biological timer system that controls pupation timing in Drosophila melanogaster en-subtitle= kn-subtitle= en-abstract= kn-abstract= en-copyright= kn-copyright= en-aut-name= en-aut-sei= en-aut-mei= kn-aut-name=MOUSTAFA MOHAMEDHEMIDA SARHAN kn-aut-sei=MOUSTAFA MOHAMED kn-aut-mei=HEMIDA SARHAN aut-affil-num=1 ORCID= affil-num=1 en-affil= kn-affil=岡山大学 END start-ver=1.4 cd-journal=joma no-vol= cd-vols= no-issue= article-no= start-page= end-page= dt-received= dt-revised= dt-accepted= dt-pub-year=2008 dt-pub=20080325 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=マイクロアレイを用いた高等植物における病害および環境ストレス応答機構の解明 kn-title=Transcriptome analysis of plant defense mechanisms against biotic and abiotic stresses using a microarray en-subtitle= kn-subtitle= en-abstract= kn-abstract= en-copyright= kn-copyright= en-aut-name=NarusakaMari en-aut-sei=Narusaka en-aut-mei=Mari kn-aut-name=鳴坂真理 kn-aut-sei=鳴坂 kn-aut-mei=真理 aut-affil-num=1 ORCID= affil-num=1 en-affil= kn-affil=岡山大学 END start-ver=1.4 cd-journal=joma no-vol= cd-vols= no-issue= article-no= start-page= end-page= dt-received= dt-revised= dt-accepted= dt-pub-year=2007 dt-pub=20071231 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=HL-60細胞におけるA23187誘導アポトーシスのメカニズム：NADPHオキシダーゼではなくミトコンドリア膜透過性遷移への依存 kn-title=Mechanism of A23187-Induced Apoptosis in HL-60 Cells: Dependency on Mitochondrial Permeability Transition but Not on NADPH Oxidase en-subtitle= kn-subtitle= en-abstract= kn-abstract= en-copyright= kn-copyright= en-aut-name=KajitaniNoriko en-aut-sei=Kajitani en-aut-mei=Noriko kn-aut-name=梶谷典子 kn-aut-sei=梶谷 kn-aut-mei=典子 aut-affil-num=1 ORCID= affil-num=1 en-affil= kn-affil=岡山大学 END start-ver=1.4 cd-journal=joma no-vol= cd-vols= no-issue= article-no= start-page= end-page= dt-received= dt-revised= dt-accepted= dt-pub-year=2008 dt-pub=20080325 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=sks突然変異マウスにおける精子形成異常の分子機構に関する研究 kn-title=Study on the molecular mechanisms of the defect of spermatogenesis in the sks mutant mice en-subtitle= kn-subtitle= en-abstract= kn-abstract= en-copyright= kn-copyright= en-aut-name=AkiyamaKoyo en-aut-sei=Akiyama en-aut-mei=Koyo kn-aut-name=秋山耕陽 kn-aut-sei=秋山 kn-aut-mei=耕陽 aut-affil-num=1 ORCID= affil-num=1 en-affil= kn-affil=岡山大学 END start-ver=1.4 cd-journal=joma no-vol= cd-vols= no-issue= article-no= start-page= end-page= dt-received= dt-revised= dt-accepted= dt-pub-year=2007 dt-pub=20070930 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=ビタミンB(12)補酵素関与グリセロールデヒドラターゼの再活性化因子の同定と性質および作用機作 kn-title=Identification, properties, and action mechanism of a reactivating factor for adenosylcobalamin-dependent glycerol dehydratase en-subtitle= kn-subtitle= en-abstract= kn-abstract= en-copyright= kn-copyright= en-aut-name=KajiuraHideki en-aut-sei=Kajiura en-aut-mei=Hideki kn-aut-name=梶浦英樹 kn-aut-sei=梶浦 kn-aut-mei=英樹 aut-affil-num=1 ORCID= affil-num=1 en-affil= kn-affil=岡山大学 END start-ver=1.4 cd-journal=joma no-vol= cd-vols= no-issue= article-no= start-page= end-page= dt-received= dt-revised= dt-accepted= dt-pub-year=2007 dt-pub=20070930 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=Ehマウスにおける口蓋裂の発生機構および関連遺伝子に関する研究 kn-title=Studies on the developmental mechanism and associated genes for cleft palate of Eh mice en-subtitle= kn-subtitle= en-abstract= kn-abstract= en-copyright= kn-copyright= en-aut-name=KatayamaKentaro en-aut-sei=Katayama en-aut-mei=Kentaro kn-aut-name=片山健太郎 kn-aut-sei=片山 kn-aut-mei=健太郎 aut-affil-num=1 ORCID= affil-num=1 en-affil= kn-affil=岡山大学 END start-ver=1.4 cd-journal=joma no-vol= cd-vols= no-issue= article-no= start-page= end-page= dt-received= dt-revised= dt-accepted= dt-pub-year=2007 dt-pub=20070630 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=脂肪肝マウスの肝切除後の再生障害のメカニズム kn-title=Mechanism of impaired regeneration of fatty liver in mouse partial hepatectomy model en-subtitle= kn-subtitle= en-abstract= kn-abstract= en-copyright= kn-copyright= en-aut-name=MurataHiroshi en-aut-sei=Murata en-aut-mei=Hiroshi kn-aut-name=村田宏 kn-aut-sei=村田 kn-aut-mei=宏 aut-affil-num=1 ORCID= affil-num=1 en-affil= kn-affil=岡山大学 END start-ver=1.4 cd-journal=joma no-vol= cd-vols= no-issue= article-no= start-page= end-page= dt-received= dt-revised= dt-accepted= dt-pub-year=2007 dt-pub=20070323 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=球状シリカフィラー添加によるレジンモディファイドグラスアイオノマーセメントの機械的強さの改良 kn-title=EFFECTS OF SPHERICAL SIRICA FILLER ADDITION ON IMPROVING THE MECHANICAL CHARACTERISTICS OF REZIN-MODIFIED GLASS-IONOMER CEMENT en-subtitle= kn-subtitle= en-abstract= kn-abstract= en-copyright= kn-copyright= en-aut-name=HatanakaKenji en-aut-sei=Hatanaka en-aut-mei=Kenji kn-aut-name=畑中乾志 kn-aut-sei=畑中 kn-aut-mei=乾志 aut-affil-num=1 ORCID= affil-num=1 en-affil= kn-affil=岡山大学 END start-ver=1.4 cd-journal=joma no-vol= cd-vols= no-issue= article-no= start-page= end-page= dt-received= dt-revised= dt-accepted= dt-pub-year=2007 dt-pub=20070323 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=モルヒネ単回投与ラットにおけるナロキソン誘発場所嫌悪性試験に対するグルタミン酸受容体の関与 kn-title=Effect of glutamate receptor antagonists on place aversion induced by naloxone in single-dose morphine-treated rats en-subtitle= kn-subtitle= en-abstract= kn-abstract=The neurobiological mechanism underlying the negative motivational component of withdrawal from acute opiate dependence is far from understood. Our objectives were to determine whether the glutamatergic system is involved in the motivational component of morphine withdrawal in acutely dependent rats and such an involvement is associated with dopaminergic neurotransmission. We examined the effects of various kinds of glutamate receptor antagonists on conditioned place aversion (CPA) induced by naloxone-precipitated withdrawal from a single morphine exposure 24 h before. Furthermore, the influence of pretreatment with the dopamine receptor antagonist haloperidol on those effects of glutamate receptor antagonists was also investigated. CPA was attenuated in a dose-dependent manner by all glutamate receptor antagonists examined including the NMDA receptor antagonists (+)-5-methyl-10,11-dihydro-5H-dibenzo[a,d]cyclo-hepten-5,10-imine maleate (MK-801) and phencyclidine hydrochloride (PCP), AMPA receptor antagonist 1-(4-aminophenyl)4-methyl-7,8-methylenedioxy-5H-2,3-benzodiazepine hydrochloride (GYKI 52466), and metabotropic receptor antagonists (+/-)-2-amino-3-phosphonopropionic acid (AP-3) and (+/-)-alpha-methyl-4-carboxyphenylglycine (MCPG). The effects of MK-801, GYKI 52466 and MCPG were blocked by haloperidol.These results suggest that the glutamatergic system involving multiple classes of receptors plays a role in the motivational component of withdrawal from acute morphine dependence, and the function of the glutamatergic system would be closely associated with dopaminergic neurotransmission. en-copyright= kn-copyright= en-aut-name=KawasakiYoichi en-aut-sei=Kawasaki en-aut-mei=Yoichi kn-aut-name=河崎陽一 kn-aut-sei=河崎 kn-aut-mei=陽一 aut-affil-num=1 ORCID= affil-num=1 en-affil= kn-affil=岡山大学 en-keyword=morphine kn-keyword=morphine en-keyword=acute dependence kn-keyword=acute dependence en-keyword=naloxone kn-keyword=naloxone en-keyword=withdrawal kn-keyword=withdrawal en-keyword=conditioned place aversion kn-keyword=conditioned place aversion en-keyword=glutamate receptor antagonist kn-keyword=glutamate receptor antagonist en-keyword=dopamine kn-keyword=dopamine END start-ver=1.4 cd-journal=joma no-vol= cd-vols= no-issue= article-no= start-page= end-page= dt-received= dt-revised= dt-accepted= dt-pub-year=2007 dt-pub=20070323 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=ヘリコバクター・ピロリ熱ショック蛋白60は、単核球細胞中でのTLR2とMAPキナーゼ経路を介し，サイトカインIL-8の分泌を引き起こす kn-title=Helicobacter pylori heat-shock protein 60 induces interleukin-8 via a toll-like receptor (TLR) 2 and mitogen-activated protein (MAP) kinase pathway in human monocytes en-subtitle= kn-subtitle= en-abstract= kn-abstract=Previous reports have indicated that Helicobacter pylori heat-shock protein 60 (H. pylori-HSP60), as an immunodominant antigen, induces interleukin (IL)-8 production in human monocytes. The exact mechanism by which H. pylori-HSP60 induces IL-8 production in monocytes has not been fully elucidated. In the present study, the downstream pathway by which H. pylori-HSP60 induces IL-8 secretion in human monocytic cell lines was investigated. Intact H. pylori, heat-killed H. pylori and H. pylori recombinant HSP60 (rHpHSP60) all induced the secretion of IL-8 and the activation of mitogen-activated protein kinase (MAPK), extracellular signal-regulated kinase (ERK) and p38, but not c-Jun N-terminal kinase (JNK), up to 24 h in NOMO1 cells. The specific inhibitors PD98059 and U0126 (for ERK1/2 signalling) and SB203580 (for p38 MAPK signalling) down-regulated IL-8 secretion from rHpHSP60-treated NOMO1 cells. An anti-Toll-like receptor (TLR)2 antibody or TLR2 small interfering RNA (siRNA) partially inhibited the secretion of IL-8, and anti-TLR2 antibody also suppressed activation of ERK and p38 MAPK in rHpHSP60-treated NOMO1 cells. These reactions were associated with nuclear factor-kappaB (NF-kappaB)-mediated transcriptional activation, since U0126, SB203580 and the anti-TLR2 antibody decreased NF-kappaB activation. Taken together, the results suggest that ERK and p38 MAPK signalling linked to the TLR2 recognition receptor in human monocytes may be an important pathway in H. pylori-HSP60-induced IL-8 secretion. en-copyright= kn-copyright= en-aut-name=ZhaoYing en-aut-sei=Zhao en-aut-mei=Ying kn-aut-name=趙瑩 kn-aut-sei=趙 kn-aut-mei=瑩 aut-affil-num=1 ORCID= affil-num=1 en-affil= kn-affil=岡山大学 en-keyword=GASTRIC EPITHELIAL-CELLS kn-keyword=GASTRIC EPITHELIAL-CELLS en-keyword=CYTOKINE MESSENGER-RNA kn-keyword=CYTOKINE MESSENGER-RNA en-keyword=HEAT-SHOCK PROTEINS kn-keyword=HEAT-SHOCK PROTEINS en-keyword=KAPPA-B ACTIVATION kn-keyword=KAPPA-B ACTIVATION en-keyword=PROINFLAMMATORY CYTOKINES kn-keyword=PROINFLAMMATORY CYTOKINES en-keyword=ENDOTHELIAL-CELLS kn-keyword=ENDOTHELIAL-CELLS en-keyword=MONGOLIAN GERBILS kn-keyword=MONGOLIAN GERBILS en-keyword=LYMPHOID-TISSUE kn-keyword=LYMPHOID-TISSUE en-keyword=TLR 2 kn-keyword=TLR 2 en-keyword=MACROPHAGES kn-keyword=MACROPHAGES END start-ver=1.4 cd-journal=joma no-vol= cd-vols= no-issue= article-no= start-page= end-page= dt-received= dt-revised= dt-accepted= dt-pub-year=2007 dt-pub=20070323 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=変異FGFR３の恒常的リン酸化は先天性小人症の重要な因子でPLCγによるSTAT1の活性化を介して軟骨前駆細胞ATDC5のアポトーシスを誘導する kn-title=Sustained phosphorylation of mutated FGFR3 is a crucial feature of genetic dwarfism and induces apoptosis in the ATDC5 chondrogenic cell line via PLCγ-activated STAT1 en-subtitle= kn-subtitle= en-abstract= kn-abstract=The most frequent type of rhizomelic dwarfism, achondroplasia (ACH), is caused by mutations in the fibroblast growth factor receptor 3 (FGFR3) gene. Mutations in FGFR3 result in skeletal dysplasias of variable severity, including mild phenotypic effects in hypochondroplasia (HCH), severe phenotypic effects in thanatophoric dysplasia types I (TDI) and II (TDII), and severe but survivable phenotypic effects in severe achondroplasia with developmental delay and acanthosis nigricans (SADDAN). To explore the molecular mechanisms that result in the different phenotypes, we investigated the kinetics of mutated versions of FGFR3. First, we assayed the phosphorylation states of the mutated FGFR3s and found that the level of phosphorylation in TDI-FGFR3 was lower than in ACH-FGFR3, although the other mutants were phosphorylated according to phenotypic severity. Second, we analyzed the duration of the phosphorylation. TDI-FGFR3 was not highly phosphorylated under ligand-free conditions, but the peak phosphorylation levels of TDI-FGFR3 and ACH-FGFR3 were maintained for 30 min after stimulation with FGF-1. Moreover, ligand-dependent phosphorylation of TDI-FGFR3, but not ACH-FGFR3, lasted for more than 8 h after FGF-1 administration. The other mutant proteins showed sustained phosphorylation independent of ligand presence. Third, we investigated the intracellular localization of the mutant proteins. Immunofluorescence analysis showed accumulations of TDII-FGFR3, SADDAN-FGFR3, and a portion of TDI-FGFR3 in the endoplasmic reticulum (ER). Based on these data, we concluded that sustained phosphorylation of FGFR3 causes chondrodysplasia, and the phenotypic severity depends on the proportion of ER-localized mutant FGFR3. In FGFR3 signaling, the transcription factor, signal transducer and activator of transcription 1 (STAT1) inhibit proliferation and induce apoptosis of chondrocytes. Here we reveal that phospholipase C gamma (PLCgamma) mediates FGFR3-induced STAT1 activation. Both PLCgamma and STAT1 were activated by FGFR3 signaling, but a dominant-negative form of PLCgamma (DN-PLCgamma) remarkably reduced STAT1 phosphorylation. Apoptosis assays revealed that the constitutively active forms of FGFR3 (TDII-FGFR3) and STAT1 (STAT1-C) induce apoptosis of chondrogenic ATDC5 cells via caspase activity. DN-PLCgamma reduced the apoptosis of ATDC5 cells expressing TDII-FGFR3, but over-expression of both DN-PLCgamma and STAT1-C induced apoptosis. Therefore, we conclude that a PLCgamma-STAT1 pathway mediates apoptotic signaling by FGFR3. en-copyright= kn-copyright= en-aut-name=HaradaDaisuke en-aut-sei=Harada en-aut-mei=Daisuke kn-aut-name=原田大輔 kn-aut-sei=原田 kn-aut-mei=大輔 aut-affil-num=1 ORCID= affil-num=1 en-affil= kn-affil=岡山大学 en-keyword=FGFR3 kn-keyword=FGFR3 en-keyword=Skeletal dysplasia kn-keyword=Skeletal dysplasia en-keyword=Phosphorylation kn-keyword=Phosphorylation en-keyword=ER localization kn-keyword=ER localization en-keyword=STAT1 kn-keyword=STAT1 END start-ver=1.4 cd-journal=joma no-vol= cd-vols= no-issue= article-no= start-page= end-page= dt-received= dt-revised= dt-accepted= dt-pub-year=2007 dt-pub=20070323 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=虚血後線状体に出現する神経前駆細胞の起源 kn-title=Subventricular Zone-Derived Neuroblasts Migrate and Differentiate into Mature Neurons in the Post-Stroke Adult Striatum en-subtitle= kn-subtitle= en-abstract= kn-abstract=Recent studies have revealed that the adult mammalian brain has the capacity to regenerate some neurons after various insults. However, the precise mechanism of insult-induced neurogenesis has not been demonstrated. In the normal brain, GFAP-expressing cells in the subventricular zone (SVZ) of the lateral ventricles include a neurogenic cell population that gives rise to olfactory bulb neurons only. Herein, we report evidence that, after a stroke, these cells are capable of producing new neurons outside the olfactory bulbs. SVZ GFAP-expressing cells labeled by a cell-type-specific viral infection method were found to generate neuroblasts that migrated toward the injured striatum after middle cerebral artery occlusion. These neuroblasts in the striatum formed elongated chain-like cell aggregates similar to those in the normal SVZ, and these chains were observed to be closely associated with thin astrocytic processes and blood vessels. Finally, long-term tracing of the green fluorescent-labeled cells with a Cre-loxP system revealed that the SVZ-derived neuroblasts differentiated into mature neurons in the striatum, in which they expressed neuronal-specific nuclear protein and formed synapses with neighboring striatal cells. These results highlight the role of the SVZ in neuronal regeneration after a stroke and its potential as an important therapeutic target for various neurological disorders. en-copyright= kn-copyright= en-aut-name=YamashitaToru en-aut-sei=Yamashita en-aut-mei=Toru kn-aut-name=山下徹 kn-aut-sei=山下 kn-aut-mei=徹 aut-affil-num=1 ORCID= affil-num=1 en-affil= kn-affil=岡山大学 en-keyword=zone kn-keyword=zone en-keyword=cerebral ischemia kn-keyword=cerebral ischemia en-keyword=migration kn-keyword=migration en-keyword=neurogenesis kn-keyword=neurogenesis en-keyword=regeneration kn-keyword=regeneration en-keyword=striatum kn-keyword=striatum END start-ver=1.4 cd-journal=joma no-vol= cd-vols= no-issue= article-no= start-page= end-page= dt-received= dt-revised= dt-accepted= dt-pub-year=2007 dt-pub=20070323 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=ラットL５脊髄神経結紮によるフォルマリンに対する疼痛行動変化：行動学的および分子学的検討 kn-title=Altered Response to Formalin by L5 Spinal Nerve Ligation in Rats: A Behavioral and Molecular Study en-subtitle= kn-subtitle= en-abstract= kn-abstract=BACKGROUND: The status of neuropathic pain alters the responsiveness to formalin injection in rats. However, the mechanism by which this alteration occurs is unknown. METHODS: We used immunocytochemistry to examine the expression of brain-derived neurotrophic factor (BDNF) and calcitonin gene-related peptide (CGRP) in the spinal cord of rats with L5 spinal nerve ligation (SNL)-induced neuropathy, and investigated the expression of c-Fos in the spinal cord after injection of formalin in the hindpaw of rats with SNL. RESULTS: Four weeks after SNL, the withdrawal threshold was significantly lower in the SNL group than in the sham-operated (sham) group (n = 12 per group, P < 0.05). In the SNL group, expression of BDNF in the L4 (P < 0.05) and L5 (P < 0.01) superficial dorsal horn was significantly decreased compared to that in the sham group. CGRP protein in the L5 but not in the L4, dorsal horn was significantly decreased compared to that in the sham group (P < 0.01). After formalin injection, spontaneous pain responses in the SNL group were significantly decreased compared to those in the sham group (P < 0.05). Immunolabeling for c-Fos was significantly decreased in the L4 and L5 dorsal horn in the SNL group (P < 0.01). CONCLUSION: Our examination of c-Fos distribution indicates that decreased neuronal activity in the spinal cord in response to inflammatory pain may be important for altering the perception of acute pain. Decreased BDNF expression in response to SNL-induced neuropathy may be involved in this alteration. en-copyright= kn-copyright= en-aut-name=KakuRyuji en-aut-sei=Kaku en-aut-mei=Ryuji kn-aut-name=賀来隆治 kn-aut-sei=賀来 kn-aut-mei=隆治 aut-affil-num=1 ORCID= affil-num=1 en-affil= kn-affil=岡山大学 END start-ver=1.4 cd-journal=joma no-vol= cd-vols= no-issue= article-no= start-page= end-page= dt-received= dt-revised= dt-accepted= dt-pub-year=2007 dt-pub=20070323 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=Ｔ細胞性造血器腫瘍において過剰発現が認められるHelios short isoformの機能解析 kn-title=Characterization of the short isoform of Helios overexpressed in patients with T-cell malignancies en-subtitle= kn-subtitle= en-abstract= kn-abstract=In an earlier report, we demonstrated overexpression of a short isoform of Helios, Hel-5, which lacks three of four N-terminal zinc fingers, in patients with adult T-cell leukemia/lymphoma. Here, we characterized Hel-5 using immunoprecipitation, and gel shift and luciferase promoter assays, and found that Hel-5 lacks the repressor function observed with a full-length isoform of Helios. Moreover, Hel-5 associates with the full-length isoforms of the Ikaros gene family, Ikaros, Aiolos and Helios, and inhibits their DNA binding activity when present in excess, leading to dominant-negative effects on the full-length isoforms of the Ikaros gene family. Our results suggest a critical role for Helios in the mechanism of leukemogenesis. en-copyright= kn-copyright= en-aut-name=TabayashiTakayuki en-aut-sei=Tabayashi en-aut-mei=Takayuki kn-aut-name=多林孝之 kn-aut-sei=多林 kn-aut-mei=孝之 aut-affil-num=1 ORCID= affil-num=1 en-affil= kn-affil=岡山大学 en-keyword=Mutation kn-keyword=Mutation en-keyword=Carcinogenesis kn-keyword=Carcinogenesis en-keyword=Multivariate analysis kn-keyword=Multivariate analysis en-keyword=Case-control study kn-keyword=Case-control study END start-ver=1.4 cd-journal=joma no-vol= cd-vols= no-issue= article-no= start-page= end-page= dt-received= dt-revised= dt-accepted= dt-pub-year=2006 dt-pub=20060930 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=チアゾリジン誘導体は細胞周期依存性メカニズムにより糖尿病性腎症を改善する kn-title=Thiazolidinediones Ameliorate Diabetic Nephropathy via Cell Cycle-Dependent Mechanisms en-subtitle= kn-subtitle= en-abstract= kn-abstract= en-copyright= kn-copyright= en-aut-name=OkadaTatsuo en-aut-sei=Okada en-aut-mei=Tatsuo kn-aut-name=岡田達夫 kn-aut-sei=岡田 kn-aut-mei=達夫 aut-affil-num=1 ORCID= affil-num=1 en-affil= kn-affil=岡山大学 END start-ver=1.4 cd-journal=joma no-vol= cd-vols= no-issue= article-no= start-page= end-page= dt-received= dt-revised= dt-accepted= dt-pub-year=2006 dt-pub=20060324 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=イネの発芽および幼植物期におけるアルミニウム耐性機構の研究 kn-title=A study of aluminum tolerance mechanisms at germination and seedling stages in rice Oryza sativa L. en-subtitle= kn-subtitle= en-abstract= kn-abstract= en-copyright= kn-copyright= en-aut-name=KikuiSatoshi en-aut-sei=Kikui en-aut-mei=Satoshi kn-aut-name=菊井聖士 kn-aut-sei=菊井 kn-aut-mei=聖士 aut-affil-num=1 ORCID= affil-num=1 en-affil= kn-affil=岡山大学 END start-ver=1.4 cd-journal=joma no-vol= cd-vols= no-issue= article-no= start-page= end-page= dt-received= dt-revised= dt-accepted= dt-pub-year=2006 dt-pub=20060324 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=植物細胞における糖蛋白質の脱グリコシル化機構と花粉アレルゲンに結合するN-グリカンの構造特性に関する研究 kn-title=Studies on the deglycosylation mechanism of glycoproteins in plant cell and the structural features of N-glycans linked to pollen allergens en-subtitle= kn-subtitle= en-abstract= kn-abstract= en-copyright= kn-copyright= en-aut-name=MaedaMegumi en-aut-sei=Maeda en-aut-mei=Megumi kn-aut-name=前田恵 kn-aut-sei=前田 kn-aut-mei=恵 aut-affil-num=1 ORCID= affil-num=1 en-affil= kn-affil=岡山大学 END start-ver=1.4 cd-journal=joma no-vol= cd-vols= no-issue= article-no= start-page= end-page= dt-received= dt-revised= dt-accepted= dt-pub-year=2006 dt-pub=20060324 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=サルモネラ鞭毛相変異における1相フラジェリン遺伝子のFljAによる抑制機構 kn-title=Molecular mechanism of FljA-mediated repression of the phase-1 flagellin gene in flagellar phase variation of Salmonella enterica serovar Typhimurium en-subtitle= kn-subtitle= en-abstract= kn-abstract= en-copyright= kn-copyright= en-aut-name=YamamotoShoji en-aut-sei=Yamamoto en-aut-mei=Shoji kn-aut-name=山本章治 kn-aut-sei=山本 kn-aut-mei=章治 aut-affil-num=1 ORCID= affil-num=1 en-affil= kn-affil=岡山大学 END start-ver=1.4 cd-journal=joma no-vol= cd-vols= no-issue= article-no= start-page= end-page= dt-received= dt-revised= dt-accepted= dt-pub-year=2006 dt-pub=20060324 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=腸間膜動脈抵抗血管におけるヒスタミンによる血管反応の機序に関する薬理学的研究 kn-title=Pharmacological study on mechanisms underlying vascular responses to histamine in mesenteric resistance arteries. en-subtitle= kn-subtitle= en-abstract= kn-abstract= en-copyright= kn-copyright= en-aut-name= en-aut-sei= en-aut-mei= kn-aut-name=金紅花 kn-aut-sei=金 kn-aut-mei=紅花 aut-affil-num=1 ORCID= affil-num=1 en-affil= kn-affil=岡山大学 END start-ver=1.4 cd-journal=joma no-vol= cd-vols= no-issue= article-no= start-page= end-page= dt-received= dt-revised= dt-accepted= dt-pub-year=2006 dt-pub=20060324 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=小胞型グルタミン酸輸送体のトポロジーとターゲッティングに関する研究 kn-title=Topology and Targeting Mechanism of Vesicular Glutamate Transporter en-subtitle= kn-subtitle= en-abstract= kn-abstract= en-copyright= kn-copyright= en-aut-name= en-aut-sei= en-aut-mei= kn-aut-name=鄭先京 kn-aut-sei=鄭 kn-aut-mei=先京 aut-affil-num=1 ORCID= affil-num=1 en-affil= kn-affil=岡山大学 END start-ver=1.4 cd-journal=joma no-vol= cd-vols= no-issue= article-no= start-page= end-page= dt-received= dt-revised= dt-accepted= dt-pub-year=2006 dt-pub=20060324 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=２Ｈ－及び４Ｈ－アゼピンの合成，生成機構と化学的挙動に関する研究 kn-title=Efficient Synthesis, Formation Mechanism and Chemical Behavior of 2H- and 4H-Azepines en-subtitle= kn-subtitle= en-abstract= kn-abstract= en-copyright= kn-copyright= en-aut-name= en-aut-sei= en-aut-mei= kn-aut-name=CHRISTOPHERERNEST JOHN CORDONIER kn-aut-sei=CHRISTOPHER kn-aut-mei=ERNEST JOHN CORDONIER aut-affil-num=1 ORCID= affil-num=1 en-affil= kn-affil=岡山大学 END start-ver=1.4 cd-journal=joma no-vol= cd-vols= no-issue= article-no= start-page= end-page= dt-received= dt-revised= dt-accepted= dt-pub-year=2006 dt-pub=20060324 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=母子免疫寛容は制御性T細胞を介して子母間骨髄移植の成績を改善する kn-title=Fetal Tolerance to Maternal Antigens Improves the Outcome of Allogeneic Bone Marrow Transplantation by a CD4+CD25+ T cell-Dependent Mechanism en-subtitle= kn-subtitle= en-abstract= kn-abstract= en-copyright= kn-copyright= en-aut-name=MatsuokaKen-ichi en-aut-sei=Matsuoka en-aut-mei=Ken-ichi kn-aut-name=松岡賢市 kn-aut-sei=松岡 kn-aut-mei=賢市 aut-affil-num=1 ORCID= affil-num=1 en-affil= kn-affil=岡山大学 END start-ver=1.4 cd-journal=joma no-vol= cd-vols= no-issue= article-no= start-page= end-page= dt-received= dt-revised= dt-accepted= dt-pub-year=2004 dt-pub=20040325 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=モルヒネ単回投与ラットにおけるナロキソン誘発条件付け場所嫌悪行動機序に関する神経化学及び神経解剖学的研究 kn-title=Neurochemical and neuroanatomic study on the mechanism erlying naloxone-induced conditioned place aversion in rats undergoing a single morphine exposure en-subtitle= kn-subtitle= en-abstract= kn-abstract= en-copyright= kn-copyright= en-aut-name=JinChunyu en-aut-sei=Jin en-aut-mei=Chunyu kn-aut-name=金春玉 kn-aut-sei=金 kn-aut-mei=春玉 aut-affil-num=1 ORCID= affil-num=1 en-affil= kn-affil=岡山大学 END start-ver=1.4 cd-journal=joma no-vol= cd-vols= no-issue= article-no= start-page= end-page= dt-received= dt-revised= dt-accepted= dt-pub-year=2005 dt-pub=20050325 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=リンク型劣駆動機械システムの非線形制御 kn-title=Nonlinear Control of Underactuated Linked Mechanical Systems en-subtitle= kn-subtitle= en-abstract= kn-abstract= en-copyright= kn-copyright= en-aut-name=HenmiTomohiro en-aut-sei=Henmi en-aut-mei=Tomohiro kn-aut-name=逸見知弘 kn-aut-sei=逸見 kn-aut-mei=知弘 aut-affil-num=1 ORCID= affil-num=1 en-affil= kn-affil=岡山大学 END start-ver=1.4 cd-journal=joma no-vol= cd-vols= no-issue= article-no= start-page= end-page= dt-received= dt-revised= dt-accepted= dt-pub-year=2004 dt-pub=20040325 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=歯科インプラントの安定性および形状アセスメントのための機械モビリティ技法に関する研究 kn-title=Mechanical Mobility Technique for Stability and Geometry Assessment of Dental Implant en-subtitle= kn-subtitle= en-abstract= kn-abstract= en-copyright= kn-copyright= en-aut-name=WijayaSastra Kusuma en-aut-sei=Wijaya en-aut-mei=Sastra Kusuma kn-aut-name=ウィジャヤサストラ クスマ kn-aut-sei=ウィジャヤ kn-aut-mei=サストラ クスマ aut-affil-num=1 ORCID= affil-num=1 en-affil= kn-affil=岡山大学 END start-ver=1.4 cd-journal=joma no-vol= cd-vols= no-issue= article-no= start-page= end-page= dt-received= dt-revised= dt-accepted= dt-pub-year=2004 dt-pub=20040630 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=圧迫力による肘関節脱臼骨折の発生機序の力学的解析 kn-title=Biomechanical analysis of the mechanism of elbow fracture-dislocations by compression force en-subtitle= kn-subtitle= en-abstract= kn-abstract= en-copyright= kn-copyright= en-aut-name=WakeHirofumi en-aut-sei=Wake en-aut-mei=Hirofumi kn-aut-name=和氣博文 kn-aut-sei=和氣 kn-aut-mei=博文 aut-affil-num=1 ORCID= affil-num=1 en-affil= kn-affil=岡山大学 END start-ver=1.4 cd-journal=joma no-vol= cd-vols= no-issue= article-no= start-page= end-page= dt-received= dt-revised= dt-accepted= dt-pub-year=2005 dt-pub=20050325 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=CHO細胞における六価クロム誘導のアポトーシス機構にはセラミドが関与する kn-title=Involvement of Ceramide in the Mechanism of Cr(VI)-induced Apoptosis of CHO Cells en-subtitle= kn-subtitle= en-abstract= kn-abstract= en-copyright= kn-copyright= en-aut-name=MuranakaShikibu en-aut-sei=Muranaka en-aut-mei=Shikibu kn-aut-name=村中式部 kn-aut-sei=村中 kn-aut-mei=式部 aut-affil-num=1 ORCID= affil-num=1 en-affil= kn-affil=岡山大学 END start-ver=1.4 cd-journal=joma no-vol= cd-vols= no-issue= article-no= start-page= end-page= dt-received= dt-revised= dt-accepted= dt-pub-year=2005 dt-pub=20050630 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=15-デオキシ-12,14-プロスタグランジンJ2による軟骨肉腫細胞の成長抑制機序におけるBax/Bcl-xLとp21発現変化 kn-title=Suppression of chondrosarcoma cells by 15-deoxy-Delta 12,14-prostaglandin J2 is associated with altered expression of Bax/Bcl-xL and p21 en-subtitle= kn-subtitle= en-abstract= kn-abstract=We previously reported that 15-deoxy-Delta(12,14)-prostaglandin J(2) (15d-PGJ(2)), the most potent agonist for peroxisome proliferator-activated receptor gamma (PPAR gamma), induces apoptosis of human chondrosarcoma cell line OUMS-27. The current study aimed to explore the mechanism of 15d-PGJ(2)-induced apoptosis and inhibition of cell proliferation in OUMS-27 cells. The preliminary results of cDNA microarray analysis showed the down-regulation of anti-apoptotic Bcl-xL and up-regulation of pro-apoptotic Bax in the process of 15d-PGJ(2)-induced apoptosis. These changes were further confirmed at mRNA and protein levels by RT-PCR and Western blot analysis, respectively. Among cyclin-dependent kinase inhibitors, p21 was induced and up-regulated by 15d-PGJ(2), but p16 and p27 were not changed, suggesting that the involvement of p21 in inhibition of cell proliferation. Activation of caspase-3 by 15d-PGJ(2) was partly, but not completely, blocked by PPAR gamma antagonist (GW9662) suggesting the 15d-PGJ(2) exerted its effect by PPAR gamma-dependent and -independent pathways. Interestingly, immunohistochemical study on human chondrosarcoma samples revealed that Bcl-xL is frequently expressed by tumor cells. The results of the current study suggest that the potential ability of 15d-PGJ(2) in regulation of cell cycle and inhibition of Bcl-xL expression might be beneficial in the development of novel pharmacological agents for chondrosarcoma. en-copyright= kn-copyright= en-aut-name=ShenZheng-Nan en-aut-sei=Shen en-aut-mei=Zheng-Nan kn-aut-name=申正男 kn-aut-sei=申 kn-aut-mei=正男 aut-affil-num=1 ORCID= affil-num=1 en-affil= kn-affil=岡山大学 en-keyword=Chondrosarcoma kn-keyword=Chondrosarcoma en-keyword=Apoptosis kn-keyword=Apoptosis en-keyword=PPARγ kn-keyword=PPARγ en-keyword=15d-PGJ2 kn-keyword=15d-PGJ2 en-keyword=Bcl-xL kn-keyword=Bcl-xL en-keyword=p21 kn-keyword=p21 END start-ver=1.4 cd-journal=joma no-vol= cd-vols= no-issue= article-no= start-page= end-page= dt-received= dt-revised= dt-accepted= dt-pub-year=2004 dt-pub=20040930 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=Osteoclastogenesis Inhibitory Factor/Osteoprotegerinは力学的負荷軽減による骨減少を抑制した kn-title=Osteoclastogenesis Inhibitory Factor/Osteoprotegerin Reduced Bone Loss Induced by Mechanical Unloading en-subtitle= kn-subtitle= en-abstract= kn-abstract= en-copyright= kn-copyright= en-aut-name=IchinoseYojiro en-aut-sei=Ichinose en-aut-mei=Yojiro kn-aut-name=一ノ瀨洋次郎 kn-aut-sei=一ノ瀨 kn-aut-mei=洋次郎 aut-affil-num=1 ORCID= affil-num=1 en-affil= kn-affil=岡山大学 END start-ver=1.4 cd-journal=joma no-vol= cd-vols= no-issue= article-no= start-page= end-page= dt-received= dt-revised= dt-accepted= dt-pub-year=1999 dt-pub=19990325 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=異方的ならびに量子極限の超伝導体における渦構造 kn-title=Vortex structure in anisotropic and quantum-limit superconductors en-subtitle= kn-subtitle= en-abstract= kn-abstract=Electronic structure of a single vortex (or vortex core structure) in type-II superconductors is theoretically discussed in the present thesis. Low-lying excited states in the superconductors due to the vortex, i.e., "vortex bound states," are examined in detail on the basis of numerical calculations. Two points are focused on: the effect of superconducting gap anisotropy on a vortex (Chapter 2) and the property of a vortex in quantum-limit situation (Chapter 3). The anisotropy of a superconducting energy gap has substantial effects on the structure of the vortex bound states. The local density of states around a vortex is calculated in a clean superconductor with the gap anisotropy within the framework of the quasiclassical theory of superconductivity. A characteristic structure of the local density of states, observed experimentally in the layered hexagonal superconductor 2H-NbSe(2) by scanning tunneling microscopy (STM), is well reproduced by assuming an anisotropic s-wave gap. The local density of states (or the bound states) around a vortex in superconductors with gap anisotropy is interpreted in terms of quasiparticle trajectories to facilitate an understanding of the rich electronic structure observed in STM experiments. This reveals not only a rich internal electronic structure associated with a vortex core, but also unique ability of the STM spectroscopy. The quantum limit means that the superconducting coherence length is small in the limit, i.e., it is comparable to the atomic length order. Focusing on quantum-limit behavior, fundamental structure of a vortex is studied by self-consistently solving the Bogoliubov-de Gennes equation. The discreteness of the energy levels of the vortex bound states is crucial for the vortex structure in the quantum limit. The following are revealed by the study of the quantum limit. The vortex core radius shrinks monotonically up to an atomic-scale length on lowering the temperature T, and the shrinkage stops to saturate at a lower T. The pair potential, supercurrent, and local density of states around the vortex exhibit Friedel-like oscillations. The local density of states inside a vortex core generally has particle-hole asymmetry induced by the existence of the vortex itself. Some essential properties of general vortices which are concealed within the conventional non-quantum-limit analysis can be extracted by the quantum-limit analysis. On the basis of the inherent particle-hole asymmetry inside vortex cores, it is discussed in this thesis that electric charging of a vortex core is originated from the Friedel oscillation of the Bogoliubov wave functions around the vortex (Chapter 4) . This mechanism of the vortex core charging is independent of the slope in the normal-state density of states at the Fermi level. The temperature dependence of the vortex core charge is also presented. It is expected that by using STM, information on the vortex core charging is extracted through a relation between the vortex core charge and the vortex bound states. en-copyright= kn-copyright= en-aut-name=HayashiNobuhiko en-aut-sei=Hayashi en-aut-mei=Nobuhiko kn-aut-name=林伸彦 kn-aut-sei=林 kn-aut-mei=伸彦 aut-affil-num=1 ORCID= affil-num=1 en-affil= kn-affil=岡山大学 END start-ver=1.4 cd-journal=joma no-vol= cd-vols= no-issue= article-no= start-page= end-page= dt-received= dt-revised= dt-accepted= dt-pub-year=1998 dt-pub=19980930 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=光化学系II D1 蛋白質前駆体カルボキシル末端プロセシング酵素の基質認識機構 kn-title=Mechanism of substrate-recognition- by a protease in the carboxy1- terminal processing of precursor D1 protein in photosystem II. en-subtitle= kn-subtitle= en-abstract= kn-abstract= en-copyright= kn-copyright= en-aut-name= en-aut-sei= en-aut-mei= kn-aut-name=田口富美子 kn-aut-sei=田口 kn-aut-mei=富美子 aut-affil-num=1 ORCID= affil-num=1 en-affil= kn-affil=岡山大学 END start-ver=1.4 cd-journal=joma no-vol= cd-vols= no-issue= article-no= start-page= end-page= dt-received= dt-revised= dt-accepted= dt-pub-year=1995 dt-pub=19950325 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=コオロギ生殖器官の力学活動における神経分泌細胞の機能的役割 kn-title=Functional role of neurosecretory cells in the mechanical activity of the reproductive organs in the crlcket (Grllus bimaculatus) en-subtitle= kn-subtitle= en-abstract= kn-abstract= en-copyright= kn-copyright= en-aut-name= en-aut-sei= en-aut-mei= kn-aut-name=陳斌 kn-aut-sei=陳 kn-aut-mei=斌 aut-affil-num=1 ORCID= affil-num=1 en-affil= kn-affil=岡山大学 END start-ver=1.4 cd-journal=joma no-vol= cd-vols= no-issue= article-no= start-page= end-page= dt-received= dt-revised= dt-accepted= dt-pub-year=1996 dt-pub=19960325 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=コオロギ死にまね行動の神経機構 kn-title=Neural mechanism of thanatosis in the cricket en-subtitle= kn-subtitle= en-abstract= kn-abstract= en-copyright= 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dt-pub-year=1995 dt-pub=19950325 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=酸素関連ラジカル種による培養心筋細胞障害:障害のメカニズムならびに細胞内防御機構の解明 kn-title=Oxygen derived free radical-induced cultured cardiac myocyte damages: evaluation of the mechanisms of the injuries and the cellular defense system en-subtitle= kn-subtitle= en-abstract= kn-abstract= en-copyright= kn-copyright= en-aut-name= en-aut-sei= en-aut-mei= kn-aut-name=西谷友重 kn-aut-sei=西谷 kn-aut-mei=友重 aut-affil-num=1 ORCID= affil-num=1 en-affil= kn-affil=岡山大学 END start-ver=1.4 cd-journal=joma no-vol= cd-vols= no-issue= article-no= start-page= end-page= dt-received= dt-revised= dt-accepted= dt-pub-year=2002 dt-pub=20020325 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=中温性混合栄養鉄酸化細菌OKM-9株における混合栄養的代謝機構解明に関する研究 kn-title=Studies on the Mechanism of Mixotrophic Metabolism in a Mesophilic, Mixotrophic Iron-oxidizing Bacterium Strain OKM-9 en-subtitle= kn-subtitle= en-abstract= kn-abstract= en-copyright= 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dt-pub=20000325 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=高等植物におけるムシラーゲと有機酸によるアルミニウム無毒化機構 kn-title=Aluminum Detoxification Mechanism by Organic Acids and Mucilage in Higher Plants en-subtitle= kn-subtitle= en-abstract= kn-abstract= en-copyright= kn-copyright= en-aut-name= en-aut-sei= en-aut-mei= kn-aut-name=黎暁峰 kn-aut-sei=黎 kn-aut-mei=暁峰 aut-affil-num=1 ORCID= affil-num=1 en-affil= kn-affil=岡山大学 END start-ver=1.4 cd-journal=joma no-vol= cd-vols= no-issue= article-no= start-page= end-page= dt-received= dt-revised= dt-accepted= dt-pub-year=1999 dt-pub=19990325 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=小麦におけるアルミニウム誘導鉄クロロシスの機構について kn-title=Mechanisms of Aluminum-Induced Iron Chlorosis in Wheat (Triticum aestivum ) en-subtitle= kn-subtitle= en-abstract= kn-abstract= en-copyright= kn-copyright= en-aut-name= en-aut-sei= en-aut-mei= kn-aut-name=張藝潔 kn-aut-sei=張 kn-aut-mei=藝潔 aut-affil-num=1 ORCID= affil-num=1 en-affil= kn-affil=岡山大学 END 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kn-aut-mei=Rafiquzzaman aut-affil-num=1 ORCID= affil-num=1 en-affil= kn-affil=岡山大学 END start-ver=1.4 cd-journal=joma no-vol= cd-vols= no-issue= article-no= start-page= end-page= dt-received= dt-revised= dt-accepted= dt-pub-year=2001 dt-pub=20010325 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=植物におけるアルミニウム毒性機構に関する研究 kn-title=On the Mechanism of Aluminum Toxicity in Plants en-subtitle= kn-subtitle= en-abstract= kn-abstract= en-copyright= kn-copyright= en-aut-name= en-aut-sei= en-aut-mei= kn-aut-name=MayandiSivaguru kn-aut-sei=Mayandi kn-aut-mei=Sivaguru aut-affil-num=1 ORCID= affil-num=1 en-affil= kn-affil=岡山大学 END start-ver=1.4 cd-journal=joma no-vol= cd-vols= no-issue= article-no= start-page= end-page= dt-received= dt-revised= dt-accepted= dt-pub-year=2000 dt-pub=20000325 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=塩水条件下における小麦品種の諸特性ならびに耐塩性機構に及ぼす無機イオン分布の役割 kn-title=Performance of wheat varieties under salt-affected conditions and role of mineral ions distribution in salt tolerance mechanisms en-subtitle= kn-subtitle= en-abstract= kn-abstract= en-copyright= kn-copyright= en-aut-name= en-aut-sei= en-aut-mei= kn-aut-name=MaqsoodAhamed Kamboh kn-aut-sei=Maqsood kn-aut-mei=Ahamed Kamboh aut-affil-num=1 ORCID= affil-num=1 en-affil= kn-affil=岡山大学 END start-ver=1.4 cd-journal=joma no-vol= cd-vols= no-issue= article-no= start-page= end-page= dt-received= dt-revised= dt-accepted= dt-pub-year=1999 dt-pub=19990930 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=イヌ左心室において温度上昇により収縮性の酸素コストは増加するが機械的エネルギーの酸素コストは変化しない kn-title=O'2 cost of contractility but not of mechanical energy increases with temperature in canine left ventricle en-subtitle= kn-subtitle= en-abstract= kn-abstract= en-copyright= kn-copyright= en-aut-name= en-aut-sei= en-aut-mei= kn-aut-name=實金健 kn-aut-sei=實金 kn-aut-mei=健 aut-affil-num=1 ORCID= affil-num=1 en-affil= kn-affil=岡山大学 END start-ver=1.4 cd-journal=joma no-vol= cd-vols= no-issue= article-no= start-page= end-page= dt-received= dt-revised= dt-accepted= dt-pub-year=1999 dt-pub=19990331 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=期外収縮後収縮性回復と収縮性増強による心房細動中の左室収縮性の予測 kn-title=Ventricular contractility in atrial fibrillation is predictable by mechanical restitution and potentiation en-subtitle= kn-subtitle= en-abstract= kn-abstract= en-copyright= kn-copyright= en-aut-name= en-aut-sei= en-aut-mei= kn-aut-name=鈴木俊輔 kn-aut-sei=鈴木 kn-aut-mei=俊輔 aut-affil-num=1 ORCID= affil-num=1 en-affil= kn-affil=岡山大学 END start-ver=1.4 cd-journal=joma no-vol= cd-vols= no-issue= article-no= start-page= end-page= dt-received= dt-revised= dt-accepted= dt-pub-year=1993 dt-pub=19930930 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=種々の耐性機構を示すアドリアマイシン耐性ヒト肺小細胞癌株の樹立 kn-title=Establishment of an Adriamycin-Resistant Subline of Human Small Cell Lung Cancer Showing Multifactorial Mechanisms of Resistance en-subtitle= kn-subtitle= en-abstract= kn-abstract= en-copyright= kn-copyright= en-aut-name=KiuraKatsuyuki en-aut-sei=Kiura en-aut-mei=Katsuyuki kn-aut-name=木浦勝行 kn-aut-sei=木浦 kn-aut-mei=勝行 aut-affil-num=1 ORCID= affil-num=1 en-affil= kn-affil=岡山大学 END start-ver=1.4 cd-journal=joma no-vol= cd-vols= no-issue= article-no= start-page= end-page= dt-received= dt-revised= dt-accepted= dt-pub-year=2000 dt-pub=20000630 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=期外収縮後収縮性増強における交互脈型減衰の成因の一部を心筋の機械的復帰曲線と増強曲線により説明する:シュミレーション kn-title=Myocardial mechanical restitution and potentiation partly underlie alternans decay of postextrasystolic potentiation: simulation en-subtitle= kn-subtitle= en-abstract= kn-abstract= en-copyright= kn-copyright= en-aut-name= en-aut-sei= en-aut-mei= kn-aut-name=毛利聡 kn-aut-sei=毛利 kn-aut-mei=聡 aut-affil-num=1 ORCID= affil-num=1 en-affil= kn-affil=岡山大学 END start-ver=1.4 cd-journal=joma no-vol= cd-vols= no-issue= article-no= start-page= end-page= dt-received= dt-revised= dt-accepted= dt-pub-year=1991 dt-pub=19910331 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=ストレスによるACTH及びカテコールアミン分泌における中枢性アンジオテンシン系並びに中枢性α-1アドレナリン機構の関与) 第1編振盪ストレスによるACTH及びカテコールアミン分泌における中枢性アンジオテンシン系の関与) 第2編振盪ストレスによるACTH及びノルアドレナリン分泌における中枢性α-1アドレナリン機構の関与 kn-title=Role　of　central　angiotensinergic　and　alpha-1　adrenergic　mechanism　in　stress-induced　ACTH　and　catecholamine　secretion　　第1編　Role　of　central　angiotensinergic　mechanism　in　shaking　stress-induced　ACTH　　and　catecholamine　secretion　　第2編　Role　of　central　alpha-1　adrenergic　mechanism　in　shaking　stress-induced　ACTH　and　noradrenaline　secretion en-subtitle= kn-subtitle= en-abstract= kn-abstract= en-copyright= kn-copyright= en-aut-name= en-aut-sei= en-aut-mei= kn-aut-name=平沢龍登 kn-aut-sei=平沢 kn-aut-mei=龍登 aut-affil-num=1 ORCID= affil-num=1 en-affil= kn-affil=岡山大学 END start-ver=1.4 cd-journal=joma no-vol= cd-vols= no-issue= article-no= start-page= end-page= dt-received= dt-revised= dt-accepted= dt-pub-year=1990 dt-pub=19900930 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=ハインツ小体形成による赤血球変形能低下の機序に関する研究 kn-title=On the Mechanism of Loss of Deformability in Human Erythrocytes due to Heinz Body Formation : A Flow EPR Study en-subtitle= kn-subtitle= en-abstract= kn-abstract= en-copyright= kn-copyright= en-aut-name= en-aut-sei= en-aut-mei= kn-aut-name=福島泰法 kn-aut-sei=福島 kn-aut-mei=泰法 aut-affil-num=1 ORCID= affil-num=1 en-affil= kn-affil=岡山大学 END start-ver=1.4 cd-journal=joma no-vol= cd-vols= no-issue= article-no= start-page= end-page= dt-received= dt-revised= dt-accepted= dt-pub-year=1987 dt-pub=19870630 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=α-グアニジノグルタル酸のけいれん誘発作用と,α-グアニジノグルタル酸誘発けいれん発現機構における5-ハイドロキシトリプタミンの関与 kn-title=Convulsive Activity of α-Guanidinoglutaric Acid and the Possible Involvement of 5-Hydroxytryptamine in the α-Guanidinoglutaric Acid-Induced Seizure Mechanism en-subtitle= kn-subtitle= en-abstract= kn-abstract= en-copyright= kn-copyright= en-aut-name= en-aut-sei= en-aut-mei= kn-aut-name=白神浩史 kn-aut-sei=白神 kn-aut-mei=浩史 aut-affil-num=1 ORCID= affil-num=1 en-affil= kn-affil=岡山大学 END start-ver=1.4 cd-journal=joma no-vol= cd-vols= no-issue= article-no= start-page= end-page= dt-received= dt-revised= dt-accepted= dt-pub-year=1974 dt-pub=19740630 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=内圧上昇によって誘起される蠕動波における縦走筋の電気的活動と機械的活動について kn-title=Electrical and Mechanical Activities of the Lorgitudina Muscle in the Peristaltic Wave Elicited by the Intraluminal Pressure Raising en-subtitle= kn-subtitle= en-abstract= kn-abstract= en-copyright= kn-copyright= en-aut-name= en-aut-sei= en-aut-mei= kn-aut-name=土屋勝彦 kn-aut-sei=土屋 kn-aut-mei=勝彦 aut-affil-num=1 ORCID= affil-num=1 en-affil= kn-affil=岡山大学 END start-ver=1.4 cd-journal=joma no-vol= cd-vols= no-issue= article-no= start-page= end-page= dt-received= dt-revised= dt-accepted= dt-pub-year=1982 dt-pub=19820331 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=肝髄外造血成立機転の研究(成熟マウス肝における髄外造血の観察) kn-title=A Study on the mechanism of development of extramedullary hemopoiesis ; an observation on adult mouse liver en-subtitle= kn-subtitle= en-abstract= kn-abstract= en-copyright= kn-copyright= en-aut-name= en-aut-sei= en-aut-mei= kn-aut-name=切塚敬治 kn-aut-sei=切塚 kn-aut-mei=敬治 aut-affil-num=1 ORCID= affil-num=1 en-affil= kn-affil=岡山大学 END start-ver=1.4 cd-journal=joma no-vol= cd-vols= no-issue= article-no= start-page= end-page= dt-received= dt-revised= dt-accepted= dt-pub-year=1972 dt-pub=19720331 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=細胞認識の認識機構:コニカナバリンAによる自己非自己赤球膜及び表面の変化と単球の貪食性について kn-title=Studies on cellular recognition mechanism : Effect of conncanavalin A on the phogocytosis of homologous red cells by peritoneal macrophage en-subtitle= kn-subtitle= en-abstract= kn-abstract= en-copyright= kn-copyright= en-aut-name= en-aut-sei= en-aut-mei= kn-aut-name=石川義磨 kn-aut-sei=石川 kn-aut-mei=義磨 aut-affil-num=1 ORCID= affil-num=1 en-affil= kn-affil=岡山大学 END start-ver=1.4 cd-journal=joma no-vol= cd-vols= no-issue= article-no= start-page= end-page= dt-received= dt-revised= dt-accepted= dt-pub-year=2000 dt-pub=20000325 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=正常型p53発現アデノウイルスベクターによる腫瘍血管新生抑制効果:バイスタンダー効果の機序について kn-title=Recombinant Adenovirus Expressing Wild-Type p53 Is Antiangiogenic:A Proposed Mechanism for Bystander Effect en-subtitle= kn-subtitle= en-abstract= kn-abstract= en-copyright= kn-copyright= en-aut-name= en-aut-sei= en-aut-mei= kn-aut-name=西﨑正彦 kn-aut-sei=西﨑 kn-aut-mei=正彦 aut-affil-num=1 ORCID= affil-num=1 en-affil= kn-affil=岡山大学 END start-ver=1.4 cd-journal=joma no-vol= cd-vols= no-issue= article-no= start-page= end-page= dt-received= dt-revised= dt-accepted= dt-pub-year=1986 dt-pub=19861231 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=免疫系よりみた肝再生と腫瘍免疫の増強効果に関する研究) 第1編肝部分切除後に移植されたマウス肝癌の完全退縮とその免疫機構) 第2編担癌マウスリンパ球のノイラミニダーゼ処理によるNK活性の増強 kn-title=Studies　of　Liver　Regeneration　on　the　Immune　System　and　Effect　of　Augmented　Tumor　Immunity　　第1編　Complete　Regression　of　Mouse　Hepatoma　Transplanted　after　Partial　Hepatectomy　and　the　Immmological　Mechanism　of　Such　Regression　　第2編　Augmentation　of　Natural　Killer　Activity　by　Neuraminidase　Treatment　of　Lymphocytes　from　Tumor-Bearing　Mice en-subtitle= kn-subtitle= en-abstract= kn-abstract= en-copyright= kn-copyright= en-aut-name= en-aut-sei= en-aut-mei= kn-aut-name=小野稔 kn-aut-sei=小野 kn-aut-mei=稔 aut-affil-num=1 ORCID= affil-num=1 en-affil= kn-affil=岡山大学 END start-ver=1.4 cd-journal=joma no-vol= cd-vols= no-issue= article-no= start-page= end-page= dt-received= dt-revised= dt-accepted= dt-pub-year=1985 dt-pub=19850930 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=マクロフｧージの負荷電異物貪食機構に関する研究 kn-title=Endocytic Mechanism of Macrophages to Anionic Foreign Substances en-subtitle= kn-subtitle= en-abstract= kn-abstract= en-copyright= kn-copyright= en-aut-name= en-aut-sei= en-aut-mei= kn-aut-name=小野俊郎 kn-aut-sei=小野 kn-aut-mei=俊郎 aut-affil-num=1 ORCID= affil-num=1 en-affil= kn-affil=岡山大学 END start-ver=1.4 cd-journal=joma no-vol= cd-vols= no-issue= article-no= start-page= end-page= dt-received= dt-revised= dt-accepted= dt-pub-year=1972 dt-pub=19721231 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=In vitroにおける感作局所リノパ節細胞の標的細胞に対する作用機作について kn-title=Action mechanism in vitro of sensitized regional lymph node cells on target cell en-subtitle= kn-subtitle= en-abstract= kn-abstract= en-copyright= kn-copyright= en-aut-name= en-aut-sei= en-aut-mei= kn-aut-name=小長英二 kn-aut-sei=小長 kn-aut-mei=英二 aut-affil-num=1 ORCID= affil-num=1 en-affil= kn-affil=岡山大学 END start-ver=1.4 cd-journal=joma no-vol= cd-vols= no-issue= article-no= start-page= end-page= dt-received= dt-revised= dt-accepted= dt-pub-year=1994 dt-pub=19940930 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=The mechanism of human basophil activation through the low affinity IgG receptor (Fc γ RⅡ) : Analysis of calcium mobilization using a new flow cytometric method kn-title=低新和性IgGレセプター(FcγRⅡ)を介するヒト好塩基球の活性化機序に関する研究―フローサイトメーターによるカルシウム動態の解析― en-subtitle= kn-subtitle= en-abstract= kn-abstract= en-copyright= kn-copyright= en-aut-name=SuwakiToshimitsu en-aut-sei=Suwaki en-aut-mei=Toshimitsu kn-aut-name=洲脇俊充 kn-aut-sei=洲脇 kn-aut-mei=俊充 aut-affil-num=1 ORCID= affil-num=1 en-affil= kn-affil=岡山大学 END start-ver=1.4 cd-journal=joma no-vol= cd-vols= no-issue= article-no= start-page= end-page= dt-received= dt-revised= dt-accepted= dt-pub-year=1988 dt-pub=19880331 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=アンモニア解毒機構における尿素,グルタミン合成系の動的関連:劇症肝炎ラットでの15NH4Clを用いた追跡実験 kn-title=Dynamic Relationship Between Urea And Glutamine Synthesis in the Mechanism of Ammonia Detoxication : A Tracer Study Using 15NH4Cl in Fulminant Hepatic Failure Rats en-subtitle= kn-subtitle= en-abstract= kn-abstract= en-copyright= kn-copyright= en-aut-name= en-aut-sei= en-aut-mei= kn-aut-name=守本洋一 kn-aut-sei=守本 kn-aut-mei=洋一 aut-affil-num=1 ORCID= affil-num=1 en-affil= kn-affil=岡山大学 END start-ver=1.4 cd-journal=joma no-vol= cd-vols= no-issue= article-no= start-page= end-page= dt-received= dt-revised= dt-accepted= dt-pub-year=1991 dt-pub=19910328 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=天然型ヒト腫瘍壊死因子と天然型ヒトインターフｪロン-αの併用による抗腫瘍効果の細胞周期からみたメカニズムの検討 kn-title=Mechanism of the Combined Antitumor Effect of Natural Human Tumor Necrosis Factor-α and Natural Human Interferon-α on Cell Cycle Progression en-subtitle= kn-subtitle= en-abstract= kn-abstract= en-copyright= kn-copyright= en-aut-name= en-aut-sei= en-aut-mei= kn-aut-name=室雅彦 kn-aut-sei=室 kn-aut-mei=雅彦 aut-affil-num=1 ORCID= affil-num=1 en-affil= kn-affil=岡山大学 END start-ver=1.4 cd-journal=joma no-vol= cd-vols= no-issue= article-no= start-page= end-page= dt-received= dt-revised= dt-accepted= dt-pub-year=1992 dt-pub=19920331 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=肺移植後の呼吸不全に対する Veno-venous ECMO の実験的研究 kn-title=Experimental Study on Veno-venous Extracorporeal Membrane Oxygenation for Respiratory Failure after Lung Transplantation en-subtitle= kn-subtitle= en-abstract= kn-abstract=Extracorporeal Membrane Oxygenation (ECMO) has been adopted as a means of strong respiratory support. In lung transplantation, reimplantation response is still a serious problem. It causes severe respiratory failure which is refractory to mechanical ventilation in some cases. The purpose of this study was to evaluate the effects of veno-venous ECMO after lung transplantation using a canine autotransplantation model. The autotransplantation model was created by keeping the left lung in a warm ischemic state for 2 h. After reperfusion, the right pulmonary artery was ligated. The following two groups were studied: Group 1, Control group, (no ECMO group) (n = 6). After reperfusion, both lungs were ventilated without ECMO. Group 2, ECMO group (n = 7). After reperfusion, veno-venous ECMO support was introduced with reduction of mechanical ventilation. In the no ECMO group, four of the animals died within 210 min after reperfusion. In the ECMO group, two of the animals died of severe pulmonary edema. Data of blood gas analyses (PaO2, PaCO2, and SvO2) after reperfusion were significantly better in the ECMO group, whereas there were no significant differences in both shunt fraction and pulmonary vascular resistance index. In this model with severe pulmonary edema induced by warm ischemia, veno-venous ECMO contributed to the improvement of hypoxemia and hypercapnia, but did not improve pulmonary hemodynamics. en-copyright= kn-copyright= en-aut-name=IchibaShingo en-aut-sei=Ichiba en-aut-mei=Shingo kn-aut-name=市場晋吾 kn-aut-sei=市場 kn-aut-mei=晋吾 aut-affil-num=1 ORCID= affil-num=1 en-affil= kn-affil=岡山大学 en-keyword=extracorporeal membrance oxygenation(ECMO) kn-keyword=extracorporeal membrance oxygenation(ECMO) en-keyword=warm ischemia, reimplantation kn-keyword=warm ischemia, reimplantation en-keyword=lung transplantation kn-keyword=lung transplantation en-keyword=pulmonary edema kn-keyword=pulmonary edema en-keyword=veno-venous ECMO kn-keyword=veno-venous ECMO END start-ver=1.4 cd-journal=joma no-vol= cd-vols= no-issue= article-no= start-page= end-page= dt-received= dt-revised= dt-accepted= dt-pub-year=2002 dt-pub=20020325 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=牛網膜色素上皮細胞のTIMP-1産生は周期的伸展に反応して増加する kn-title=TIMP-1 Production by Bovine Retinal Pigment Epithelial Cells Increases in Response to Cyclic Mechanical Stretch en-subtitle= kn-subtitle= en-abstract= kn-abstract= en-copyright= kn-copyright= en-aut-name= en-aut-sei= en-aut-mei= kn-aut-name=山口樹一郎 kn-aut-sei=山口 kn-aut-mei=樹一郎 aut-affil-num=1 ORCID= affil-num=1 en-affil= kn-affil=岡山大学 END start-ver=1.4 cd-journal=joma no-vol= cd-vols= no-issue= article-no= start-page= end-page= dt-received= dt-revised= dt-accepted= dt-pub-year=2000 dt-pub=20001231 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=周期的伸展力による人強膜線維芽細胞のTIMP-1産生減少 kn-title=TIMP-1 production by human scleral fibroblasts decreases in response to cyclic mechanical stretching en-subtitle= kn-subtitle= en-abstract= kn-abstract= en-copyright= kn-copyright= en-aut-name= en-aut-sei= en-aut-mei= kn-aut-name=山岡昭宏 kn-aut-sei=山岡 kn-aut-mei=昭宏 aut-affil-num=1 ORCID= affil-num=1 en-affil= kn-affil=岡山大学 END start-ver=1.4 cd-journal=joma no-vol= cd-vols= no-issue= article-no= start-page= end-page= dt-received= dt-revised= dt-accepted= dt-pub-year=1979 dt-pub=19790331 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=肝疾患における肝酵素の遊出機序 kn-title=The mechanism of the release of hepatic enzymes in various liver diseases. en-subtitle= kn-subtitle= en-abstract= kn-abstract= en-copyright= kn-copyright= en-aut-name= en-aut-sei= en-aut-mei= kn-aut-name=三宅周 kn-aut-sei=三宅 kn-aut-mei=周 aut-affil-num=1 ORCID= affil-num=1 en-affil= kn-affil=岡山大学 END start-ver=1.4 cd-journal=joma no-vol= cd-vols= no-issue= article-no= start-page= end-page= dt-received= dt-revised= dt-accepted= dt-pub-year=1985 dt-pub=19851231 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=自己免疫性溶血性貧血における溶血機序に関する研究 第1編: 感作赤血球をターゲットにしたADCC:リンパ球と単球のADCC活性の比較 第2編: 自己免疫性溶血性貧血における網内系機能:末梢血単球の活性化機序に関する研究 kn-title=STUDIES ON　THE　MECHANISM　OF　RED　CELL　DESTRUCTION　IN　AUTOIMMUNE　HEMOLYTIC　ANEMIA　(AIHA)　　第1編：ANTIBODY-DEPENDENT　CELLMEDIATED　CYTOTOXICITY　(ADCC)　TOWARD　HUMAN　O+　RED　CELLS　COATED　WITH　ANTI-D　ANTIBODY:　COMPARISON　BETWEEN　LYMPHOCYTE　AND　MONOCYTE　ADCC　ACTIVITY　　第2編：　RETICULOENDOTHELIAL　CELL　FUNCTION　IN　AUTOIMMUNE　HEMOLYTIC　ANEMIA　(AIHA)　：　STUDIES　ON　THE　MECHANISM　OF　PERIPHERAL　MONO-CYTE　ACTIVATION en-subtitle= kn-subtitle= en-abstract= kn-abstract= en-copyright= kn-copyright= en-aut-name= en-aut-sei= en-aut-mei= kn-aut-name=砂田光俊 kn-aut-sei=砂田 kn-aut-mei=光俊 aut-affil-num=1 ORCID= affil-num=1 en-affil= kn-affil=岡山大学 END start-ver=1.4 cd-journal=joma no-vol= cd-vols= no-issue= article-no= start-page= end-page= dt-received= dt-revised= dt-accepted= dt-pub-year=2001 dt-pub=20011231 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=橈骨遠位端骨折に対する髄内鋼線固定法と経骨片Kirschner鋼線固定法の力学的強度 kn-title=MECHANICAL STRENGTH OF INTRAMEDULLARY PINNING AND TRANSFRAGMENTAL KIRSCHNER WIRE FIXATION FOR COLLES' FRACTURES en-subtitle= kn-subtitle= en-abstract= kn-abstract= en-copyright= kn-copyright= en-aut-name= en-aut-sei= en-aut-mei= kn-aut-name=佐伯祐司 kn-aut-sei=佐伯 kn-aut-mei=祐司 aut-affil-num=1 ORCID= affil-num=1 en-affil= kn-affil=岡山大学 END start-ver=1.4 cd-journal=joma no-vol= cd-vols= no-issue= article-no= start-page= end-page= dt-received= dt-revised= dt-accepted= dt-pub-year=2000 dt-pub=20000325 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=ヒト線維柱帯細胞における機械的伸展力特異的遺伝子(オキュロメジン kn-title=A Novel Gene(Oculomedin)Induced by Mechanical Stretching in Human Trabecular Cells of the Eye en-subtitle= kn-subtitle= en-abstract= kn-abstract= en-copyright= kn-copyright= en-aut-name= en-aut-sei= en-aut-mei= kn-aut-name=佐藤由希子 kn-aut-sei=佐藤 kn-aut-mei=由希子 aut-affil-num=1 ORCID= affil-num=1 en-affil= kn-affil=岡山大学 END start-ver=1.4 cd-journal=joma no-vol= cd-vols= no-issue= article-no= start-page= end-page= dt-received= dt-revised= dt-accepted= dt-pub-year=1975 dt-pub=19750331 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=分離したラツト肥満細胞からのα-キモトリプシンによるヒスタミン遊離の機構 kn-title=Mechanism of histamine release by alpha-cymotrypsin from isolated rat mast cells en-subtitle= kn-subtitle= en-abstract= kn-abstract= en-copyright= kn-copyright= en-aut-name= en-aut-sei= en-aut-mei= kn-aut-name=佐々木順造 kn-aut-sei=佐々木 kn-aut-mei=順造 aut-affil-num=1 ORCID= affil-num=1 en-affil= kn-affil=岡山大学 END start-ver=1.4 cd-journal=joma no-vol= cd-vols= no-issue= article-no= start-page= end-page= dt-received= dt-revised= dt-accepted= dt-pub-year=1988 dt-pub=19880328 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=フットショックによるマウス脳内ヒスタミン代謝回転の亢進におけるオピオイドおよび非オピオイド機構の関与 kn-title=Involvement of opioid and non-opioid mechanisms in footshock-induced enhancement of brain histamine turnover in mice en-subtitle= kn-subtitle= en-abstract= kn-abstract= en-copyright= kn-copyright= en-aut-name= en-aut-sei= en-aut-mei= kn-aut-name=吉富一郎 kn-aut-sei=吉富 kn-aut-mei=一郎 aut-affil-num=1 ORCID= affil-num=1 en-affil= kn-affil=岡山大学 END start-ver=1.4 cd-journal=joma no-vol= cd-vols= no-issue= article-no= start-page= end-page= dt-received= dt-revised= dt-accepted= dt-pub-year=1992 dt-pub=19921231 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=癌患者に於ける手術侵襲によるNK細胞活性の抑制とその抑制機構に関する研究 kn-title=Suppression of Natural Killer Cell Activity by Surgical Stress in Cancer Patients and the Underlying Mechanisms en-subtitle= kn-subtitle= en-abstract= kn-abstract= en-copyright= kn-copyright= en-aut-name= en-aut-sei= en-aut-mei= kn-aut-name=吉原久司 kn-aut-sei=吉原 kn-aut-mei=久司 aut-affil-num=1 ORCID= affil-num=1 en-affil= kn-affil=岡山大学 END start-ver=1.4 cd-journal=joma no-vol= cd-vols= no-issue= article-no= start-page= end-page= dt-received= dt-revised= dt-accepted= dt-pub-year=2001 dt-pub=20011231 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=グラム陰性桿菌･陽性球菌起因性の生体防御機構におけるサイトカイン反応の差異:蛋白分解酵素阻害剤gabexate mesilate使用の意義 kn-title=Differential cytokine response in host defense mechanisms triggered by gram-negative and gram-positive bacteria: roles of gabexate mesilate, a synthetic protease inhibitor en-subtitle= kn-subtitle= en-abstract= kn-abstract= en-copyright= kn-copyright= en-aut-name= en-aut-sei= en-aut-mei= kn-aut-name=岩藤浩典 kn-aut-sei=岩藤 kn-aut-mei=浩典 aut-affil-num=1 ORCID= affil-num=1 en-affil= kn-affil=岡山大学 END start-ver=1.4 cd-journal=joma no-vol= cd-vols= no-issue= article-no= start-page= end-page= dt-received= dt-revised= dt-accepted= dt-pub-year=1999 dt-pub=19990331 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=実験的高血圧モデルにおける陰茎血管の構造変化について kn-title=The penis is not protected--in hypertension there are vascular changes in the penis which are similar to those in other vascular beds en-subtitle= kn-subtitle= en-abstract= kn-abstract=In hypertension, small arteries in a variety of vascular beds undergo structural changes that increase resistance. To assess whether there are differential structural changes in the penis that accompany hypertension, we began with determining structurally-based vascular resistance properties in penile and hindlimb vascular beds of adult spontaneously hypertensive rats (SHR) and Sprague-Dawley (SD) rats. In anesthetized SHR, the penile and hindlimb vasculature were isolated and perfused, maximum dilation was induced, and a flow-pressure assessment and alpha 1-adrenoceptor agonist concentration-response curves were generated. Both the baseline and maximum constrictor responses were similar in the two beds of each strain, and overall the maximum structurally-based vascular resistance in SHR was higher than in SD rats. Our data suggests that the penile vasculature is not protected from the structural changes that take place in the other vascular beds in hypertension. There does not appear to be an underlying functional control mechanism that protects the penile vasculature from structural changes that may have a negative impact on penile blood flow. en-copyright= kn-copyright= en-aut-name= en-aut-sei= en-aut-mei= kn-aut-name=岡部浩典 kn-aut-sei=岡部 kn-aut-mei=浩典 aut-affil-num=1 ORCID= affil-num=1 en-affil= kn-affil=岡山大学 en-keyword=erectile dysfunction kn-keyword=erectile dysfunction en-keyword=hypertension kn-keyword=hypertension en-keyword=structural change kn-keyword=structural change en-keyword=penile vasculature kn-keyword=penile vasculature en-keyword=spontaneously hypertensive rats kn-keyword=spontaneously hypertensive rats END start-ver=1.4 cd-journal=joma no-vol= cd-vols= no-issue= article-no= start-page= end-page= dt-received= dt-revised= dt-accepted= dt-pub-year=1998 dt-pub=19980325 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=周期的伸展力に対するウシの線維柱帯細胞のTIMP-1,MMP-2分泌 kn-title=Bovine Trabecular Cells Produce TIMP-1 and MMP-'2 in Response to Mechanical Stretching en-subtitle= kn-subtitle= en-abstract= kn-abstract= en-copyright= kn-copyright= en-aut-name= en-aut-sei= en-aut-mei= kn-aut-name=岡田由美子 kn-aut-sei=岡田 kn-aut-mei=由美子 aut-affil-num=1 ORCID= affil-num=1 en-affil= kn-affil=岡山大学 END start-ver=1.4 cd-journal=joma no-vol= cd-vols= no-issue= article-no= start-page= end-page= dt-received= dt-revised= dt-accepted= dt-pub-year=1990 dt-pub=19900930 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=MLR抑制因子を産生するヒトT細胞ハイブリドーマの樹立:ドナー特異的輸血の作用メカニズムとの関係 kn-title=Establishment of a Human T Cell Hybridoma Producing an MLR Suppressing Factor:Relationship to the Mechanism of Action of Donor-Specific Transfusion (DST) en-subtitle= kn-subtitle= en-abstract= kn-abstract= en-copyright= kn-copyright= en-aut-name= en-aut-sei= en-aut-mei= kn-aut-name=羽井佐実 kn-aut-sei=羽井佐 kn-aut-mei=実 aut-affil-num=1 ORCID= affil-num=1 en-affil= kn-affil=岡山大学 END start-ver=1.4 cd-journal=joma no-vol= cd-vols= no-issue= article-no= start-page= end-page= dt-received= dt-revised= dt-accepted= dt-pub-year=1991 dt-pub=19911231 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=羊水中ドパミン産生機構 kn-title=The Production Mechanism of Amniotic Fluid Dopamine in Rats en-subtitle= kn-subtitle= en-abstract= kn-abstract= en-copyright= kn-copyright= en-aut-name= en-aut-sei= en-aut-mei= kn-aut-name=井上和則 kn-aut-sei=井上 kn-aut-mei=和則 aut-affil-num=1 ORCID= affil-num=1 en-affil= kn-affil=岡山大学 END start-ver=1.4 cd-journal=joma no-vol= cd-vols= no-issue= article-no= start-page= end-page= dt-received= dt-revised= dt-accepted= dt-pub-year=1992 dt-pub=19920331 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=辺縁系発作重積状態と海馬神経細胞脱落の成因について: deep Prepyriform cortex への間欠的電気刺激によるラット重積モデルを用いた実験的研究 kn-title=Mechanisms in the development of limbic status epilepticus and hippocampal neuron loss : an experimental study in a model of status epileticus induced by kindling-like electrical stimulation of the deep prepyriform cortex in rats en-subtitle= kn-subtitle= en-abstract= kn-abstract= en-copyright= kn-copyright= en-aut-name= en-aut-sei= en-aut-mei= kn-aut-name=井上光太郎 kn-aut-sei=井上 kn-aut-mei=光太郎 aut-affil-num=1 ORCID= affil-num=1 en-affil= kn-affil=岡山大学 END start-ver=1.4 cd-journal=joma no-vol= cd-vols= no-issue= article-no= start-page= end-page= dt-received= dt-revised= dt-accepted= dt-pub-year=1996 dt-pub=19960325 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=新しいアプローチによるラット心筋スライスの機械的無負荷状態での心筋酸素消費量 kn-title=Myocardial oxygen consumption of mechanically unloaded contraction of rat ventricular slices by a new approach en-subtitle= kn-subtitle= en-abstract= kn-abstract= en-copyright= kn-copyright= en-aut-name=YasuharaShingo en-aut-sei=Yasuhara en-aut-mei=Shingo kn-aut-name=安原伸吾 kn-aut-sei=安原 kn-aut-mei=伸吾 aut-affil-num=1 ORCID= affil-num=1 en-affil= kn-affil=岡山大学 en-keyword=rat ventricular slices kn-keyword=rat ventricular slices en-keyword=Myocardial oxygen consumption kn-keyword=Myocardial oxygen consumption en-keyword=mechanically unloaded contraction kn-keyword=mechanically unloaded contraction END start-ver=1.4 cd-journal=joma no-vol= cd-vols= no-issue= article-no= start-page= end-page= dt-received= dt-revised= dt-accepted= dt-pub-year=2001 dt-pub=20010325 dt-online= en-article= kn-article= en-subject= kn-subject= en-title=周期的伸展力による網膜細胞のTIMP-1, TIMP-2の産生増加 kn-title=Retinal Cells Produce TIMP-1 and TIMP-2 in Response to Cyclic Mechanical Stretching en-subtitle= kn-subtitle= en-abstract= kn-abstract= en-copyright= kn-copyright= en-aut-name=NanbaMasako en-aut-sei=Nanba en-aut-mei=Masako kn-aut-name=難波雅子 kn-aut-sei=難波 kn-aut-mei=雅子 aut-affil-num=1 ORCID= affil-num=1 en-affil= kn-affil=岡山大学 en-keyword=TIMP-1 kn-keyword=TIMP-1 en-keyword=TIMP-2 kn-keyword=TIMP-2 en-keyword=Cyclic Mechanical Stretching kn-keyword=Cyclic Mechanical Stretching END