result 1628 件
| FullText URL | fulltext.pdf suppl1.tiff suppl2.tif suppl3.tiff suppl4.tiff suppl5.tif suppl6.pdf suppl7.pdf |
|---|---|
| Author | Takii, Takemasa| Yamada, Hiroyuki| Motozono, Chihiro| Yamasaki, Sho| Torrelles, Jordi B.| Turner, Joanne| Kimishima, Aoi| Asami, Yukihiro| Ohara, Naoya| Hida, Shigeaki| Hayashi, Hidetoshi| Onozaki, Kikuo| |
| Keywords | Mycobacterium tuberculosis pyroptosis caspase RNA-Seq cytokine fibroblasts |
| Published Date | 2025-05-19 |
| Publication Title | mSphere |
| Volume | volume10 |
| Issue | issue6 |
| Publisher | American Society for Microbiology |
| Start Page | e00110-25 |
| ISSN | 2379-5042 |
| Content Type | Journal Article |
| language | English |
| OAI-PMH Set | 岡山大学 |
| Copyright Holders | © 2025 Takii et al. |
| File Version | publisher |
| PubMed ID | 40387341 |
| DOI | 10.1128/msphere.00110-25 |
| Web of Science KeyUT | 001490320400001 |
| Related Url | isVersionOf https://doi.org/10.1128/msphere.00110-25 |
| FullText URL | fulltext.pdf |
|---|---|
| Author | Nagamitsu, Shinichiro| Okada, Ayumi| Sakuta, Ryoichi| Ishii, Ryuta| Koyanagi, Kenshi| Habukawa, Chizu| Katayama, Takashi| Ito, Masaya| Kanie, Ayako| Otani, Ryoko| Inoue, Takeshi| Kitajima, Tasuku| Matsubara, Naoki| Tanaka, Chie| Fujii, Chikako| Shigeyasu, Yoshie| Matsuoka, Michiko| Kakuma, Tatsuyuki| Horikoshi, Masaru| |
| Keywords | smartphone cognitive behavioral therapy application adolescent youth teen pediatric mental health psychoeducation self-monitoring questionnaire depressive symptoms effectiveness Japan statistical analysis single-arm uncontrolled study mobile phone |
| Published Date | 2025-07-29 |
| Publication Title | JMIR Formative Research |
| Volume | volume9 |
| Publisher | JMIR Publications Inc. |
| Start Page | e60943 |
| ISSN | 2561-326X |
| Content Type | Journal Article |
| language | English |
| OAI-PMH Set | 岡山大学 |
| Copyright Holders | © Shinichiro Nagamitsu, Ayumi Okada, Ryoichi Sakuta, Ryuta Ishii, Kenshi Koyanagi, Chizu Habukawa, Takashi Katayama, Masaya Ito, Ayako Kanie, Ryoko Otani, Takeshi Inoue, Tasuku Kitajima, Naoki Matsubara, Chie Tanaka, Chikako Fujii, Yoshie Shigeyasu, Michiko Matsuoka, Tatsuyuki Kakuma, Masaru Horikoshi. |
| File Version | publisher |
| PubMed ID | 40729958 |
| DOI | 10.2196/60943 |
| Related Url | isVersionOf https://doi.org/10.2196/60943 |
| FullText URL | fulltext.pdf |
|---|---|
| Author | Segi, Naoki| Nakashima, Hiroaki| Ito, Sadayuki| Ouchida, Jun| Shiratani, Yuki| Shimizu, Takaki| Suzuki, Akinobu| Terai, Hidetomi| Kakutani, Kenichiro| Kanda, Yutaro| Tominaga, Hiroyuki| Kawamura, Ichiro| Ishihara, Masayuki| Paku, Masaaki| Takahashi, Yohei| Funaba, Masahiro| Funayama, Toru| Nakajima, Hideaki| Akeda, Koji| Hirai, Takashi| Inoue, Hirokazu| Nakanishi, Kazuo| Funao, Haruki| Oshigiri, Tsutomu| Otsuki, Bungo| Kobayakawa, Kazu| Tanishima, Shinji| Hashimoto, Ko| Iimura, Takuya| Sawada, Hirokatsu| Uotani, Koji| Manabe, Hiroaki| Iwai, Chizuo| Yamabe, Daisuke| Hiyama, Akihiko| Seki, Shoji| Goto, Yuta| Miyazaki, Masashi| Watanabe, Kazuyuki| Nakamae, Toshio| Kaito, Takashi| Nagoshi, Narihito| Kato, Satoshi| Watanabe, Kota| Imagama, Shiro| Inoue, Gen| Furuya, Takeo| |
| Keywords | spinal metastasis metastasis segment palliative surgery quality of life activities of daily living pain anxiety |
| Published Date | 2024-11 |
| Publication Title | Global Spine Journal |
| Volume | volume15 |
| Issue | issue4 |
| Publisher | SAGE Publications |
| Start Page | 2286 |
| End Page | 2299 |
| ISSN | 2192-5682 |
| NCID | AA12633225 |
| Content Type | Journal Article |
| language | English |
| OAI-PMH Set | 岡山大学 |
| Copyright Holders | © The Author(s) 2024 |
| File Version | publisher |
| PubMed ID | 39484810 |
| DOI | 10.1177/21925682241297948 |
| Web of Science KeyUT | 001346141500001 |
| Related Url | isVersionOf https://doi.org/10.1177/21925682241297948 |
| FullText URL | fulltext.pdf suppl.docx |
|---|---|
| Author | Fortmeier, Vera| Lachmann, Mark| Stolz, Lukas| von Stein, Jennifer| Rommel, Karl-Philipp| Kassar, Mohammad| Gerçek, Muhammed| Schöber, Anne R.| Stocker, Thomas J.| Omran, Hazem| Fett, Michelle| Tervooren, Jule| Körber, Maria I.| Hesse, Amelie| Harmsen, Gerhard| Friedrichs, Kai Peter| Yuasa, Shinsuke| Rudolph, Tanja K.| Joner, Michael| Pfister, Roman| Baldus, Stephan| Laugwitz, Karl-Ludwig| Windecker, Stephan| Praz, Fabien| Lurz, Philipp| Hausleiter, Jörg| Rudolph, Volker| |
| Keywords | machine learning transcatheter tricuspid valve intervention tricuspid regurgitation |
| Published Date | 2025-02 |
| Publication Title | JACC: Advances |
| Volume | volume4 |
| Issue | issue2 |
| Publisher | Elsevier BV |
| Start Page | 101575 |
| ISSN | 2772-963X |
| Content Type | Journal Article |
| language | English |
| OAI-PMH Set | 岡山大学 |
| Copyright Holders | © 2025 The Authors. |
| File Version | publisher |
| PubMed ID | 39848099 |
| DOI | 10.1016/j.jacadv.2024.101575 |
| Web of Science KeyUT | 001493699800001 |
| Related Url | isVersionOf https://doi.org/10.1016/j.jacadv.2024.101575 |
| FullText URL | fulltext.pdf suppl1.docx suppl2.docx |
|---|---|
| Author | Sasayama, Kensaku| Yasunebe, Jin| Adachi, Minoru| |
| Keywords | Physical activity Step counts Moderate-to-vigorous physical activity Youth Recess Physical education Longitudinal study Tracking |
| Published Date | 2025-03-18 |
| Publication Title | BMC Public Health |
| Volume | volume25 |
| Issue | issue1 |
| Publisher | Springer Science and Business Media LLC |
| Start Page | 1041 |
| ISSN | 1471-2458 |
| Content Type | Journal Article |
| language | English |
| OAI-PMH Set | 岡山大学 |
| Copyright Holders | © The Author(s) 2025. |
| File Version | author |
| PubMed ID | 40102823 |
| DOI | 10.1186/s12889-025-22256-8 |
| Web of Science KeyUT | 001449530200009 |
| Related Url | isVersionOf https://doi.org/10.1186/s12889-025-22256-8 |
| FullText URL | fulltext.pdf |
|---|---|
| Author | Tsukioki, Takahiro| Takata, Nozomu| Dennis, Saya R.| Terata, Kaori| Sagara, Yasuaki| Sakai, Takehiko| Takayama, Shin| Kitagawa, Dai| Kikawa, Yuichiro| Takahashi, Yuko| Iwatani, Tsuguo| Hara, Fumikata| Fujisawa, Tomomi| Shien, Tadahiko| |
| Keywords | Breast cancer FACT-B FACT-B+4 QOL |
| Note | The version of record of this article, first published in Breast Cancer, is available online at Publisher’s website: http://dx.doi.org/10.1007/s12282-025-01701-x| |
| Published Date | 2025-05-08 |
| Publication Title | Breast Cancer |
| Volume | volume32 |
| Issue | issue4 |
| Publisher | Springer Science and Business Media LLC |
| Start Page | 773 |
| End Page | 782 |
| ISSN | 1340-6868 |
| NCID | AA1103354X |
| Content Type | Journal Article |
| language | English |
| OAI-PMH Set | 岡山大学 |
| Copyright Holders | © The Author(s) 2025 |
| File Version | publisher |
| PubMed ID | 40338515 |
| DOI | 10.1007/s12282-025-01701-x |
| Web of Science KeyUT | 001483857300001 |
| Related Url | isVersionOf https://doi.org/10.1007/s12282-025-01701-x |
| JaLCDOI | 10.18926/AMO/68725 |
|---|---|
| FullText URL | 79_3_177.pdf |
| Author | Furuichi, Shuro| Mitani, Shigeru| Endo, Hirosuke| Namba, Yoshifumi| Kawamoto, Toyohiro| |
| Abstract | The position attained in total hip arthroplasty (THA) is ideally in the center of the horizontal plane of the acetabulum. However, central placement is not always possible. We hypothesized that differences in approach result in individual differences in cup positioning; thus, we investigated the cup positions of 217 hips that underwent THA. The acetabulum’s anteroposterior diameter was measured, and the cups placed within 2 mm of the line perpendicular to the center as a central placement (central). Of the 217 hips, 68, 114, and 35 hips were anterior, central, and posterior, respectively. In 21 hips, anteroposterior deviation was noted. Among patients operated using the anterolateral approach, 48, 93, and 30 hips were anterior, central, and posterior, respectively. Among those operated using the posterolateral approach, 16, 20, and 4 hips were anterior, central, and posterior, respectively. The cup position shifted either anteriorly or posteriorly to the acetabulum in approximately half of all hips operated using both approaches and tended to shift anteriorly in the hips operated using the posterolateral approach. During THA surgery, it is important to operate with awareness of the center of the acetabulum. |
| Keywords | total hip arthroplasty cup horizontal position total hip arthroplasty approach navigation system computed tomography |
| Amo Type | Original Article |
| Publication Title | Acta Medica Okayama |
| Published Date | 2025-06 |
| Volume | volume79 |
| Issue | issue3 |
| Publisher | Okayama University Medical School |
| Start Page | 177 |
| End Page | 184 |
| ISSN | 0386-300X |
| NCID | AA00508441 |
| Content Type | Journal Article |
| language | English |
| Copyright Holders | Copyright Ⓒ 2025 by Okayama University Medical School |
| File Version | publisher |
| Refereed | True |
| JaLCDOI | 10.18926/AMO/68724 |
|---|---|
| FullText URL | 79_3_167.pdf |
| Author | Kanaji, Nobuhiro| Nishii, Kazuya| Tsubata, Yukari| Nakao, Mika| Okuno, Takae| Okawa, Sachi| Takata, Kenji| Kodani, Masahiro| Yamasaki, Masahiro| Fujitaka, Kazunori| Kubota, Tetsuya| Inoue, Masaaki| Watanabe, Naoki| Hotta, Katsuyuki| CS-Lung-003 Investigator| |
| Abstract | This prospective observational study investigated the clinical status of patients with advanced non-small cell lung cancer (NSCLC) treated with cytotoxic chemotherapy+an immune checkpoint inhibitor (chemo + IO) as first-line treatment in a real-world setting. The cases of 98 patients treated with chemo + IO were prospectively collected and analyzed for effectiveness and safety. The response rate to chemo + IO was 46.9%, and the disease control rate was 76.5%. The median progression-free survival and overall survival (OS) in the total population were 5.2 and 22.3 months, respectively. The patients positive for PD-L1 (≥ 1%) showed significantly longer OS than the negative group (<1%) (median 26.7 vs. 18.7 months, p=0.04). Pre-existing interstitial lung disease (ILD) was associated with shorter OS than the absence of ILD (median 9.0 vs. 22.6 months, p<0.01). Immunerelated adverse events (irAEs) were observed in 28 patients (28.6%). The most frequent irAE was ILD (n=11); Grade 1 (n=1 patient), G2 (n=5), G3 (n=4), and only a single patient with a G5 irAE. In this CS-Lung-003 study, first-line chemo + IO in a real-world setting showed good effectiveness, comparable to that observed in international clinical trials. In real-world practice, chemo + IO is a promising and steadfast strategy. |
| Keywords | non-small cell lung cancer real-world first-line immune checkpoint inhibitor combined immunotherapy |
| Amo Type | Original Article |
| Publication Title | Acta Medica Okayama |
| Published Date | 2025-06 |
| Volume | volume79 |
| Issue | issue3 |
| Publisher | Okayama University Medical School |
| Start Page | 167 |
| End Page | 176 |
| ISSN | 0386-300X |
| NCID | AA00508441 |
| Content Type | Journal Article |
| language | English |
| Copyright Holders | Copyright Ⓒ 2025 by Okayama University Medical School |
| File Version | publisher |
| Refereed | True |
| JaLCDOI | 10.18926/AMO/68723 |
|---|---|
| FullText URL | 79_3_157.pdf |
| Author | Hatipoglu, Omer Faruk| Nishinaka, Takashi| Yaykasli, Kursat Oguz| Mori, Shuji| Watanabe, Masahiro| Toyomura, Takao| Nishibori, Masahiro| Hirohata, Satoshi| Takahashi, Hideo| Wake, Hidenori| |
| Abstract | Chondrocytes are responsible for the production of extracellular matrix (ECM) components such as collagen type II alpha-1 (COL2A1) and aggrecan, which are loosely distributed in articular cartilage. Chondrocyte dysfunction has been implicated in the pathogenesis of rheumatic diseases such as osteoarthritis (OA) and rheumatoid arthritis (RA). With age, advanced glycation end products (AGEs) accumulate in all tissues and body fluids, including cartilage and synovial fluid, causing and accelerating pathological changes associated with chronic diseases such as OA. Glycolaldehyde-derived AGE (AGE3), which is toxic to a variety of cell types, have a stronger effect on cartilage compared with other AGEs. To understand the long-term effects of AGE3 on cartilage, we stimulated a human chondrosarcoma cell line (OUMS-27), which exhibits a chondrocytic phenotype, with 10 μg/ml AGE3 for 4 weeks. As a result, the expressions of COL2A1 and aggrecan were significantly downregulated in the OUMS-27 cells without inducing cell death, but the expressions of proteases that play an important role in cartilage destruction were not affected. Inhibition of the receptor for advanced glycation end products (RAGE) suppressed the AGE3-induced reduction in cartilage component production, suggesting the involvement of RAGE in the action of AGE3. |
| Keywords | advanced glycation end product aging cartilage collagen aggrecan |
| Amo Type | Original Article |
| Publication Title | Acta Medica Okayama |
| Published Date | 2025-06 |
| Volume | volume79 |
| Issue | issue3 |
| Publisher | Okayama University Medical School |
| Start Page | 157 |
| End Page | 166 |
| ISSN | 0386-300X |
| NCID | AA00508441 |
| Content Type | Journal Article |
| language | English |
| Copyright Holders | Copyright Ⓒ 2025 by Okayama University Medical School |
| File Version | publisher |
| Refereed | True |
| FullText URL | fulltext.pdf |
|---|---|
| Author | Takatori, S.| Pimon, M.| Pollitt, S.| Bartokos, M.| Beeks, K.| Grueneis, A.| Hiraki, T.| Honma, T.| Hosseini, N.| Leitner, A.| Masuda, T.| Morawetz, I| Nitta, K.| Okai, K.| Riebner, T.| Schaden, F.| Schumm, T.| Sekizawa, O.| Sikorsky, T.| Takahashi, Y.| De Col, Col, L. Toscani| Yamamoto, R.| Yomogida, T.| Yoshimi, A.| Yoshimura, K.| |
| Keywords | solid-state nuclear clock thorium-229 XAFS |
| Published Date | 2025-04-28 |
| Publication Title | New Journal of Physics |
| Volume | volume27 |
| Issue | issue4 |
| Publisher | IOP Publishing |
| Start Page | 043024 |
| ISSN | 1367-2630 |
| Content Type | Journal Article |
| language | English |
| OAI-PMH Set | 岡山大学 |
| Copyright Holders | © 2025 The Author(s). |
| File Version | publisher |
| DOI | 10.1088/1367-2630/adce22 |
| Web of Science KeyUT | 001477975100001 |
| Related Url | isVersionOf https://doi.org/10.1088/1367-2630/adce22 |
| Title Alternative | The 2023 Incentive Award of the Okayama Medical Association in General Medical Science (2023 Yuuki Prize) |
|---|---|
| Author | Sumii, Yuichi| |
| Publication Title | Journal of Okayama Medical Association |
| Published Date | 2025-04-01 |
| Volume | volume137 |
| Issue | issue1 |
| Start Page | 4 |
| End Page | 6 |
| ISSN | 0030-1558 |
| Related Url | isVersionOf https://doi.org/10.4044/joma.137.4 |
| language | Japanese |
| Copyright Holders | Copyright (c) 2025 岡山医学会 |
| File Version | publisher |
| DOI | 10.4044/joma.137.4 |
| FullText URL | fulltext.pdf |
|---|---|
| Author | Kong, Dezheng| Funabiki, Nobuo| Fang, Shihao| Noprianto, Mitsuhiro| Okayasu, Mitsuhiro| Puspitaningayu, Pradini| |
| Keywords | creep test Raspberry Pi dial gauge needle reading smart lighting |
| Published Date | 2025-04-02 |
| Publication Title | Technologies |
| Volume | volume13 |
| Issue | issue4 |
| Publisher | MDPI |
| Start Page | 139 |
| ISSN | 2227-7080 |
| Content Type | Journal Article |
| language | English |
| OAI-PMH Set | 岡山大学 |
| Copyright Holders | © 2025 by the authors. |
| File Version | publisher |
| DOI | 10.3390/technologies13040139 |
| Web of Science KeyUT | 001474287400001 |
| Related Url | isVersionOf https://doi.org/10.3390/technologies13040139 |
| FullText URL | fulltext.pdf |
|---|---|
| Author | Honda, Manami| Iwamuro, Masaya| Tanaka, Takehiro| Yamasaki, Yasushi| Kawano, Seiji| Hiraoka, Sakiko| Kawahara, Yoshiro| Otsuka, Motoyuki| |
| Keywords | colonoscopy esophagogastroduodenoscopy gastrointestinal neoplasms gastrointestinal stromal tumor neurofibromatosis |
| Published Date | 2025-04-16 |
| Publication Title | JGH Open |
| Volume | volume9 |
| Issue | issue4 |
| Publisher | Wiley |
| Start Page | e70151 |
| ISSN | 2397-9070 |
| Content Type | Journal Article |
| language | English |
| OAI-PMH Set | 岡山大学 |
| Copyright Holders | © 2025 The Author(s). |
| File Version | publisher |
| PubMed ID | 40247846 |
| DOI | 10.1002/jgh3.70151 |
| Web of Science KeyUT | 001468535400001 |
| Related Url | isVersionOf https://doi.org/10.1002/jgh3.70151 |
| JaLCDOI | 10.18926/AMO/68652 |
|---|---|
| FullText URL | 79_2_129.pdf |
| Author | Tsuji, Akihiro| Shiode, Yusuke| Kimura, Shuhei| Hosokawa, Mio| Matoba, Ryo| Morita, Tetsuro| Takahashi, Kosuke| Morizane, Yuki| |
| Abstract | A 66-year-old woman presented with significant anterior capsule contraction and intraocular lens dislocation in both eyes 4 months after cataract surgery. Postoperative examinations such as fluorescein angiography, Goldmann perimetry, and electroretinography revealed retinitis pigmentosa (RP). Patients with significant anterior capsule contraction after cataract surgery should be closely examined because RP may be a contributing factor. |
| Keywords | retinitis pigmentosa intraocular lens anterior capsule contraction |
| Amo Type | Case Report |
| Publication Title | Acta Medica Okayama |
| Published Date | 2025-04 |
| Volume | volume79 |
| Issue | issue2 |
| Publisher | Okayama University Medical School |
| Start Page | 129 |
| End Page | 134 |
| ISSN | 0386-300X |
| NCID | AA00508441 |
| Content Type | Journal Article |
| language | English |
| Copyright Holders | Copyright Ⓒ 2025 by Okayama University Medical School |
| File Version | publisher |
| Refereed | True |
| PubMed ID | 40302285 |
| Web of Science KeyUT | 001485535700001 |
| JaLCDOI | 10.18926/AMO/68649 |
|---|---|
| FullText URL | 79_2_109.pdf |
| Author | Awai, Kyoko| Nakatsuka, Mikiya| |
| Abstract | The status of postpartum depression was elucidated herein with the use of the Edinburgh Postnatal Depression Scale (EPDS) in women in Shikoku, Japan who became pregnant and gave birth after undergoing infertility treatment, including assisted reproductive technology (ART). The assessment was performed during their children’s 4-month health examination. The relationships between postpartum depression and the mothers’ background factors and scores on the Big Five personality traits scale were also examined. Of the Big Five personality traits, the scores for neuroticism were significantly higher in the ART group (n=71) than in the general infertility treatment (n=118) and natural pregnancy (n=872) groups. No significant differences in EPDS scores were seen among these three groups. A logistic regression analysis showed that neuroticism was associated with an EPDS score ≧9 points, (which is suggestive of postpartum depression, ) in all groups. Moreover, although a long-standing marriage had an inhibitory effect on postpartum depression in the natural pregnancy group, no such trend was seen in the ART group, which included many women with long-standing marriages. Particularly for women who become pregnant by ART, an individualized response that pays close attention to the woman’s personality traits is needed. |
| Keywords | infertility treatment assisted reproductive technology postpartum postpartum depression personality trait |
| Amo Type | Original Article |
| Publication Title | Acta Medica Okayama |
| Published Date | 2025-04 |
| Volume | volume79 |
| Issue | issue2 |
| Publisher | Okayama University Medical School |
| Start Page | 109 |
| End Page | 116 |
| ISSN | 0386-300X |
| NCID | AA00508441 |
| Content Type | Journal Article |
| language | English |
| Copyright Holders | Copyright Ⓒ 2025 by Okayama University Medical School |
| File Version | publisher |
| Refereed | True |
| PubMed ID | 40302282 |
| Web of Science KeyUT | 001485544200006 |
| JaLCDOI | 10.18926/AMO/68648 |
|---|---|
| FullText URL | 79_2_101.pdf |
| Author | Isozaki, Hiroshi| Matsumoto, Sasau| Takama, Takehiro| Isozaki, Yuka| |
| Abstract | To evaluate the effectiveness of postoperative irradiation (POI) for patients with cN0 early breast cancer, we retrospectively analyzed the cases of 650 consecutive breast cancer patients who underwent sentinel lymph node (SLN)-guided surgery (2005-2022) at our hospital. In this cohort, 53% (278/521) of the patients who underwent breast conservative surgery (BCS) and 96% (124/129) of those treated with mastectomy did not receive POI. The patients who underwent BCS were treated with POI using opposing tangential field irradiation. A false negative (FN) SLN was retrospectively defined as a negative metastasis in SLN plus positive recurrence in the axillary lymph nodes. Recurrence was detected in 83 patients. A logistic regression analysis revealed that the nuclear grade (odds ratio [OR] 1.69), POI (OR 0.41), and postoperative hormone therapy (OR 0.40) were each significantly related to recurrence. The 26.1% (12/46) FN rate of the non-POI patients decreased to 5.8% (1/17) compared to those treated with POI. The rate of axillary recurrence was significantly lower in the POI group (0.4%) versus the non-POI group (2.7%) (p=0.0355). The rate of locoregional recurrence was also significantly lower in the POI group (2.0%) versus the non-POI group (13.4%) (p<0.0001). No significant difference was observed in the rate of distant recurrence between the POI (4.0%) and non-POI (3.3%) (p=0.831) groups. These results indicated that the postoperative opposing tangential field irradiation of conserved breast tissue inhibited recurrence in the axillary lymph nodes. |
| Keywords | breast cancer postoperative irradiation radiation therapy sentinel lymph nodes recurrence |
| Amo Type | Original Article |
| Publication Title | Acta Medica Okayama |
| Published Date | 2025-04 |
| Volume | volume79 |
| Issue | issue2 |
| Publisher | Okayama University Medical School |
| Start Page | 101 |
| End Page | 107 |
| ISSN | 0386-300X |
| NCID | AA00508441 |
| Content Type | Journal Article |
| language | English |
| Copyright Holders | Copyright Ⓒ 2025 by Okayama University Medical School |
| File Version | publisher |
| Refereed | True |
| PubMed ID | 40302281 |
| Web of Science KeyUT | 001485544200005 |
| JaLCDOI | 10.18926/AMO/68647 |
|---|---|
| FullText URL | 79_2_093.pdf |
| Author | Tsuchie, Rina| Fukuda, Mari| Tsumura, Hideki| Kinuta, Minako| Hisamatsu, Takashi| Kanda, Hideyuki| |
| Abstract | School teachers are subject to both physical and mental health problems. We examined cross-sectional relationships between work engagement and major health outcomes among junior and senior high school teachers in Japan via a nationwide survey in 2019-2020. A total of 3,160 respondents were included in the analyses (19.9% response rate). Work engagement was assessed with the Utrecht Work Engagement Scale-9 (UWES-9), and we thus divided the teachers into quartiles according to their UWES-9 scores. Based on validated questionnaires, we assessed insomnia, psychological distress, and neck pain as health outcomes. A binomial logistic regression adjusted for age, gender, school type, teacher’s roles, involvement in club activities, division of duties, employment status, and whether they lived with family demonstrated that the teachers with lower UWES-9 scores had higher burdens of insomnia, psychological distress, and neck pain (odds ratios [95% confidence intervals] in 4th vs. 1st quartile, 2.92 (2.34-3.65), 3.70 (2.81-4.88), and 2.12 (1.68-2.68), respectively; all trend p<0.001). There were no significant differences in these associations between full-time and part-time teachers. Our findings indicate that low work engagement may contribute to physical and mental health issues among junior and senior high school teachers, thus providing insights for preventing health problems in this profession. |
| Keywords | work engagement school teachers insomnia psychological distress neck pain |
| Amo Type | Original Article |
| Publication Title | Acta Medica Okayama |
| Published Date | 2025-04 |
| Volume | volume79 |
| Issue | issue2 |
| Publisher | Okayama University Medical School |
| Start Page | 93 |
| End Page | 100 |
| ISSN | 0386-300X |
| NCID | AA00508441 |
| Content Type | Journal Article |
| language | English |
| Copyright Holders | Copyright Ⓒ 2025 by Okayama University Medical School |
| File Version | publisher |
| Refereed | True |
| PubMed ID | 40302280 |
| Web of Science KeyUT | 001485544200004 |
| JaLCDOI | 10.18926/AMO/68646 |
|---|---|
| FullText URL | 79_2_081.pdf |
| Author | Kawada, Tatsushi| Kobayashi, Yasuyuki| Tsugawa, Takuji| Tsuboi, Kazuma| Katayama, Satoshi| Iwata, Takehiro| Bekku, Kensuke| Kobayashi, Tomoko| Edamura, Kohei| Ebara, Shin| Araki, Motoo| |
| Abstract | We retrospectively evaluated the oncologic outcomes of paclitaxel, cisplatin, and gemcitabine (PCG) with those of gemcitabine and cisplatin (GC) as neoadjuvant chemotherapy in muscle-invasive bladder cancer (MIBC) patients. The primary outcome was efficacy: pathological complete response (pCR), ypT0N0; and pathological objective response (pOR), ypT0N0, ≤ ypT1N0, or ypT0N1. Secondary outcomes included overall survival (OS), recurrence-free survival (RFS), predictive factors for pOR, OS, and RFS, and hematologic adverse events (AEs). Among 113 patients treated (PCG, n=28; GC, n=85), similar pOR and pCR rates were achieved by the groups (pOR: PCG, 57.1% vs. GC, 49. 4%; p=0.52; pCR: PCG, 39.3% vs. GC, 29.4%; p=0.36). No significant differences were observed in OS (p=1.0) or RFS (p=0.20). Multivariate logistic regression analysis showed that hydronephrosis (odds ratio [OR] 0.32, 95%CI: 0.11-0.92) and clinical node-positive status (cN+) (OR 0.22, 95%CI: 0.050-0.99) were significantly associated with a decreased probability of pOR. On multivariate Cox regression analyses, pOR achievement was associated with improved OS (hazard ratio [HR] 0.23, 95%CI: 0.10-0.56) and RFS (HR 0.30, 95%CI: 0.13-0.67). There were no significant between-group differences in the incidence of grade ≥ 3 hematologic AEs or dose-reduction required, but the PCG group had a higher incidence of grade 4 neutropenia. |
| Keywords | urothelial carcinoma paclitaxel cisplatin gemcitabine neoadjuvant |
| Amo Type | Original Article |
| Publication Title | Acta Medica Okayama |
| Published Date | 2025-04 |
| Volume | volume79 |
| Issue | issue2 |
| Publisher | Okayama University Medical School |
| Start Page | 81 |
| End Page | 92 |
| ISSN | 0386-300X |
| NCID | AA00508441 |
| Content Type | Journal Article |
| language | English |
| Copyright Holders | Copyright Ⓒ 2025 by Okayama University Medical School |
| File Version | publisher |
| Refereed | True |
| PubMed ID | 40302279 |
| Web of Science KeyUT | 001485544200003 |
| FullText URL | fulltext.pdf |
|---|---|
| Author | Fujii, Yuki| Matsumoto, Kazuyuki| Matsumi, Akihiro| Miyamoto, Kazuya| Uchida, Daisuke| Horiguchi, Shigeru| Tsutsumi, Koichiro| Mitsuhashi, Toshiharu| Otsuka, Motoyuki| |
| Keywords | adverse events balloon-assisted ERCP benzodiazepine sedation |
| Published Date | 2025-03-27 |
| Publication Title | Journal of Clinical Medicine |
| Volume | volume14 |
| Issue | issue7 |
| Publisher | MDPI |
| Start Page | 2287 |
| ISSN | 2077-0383 |
| Content Type | Journal Article |
| language | English |
| OAI-PMH Set | 岡山大学 |
| Copyright Holders | © 2025 by the authors. |
| File Version | publisher |
| PubMed ID | 40217737 |
| DOI | 10.3390/jcm14072287 |
| Web of Science KeyUT | 001463583200001 |
| Related Url | isVersionOf https://doi.org/10.3390/jcm14072287 |
| FullText URL | fulltext.pdf |
|---|---|
| Author | Matsuo, Toshihiko| Tanaka, Takehiro| Asada, Noboru| Obika, Mikako| Omichi, Ryotaro| Iwatsuki, Keiji| |
| Keywords | corneal infiltration hypopyon myelodysplastic syndromes neutrophilic dermatosis peripheral keratitis pyoderma gangrenosum scleritis sweet syndrome |
| Published Date | 2025-04-16 |
| Publication Title | Cureus |
| Volume | volume17 |
| Issue | issue4 |
| Publisher | Springer Science and Business Media LLC |
| Start Page | e82348 |
| ISSN | 2168-8184 |
| Content Type | Journal Article |
| language | English |
| OAI-PMH Set | 岡山大学 |
| Copyright Holders | © Copyright 2025 Matsuo et al. |
| File Version | publisher |
| DOI | 10.7759/cureus.82348 |
| Related Url | isVersionOf https://doi.org/10.7759/cureus.82348 |
