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Author Kong, Dezheng| Funabiki, Nobuo| Kyaw, Htoo Htoo Sandi| Kotama, I Nyoman Darma| Zhu, Zihao| Rahmadani, Alfiandi Aulia|
Keywords internet of things AI retrieval-augmented generation vector database schema-based extraction data sheet technical information
Published Date 2026-02-07
Publication Title Sensors
Volume volume26
Issue issue4
Publisher MDPI AG
Start Page 1081
ISSN 1424-8220
Content Type Journal Article
language English
OAI-PMH Set 岡山大学
Copyright Holders © 2026 by the authors.
File Version publisher
DOI 10.3390/s26041081
Related Url isVersionOf https://doi.org/10.3390/s26041081
JaLCDOI 10.18926/AMO/70072
FullText URL 80_1_047.pdf
Author Eguchi, Yukiomi| Ushio, Soichiro| Irie, Keiichi| Yamashita, Yuta| Eguchi, Miyu| Nakano, Takafumi| Mishima, Kenichi|
Abstract Deregulation of cannabis use is gradually expanding in Europe and the United States. However, the biological processes driving tolerance to delta-9-tetrahydrocannabinol (Δ9-THC), the main psychoactive component of cannabis, remain unclear. Thus, this study aimed to investigate the mechanisms and time course of tolerance development and loss to Δ9-THC in mice. Male ICR mice (7 weeks old) were administered Δ9-THC once daily for 3 days and then divided into three groups according to the washout period (3-, 10-, and 17-day washout groups). After each washout, changes in body temperature and locomotor activity were measured following re-exposure to Δ9-THC. Furthermore, the mRNA expression levels of CB1 and CB2 receptors in the brain were evaluated using real-time PCR. On day 1, significant hypothermia and reduced spontaneous locomotor activity were observed in the Δ9-THC-treated mice compared with the vehicle-treated mice. Tolerance to the hypothermic and locomotor-suppressing effects of Δ9-THC developed on days 2 and 3, respectively, and dissipated after 3 and 11 days of washout, respectively. These differences in the rates of tolerance development and recovery may reflect distinct underlying mechanisms. No significant changes in receptor mRNA expression were observed. These findings highlight the complexity of Δ9-THC tolerance and its potential implications for long-term cannabis use.
Keywords delta-9-tetrahydrocannabinol cannabis tolerance locomotor hypothermic
Amo Type Original Article
Publication Title Acta Medica Okayama
Published Date 2026-02
Volume volume80
Issue issue1
Publisher Okayama University Medical School
Start Page 47
End Page 54
ISSN 0386-300X
NCID AA00508441
Content Type Journal Article
language English
Copyright Holders Copyright Ⓒ 2026 by Okayama University Medical School
File Version publisher
Refereed True
PubMed ID 41748149
Web of Science KeyUT 001712994500006
JaLCDOI 10.18926/AMO/70068
FullText URL 80_1_009.pdf
Author Sugahara, Kentaro| Kondo, Takashi| Miyatake, Nobuyuki| Nishi, Hiroyuki| Ujike, Kazuhiro| Koumoto, Kiichi| Namio, Keiichi| Hishii, Shuhei| Katayama, Akihiko| Suzuki, Hiromi| Yamamoto, Yorimasa|
Abstract Appropriate treatments for chronic hemodialysis patients are a public health challenge in Japan. Sedentary behavior appears to be closely associated with these patients’ survival. We thus sought to develop a nomogram that predicts survival based on the duration of chronic hemodialysis patients’ sedentary behavior. One hundred twenty-four patients under chronic hemodialysis (73 men, 51 women, age 71.7±11.1 years) were enrolled in this cohort study. The patients wore a triaxial accelerometer that measured both their sedentary behavior, i.e., total sedentary behavior (minutes) and their maximum sedentary bouts (min) on non-hemodialysis days. We obtained the Kaplan-Meier curve and used the log-rank test and a Cox proportional hazards model to evaluate the relationship between the patients’ sedentary behavior and their survival. We also used a Cox proportional hazards model to develop a nomogram for the patients’ 5-year survival rate. Forty-six patients died during the follow-up period. When we stratified the patients by the medians of total sedentary behavior and maximum sedentary bouts, we observed significant between-group differences. After adjustment for confounding factors in a Cox proportional hazards model, total sedentary behavior and maximum sedentary bouts were identified as critical survival factors, and we generated a nomogram using an index of sedentary behavior. Our analysis results demonstrated that sedentary behavior on non-dialysis days was closely associated with the survival of the chronic hemodialysis patients, suggesting that a decrease in sedentary behavior would prolong their survival. The nomogram developed herein based on sedentary behavior may be useful for predicting the outcomes of chronic hemodialysis patients.
Keywords nomogram chronic hemodialysis sedentary behavior Cox proportional hazards model Kaplan- Meier curve
Amo Type Original Article
Publication Title Acta Medica Okayama
Published Date 2026-02
Volume volume80
Issue issue1
Publisher Okayama University Medical School
Start Page 9
End Page 16
ISSN 0386-300X
NCID AA00508441
Content Type Journal Article
language English
Copyright Holders Copyright Ⓒ 2026 by Okayama University Medical School
File Version publisher
Refereed True
PubMed ID 41748145
Web of Science KeyUT 001712994500002
JaLCDOI 10.18926/AMO/70067
FullText URL 80_1_001.pdf
Author Yamaoka, Hidenaru| Yoshida, Masashi| Sarashina, Toshihiro| Akagi, Satoshi| Miyoshi, Toru| Munemasa, Mitsuru| Nakamura, Kazufumi| Ito, Hiroshi| Yuasa, Shinsuke|
Abstract Venous thromboembolism (VTE) is a serious complication in patients with cancer. In this population, the presence of thrombi is often assessed at cancer diagnosis by measuring D-dimer levels, which have high sensitivity but low specificity for identifying VTE at this clinical time point. However, the usefulness of D-dimer measurement during anticoagulation therapy has not been fully established, despite its widespread use. In this retrospective observational study, we investigated whether D-dimer measurement during anticoagulation therapy in cancer patients could predict overt VTE at follow-up. The study included patients who underwent D-dimer testing and contrast-enhanced computed tomography between 30 and 100 days after initiation of anticoagulation therapy. Eighty-two patients were included: 60 with cancer and 22 without. The diagnostic performance of D-dimer for overt VTE was as follows: sensitivity, 85.7%; specificity, 87.2%; positive predictive value, 78.3%; and negative predictive value, 89.2%. These findings suggest that D-dimer measurement at follow-up has high sensitivity and specificity for overt VTE in cancer patients and may aid in assessing thrombotic status. Clinically, if anticoagulation therapy is continued until D-dimer levels become negative, the absence of overt VTE could be inferred without additional invasive testing.
Keywords D-dimer venous thromboembolism cancer
Amo Type Original Article
Publication Title Acta Medica Okayama
Published Date 2026-02
Volume volume80
Issue issue1
Publisher Okayama University Medical School
Start Page 1
End Page 7
ISSN 0386-300X
NCID AA00508441
Content Type Journal Article
language English
Copyright Holders Copyright Ⓒ 2026 by Okayama University Medical School
File Version publisher
Refereed True
PubMed ID 41748144
Web of Science KeyUT 001712994500001
Title Alternative Radiocarbon dating, dietary habits, and genetic characteristics of ancient skeletal remains excavated from the Inome Cave Site in Shimane Prefecture
JaLCDOI 10.18926/70052
FullText URL jdc_005_020.pdf
Author KANZAWA-KIRIYAMA, Hideaki| TAKIGAMI, Mai| KAKUDA, Tsuneo| SPEIDEL, Leo| HELLENTHAL, Garrett| BIRD, Nancy| KAWAI, Yousuke| NCBN Controls WGS Consortium| SAKAMOTO, Minoru| KAMEDA, Yuichi| ADACHI, Noboru| SHINODA, Ken-ichi| SAITOU, Naruya| HAMADA, Tatsuhiko|
Abstract This paper reports on the integrative research findings of the human bones excavated from the Inome Cave Site in Shimane Prefecture, based on dietary estimation using carbon and nitrogen isotope analysis, radiocarbon dating, and whole genome analysis. The dates of the analyzed human bones span a wide range, from the Middle to Late Kofun period, the Nara period to the Early Heian period, and the Middle to Late Heian period, indicating that the Inome Cave Site was continuously used as a burial place. Dietary habits were a mixture of C3 resources (C3 plants and terrestrial animals that consumed C3 plants) and marine resources, with individual variations in the intake of marine and terrestrial resources. A correlation was observed between differences in dietary habits and individual variations in the Jomon ratio in the nuclear genome, with individuals who consumed higher amounts of marine resources tending to have a higher Jomon ratio. This suggests that individuals with different backgrounds were buried in the same site due to interactions with surrounding settlements.
Keywords Inome Cave Site human bone radiocarbon dating dietary habits ancient genome
Amo Type 論文 (Research article)
Publication Title Dynamics of Civilizations
Published Date 2026-03
Volume volume5
Publisher 岡山大学文明動態学研究所
Start Page 20
End Page 39
ISSN 2436-8326
Content Type Journal Article
language Japanese
Copyright Holders © 2025 by RIDC
File Version publisher
FullText URL fulltext.pdf
Author Nishida, Keiichiro| Nasu, Yoshihisa| Harada, Ryozo| Nakahara, Ryuichi| Horita, Masahiro| Natsumeda, Masamitsu| Naniwa, Shuichi| Ozaki, Toshifumi|
Keywords delayed wound healing discontinuation ozoralizumab orthopaedic surgery perioperative management rheumatoid arthritis surgical site infection
Published Date 2026-02-11
Publication Title Journal of Clinical Medicine
Volume volume15
Issue issue4
Publisher MDPI AG
Start Page 1422
ISSN 2077-0383
Content Type Journal Article
language English
OAI-PMH Set 岡山大学
Copyright Holders © 2026 by the authors.
File Version publisher
DOI 10.3390/jcm15041422
Related Url isVersionOf https://doi.org/10.3390/jcm15041422
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Author Yamase, Yuko| Takebe, Katsuki| Horie, Kengo| Mitoh, Yoshihiro| Yamashita, Atsuko| Yoshida, Ryusuke|
Keywords Taste detection Organic acid preference G-protein coupled receptor (GPCR) Knockout mice Surface electrostatic potential
Published Date 2026-02
Publication Title Journal of Oral Biosciences
Volume volume68
Issue issue1
Publisher Elsevier BV
Start Page 100731
ISSN 1349-0079
NCID AA11896386
Content Type Journal Article
language English
OAI-PMH Set 岡山大学
Copyright Holders © 2026 Japanese Association for Oral Biology.
File Version publisher
DOI 10.1016/j.job.2025.100731
Web of Science KeyUT 001663463100001
Related Url isVersionOf https://doi.org/10.1016/j.job.2025.100731
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Author Yoshihara, Kumiko| Nagaoka, Noriyuki| Lee, Sungho| Maruo, Yukinori| Spirrett, Fiona| Kirihara, Soshu| Yoshida, Yasuhiro| Van Meerbeek, Bart|
Keywords additive manufacturing bond strength dental crown dental resin cement dental zirconia
Published Date 2026-01-31
Publication Title Materials
Volume volume19
Issue issue3
Publisher MDPI AG
Start Page 563
ISSN 1996-1944
Content Type Journal Article
language English
OAI-PMH Set 岡山大学
Copyright Holders © 2026 by the authors.
File Version publisher
DOI 10.3390/ma19030563
Related Url isVersionOf https://doi.org/10.3390/ma19030563
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Author Tsuruta, Takeshi| Wakisaka, Mami| Watanabe, Takumi| Nishijima, Aoi| Ikeda, Akihito| Teraoka, Mao| Wang, Tianyang| Chen, Kuiyi| Nishino, Naoki|
Keywords aging aminopeptidase N bone metabolism lactic acid bacteria small intestine
Published Date 2025-06-15
Publication Title International Journal of Molecular Sciences
Volume volume26
Issue issue12
Publisher MDPI AG
Start Page 5742
ISSN 1422-0067
Content Type Journal Article
language English
OAI-PMH Set 岡山大学
Copyright Holders © 2025 by the authors.
File Version publisher
PubMed ID 40565206
DOI 10.3390/ijms26125742
Web of Science KeyUT 001515973900001
Related Url isVersionOf https://doi.org/10.3390/ijms26125742
FullText URL fulltext20260205-01.pdf
Author Hanaya, Tadashi| Yamamoto, Hiroshi|
Keywords pteridine pterin glycoside biopterin ciliapterin neopterin limipterin tepidopterin asperopterin-A protecting group glycosylation
Note This is the peer reviewed version of the following article: Hanaya, T. and Yamamoto, H. (2013), Synthesis of biopterin and related pterin glycosides. IUBMB Life, 65: 300-309. https://doi.org/10.1002/iub.1137, which has been published in final form at https://doi.org/10.1002/iub.1137. This article may be used for non-commercial purposes in accordance with Wiley Terms and Conditions for Use of Self-Archived Versions. This article may not be enhanced, enriched or otherwise transformed into a derivative work, without express permission from Wiley or by statutory rights under applicable legislation. Copyright notices must not be removed, obscured or modified. The article must be linked to Wiley’s version of record on Wiley Online Library and any embedding, framing or otherwise making available the article or pages thereof by third parties from platforms, services and websites other than Wiley Online Library must be prohibited.|
Published Date 2013-02-22
Publication Title IUBMB Life
Volume volume65
Issue issue4
Publisher Wiley
Start Page 300
End Page 309
ISSN 1521-6543
NCID AA11380907
Content Type Journal Article
language English
OAI-PMH Set 岡山大学
Copyright Holders © 2013 International Union of Biochemistry and Molecular Biology, Inc.
File Version author
PubMed ID 23436386
DOI 10.1002/iub.1137
Web of Science KeyUT 000316570600002
Related Url isVersionOf https://doi.org/10.1002/iub.1137
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Author Fujii, Keiko| Kitamura, Wataru| Washio, Kana| Ikeuchi, Kazuhiro| Shimono, Joji| Murakami, Hiroyuki| Otsuka, Fumio| Maeda, Yoshinobu| Fujii, Nobuharu|
Keywords acid citrate dextrose solution autologous continuous mononuclear cell collection highly concentrated sodium pediatric peripheral blood stem cells
Published Date 2026-02-02
Publication Title Transfusion
Publisher Wiley
ISSN 0041-1132
NCID AA00868753
Content Type Journal Article
language English
OAI-PMH Set 岡山大学
Copyright Holders © 2026 The Author(s).
File Version publisher
PubMed ID 41630350
DOI 10.1111/trf.70102
Related Url isVersionOf https://doi.org/10.1111/trf.70102
Author Hanaya, Tadashi| Maeda, Yuta| Iwasaki, Katsuya|
Keywords microcystbiopterin B pteridine pterin glycoside structural identification
Note This is the peer reviewed version of the following article: T. Hanaya, Y. Maeda, and K. Iwasaki, “ An Improved Synthesis of a Key Intermediate for Glycosylation of Biopterin and Its Application for the First Synthesis of Microcystbiopterin B,” Journal of Heterocyclic Chemistry 62, no. 12 (2025): 2021–2029, https://doi.org/10.1002/jhet.70124, which has been published in final form at https://doi.org/10.1002/jhet.70124. This article may be used for non-commercial purposes in accordance with Wiley Terms and Conditions for Use of Self-Archived Versions. This article may not be enhanced, enriched or otherwise transformed into a derivative work, without express permission from Wiley or by statutory rights under applicable legislation. Copyright notices must not be removed, obscured or modified. The article must be linked to Wiley’s version of record on Wiley Online Library and any embedding, framing or otherwise making available the article or pages thereof by third parties from platforms, services and websites other than Wiley Online Library must be prohibited.| This fulltext file will be available in Oct. 2026.|
Published Date 2025-10
Publication Title Journal of Heterocyclic Chemistry
Volume volume62
Issue issue12
Publisher Wiley
Start Page 2021
End Page 2029
ISSN 0022-152X
NCID AA00699237
Content Type Journal Article
language English
OAI-PMH Set 岡山大学
Copyright Holders © 2025 Wiley Periodicals LLC.
File Version author
DOI 10.1002/jhet.70124
Web of Science KeyUT 001585178600001
Related Url isVersionOf https://doi.org/10.1002/jhet.70124
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Author Matsumoto, Toshiki| Nakamura, Shin| Ito‐Shinoda, Yuki| Sakamoto, Mai| Ishii, Takayuki| Nonomura, Yasuki| Ideguchi, Hidetaka| Okubo, Keisuke| Takeuchi‐Hatanaka, Kazu| Omori, Kazuhiro| Yamamoto, Tadashi| Takashiba, Shogo|
Keywords autologous bone graft fibroblast growth factor-2 periodontal pocket periodontal regeneration periodontitis vertical bone defect
Published Date 2026-01-19
Publication Title Journal of Periodontology
Publisher Wiley
ISSN 0022-3492
NCID AA00704406
Content Type Journal Article
language English
OAI-PMH Set 岡山大学
Copyright Holders © 2026 The Author(s).
File Version publisher
PubMed ID 41553860
DOI 10.1002/jper.70060
Web of Science KeyUT 001664142500001
Related Url isVersionOf https://doi.org/10.1002/jper.70060
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Author Okamoto, Soichiro| Matsui, Yusuke| Tomita, Koji| Munetomo, Kazuaki| Umakoshi, Noriyuki| Mitsuhashi, Toshiharu| Iguchi, Toshihiro| Hiraki, Takao|
Keywords pneumothorax lung biopsy image-guided biopsy needle tract sealing
Published Date 2025-12-29
Publication Title Interventional Radiology
Volume volume10
Publisher The Japanese Society of Interventional Radiology
Start Page e2025-0068
ISSN 2432-0935
Content Type Journal Article
language English
OAI-PMH Set 岡山大学
Copyright Holders © 2025 Japanese Society of Interventional Radiology
File Version publisher
DOI 10.22575/interventionalradiology.2025-0068
Web of Science KeyUT 001652148600005
Related Url isVersionOf https://doi.org/10.22575/interventionalradiology.2025-0068
Author Kajita, Shiho| Hagiya, Hideharu| Okita, Atsushi| Haruki, Yuto| Yamada, Haruto| Inoue, Yasurou| Higashionna, Tsukasa| Satou, Kana| Torigoe, Fumihiro| Iwamoto, Shinobu| Yoshida, Mika| Yamane, Yumiko| Kenmotsu, Hiroki| Sugimura, Satoru| Fujiwara, Yutaka| Ikeda, Fusao| Koyama, Toshihiro| Yoshida, Chikamasa| Andou, Shinichirou| Suwaki, Toshimitsu|
Keywords Antimicrobial resistance Antimicrobial stewardship Full-time equivalent Infection prevention and control Trend analysis
Note © 2025 Japanese Society of Chemotherapy, Japanese Association for Infectious Diseases, and Japanese Society for Infection Prevention and Control. This manuscript version is made available under the CC-BY-NC-ND 4.0 license https://creativecommons.org/licenses/by-nc-nd/4.0/| This fulltext file will be available in May 2026.|
Published Date 2025-07
Publication Title Journal of Infection and Chemotherapy
Volume volume31
Issue issue7
Publisher Elsevier BV
Start Page 102730
ISSN 1341-321X
NCID AA11057978
Content Type Journal Article
language English
OAI-PMH Set 岡山大学
Copyright Holders © 2025 Japanese Society of Chemotherapy, Japanese Association for Infectious Diseases, and Japanese Society for Infection Prevention and Control.
File Version author
PubMed ID 40373974
DOI 10.1016/j.jiac.2025.102730
Web of Science KeyUT 001499520800001
Related Url isVersionOf https://doi.org/10.1016/j.jiac.2025.102730
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Author Sadahira, Takuya| Sugihara, Masahiro| Mitsui, Yosuke| Watanabe, Toyohiko| Araki, Motoo| Watanabe, Masami|
Keywords bladder trigone botulinum toxin endoscopic topical application new drug delivery systems refractory overactive bladder
Published Date 2026-01-09
Publication Title Cureus
Volume volume18
Issue issue1
Publisher Springer Science and Business Media LLC
Start Page e101143
ISSN 2168-8184
Content Type Journal Article
language English
OAI-PMH Set 岡山大学
Copyright Holders © Copyright 2026 Sadahira et al.
File Version publisher
DOI 10.7759/cureus.101143
Related Url isVersionOf https://doi.org/10.7759/cureus.101143
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Author Sugimoto, Koki| Nishiguchi, Hideto| Hosomi, Ryota| Tanizaki, Toshifumi| Tsushima, Tadahiro| Baba, Naomichi| Misawa, Yoshihisa| Wang, Ziyi| Ono, Mitsuaki| Murakami, Yuki| Kanda, Seiji| Fukunaga, Kenji|
Keywords n-1 polyunsaturated fatty acids hexadecatetraenoic acid octadecatetraenoic acid HepG2
Published Date 2025
Publication Title Journal of Oleo Science
Volume volume74
Issue issue11
Publisher Japan Oil Chemists' Society
Start Page 1023
End Page 1032
ISSN 1345-8957
NCID AA11503337
Content Type Journal Article
language English
OAI-PMH Set 岡山大学
Copyright Holders © 2025 by Japan Oil Chemists' Society
File Version publisher
PubMed ID 41183904
DOI 10.5650/jos.ess25120
CRID 1390024725206428544
Web of Science KeyUT 001638722200006
Related Url isVersionOf https://doi.org/
Author Fukushima, Shinnosuke| Sano, Takayuki| Kashimoto, Takashige| Hagiya, Hideharu|
Keywords Pseudomonas aeruginosa Catheter-associated urinary tract infection Prostatic abscess Type III secretion system
Note © 2025 Japanese Society of Chemotherapy, Japanese Association for Infectious Diseases, and Japanese Society for Infection Prevention and Control. This manuscript version is made available under the CC-BY-NC-ND 4.0 license https://creativecommons.org/licenses/by-nc-nd/4.0/| This fulltext file will be available in Nov. 2026.|
Published Date 2025-12
Publication Title Journal of Infection and Chemotherapy
Volume volume31
Issue issue12
Publisher Elsevier BV
Start Page 102853
ISSN 1341-321X
NCID AA11057978
Content Type Journal Article
language English
OAI-PMH Set 岡山大学
Copyright Holders © 2025 Japanese Society of Chemotherapy, Japanese Association for Infectious Diseases, and Japanese Society for Infection Prevention and Control.
File Version author
PubMed ID 41224175
DOI 10.1016/j.jiac.2025.102853
Web of Science KeyUT 001620607800001
Related Url isVersionOf https://doi.org/10.1016/j.jiac.2025.102853
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Author Hashimoto, Masashi| Noma, Kazuhiro| Takeda, Yasushige| Matsumoto, Hijiri| Kawasaki, Kento| Kunitomo, Tomoyoshi| Maeda, Naoaki| Tanabe, Shunsuke| Fujiwara, Toshiyoshi|
Keywords 112aoP esophageal cancer thoracic posterior para-aortic lymph node
Published Date 2025-01
Publication Title Asian Journal of Endoscopic Surgery
Volume volume18
Issue issue1
Publisher Wiley
Start Page e70066
ISSN 1758-5902
NCID AA12488501
Content Type Journal Article
language English
OAI-PMH Set 岡山大学
Copyright Holders © 2025 The Author(s).
File Version publisher
PubMed ID 40269550
DOI 10.1111/ases.70066
Web of Science KeyUT 001473127600001
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Author Nakayama, Yuko| Ino, Aya| Yamamoto, Kazuhiro| Takara, Kohji|
Keywords axitinib renal cell carcinoma drug resistance ABC transporter
Published Date 2025-09-22
Publication Title Molecular and Clinical Oncology
Volume volume23
Issue issue5
Publisher Spandidos Publications
Start Page 101
ISSN 2049-9450
Content Type Journal Article
language English
OAI-PMH Set 岡山大学
Copyright Holders © Nakayama et al.
File Version publisher
PubMed ID 41089665
DOI 10.3892/mco.2025.2896
Web of Science KeyUT 001592033400001
Related Url isVersionOf https://doi.org/10.3892/mco.2025.2896