result 1530 件
| Author | Mizuki, Yutaka| Takaki, Manabu| Okahisa, Yuko| Sakamoto, Shinji| Kodama, Masafumi| Ujike, Hiroshi| Uchitomi, Yosuke| |
|---|---|
| Published Date | 2014-11 |
| Publication Title | Human Psychopharmacology: Clinical and Experimental |
| Volume | volume29 |
| Issue | issue6 |
| Content Type | Journal Article |
| FullText URL | K0005071_abstract_review.pdf K0005071_fulltext.pdf |
|---|---|
| Author | Onoda, Akihisa| |
| Published Date | 2014-12-31 |
| Content Type | Thesis or Dissertation |
| Grant Number | 甲第5071号 |
| Granted Date | 2014-12-31 |
| Thesis Type | Doctor of Philosophy in Medical Science |
| Grantor | 岡山大学 |
| language | Japanese English |
| FullText URL | K0005067_abstract_review.pdf K0005067_fulltext.pdf |
|---|---|
| Author | Mizuki, Yutaka| |
| Published Date | 2014-12-31 |
| Content Type | Thesis or Dissertation |
| Grant Number | 甲第5067号 |
| Granted Date | 2014-12-31 |
| Thesis Type | Doctor of Philosophy in Medical Science |
| Grantor | 岡山大学 |
| language | Japanese |
| Author | Kamae, Yuichi| Uryu, Outa| Miki, Taiki| Tomioka, Kenji| |
|---|---|
| Published Date | 2014-12-11 |
| Publication Title | PLoS ONE |
| Volume | volume9 |
| Issue | issue12 |
| Content Type | Journal Article |
| JaLCDOI | 10.18926/AMO/53028 |
|---|---|
| FullText URL | 68_6_379.pdf |
| Author | Doi, Shinichiro| Kimura, Shuhei| Morizane, Yuki| Hosogi, Mika| Hosokawa, Mio| Shiode, Yusuke| Kawata, Tetsuhiro| Kondo, Eisei| Shiraga, Fumio| |
| Abstract | We report a case of POEMS syndrome in a 20-year-old patient diagnosed after visiting an eye clinic with a chief complaint of reduced visual acuity. A male university student aged 20 years was referred to our department complaining of blurred vision in both eyes that had persisted for 1 month. He also noted headache, nausea, and paresthesia in the lower extremities around the same time. The visual acuity of his right and left eye was 20/40 and 20/20, respectively. Optic disc edema and serous retinal detachment were present. Brain magnetic resonance imaging showed no intracranial abnormalities, while elevated cerebrospinal fluid pressure, reduced nerve conduction velocity in both lower extremities, hepatosplenomegaly, M proteinemia, high blood VEGF levels, osteoblastic and osteolytic changes in the spine, and atypical plasma cells in bone lesions were noted. From the above findings, the patient was diagnosed with POEMS syndrome. He received high-dose dexamethasone, thalidomide, and radiotherapy on the sacral mass, followed by high-dose melphalan with autologous stem-cell support, and showed subsequent systemic and ophthalmologic improvement. Here, we report the youngest case ever of POEMS syndrome with ocular manifestation. If patients have optic disc edema in both eyes with no intracranial space-occupying lesion, POEMS syndrome should be considered in differential diagnosis, regardless of age. |
| Keywords | POEMS syndrome serous retinal detachment VEGF |
| Amo Type | Case Report |
| Publication Title | Acta Medica Okayama |
| Published Date | 2014-12 |
| Volume | volume68 |
| Issue | issue6 |
| Publisher | Okayama University Medical School |
| Start Page | 379 |
| End Page | 383 |
| ISSN | 0386-300X |
| NCID | AA00508441 |
| Content Type | Journal Article |
| language | English |
| Copyright Holders | CopyrightⒸ 2014 by Okayama University Medical School |
| File Version | publisher |
| Refereed | True |
| PubMed ID | 25519033 |
| Web of Science KeyUT | 000346882200009 |
| JaLCDOI | 10.18926/AMO/53020 |
|---|---|
| FullText URL | 68_6_317.pdf |
| Author | Kasahara, Kyosuke| Miyoshi, Ko| Murakami, Shinki| Miyazaki, Ikuko| Asanuma, Masato| |
| Abstract | In vertebrates, almost all somatic cells extend a single immotile cilium, referred to as a primary cilium. Increasing evidence suggests that primary cilia serve as cellular antennae in many types of tissues by sensing chemical or mechanical stimuli in the milieu surrounding the cells. In rodents an antibody to adenylyl cyclase 3 (AC3) has been widely used to label the primary cilia of neurons in vivo by immunostaining, whereas the lack of markers for the primary cilia of astrocytes has made it difficult to observe astrocytic primary cilia in vivo. Here, we obtained a visualization of astrocytic primary cilia in the mouse brain. In the somatosensory cortex, a large portion of neurons and astrocytes at postnatal day 10 (P10), and of neurons at P56 had AC3-positive primary cilia, whereas only approx. one-half of the astrocytes in the P56 mice carried primary cilia weakly positive for AC3. In contrast, the majority of astrocytes had ADP-ribosylation factor-like protein 13B (Arl13b)-positive primary cilia in the somatosensory cortex and other brain regions of P56 mice. The lengths of astrocytic primary cilia positive for Arl13b varied among the brain regions. Our data indicate that Arl13b is a noteworthy marker of astrocytic primary cilia in the brain. |
| Keywords | primary cilia astrocyte ADP-ribosylation factor-like protein 13B |
| Amo Type | Original Article |
| Publication Title | Acta Medica Okayama |
| Published Date | 2014-12 |
| Volume | volume68 |
| Issue | issue6 |
| Publisher | Okayama University Medical School |
| Start Page | 317 |
| End Page | 322 |
| ISSN | 0386-300X |
| NCID | AA00508441 |
| Content Type | Journal Article |
| language | English |
| Copyright Holders | CopyrightⒸ 2014 by Okayama University Medical School |
| File Version | publisher |
| Refereed | True |
| PubMed ID | 25519025 |
| Web of Science KeyUT | 000346882200001 |
| FullText URL | Bri_Jou_Der_171_3_492-498.pdf |
|---|---|
| Author | Takiguchi, T| Morizane, S| Yamamoto, T| Kajita, A| Ikeda, K| Iwatsuki, K| |
| Note | This is the accepted version of the following article: FULLCITE, which has been published in final form at http://dx.doi.org/10.1111/bjd.12942| 学位審査副論文| |
| Published Date | 2014-09 |
| Publication Title | British Journal of Dermatology |
| Volume | volume171 |
| Issue | issue3 |
| Start Page | 492 |
| End Page | 498 |
| ISSN | 0007-0963 |
| Content Type | Journal Article |
| language | English |
| OAI-PMH Set | 岡山大学 |
| Copyright Holders | © 2014 British Association of Dermatologists |
| File Version | author |
| PubMed ID | 24601852 |
| DOI | 10.1111/bjd.12942 |
| Web of Science KeyUT | 000344006900186 |
| Related Url | http://ousar.lib.okayama-u.ac.jp/metadata/52974 http://ousar.lib.okayama-u.ac.jp/53764 |
| Author | Alamusi| Matsuo, Toshihiko| Hosoya, Osamu| Tsutsui, Kimiko M.| Uchida, Tetsuya| |
|---|---|
| Published Date | 2013-09 |
| Publication Title | Journal of Artificial Organs |
| Volume | volume16 |
| Issue | issue3 |
| Content Type | Journal Article |
| Author | Tsuji, Kenji| Kitamura, Shinji| Makino, Hirofumi| |
|---|---|
| Published Date | 2014-04-25 |
| Publication Title | Biochemical and Biophysical Research Communications |
| Volume | volume447 |
| Issue | issue1 |
| Content Type | Journal Article |
| Author | Murakami, Shinki| Miyazaki, Ikuko| Sogawa, Norio| Miyoshi, Ko| Asanuma, Masato| |
|---|---|
| Published Date | 2014-10 |
| Publication Title | Neurotoxicity Research |
| Volume | volume26 |
| Issue | issue3 |
| Content Type | Journal Article |
| Author | Tomotsuka, Naoto| Kaku, Ryuji| Obata, Norihiko| Matsuoka, Yoshikazu| Kanzaki, Hirotaka| Taniguchi, Arata| Muto, Noriko| Omiya, Hiroki| Itano, Yoshitaro| Sato, Tadasu| Ichikawa, Hiroyuki| Mizobuchi, Satoshi| Morimatsu, Hiroshi| |
|---|---|
| Published Date | 2014-07-11 |
| Publication Title | Journal of Pain Research |
| Volume | volume7 |
| Content Type | Journal Article |
| FullText URL | O0004431_abstract_review.pdf O0004431_fulltext.pdf |
|---|---|
| Author | Vu Van Hai| |
| Published Date | 2014-09-30 |
| Content Type | Thesis or Dissertation |
| Grant Number | 乙第4431号 |
| Granted Date | 2014-09-30 |
| Thesis Type | Doctor of Philosophy in Agriculture |
| Grantor | 岡山大学 |
| language | Japanese English |
| FullText URL | K0005056_abstract_review.pdf K0005056_fulltext.pdf |
|---|---|
| Author | 文学| |
| Published Date | 2014-09-30 |
| Content Type | Thesis or Dissertation |
| Grant Number | 甲第5056号 |
| Granted Date | 2014-09-30 |
| Thesis Type | Doctor of Philosophy in Agriculture |
| Grantor | 岡山大学 |
| language | Japanese |
| FullText URL | K0005050_abstract_review.pdf K0005050_fulltext.pdf |
|---|---|
| Author | Samah Ibrahim Mohamed EL-Ghlban| |
| Published Date | 2014-09-30 |
| Content Type | Thesis or Dissertation |
| Grant Number | 甲第5050号 |
| Granted Date | 2014-09-30 |
| Thesis Type | Doctor of Philosophy in Engineering |
| Grantor | 岡山大学 |
| language | Japanese English |
| FullText URL | K0005049_abstract_review.pdf K0005049_fulltext.pdf |
|---|---|
| Author | 閻 | |
| Published Date | 2014-09-30 |
| Content Type | Thesis or Dissertation |
| Grant Number | 甲第5049号 |
| Granted Date | 2014-09-30 |
| Thesis Type | Doctor of Philosophy in Engineering |
| Grantor | 岡山大学 |
| language | Japanese English |
| FullText URL | K0005047_abstract_review.pdf K0005047_fulltext.pdf |
|---|---|
| Author | 李 玉傑| |
| Published Date | 2014-09-30 |
| Content Type | Thesis or Dissertation |
| Grant Number | 甲第5047号 |
| Granted Date | 2014-09-30 |
| Thesis Type | Doctor of Philosophy in Engineering |
| Grantor | 岡山大学 |
| language | Japanese English |
| FullText URL | K0005046_abstract_review.pdf K0005046_fulltext.pdf |
|---|---|
| Author | 楊 偉平| |
| Published Date | 2014-09-30 |
| Content Type | Thesis or Dissertation |
| Grant Number | 甲第5046号 |
| Granted Date | 2014-09-30 |
| Thesis Type | Doctor of Philosophy in Engineering |
| Grantor | 岡山大学 |
| language | Japanese English |
| FullText URL | K0005040_abstract_review.pdf K005040_fulltext.pdf |
|---|---|
| Author | Takiguchi, Tetsuya| |
| Published Date | 2014-09-30 |
| Content Type | Thesis or Dissertation |
| Grant Number | 甲第5040号 |
| Granted Date | 2014-09-30 |
| Thesis Type | Doctor of Philosophy in Medical Science |
| Grantor | 岡山大学 |
| language | Japanese English |
| FullText URL | K0005034_abstract_review.pdf K0005034_fulltext.pdf |
|---|---|
| Author | 阿拉木斯| |
| Published Date | 2014-09-30 |
| Content Type | Thesis or Dissertation |
| Grant Number | 甲第5034号 |
| Granted Date | 2014-09-30 |
| Thesis Type | Doctor of Philosophy in Medical Science |
| Grantor | 岡山大学 |
| language | Japanese English |
| FullText URL | K0005032_abstract_review.pdf K0005032_fulltext.pdf |
|---|---|
| Author | Tsuji, Kenji| |
| Published Date | 2014-09-30 |
| Content Type | Thesis or Dissertation |
| Grant Number | 甲第5032号 |
| Granted Date | 2014-09-30 |
| Thesis Type | Doctor of Philosophy in Medical Science |
| Grantor | 岡山大学 |
| language | Japanese English |
