result 8481 件
| FullText URL | K0006882_abstract_review.pdf K0006882_fulltext.pdf |
|---|---|
| Author | GAO, TONG| |
| Published Date | 2023-09-25 |
| Content Type | Thesis or Dissertation |
| Grant Number | 甲第6882号 |
| Granted Date | 2023-09-25 |
| Thesis Type | Doctor of Philosophy in Medical Science |
| Grantor | 岡山大学 |
| language | English |
| Copyright Holders | © 2023 by the authors. |
| FullText URL | K0006881_abstract_review.pdf K0006881_fulltext.pdf |
|---|---|
| Author | SATO, Yoshihiro| |
| Published Date | 2023-09-25 |
| Content Type | Thesis or Dissertation |
| Grant Number | 甲第6881号 |
| Granted Date | 2023-09-25 |
| Thesis Type | Doctor of Philosophy in Medical Science |
| Grantor | 岡山大学 |
| language | English |
| Copyright Holders | © 2023 by the authors. |
| FullText URL | K0006880_abstract_review.pdf K0006880_fulltext.pdf K0006880_summary.pdf |
|---|---|
| Author | SHIKATANI, Yoshinobu| |
| Published Date | 2023-09-25 |
| Content Type | Thesis or Dissertation |
| Grant Number | 甲第6880号 |
| Granted Date | 2023-09-25 |
| Thesis Type | Doctor of Philosophy in Medical Science |
| Grantor | 岡山大学 |
| language | English |
| Copyright Holders | © Springer Nature Singapore Pte Ltd. 2020 |
| FullText URL | K0006879_abstract_review.pdf K0006879_fulltext.pdf |
|---|---|
| Author | SUMII, Yuichi| |
| Published Date | 2023-09-25 |
| Content Type | Thesis or Dissertation |
| Grant Number | 甲第6879号 |
| Granted Date | 2023-09-25 |
| Thesis Type | Doctor of Philosophy in Medical Science |
| Grantor | 岡山大学 |
| language | English |
| Copyright Holders | © 2023, Sumii et al. |
| FullText URL | fulltext.pdf |
|---|---|
| Author | Sang, Yizhen| Tsuji, Kenji| Nakanoh, Hiroyuki| Fukushima, Kazuhiko| Kitamura, Shinji| Wada, Jun| |
| Keywords | semaphorin 3A neuropilin-1 podocyte diabetic nephropathy acute kidney injury chronic kidney injury lupus nephritis fibrosis apoptosis inflammation |
| Published Date | 2023-09-25 |
| Publication Title | Diagnostics |
| Volume | volume13 |
| Issue | issue19 |
| Publisher | MDPI |
| Start Page | 3038 |
| ISSN | 2075-4418 |
| Content Type | Journal Article |
| language | English |
| OAI-PMH Set | 岡山大学 |
| Copyright Holders | © 2023 by the authors. |
| File Version | publisher |
| PubMed ID | 37835781 |
| DOI | 10.3390/diagnostics13193038 |
| Web of Science KeyUT | 001083705600001 |
| Related Url | isVersionOf https://doi.org/10.3390/diagnostics13193038 |
| JaLCDOI | 10.18926/AMO/65979 |
|---|---|
| FullText URL | 77_5_553.pdf |
| Author | Murokawa, Takahiro| Sakamoto, Shinya| Tabuchi, Motoyasu| Sui, Kenta| Ozaki, Kazuhide| Matsumoto, Manabu| Iwata, Jun| Okabayashi, Takehiro| Yoshida, Hiroshi| |
| Abstract | Gastric cancer with peritoneal metastases is typically a devastating diagnosis. Ligamentum teres hepatis (LTH) metastasis is an extremely rare presentation with only four known cases. Herein, we report salvage surgery of successive metastases to the abdominal wall and LTH in a patient originally presenting with advanced gastric cancer with peritoneal metastasis, leading to long-term survival. A 72-year-old man with advanced gastric cancer underwent curative-intent distal gastrectomy with D2 lymph node dissection for gastric outlet obstruction. During this procedure, three small peritoneal metastases were detected in the lesser omentum, the small mesentery, and the mesocolon; however, intraoperative abdominal lavage cytology was negative. We added cytoreductive surgery for peritoneal metastasis. The pathological diagnosis of the gastric cancer was tubular adenocarcinoma with pT4aN1pM1(PER/P1b)CY0 stage IV (Japanese classification of gastric carcinoma/JCGC 15th), or T4N1M1b stage IV (UICC 7th). Post-operative adjuvant chemotherapy with S-1 (TS-1)+cisplatin (CDDP) was administered for 8 months followed by S-1 monotherapy for 4 months. At 28 months after the initial surgery, a follow-up computed tomography (CT) detected a small mass beneath the upper abdominal wall. The ass showed mild avidity on 18F-fluorodeoxyglucose positron-emission (FDG-PET) CT. Salvage resection was performed for diagnosis and treatment, and pathological findings were consistent with primary gastric cancer metastasis. At 49 months after the initial gastrectomy, a new lesion was detected in the LTH with a similar level of avidity on FDG-PET CT as the abdominal wall metastatic lesion. We performed a second salvage surgery for the LTH tumor, which also showed pathology of gastric cancer metastasis. There has been no recurrence up to 1 year after the LTH surgery. With multidisciplinary treatment the patient has survived almost 5 years after the initial gastrectomy. Curative-intent gastrectomy with cytoreductive surgery followed by adjuvant chemotherapy for advanced gastric cancer with localized peritoneal metastasis might have had a survival benefit in our patient. Successive salvage surgeries for oligometastatic lesions in the abdominal wall and the LTH also yielded favorable outcomes. |
| Keywords | gastric cancer peritoneal metastasis ligamentum teres hepatis oligometastasis salvage surgery |
| Amo Type | Case Report |
| Publication Title | Acta Medica Okayama |
| Published Date | 2023-10 |
| Volume | volume77 |
| Issue | issue5 |
| Publisher | Okayama University Medical School |
| Start Page | 553 |
| End Page | 559 |
| ISSN | 0386-300X |
| NCID | AA00508441 |
| Content Type | Journal Article |
| language | English |
| Copyright Holders | Copyright Ⓒ 2023 by Okayama University Medical School |
| File Version | publisher |
| Refereed | True |
| PubMed ID | 37899267 |
| Web of Science KeyUT | 001110832700001 |
| JaLCDOI | 10.18926/AMO/65972 |
|---|---|
| FullText URL | 77_5_499.pdf |
| Author | Hatakeyama, Yuji| Hongo, Michio| Kido, Tadato| Urayama, Masakazu| Kasukawa, Yuji| Sasaki, Hiroshi| Aizawa, Toshiaki| Kudo, Daisuke| Kimura, Ryota| Ono, Yuichi| Kasama, Fumihito| Miyakoshi, Naohisa| |
| Abstract | This study aimed to clarify neurological differences among the epiconus, conus medullaris, and cauda equina syndromes. Eighty-seven patients who underwent surgery for acute thoracolumbar spinal injuries were assessed. We defined the epiconus as the region from the terminal end of the spinal cord to the proximal 1.0 to 2.25 vertebral bodies, the conus medullaris as the region proximal to < 1.0 vertebral bodies, and the cauda equina as the distal part of the nerve roots originating from the spinal cord. On the basis of the distance from the terminal end of the spinal cord to the narrowest level of the spinal canal, the narrowest levels were ordered as follows: the epiconus followed by the conus medullaris and cauda equina. The narrowest levels were the epiconus in 22 patients, conus medullaris in 37 patients, and cauda equina in 25 patients. On admission, significantly more patients had a narrowed epiconus of Frankel grades A-C than a narrowed cauda equina. At the final follow-up, there were no significant differences in neurological recovery among those with epiconus, conus medullaris, or cauda equina syndrome. Anatomically classifying the narrowest lesion is useful for clarifying the differences and similarities among these three syndromes. |
| Keywords | thoracolumbar spinal injury terminal end of spinal cord conus medullaris epiconus syndrome cauda equina syndrome |
| Amo Type | Original Article |
| Publication Title | Acta Medica Okayama |
| Published Date | 2023-10 |
| Volume | volume77 |
| Issue | issue5 |
| Publisher | Okayama University Medical School |
| Start Page | 499 |
| End Page | 509 |
| ISSN | 0386-300X |
| NCID | AA00508441 |
| Content Type | Journal Article |
| language | English |
| Copyright Holders | Copyright Ⓒ 2023 by Okayama University Medical School |
| File Version | publisher |
| Refereed | True |
| PubMed ID | 37899261 |
| Web of Science KeyUT | 001108661600007 |
| JaLCDOI | 10.18926/AMO/65970 |
|---|---|
| FullText URL | 77_5_479.pdf |
| Author | Murata, Akiko| Matsumoto, Naomi| Miyaji, Chikara| Takao, Soshi| Yorifuji, Takashi| |
| Abstract | For decades, the notion has persisted in developed countries that exclusive care by the mothers is best for the development of children up to 3 years of age. To examine the veracity of this “myth of the first three years” in Japan, we examined the effects of childcare facility use for children younger than 3 years on their development using the cohorts of the Longitudinal Survey of Newborns in the 21st Century conducted in Japan. Of the 47,015 respondents to the survey, we studied the children of 5,508 mothers with university/professional education to evaluate the relationships between primary early (< 2.5 years) childcare providers during weekday daytime hours and specific development indices for the ages of 2.5, 5.5, and 8 years. At the age of 2.5 and 5.5 years, children attending childcare facilities were judged as having more advanced developmental behaviors by their parents, such as being able to compose a two-word sentence (adjusted odds ratio [aOR]: 0.22) or to express emotions (aOR: 0.81), compared with those cared for by mothers. However, at the age of 8 years, children who attended childcare facilities as infants < 2.5 years showed more aggressive behavior in interrupting people (aOR: 1.20) and causing disturbances in public (aOR: 1.26) than those cared for by mothers (after adjustment for numerous child and parental factors). Although these results are generally consistent with previous studies, issues potentially involved with problem behavior such as quality of childcare require further investigation, as does the case of children of mothers with more modest educational attainment. |
| Keywords | “myth of the first three years” childcare child development problem behavior educational attainment |
| Amo Type | Original Article |
| Publication Title | Acta Medica Okayama |
| Published Date | 2023-10 |
| Volume | volume77 |
| Issue | issue5 |
| Publisher | Okayama University Medical School |
| Start Page | 479 |
| End Page | 490 |
| ISSN | 0386-300X |
| NCID | AA00508441 |
| Content Type | Journal Article |
| language | English |
| Copyright Holders | Copyright Ⓒ 2023 by Okayama University Medical School |
| File Version | publisher |
| Refereed | True |
| PubMed ID | 37899259 |
| Web of Science KeyUT | 001108661600005 |
| JaLCDOI | 10.18926/AMO/65969 |
|---|---|
| FullText URL | 77_5_471.pdf |
| Author | Oka, Shohei| Harada, Keita| Yamamoto, Shumpei| Yasutomi, Eriko| Igawa, Shoko| Ohmori, Masayasu| Hirai, Mami| Yamasaki, Yasushi| Inokuchi, Toshihiro| Kinugasa, Hideaki| Takahara, Masahiro| Hiraoka, Sakiko| Okada, Hiroyuki| |
| Abstract | Although the clinical usefulness of colonoscopy has been established, the procedure remains painful for many patients. This study was designed to clarify the factors predicting colonoscopy-related pain. We evaluated 283 consecutive patients who completed a first-ever, total colonoscopy without sedatives or analgesics. The severity of pain symptoms was evaluated by a numeric rating scale (NRS) in a questionnaire immediately after the colonoscopy. Patient backgrounds and endoscopic findings were analyzed to evaluate their association with pain. Out of 283 patients, 53 scored their pain 0-1 on the NRS while 48 scored it 6-10. We defined the colonoscopies of the former and latter patients as painless and painful, respectively, and compared the two. Multivariate analyses revealed that low body weight (OR 4.95, 95%CI 1.89-12.99) and longer intubation time (OR 3.63, 95%CI 1.46-9.03) were significant risk factors for painful colonoscopy. To identify factors contributing to the increased intubation time, we divided subjects into short- and long-intubation-time groups based on a median insertion time of 7 min. Older age (OR 2.28, 95%CI 1.31-3.98), previous abdominal surgery (OR 1.93, 95%CI 1.13-3.32) and findings of invasive cancer (OR 10.90, 95%CI 1.34-88.90) were significant factors for longer intubation time. |
| Keywords | colonoscopy colonoscopy-related pain comfortable colonoscopy |
| Amo Type | Original Article |
| Publication Title | Acta Medica Okayama |
| Published Date | 2023-10 |
| Volume | volume77 |
| Issue | issue5 |
| Publisher | Okayama University Medical School |
| Start Page | 471 |
| End Page | 478 |
| ISSN | 0386-300X |
| NCID | AA00508441 |
| Content Type | Journal Article |
| language | English |
| Copyright Holders | Copyright Ⓒ 2023 by Okayama University Medical School |
| File Version | publisher |
| Refereed | True |
| PubMed ID | 37899258 |
| Web of Science KeyUT | 001108661600004 |
| JaLCDOI | 10.18926/AMO/65968 |
|---|---|
| FullText URL | 77_5_461.pdf |
| Author | Homma, Daisuke| Minato, Izumi| Imai, Norio| Miyasaka, Dai| Sakai, Yoshinori| Horigome, Yoji| Suzuki, Hayato| Dohmae, Yoichiro| Endo, Naoto| |
| Abstract | This study aimed to determine which muscle the gluteus maximus, gluteus medius, gluteus minimus (Gmin), or tensor fasciae latae (TFL) contributes most to hip abduction strength and to identify effective sites for cross-sectional area (CSA) Gmin and TFL measurement in hip osteoarthritis (OAhip) patients. Twenty-eight patients with OAhip were included. The muscle CSA and volume were determined using magnetic resonance imaging. Peak isometric strength was determined using hand-held dynamometry. Muscle volumes were normalized to the total muscle volume of hip abductors. Multiple regression analysis was performed. The difference between the CSA of Gmin and TFL was calculated, and correlations with volume and muscle strength were determined. Gmin volume was related to abductor muscle strength (p=0.042). The peak CSA of the Gmin correlated with muscle volume and strength. The CSA of the TFL correlated with volume, with no difference between the CSA of the most protruding part of the lesser trochanter and peak CSA. Gmin volume was strongly related to abductor muscle strength. Peak CSA is a useful parameter for assessing the CSA of the Gmin among patients with OAhip. The CSA of the TFL should be measured at the most protruding part of the lesser trochanter. |
| Keywords | gluteus minimus tensor fasciae latae cross-sectional area muscle volume hip osteoarthritis |
| Amo Type | Original Article |
| Publication Title | Acta Medica Okayama |
| Published Date | 2023-10 |
| Volume | volume77 |
| Issue | issue5 |
| Publisher | Okayama University Medical School |
| Start Page | 461 |
| End Page | 469 |
| ISSN | 0386-300X |
| NCID | AA00508441 |
| Content Type | Journal Article |
| language | English |
| Copyright Holders | Copyright Ⓒ 2023 by Okayama University Medical School |
| File Version | publisher |
| Refereed | True |
| PubMed ID | 37899257 |
| Web of Science KeyUT | 001108661600003 |
| JaLCDOI | 10.18926/AMO/65966 |
|---|---|
| FullText URL | 77_5_443.pdf |
| Author | Miyaji, Chikara| Takao, Soshi| Habu, Hiroshi| Matsumoto, Naomi| Aoo, Ken| Nishita, Yosuke| Tsuri, Masao| Yorifuji, Takashi| |
| Abstract | This study examined whether participation in an art project was associated with higher social capital (SC). We conducted a questionnaire survey from November 2021 to March 2022 among residents aged 20 years or older of Naoshima, an island in Kagawa Prefecture, Japan. Before the survey, the Setouchi Triennale had been held on Naoshima four times, starting in 2010. We calculated propensity scores for Triennale participation and performed propensity score matching. We then compared cognitive and structural SC by Triennale participation and found significant differences, respectively. We adopted a conditional ordered logistic regression analysis with propensity score matching for cognitive or structural SC, and found adjusted odd ratios of 2.913 (95%CI, 1.846-4.596) for cognitive SC and 4.535 (95%CI, 2.839-7.244) for structural SC. Our findings suggest that Triennale participation enhanced the cognitive aspect of SC while also building structural SC. |
| Keywords | social capital art project propensity score matching |
| Amo Type | Original Article |
| Publication Title | Acta Medica Okayama |
| Published Date | 2023-10 |
| Volume | volume77 |
| Issue | issue5 |
| Publisher | Okayama University Medical School |
| Start Page | 443 |
| End Page | 449 |
| ISSN | 0386-300X |
| NCID | AA00508441 |
| Content Type | Journal Article |
| language | English |
| Copyright Holders | Copyright Ⓒ 2023 by Okayama University Medical School |
| File Version | publisher |
| Refereed | True |
| PubMed ID | 37899255 |
| Web of Science KeyUT | 001108661600001 |
| FullText URL | fulltext.pdf |
|---|---|
| Author | Akıl, Caner| Ali, Samson| Tran, Linh T.| Gaillard, Jérémie| Li, Wenfei| Hayashida, Kenichi| Hirose, Mika| Kato, Takayuki| Oshima, Atsunori| Fujishima, Kosuke| Blanchoin, Laurent| Narita, Akihiro| Robinson, Robert C.| |
| Published Date | 2022-03-25 |
| Publication Title | Science Advances |
| Volume | volume8 |
| Issue | issue12 |
| Publisher | American Association for the Advancement of Science (AAAS) |
| Start Page | eabm2225 |
| ISSN | 2375-2548 |
| Content Type | Journal Article |
| language | English |
| OAI-PMH Set | 岡山大学 |
| Copyright Holders | © 2022 The Authors |
| File Version | publisher |
| PubMed ID | 35333570 |
| DOI | 10.1126/sciadv.abm2225 |
| Web of Science KeyUT | 000800334900012 |
| Related Url | isVersionOf https://doi.org/10.1126/sciadv.abm2225 |
| FullText URL | fulltext.pdf |
|---|---|
| Author | Miyamoto, Kazuya| Matsumoto, Kazuyuki| Obata, Taisuke| Sato, Ryosuke| Matsumi, Akihiro| Morimoto, Kosaku| Ogawa, Taiji| Terasawa, Hiroyuki| Fujii, Yuki| Yamazaki, Tatsuhiro| Uchida, Daisuke| Horiguchi, Shigeru| Tsutsumi, Koichiro| Kato, Hironari| Otsuka, Motoyuki| |
| Keywords | Balloon-assisted endoscopy Propofol Diazepam Sedation |
| Note | The version of record of this article, first published in BMC Gastroenterology, is available online at Publisher’s website: http://dx.doi.org/10.1186/s12876-023-02936-8| |
| Published Date | 2023-09-04 |
| Publication Title | BMC Gastroenterology |
| Volume | volume23 |
| Issue | issue1 |
| Publisher | BMC |
| Start Page | 296 |
| ISSN | 1471-230X |
| Content Type | Journal Article |
| language | English |
| OAI-PMH Set | 岡山大学 |
| Copyright Holders | © The Author(s) 2023. |
| File Version | publisher |
| PubMed ID | 37667224 |
| DOI | 10.1186/s12876-023-02936-8 |
| Web of Science KeyUT | 001063014700002 |
| Related Url | isVersionOf https://doi.org/10.1186/s12876-023-02936-8 |
| FullText URL | fulltext.pdf |
|---|---|
| Author | Matsumoto, Kazuyuki| Ohara, Toshiaki| Fujisawa, Masayoshi| Takaki, Akinobu| Takahara, Masahiro| Kato, Hironari| Yoshida, Ryuichi| Umeda, Yuzo| Yagi, Takahito| Matsukawa, Akihiro| Okada, Hiroyuki| |
| Keywords | Programmed death ligand 1 Bile tract neoplasm Biopsy specimen Immunohistochemistry |
| Note | The version of record of this article, first published in Journal of Gastrointestinal Surgery, is available online at Publisher’s website: http://dx.doi.org/10.1007/s11605-021-05197-6| |
| Published Date | 2022-02-08 |
| Publication Title | Journal of Gastrointestinal Surgery |
| Volume | volume26 |
| Issue | issue6 |
| Publisher | Springer Science and Business Media LLC |
| Start Page | 1213 |
| End Page | 1223 |
| ISSN | 1091-255X |
| NCID | AA11494553 |
| Content Type | Journal Article |
| language | English |
| OAI-PMH Set | 岡山大学 |
| Copyright Holders | © The Author(s) 2022 |
| File Version | publisher |
| PubMed ID | 35137343 |
| DOI | 10.1007/s11605-021-05197-6 |
| Web of Science KeyUT | 000752761400001 |
| Related Url | isVersionOf https://doi.org/10.1007/s11605-021-05197-6 |
| FullText URL | fulltext.pdf |
|---|---|
| Author | Harada, M.| |
| Note | システム処理の都合により筆頭著者のみ著者登録、その他の著者については以下の通り。 K. Abe2,3, C. Bronner2 , Y. Hayato2,3 , K. Hiraide2,3 , K. Hosokawa2 , K. Ieki2,3 , M. Ikeda2,3 , J. Kameda2,3, Y. Kanemura2, R. Kaneshima2, Y. Kashiwagi2, Y. Kataoka2,3 , S. Miki2, S. Mine2,4, M. Miura2,3, S. Moriyama2,3 , Y. Nakano2 , M. Nakahata2,3 , S. Nakayama2,3 , Y. Noguchi2 , K. Okamoto2, K. Sato2, H. Sekiya2,3 , H. Shiba2, K. Shimizu2, M. Shiozawa2,3 , Y. Sonoda2, Y. Suzuki2, A. Takeda2,3, Y. Takemoto2,3 , A. Takenaka2, H. Tanaka2,3, S. Watanabe2, T. Yano2 , S. Han5, T. Kajita3,5,6, K. Okumura3,5 , T. Tashiro5 , T. Tomiya5, X. Wang5, S. Yoshida5, G. D. Megias7, P. Fernandez8 , L. Labarga8 , N. Ospina8 , B. Zaldivar8, B. W. Pointon9,10, E. Kearns3,11, J. L. Raaf11, L. Wan11 , T. Wester11 , J. Bian4, N. J. Griskevich4 , S. Locke4, M. B. Smy3,4, H. W. Sobel3,4 , V. Takhistov4,12, A. Yankelevich4 , J. Hill13, S. H. Lee14, D. H. Moon14, R. G. Park14, B. Bodur15 , K. Scholberg3,15 , C. W. Walter3,15 , A. Beauchêne16, O. Drapier16, A. Giampaolo16, Th. A. Mueller16 , A. D. Santos16, P. Paganini16 , B. Quilain16, T. Ishizuka17, T. Nakamura18, J. S. Jang19, J. G. Learned20, K. Choi21, N. Iovine21 , S. Cao22, L. H. V. Anthony23, D. Martin23, M. Scott23 , A. A. Sztuc23, Y. Uchida23, V. Berardi24 , M. G. Catanesi24, E. Radicioni24, N. F. Calabria25 , A. Langella25 , L. N. Machado25 , G. De Rosa25, G. Collazuol26 , F. Iacob26 , M. Lamoureux26, M. Mattiazzi26 , L. Ludovici27, M. Gonin6, G. Pronost6 , C. Fujisawa28, Y. Maekawa28, Y. Nishimura28 , R. Okazaki28, R. Akutsu12, M. Friend12, T. Hasegawa12 , T. Ishida12, T. Kobayashi12, M. Jakkapu12, T. Matsubara12 , T. Nakadaira12, K. Nakamura3,12, Y. Oyama12 , K. Sakashita12, T. Sekiguchi12, T. Tsukamoto12, N. Bhuiyan29, G. T. Burton29, F. Di Lodovico29 , J. Gao29, A. Goldsack29, T. Katori29 , J. Migenda29 , Z. Xie29, S. Zsoldos3,29 , Y. Kotsar30, H. Ozaki30, A. T. Suzuki30, Y. Takagi30, Y. Takeuchi3,30 , J. Feng31, L. Feng31, J. R. Hu31 , Z. Hu31 , T. Kikawa31, M. Mori31, T. Nakaya3,31 , R. A. Wendell3,31 , K. Yasutome31, S. J. Jenkins32 , N. McCauley32 , P. Mehta32, A. Tarrant32 , Y. Fukuda33 , Y. Itow34,35 , H. Menjo34 , K. Ninomiya34, J. Lagoda36, S. M. Lakshmi36, M. Mandal36, P. Mijakowski36, Y. S. Prabhu36, J. Zalipska36, M. Jia37, J. Jiang37, C. K. Jung37, M. J. Wilking37, C. Yanagisawa37,56 , Y. Hino1 , H. Ishino1, H. Kitagawa1, Y. Koshio1,3 , F. Nakanishi1 , S. Sakai1 , T. Tada1, T. Tano1, G. Barr38, D. Barrow38 , L. Cook3,38, S. Samani38, D. Wark38,39, A. Holin40, F. Nova41 , B. S. Yang40 , J. Y. Yang40 , J. Yoo40 , J. E. P. Fannon42, L. Kneale42 , M. Malek42, J. M. McElwee42, M. D. Thiesse42 , L. F. Thompson42, S. T. Wilson42, H. Okazawa43, S. B. Kim44, E. Kwon44 , J. W. Seo44 , I. Yu44 , A. K. Ichikawa45, K. D. Nakamura45 , S. Tairafune45 , K. Nishijima46 , K. Nakagiri47, Y. Nakajima3,47 , S. Shima47, N. Taniuchi47, E. Watanabe47, M. Yokoyama3,47 , P. de Perio3 , K. Martens3, K. M. Tsui3, M. R. Vagins3,4 , J. Xia3, M. Kuze48 , S. Izumiyama48 , R. Matsumoto48 , M. Ishitsuka49, H. Ito49 , T. Kinoshita49, R. Matsumoto49, Y. Ommura49, N. Shigeta49, M. Shinoki49 , T. Suganuma49, K. Yamauchi49, J. F. Martin50, H. A. Tanaka50, T. Towstego50, R. Gaur10, V. Gousy-Leblanc10,57, M. Hartz10, A. Konaka10, X. Li10, N. W. Prouse10,51 , S. Chen51, B. D. Xu51 , B. Zhang51, M. Posiadala-Zezula52 , S. B. Boyd53, R. Edwards53, D. Hadley53, M. Nicholson53, M. O’Flaherty53, B. Richards53, A. Ali10,54, B. Jamieson54, Ll. Marti55 , A. Minamino55 , G. Pintaudi55, S. Sano55, S. Suzuki55, K. Wada55, and The Super-Kamiokande Collaboration 1 Department of Physics, Okayama University 2 Kamioka Observatory, Institute for Cosmic Ray Research, University of Tokyo 3 Kavli Institute for the Physics and Mathematics of the Universe (WPI), The University of Tokyo Institutes for Advanced Study, University of Tokyo 4 Department of Physics and Astronomy, University of California 5 Research Center for Cosmic Neutrinos, Institute for Cosmic Ray Research, University of Tokyo 6 ILANCE, CNRS - University of Tokyo International Research Laboratory 7 Institute for Cosmic Ray Research, University of Tokyo 8 Department of Theoretical Physics, University Autonoma Madrid 9 Department of Physics, British Columbia Institute of Technology 10 TRIUMF 11 Department of Physics, Boston University 12 High Energy Accelerator Research Organization (KEK) 13 Department of Physics, California State University 14 Institute for Universe and Elementary Particles, Chonnam National University 15 Department of Physics, Duke University 16 Ecole Polytechnique, IN2P3-CNRS, Laboratoire Leprince-Ringuet 17 Junior College, Fukuoka Institute of Technology 18 Department of Physics, Gifu University 19 GIST College, Gwangju Institute of Science and Technology 20 Department of Physics and Astronomy, University of Hawaii 21 Institute for Basic Science (IBS) 22 Institute For Interdisciplinary Research in Science and Education, ICISE 23 Department of Physics, Imperial College London 24 Dipartimento Interuniversitario di Fisica, INFN Sezione di Bari and Università e Politecnico di Bari 25 Dipartimento di Fisica, INFN Sezione di Napoli and Università di Napoli 26 Dipartimento di Fisica, INFN Sezione di Padova and Università di Padova 27 INFN Sezione di Roma and Università di Roma "La Sapienza," 28 Department of Physics, Keio University 29 Department of Physics, King's College London 30 Department of Physics, Kobe University, Kobe 31 Department of Physics, Kyoto University, Kyoto 32 Department of Physics, University of Liverpool 33 Department of Physics, Miyagi University of Education 34 Institute for Space-Earth Environmental Research, Nagoya University 35 Kobayashi-Maskawa Institute for the Origin of Particles and the Universe, Nagoya University 36 National Centre For Nuclear Research 37 Department of Physics and Astronomy, State University of New York at Stony Brook 38 Department of Physics, Oxford University 39 STFC, Rutherford Appleton Laboratory, Harwell Oxford, and Daresbury Laboratory 40 Department of Physics, Seoul National University 41 Rutherford Appleton Laboratory 42 Department of Physics and Astronomy, University of Sheffield 43 Department of Informatics in Social Welfare, Shizuoka University of Welfare 44 Department of Physics, Sungkyunkwan University 45 Department of Physics, Faculty of Science, Tohoku University 46 Department of Physics, Tokai University 47 Department of Physics, University of Tokyo 48 Department of Physics, Tokyo Institute of Technology 49 Department of Physics, Faculty of Science and Technology, Tokyo University of Science 50 Department of Physics, University of Toronto 51 Department of Engineering Physics, Tsinghua University 52 Faculty of Physics, University of Warsaw 53 Department of Physics, University of Warwick 54 Department of Physics, University of Winnipeg 55 Department of Physics, Yokohama National University| |
| Published Date | 2023-07-07 |
| Publication Title | Astrophysical Journal Letters |
| Volume | volume951 |
| Issue | issue2 |
| Publisher | IOP Publishing Ltd |
| Start Page | L27 |
| ISSN | 2041-8205 |
| NCID | AA00553264 |
| Content Type | Journal Article |
| language | English |
| OAI-PMH Set | 岡山大学 |
| Copyright Holders | © 2023. The Author(s). |
| File Version | publisher |
| DOI | 10.3847/2041-8213/acdc9e |
| Web of Science KeyUT | 001026263300001 |
| Related Url | isVersionOf https://doi.org/10.3847/2041-8213/acdc9e |
| FullText URL | fulltext20230828-01.pdf |
|---|---|
| Author | Furuta, Tomoyuki| Yamamoto, Toshio| Ashikari, Motoyuki| |
| Keywords | reduced-representation sequencing error correction imputation hidden Markov model |
| Published Date | 2023-03-29 |
| Publication Title | Genetics |
| Volume | volume224 |
| Issue | issue2 |
| Publisher | Oxford University Press (OUP) |
| Start Page | iyad055 |
| ISSN | 1943-2631 |
| Content Type | Journal Article |
| language | English |
| OAI-PMH Set | 岡山大学 |
| Copyright Holders | © The Author(s) 2023. |
| File Version | publisher |
| PubMed ID | 36988327 |
| DOI | 10.1093/genetics/iyad055 |
| Web of Science KeyUT | 001029662300001 |
| Related Url | isVersionOf https://doi.org/10.1093/genetics/iyad055 |
| JaLCDOI | 10.18926/AMO/65751 |
|---|---|
| FullText URL | 77_4_407.pdf |
| Author | Hotta, Kensuke| Kobayashi, Takaomi| |
| Abstract | This study aimed to investigate the usefulness of force-controlled pelvic stress radiographs in the evaluation and treatment of fragility fractures of the pelvis (FFP) using a functional treatment strategy. We conducted a retrospective study of 55 geriatric patients with FFP who underwent pelvic stress radiographs on admission. The differences in the sacral width, pelvic ring width, and medial femoral head width between the radiographs with and without the Sam Sling II M size were defined as Δ sacral width, Δ pelvic ring width, and Δ medial femoral head width, respectively. We used Pearson’s correlation test to assess the relationship between the degree of radiographic instability and the Johns Hopkins highest level of mobility scale (JH-HLM) at 10-days postadmission. Conventional receiver-operating-characteristic curve analysis was used to identify cases requiring surgery using the best cutoff value for radiographic instability. The JH-HLM was significantly correlated with Δ sacral width (r=−0.401, p=0.017), but not with Δ pelvic ring width (r=−0.298, p=0.080) nor with Δ medial femoral head width (r= −0.261, p=0.128). The best cutoff value of Δ sacral width in identifying surgical cases was 10.7 mm (sensitivity 75.0%, specificity 98.0%). Force-controlled pelvic stress radiographs could be helpful in assessing the need for surgery on admission. |
| Keywords | fragility fracture of the pelvis functional treatment strategy Sam Sling stress radiograph Johns Hopkins highest level of mobility scale |
| Amo Type | Original Article |
| Publication Title | Acta Medica Okayama |
| Published Date | 2023-08 |
| Volume | volume77 |
| Issue | issue4 |
| Publisher | Okayama University Medical School |
| Start Page | 407 |
| End Page | 414 |
| ISSN | 0386-300X |
| NCID | AA00508441 |
| Content Type | Journal Article |
| language | English |
| Copyright Holders | Copyright Ⓒ 2023 by Okayama University Medical School |
| File Version | publisher |
| Refereed | True |
| PubMed ID | 37635141 |
| Web of Science KeyUT | 001163659800001 |
| JaLCDOI | 10.18926/AMO/65750 |
|---|---|
| FullText URL | 77_4_395.pdf |
| Author | Pavlovic, Marko| Babic, Dragan| Rastovic, Pejana| Arapovic, Jurica| Martinac, Marko| Jakovac, Sanja| Barbaric, Romana| |
| Abstract | We investigated the relationship between serum tumor necrosis factor-alpha (TNF-α) levels and psychopathological symptoms, clinical and socio-demographic characteristics and antipsychotic therapy in individuals with schizophrenia. TNF-α levels were measured in 90 patients with schizophrenia and 90 healthy controls matched by age, gender, smoking status, and body mass index. The Positive and Negative Syndrome Scale (PANSS) was used to assess the severity of psychopathology in patients. No significant differences in TNF-α levels were detected between the patients and controls (p=0.736). TNF-α levels were not correlated with total, positive, negative, general, or composite PANSS scores (all p>0.05). A significant negative correlation was observed between TNF-α levels and the PANSS cognitive factor (ρ=−0.222, p=0.035). A hierarchical regression analysis identified the cognitive factor as a significant predictor of the TNF-α level (beta=−0.258, t=−2.257, p=0.027). There were no significant differences in TNF-α levels among patients treated with different types of antipsychotics (p=0.596). TNF-α levels correlated positively with the age of onset (ρ=0.233, p=0.027) and negatively with illness duration (ρ=−0.247, p=0.019) and antipsychotic treatment duration (ρ=−0.256, p=0.015). These results indicate that TNF-α may be involved in cognitive impairment in schizophrenia, and would be a potential clinical-state marker in schizophrenia. |
| Keywords | tumor necrosis factor-alpha schizophrenia psychopathology immune system |
| Amo Type | Original Article |
| Publication Title | Acta Medica Okayama |
| Published Date | 2023-08 |
| Volume | volume77 |
| Issue | issue4 |
| Publisher | Okayama University Medical School |
| Start Page | 395 |
| End Page | 405 |
| ISSN | 0386-300X |
| NCID | AA00508441 |
| Content Type | Journal Article |
| language | English |
| Copyright Holders | Copyright Ⓒ 2023 by Okayama University Medical School |
| File Version | publisher |
| Refereed | True |
| PubMed ID | 37635140 |
| Web of Science KeyUT | 001163659800010 |
| JaLCDOI | 10.18926/AMO/65749 |
|---|---|
| FullText URL | 77_4_387.pdf |
| Author | Kataoka, Takahiro| Habu, Hiroshi| Tanaka, Ayumi| Naoe, Shota| Murakami, Kaito| Fujimoto, Yuki| Yukimine, Ryohei| Takao, Soshi| Mitsunobu, Fumihiro| Yorifuji, Takashi| Yamaoka, Kiyonori| |
| Abstract | No epidemiological studies have examined the health effects of daily bathing in radon hot springs. In this cross-sectional study, we investigated the associations between radon hot spring bathing and health conditions. The target population was 5,250 adults ≥ 20 years old in the town of Misasa, Japan. We collected information about the participants’ bathing habits and alleviation of a variety of disease symptoms, and their self-rated health (SRH). Unadjusted and adjusted odds ratios (ORs) and 95% confidence intervals (CI) were calculated. In both the adjusted and unadjusted models of hypertension, significant associations between the > 1×/week hot spring bathing and the alleviation of hypertension symptoms were observed compared to the group whose hot spring bathing was <1×/week: adjusted model, OR 5.40 (95%CI: 1.98-14.74); unadjusted model, 3.67 (1.50-8.99) and for gastroenteritis: adjusted model, 9.18 (1.15-72.96); unadjusted model, 7.62 (1.59-36.49). Compared to the no-bathing group, higher SRH was significantly associated with both bathing < 1×/week: unadjusted model, 2.27 (1.53-3.37) and > 1×/week: adjusted model, 1.91 (1.15-3.19). These findings suggest that bathing in radon hot springs is associated with higher SRH and the alleviation of hypertension and gastroenteritis. |
| Keywords | radon hot spring bathing habit self-rated health cross-section study |
| Amo Type | Original Article |
| Publication Title | Acta Medica Okayama |
| Published Date | 2023-08 |
| Volume | volume77 |
| Issue | issue4 |
| Publisher | Okayama University Medical School |
| Start Page | 387 |
| End Page | 394 |
| ISSN | 0386-300X |
| NCID | AA00508441 |
| Content Type | Journal Article |
| language | English |
| Copyright Holders | Copyright Ⓒ 2023 by Okayama University Medical School |
| File Version | publisher |
| Refereed | True |
| PubMed ID | 37635139 |
| Web of Science KeyUT | 001163659800003 |
| JaLCDOI | 10.18926/AMO/65741 |
|---|---|
| FullText URL | 77_4_359.pdf |
| Author | Koshida, Tomohiro| Maruta, Toyoaki| Tanaka, Nobuhiko| Hidaka, Kotaro| Kurogi, Mio| Nemoto, Takayuki| Yanagita, Toshihiko| Takeya, Ryu| Tsuneyoshi, Isao| |
| Abstract | Pulsed radiofrequency (PRF) is a safe method of treating neuropathic pain by generating intermittent electric fields at the needle tip. Resiniferatoxin (RTX) is an ultrapotent agonist of transient receptor potential vanilloid subtype-1 (TRPV1) receptors. We investigated the mechanism of PRF using a rat model of RTX-induced neuropathic pain. After administering RTX intraperitoneally, PRF was applied to the right sciatic nerve. We observed the changes in TRPV1, calcitonin gene-related peptide (CGRP), and brain-derived neurotrophic factor (BDNF) in the dorsal root ganglia by western blotting. Expressions of TRPV1 and CGRP were significantly lower in the contralateral (RTX-treated, PRF-untreated) tissue than in control rats (p<0.0001 and p<0.0001, respectively) and the ipsilateral tissues (p<0.0001 and p<0.0001, respectively). BDNF levels were significantly higher in the contralateral tissues than in the control rats (p<0.0001) and the ipsilateral tissues (p<0.0001). These results suggest that, while TRPV1 and CGRP are decreased by RTX-induced neuronal damage, increased BDNF levels result in pain development. PRF may promote recovery from neuronal damage with concomitant restoration of TRPV1 and CGRP, and exert its analgesic effect by reversing BDNF increase. Further research is required to understand the role of TRPV1 and CGRP restoration in improving mechanical allodynia. |
| Keywords | pulsed radiofrequency resiniferatoxin transient receptor potential vanilloid subtype-1 (TRPV1) calcitonin gene-related peptide (CGRP) brain-derived neurotrophic factor (BDNF) |
| Amo Type | Original Article |
| Publication Title | Acta Medica Okayama |
| Published Date | 2023-08 |
| Volume | volume77 |
| Issue | issue4 |
| Publisher | Okayama University Medical School |
| Start Page | 359 |
| End Page | 364 |
| ISSN | 0386-300X |
| NCID | AA00508441 |
| Content Type | Journal Article |
| language | English |
| Copyright Holders | Copyright Ⓒ 2023 by Okayama University Medical School |
| File Version | publisher |
| Refereed | True |
| PubMed ID | 37635135 |
| Web of Science KeyUT | 001163659800011 |
