Development of light-induced disruptive liposomes (LiDL) as a photoswitchable carrier for intracellular substance delivery

Tsuneishi, Taichi; Kojima, Keiichi; Kubota, Fumika; Harashima, Hideyoshi; Yamada, Yuma; Sudo, Yuki

doi:10.1039/d3cc02056h

Permalink : http://escholarship.lib.okayama-u.ac.jp/65508

ID	65508
FullText URL	fulltext20230619-04.pdf 898 KB
Author	Tsuneishi, Taichi Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama University Kojima, Keiichi Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama University ORCID Kaken ID researchmap Kubota, Fumika Faculty of Pharmaceutical Sciences, Hokkaido University Harashima, Hideyoshi Faculty of Pharmaceutical Sciences, Hokkaido University Yamada, Yuma Faculty of Pharmaceutical Sciences, Hokkaido University Sudo, Yuki Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama University ORCID Kaken ID researchmap
Abstract	Light-driven inward proton pump rhodopsin RmXeR was embedded in pH-sensitive liposomes. Substance release from the proteoliposomes was observed following light illumination both in vitro and in cells, indicating the successful production of light-induced disruptive liposomes (LiDL). Thus, LiDL is a photoswitchable carrier utilized for intracellular substance delivery.
Published Date	2023
Publication Title	Chemical Communications
Volume	volume59
Issue	issue49
Publisher	Royal Society of Chemistry (RSC)
Start Page	7591
End Page	7594
ISSN	1359-7345
NCID	AA11071130
Content Type	Journal Article
language	English
OAI-PMH Set	岡山大学
Copyright Holders	© The Royal Society of Chemistry 2023
File Version	publisher
PubMed ID	37254694
DOI	10.1039/d3cc02056h
Web of Science KeyUT	000999015900001
Related Url	isVersionOf https://doi.org/10.1039/D3CC02056H
License	http://creativecommons.org/licenses/by-nc/3.0/