result 2319 件
| JaLCDOI | 10.18926/AMO/49043 |
|---|---|
| FullText URL | 66_6_469.pdf |
| Author | Shiozaki, Yasuyuki| Ito, Yasuo| Sugimoto, Yoshihisa| Tomioka, Masao| Shimokawa, Tetsuya| Mazaki, Tetsuro| Koshimune, Koichiro| Tanaka, Masato| Ozaki, Toshifumi| |
| Abstract | In this study, we studied the relationship between fracture patterns and motor function recovery in 70 consecutive patients with cervical spinal cord injury. Fractures were categorized into 6 fracture types and subdivided into stages according to the Allen-Ferguson classification system:compressive flexion (CF), distractive flexion (DF), compressive extension (CE), distractive extension (DE), vertical compression (VC) and lateral flexion (LF). Paralysis was evaluated using the American Spinal Injury Association (ASIA) impairment scale at the time of injury and 3 months afterwards. The residual rate of complete motor palsy (ASIA grade A or B) at the final examination was higher in those patients with DE fractures than those with CF, DF or CE. The final outcomes were as follows. Of the 14 patients who were classified with CF fractures, residual palsy was frequently seen in patients who had stage 5 injury. Of the 27 patients with DF fractures, residual palsy occurred in about half of the patients who had stage 4 or 5 injury. Of the 18 patients with CE fractures, residual palsy occurred in half of the patients with stage 3 injury or higher. Finally, of the 7 patients with DE fractures, the rate of residual palsy was high even for the stage 1 and 2 cases;indeed, all DE patients who had complete motor palsy at the first examination had residual palsy at the final examination. Accordingly, we conclude that motor recovery may be related to fracture pattern. |
| Keywords | cervical spinal cord injury motor function recovery fracture patterns |
| Amo Type | Original Article |
| Publication Title | Acta Medica Okayama |
| Published Date | 2012-12 |
| Volume | volume66 |
| Issue | issue6 |
| Publisher | Okayama University Medical School |
| Start Page | 469 |
| End Page | 473 |
| ISSN | 0386-300X |
| NCID | AA00508441 |
| Content Type | Journal Article |
| language | English |
| Copyright Holders | CopyrightⒸ 2012 by Okayama University Medical School |
| File Version | publisher |
| Refereed | True |
| PubMed ID | 23254581 |
| Web of Science KeyUT | 000312966100006 |
| Author | Takahashi, Kazuo H.| Daborn, Phillip J.| Hoffmann, Ary A.| Takano-Shimizu, Toshiyuki| |
|---|---|
| Published Date | 2011-04-25 |
| Publication Title | PLoS ONE |
| Volume | volume6 |
| Issue | issue4 |
| Content Type | Journal Article |
| Author | Takahashi, Kazuo H.| Okada, Yasukazu| Teramura, Kouhei| |
|---|---|
| Published Date | 2011-08 |
| Publication Title | Journal of Heredity |
| Volume | volume102 |
| Issue | issue4 |
| Content Type | Journal Article |
| Author | Fukuhara, Kazuma| Phompida, Samlane| Insisiengmay, Sithat| Kirinoki, Masashi| Chigusa, Yuichi| Nakamura, Satoshi| Matsuda, Hajime| Ishikawa, Hirofumi| |
|---|---|
| Published Date | 2011-12 |
| Publication Title | Parasitology International |
| Volume | volume60 |
| Issue | issue4 |
| Content Type | Journal Article |
| Author | Wakita, Takanori| Okazaki, Hiroyuki| Takano, Yoshihiko| Hirai, Masaaki| Muraoka, Yuji| Yokoya, Takayoshi| |
|---|---|
| Published Date | 2010-12 |
| Publication Title | Physica C-Superconductivity and its Applications |
| Volume | volume470 |
| Issue | issueS1 |
| Content Type | Journal Article |
| Author | Yoshida, Rikiya| Nakamura, Yoshiaki| Fukui, Masaki| Haga, Yoshinori| Yamamoto, Etsuji| Onuki, Yoshichika| Okawa, Mario| Shin, Shik| Hirai, Masaaki| Muraoka, Yuji| Yokoya, Takayoshi| |
|---|---|
| Published Date | 2010-11-08 |
| Publication Title | Physical Review B |
| Volume | volume82 |
| Issue | issue20 |
| Content Type | Journal Article |
| Author | Kataoka, Takahiro| Tokunaga, Rikizo| Sakoda, Akihiro| Kawabe, Atsushi| Hanamoto, Katsumi| Yamaoka, Kiyonori| |
|---|---|
| Published Date | 2012-01-27 |
| Publication Title | RADIOISOTOPES |
| Volume | volume61 |
| Issue | issue1 |
| Content Type | Journal Article |
| Author | Kataoka, Takahiro| Mizuguchi, Yuko| Yoshimoto, Masaaki| Taguchi, Takehito| Yamaoka, Kiyonori| |
|---|---|
| Published Date | 2007-11-21 |
| Publication Title | Journal of Radiation Research |
| Volume | volume48 |
| Issue | issue6 |
| Content Type | Journal Article |
| Author | Yamaoka, Kiyonori| Mitsunobu, Fumihiro| Kojima, Shuji| Shibakura, Misako| Kataoka, Takahiro| Hanamoto, Katsumi| Tanizaki, Yoshiro| |
|---|---|
| Published Date | 2005-04-01 |
| Publication Title | Journal of Radiation Research |
| Volume | volume46 |
| Issue | issue1 |
| Content Type | Journal Article |
| JaLCDOI | 10.18926/AMO/48686 |
|---|---|
| FullText URL | 66_4_317.pdf |
| Author | Pak, Wing| Takayama, Fusako| Hasegawa, Azusa| Mankura, Mitsumasa| Egashira, Toru| Ueki, Keiji| Nakamoto, Kazuo| Kawasaki, Hiromu| Mori, Akitane| |
| Abstract | This study aimed to investigate the therapeutic effects of the water extract of leaves of Vitis coignetiae Pulliat (VCPL) on nonalcoholic steatohepatitis (NASH) with advanced fibrosis, as our previous study exhibited its preventive effect on NASH. The NASH animal model [PCT/JP2007/52477] was prepared by loading recurrent and intermittent hypoxemia stress to a rat with fatty liver, which resembled the condition occurring in patients with obstructive sleep apnea (OSA) and fatty liver, who have a high incidence of NASH. Intermittent hypoxemia stress is regarded as a condition similar to warm ischemia followed by re-oxygenation, which induces oxidative stress (OS). The daily 100 or 300mg/kg VCPL administrations were performed for 3 weeks perorally beginning at the time of detection of advanced liver fibrosis. The therapeutic efficacy of VCPL on NASH was demonstrated by the reduction of the leakage of hepato-biliary enzymes and the amelioration of liver fibrosis. The OS elevation in NASH rats was measured based on the derivation of reactive oxygen species from liver mitochondrial energy metabolism and on the decrease in plasma SOD-like activity. The aggravation of inflammatory responses was demonstrated by the neutrophil infiltration (elevated myeloperoxidase activity) and the progression of fibrosis in the livers of NASH rats. In addition, the NASH rats without VCPL treatment also exhibited activation of nuclear factor-κB, a key factor in the link between oxidative stress and inflammation. All of these changes were reduced dose-dependently by the VCPL administration. These findings indicate that VCPL may improve hepatic fibrosis or at least suppress the progression of NASH, by breaking the crosstalk between OS and inflammation. |
| Keywords | non-alcoholic steatohepatitis antioxidative oxidative stress anti-inflammation Vitis coignetiae Pulliat |
| Amo Type | Original Article |
| Publication Title | Acta Medica Okayama |
| Published Date | 2012-08 |
| Volume | volume66 |
| Issue | issue4 |
| Publisher | Okayama University Medical School |
| Start Page | 317 |
| End Page | 327 |
| ISSN | 0386-300X |
| NCID | AA00508441 |
| Content Type | Journal Article |
| language | English |
| Copyright Holders | CopyrightⒸ 2012 by Okayama University Medical School |
| File Version | publisher |
| Refereed | True |
| PubMed ID | 22918204 |
| Web of Science KeyUT | 000307918900004 |
| Author | Hisatomi, Miki| Yanagi, Yoshinobu| Konouchi, Hironobu| Matsuzaki, Hidenobu| Takenobu, Toshihiko| Unetsubo, Teruhisa| Asaumi, Jun-ichi| |
|---|---|
| Published Date | 2011-02 |
| Publication Title | Oral Oncology |
| Volume | volume47 |
| Issue | issue2 |
| Content Type | Journal Article |
| Author | Ma, Shaobo| |
|---|---|
| Published Date | 2012-08-01 |
| Publication Title | 岡山医学会雑誌 |
| Volume | volume124 |
| Issue | issue2 |
| Content Type | Journal Article |
| Author | Nagai, Yusuke| |
|---|---|
| Published Date | 2012-02 |
| Publication Title | Biomaterials |
| Volume | volume33 |
| Issue | issue4 |
| Content Type | Journal Article |
| JaLCDOI | 10.18926/AMO/48568 |
|---|---|
| FullText URL | 66_3_279.pdf |
| Author | Nishimura, Mamoru| Nouso, Kazuhiro| Kariyama, Kazuya| Wakuta, Akiko| Kishida, Masayuki| Wada, Nozomu| Higashi, Toshihiro| Yamamoto, Kazuhide| |
| Abstract | The artificial ascites technique is often used during radiofrequency ablation (RFA) for hepatocellular carcinoma (HCC) treatment because it prevents visceral damage and improves visualization by minimizing interference of the lungs and mesentery. This study determined the efficacy and safety of RFA using the artificial ascites technique in HCC patients. We examined 188 HCC patients who were treated by RFA and fulfilled the Milan criteria. Treatment outcomes (complete ablation rate, local recurrence rate, complication rate, liver function including total bilirubin level, alanine aminotransferase level, albumin level, and prothrombin time) were compared among patients divided into 3 groups based on the volume of artificial ascites injected:GroupⅠ (n＝86), no artificial ascites injected;GroupⅡ (n＝35), ＜1,000ml artificial ascites injected;and Group Ⅲ (n＝67), ＞1,000ml artificial ascites injected. No significant difference was observed in complete ablation or local recurrence rates among the 3 groups, or in the extent of liver function damage after RFA. Artificial ascites disappeared within 7 days; additional diuretics were needed only in 5 (all from Group Ⅲ) of 102 patients. No serious complications such as intestinal perforation or intraperitoneal bleeding were observed. Thus, we found that artificial ascites injection during RFA is effective and safe, and can be used to prevent major procedural complications. |
| Keywords | radiofrequency ablation hepatocellular carcinoma artificial ascites |
| Amo Type | Original Article |
| Publication Title | Acta Medica Okayama |
| Published Date | 2012-06 |
| Volume | volume66 |
| Issue | issue3 |
| Publisher | Okayama University Medical School |
| Start Page | 279 |
| End Page | 284 |
| ISSN | 0386-300X |
| NCID | AA00508441 |
| Content Type | Journal Article |
| language | English |
| Copyright Holders | CopyrightⒸ 2012 by Okayama University Medical School |
| File Version | publisher |
| Refereed | True |
| PubMed ID | 22729109 |
| Web of Science KeyUT | 000305669700012 |
| JaLCDOI | 10.18926/AMO/48562 |
|---|---|
| FullText URL | 66_3_231.pdf |
| Author | Takahashi, Kingo| Hayashi, Masamichi| Fujii, Toshihiro| Kawamura, Kenji| Ozaki, Toshifumi| |
| Abstract | The objective of early rehabilitation after anterior cruciate ligament (ACL) reconstruction is to increase the muscle strength of the lower extremities. Closed kinetic chain (CKC) exercise induces co-contraction of the agonist and antagonist muscles. The purpose of this study was to compare the postoperative muscle strength/mass of subjects who performed our new CKC exercise (new rehabilitation group:group N) from week 4, and subjects who received traditional rehabilitation alone (traditional rehabilitation group:group T). The subjects stood on the device and maintained balance. Then, low-frequency stimulation waves were applied to 2 points each in the anterior and posterior region of the injured thigh 3 times a week for 3 months. Measurement of muscle strength was performed 4 times (before the start, and then once a month). Muscle mass was evaluated in CT images of the extensor and flexor muscles of 10 knees (10 subjects) in each group. The injured legs of group N showed significant improvement after one month compared to group T. The cross-sectional area of the extensor muscles of the injured legs tended to a show a greater increase at 3 months in group N. This rehabilitation method makes it possible to contract fast-twitch muscles, which may be a useful for improving extensor muscle strength after ACL reconstruction. |
| Keywords | anterior cruciate ligament reconstruction closed kinetic chain electrical muscle stimulation standing-shaking-board exercise |
| Amo Type | Original Article |
| Publication Title | Acta Medica Okayama |
| Published Date | 2012-06 |
| Volume | volume66 |
| Issue | issue3 |
| Publisher | Okayama University Medical School |
| Start Page | 231 |
| End Page | 237 |
| ISSN | 0386-300X |
| NCID | AA00508441 |
| Content Type | Journal Article |
| language | English |
| Copyright Holders | CopyrightⒸ 2012 by Okayama University Medical School |
| File Version | publisher |
| Refereed | True |
| PubMed ID | 22729103 |
| Web of Science KeyUT | 000305669700006 |
| Author | Seki, Masako| |
|---|---|
| Published Date | 2012-03-23 |
| Publication Title | |
| Content Type | Thesis or Dissertation |
| JaLCDOI | 10.18926/AMO/48080 |
|---|---|
| FullText URL | 66_1_41.pdf |
| Author | Ohtsu, Tadahiro| Kaneita, Yoshitaka| Ishimura, Yohei| Aritake, Sayaka| Mishima, Kazuo| Uchiyama, Makoto| Akashiba, Tsuneto| Uchimura, Naohisa| Nakaji, Shigeyuki| Munezawa, Takeshi| Shimada, Naoki| Kokaze, Akatsuki| Ohida, Takashi| |
| Abstract | Little research has been done on the association between relaxation and health. In the present study, by conducting a nationwide cross-sectional survey, we aimed to obtain scientific data on the preferable forms of relaxation for health promotion, and to clarify the associations between specific recreational activities and self-perceived mental and physical health. We selected 4,000 households by stratified random sampling from across Japan in November 2009 and used the interview method to collect data (number of subjects:2,206). The questionnaire contained items on sleep, recreation status, recreational activities, and self-perceived mental and physical health status. We obtained responses from 1,224 adults (response rate:55.5%). Insufficient rest from sleep, short sleep duration (＜6h/day), ineffective use of free time, and less free time used for activities other than rest showed independent positive associations with poor mental and physical health. The results of the logistic regression analyses showed significantly low adjusted odds ratios with regard to the status of poor mental and physical health for outings/walking among men (0.33 [95% confidence interval;0.16-0.68] and 0.49 [0.26-0.90], respectively), and for community activities among women (0.19 [0.04-0.79] and 0.27 [0.09-0.77], respectively). Relaxation for the promotion of health should include both passive relaxation (rest) and active relaxation (recreation). In addition, ensuring sufficient sleep duration is important for passive relaxation, and engaging in outings/walking for men and community activities for women are important for active relaxation. |
| Keywords | passive relaxation active relaxation recreational activity self-perceived health |
| Amo Type | Original Article |
| Publication Title | Acta Medica Okayama |
| Published Date | 2012-02 |
| Volume | volume66 |
| Issue | issue1 |
| Publisher | Okayama University Medical School |
| Start Page | 41 |
| End Page | 51 |
| ISSN | 0386-300X |
| NCID | AA00508441 |
| Content Type | Journal Article |
| language | English |
| Copyright Holders | CopyrightⒸ 2012 by Okayama University Medical School |
| File Version | publisher |
| Refereed | True |
| PubMed ID | 22358138 |
| Web of Science KeyUT | 000300800700006 |
| Author | Tsuda, Makoto| Ueda, Yukie| Hirai, Yoshihiko| |
|---|---|
| Published Date | 2012-02-01 |
| Publication Title | 岡山大学農学部学術報告 |
| Volume | volume101 |
| Content Type | Departmental Bulletin Paper |
| Author | Singaravel, Muniyandi| Fujisawa, Yuko| Hisada, Miki| Saifullah, ASM| Tomioka, Kenji| |
|---|---|
| Published Date | 2003-11 |
| Publication Title | Zoological Science |
| Volume | volume20 |
| Issue | issue11 |
| Content Type | Journal Article |
| Author | Tomioka, Kenji| Abdelsalam, Salaheldin| |
|---|---|
| Published Date | 2004-12 |
| Publication Title | Zoological Science |
| Volume | volume21 |
| Issue | issue12 |
| Content Type | Journal Article |
