result 23573 件
| Author | Ōshima, Hideaki| Ōshima, Katsumi| |
|---|---|
| Published Date | 2015-01 |
| Publication Title | Mathematical Journal of Okayama University |
| Volume | volume57 |
| Issue | issue1 |
| Content Type | Journal Article |
| JaLCDOI | 10.18926/mjou/53039 |
| Title Alternative | Die Intellekutelle und die `Bildung' : Der Bildungsgedanke von Maruyama Masao |
|---|---|
| FullText URL | olj_064_2_269_317.pdf |
| Author | Nishimura, M.| |
| Publication Title | 岡山大學法學會雜誌 |
| Published Date | 2014-12-26 |
| Volume | volume64 |
| Issue | issue2 |
| Start Page | 269 |
| End Page | 317 |
| ISSN | 0386-3050 |
| language | Japanese |
| File Version | publisher |
| NAID | 120005525337 |
| Title Alternative | A Study on Surrender of Security by Creditor : Historical and Comparative Perspectives (10) |
|---|---|
| FullText URL | olj_064_2_253_268.pdf |
| Author | Tsuji, H.| |
| Publication Title | 岡山大學法學會雜誌 |
| Published Date | 2014-12-26 |
| Volume | volume64 |
| Issue | issue2 |
| Start Page | 253 |
| End Page | 268 |
| ISSN | 0386-3050 |
| language | Japanese |
| File Version | publisher |
| NAID | 120005525336 |
| Title Alternative | The Substantive Law Approach to the Statute of Limitations |
|---|---|
| FullText URL | olj_064_2_348_330.pdf |
| Author | Harada, K.| |
| Publication Title | 岡山大學法學會雜誌 |
| Published Date | 2014-12-26 |
| Volume | volume64 |
| Issue | issue2 |
| Start Page | 348 |
| End Page | 330 |
| ISSN | 0386-3050 |
| language | Japanese |
| File Version | publisher |
| NAID | 120005525335 |
| FullText URL | olj_064_2_388_349.pdf |
|---|---|
| Author | Takeuchi, M.| |
| Publication Title | 岡山大學法學會雜誌 |
| Published Date | 2014-12-26 |
| Volume | volume64 |
| Issue | issue2 |
| Start Page | 388 |
| End Page | 349 |
| ISSN | 0386-3050 |
| language | English |
| File Version | publisher |
| NAID | 120005525334 |
| JaLCDOI | 10.18926/AMO/53025 |
|---|---|
| FullText URL | 68_6_363.pdf |
| Author | Ota, Seisuke| Hiramatsu, Yasushi| Kondo, Eisei| Kasahara, Akinori| Takada, Saimon| Umena, Sachio| Noguchi, Toshio| Tanimoto, Mitsune| Matsumura, Tadashi| |
| Abstract | Leukocytosis is occasionally seen in patients with presumptive but undiagnosed myeloproliferative disorders (MPD). A 74-year-old woman was admitted to our hospital for tarry stools, anemia, and marked peripheral leukocytosis of 1.4×105/μL. Gastroenteroscopy revealed an acute gastric and duodenal mucosal lesion that was treated successfully via endoscopic hemoclipping. Bone marrow aspiration revealed marked megakaryocyte proliferation with atypia of naked nuclei and marrow hypercellularity (90% cellularity). A fluorescence in situ hybridization test could not detect the BCR-ABL fusion gene. Bone marrow aspiration later revealed further abnormalities of megakaryocytes. The patient died from cerebral bleeding. The present case fulfilled 2 of the 3 major criteria of primary myelofibrosis according to the World Health Organization 2008 classification:namely, megakaryocytic hyperplasia with hypercellular marrow and granulocytic hyperplasia. However, the megakaryocytic abnormality was not strictly compatible with the criteria. Instead, we considered prefibrotic primary myelofibrosis as a possibility, although myelodysplastic syndrome/myeloproliferative neoplasm, unclassifiable (MDS/MPN-U) was technically the correct diagnosis. The present case shows that MPN diagnosis remains difficult and suggests that other cases of peripheral leukocytosis with diagnosed MDS/MPN-U might include similar findings. |
| Keywords | prefibrotic primary myelofibrosis leukocytosis anemia acute gastric mucosal lesion multiple cerebral hemorrhages |
| Amo Type | Case Report |
| Publication Title | Acta Medica Okayama |
| Published Date | 2014-12 |
| Volume | volume68 |
| Issue | issue6 |
| Publisher | Okayama University Medical School |
| Start Page | 363 |
| End Page | 368 |
| ISSN | 0386-300X |
| NCID | AA00508441 |
| Content Type | Journal Article |
| language | English |
| Copyright Holders | CopyrightⒸ 2014 by Okayama University Medical School |
| File Version | publisher |
| Refereed | True |
| PubMed ID | 25519030 |
| Web of Science KeyUT | 000346882200006 |
| JaLCDOI | 10.18926/AMO/53024 |
|---|---|
| FullText URL | 68_6_349.pdf |
| Author | Yamamoto, Tsuyoshi| Kajikawa, Yutaka| Otani, Satoru| Yamada, Yuki| Takemoto, Syunji| Hirota, Minoru| Ikeda, Masae| Iwagaki, Hiromi| Saito, Shinya| Fujiwara, Toshiyoshi| |
| Abstract | Accumulated studies have shown that ω-3 polyunsaturated fatty acids such as eicosapentaenoic acid (EPA) have protective roles against inflammatory responses such as hyperlipidemia, diabetes mellitus (DM) and cardiovascular diseases. Here we examined the effects of administering EPA to hyperlipidemic patients and other patients undergoing cardiac surgery to determine whether this treatment would increase plasma EPA levels and to clarify the association between EPA treatment and adiponectin production in hyperlipidemic patients. We also assessed the effect of preoperative EPA administration on postoperative adverse events such as postoperative atrial fibrillation (POAF) and postoperative infection in the cardiac surgery patients. The EPA administration significantly increased the serum EPA concentrations in both patient populations (p＜0.001). In the hyperlipidemic patients, the EPA administration significantly increased plasma adiponectin levels (p＜0.05), accompanied by a decrease in insulin resistance designated by the HOMA-IR (homeostasis model assessment of insulin resistance) score (p＜0.05) and Hs-CRP (high sensitivity C-reactive protein) value (p＜0.05). In the cardiac surgery patients, no significant effect of EPA on cardiac adverse events such as POAF was observed. However, our results clearly demonstrated that both the neutrophil-to-lymphocyte ratio and the 2nd-line antibiotic requirement in the EPA group were significantly decreased compared to the untreated control group (p＜0.05). We suggest that EPA administration may exert anti-inflammatory effects in patients with hyperlipidemia and in those undergoing cardiac surgery, possibly through an increase in plasma adiponectin levels. |
| Keywords | eicosapentaenoic acid adiponectin hyperlipidemic patients cardiac surgery atrial fibrillation |
| Amo Type | Original Article |
| Publication Title | Acta Medica Okayama |
| Published Date | 2014-12 |
| Volume | volume68 |
| Issue | issue6 |
| Publisher | Okayama University Medical School |
| Start Page | 349 |
| End Page | 361 |
| ISSN | 0386-300X |
| NCID | AA00508441 |
| Content Type | Journal Article |
| language | English |
| Copyright Holders | CopyrightⒸ 2014 by Okayama University Medical School |
| File Version | publisher |
| Refereed | True |
| PubMed ID | 25519029 |
| Web of Science KeyUT | 000346882200005 |
| Related Url | http://ousar.lib.okayama-u.ac.jp/metadata/53125 |
| JaLCDOI | 10.18926/AMO/53023 |
|---|---|
| FullText URL | 68_6_339.pdf |
| Author | Nishie, Hiroyuki| Mizobuchi, Satoshi| Suzuki, Etsuji| Sato, Kenji| Toda, Yuichiro| Matsuoka, Junji| Morimatsu, Hiroshi| |
| Abstract | The main purpose of this study was to determine the relationships between Japanese individualsʼ interest in living wills and their preferred end-of-life care and death locations. Questionnaires were mailed to 1,000 individuals aged ｧ50 to measure these 2 factors. We examined the associations between the respondentsʼ characteristics and their preferred care and death locations by using multinomial logistic regression models. The response rate was 74%. Home was the most frequently preferred place for end-of-life care (64%), and a palliative care unit (PCU) was the most commonly preferred place to die (51%). Living will interest was associated with a preference for care (odds ratio [OR] 4.74, 95% confidence interval [CI] 1.95-12.1) and death (OR 2.75, 95% CI 1.70-4.47) in a PCU rather than a hospital, but it was not associated with the choice between receiving care or dying at home instead of a hospital. We must consider why Japanese people think home death is impracticable. The Japanese palliative care system should be expanded to meet patientsʼ end-of-life needs, and this includes not only facilitating home care but also increasing access to PCU care. |
| Keywords | advance healthcare directive living will end-of-life care palliative care unit place of death |
| Amo Type | Original Article |
| Publication Title | Acta Medica Okayama |
| Published Date | 2014-12 |
| Volume | volume68 |
| Issue | issue6 |
| Publisher | Okayama University Medical School |
| Start Page | 339 |
| End Page | 348 |
| ISSN | 0386-300X |
| NCID | AA00508441 |
| Content Type | Journal Article |
| language | English |
| Copyright Holders | CopyrightⒸ 2014 by Okayama University Medical School |
| File Version | publisher |
| Refereed | True |
| PubMed ID | 25519028 |
| Web of Science KeyUT | 000346882200004 |
| Related Url | http://ousar.lib.okayama-u.ac.jp/metadata/53134 |
| JaLCDOI | 10.18926/AMO/53022 |
|---|---|
| FullText URL | 68_6_331.pdf |
| Author | Ohtsu, Tadahiro| Kaneita, Yoshitaka| Osaki, Yoneatsu| Kokaze, Akatsuki| Ochiai, Hirotaka| Shirasawa, Takako| Nanri, Hinako| Ohida, Takashi| |
| Abstract | The purposes of this study were to evaluate the mental health status of Japanese medical students and to examine differences based on gender, as well as on university type and location, using the results of a nationwide survey. Between December 2006 and March 2007, we conducted a questionnaire survey among fourth-year medical students at 20 randomly selected medical schools in Japan. The data from 1,619 students (response rate:90.6%;male:1,074;female:545) were analyzed. We used the Japanese version of the 12-item General Health Questionnaire (GHQ-12) to measure mental health status. Poor mental health status (GHQ-12 score of 4 points or higher) was observed in 36.6% and 48.8% of the male and female medical students, respectively. The ratio of the age-adjusted prevalence of poor mental health status in female versus male medical students was 1.33 (95% confidence interval:1.10-1.62). The universities were categorized into two groups based on the university type (national/public:15 vs. private:5) or location (in a large city:7 vs. in a local city:13 cities). The prevalence of poor mental health status in both men and women differed between these groups, although not significantly. The GHQ-12 scores in men significantly differed between the categorized groups of universities. These results suggest that adequate attention must be paid to the mental health of medical students, especially females, and that a system for providing mental health care for medical students must be established in the context of actual conditions at each university. |
| Keywords | medical students mental health 12-item General Health Questionnaire gender difference Japan |
| Amo Type | Original Article |
| Publication Title | Acta Medica Okayama |
| Published Date | 2014-12 |
| Volume | volume68 |
| Issue | issue6 |
| Publisher | Okayama University Medical School |
| Start Page | 331 |
| End Page | 337 |
| ISSN | 0386-300X |
| NCID | AA00508441 |
| Content Type | Journal Article |
| language | English |
| Copyright Holders | CopyrightⒸ 2014 by Okayama University Medical School |
| File Version | publisher |
| Refereed | True |
| PubMed ID | 25519027 |
| Web of Science KeyUT | 000346882200003 |
| JaLCDOI | 10.18926/AMO/53020 |
|---|---|
| FullText URL | 68_6_317.pdf |
| Author | Kasahara, Kyosuke| Miyoshi, Ko| Murakami, Shinki| Miyazaki, Ikuko| Asanuma, Masato| |
| Abstract | In vertebrates, almost all somatic cells extend a single immotile cilium, referred to as a primary cilium. Increasing evidence suggests that primary cilia serve as cellular antennae in many types of tissues by sensing chemical or mechanical stimuli in the milieu surrounding the cells. In rodents an antibody to adenylyl cyclase 3 (AC3) has been widely used to label the primary cilia of neurons in vivo by immunostaining, whereas the lack of markers for the primary cilia of astrocytes has made it difficult to observe astrocytic primary cilia in vivo. Here, we obtained a visualization of astrocytic primary cilia in the mouse brain. In the somatosensory cortex, a large portion of neurons and astrocytes at postnatal day 10 (P10), and of neurons at P56 had AC3-positive primary cilia, whereas only approx. one-half of the astrocytes in the P56 mice carried primary cilia weakly positive for AC3. In contrast, the majority of astrocytes had ADP-ribosylation factor-like protein 13B (Arl13b)-positive primary cilia in the somatosensory cortex and other brain regions of P56 mice. The lengths of astrocytic primary cilia positive for Arl13b varied among the brain regions. Our data indicate that Arl13b is a noteworthy marker of astrocytic primary cilia in the brain. |
| Keywords | primary cilia astrocyte ADP-ribosylation factor-like protein 13B |
| Amo Type | Original Article |
| Publication Title | Acta Medica Okayama |
| Published Date | 2014-12 |
| Volume | volume68 |
| Issue | issue6 |
| Publisher | Okayama University Medical School |
| Start Page | 317 |
| End Page | 322 |
| ISSN | 0386-300X |
| NCID | AA00508441 |
| Content Type | Journal Article |
| language | English |
| Copyright Holders | CopyrightⒸ 2014 by Okayama University Medical School |
| File Version | publisher |
| Refereed | True |
| PubMed ID | 25519025 |
| Web of Science KeyUT | 000346882200001 |
| Author | Abe, N| Hou, D-X| Munemasa, S| Murata, Y| Nakamura, Y| |
|---|---|
| Published Date | 2014-11-20 |
| Publication Title | Cell Death and Disease |
| Volume | volume5 |
| Content Type | Journal Article |
| FullText URL | Bri_Jou_Der_171_3_492-498.pdf |
|---|---|
| Author | Takiguchi, T| Morizane, S| Yamamoto, T| Kajita, A| Ikeda, K| Iwatsuki, K| |
| Note | This is the accepted version of the following article: FULLCITE, which has been published in final form at http://dx.doi.org/10.1111/bjd.12942| 学位審査副論文| |
| Published Date | 2014-09 |
| Publication Title | British Journal of Dermatology |
| Volume | volume171 |
| Issue | issue3 |
| Start Page | 492 |
| End Page | 498 |
| ISSN | 0007-0963 |
| Content Type | Journal Article |
| language | English |
| OAI-PMH Set | 岡山大学 |
| Copyright Holders | © 2014 British Association of Dermatologists |
| File Version | author |
| PubMed ID | 24601852 |
| DOI | 10.1111/bjd.12942 |
| Web of Science KeyUT | 000344006900186 |
| Related Url | http://ousar.lib.okayama-u.ac.jp/metadata/52974 http://ousar.lib.okayama-u.ac.jp/53764 |
| Author | Kobayashi, Tomoko| Suzuki, Etsuji| Oksanen, Tuula| Kawachi, Ichiro| Takao, Soshi| |
|---|---|
| Published Date | 2014-01-31 |
| Publication Title | PLoS ONE |
| Volume | volume9 |
| Issue | issue1 |
| Content Type | Journal Article |
| Author | Mizoo, Taeko| Taira, Naruto| Nishiyama, Keiko| Nogami, Tomohiro| Iwamoto, Takayuki| Motoki, Takayuki| Shien, Tadahiko| Matsuoka, Junji| Doihara, Hiroyoshi| Ishihara, Setsuko| Kawai, Hiroshi| Kawasaki, Kensuke| Ishibe, Youichi| Ogasawara, Yutaka| Komoike, Yoshifumi| Miyoshi, Shinichiro| |
|---|---|
| Published Date | 2013-12-01 |
| Publication Title | BMC Cancer |
| Volume | volume13 |
| Content Type | Journal Article |
| Author | Uchida, Daisuke| Shiraha, Hidenori| Kato, Hironari| Nagahara, Teruya| Iwamuro, Masaya| Kataoka, Junro| Horiguchi, Shigeru| Watanabe, Masami| Takaki, Akinobu| Nouso, Kazuhiro| Nasu, Yasutomo| Yagi, Takahito| Kumon, Hiromi| Yamamoto, Kazuhide| |
|---|---|
| Published Date | 2014-05 |
| Publication Title | Journal of Gastroenterology and Hepatology |
| Volume | volume29 |
| Issue | issue5 |
| Content Type | Journal Article |
| Author | Ishida, Joji| Onishi, Manabu| Kurozumi, Kazuhiko| Ichikawa, Tomotsugu| Fujii, Kentaro| Shimazu, Yosuke| Oka, Tetsuo| Date, Isao| |
|---|---|
| Published Date | 2014-04 |
| Publication Title | Translational Oncology |
| Volume | volume7 |
| Issue | issue2 |
| Content Type | Journal Article |
| Author | Tokioka, Koji| Kusano, Kengo F.| Morita, Hiroshi| Miura, Daiji| Nishii, Nobuhiro| Nagase, Satoshi| Nakamura, Kazufumi| Kohno, Kunihisa| Ito, Hiroshi| Ohe, Tohru| |
|---|---|
| Published Date | 2014-05-27 |
| Publication Title | Journal of the American College of Cardiology |
| Volume | volume63 |
| Issue | issue20 |
| Content Type | Journal Article |
| Author | Alamusi| Matsuo, Toshihiko| Hosoya, Osamu| Tsutsui, Kimiko M.| Uchida, Tetsuya| |
|---|---|
| Published Date | 2013-09 |
| Publication Title | Journal of Artificial Organs |
| Volume | volume16 |
| Issue | issue3 |
| Content Type | Journal Article |
| Author | Mazaki, Tetsuro| Shiozaki, Yasuyuki| Yamane, Kentaro| Yoshida, Aki| Nakamura, Mariko| Yoshida, Yasuhiro| Zhou, Di| Kitajima, Takashi| Tanaka, Masato| Ito, Yoshihiro| Ozaki, Toshifumi| Matsukawa, Akihiro| |
|---|---|
| Published Date | 2014-03-25 |
| Publication Title | Scientific Reports |
| Volume | volume4 |
| Content Type | Journal Article |
| Author | Tsuji, Kenji| Kitamura, Shinji| Makino, Hirofumi| |
|---|---|
| Published Date | 2014-04-25 |
| Publication Title | Biochemical and Biophysical Research Communications |
| Volume | volume447 |
| Issue | issue1 |
| Content Type | Journal Article |
