result 19480 件
| JaLCDOI | 10.18926/AMO/45268 |
|---|---|
| FullText URL | 65_2_97.pdf |
| Author | Tsuchihashi, Yuuki| Yorifuji, Takashi| Takao, Soshi| Suzuki, Etsuji| Mori, Shigeru| Doi, Hiroyuki| Tsuda, Toshihide| |
| Abstract | Seasonal influenza infection is a major challenge in public health. The term "seasonal influenza" refers to the typical increase in the number of influenza patients in the winter season in temperature zones. However, it is not clear how environmental factors within a single flu season affect influenza infection in a human population. Therefore, we evaluated the effects of temperature and humidity in the 2006-7 flu season on the onset of seasonal influenza using a case-crossover study. We targeted patients who attended one pediatric clinic in Okayama city, Japan and who were diagnosed as being infected with the seasonal influenza virus. Using 2 references (time-stratified and symmetric bidirectional design), we estimated the effects of average temperature and relative humidity from the onset day (lag0) to 10 days before (lag10). The total number of subjects was 419, and their onset days ranged from 26 December 2006 to 30 April 2007. While the onset was significantly associated with lower temperature, relative humidity was not related. In particular, temperatures before the 3-day incubation period had higher-magnitude odds ratios. For example, the odds ratio and 95% confidence interval for average temperature at time lag 8 was 1.12 (1.08-1.17) per 1.0℃ decrease. Low environmental temperature significantly increased the risk of seasonal influenza onset within the 2006-7 winter season. |
| Keywords | seasonal influenza in humans temperature humidity case-crossover study |
| Amo Type | Original Article |
| Publication Title | Acta Medica Okayama |
| Published Date | 2011-04 |
| Volume | volume65 |
| Issue | issue2 |
| Publisher | Okayama University Medical School |
| Start Page | 97 |
| End Page | 103 |
| ISSN | 0386-300X |
| NCID | AA00508441 |
| Content Type | Journal Article |
| language | English |
| Copyright Holders | CopyrightⒸ 2011 by Okayama University Medical School |
| File Version | publisher |
| Refereed | True |
| PubMed ID | 21519367 |
| Web of Science KeyUT | 000289818800005 |
| JaLCDOI | 10.18926/AMO/45267 |
|---|---|
| FullText URL | 65_2_91.pdf |
| Author | Nagamatsu, Tomohiro| Sakoda, Akihiro| Kataoka, Takahiro| Ono, Toshiro| Yamaoka, Kiyonori| |
| Abstract | No research has been conducted on the radiation influence of tobacco on the alimentary system, although there have been some previous works on the respiratory system. In this study, the radioactive concentrations of 210Pb and 40K in a cigarette sample were first measured. The transfer factors of the nuclides from tobacco into smoke and solution (saliva and/or alcohol) were then examined. Moreover, the radiation doses from smoke inhalation were also evaluated. The radioactive concentrations of 210Pb and 40K in the cigarette tobacco were 0.01 and 0.3 Bq/cigarette. Since this 210Pb activity and the 210Po activity previously reported for the same sample were comparable, it can be concluded that there was a radioactive equilibrium between the 2 nuclides. The observed transfer factor of 210Pb (12%) into smoke was almost the same as that of 40K (15%), whereas the reported value for 210Po (60%) was significantly higher. The radiation doses due to inhalation of cigarette smoke varied from organ to organ, depending on the organotropic properties of the nuclide. For example, the kidneys, respiratory tract, and spleen showed relatively high doses from 210Pb and 210Po. The leaching rates indicated an inconsistent tendency related to solution types. This result could suggest that alcohol drinking, which is common in smokers, does not especially enhance the leaching characteristics. |
| Keywords | tobacco radionuclides smoking intake radiation exposure |
| Amo Type | Original Article |
| Publication Title | Acta Medica Okayama |
| Published Date | 2011-04 |
| Volume | volume65 |
| Issue | issue2 |
| Publisher | Okayama University Medical School |
| Start Page | 91 |
| End Page | 95 |
| ISSN | 0386-300X |
| NCID | AA00508441 |
| Content Type | Journal Article |
| language | English |
| Copyright Holders | CopyrightⒸ 2011 by Okayama University Medical School |
| File Version | publisher |
| Refereed | True |
| PubMed ID | 21519366 |
| Web of Science KeyUT | 000289818800004 |
| JaLCDOI | 10.18926/AMO/45266 |
|---|---|
| FullText URL | 65_2_81.pdf |
| Author | Sasaki, Motofumi| Shikata, Kenichi| Okada, Shinichi| Miyamoto, Satoshi| Nishishita, Shingo| Usui Kataoka, Hitomi| Sato, Chikage| Wada, Jun| Ogawa, Daisuke| Makino, Hirofumi| |
| Abstract | Glomerular hyperfiltration is a common pathway leading to glomerulosclerosis in various kinds of kidney diseases. The 5/6 renal ablation is an established experimental animal model for glomerular hyperfiltration. On the other hand, low-grade inflammation is also a common mechanism for the progression of kidney diseases including diabetic nephropathy and atherosclerosis. Here we analyzed the gene expression profile in the remnant kidney tissues of 5/6 nephrectomized mice using a DNA microarray system and compared it with that of sham-operated control mice. The 5/6 nephrectomized mice showed glomerular hypertrophy and an increase in the extracellular matrix in the glomeruli. DNA microarray analysis indicated the up-regulated expression of various kinds of genes related to the inflammatory process in remnant kidneys. We confirmed the up-regulated expression of platelet factor-4, and monocyte chemoattractant protein-1, 2, and 5 in remnant kidneys by RT-PCR. The current results suggest that the inflammatory process is involved in the progression of glomerulosclerosis and is a common pathway of the pathogenesis of kidney disease. |
| Keywords | kidney inflammation chemokine |
| Amo Type | Original Article |
| Publication Title | Acta Medica Okayama |
| Published Date | 2011-04 |
| Volume | volume65 |
| Issue | issue2 |
| Publisher | Okayama University Medical School |
| Start Page | 81 |
| End Page | 89 |
| ISSN | 0386-300X |
| NCID | AA00508441 |
| Content Type | Journal Article |
| language | English |
| Copyright Holders | CopyrightⒸ 2011 by Okayama University Medical School |
| File Version | publisher |
| Refereed | True |
| PubMed ID | 21519365 |
| Web of Science KeyUT | 000289818800003 |
| JaLCDOI | 10.18926/AMO/45265 |
|---|---|
| FullText URL | 65_2_71.pdf |
| Author | Sato, Kimiko| Oda, Megumi| |
| Abstract | A questionnaire survey was administered to 317 parents who attended infant health check-ups in City B, Okayama Prefecture between October, 2008 and March, 2009. The questionnaire survey studied 7 factors based on the PRECEDE-PROCEED Model. We analysed factors that affected oral health behaviour and attendance at scheduled dental health check-ups. The survey containing 22 items concerning matters such as 'QOL' and 'health problems' was posted to parents and guardians in advance, and then collected on the day of the medical check-up. The collected data was analysed using the t-test and Pearson's correlation coefficient, following which we conducted a covariance structure analysis. The results showed that dental health behaviour was directly affected by reinforcing factors, and indirectly associated with enabling and predisposing factors influenced by reinforcing factors. It was also shown that predisposing factors and oral health behaviour were associated with attendance at scheduled oral health check-ups. The results indicated that strengthening oral health education by sharing knowledge that acts as predisposing factors and introducing adaptations of oral health behaviour that that fit individual lives will lead to improved attendance at scheduled dental health check-ups. |
| Keywords | PRECEDE-PROCEED model dental check-ups dental health behaviour |
| Amo Type | Original Article |
| Publication Title | Acta Medica Okayama |
| Published Date | 2011-04 |
| Volume | volume65 |
| Issue | issue2 |
| Publisher | Okayama University Medical School |
| Start Page | 71 |
| End Page | 80 |
| ISSN | 0386-300X |
| NCID | AA00508441 |
| Content Type | Journal Article |
| language | English |
| Copyright Holders | CopyrightⒸ 2011 by Okayama University Medical School |
| File Version | publisher |
| Refereed | True |
| PubMed ID | 21519364 |
| Web of Science KeyUT | 000289818800002 |
| JaLCDOI | 10.18926/AMO/45264 |
|---|---|
| FullText URL | 65_2_63.pdf |
| Author | Mizoguchi, Yoshinori| Suzuki, Etsuji| Tsuchida, Hiroaki| Tsuda, Toshihide| Yamamoto, Eiji| Nakase, Katsumi| Doi, Hiroyuki| |
| Abstract | There have been only 2 reports of a large-scale foodborne outbreak arising from Salmonella enterica serotype Braenderup infection worldwide. On August 9, 2008, an outbreak originating in boxed lunches occurred in Okayama, Japan. We conducted a cohort study of 786 people who received boxed lunches from a particular catering company and collected 644 questionnaires (response rate:82%). Cases were defined as those presenting with diarrhea (≧4 times in 24h) or fever (≧38℃) between 12 am on August 8 and 12 am on August 14. We identified 176 cases (women/men:39/137);younger children (aged＜10 years) appeared to more frequently suffer severe symptoms. Three food items were significantly associated with higher risk of illness;tamagotoji (soft egg with mixed vegetables and meat) (relative risk (RR):11.74, 95% confidence interval (CI):2.98-46.24), pork cooked in soy sauce (RR:3.17, 95% CI:1.24-8.10), and vinegared food (RR:4.13, 95% CI:1.60-10.63). Among them, only the RR of tamagotoji was higher when we employed a stricter case definition. Salmonella Braenderup was isolated from 5 of 9 sampled cases and 6 food handlers. It is likely that unpasteurized liquid eggs contaminated by Salmonella Braenderup and used in tamagotoji caused this outbreak. |
| Keywords | boxed lunch cohort study foodborne diseases Salmonella Braenderup unpasteurized liquid eggs |
| Amo Type | Original Article |
| Publication Title | Acta Medica Okayama |
| Published Date | 2011-04 |
| Volume | volume65 |
| Issue | issue2 |
| Publisher | Okayama University Medical School |
| Start Page | 63 |
| End Page | 69 |
| ISSN | 0386-300X |
| NCID | AA00508441 |
| Content Type | Journal Article |
| language | English |
| Copyright Holders | CopyrightⒸ 2011 by Okayama University Medical School |
| File Version | publisher |
| Refereed | True |
| PubMed ID | 21519363 |
| Web of Science KeyUT | 000289818800001 |
| Author | Mizuno, Bunjiro| |
|---|---|
| Published Date | 1935-06-30 |
| Publication Title | 岡山医学会雑誌 |
| Volume | volume47 |
| Issue | issue6 |
| Content Type | Journal Article |
| Author | Ukita, Katsuzo| |
|---|---|
| Published Date | 1935-06-30 |
| Publication Title | 岡山医学会雑誌 |
| Volume | volume47 |
| Issue | issue6 |
| Content Type | Journal Article |
| Author | Hiraide, Shozo| |
|---|---|
| Published Date | 1935-06-30 |
| Publication Title | 岡山医学会雑誌 |
| Volume | volume47 |
| Issue | issue6 |
| Content Type | Journal Article |
| Author | Mizuno, Bunjiro| |
|---|---|
| Published Date | 1935-05-31 |
| Publication Title | 岡山医学会雑誌 |
| Volume | volume47 |
| Issue | issue5 |
| Content Type | Journal Article |
| Author | Kochi, Takeshi| |
|---|---|
| Published Date | 1935-04-30 |
| Publication Title | 岡山医学会雑誌 |
| Volume | volume47 |
| Issue | issue4 |
| Content Type | Journal Article |
| Author | Sudo, Gonosuke| |
|---|---|
| Published Date | 1935-03-31 |
| Publication Title | 岡山医学会雑誌 |
| Volume | volume47 |
| Issue | issue3 |
| Content Type | Journal Article |
| Author | Suga, Syûiti| |
|---|---|
| Published Date | 1935-03-31 |
| Publication Title | 岡山医学会雑誌 |
| Volume | volume47 |
| Issue | issue3 |
| Content Type | Journal Article |
| Author | Uyeno, Hiroshi| |
|---|---|
| Published Date | 1935-03-31 |
| Publication Title | 岡山医学会雑誌 |
| Volume | volume47 |
| Issue | issue3 |
| Content Type | Journal Article |
| Author | Sudo, Gonosuke| |
|---|---|
| Published Date | 1935-02-28 |
| Publication Title | 岡山医学会雑誌 |
| Volume | volume47 |
| Issue | issue2 |
| Content Type | Journal Article |
| Author | Mori, Nobutane| |
|---|---|
| Published Date | 1935-02-28 |
| Publication Title | 岡山医学会雑誌 |
| Volume | volume47 |
| Issue | issue2 |
| Content Type | Journal Article |
| Author | Yasuhara, Isao| |
|---|---|
| Published Date | 1935-02-28 |
| Publication Title | 岡山医学会雑誌 |
| Volume | volume47 |
| Issue | issue2 |
| Content Type | Journal Article |
| Author | Yasuhara, Isao| |
|---|---|
| Published Date | 1935-02-28 |
| Publication Title | 岡山医学会雑誌 |
| Volume | volume47 |
| Issue | issue2 |
| Content Type | Journal Article |
| Author | Kosaka, Hisasi| |
|---|---|
| Published Date | 1935-02-28 |
| Publication Title | 岡山医学会雑誌 |
| Volume | volume47 |
| Issue | issue2 |
| Content Type | Journal Article |
| Author | Okumura, Masanobu| |
|---|---|
| Published Date | 1935-02-28 |
| Publication Title | 岡山医学会雑誌 |
| Volume | volume47 |
| Issue | issue2 |
| Content Type | Journal Article |
| Author | Hashimoto, Ken| |
|---|---|
| Published Date | 1936-02-29 |
| Publication Title | 岡山医学会雑誌 |
| Volume | volume48 |
| Issue | issue2 |
| Content Type | Journal Article |
