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Author Momonoi, Kwanji|
Published Date 1935-07-31
Publication Title 岡山医学会雑誌
Volume volume47
Issue issue7
Content Type Journal Article
Author Takemoto, Iwao|
Published Date 1935-07-31
Publication Title 岡山医学会雑誌
Volume volume47
Issue issue7
Content Type Journal Article
Author Hirota, Teruki|
Published Date 1935-07-31
Publication Title 岡山医学会雑誌
Volume volume47
Issue issue7
Content Type Journal Article
Author Takemoto, Iwao|
Published Date 1935-07-31
Publication Title 岡山医学会雑誌
Volume volume47
Issue issue7
Content Type Journal Article
Author Ukita, Katsuzo|
Published Date 1935-07-31
Publication Title 岡山医学会雑誌
Volume volume47
Issue issue7
Content Type Journal Article
Author Hiraide, Shozo|
Published Date 1935-07-31
Publication Title 岡山医学会雑誌
Volume volume47
Issue issue7
Content Type Journal Article
Author Inaba, Minoru|
Published Date 1935-07-31
Publication Title 岡山医学会雑誌
Volume volume47
Issue issue7
Content Type Journal Article
Author Mizuno, Bunjiro|
Published Date 1936-02-29
Publication Title 岡山医学会雑誌
Volume volume48
Issue issue2
Content Type Journal Article
Author Mori, Syusai|
Published Date 1936-02-29
Publication Title 岡山医学会雑誌
Volume volume48
Issue issue2
Content Type Journal Article
Author Miyake, Mikio|
Published Date 1936-02-29
Publication Title 岡山医学会雑誌
Volume volume48
Issue issue2
Content Type Journal Article
JaLCDOI 10.18926/AMO/45274
FullText URL 65_2_143.pdf
Author Kobayashi, Yasuyuki| Saika, Takashi| Manabe, Daisuke| Nasu, Yasutomo| Kumon, Hiromi|
Abstract We analyzed the prognostic factors influencing survival after surgeries for upper urinary tract urothelial carcinoma (UUT-UC) with longer follow-up periods than in previous studies. Between January 2000 and December 2004, 386 patients underwent nephroureterectomy for UUT-UC. The data for the 221 patients with UUT-UC were retrospectively reviewed. Nine variables were evaluated for association with the survival outcomes of cause-specific survival. The prognostic significance was tested univariately with the log-rank test. The simultaneous effects of multiple prognostic factors were estimated by multiple regression analysis using the Cox proportional hazards model. The median follow-up was 38.4 months. The 5-year over all survival was 62.3%. Significant prognostic factors for disease-specific survival rate on univariate analysis were pathological stage (p0.0001), tumor grade (p0.0324), and venous invasion (p0.0001). Multivariate analysis revealed that only venous invasion was significant for disease-specific survival rate (p0.0205). Venous invasion was the only independent prognostic factor in pathologically localized UUT-UC.
Keywords nephroureterectomy transitional cell carcinoma upper urinary tract
Amo Type Corrected and Republished Article
Publication Title Acta Medica Okayama
Published Date 2011-04
Volume volume65
Issue issue2
Publisher Okayama University Medical School
Start Page 143
End Page 149
ISSN 0386-300X
NCID AA00508441
Content Type Journal Article
language English
Copyright Holders CopyrightⒸ 2011 by Okayama University Medical School
File Version publisher
Refereed True
PubMed ID 20200581
Web of Science KeyUT 000289818800011
JaLCDOI 10.18926/AMO/45270
FullText URL 65_2_113.pdf
Author Morikawa, Toshio| Yamamoto, Yuji| Miyaishi, Satoru|
Abstract We have developed a new method for sex determination based on simultaneous detection of the SRY (sex-determining region Y), STS (steroid sulfatase) and amelogenin (AMELX and AMELY) gene regions and their homologous sequences. The sex of 246 blood samples was correctly determined by this method. An AMELY-deleted male sample, which would have been erroneously considered female based solely on analysis of the amelogenin locus, was successfully identified as male by the present method. The detection limit of this method was 63 pg of genomic DNA, and the male DNA component could be detected from mixed samples having a male:female ratio as low as 1:10. This method was useful for degraded DNA and possessed the human specificity. Practical application to 35 autopsy cases is described.
Keywords sex determination SRY (sex-determining region Y) multiplex PCR forensic casework
Amo Type Original Article
Publication Title Acta Medica Okayama
Published Date 2011-04
Volume volume65
Issue issue2
Publisher Okayama University Medical School
Start Page 113
End Page 122
ISSN 0386-300X
NCID AA00508441
Content Type Journal Article
language English
Copyright Holders CopyrightⒸ 2011 by Okayama University Medical School
File Version publisher
Refereed True
PubMed ID 21519369
Web of Science KeyUT 000289818800007
JaLCDOI 10.18926/AMO/45266
FullText URL 65_2_81.pdf
Author Sasaki, Motofumi| Shikata, Kenichi| Okada, Shinichi| Miyamoto, Satoshi| Nishishita, Shingo| Usui Kataoka, Hitomi| Sato, Chikage| Wada, Jun| Ogawa, Daisuke| Makino, Hirofumi|
Abstract Glomerular hyperfiltration is a common pathway leading to glomerulosclerosis in various kinds of kidney diseases. The 5/6 renal ablation is an established experimental animal model for glomerular hyperfiltration. On the other hand, low-grade inflammation is also a common mechanism for the progression of kidney diseases including diabetic nephropathy and atherosclerosis. Here we analyzed the gene expression profile in the remnant kidney tissues of 5/6 nephrectomized mice using a DNA microarray system and compared it with that of sham-operated control mice. The 5/6 nephrectomized mice showed glomerular hypertrophy and an increase in the extracellular matrix in the glomeruli. DNA microarray analysis indicated the up-regulated expression of various kinds of genes related to the inflammatory process in remnant kidneys. We confirmed the up-regulated expression of platelet factor-4, and monocyte chemoattractant protein-1, 2, and 5 in remnant kidneys by RT-PCR. The current results suggest that the inflammatory process is involved in the progression of glomerulosclerosis and is a common pathway of the pathogenesis of kidney disease.
Keywords kidney inflammation chemokine
Amo Type Original Article
Publication Title Acta Medica Okayama
Published Date 2011-04
Volume volume65
Issue issue2
Publisher Okayama University Medical School
Start Page 81
End Page 89
ISSN 0386-300X
NCID AA00508441
Content Type Journal Article
language English
Copyright Holders CopyrightⒸ 2011 by Okayama University Medical School
File Version publisher
Refereed True
PubMed ID 21519365
Web of Science KeyUT 000289818800003
JaLCDOI 10.18926/AMO/45264
FullText URL 65_2_63.pdf
Author Mizoguchi, Yoshinori| Suzuki, Etsuji| Tsuchida, Hiroaki| Tsuda, Toshihide| Yamamoto, Eiji| Nakase, Katsumi| Doi, Hiroyuki|
Abstract There have been only 2 reports of a large-scale foodborne outbreak arising from Salmonella enterica serotype Braenderup infection worldwide. On August 9, 2008, an outbreak originating in boxed lunches occurred in Okayama, Japan. We conducted a cohort study of 786 people who received boxed lunches from a particular catering company and collected 644 questionnaires (response rate:82%). Cases were defined as those presenting with diarrhea (≧4 times in 24h) or fever (≧38℃) between 12 am on August 8 and 12 am on August 14. We identified 176 cases (women/men:39/137);younger children (aged<10 years) appeared to more frequently suffer severe symptoms. Three food items were significantly associated with higher risk of illness;tamagotoji (soft egg with mixed vegetables and meat) (relative risk (RR):11.74, 95% confidence interval (CI):2.98-46.24), pork cooked in soy sauce (RR:3.17, 95% CI:1.24-8.10), and vinegared food (RR:4.13, 95% CI:1.60-10.63). Among them, only the RR of tamagotoji was higher when we employed a stricter case definition. Salmonella Braenderup was isolated from 5 of 9 sampled cases and 6 food handlers. It is likely that unpasteurized liquid eggs contaminated by Salmonella Braenderup and used in tamagotoji caused this outbreak.
Keywords boxed lunch cohort study foodborne diseases Salmonella Braenderup unpasteurized liquid eggs
Amo Type Original Article
Publication Title Acta Medica Okayama
Published Date 2011-04
Volume volume65
Issue issue2
Publisher Okayama University Medical School
Start Page 63
End Page 69
ISSN 0386-300X
NCID AA00508441
Content Type Journal Article
language English
Copyright Holders CopyrightⒸ 2011 by Okayama University Medical School
File Version publisher
Refereed True
PubMed ID 21519363
Web of Science KeyUT 000289818800001
Author Mizuno, Bunjiro|
Published Date 1935-06-30
Publication Title 岡山医学会雑誌
Volume volume47
Issue issue6
Content Type Journal Article
Author Koizumi, Michinori|
Published Date 1935-06-30
Publication Title 岡山医学会雑誌
Volume volume47
Issue issue6
Content Type Journal Article
Author Danjho, Junzo|
Published Date 1935-06-30
Publication Title 岡山医学会雑誌
Volume volume47
Issue issue6
Content Type Journal Article
Author Ukita, Katsuzo|
Published Date 1935-06-30
Publication Title 岡山医学会雑誌
Volume volume47
Issue issue6
Content Type Journal Article
Author Hasegawa, Tsuneji|
Published Date 1935-06-30
Publication Title 岡山医学会雑誌
Volume volume47
Issue issue6
Content Type Journal Article
Author Yasuhara, Setutaro|
Published Date 1935-06-30
Publication Title 岡山医学会雑誌
Volume volume47
Issue issue6
Content Type Journal Article