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Author Osunleke, Ajiboye Saheeb|
Published Date 2010-09-30
Publication Title
Content Type Thesis or Dissertation
Author Nan, Bin Mad Sahar|
Published Date 2010-09-30
Publication Title
Content Type Thesis or Dissertation
Author Walaa, Abdel Mohsen Abdel Salam Hassan|
Published Date 2010-09-30
Publication Title
Content Type Thesis or Dissertation
Author Mohamed, Abdel-Malek Abd Allah Orabi|
Published Date 2010-09-30
Publication Title
Content Type Thesis or Dissertation
Author Zhang, Jiyong|
Published Date 2010-09-30
Publication Title
Content Type Thesis or Dissertation
Author Agaoka, Yoshio|
Published Date 2011-01
Publication Title Mathematical Journal of Okayama University
Volume volume53
Issue issue1
Content Type Journal Article
JaLCDOI 10.18926/mjou/41406
Author Hai, Pham Viet| Thanh, Le Ngoc|
Published Date 2011-01
Publication Title Mathematical Journal of Okayama University
Volume volume53
Issue issue1
Content Type Journal Article
JaLCDOI 10.18926/mjou/41405
Author Malonek, Helmuth R.| Peña, Dixan Peña| Sommen, Frank|
Published Date 2011-01
Publication Title Mathematical Journal of Okayama University
Volume volume53
Issue issue1
Content Type Journal Article
JaLCDOI 10.18926/mjou/41404
Author Kitayama, Hidetaka|
Published Date 2011-01
Publication Title Mathematical Journal of Okayama University
Volume volume53
Issue issue1
Content Type Journal Article
JaLCDOI 10.18926/mjou/41403
Author Yoshino, Yuji| Yoshizawa, Takeshi|
Published Date 2011-01
Publication Title Mathematical Journal of Okayama University
Volume volume53
Issue issue1
Content Type Journal Article
JaLCDOI 10.18926/mjou/41402
Author Kamoi, Yuji|
Published Date 2011-01
Publication Title Mathematical Journal of Okayama University
Volume volume53
Issue issue1
Content Type Journal Article
JaLCDOI 10.18926/mjou/41401
Author Baba, Yoshitomo| Yamazaki, Takeshi|
Published Date 2011-01
Publication Title Mathematical Journal of Okayama University
Volume volume53
Issue issue1
Content Type Journal Article
JaLCDOI 10.18926/mjou/41400
Author Yang, Xiaoyan| Liu, Zhongkui|
Published Date 2011-01
Publication Title Mathematical Journal of Okayama University
Volume volume53
Issue issue1
Content Type Journal Article
JaLCDOI 10.18926/mjou/41399
Author Najman, Filip|
Published Date 2011-01
Publication Title Mathematical Journal of Okayama University
Volume volume53
Issue issue1
Content Type Journal Article
JaLCDOI 10.18926/mjou/41398
Author Lee, Min Ho|
Published Date 2011-01
Publication Title Mathematical Journal of Okayama University
Volume volume53
Issue issue1
Content Type Journal Article
JaLCDOI 10.18926/mjou/41397
Author Dougherty, Steven T.| Liu, Hongwei| Park, Young Ho|
Published Date 2011-01
Publication Title Mathematical Journal of Okayama University
Volume volume53
Issue issue1
Content Type Journal Article
JaLCDOI 10.18926/mjou/41396
Author Tamura, Hideo|
Published Date 2011-01
Publication Title Mathematical Journal of Okayama University
Volume volume53
Issue issue1
Content Type Journal Article
JaLCDOI 10.18926/mjou/41395
JaLCDOI 10.18926/AMO/41327
FullText URL 64_6_407.pdf
Author Ogata, Sho| Horio, Takuya| Sugiura, Yoshiaki| Shimazaki, Hideyuki| Saito, Hiroki| Aiko, Satoshi| Nakanishi, Kuniaki| Kawai, Toshiaki|
Abstract Sarcoidosis is a systemic granulomatous inflammation of unknown etiology, and seems to involve the liver parenchyma in most cases. However, sarcoidosis-associated hepatocellular carcinoma is rare. We report here a case in which a hepatocellular carcinoma occurred within the liver, which was probably involved as a result of systemic sarcoidosis. A 57-year-old Japanese man had been followed up for 2 years because of diabetic nephropathy and sarcoidosis. On admission for pneumonia, imaging studies revealed an unexpected hepatic tumor. Histology revealed a hepatocellular carcinoma accompanied by T-lymphocytic infiltration and marked granulomatous inflammation, which was surrounding some tumor nodules. The background liver parenchyma exhibited a moderate degree of fibrosis with granulomatous inflammation. The patient had no other apparent liver disease such as viral hepatitis, steatohepatitis, or primary biliary cirrhosis. Therefore, in the present case, sarcoidosis may be considered the probable background etiology for hepatocarcinogenesis.
Keywords granuloma hepatocellular carcinoma lymphocytic infiltration sarcoidosis
Amo Type Case Report
Publication Title Acta Medica Okayama
Published Date 2010-12
Volume volume64
Issue issue6
Publisher Okayama University Medical School
Start Page 407
End Page 410
ISSN 0386-300X
NCID AA00508441
Content Type Journal Article
language English
Copyright Holders Okayama University Medical School
File Version publisher
Refereed True
PubMed ID 21173811
Web of Science KeyUT 000285664200008
JaLCDOI 10.18926/AMO/41326
FullText URL 64_6_399.pdf
Author Chang, Chin-Hsien| Chen, Kuo-Ti| Lee, Tsong-Hai| Wang, Chao-Hung| Kuo, Yi-Wen| Chiu, Ya-Huang| Hsieh, Ching-Liang| Wu, Chang-Jer| Chang, Yen-Lin|
Abstract Vascular endothelial damage has been found to be associated with thrombus formation, which is considered to be a risk factor for cardiovascular disease. A diet of natto leads to a low prevalence of cardiovascular disease. The aim of the present study was to investigate the effects of natto extract on vascular endothelia damage with exposure to laser irradiation. Endothelial damage both in vitro and in vivo was induced by irradiation of rose bengal using a DPSS green laser. Cell viability was determined by MTS assay, and the intimal thickening was verified by a histological approach. The antioxidant content of natto extract was determined for the free radical scavenging activity. Endothelial cells were injured in the presence of rose bengal irradiated in a dose-dependent manner. Natto extract exhibits high levels of antioxidant activity compared with purified natto kinase. Apoptosis of laser-injured endothelial cells was significantly reduced in the presence of natto extract. Both the natto extract and natto kinase suppressed intimal thickening in rats with endothelial injury. The present findings suggest that natto extract suppresses vessel thickening as a synergic effect attributed to its antioxidant and anti-apoptosis properties.
Keywords laser irradiation natto extract thrombolysis thrombosis
Amo Type Original Article
Publication Title Acta Medica Okayama
Published Date 2010-12
Volume volume64
Issue issue6
Publisher Okayama University Medical School
Start Page 399
End Page 406
ISSN 0386-300X
NCID AA00508441
Content Type Journal Article
language English
Copyright Holders Okayama University Medical School
File Version publisher
Refereed True
PubMed ID 21173810
Web of Science KeyUT 000285664200007