result 868 件
| JaLCDOI | 10.18926/11757 |
|---|---|
| Title Alternative | Lipid Peroxides (TBA reactive substances)and Fatty Acid Compositions in Mouse Serum with Whole-body Irradiation and in Tumor-bearing Mouse Serum with Local Irradiation |
| FullText URL | 001_029_037.pdf |
| Author | Yamamoto, Goki| |
| Abstract | Effects of irradiation on lipid peroxides of mouse serum, Ehrlich solid tumor-bearing mouse serum, which tomor cells were transplanted to the leg, and its tumor tissue were studied by a thiobarbituric acid (TBA) color reaction in the acetic acid condition with (Fe-TBA value) or without (TBA value) ferrous ammonium sulfate. TBA reactive substances were caluculated into the amount of malondialdehyde. Besides, fatty acid and lipid compositions were analyzed as a substrates. Irradiated samples were isolated at 3 days after irradiations. The TBA value of normal mouse serum was expressed 17nmoles/ml of serum, and Fe-TBA value gave 2.4-fold of the TBA value. Although an increase TBA value was not observed by whole-body irradiation, a significant increase of Fe-TBA value was measured, indicating 2.5-fold at 10Gy exposure compared with the normal Fe-TBA value, and 5.5-fold with the TBA value. The TBA value of tumor-bearing mouse serum was 14nmoles/ml as a low rate to that of normal serum, but the Fe-TBA value gave same magnification of that of normal one. The TBA value of tumor-bearing mouse serum was not changed by the local irradiation to the tumor region of leg, but the Fe-TBA value was increased 2.8 and 4.4 times at 10Gy and 20Gy exposures, respectively, comparing with the non-irradiated one, and 7.7 and 10.5 times with the TBA value, respectively. The TBA value of solid tumor homogenate exhibited 1.16nmoles/mg of protein, and the Fe-TBA value, pointed out 5 times as much as the TBA value. Both values slightly increased by the irradiation. These facts suggest that a shift of TBA value of serum hard to get, but Fe-TBA value of serum distinctly increases by the irradiation. The fatty acid composition of mouse serum lipids showed an increment of relative percentages of linoleic and arachidonic acids by the whole-body irradiation. The relative percentage of fatty acid compositon of lipids from solid tumor-bearing mouse serum was similar tendency to that of normal one, and the local exposure to the tumor part was not affected the each percentage. The percentage of high unsaturated fatty acid of tumor lipids similar to that of serum lipids, and a decrease of the percentage of arachidonic acid was accounted by the irradiation. In relative percentages of lipid compositions, the percentage of choleste rolester of serum lipids increased by the whole-body irradiation, and that of phospholipid fraction was not changed. In the case of tumor-bearing mouse serum lipids, an increment of the percentage of cholesterolester was obtained as compared with that of normal serum lipids, and this percentage decreased by the local irradiation to tumor part with an increment of the percentage of phospholipid. The percentage of phospholipid in tumor lipids had decreased by the irradiation. The facts suggest that a cause of the increased Fe-TBA value of tumor-bearing mouse serum by the irradiation to tumor is due to the release of peroxidizable phospholipid into serum from the damaged menbranes of tumor cells at large doses to exposure. |
| Keywords | Lipid peroxides Irradiation Mouse serum Tumor-bearing mouse serum Fatty acid composition |
| Publication Title | 岡山大学医療技術短期大学部紀要 |
| Published Date | 1991-03-25 |
| Volume | volume1 |
| Start Page | 29 |
| End Page | 37 |
| ISSN | 0917-4494 |
| language | Japanese |
| File Version | publisher |
| NAID | 120002313903 |
| JaLCDOI | 10.18926/11734 |
|---|---|
| Title Alternative | Analysis of three cases of renal transplant recipients whose feelings about life have become negative after transplantation |
| FullText URL | 010_1_051_056.pdf |
| Author | Watanabe, Kumi| Hayashi, Yuko| Nakanishi, Yoshiko| Kanao, Naomi| Hosina, Eiko| |
| Abstract | 筆者らは，林が作成した看護援助モデルに基づき，腎移植者への効果的な看護介入についての検討を行っている。その一環として，今回，腎移植を受けた119名を対象に，QOLや移植前と現在の人生に対する受けとめ方について調査した。人生に対する受けとめ方の移植前後の変化を分析したところ，ほぼ全数に近い腎移植者が移植前と比べよい状態であると受けとめていたが，3事例において受けとめ方が低下していた。そこで，この3事例に着目し，これらの事例が日常生活の中で不満を抱いている事柄を分析した。その結果，移植後に人生に対する受けとめ方が低下した3事例が抱く不満は，1．腎臓・健康などの身体状況，2．家庭環境，3．医療・友人・他人からのサポート，4．家族や社会の中で役割を果たす能力の4カテゴリーに分類された。移植後の人生の受けとめ方の否定的変化には，上記の4カテゴリーに対して抱く不満が影響していることが推測され，腎移植後の看護介入を検討する上で考慮すべき点であることが明らかになった。 |
| Keywords | QOL (quality of life) 腎移植 腎移植者 (renal transplant recipient) 看護 (nuising approach) |
| Publication Title | 岡山大学医学部保健学科紀要 |
| Published Date | 1999-12-20 |
| Volume | volume10 |
| Issue | issue1 |
| Start Page | 51 |
| End Page | 56 |
| ISSN | 1345-0948 |
| language | Japanese |
| File Version | publisher |
| NAID | 120002313642 |
| Author | Sakoda, Yukimi| |
|---|---|
| Published Date | 2007-03-23 |
| Publication Title | |
| Content Type | Thesis or Dissertation |
| JaLCDOI | 10.18926/11717 |
|---|---|
| Title Alternative | 因果関係モデルによる腎移植レシピエントのQOLの分析 |
| FullText URL | 010_2_077_084.pdf |
| Author | Hayashi, Yuko| Kanao, Naomi| Nakanishi, Yoshiko| Watanabe, Kumi| Hoshina, Eiko| |
| Abstract | The purpose of this study is to analyze the structural relationship among the components of quality of life of kidney transplant recipients by using a causal model. The subjects were 329 recipients who had regular checks-up following transplantation in seven general hospitals in Tokyo, Gunma, Aichi, Okayama, and Hiroshima, and agreed to participate in this study. Ferrans and Powers's Quality of Life - Index Kidney Transplant version was used to measure perceived quality of life. The self-administered questionnaires were handed over to the subjects, who completed the instrument on the spot. After that, the answers were collected immediately. The factor analysis and the covariance structure analysis were used to make clear the structural relationship among the components of quality of life. The results of data analysis were as follows : (1) Five components of quality of life were extracted ; socio-economic functioning, family ties, emotional support, physical health, and peace & happiness. (2) The scores in the family ties dimension and the physical health dimension were higher than in the others, and the score in the socio-economic functioning dimension was the lowest. (3) The physical health showed the starting point in a causal model. (4) The physical health influenced the family ties and the socio-economic functioning. (5) The socio-economic functioning strongly influenced the peace & happiness and the emotional support. (6) The family ties influenced the socio-economic functioning, the emotional support, and the peace & happiness. Therefore, it was conceivable that it was particularly important to make approaches for the physical health, the family ties, and the socio-economic functioning dimensions to improve quality of life. |
| Keywords | 腎移植のレシピエント (kidney transplant recipient) QOLの構成要素 (components of quality of life) QOLのパスダイアグラム (path diagram of quality of life) |
| Publication Title | 岡山大学医学部保健学科紀要 |
| Published Date | 2000-03-24 |
| Volume | volume10 |
| Issue | issue2 |
| Start Page | 77 |
| End Page | 84 |
| ISSN | 1345-0948 |
| language | English |
| File Version | publisher |
| NAID | 120002313658 |
| JaLCDOI | 10.18926/11693 |
|---|---|
| Title Alternative | Hyhrid vascular grafts and one of our approaches |
| FullText URL | 061_114_122.pdf |
| Author | Noishiki, Yasuharu| |
| Abstract | 人工血管により高度な機能をもたす目的で，ハイブリット化が今日進められるようになってきた。この背景について説明するとともに，我々の独自に行っているハイブリット型人工血管作成の方法およびその成果について報告する。その具体的方法としては以下の通りである。末梢静脈小片を勇刀にて細切したのち，約20ccの生理的食塩水に入れて静脈組織細切片浮遊液を作った。次に高有孔性人工血管の一端より吸引管を挿入し，これを作成した液に入れ，吸引によって組織片を外側から人工血管壁に絡ませた。次に新鮮な血液を注ぎ，組織片をさらに固着させた。成犬胸部下行大動脈へこのような処理をしたポリエステル布製人工血管を植え込んだところ，植え込み5日目に新生血管壁内部に無数の内皮細胞の増殖像がみられ，35日目の例では吻合部はもとより，人工血管の中央部ですら内皮細胞による完全な被覆を認めた。 以上のような方法で新生血管壁が容易に形成されることが判明したことより，今後，他の人工臓器分野でもハイブリット化が予測される。 |
| Keywords | 人工血管 (Vascular graft) ハイブリット (Hybrid) 新生内膜 (Neointima) 内皮細胞 (Endothelial cell) 自家移植 (Autologous transplantation) |
| Publication Title | 環境病態研報告 |
| Published Date | 1990-09 |
| Volume | volume61 |
| Start Page | 114 |
| End Page | 122 |
| ISSN | 0913-3771 |
| language | Japanese |
| File Version | publisher |
| NAID | 120002313776 |
| JaLCDOI | 10.18926/11687 |
|---|---|
| Title Alternative | New trend of the development of vascular prostheses |
| FullText URL | 061_098_113.pdf |
| Author | Noishiki, Yasuharu| |
| Abstract | 人工血管の開発研究における動向について，我々の行ってきた研究をまじえて世界の動きを解析した。近年の砺究の流れは過去1世紀にわたる試行錯誤の上にあって，さらに大きく揺れ動いている。人工血管の内面に必要な抗血栓性の獲得においても，設計者によって考えを異にし，米国では，人工心臓に用いる抗血栓性合性高分子材料をもってそれに当てようとしているものが多い。我々はあくまで宿主のもつ諸機能を引き出し，自然の動きの一つとしての治癒を無理なく導いて，内皮細胞によって内面を覆わせる方法を採用している。そのいくつかの例として，超極細ポリエステル繊維製人工血管，結合組織管，バイオマトリックス人工血管，ヘパリン化生体組織由来人工血管，成長できる人工血管などについて解説した。 |
| Keywords | 人工血管 (Vascular prosthesis) 新生内膜 (Neointima) 内皮細胞 (Endothelial cells) 抗血栓性 (Antithrombogenicity) |
| Publication Title | 環境病態研報告 |
| Published Date | 1990-09 |
| Volume | volume61 |
| Start Page | 98 |
| End Page | 113 |
| ISSN | 0913-3771 |
| language | Japanese |
| File Version | publisher |
| NAID | 120002313859 |
| JaLCDOI | 10.18926/11683 |
|---|---|
| Title Alternative | The reality investigation of stresses which the new figure nurses employed after one month hold |
| FullText URL | 011_2_071_076.pdf |
| Author | Mori, Keiko| |
| Abstract | 看護教育カリキュラムの改正により，臨床での実習時間はますます減る傾向にある。一方，臨床現場では，医療の高度化，複雑化が進み，看護基礎教育と現場のギャップは大きくなる傾向にある。今回38名の新人看護婦にアンケート調査を行い，新人看護婦の抱えるストレスについて明らかにした。その結果，新人看護婦の抱えるストレスは，看護技術に関するストレスが最も多く（94％），ついで，3交代勤務による不規則な生活（14％），患者とのコミュニケーション（11％）であった。この結果には教育課程の違いによる差は認められなかった。多くのストレスの中で働く新人看護婦は，32.3％が，体調についてあまりよくない，あるいは良くないと回答していた。また，様々なストレスにより，就職後1ヶ月で退職を考えているものが6名（17.6％）いた。看護婦になってよかったと答えたものは8名（82％）あり，その多くが，患者との関わりがうまくいったときにそのように感じていた。新人看護婦が，今後の看護基礎教育に望むことは，技術面の体験をさらに増やすこと，移植医療，ME機器の取り扱いなどであった。 |
| Keywords | 新人看護婦 (The new figure nurse) ストレス (stress) リアリティーショック (reality shock) |
| Publication Title | 岡山大学医学部保健学科紀要 |
| Published Date | 2001-03-24 |
| Volume | volume11 |
| Issue | issue2 |
| Start Page | 71 |
| End Page | 76 |
| ISSN | 1345-0948 |
| language | Japanese |
| File Version | publisher |
| NAID | 120002313522 |
| Author | Tomiyama, Koji| |
|---|---|
| Published Date | 2007-03-23 |
| Publication Title | |
| Content Type | Thesis or Dissertation |
| Author | Okazaki, Mikio| |
|---|---|
| Published Date | 2007-03-23 |
| Publication Title | |
| Content Type | Thesis or Dissertation |
| Author | Goto, Tanjuro| Yamato, Chie| Kageyama, Yoshihiro| Konishi, Kuniyoshi| |
|---|---|
| Published Date | 1996-02-01 |
| Publication Title | 岡山大学農学部学術報告 |
| Volume | volume85 |
| Issue | issue1 |
| Content Type | Departmental Bulletin Paper |
| Author | Goto, Tanjuro| Kageyama, Yoshihiro| Konishi, Kuniyoshi| |
|---|---|
| Published Date | 1997-02 |
| Publication Title | 岡山大学農学部学術報告 |
| Volume | volume86 |
| Issue | issue1 |
| Content Type | Departmental Bulletin Paper |
| Author | Goto, Tanjuro| Masaoka, Keishi| Kageyama, Yoshihiro| Konishi, Kuniyoshi| |
|---|---|
| Published Date | 1998-02 |
| Publication Title | 岡山大学農学部学術報告 |
| Volume | volume87 |
| Issue | issue1 |
| Content Type | Departmental Bulletin Paper |
| Author | Goto, Tanjuro| Kageyama, Yoshihiro| Konishi, Kuniyoshi| |
|---|---|
| Published Date | 1999-02 |
| Publication Title | 岡山大学農学部学術報告 |
| Volume | volume88 |
| Issue | issue1 |
| Content Type | Departmental Bulletin Paper |
| Author | Sugimoto, Ryujiro| |
|---|---|
| Published Date | 2006-12-31 |
| Publication Title | |
| Content Type | Thesis or Dissertation |
| Author | Kato, Gentaro| |
|---|---|
| Published Date | 2006-12-31 |
| Publication Title | |
| Content Type | Thesis or Dissertation |
| Author | Muraoka, Ken-ichiro| |
|---|---|
| Published Date | 2006-06-30 |
| Publication Title | |
| Content Type | Thesis or Dissertation |
| Author | 陳 勇| |
|---|---|
| Published Date | 2006-03-24 |
| Publication Title | |
| Content Type | Thesis or Dissertation |
| Author | Matsuoka, Ken-ichi| |
|---|---|
| Published Date | 2006-03-24 |
| Publication Title | |
| Content Type | Thesis or Dissertation |
| Author | Aokage, Keiju| |
|---|---|
| Published Date | 2006-03-24 |
| Publication Title | |
| Content Type | Thesis or Dissertation |
| Author | Goto, Tanjuro| Yoshida, Yuichi| |
|---|---|
| Published Date | 2003-02 |
| Publication Title | 岡山大学農学部学術報告 |
| Volume | volume92 |
| Issue | issue1 |
| Content Type | Departmental Bulletin Paper |
