result 14822 件
| Author | ODA, Makiko| KOLJONEN, Saija| ISHIOKA, Fumio| ALHO, Petteri| SUITO, Hiroshi| HUTTULA, Timo| KURIHARA, Koji| |
|---|---|
| Published Date | 2014-06 |
| Publication Title | SYKE-OU Project Report |
| Content Type | Research Paper |
| Author | MANO, Akiko| MALVE, Olli| KOPONEN, Sampsa| KALLIO, Kari| TASKINEN, Antti| ROPPONEN, Janne| JUNTUNEN, Janne| LIUKKO, Ninni| |
|---|---|
| Published Date | 2014-06 |
| Publication Title | SYKE-OU Project Report |
| Content Type | Research Paper |
| Author | MANO, Akiko| SHUKU, Takayuki| |
|---|---|
| Published Date | 2014-06 |
| Publication Title | SYKE-OU Project Report |
| Content Type | Research Paper |
| Author | MORIFUJI, Shinya| SUITO, Hiroshi| ROPPONEN, Janne| OKUBO, Kenji| |
|---|---|
| Published Date | 2014-06 |
| Publication Title | SYKE-OU Project Report |
| Content Type | Research Paper |
| Author | NISHIMURA, Shin-ichi| OKUBO, Kenji| MORITA, Hidenori| KOSKIAHO, Jari| TATTARI, Sirrka| |
|---|---|
| Published Date | 2014-06 |
| Publication Title | SYKE-OU Project Report |
| Content Type | Research Paper |
| Author | OKUBO, Kenji| KOSKIAHO, Jari| VENTELÄ, Anne-Mari| HUTTULA, Timo| |
|---|---|
| Published Date | 2014-06 |
| Publication Title | SYKE-OU Project Report |
| Content Type | Research Paper |
| Author | ROPPONEN, Janne| HUTTULA, Timo| |
|---|---|
| Published Date | 2014-06 |
| Publication Title | SYKE-OU Project Report |
| Content Type | Research Paper |
| Author | WU, Ting Feng| OKUBO, Kenji| HUTTULA, Timo| ROPPONEN, Janne| |
|---|---|
| Published Date | 2014-06 |
| Publication Title | SYKE-OU Project Report |
| Content Type | Research Paper |
| Author | OKUBO, Kenji| HUTTULA, Timo| SUITO, Hiroshi| ROPPONEN, Janne| MANO, Akiko| NAKAZAWA, Takashi| |
|---|---|
| Published Date | 2014-06 |
| Publication Title | SYKE-OU Project Report |
| Content Type | Research Paper |
| Author | MOROIZUMI, Toshitsugu| ITO, Naoya| KOSKIAHO, Jari| TATTARI, Sirkka| |
|---|---|
| Published Date | 2014-06 |
| Publication Title | SYKE-OU Project Report |
| Content Type | Research Paper |
| Author | SUITO, Hiroshi| KOBAYASHI, Mika| LIUKKO, Ninni| HUTTULA, Timo| |
|---|---|
| Published Date | 2014-06 |
| Publication Title | SYKE-OU Project Report |
| Content Type | Research Paper |
| Author | HUTTULA, Timo| LIUKKO, Ninni| |
|---|---|
| Published Date | 2014-06 |
| Publication Title | SYKE-OU Project Report |
| Content Type | Research Paper |
| Author | HUTTULA, Timo| SUITO, Hiroshi| |
|---|---|
| Published Date | 2014-06 |
| Publication Title | SYKE-OU Project Report |
| Content Type | Research Paper |
| Author | SUITO, Hiroshi| HUTTULA, Timo| |
|---|---|
| Published Date | 2014-06 |
| Publication Title | SYKE-OU Project Report |
| Content Type | Research Paper |
| JaLCDOI | 10.18926/AMO/52660 |
|---|---|
| FullText URL | 68_3_183.pdf |
| Author | Hasegawa, Kenjiro| Namba, Yuzaburo| Kimata, Yoshihiro| |
| Abstract | Since 2001, we have been performing phalloplasty with a radial forearm free flap as the flap of first choice in female-to-male transsexuals (FTMTS). In the present case, a 22-year-old FTMTS with a negative Allen test, we achieved good results by performing phalloplasty with an innervated island pedicled anterolateral thigh flap using the “tube within a tube” technique, in which the penis and urethra are constructed with a single flap. As compared to a forearm flap, use of an innervated islandpedicled flap may have the following advantages in phalloplasty: 1) no need for a microsurgical technique; 2) no scars at noticeable sites; 3) small functional loss in the flap donor area; 4) no sacrifice of major blood vessels. Thus, this technique seems to be a useful clinical alternative for phallic reconstruction. |
| Keywords | gender identity disorder sex reassignment surgery (SRS) phalloplasty |
| Amo Type | Corrected and Republished Article |
| Publication Title | Acta Medica Okayama |
| Published Date | 2014-06 |
| Volume | volume68 |
| Issue | issue3 |
| Publisher | Okayama University Medical School |
| Start Page | 183 |
| End Page | 190 |
| ISSN | 0386-300X |
| NCID | AA00508441 |
| Content Type | Journal Article |
| language | English |
| Copyright Holders | CopyrightⒸ 2014 by Okayama University Medical School |
| File Version | publisher |
| Refereed | True |
| PubMed ID | 24945633 |
| Web of Science KeyUT | 000337655600009 |
| Related Url | http://doi.org/10.18926/AMO/51869 |
| JaLCDOI | 10.18926/AMO/52659 |
|---|---|
| FullText URL | 68_3_177.pdf |
| Author | Mizuno, Shoma| Ota, Seisuke| Tanaka, Takehiro| Shiomi, Kohei| Matsumura, Tadashi| Kishimoto, Nobuyasu| |
| Abstract | Primary tracheal malignant lymphoma is a rare disease;only 30 cases have been reported to date. A 73-year-old Japanese man with a history of asbestos exposure was undergoing biannual chest computed tomography (CT) twice a year as a routine procedure for those previously exposed to asbestos. He had been smoking since the age of 32. In September 2010, chest CT during this regular checkup revealed a polypoid lesion in his trachea and pleural plaques, which were suspected to be caused by asbestos. Bronchoscopy performed in October revealed a polypoid lesion with granules and nodules in the trachea. A diagnosis of non-Hodgkin lymphoma (NHL) and extranodal marginal-zone B-cell lymphoma of mucosa-associated lymphoid tissue (MALT) was confirmed by histological analysis of the biopsy specimens. To our knowledge, this is the first case of primary tracheal lymphoma associated with a history of asbestos exposure. Several reports have documented no correlation between asbestos and malignant lymphoma. In addition, the correlation between smoking and NHL is weak. Although we cannot exclude the possibility of a simple coincidence of asbestos, smoking, and tracheal lymphoma, this case suggests that asbestos and smoking might have multiplicative effects in the development or progression of tracheal lymphoma. |
| Keywords | bronchus-associated lymphoid tissue tracheal lymphoma regular checkup asbestos smoking |
| Amo Type | Case Report |
| Publication Title | Acta Medica Okayama |
| Published Date | 2014-06 |
| Volume | volume68 |
| Issue | issue3 |
| Publisher | Okayama University Medical School |
| Start Page | 177 |
| End Page | 181 |
| ISSN | 0386-300X |
| NCID | AA00508441 |
| Content Type | Journal Article |
| language | English |
| Copyright Holders | CopyrightⒸ 2014 by Okayama University Medical School |
| File Version | publisher |
| Refereed | True |
| PubMed ID | 24942797 |
| Web of Science KeyUT | 000337655600008 |
| JaLCDOI | 10.18926/AMO/52658 |
|---|---|
| FullText URL | 68_3_171.pdf |
| Author | Hagiya, Hideharu| Matsumoto, Mitsuaki| Yamasawa, Takahiko| Haruki, Yuto| Otsuka, Fumio| |
| Abstract | A 79-year-old man who had undergone a right femoropopliteal (FP) bypass operation 6 weeks previously was diagnosed with vascular graft infection caused by Staphylococcus lugdunensis. Another FP bypass operation was performed, with long-term administration of antibiotics, and the patient eventually recovered well without any recurrences for over 2 years. Although S. lugdunens is classified as coagulase-negative Staphylococcus, its pathogenicity has been reported to be equal to that of S. aureus. Based on the literature review, the organism characteristically colonizes the inguinal area of human skin;thus, operations such as FP bypass grafting may place patients at a relatively high risk for infection by S. lugdunensis, a potentially high-pathogenicity organism. |
| Keywords | coagulase-negative Staphylococcus (CNS) femoropopliteal (FP) bypass Staphylococcus lugdunensis vacuum-assisted closure (VAC) therapy vascular graft infection (VGI) |
| Amo Type | Case Report |
| Publication Title | Acta Medica Okayama |
| Published Date | 2014-06 |
| Volume | volume68 |
| Issue | issue3 |
| Publisher | Okayama University Medical School |
| Start Page | 171 |
| End Page | 175 |
| ISSN | 0386-300X |
| NCID | AA00508441 |
| Content Type | Journal Article |
| language | English |
| Copyright Holders | CopyrightⒸ 2014 by Okayama University Medical School |
| File Version | publisher |
| Refereed | True |
| PubMed ID | 24942796 |
| Web of Science KeyUT | 000337655600007 |
| JaLCDOI | 10.18926/AMO/52657 |
|---|---|
| FullText URL | 68_3_163.pdf |
| Author | Tate, Genshu| Kishimoto, Koji| Mitsuya, Toshiyuki| |
| Abstract | The aim of the present study is to address whether the molecular pathogenesis is identical among multiple basal cell carcinomas (BCCs) present in the same nevoid basal cell carcinoma syndrome (NBCCS) patient. Patient 1 is a 61-year-old (yo) Japanese female whose clinical characteristics and findings of a genetic analysis of PTCH1 have been previously described. Patient 2 is patient 1ʼs 64-yo sister who also suffered from NBCCS with a single base deletion at nucleotide 2613 in exon 16 (c.2613delC) in one PTCH1 allele. Thirteen and 3 independent specimens of BCC were applied for a molecular analysis of loss of heterozygosity (LOH) in PTCH1 in patients 1 and 2, respectively. Of particular note is that all BCC specimens examined showed a loss of the wild-type allele of exon 16 in PTCH1, thus indicating that LOH results in the biallelic disruption of PTCH1 in multiple BCCs that develop in an age- and location-independent manner in the same patient. These results indicate that the germline single base deletion of PTCH1 (c.2613 delC) is a first hit and the LOH of the wild-type allele is a second hit, implying that all 16 BCCs detected in these NBCCS sisters fit the standard two-hit model. |
| Keywords | biallelic disruption hedgehog nevoid basal cell carcinoma syndrome Patched 1 two-hit model |
| Amo Type | Original Article |
| Publication Title | Acta Medica Okayama |
| Published Date | 2014-06 |
| Volume | volume68 |
| Issue | issue3 |
| Publisher | Okayama University Medical School |
| Start Page | 163 |
| End Page | 170 |
| ISSN | 0386-300X |
| NCID | AA00508441 |
| Content Type | Journal Article |
| language | English |
| Copyright Holders | CopyrightⒸ 2014 by Okayama University Medical School |
| File Version | publisher |
| Refereed | True |
| PubMed ID | 24942795 |
| Web of Science KeyUT | 000337655600006 |
| JaLCDOI | 10.18926/AMO/52656 |
|---|---|
| FullText URL | 68_3_157.pdf |
| Author | Oozawa, Susumu| Sano, Shunji| Nishibori, Masahiro| |
| Abstract | Atherosclerosis is often associated with chronic vascular inflammation. High-mobility group box 1 protein (HMGB1) plays various roles, not only as a transcriptional regulatory factor in the nucleus, but also as an inflammatory mediator. A previous study suggested that fibrinogen is an important factor associated with atherosclerosis progression. The present study was performed to examine the levels of plasma HMGB1 protein in atherosclerosis patients. We studied 24 patients with peripheral artery disease (PAD) with atherosclerosis, and 10 healthy controls. We found that the concentrations of HMGB1 were increased in the plasma of the patients with atherosclerosis, and there were significant correlations between the plasma HMGB1 and fibrinogen levels. Plasma HMGB1 may play a key role in the pathogenesis of clinical and experimental atherosclerosis. |
| Keywords | HMGB1 fibrinogen atherosclerosis peripheral artery disease |
| Amo Type | Original Article |
| Publication Title | Acta Medica Okayama |
| Published Date | 2014-06 |
| Volume | volume68 |
| Issue | issue3 |
| Publisher | Okayama University Medical School |
| Start Page | 157 |
| End Page | 162 |
| ISSN | 0386-300X |
| NCID | AA00508441 |
| Content Type | Journal Article |
| language | English |
| Copyright Holders | CopyrightⒸ 2014 by Okayama University Medical School |
| File Version | publisher |
| Refereed | True |
| PubMed ID | 24942794 |
| Web of Science KeyUT | 000337655600005 |
| Related Url | http://doi.org/10.18926/AMO/52792 |
| JaLCDOI | 10.18926/AMO/52655 |
|---|---|
| FullText URL | 68_3_151.pdf |
| Author | Akavipat, Phuping| Hungsawanich, Nate| Jansin, Rungruedee| |
| Abstract | In neurosurgery in particular, the recommended placement of electrodes for monitoring depth of anesthesia during surgery sometimes conflicts with the surgical site or patient positioning. Therefore, we proposed this study to evaluate the agreement and correlation of bispectral index values recorded from the usual frontal area and the alternate, post-auricular areas in neurosurgery patients. Thirty-four patients scheduled for neurosurgery under general anesthesia were included. Bispectral index (BIS) sensors were placed at both the frontal and post-auricular areas. The anesthesia given was clinically adjusted according to the frontal (standard) BIS reading. The BIS values and impedance were recorded;Pearsonʼs correlation and Bland-Altman plots were analyzed. The bias ± 2SD for the electrode placement before, during, and post-anesthesia were 0±23.32, 1.5±10.69, and 2.1±13.52, while the limits of agreement were －23.3 to 23.3, －12.2 to 9.2, and －17.7 to 13.5, respectively. The correlation coefficient between frontal- and post-auricular-area electrodes was 0.74 with a p-value ＜0.001.The post-auricular placement of a BIS electrode is a practical alternative to frontal lobe placement. Nevertheless, proper electrode location is important to minimize error. |
| Keywords | Bland and Altman analysis electroencephalogram instrumentation equipment |
| Amo Type | Original Article |
| Publication Title | Acta Medica Okayama |
| Published Date | 2014-06 |
| Volume | volume68 |
| Issue | issue3 |
| Publisher | Okayama University Medical School |
| Start Page | 151 |
| End Page | 155 |
| ISSN | 0386-300X |
| NCID | AA00508441 |
| Content Type | Journal Article |
| language | English |
| Copyright Holders | CopyrightⒸ 2014 by Okayama University Medical School |
| File Version | publisher |
| Refereed | True |
| PubMed ID | 24942793 |
| Web of Science KeyUT | 000337655600004 |
