result 13609 件
| JaLCDOI | 10.18926/AMO/43827 |
|---|---|
| FullText URL | 65_1_27.pdf |
| Author | Togami, Taro| Yamamoto, Yuka| Satoh, Katashi| Kameyama, Reiko| Murota, Makiko| Kimura, Naruhide| Nishiyama, Yoshihiro| |
| Abstract | We performed a retrospective study examining the prevalence and subtypes of pulmonary emphysema (PE) identified by computed tomography (CT) in females. We reviewed the records of 1,687 female subjects who had undergone CT. They were divided into the following 2 age groups:group A (＜50 years) and group B (>_50 years). PE was diagnosed by the presence of low-attenuation areas using visual assessment (grades 0-3) on CT images. Two subtypes of PE were observed:centrilobular emphysema (CLE) and paraseptal emphysema (PSE). PE was divided into the following 3 categories:I (CLE or CLE-predominant);II (CLE and PSE of equal extent);and III (PSE or PSE-predominant). PE was found in 64 of 274 smokers (23.3%) and 54 of 1,413 non-smokers (3.8%). In smoking subjects, when grades 1 and 2 were grouped together as mild PE, the mean age for CT grade 3 (severe PE) was significantly higher than that for mild PE. In group A, category III predominated, whereas category I was more prevalent in group B, in both smoking and non-smoking subjects. A high incidence of PE was found in smoking subjects as compared with non-smoking subjects. PSE predominated in younger subjects, whereas CLE predominated in older subjects. |
| Keywords | cigarette smoking CT pulmonary emphysema females |
| Amo Type | Original Article |
| Publication Title | Acta Medica Okayama |
| Published Date | 2011-02 |
| Volume | volume65 |
| Issue | issue1 |
| Publisher | Okayama University Medical School |
| Start Page | 27 |
| End Page | 32 |
| ISSN | 0386-300X |
| NCID | AA00508441 |
| Content Type | Journal Article |
| language | English |
| Copyright Holders | CopyrightⒸ 2011 by Okayama University Medical School |
| File Version | publisher |
| Refereed | True |
| PubMed ID | 21339793 |
| Web of Science KeyUT | 000287620500004 |
| JaLCDOI | 10.18926/AMO/43826 |
|---|---|
| FullText URL | 65_1_21.pdf |
| Author | Tamura, Hiroko| Suzue, Takeshi| Jitsunari, Fumihiko| Hirao, Tomohiro| |
| Abstract | The aim of this study was to evaluate the carotid arterial intima-media thickness (IMT) and its relation to clinical parameters in Japanese children. Fifty-two healthy children (39 boys and 13 girls), aged 6-14 years, were enrolled in this cross-sectional investigation study. IMT of the common carotid artery was determined using ultrasonography. We also investigated anthropometric parameters, blood pressure (BP), lifestyles and blood examinations. The mean value of IMT was 0.4±0.1mm, which was lower than the normal value (1.0mm) in adults. IMT was positively correlated with age (r＝0.340) and height (r＝0.346) in boys, while it was positively correlated with body mass index (BMI) (r＝0.584) and diastolic BP (DBP) (r＝0.563) in girls. In addition, IMT was associated with sleeping hours and hours of watching television (TV) by using stepwise regression analysis. In conclusion, IMT increased with aging, and it was linked to some clinical parameters of atherosclerosis and lifestyles in children. Therefore, this reference data will be helpful for future assessment of age-related change in Japanese children in clinical practice, and IMT might be a good predictor of atherosclerosis in Japanese children. |
| Keywords | intima-media thickness (IMT) lifestyle Japanese children proportional hazards models atherosclerosis |
| Amo Type | Original Article |
| Publication Title | Acta Medica Okayama |
| Published Date | 2011-02 |
| Volume | volume65 |
| Issue | issue1 |
| Publisher | Okayama University Medical School |
| Start Page | 21 |
| End Page | 25 |
| ISSN | 0386-300X |
| NCID | AA00508441 |
| Content Type | Journal Article |
| language | English |
| Copyright Holders | CopyrightⒸ 2011 by Okayama University Medical School |
| File Version | publisher |
| Refereed | True |
| PubMed ID | 21339792 |
| Web of Science KeyUT | 000287620500003 |
| JaLCDOI | 10.18926/AMO/43825 |
|---|---|
| FullText URL | 65_1_11.pdf |
| Author | Kuwaki, Kenji| Nouso, Kazuhiro| Kobayashi, Yoshiyuki| Nakamura, Shinichiro| Ito, Yoichi M.| Iwadou, Shouta| Hagihara, Hiroaki| Yasunaka, Tetsuya| Toshimori, Junichi| Miyatake, Hirokazu| Miyoshi, Kenji| Onishi, Hideki| Miyake, Yasuhiro| Shoji, Bon| Takaki, Akinobu| Shiraha, Hidenori| Iwasaki, Yoshiaki| Kobashi, Haruhiko| Yamamoto, Kazuhide| |
| Abstract | The purpose of this study was to build a prognostic model of hepatocellular carcinoma (HCC) using time-dependent covariates to re-evaluate the prognosis at any stage of the disease. The subjects were consecutive HCC patients who were treated at our institute between 1995 and 2007. We constructed time-fixed and time-dependent prognostic models with a training group (n＝336) and compared the prognostic abilities between conventional Cancer of the Liver Italian Program (CLIP) scores, Japan Integrated Staging (JIS) scores, an Okuda classification, and our prognostic models in the testing group (n＝227) with the c-index. The time-dependent prognostic model consisted of main tumor size, tumor number, portal vein invasion, distant metastasis, alpha-fetoprotein, des-gamma-carboxy prothrombin (DCP), bilirubin, and albumin and the weighted scores were set for each factor depending on the hazard ratio for the prognosis. The prognostic index was determined by summing the scores. The c-index values for the CLIP scores, JIS scores, Okuda classification, and our time-dependent model were 0.741, 0.727, 0.609, and 0.870, respectively. These results indicate that our time-dependent model can estimate the prognosis of HCC more precisely than traditional time-fixed models and can be used to re-predict the prognosis of HCC. |
| Keywords | hepatocellular carcinoma humans prognosis proportional hazards models time factors |
| Amo Type | Original Article |
| Publication Title | Acta Medica Okayama |
| Published Date | 2011-02 |
| Volume | volume65 |
| Issue | issue1 |
| Publisher | Okayama University Medical School |
| Start Page | 11 |
| End Page | 19 |
| ISSN | 0386-300X |
| NCID | AA00508441 |
| Content Type | Journal Article |
| language | English |
| Copyright Holders | CopyrightⒸ 2011 by Okayama University Medical School |
| File Version | publisher |
| Refereed | True |
| PubMed ID | 21339791 |
| Web of Science KeyUT | 000287620500002 |
| JaLCDOI | 10.18926/AMO/43824 |
|---|---|
| FullText URL | 65_1_1.pdf |
| Author | Han, Xiao-Jian| Tomizawa, Kazuhito| Fujimura, Atsushi| Ohmori, Iori| Nishiki, Tei-ichi| Matsushita, Masayuki| Matsui, Hideki| |
| Abstract | Mitochondria are important cellular organelles in most metabolic processes and have a highly dynamic nature, undergoing frequent fission and fusion. The dynamic balance between fission and fusion plays critical roles in mitochondrial functions. In recent studies, several large GTPases have been identified as key molecular factors in mitochondrial fission and fusion. Moreover, the posttranslational modifications of these large GTPases, including phosphorylation, ubiquitination and SUMOylation, have been shown to be involved in the regulation of mitochondrial dynamics. Neurons are particularly sensitive and vulnerable to any abnormalities in mitochondrial dynamics, due to their large energy demand and long extended processes. Emerging evidences have thus indicated a strong linkage between mitochondria and neurodegenerative diseases, including Alzheimer's disease, Parkinson's disease and Huntington's disease. In this review, we will describe the regulation of mitochondrial dynamics and its role in neurodegenerative diseases. |
| Keywords | mitochondria phosphorylation ubiquitination SUMOylation neurodegeneration |
| Amo Type | Review |
| Publication Title | Acta Medica Okayama |
| Published Date | 2011-02 |
| Volume | volume65 |
| Issue | issue1 |
| Publisher | Okayama University Medical School |
| Start Page | 1 |
| End Page | 10 |
| ISSN | 0386-300X |
| NCID | AA00508441 |
| Content Type | Journal Article |
| language | English |
| Copyright Holders | CopyrightⒸ 2011 by Okayama University Medical School |
| File Version | publisher |
| Refereed | True |
| PubMed ID | 21339790 |
| Web of Science KeyUT | 000287620500001 |
| JaLCDOI | 10.18926/ESR/42457 |
|---|---|
| Title Alternative | 西南日本の熱変成超苦鉄質岩体中のかんらん石と輝石の組成変化に関する覚書 |
| FullText URL | esr_017_001_005.pdf |
| Author | Nozaka, Toshio| |
| Abstract | This short article presents some diagrams showing the compositional variations of primary and metamorphic olivine, orthopyroxene and clinopyroxene in peridotites and serpentinites from thermally metamorphosed ultramafic complexes in SW Japan. In contrast to olivine, which shows a gradual change of chemical composition corresponding with metamorphic grade, orthopyroxene and clinopyroxene show clear differences in composition between primary and metamorphic phases. Compared with primary pyroxenes, even though their compositions could be variable depending on original rock composition, metamorphic orthopyroxene and metamorphic clinopyroxene is clearly deficient in Cr(2)O(3) and CaO, and in Cr(2)O(3) and Al(2)O(3), respectively. These characteristics are useful for the discrimination between the pyroxenes of different origin. |
| Keywords | chemical composition olivine orthopyroxene clinopyroxene metaperidotite |
| Publication Title | Okayama University Earth Science Report |
| Published Date | 2010-12-24 |
| Volume | volume17 |
| Issue | issue1 |
| Start Page | 1 |
| End Page | 5 |
| ISSN | 1340-7414 |
| language | English |
| Copyright Holders | © 2010 by Okayama University Earth Science Reports Editorial Committee All Rights Reserved |
| File Version | publisher |
| NAID | 120002753315 |
| Author | Department of Earth Sciences, Faculty of Science, Okayama University| |
|---|---|
| Published Date | 2010-12-24 |
| Publication Title | Okayama University Earth Science Report |
| Volume | volume17 |
| Issue | issue1 |
| Content Type | Others |
| Author | Department of Earth Sciences, Faculty of Science, Okayama University| |
|---|---|
| Published Date | 2010-12-24 |
| Publication Title | Okayama University Earth Science Report |
| Volume | volume17 |
| Issue | issue1 |
| Content Type | Others |
| JaLCDOI | 10.18926/OER/42354 |
|---|---|
| FullText URL | oer_005_1_055_074.pdf |
| Author | Uematsu, Tadahiro| |
| Publication Title | 岡山大学経済学会雑誌 |
| Published Date | 1973-07-15 |
| Volume | volume5 |
| Issue | issue1 |
| Start Page | 55 |
| End Page | 74 |
| ISSN | 0386-3069 |
| language | English |
| File Version | publisher |
| NAID | 120002737737 |
| JaLCDOI | 10.18926/OER/42350 |
|---|---|
| FullText URL | oer_006_3-4_088_103.pdf |
| Author | Uematsu, Tadahiro| |
| Publication Title | 岡山大学経済学会雑誌 |
| Published Date | 1975-03-15 |
| Volume | volume6 |
| Issue | issue3-4 |
| Start Page | 88 |
| End Page | 103 |
| ISSN | 0386-3069 |
| language | English |
| File Version | publisher |
| NAID | 120002737638 |
| JaLCDOI | 10.18926/OER/42227 |
|---|---|
| FullText URL | oer_012_2_077_089.pdf |
| Author | Maruyama, Masayoshi| |
| Publication Title | 岡山大学経済学会雑誌 |
| Published Date | 1980-09-25 |
| Volume | volume12 |
| Issue | issue2 |
| Start Page | 77 |
| End Page | 89 |
| ISSN | 0386-3069 |
| language | English |
| File Version | publisher |
| NAID | 120002737505 |
| JaLCDOI | 10.18926/OER/42195 |
|---|---|
| Title Alternative | 7 Petitionen aus den südsächsischen zum Rittergut Purschenstein gehörigen Orten in 1830 und 1832 (IV) |
| FullText URL | oer_013_1_237_276.pdf |
| Author | Matsuo, Nobushige| |
| Publication Title | 岡山大学経済学会雑誌 |
| Published Date | 1981-05-31 |
| Volume | volume13 |
| Issue | issue1 |
| Start Page | 237 |
| End Page | 276 |
| ISSN | 0386-3069 |
| language | English |
| File Version | publisher |
| NAID | 120002737544 |
| JaLCDOI | 10.18926/OER/42194 |
|---|---|
| FullText URL | oer_013_1_205_235.pdf |
| Author | Yagi, Kiichiro| |
| Publication Title | 岡山大学経済学会雑誌 |
| Published Date | 1981-05-31 |
| Volume | volume13 |
| Issue | issue1 |
| Start Page | 205 |
| End Page | 235 |
| ISSN | 0386-3069 |
| language | English |
| File Version | publisher |
| NAID | 120002737543 |
| JaLCDOI | 10.18926/OER/42190 |
|---|---|
| FullText URL | oer_013_1_069_088.pdf |
| Author | Maruyama, Masayoshi| |
| Publication Title | 岡山大学経済学会雑誌 |
| Published Date | 1981-05-31 |
| Volume | volume13 |
| Issue | issue1 |
| Start Page | 69 |
| End Page | 88 |
| ISSN | 0386-3069 |
| language | English |
| File Version | publisher |
| NAID | 120002737539 |
| JaLCDOI | 10.18926/OER/42003 |
|---|---|
| FullText URL | oer_019_3-4_369_385.pdf |
| Author | Yamashita, Takahiro| |
| Abstract | The latest census of commerce shows that a drastic change is undergoing in Japanese retail market, especially in convenience goods market. This article is a case study, concernig the changes in the spatial and structural pattern of urban retail system in Japan. Some consideration on the new trends of market competition are also discussed. |
| Publication Title | 岡山大学経済学会雑誌 |
| Published Date | 1988-01-20 |
| Volume | volume19 |
| Issue | issue3-4 |
| Start Page | 369 |
| End Page | 385 |
| ISSN | 0386-3069 |
| language | English |
| File Version | publisher |
| NAID | 120002722991 |
| JaLCDOI | 10.18926/OER/41954 |
|---|---|
| FullText URL | oer_020_3_079_105.pdf |
| Author | Wakisaka, Akira| |
| Publication Title | 岡山大学経済学会雑誌 |
| Published Date | 1988-11-30 |
| Volume | volume20 |
| Issue | issue3 |
| Start Page | 79 |
| End Page | 105 |
| ISSN | 0386-3069 |
| language | English |
| File Version | publisher |
| NAID | 120002722958 |
| JaLCDOI | 10.18926/OER/41943 |
|---|---|
| FullText URL | oer_020_1_163_185.pdf |
| Author | Nishikado, Masami| |
| Publication Title | 岡山大学経済学会雑誌 |
| Published Date | 1988-05-31 |
| Volume | volume20 |
| Issue | issue1 |
| Start Page | 163 |
| End Page | 185 |
| ISSN | 0386-3069 |
| language | English |
| File Version | publisher |
| NAID | 120002722974 |
| JaLCDOI | 10.18926/OER/41942 |
|---|---|
| FullText URL | oer_020_1_145_162.pdf |
| Author | Yamashita, Takahiro| |
| Publication Title | 岡山大学経済学会雑誌 |
| Published Date | 1988-05-31 |
| Volume | volume20 |
| Issue | issue1 |
| Start Page | 145 |
| End Page | 162 |
| ISSN | 0386-3069 |
| language | English |
| File Version | publisher |
| NAID | 120002722973 |
| JaLCDOI | 10.18926/OER/41892 |
|---|---|
| FullText URL | oer_022_3-4_237_253.pdf |
| Author | Ichinose, Atsushi| |
| Publication Title | 岡山大学経済学会雑誌 |
| Published Date | 1991-02-26 |
| Volume | volume22 |
| Issue | issue3-4 |
| Start Page | 237 |
| End Page | 253 |
| ISSN | 0386-3069 |
| language | English |
| File Version | publisher |
| NAID | 120002722889 |
| JaLCDOI | 10.18926/OER/41888 |
|---|---|
| FullText URL | oer_022_3-4_153_176.pdf |
| Author | Nomura, Masami| |
| Publication Title | 岡山大学経済学会雑誌 |
| Published Date | 1991-02-26 |
| Volume | volume22 |
| Issue | issue3-4 |
| Start Page | 153 |
| End Page | 176 |
| ISSN | 0386-3069 |
| language | English |
| File Version | publisher |
| NAID | 120002722893 |
| JaLCDOI | 10.18926/OER/41887 |
|---|---|
| FullText URL | oer_022_3-4_145_151.pdf |
| Author | Fujimoto, Takao| |
| Publication Title | 岡山大学経済学会雑誌 |
| Published Date | 1991-02-26 |
| Volume | volume22 |
| Issue | issue3-4 |
| Start Page | 145 |
| End Page | 151 |
| ISSN | 0386-3069 |
| language | English |
| File Version | publisher |
| NAID | 120002722894 |
