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Author Otani, Yusuke| Yoshikawa, Soichiro| Nagao, Kei| Tanaka, Takehiro| Toyooka, Shinichi| Fujimura, Atsushi|
Keywords Mast cells Connective tissue mast cells Noradrenaline Immunoelectron microscopy SLC22A3
Note The version of record of this article, first published in The Journal of Physiological Sciences, is available online at Publisher’s website: http://dx.doi.org/10.1186/s12576-023-00883-3|
Published Date 2023-10-12
Publication Title The Journal of Physiological Sciences
Volume volume73
Issue issue1
Publisher BMC
Start Page 24
ISSN 1880-6546
NCID AA12129145
Content Type Journal Article
language English
OAI-PMH Set 岡山大学
Copyright Holders © The Author(s) 2023.
File Version publisher
PubMed ID 37828465
DOI 10.1186/s12576-023-00883-3
Web of Science KeyUT 001089236900002
Related Url isVersionOf https://doi.org/10.1186/s12576-023-00883-3
FullText URL fulltext.pdf
Author Tsujino, Noriyoshi| Yamazaki, Daisuke| Nishihara, Yu| Yoshino, Takashi| Higo, Yuji| Tange, Yoshinori|
Published Date 2022-03-30
Publication Title Science Advances
Volume volume8
Issue issue13
Publisher American Association for the Advancement of Science (AAAS)
Start Page eabm1821
ISSN 2375-2548
Content Type Journal Article
language English
OAI-PMH Set 岡山大学
Copyright Holders © 2022 The Authors, some rights reserved
File Version publisher
PubMed ID 35353572
DOI 10.1126/sciadv.abm1821
Web of Science KeyUT 000778886800012
Related Url isVersionOf https://doi.org/10.1126/sciadv.abm1821
FullText URL mjou_066_115_124.pdf
Author Maruyama, Takashi| Seto, Tatsuki|
Abstract In this paper, we generalize the Cantor function to 2-dimensional cubes and construct a cyclic 2-cocycle on the Cantor dust. This cocycle is non-trivial on the pullback of the smooth functions on the 2-dimensional torus with the generalized Cantor function while it vanishes on the Lipschitz functions on the Cantor dust. The cocycle is calculated through the integration of 2-forms on the torus by using a combinatorial Fredholm module.
Keywords Fredholm module Cantor dust cyclic cocycle
Published Date 2024-01
Publication Title Mathematical Journal of Okayama University
Volume volume66
Issue issue1
Publisher Department of Mathematics, Faculty of Science, Okayama University
Start Page 115
End Page 124
ISSN 0030-1566
NCID AA00723502
Content Type Journal Article
language English
Copyright Holders Copyright ©2024 by the Editorial Board of Mathematical Journal of Okayama University
FullText URL fulltext20231031-01.pdf fig20231031-01.pdf
Author Yu, Haibo| Morihara, Ryuta| Ota-Elliott, Ricardo| Bian, Zhihong| Bian, Yuting| Hu, Xinran| Sun, Hongming| Fukui, Yusuke| Abe, Koji| Ishiura, Hiroyuki| Yamashita, Toru|
Keywords Alzheimer's disease (AD) Amyloid-13 oligomers (A13O) Necroptosis Microglia Neurodegeneration
Note © 2023 Elsevier B.V. This manuscript version is made available under the CC-BY-NC-ND 4.0 license https://creativecommons.org/licenses/by-nc-nd/4.0/| This fulltext file will be available in Sep. 2024.|
Published Date 2023-12-15
Publication Title Brain Research
Volume volume1821
Publisher Elsevier BV
Start Page 148565
ISSN 0006-8993
Content Type Journal Article
language English
OAI-PMH Set 岡山大学
Copyright Holders © 2023 Elsevier B.V.
File Version author
PubMed ID 37683777
DOI 10.1016/j.brainres.2023.148565
Web of Science KeyUT 001076471100001
Related Url isVersionOf https://doi.org/10.1016/j.brainres.2023.148565
FullText URL fulltext.pdf
Author Takao, Tomoka| Yamada, Daisuke| Takarada, Takeshi|
Published Date 2022-12-16
Publication Title STAR Protocols
Volume volume3
Issue issue4
Publisher Cell Press
Start Page 101786
ISSN 2666-1667
Content Type Journal Article
language English
OAI-PMH Set 岡山大学
Copyright Holders © 2022 The Author(s).
File Version publisher
PubMed ID 36317170
DOI 10.1016/j.xpro.2022.101786
Web of Science KeyUT 001059369400011
Related Url isVersionOf https://doi.org/10.1016/j.xpro.2022.101786
FullText URL fulltext.pdf
Author TAKAGI, KOSEI| KUMANO, KENJIRO| UMEDA, YUZO| YOSHIDA, RYUICHI| FUJI, TOMOKAZU| YASUI, KAZUYA| YAGI, TAKAHITO| FUJIWARA, TOSHIYOSHI|
Keywords Robot distal pancreatectomy surgical approach splenic artery pancreatic cancer
Published Date 2022-08-23
Publication Title Anticancer Research
Volume volume42
Issue issue9
Publisher Anticancer Research USA Inc.
Start Page 4471
End Page 4476
ISSN 0250-7005
NCID AA10625860
Content Type Journal Article
language English
OAI-PMH Set 岡山大学
Copyright Holders © 2022 International Institute of Anticancer Research (Dr. George J. Delinasios)
File Version publisher
PubMed ID 36039441
DOI 10.21873/anticanres.15947
Web of Science KeyUT 000848585700012
Related Url isVersionOf https://doi.org/10.21873/anticanres.15947
JaLCDOI 10.18926/AMO/65974
FullText URL 77_5_517.pdf
Author Horiguchi, Shigeru| Matsumoto, Kazuyuki| Morimoto, Kosaku| Matsumi, Akihiro| Terasawa, Hiroyuki| Fujii, Yuki| Yamazaki, Tatsuhiro| Tsutsumi, Koichiro| Kato, Hironari|
Abstract We investigated the effect of modified FOLFIRINOX (mFFX) in unresectable pancreatic cancer by retrospectively analyzing the cases of 43 patients who underwent BRCA testing (germline, n=11; somatic, n=26; both germline and somatic, n=6). The association between BRCA mutations and therapeutic effect was clarified. Six patients tested positive for germline pathogenic variants. Familial pancreatic cancer (33% vs. 3%, p=0.006) and peritoneal disseminated lesions (66% vs. 8%, p<0.001) were significantly more common in patients with germline pathogenic variants. The partial response (PR) rate was 100% in the germline BRCA-positive patients, and 27% in the germline BRCA-negative patients (p<0.001). The median progression-free survival (PFS) was not reached for any germline BRCA-positive patients but was 9.0 months for the germline BRCA-negative patients (p=0.042). Patients with stage IV BRCA-associated pancreatic cancer had better overall survival than those with non-BRCA-associated pancreatic cancer, although the difference was nonsignificant (not reached vs. 655 days, p=0.061). Our results demonstrate that a PR and prolonged PFS can be expected in germline BRCA-positive patients after treatment with mFFX. Our findings also suggest that germline BRCA pathogenic variants may be useful as biomarkers for the therapeutic effect of mFFX in patients with pancreatic cancer.
Keywords BRCA FOLFIRINOX pancreatic cancer progression-free survival pathogenic variant
Amo Type Original Article
Publication Title Acta Medica Okayama
Published Date 2023-10
Volume volume77
Issue issue5
Publisher Okayama University Medical School
Start Page 517
End Page 525
ISSN 0386-300X
NCID AA00508441
Content Type Journal Article
language English
Copyright Holders Copyright Ⓒ 2023 by Okayama University Medical School
File Version publisher
Refereed True
PubMed ID 37899263
Web of Science KeyUT 001108661600009
JaLCDOI 10.18926/AMO/65970
FullText URL 77_5_479.pdf
Author Murata, Akiko| Matsumoto, Naomi| Miyaji, Chikara| Takao, Soshi| Yorifuji, Takashi|
Abstract For decades, the notion has persisted in developed countries that exclusive care by the mothers is best for the development of children up to 3 years of age. To examine the veracity of this “myth of the first three years” in Japan, we examined the effects of childcare facility use for children younger than 3 years on their development using the cohorts of the Longitudinal Survey of Newborns in the 21st Century conducted in Japan. Of the 47,015 respondents to the survey, we studied the children of 5,508 mothers with university/professional education to evaluate the relationships between primary early (< 2.5 years) childcare providers during weekday daytime hours and specific development indices for the ages of 2.5, 5.5, and 8 years. At the age of 2.5 and 5.5 years, children attending childcare facilities were judged as having more advanced developmental behaviors by their parents, such as being able to compose a two-word sentence (adjusted odds ratio [aOR]: 0.22) or to express emotions (aOR: 0.81), compared with those cared for by mothers. However, at the age of 8 years, children who attended childcare facilities as infants < 2.5 years showed more aggressive behavior in interrupting people (aOR: 1.20) and causing disturbances in public (aOR: 1.26) than those cared for by mothers (after adjustment for numerous child and parental factors). Although these results are generally consistent with previous studies, issues potentially involved with problem behavior such as quality of childcare require further investigation, as does the case of children of mothers with more modest educational attainment.
Keywords “myth of the first three years” childcare child development problem behavior educational attainment
Amo Type Original Article
Publication Title Acta Medica Okayama
Published Date 2023-10
Volume volume77
Issue issue5
Publisher Okayama University Medical School
Start Page 479
End Page 490
ISSN 0386-300X
NCID AA00508441
Content Type Journal Article
language English
Copyright Holders Copyright Ⓒ 2023 by Okayama University Medical School
File Version publisher
Refereed True
PubMed ID 37899259
Web of Science KeyUT 001108661600005
JaLCDOI 10.18926/AMO/65968
FullText URL 77_5_461.pdf
Author Homma, Daisuke| Minato, Izumi| Imai, Norio| Miyasaka, Dai| Sakai, Yoshinori| Horigome, Yoji| Suzuki, Hayato| Dohmae, Yoichiro| Endo, Naoto|
Abstract This study aimed to determine which muscle the gluteus maximus, gluteus medius, gluteus minimus (Gmin), or tensor fasciae latae (TFL) contributes most to hip abduction strength and to identify effective sites for cross-sectional area (CSA) Gmin and TFL measurement in hip osteoarthritis (OAhip) patients. Twenty-eight patients with OAhip were included. The muscle CSA and volume were determined using magnetic resonance imaging. Peak isometric strength was determined using hand-held dynamometry. Muscle volumes were normalized to the total muscle volume of hip abductors. Multiple regression analysis was performed. The difference between the CSA of Gmin and TFL was calculated, and correlations with volume and muscle strength were determined. Gmin volume was related to abductor muscle strength (p=0.042). The peak CSA of the Gmin correlated with muscle volume and strength. The CSA of the TFL correlated with volume, with no difference between the CSA of the most protruding part of the lesser trochanter and peak CSA. Gmin volume was strongly related to abductor muscle strength. Peak CSA is a useful parameter for assessing the CSA of the Gmin among patients with OAhip. The CSA of the TFL should be measured at the most protruding part of the lesser trochanter.
Keywords gluteus minimus tensor fasciae latae cross-sectional area muscle volume hip osteoarthritis
Amo Type Original Article
Publication Title Acta Medica Okayama
Published Date 2023-10
Volume volume77
Issue issue5
Publisher Okayama University Medical School
Start Page 461
End Page 469
ISSN 0386-300X
NCID AA00508441
Content Type Journal Article
language English
Copyright Holders Copyright Ⓒ 2023 by Okayama University Medical School
File Version publisher
Refereed True
PubMed ID 37899257
Web of Science KeyUT 001108661600003
JaLCDOI 10.18926/AMO/65967
FullText URL 77_5_451.pdf
Author Okita, Atsushi| Tsukuda, Kazunori| Ino, Hideo| Mitsui, Ema| Ikeya, Nanami| Yamamoto, Sumiharu| Yokoyama, Nobuji| Bulin, Aubra|
Abstract Using a Collaborative Action Research model, our research team established a one-month clinical resident training program for first- and second-year clinical residents. We created and implemented an assessment rubric to assess the residents’ progress toward independent practice in surgery, and thereby, to evaluate the program itself. The program included training in three areas: basic techniques and procedures in the operating room, surgical ward management, and academic activities. The rubric measured the residents’ performance according to three achievement levels: Level 1 (demonstration), Level 2 (active help) and Level 3 (passive help). The program and rubric implementation began in June 2019 and continued until March 2020, when the program outcomes and shortcomings were analyzed. Among nineteen clinical residents, a total of nine clinical residents participated in the study. Most participants reached achievement Level 3 for their performance of basic techniques in the operating room. Finally, we discussed ideas for improvement and drafted plans for an improved rubric to complete the action research cycle. Our research team found the rubric to be a useful tool in evaluating the status of the new clinical resident training program.
Keywords resident program rubric assessment general surgery action research
Amo Type Original Article
Publication Title Acta Medica Okayama
Published Date 2023-10
Volume volume77
Issue issue5
Publisher Okayama University Medical School
Start Page 451
End Page 460
ISSN 0386-300X
NCID AA00508441
Content Type Journal Article
language English
Copyright Holders Copyright Ⓒ 2023 by Okayama University Medical School
File Version publisher
Refereed True
PubMed ID 37899256
Web of Science KeyUT 001108661600002
FullText URL fulltext.pdf
Author Khazan, Negar| Kim, Kyu Kwang| Hansen, Jeanne N.| Singh, Niloy A.| Moore, Taylor| Snyder, Cameron W. A.| Pandita, Ravina| Strawderman, Myla| Fujihara, Michiko| Takamura, Yuta| Jian, Ye| Battaglia, Nicholas| Yano, Naohiro| Teramoto, Yuki| Arnold, Leggy A.| Hopson, Russell| Kishor, Keshav| Nayak, Sneha| Ojha, Debasmita| Sharon, Ashoke| Ashton, John M.| Wang, Jian| Milano, Michael T.| Miyamoto, Hiroshi| Linehan, David C.| Gerber, Scott A.| Kawar, Nada| Singh, Ajay P.| Tabdanov, Erdem D.| Dokholyan, Nikolay V.| Kakuta, Hiroki| Jurutka, Peter W.| Schor, Nina F.| Rowswell-Turner, Rachael B.| Singh, Rakesh K.| Moore, Richard G.|
Published Date 2022-04-11
Publication Title Journal of Medicinal Chemistry
Volume volume65
Issue issue8
Publisher American Chemical Society (ACS)
Start Page 6039
End Page 6055
ISSN 0022-2623
NCID AA00702411
Content Type Journal Article
language English
OAI-PMH Set 岡山大学
Copyright Holders © 2022 The Authors.
File Version publisher
PubMed ID 35404047
DOI 10.1021/acs.jmedchem.1c01878
Web of Science KeyUT 000797573100012
Related Url isVersionOf https://doi.org/10.1021/acs.jmedchem.1c01878
FullText URL fulltext.pdf
Author Shuku, Takayuki| Ropponen, Janne| Juntunen, Janne| Suito, Hiroshi|
Published Date 2022-01-18
Publication Title Meteorology and Atmospheric Physics
Volume volume134
Issue issue1
Publisher Springer Science and Business Media LLC
Start Page 18
ISSN 0177-7971
Content Type Journal Article
language English
OAI-PMH Set 岡山大学
Copyright Holders © The Author(s) 2022
File Version publisher
DOI 10.1007/s00703-021-00857-3
Web of Science KeyUT 000743932500001
Related Url isVersionOf https://doi.org/10.1007/s00703-021-00857-3
FullText URL fulltext.pdf
Author Shinoda, Sumio|
Keywords COVID-19 SARS-CoV-2 vaccine Spanish flu influenza
Published Date 2022-01-30
Publication Title Journal of Disaster Research
Volume volume17
Issue issue1
Publisher Fuji Technology Press Ltd.
Start Page 65
End Page 72
ISSN 1883-8030
Content Type Journal Article
language English
OAI-PMH Set 岡山大学
Copyright Holders © Fuji Technology Press Ltd.
File Version publisher
DOI 10.20965/jdr.2022.p0065
Web of Science KeyUT 000748695600008
Related Url isVersionOf https://doi.org/10.20965/jdr.2022.p0065
FullText URL fulltext.pdf
Author Shimooka, So| Akagi, Tetsuya| Dohta, Shujiro| Shinohara, Takashi| Kobayashi, Takumi|
Keywords spiral shaped soft holding actuator extension type flexible pneumatic actuator circumference restraint mechanism analytical model
Published Date 2022-04-20
Publication Title Journal of Robotics and Mechatronics
Volume volume34
Issue issue2
Publisher Fuji Technology Press Ltd.
Start Page 373
End Page 381
ISSN 1883-8049
Content Type Journal Article
language English
OAI-PMH Set 岡山大学
Copyright Holders © Fuji Technology Press Ltd.
File Version publisher
DOI 10.20965/jrm.2022.p0373
Web of Science KeyUT 000795878000037
Related Url isVersionOf https://doi.org/10.20965/jrm.2022.p0373
FullText URL fulltext20231017-01.pdf
Author Ohnuma, Kyosuke| Yamashita, Atsuko| Yasui, Norihisa|
Keywords Crystallography Monellin Protein Stability Recombinant Proteins
Note The version of record of this article, first published in The Protein Journal, is available online at Publisher’s website: http://dx.doi.org/10.1007/s10930-023-10154-0|
Published Date 2023-09-22
Publication Title The Protein Journal
Volume volume42
Issue issue6
Publisher Springer Science and Business Media LLC
Start Page 698
End Page 708
ISSN 1572-3887
Content Type Journal Article
language English
OAI-PMH Set 岡山大学
Copyright Holders © The Author(s) 2023
File Version publisher
PubMed ID 37737932
DOI 10.1007/s10930-023-10154-0
Web of Science KeyUT 001068486400001
Related Url isVersionOf https://doi.org/10.1007/s10930-023-10154-0
FullText URL fulltext20231013-02.pdf
Author Matsumoto, Naomi| Kadowaki, Tomoka| Matsuo, Rumi| Sasaki, Ayako| Miyaji, Chikara| Higuchi, Chigusa| Nakayama, Masanori| Sakurada, Yasue| Hagiya, Hideharu| Takao, Soshi| Otsuka, Fumio| Yorifuji, Takashi|
Keywords SARS-CoV-2 mRNA-1273 antibody reactogenicity adverse reaction
Published Date 2022-12-05
Publication Title Journal of Epidemiology
Volume volume32
Issue issue12
Publisher Japan Epidemiological Association
Start Page 567
End Page 569
ISSN 0917-5040
NCID AA10952696
Content Type Article
language English
OAI-PMH Set 岡山大学
Copyright Holders © 2022 Naomi Matsumoto et al.
File Version publisher
PubMed ID 36031363
DOI 10.2188/jea.je20220210
Web of Science KeyUT 000884682100001
Related Url isVersionOf https://doi.org/10.2188/jea.JE20220210
FullText URL fulltext20231016-01.pdf
Author Hagiya, Hideharu| Otsuka, Fumio|
Keywords Antimicrobial resistance Contact isolation Health care-associated infection Standard precautions
Published Date 2023-09
Publication Title American Journal of Infection Control
Volume volume51
Issue issue9
Publisher Elsevier BV
Start Page 1056
End Page 1062
ISSN 0196-6553
NCID AA10617749
Content Type Journal Article
language English
OAI-PMH Set 岡山大学
Copyright Holders © 2023 The Author(s).
File Version publisher
PubMed ID 36736903
DOI 10.1016/j.ajic.2023.01.018
Web of Science KeyUT 001069295400001
Related Url isVersionOf https://doi.org/10.1016/j.ajic.2023.01.018
FullText URL fulltext20231011-03.pdf
Author Kurihara, Marie| Thiel, Vera| Takahashi, Hirona| Kojima, Keiichi| Ward, David M.| Bryant, Donald A.| Sakai, Makoto| Yoshizawa, Susumu| Sudo, Yuki|
Keywords rhodopsin ion transport retinal isomerization optogenetics
Published Date 2023-02-01
Publication Title Chemical and Pharmaceutical Bulletin
Volume volume71
Issue issue2
Publisher Pharmaceutical Society of Japan
Start Page 154
End Page 164
ISSN 0009-2363
NCID AA00602100
Content Type Journal Article
language English
OAI-PMH Set 岡山大学
Copyright Holders © 2023 The Pharmaceutical Society of Japan
File Version publisher
PubMed ID 36724978
DOI 10.1248/cpb.c22-00774
Web of Science KeyUT 000964953300013
Related Url isVersionOf https://doi.org/10.1248/cpb.c22-00774
FullText URL fulltext.pdf
Author Ikura, Ryohei| Kajimoto, Kota| Park, Junsu| Murayama, Shunsuke| Fujiwara, Yusei| Osaki, Motofumi| Suzuki, Tomohiro| Shirakawa, Hidenori| Kitamura, Yujiro| Takahashi, Hiroaki| Ohashi, Yasumasa| Obata, Seiji| Harada, Akira| Ikemoto, Yuka| Nishina, Yuta| Uetsuji, Yasutomo| Matsuba, Go| Takashima, Yoshinori|
Keywords stress-strain sensor carbon composite movable cross-link supramolecular materials polymericmaterials tough materials upcycling
Published Date 2023-09-11
Publication Title ACS Polymers Au
Volume volume3
Issue issue5
Publisher American Chemical Society
Start Page 394
End Page 405
ISSN 2694-2453
Content Type Journal Article
language English
OAI-PMH Set 岡山大学
Copyright Holders © 2022 The Authors.
File Version publisher
DOI 10.1021/acspolymersau.3c00010
Web of Science KeyUT 001066001800001
Related Url isVersionOf https://doi.org/10.1021/acspolymersau.3c00010
FullText URL fulltext.pdf
Author Saito, Yukihiro| Nose, Naoko| Iida, Toshihiro| Akazawa, Kaoru| Kanno, Takayuki| Fujimoto, Yuki| Sasaki, Takanori| Akehi, Masaru| Higuchi, Takahiro| Akagi, Satoshi| Yoshida, Masashi| Miyoshi, Toru| Ito, Hiroshi| Nakamura, Kazufumi|
Keywords sodium/iodide symporter human induced pluripotent stem cell-derived cardiomyocytes single photon emission computed tomography cell-based therapy in vivo imaging
Published Date 2023-09-07
Publication Title Frontiers in Cardiovascular Medicine
Volume volume10
Publisher Frontiers Media
Start Page 1261330
ISSN 2297-055X
Content Type Journal Article
language English
OAI-PMH Set 岡山大学
Copyright Holders © 2023 Saito, Nose, Iida, Akazawa, Kanno, Fujimoto, Sasaki, Akehi, Higuchi, Akagi, Yoshida, Miyoshi, Ito and Nakamura.
File Version publisher
PubMed ID 37745108
DOI 10.3389/fcvm.2023.1261330
Web of Science KeyUT 001069842100001
Related Url isVersionOf https://doi.org/10.3389/fcvm.2023.1261330