Conditions

close

result 20968 件

FullText URL fulltext.pdf
Author Ishida, Hikaru| Yasui, Norihisa| Yamashita, Atsuko|
Published Date 2024-03-22
Publication Title PLoS ONE
Volume volume19
Issue issue3
Publisher Public Library of Science
Start Page e0300981
ISSN 1932-6203
Content Type Journal Article
language English
OAI-PMH Set 岡山大学
Copyright Holders © 2024 Ishida et al.
File Version publisher
PubMed ID 38517842
DOI 10.1371/journal.pone.0300981
Web of Science KeyUT 001190821200043
Related Url isVersionOf https://doi.org/10.1371/journal.pone.0300981
FullText URL fulltext.pdf
Author Ohsawa, Kumiko| Momose, Shuji| Nishikori, Asami| Nishimura, Midori Filiz| Gion, Yuka| Sawada, Keisuke| Higashi, Morihiro| Tokuhira, Michihide| Tamaru, Jun-Ichi| Sato, Yasuharu|
Keywords classic Hodgkin lymphoma methotrexate immunodeficiency programmed cell death-ligand 1 rheumatoid arthritis
Published Date 2024-03-27
Publication Title Cancers
Volume volume16
Issue issue7
Publisher MDPI
Start Page 1298
ISSN 2072-6694
Content Type Journal Article
language English
OAI-PMH Set 岡山大学
Copyright Holders © 2024 by the authors.
File Version publisher
PubMed ID 38610976
DOI 10.3390/cancers16071298
Web of Science KeyUT 001201068000001
Related Url isVersionOf https://doi.org/10.3390/cancers16071298
JaLCDOI 10.18926/AMO/66916
FullText URL 78_2_135.pdf
Author Higaki, Fumiyo| Morimitsu, Yusuke| Iguchi, Toshihiro| Saito, Hayato| Takaki, Haruhiko| Nakagoshi, Ayako| Wada, Maki| Uka, Mayu| Akagi, Noriaki| Mitsuhashi, Toshiharu| Matsui, Yusuke| Hiraki, Takao|
Abstract This study aimed to evaluate the potential reduction in contrast medium utilization using photon-counting detector computed tomography (PCD-CT). One PCD-CT scan (CT1) and three conventional (non-PCD-CT) CT scans (CT2-CT4) were performed using a multi-energy CT phantom that contained eight rods with different iodine concentrations (0.2, 0.5, 1, 2, 5, 10, 15, and 20 mg/ml). The CT values of the seven groups (CT1 for 40, 50, 60, and 70 keV; and CT2-4) were measured. Noise and contrast-to-noise ratio (CNR) were assessed for the eight rods at various iodine concentrations. CT2 and CT1 (40 keV) respectively required 20 mg/ml and 5 mg/ml of iodine, indicating that a comparable contrast effect could be obtained with approximately one-fourth of the contrast medium amount. The standard deviation values increased at lower energy levels irrespective of the iodine concentration. The CNR exhibited a decreasing trend with lower iodine concentrations, while it remained relatively stable across all iodine levels (40-70 keV). This study demonstrated that virtual monochromatic 40 keV images offer a similar contrast effect with a reduced contrast medium amount when compared to conventional CT systems at 120 kV.
Keywords photon-counting detector CT energy integrating detector CT computed tomography contrast medium amount reduction
Amo Type Original Article
Publication Title Acta Medica Okayama
Published Date 2024-04
Volume volume78
Issue issue2
Publisher Okayama University Medical School
Start Page 135
End Page 142
ISSN 0386-300X
NCID AA00508441
Content Type Journal Article
language English
Copyright Holders Copyright Ⓒ 2024 by Okayama University Medical School
File Version publisher
Refereed True
PubMed ID 38688831
Web of Science KeyUT 001229151800005
JaLCDOI 10.18926/AMO/66915
FullText URL 78_2_123.pdf
Author Saeki, Kyosuke| Fujiwara, Hideaki| Seike, Keisuke| Kuroi, Taiga| Nishimori, Hisakazu| Tanaka, Takehiro| Matsuoka, Ken-ichi| Fujii, Nobuharu| Maeda, Yoshinobu|
Abstract Chronic graft-versus-host disease (GVHD) is a major cause of late death and morbidity following allogeneic hematopoietic cell transplantation (HCT), but its pathogenesis remains unclear. Recently, haplo-identical HCT with post-transplant cyclophosphamide (Haplo-HCT with PTCY) was found to achieve a low incidence rate of acute GVHD and chronic GVHD. However, while the pathogenesis of acute GVHD following Haplo-HCT with PTCY has been well investigated, that of chronic GVHD remains to be elucidated, especially in HLA-matched HCT with PTCY. Based on its safety profile, PTCY is currently applied for the human leucocyte antigen (HLA)-matched HCT setting. Here, we investigated the mechanisms of chronic GVHD following HLA-matched HCT with PTCY using a well-defined mouse chronic GVHD model. PTCY attenuated clinical and pathological chronic GVHD by suppressing effector T-cells and preserving regulatory T-cells compared with a control group. Additionally, we demonstrated that cyclosporine A (CsA) did not show any additional positive effects on attenuation of GVHD in PTCY-treated recipients. These results suggest that monotherapy with PTCY without CsA could be a promising strategy for the prevention of chronic GVHD following HLA-matched HCT.
Keywords GVHD posttransplant cyclophosphamide hematopoietic cell transplantation HLA-identical
Amo Type Original Article
Publication Title Acta Medica Okayama
Published Date 2024-04
Volume volume78
Issue issue2
Publisher Okayama University Medical School
Start Page 123
End Page 134
ISSN 0386-300X
NCID AA00508441
Content Type Journal Article
language English
Copyright Holders Copyright Ⓒ 2024 by Okayama University Medical School
File Version publisher
Refereed True
PubMed ID 38688830
Web of Science KeyUT 001229151800004
JaLCDOI 10.18926/AMO/66912
FullText URL 78_2_095.pdf
Author Itano, Junko| Kiura, Katsuyuki| Maeda, Yoshinobu| Miyahara, Nobuaki|
Abstract The lungs are very complex organs, and the respiratory system performs the dual roles of repairing tissue while protecting against infection from various environmental stimuli. Persistent external irritation disrupts the immune responses of tissues and cells in the respiratory system, ultimately leading to respiratory disease. Neuropeptide Y (NPY) is a 36-amino-acid polypeptide and a neurotransmitter that regulates homeostasis. The NPY receptor is a seven-transmembrane-domain G-protein-coupled receptor with six subtypes (Y1, Y2, Y3, Y4, Y5, and Y6). Of these receptors, Y1, Y2, Y4, and Y5 are functional in humans, and Y1 plays important roles in the immune responses of many organs, including the respiratory system. NPY and the Y1 receptor have critical roles in the pathogenesis of asthma, chronic obstructive pulmonary disease, and idiopathic pulmonary fibrosis. The effects of NPY on the airway immune response and pathogenesis differ among respiratory diseases. This review focuses on the involvement of NPY in the airway immune response and pathogenesis of various respiratory diseases.
Keywords neuropeptide y Y1 receptor airway immune response bronchial epithelial cells respiratory disease
Amo Type Review
Publication Title Acta Medica Okayama
Published Date 2024-04
Volume volume78
Issue issue2
Publisher Okayama University Medical School
Start Page 95
End Page 106
ISSN 0386-300X
NCID AA00508441
Content Type Journal Article
language English
Copyright Holders Copyright Ⓒ 2024 by Okayama University Medical School
File Version publisher
Refereed True
PubMed ID 38688827
Web of Science KeyUT 001229151800001
FullText URL fulltext.pdf
Author Hassan, Ghmkin| Afify, Said M.| Zahra, Maram H.| Nawara, Hend M.| Kumon, Kazuki| Iwasaki, Yoshiaki| Salomon, David S.| Seno, Akimasa| Seno, Masaharu|
Keywords Cancer stem cells Human iPSCs Signal pathway inhibitors Tumor initiation
Note The version of record of this article, first published in Cytotechnology, is available online at Publisher’s website: http://dx.doi.org/10.1007/s10616-023-00575-1|
Published Date 2023-04-01
Publication Title Cytotechnology
Volume volume75
Issue issue3
Publisher Springer Science and Business Media LLC
Start Page 243
End Page 253
ISSN 0920-9069
NCID AA10678299
Content Type Journal Article
language English
OAI-PMH Set 岡山大学
Copyright Holders © The Author(s) 2023
File Version publisher
PubMed ID 37181678
DOI 10.1007/s10616-023-00575-1
Web of Science KeyUT 000961388400001
Related Url isVersionOf https://doi.org/10.1007/s10616-023-00575-1
FullText URL fulltext.pdf
Author Kuwada, Noriaki| Fujii, Yasuhiro| Nakatani, Tatsuyuki| Ousaka, Daiki| Tsuji, Tatsunori| Imai, Yuichi| Kobayashi, Yasuyuki| Oozawa, Susumu| Kasahara, Shingo| Tanemoto, Kazuo|
Keywords Diamond-like carbon Polyurethanes Luminal coating Staphylococcus aureus Prevention of infection
Note The version of record of this article, first published in Journal of Artificial Organs, is available online at Publisher’s website: http://dx.doi.org/10.1007/s10047-023-01403-1|
Published Date 2023-05-25
Publication Title Journal of Artificial Organs
Volume volume27
Issue issue2
Publisher Springer Science and Business Media LLC
Start Page 108
End Page 116
ISSN 1434-7229
NCID AA11283795
Content Type Journal Article
language English
OAI-PMH Set 岡山大学
Copyright Holders © The Author(s) 2023
File Version publisher
PubMed ID 37227545
DOI 10.1007/s10047-023-01403-1
Web of Science KeyUT 000994690300001
Related Url isVersionOf https://doi.org/10.1007/s10047-023-01403-1
FullText URL fulltext.pdf
Author Asada, Noboru| Ando, Jun| Takada, Satoru| Yoshida, Chikashi| Usuki, Kensuke| Shinagawa, Atsushi| Ishizawa, Kenichi| Miyamoto, Toshihiro| Iida, Hiroatsu| Dobashi, Nobuaki| Okubo, Sumiko| Honda, Hideyuki| Soshin, Tomomi| Nishimura, Yasuko| Tsutsui, Atsuko| Mukai, Harumi| Yamamoto, Kazuhito|
Keywords acute myeloid leukemia venetoclax low-dose cytarabine expanded access study tumor lysis syndrome
Published Date 2023-04-04
Publication Title Japanese Journal of Clinical Oncology
Volume volume53
Issue issue7
Publisher Oxford University Press (OUP)
Start Page 595
End Page 603
ISSN 1465-3621
Content Type Journal Article
language English
OAI-PMH Set 岡山大学
Copyright Holders © The Author(s) 2023.
File Version publisher
PubMed ID 37017320
DOI 10.1093/jjco/hyad027
Web of Science KeyUT 000963113000001
Related Url isVersionOf https://doi.org/10.1093/jjco/hyad027
FullText URL fulltext.pdf
Author Nakamichi, Ryo| Saito, Taichi| Shimamura, Yasunori| Hamada, Masanori| Nishida, Keiichiro| Ozaki, Toshifumi|
Keywords Carpal tunnel syndrome Mini-open Endoscopy Patient-oriented evaluation
Note The version of record of this article, first published in BMC Musculoskeletal Disorders, is available online at Publisher’s website: http://dx.doi.org/10.1186/s12891-023-07151-w|
Published Date 2024-04-01
Publication Title BMC Musculoskeletal Disorders
Volume volume25
Issue issue1
Publisher BMC
Start Page 251
ISSN 1471-2474
Content Type Journal Article
language English
OAI-PMH Set 岡山大学
Copyright Holders © The Author(s) 2024.
File Version publisher
PubMed ID 38561698
DOI 10.1186/s12891-023-07151-w
Web of Science KeyUT 001195650000009
Related Url isVersionOf https://doi.org/10.1186/s12891-023-07151-w
FullText URL fulltext.pdf
Author Nakanishi, Fumi| Izumiyama, Shota| Harada, Masayuki| Koshio, Yusuke|
Published Date 2024-04-10
Publication Title The Astrophysical Journal
Volume volume965
Issue issue1
Publisher IOP Publishing Ltd
Start Page 91
ISSN 0004-637X
Content Type Journal Article
language English
OAI-PMH Set 岡山大学
Copyright Holders © 2024. The Author(s).
File Version publisher
DOI 10.3847/1538-4357/ad344e
Web of Science KeyUT 001199593800001
Related Url isVersionOf https://doi.org/10.3847/1538-4357/ad344e
FullText URL fulltext.pdf
Author Taniguchi, Masaharu|
Note The version of record of this article, first published in Mathematische Annalen, is available online at Publisher’s website: http://dx.doi.org/10.1007/s00208-024-02844-6|
Published Date 2024-04-05
Publication Title Mathematische Annalen
Volume volume390
Issue issue3
Publisher Springer Science and Business Media LLC
Start Page 3931
End Page 3967
ISSN 0025-5831
NCID AA00295941
Content Type Journal Article
language English
OAI-PMH Set 岡山大学
Copyright Holders © The Author(s) 2024
File Version publisher
DOI 10.1007/s00208-024-02844-6
Web of Science KeyUT 001197337800002
Related Url isVersionOf https://doi.org/10.1007/s00208-024-02844-6
JaLCDOI 10.18926/interdisciplinary/66892
Title Alternative Interdisciplinary Science Contributing to Sustainable Development of Human Society
FullText URL interdisciplinary_4_1.pdf
Author GOFUKU, Akio|
Abstract With the increase of the complexity of human society because of the globalization and the advancement of each scientific field, innovations by effective collaborations of experts in various fields become necessary to solve problems in human society and to increase the findings of each field. From the backgrounds, the interdisciplinary science b ecomes popular in recent y ears. This article p resents the approach of interdisciplinary science and its importance to the sustainable development of human society. As an example of studies by interdisciplinary science, this article introduces a virtual reality based mirror visual feedback therapy system that the author has been developed in collaboration with medical doctors, professors in engineering field and students of the author’s laboratory in Okayama University.
Keywords Interdisciplinary science Collaboration of medicine and engineering Virtual reality Mirror visual feedback therapy system
Publication Title Interdisciplinary Science
Published Date 2024-03-31
Volume volume4
Start Page 1
End Page 17
ISSN 2436-3227
language Japanese
File Version publisher
FullText URL interdisciplinary_4_contents.pdf
Publication Title Interdisciplinary Science
Published Date 2024-03-31
Volume volume4
ISSN 2436-3227
language Japanese
File Version publisher
FullText URL fulltext.pdf
Author Yoshida, Akari| Ohtsuka, Satomi| Matsumoto, Fumiya| Miyagawa, Tomoyuki| Okino, Rei| Ikeda, Yumeya| Tada, Natsume| Gotoh, Akira| Magari, Masaki| Hatano, Naoya| Morishita, Ryo| Satoh, Ayano| Sunatsuki, Yukinari| Nilsson, Ulf J.| Ishikawa, Teruhiko| Tokumitsu, Hiroshi|
Note The version of record of this article, first published in Scientific Reports, is available online at Publisher’s website: http://dx.doi.org/10.1038/s41598-024-57051-9|
Published Date 2024-03-20
Publication Title Scientific Reports
Volume volume14
Issue issue1
Publisher Nature Portfolio
Start Page 6723
ISSN 2045-2322
Content Type Journal Article
language English
OAI-PMH Set 岡山大学
Copyright Holders © The Author(s) 2024
File Version publisher
PubMed ID 38509168
DOI 10.1038/s41598-024-57051-9
Web of Science KeyUT 001192455600061
Related Url isVersionOf https://doi.org/10.1038/s41598-024-57051-9
FullText URL fulltext.pdf
Author Taniguchi, Rikako| Moriya, Yuto| Dohmae, Naoshi| Suzuki, Takehiro| Nakahara, Kengo| Kubota, Sho| Takasugi, Nobumasa| Uehara, Takashi|
Keywords Nitric oxide S-Nitrosylation Protein arginine methyltransferase 1 (PRMT1) RNA metabolism Dead-box helicase 3X-linxed (DDX3)
Published Date 2024-03
Publication Title Journal of Pharmacological Sciences
Volume volume154
Issue issue3
Publisher Japanese Pharmacological Society
Start Page 209
End Page 217
ISSN 1347-8613
NCID AA11806667
Content Type Journal Article
language English
OAI-PMH Set 岡山大学
Copyright Holders © 2024 The Authors.
File Version publisher
PubMed ID 38395522
DOI 10.1016/j.jphs.2023.12.012
Web of Science KeyUT 001180873100001
Related Url isVersionOf https://doi.org/10.1016/j.jphs.2023.12.012
FullText URL fulltext.pdf
Author Komai, Masato| Noda, Yuka| Ikeda, Atsuya| Kaneshiro, Nanaka| Kamikubo, Yuji| Sakurai, Takashi| Uehara, Takashi| Takasugi, Nobumasa|
Keywords alzheimer's disease apolipoproteins nuclear receptors/RXR transcription sphingosine phosphate astrocytes amyloid β sphingosine kinase 2 low-density lipoprotein receptor-related protein 4
Published Date 2024-03
Publication Title Journal of Lipid Research
Volume volume65
Issue issue3
Publisher Elsevier
Start Page 100510
ISSN 0022-2275
NCID AA00701215
Content Type Journal Article
language English
OAI-PMH Set 岡山大学
Copyright Holders © 2024 THE AUTHORS.
File Version publisher
PubMed ID 38280459
DOI 10.1016/j.jlr.2024.100510
Web of Science KeyUT 001194192200001
Related Url isVersionOf https://doi.org/10.1016/j.jlr.2024.100510
FullText URL fulltext.pdf
Author Kanzaki, Yuki| Matoba, Ryo| Ishihara, Kenji| Morita, Tetsuro| Muraoka, Yuki| Kimura, Shuhei| Koto, Takashi| Kawasaki, Ryo| Baba, Takayuki| Okamoto, Fumiki| Inoue, Makoto| Sakamoto, Taiji| Tsujikawa, Akitaka| Morizane, Yuki|
Published Date 2024-02-08
Publication Title PLoS ONE
Volume volume19
Issue issue2
Publisher Public Library of Science
Start Page e0297347
ISSN 1932-6203
Content Type Journal Article
language English
OAI-PMH Set 岡山大学
Copyright Holders © 2024 Kanzaki et al.
File Version publisher
PubMed ID 38329968
DOI 10.1371/journal.pone.0297347
Web of Science KeyUT 001164302700019
Related Url isVersionOf https://doi.org/10.1371/journal.pone.0297347
FullText URL fulltext.pdf
Author Iwamuro, Masaya| Takenaka, Ryuta| Miyahara, Koji| Okanoue, Shotaro| Yoshioka, Masao| Sakaguchi, Chihiro| Yamamoto, Kumiko| Kawai, Yoshinari| Toyokawa, Tatsuya| Tanaka, Takehiro| Otsuka, Motoyuki|
Keywords Extranodal marginal zone lymphoma of mucosa-associated lymphoid tissue Gastric neoplasms Esophagogastroduodenoscopy t(11;18) translocation, Trisomy 18
Note The version of record of this article, first published in Scientific Reports, is available online at Publisher’s website: http://dx.doi.org/10.1038/s41598-024-55663-9|
Published Date 2024-02-29
Publication Title Scientific Reports
Volume volume14
Issue issue1
Publisher Nature Portfolio
Start Page 4953
ISSN 2045-2322
Content Type Journal Article
language English
OAI-PMH Set 岡山大学
Copyright Holders © The Author(s) 2024
File Version publisher
PubMed ID 38418651
DOI 10.1038/s41598-024-55663-9
Web of Science KeyUT 001178149200009
Related Url isVersionOf https://doi.org/10.1038/s41598-024-55663-9
FullText URL fulltext.pdf
Author Sasaki, Shigenori| Ogawa, Hirohito| Katoh, Hirokazu| Honda, Tomoyuki|
Keywords antiviral antivirals Borna disease virus CRISPR/Cas13b persistent infection
Published Date 2024-03-20
Publication Title International Journal of Molecular Sciences
Volume volume25
Issue issue6
Publisher MDPI
Start Page 3523
ISSN 1661-6596
Content Type Journal Article
language English
OAI-PMH Set 岡山大学
Copyright Holders © 2024 by the authors.
File Version publisher
PubMed ID 38542493
DOI 10.3390/ijms25063523
Web of Science KeyUT 001192979100001
Related Url isVersionOf https://doi.org/10.3390/ijms25063523
FullText URL fulltext.pdf
Author Li, Hongjie| Nakajima, Yoshiki| Nango, Eriko| Owada, Shigeki| Yamada, Daichi| Hashimoto, Kana| Luo, Fangjia| Tanaka, Rie| Akita, Fusamichi| Kato, Koji| Kang, Jungmin| Saitoh, Yasunori| Kishi, Shunpei| Yu, Huaxin| Matsubara, Naoki| Fujii, Hajime| Sugahara, Michihiro| Suzuki, Mamoru| Masuda, Tetsuya| Kimura, Tetsunari| Thao, Tran Nguyen| Yonekura, Shinichiro| Yu, Long-Jiang| Tosha, Takehiko| Tono, Kensuke| Joti, Yasumasa| Hatsui, Takaki| Yabashi, Makina| Kubo, Minoru| Iwata, So| Isobe, Hiroshi| Yamaguchi, Kizashi| Suga, Michihiro| Shen, Jian-Ren|
Note The version of record of this article, first published in Nature, is available online at Publisher’s website: http://dx.doi.org/10.1038/s41586-023-06987-5|
Published Date 2024-01-31
Publication Title Nature
Volume volume626
Issue issue7999
Publisher Springer Science and Business Media LLC
Start Page 670
End Page 677
ISSN 0028-0836
NCID AA00752384
Content Type Journal Article
language English
OAI-PMH Set 岡山大学
Copyright Holders © The Author(s) 2024
File Version publisher
PubMed ID 38297122
DOI 10.1038/s41586-023-06987-5
Web of Science KeyUT 001179152900004
Related Url isVersionOf https://doi.org/10.1038/s41586-023-06987-5