result 20968 件
FullText URL | fulltext.pdf |
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Author | Ishida, Hikaru| Yasui, Norihisa| Yamashita, Atsuko| |
Published Date | 2024-03-22 |
Publication Title | PLoS ONE |
Volume | volume19 |
Issue | issue3 |
Publisher | Public Library of Science |
Start Page | e0300981 |
ISSN | 1932-6203 |
Content Type | Journal Article |
language | English |
OAI-PMH Set | 岡山大学 |
Copyright Holders | © 2024 Ishida et al. |
File Version | publisher |
PubMed ID | 38517842 |
DOI | 10.1371/journal.pone.0300981 |
Web of Science KeyUT | 001190821200043 |
Related Url | isVersionOf https://doi.org/10.1371/journal.pone.0300981 |
FullText URL | fulltext.pdf |
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Author | Ohsawa, Kumiko| Momose, Shuji| Nishikori, Asami| Nishimura, Midori Filiz| Gion, Yuka| Sawada, Keisuke| Higashi, Morihiro| Tokuhira, Michihide| Tamaru, Jun-Ichi| Sato, Yasuharu| |
Keywords | classic Hodgkin lymphoma methotrexate immunodeficiency programmed cell death-ligand 1 rheumatoid arthritis |
Published Date | 2024-03-27 |
Publication Title | Cancers |
Volume | volume16 |
Issue | issue7 |
Publisher | MDPI |
Start Page | 1298 |
ISSN | 2072-6694 |
Content Type | Journal Article |
language | English |
OAI-PMH Set | 岡山大学 |
Copyright Holders | © 2024 by the authors. |
File Version | publisher |
PubMed ID | 38610976 |
DOI | 10.3390/cancers16071298 |
Web of Science KeyUT | 001201068000001 |
Related Url | isVersionOf https://doi.org/10.3390/cancers16071298 |
JaLCDOI | 10.18926/AMO/66916 |
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FullText URL | 78_2_135.pdf |
Author | Higaki, Fumiyo| Morimitsu, Yusuke| Iguchi, Toshihiro| Saito, Hayato| Takaki, Haruhiko| Nakagoshi, Ayako| Wada, Maki| Uka, Mayu| Akagi, Noriaki| Mitsuhashi, Toshiharu| Matsui, Yusuke| Hiraki, Takao| |
Abstract | This study aimed to evaluate the potential reduction in contrast medium utilization using photon-counting detector computed tomography (PCD-CT). One PCD-CT scan (CT1) and three conventional (non-PCD-CT) CT scans (CT2-CT4) were performed using a multi-energy CT phantom that contained eight rods with different iodine concentrations (0.2, 0.5, 1, 2, 5, 10, 15, and 20 mg/ml). The CT values of the seven groups (CT1 for 40, 50, 60, and 70 keV; and CT2-4) were measured. Noise and contrast-to-noise ratio (CNR) were assessed for the eight rods at various iodine concentrations. CT2 and CT1 (40 keV) respectively required 20 mg/ml and 5 mg/ml of iodine, indicating that a comparable contrast effect could be obtained with approximately one-fourth of the contrast medium amount. The standard deviation values increased at lower energy levels irrespective of the iodine concentration. The CNR exhibited a decreasing trend with lower iodine concentrations, while it remained relatively stable across all iodine levels (40-70 keV). This study demonstrated that virtual monochromatic 40 keV images offer a similar contrast effect with a reduced contrast medium amount when compared to conventional CT systems at 120 kV. |
Keywords | photon-counting detector CT energy integrating detector CT computed tomography contrast medium amount reduction |
Amo Type | Original Article |
Publication Title | Acta Medica Okayama |
Published Date | 2024-04 |
Volume | volume78 |
Issue | issue2 |
Publisher | Okayama University Medical School |
Start Page | 135 |
End Page | 142 |
ISSN | 0386-300X |
NCID | AA00508441 |
Content Type | Journal Article |
language | English |
Copyright Holders | Copyright Ⓒ 2024 by Okayama University Medical School |
File Version | publisher |
Refereed | True |
PubMed ID | 38688831 |
Web of Science KeyUT | 001229151800005 |
JaLCDOI | 10.18926/AMO/66915 |
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FullText URL | 78_2_123.pdf |
Author | Saeki, Kyosuke| Fujiwara, Hideaki| Seike, Keisuke| Kuroi, Taiga| Nishimori, Hisakazu| Tanaka, Takehiro| Matsuoka, Ken-ichi| Fujii, Nobuharu| Maeda, Yoshinobu| |
Abstract | Chronic graft-versus-host disease (GVHD) is a major cause of late death and morbidity following allogeneic hematopoietic cell transplantation (HCT), but its pathogenesis remains unclear. Recently, haplo-identical HCT with post-transplant cyclophosphamide (Haplo-HCT with PTCY) was found to achieve a low incidence rate of acute GVHD and chronic GVHD. However, while the pathogenesis of acute GVHD following Haplo-HCT with PTCY has been well investigated, that of chronic GVHD remains to be elucidated, especially in HLA-matched HCT with PTCY. Based on its safety profile, PTCY is currently applied for the human leucocyte antigen (HLA)-matched HCT setting. Here, we investigated the mechanisms of chronic GVHD following HLA-matched HCT with PTCY using a well-defined mouse chronic GVHD model. PTCY attenuated clinical and pathological chronic GVHD by suppressing effector T-cells and preserving regulatory T-cells compared with a control group. Additionally, we demonstrated that cyclosporine A (CsA) did not show any additional positive effects on attenuation of GVHD in PTCY-treated recipients. These results suggest that monotherapy with PTCY without CsA could be a promising strategy for the prevention of chronic GVHD following HLA-matched HCT. |
Keywords | GVHD posttransplant cyclophosphamide hematopoietic cell transplantation HLA-identical |
Amo Type | Original Article |
Publication Title | Acta Medica Okayama |
Published Date | 2024-04 |
Volume | volume78 |
Issue | issue2 |
Publisher | Okayama University Medical School |
Start Page | 123 |
End Page | 134 |
ISSN | 0386-300X |
NCID | AA00508441 |
Content Type | Journal Article |
language | English |
Copyright Holders | Copyright Ⓒ 2024 by Okayama University Medical School |
File Version | publisher |
Refereed | True |
PubMed ID | 38688830 |
Web of Science KeyUT | 001229151800004 |
JaLCDOI | 10.18926/AMO/66912 |
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FullText URL | 78_2_095.pdf |
Author | Itano, Junko| Kiura, Katsuyuki| Maeda, Yoshinobu| Miyahara, Nobuaki| |
Abstract | The lungs are very complex organs, and the respiratory system performs the dual roles of repairing tissue while protecting against infection from various environmental stimuli. Persistent external irritation disrupts the immune responses of tissues and cells in the respiratory system, ultimately leading to respiratory disease. Neuropeptide Y (NPY) is a 36-amino-acid polypeptide and a neurotransmitter that regulates homeostasis. The NPY receptor is a seven-transmembrane-domain G-protein-coupled receptor with six subtypes (Y1, Y2, Y3, Y4, Y5, and Y6). Of these receptors, Y1, Y2, Y4, and Y5 are functional in humans, and Y1 plays important roles in the immune responses of many organs, including the respiratory system. NPY and the Y1 receptor have critical roles in the pathogenesis of asthma, chronic obstructive pulmonary disease, and idiopathic pulmonary fibrosis. The effects of NPY on the airway immune response and pathogenesis differ among respiratory diseases. This review focuses on the involvement of NPY in the airway immune response and pathogenesis of various respiratory diseases. |
Keywords | neuropeptide y Y1 receptor airway immune response bronchial epithelial cells respiratory disease |
Amo Type | Review |
Publication Title | Acta Medica Okayama |
Published Date | 2024-04 |
Volume | volume78 |
Issue | issue2 |
Publisher | Okayama University Medical School |
Start Page | 95 |
End Page | 106 |
ISSN | 0386-300X |
NCID | AA00508441 |
Content Type | Journal Article |
language | English |
Copyright Holders | Copyright Ⓒ 2024 by Okayama University Medical School |
File Version | publisher |
Refereed | True |
PubMed ID | 38688827 |
Web of Science KeyUT | 001229151800001 |
FullText URL | fulltext.pdf |
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Author | Hassan, Ghmkin| Afify, Said M.| Zahra, Maram H.| Nawara, Hend M.| Kumon, Kazuki| Iwasaki, Yoshiaki| Salomon, David S.| Seno, Akimasa| Seno, Masaharu| |
Keywords | Cancer stem cells Human iPSCs Signal pathway inhibitors Tumor initiation |
Note | The version of record of this article, first published in Cytotechnology, is available online at Publisher’s website: http://dx.doi.org/10.1007/s10616-023-00575-1| |
Published Date | 2023-04-01 |
Publication Title | Cytotechnology |
Volume | volume75 |
Issue | issue3 |
Publisher | Springer Science and Business Media LLC |
Start Page | 243 |
End Page | 253 |
ISSN | 0920-9069 |
NCID | AA10678299 |
Content Type | Journal Article |
language | English |
OAI-PMH Set | 岡山大学 |
Copyright Holders | © The Author(s) 2023 |
File Version | publisher |
PubMed ID | 37181678 |
DOI | 10.1007/s10616-023-00575-1 |
Web of Science KeyUT | 000961388400001 |
Related Url | isVersionOf https://doi.org/10.1007/s10616-023-00575-1 |
FullText URL | fulltext.pdf |
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Author | Kuwada, Noriaki| Fujii, Yasuhiro| Nakatani, Tatsuyuki| Ousaka, Daiki| Tsuji, Tatsunori| Imai, Yuichi| Kobayashi, Yasuyuki| Oozawa, Susumu| Kasahara, Shingo| Tanemoto, Kazuo| |
Keywords | Diamond-like carbon Polyurethanes Luminal coating Staphylococcus aureus Prevention of infection |
Note | The version of record of this article, first published in Journal of Artificial Organs, is available online at Publisher’s website: http://dx.doi.org/10.1007/s10047-023-01403-1| |
Published Date | 2023-05-25 |
Publication Title | Journal of Artificial Organs |
Volume | volume27 |
Issue | issue2 |
Publisher | Springer Science and Business Media LLC |
Start Page | 108 |
End Page | 116 |
ISSN | 1434-7229 |
NCID | AA11283795 |
Content Type | Journal Article |
language | English |
OAI-PMH Set | 岡山大学 |
Copyright Holders | © The Author(s) 2023 |
File Version | publisher |
PubMed ID | 37227545 |
DOI | 10.1007/s10047-023-01403-1 |
Web of Science KeyUT | 000994690300001 |
Related Url | isVersionOf https://doi.org/10.1007/s10047-023-01403-1 |
FullText URL | fulltext.pdf |
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Author | Asada, Noboru| Ando, Jun| Takada, Satoru| Yoshida, Chikashi| Usuki, Kensuke| Shinagawa, Atsushi| Ishizawa, Kenichi| Miyamoto, Toshihiro| Iida, Hiroatsu| Dobashi, Nobuaki| Okubo, Sumiko| Honda, Hideyuki| Soshin, Tomomi| Nishimura, Yasuko| Tsutsui, Atsuko| Mukai, Harumi| Yamamoto, Kazuhito| |
Keywords | acute myeloid leukemia venetoclax low-dose cytarabine expanded access study tumor lysis syndrome |
Published Date | 2023-04-04 |
Publication Title | Japanese Journal of Clinical Oncology |
Volume | volume53 |
Issue | issue7 |
Publisher | Oxford University Press (OUP) |
Start Page | 595 |
End Page | 603 |
ISSN | 1465-3621 |
Content Type | Journal Article |
language | English |
OAI-PMH Set | 岡山大学 |
Copyright Holders | © The Author(s) 2023. |
File Version | publisher |
PubMed ID | 37017320 |
DOI | 10.1093/jjco/hyad027 |
Web of Science KeyUT | 000963113000001 |
Related Url | isVersionOf https://doi.org/10.1093/jjco/hyad027 |
FullText URL | fulltext.pdf |
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Author | Nakamichi, Ryo| Saito, Taichi| Shimamura, Yasunori| Hamada, Masanori| Nishida, Keiichiro| Ozaki, Toshifumi| |
Keywords | Carpal tunnel syndrome Mini-open Endoscopy Patient-oriented evaluation |
Note | The version of record of this article, first published in BMC Musculoskeletal Disorders, is available online at Publisher’s website: http://dx.doi.org/10.1186/s12891-023-07151-w| |
Published Date | 2024-04-01 |
Publication Title | BMC Musculoskeletal Disorders |
Volume | volume25 |
Issue | issue1 |
Publisher | BMC |
Start Page | 251 |
ISSN | 1471-2474 |
Content Type | Journal Article |
language | English |
OAI-PMH Set | 岡山大学 |
Copyright Holders | © The Author(s) 2024. |
File Version | publisher |
PubMed ID | 38561698 |
DOI | 10.1186/s12891-023-07151-w |
Web of Science KeyUT | 001195650000009 |
Related Url | isVersionOf https://doi.org/10.1186/s12891-023-07151-w |
FullText URL | fulltext.pdf |
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Author | Nakanishi, Fumi| Izumiyama, Shota| Harada, Masayuki| Koshio, Yusuke| |
Published Date | 2024-04-10 |
Publication Title | The Astrophysical Journal |
Volume | volume965 |
Issue | issue1 |
Publisher | IOP Publishing Ltd |
Start Page | 91 |
ISSN | 0004-637X |
Content Type | Journal Article |
language | English |
OAI-PMH Set | 岡山大学 |
Copyright Holders | © 2024. The Author(s). |
File Version | publisher |
DOI | 10.3847/1538-4357/ad344e |
Web of Science KeyUT | 001199593800001 |
Related Url | isVersionOf https://doi.org/10.3847/1538-4357/ad344e |
FullText URL | fulltext.pdf |
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Author | Taniguchi, Masaharu| |
Note | The version of record of this article, first published in Mathematische Annalen, is available online at Publisher’s website: http://dx.doi.org/10.1007/s00208-024-02844-6| |
Published Date | 2024-04-05 |
Publication Title | Mathematische Annalen |
Volume | volume390 |
Issue | issue3 |
Publisher | Springer Science and Business Media LLC |
Start Page | 3931 |
End Page | 3967 |
ISSN | 0025-5831 |
NCID | AA00295941 |
Content Type | Journal Article |
language | English |
OAI-PMH Set | 岡山大学 |
Copyright Holders | © The Author(s) 2024 |
File Version | publisher |
DOI | 10.1007/s00208-024-02844-6 |
Web of Science KeyUT | 001197337800002 |
Related Url | isVersionOf https://doi.org/10.1007/s00208-024-02844-6 |
JaLCDOI | 10.18926/interdisciplinary/66892 |
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Title Alternative | Interdisciplinary Science Contributing to Sustainable Development of Human Society |
FullText URL | interdisciplinary_4_1.pdf |
Author | GOFUKU, Akio| |
Abstract | With the increase of the complexity of human society because of the globalization and the advancement of each scientific field, innovations by effective collaborations of experts in various fields become necessary to solve problems in human society and to increase the findings of each field. From the backgrounds, the interdisciplinary science b ecomes popular in recent y ears. This article p resents the approach of interdisciplinary science and its importance to the sustainable development of human society. As an example of studies by interdisciplinary science, this article introduces a virtual reality based mirror visual feedback therapy system that the author has been developed in collaboration with medical doctors, professors in engineering field and students of the author’s laboratory in Okayama University. |
Keywords | Interdisciplinary science Collaboration of medicine and engineering Virtual reality Mirror visual feedback therapy system |
Publication Title | Interdisciplinary Science |
Published Date | 2024-03-31 |
Volume | volume4 |
Start Page | 1 |
End Page | 17 |
ISSN | 2436-3227 |
language | Japanese |
File Version | publisher |
FullText URL | interdisciplinary_4_contents.pdf |
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Publication Title | Interdisciplinary Science |
Published Date | 2024-03-31 |
Volume | volume4 |
ISSN | 2436-3227 |
language | Japanese |
File Version | publisher |
FullText URL | fulltext.pdf |
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Author | Yoshida, Akari| Ohtsuka, Satomi| Matsumoto, Fumiya| Miyagawa, Tomoyuki| Okino, Rei| Ikeda, Yumeya| Tada, Natsume| Gotoh, Akira| Magari, Masaki| Hatano, Naoya| Morishita, Ryo| Satoh, Ayano| Sunatsuki, Yukinari| Nilsson, Ulf J.| Ishikawa, Teruhiko| Tokumitsu, Hiroshi| |
Note | The version of record of this article, first published in Scientific Reports, is available online at Publisher’s website: http://dx.doi.org/10.1038/s41598-024-57051-9| |
Published Date | 2024-03-20 |
Publication Title | Scientific Reports |
Volume | volume14 |
Issue | issue1 |
Publisher | Nature Portfolio |
Start Page | 6723 |
ISSN | 2045-2322 |
Content Type | Journal Article |
language | English |
OAI-PMH Set | 岡山大学 |
Copyright Holders | © The Author(s) 2024 |
File Version | publisher |
PubMed ID | 38509168 |
DOI | 10.1038/s41598-024-57051-9 |
Web of Science KeyUT | 001192455600061 |
Related Url | isVersionOf https://doi.org/10.1038/s41598-024-57051-9 |
FullText URL | fulltext.pdf |
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Author | Taniguchi, Rikako| Moriya, Yuto| Dohmae, Naoshi| Suzuki, Takehiro| Nakahara, Kengo| Kubota, Sho| Takasugi, Nobumasa| Uehara, Takashi| |
Keywords | Nitric oxide S-Nitrosylation Protein arginine methyltransferase 1 (PRMT1) RNA metabolism Dead-box helicase 3X-linxed (DDX3) |
Published Date | 2024-03 |
Publication Title | Journal of Pharmacological Sciences |
Volume | volume154 |
Issue | issue3 |
Publisher | Japanese Pharmacological Society |
Start Page | 209 |
End Page | 217 |
ISSN | 1347-8613 |
NCID | AA11806667 |
Content Type | Journal Article |
language | English |
OAI-PMH Set | 岡山大学 |
Copyright Holders | © 2024 The Authors. |
File Version | publisher |
PubMed ID | 38395522 |
DOI | 10.1016/j.jphs.2023.12.012 |
Web of Science KeyUT | 001180873100001 |
Related Url | isVersionOf https://doi.org/10.1016/j.jphs.2023.12.012 |
FullText URL | fulltext.pdf |
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Author | Komai, Masato| Noda, Yuka| Ikeda, Atsuya| Kaneshiro, Nanaka| Kamikubo, Yuji| Sakurai, Takashi| Uehara, Takashi| Takasugi, Nobumasa| |
Keywords | alzheimer's disease apolipoproteins nuclear receptors/RXR transcription sphingosine phosphate astrocytes amyloid β sphingosine kinase 2 low-density lipoprotein receptor-related protein 4 |
Published Date | 2024-03 |
Publication Title | Journal of Lipid Research |
Volume | volume65 |
Issue | issue3 |
Publisher | Elsevier |
Start Page | 100510 |
ISSN | 0022-2275 |
NCID | AA00701215 |
Content Type | Journal Article |
language | English |
OAI-PMH Set | 岡山大学 |
Copyright Holders | © 2024 THE AUTHORS. |
File Version | publisher |
PubMed ID | 38280459 |
DOI | 10.1016/j.jlr.2024.100510 |
Web of Science KeyUT | 001194192200001 |
Related Url | isVersionOf https://doi.org/10.1016/j.jlr.2024.100510 |
FullText URL | fulltext.pdf |
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Author | Kanzaki, Yuki| Matoba, Ryo| Ishihara, Kenji| Morita, Tetsuro| Muraoka, Yuki| Kimura, Shuhei| Koto, Takashi| Kawasaki, Ryo| Baba, Takayuki| Okamoto, Fumiki| Inoue, Makoto| Sakamoto, Taiji| Tsujikawa, Akitaka| Morizane, Yuki| |
Published Date | 2024-02-08 |
Publication Title | PLoS ONE |
Volume | volume19 |
Issue | issue2 |
Publisher | Public Library of Science |
Start Page | e0297347 |
ISSN | 1932-6203 |
Content Type | Journal Article |
language | English |
OAI-PMH Set | 岡山大学 |
Copyright Holders | © 2024 Kanzaki et al. |
File Version | publisher |
PubMed ID | 38329968 |
DOI | 10.1371/journal.pone.0297347 |
Web of Science KeyUT | 001164302700019 |
Related Url | isVersionOf https://doi.org/10.1371/journal.pone.0297347 |
FullText URL | fulltext.pdf |
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Author | Iwamuro, Masaya| Takenaka, Ryuta| Miyahara, Koji| Okanoue, Shotaro| Yoshioka, Masao| Sakaguchi, Chihiro| Yamamoto, Kumiko| Kawai, Yoshinari| Toyokawa, Tatsuya| Tanaka, Takehiro| Otsuka, Motoyuki| |
Keywords | Extranodal marginal zone lymphoma of mucosa-associated lymphoid tissue Gastric neoplasms Esophagogastroduodenoscopy t(11;18) translocation, Trisomy 18 |
Note | The version of record of this article, first published in Scientific Reports, is available online at Publisher’s website: http://dx.doi.org/10.1038/s41598-024-55663-9| |
Published Date | 2024-02-29 |
Publication Title | Scientific Reports |
Volume | volume14 |
Issue | issue1 |
Publisher | Nature Portfolio |
Start Page | 4953 |
ISSN | 2045-2322 |
Content Type | Journal Article |
language | English |
OAI-PMH Set | 岡山大学 |
Copyright Holders | © The Author(s) 2024 |
File Version | publisher |
PubMed ID | 38418651 |
DOI | 10.1038/s41598-024-55663-9 |
Web of Science KeyUT | 001178149200009 |
Related Url | isVersionOf https://doi.org/10.1038/s41598-024-55663-9 |
FullText URL | fulltext.pdf |
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Author | Sasaki, Shigenori| Ogawa, Hirohito| Katoh, Hirokazu| Honda, Tomoyuki| |
Keywords | antiviral antivirals Borna disease virus CRISPR/Cas13b persistent infection |
Published Date | 2024-03-20 |
Publication Title | International Journal of Molecular Sciences |
Volume | volume25 |
Issue | issue6 |
Publisher | MDPI |
Start Page | 3523 |
ISSN | 1661-6596 |
Content Type | Journal Article |
language | English |
OAI-PMH Set | 岡山大学 |
Copyright Holders | © 2024 by the authors. |
File Version | publisher |
PubMed ID | 38542493 |
DOI | 10.3390/ijms25063523 |
Web of Science KeyUT | 001192979100001 |
Related Url | isVersionOf https://doi.org/10.3390/ijms25063523 |
FullText URL | fulltext.pdf |
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Author | Li, Hongjie| Nakajima, Yoshiki| Nango, Eriko| Owada, Shigeki| Yamada, Daichi| Hashimoto, Kana| Luo, Fangjia| Tanaka, Rie| Akita, Fusamichi| Kato, Koji| Kang, Jungmin| Saitoh, Yasunori| Kishi, Shunpei| Yu, Huaxin| Matsubara, Naoki| Fujii, Hajime| Sugahara, Michihiro| Suzuki, Mamoru| Masuda, Tetsuya| Kimura, Tetsunari| Thao, Tran Nguyen| Yonekura, Shinichiro| Yu, Long-Jiang| Tosha, Takehiko| Tono, Kensuke| Joti, Yasumasa| Hatsui, Takaki| Yabashi, Makina| Kubo, Minoru| Iwata, So| Isobe, Hiroshi| Yamaguchi, Kizashi| Suga, Michihiro| Shen, Jian-Ren| |
Note | The version of record of this article, first published in Nature, is available online at Publisher’s website: http://dx.doi.org/10.1038/s41586-023-06987-5| |
Published Date | 2024-01-31 |
Publication Title | Nature |
Volume | volume626 |
Issue | issue7999 |
Publisher | Springer Science and Business Media LLC |
Start Page | 670 |
End Page | 677 |
ISSN | 0028-0836 |
NCID | AA00752384 |
Content Type | Journal Article |
language | English |
OAI-PMH Set | 岡山大学 |
Copyright Holders | © The Author(s) 2024 |
File Version | publisher |
PubMed ID | 38297122 |
DOI | 10.1038/s41586-023-06987-5 |
Web of Science KeyUT | 001179152900004 |
Related Url | isVersionOf https://doi.org/10.1038/s41586-023-06987-5 |