result 24463 件
| JaLCDOI | 10.18926/AMO/49041 |
|---|---|
| FullText URL | 66_6_449.pdf |
| Author | Hanayama, Yoshihisa| Uchida, Haruhito Adam| Nakamura, Yoshio| Makino, Hirofumi| |
| Abstract | Angiotensin receptor blockers (ARBs) are the first-line antihypertensive agents. In clinical practice, it is often difficult to achieve the recommended blood pressure level by ARBs in their ordinal dosages alone. This study examined the practical efficacy of a combination therapy of ARB with thiazide diuretics for lowering morning home blood pressure (MHBP) in comparison to high-dose ARB therapy in patients with morning hypertension administered an ordinal dosage of ARB. This study was performed in a prospective, randomized, open-labeled and blind-endpoint fashion. Patients were considered to have morning hypertension when their self-measured systolic MHBPs were 135mmHg or higher, irrespective of their diastolic MHBP and office blood pressures (OBPs). Forty-eight outpatients with morning hypertension receiving the ordinal dosage of ARB were given either losartan/hydrochlorothiazide (n＝26) or high-dose ARB (n＝22) in place of their previously prescribed ARB. No change in any medication was permitted during this period. Decreases of both systolic and diastolic MHBP after 3 months of treatment were significantly greater in the losartan/hydrochlorothiazide group than in the high-dose ARB group (p＜0.05, respectively). The ratio of adverse events was somewhat high (23.1% in the losartan/hydrochlorothiazide group, 9.1% in the high-dose ARB group, respectively). However, there were no significant differences in any particular adverse event between groups. This study suggested losartan/hydrochlorothiazide might be superior to high-dose ARB for reducing morning home blood pressure. |
| Keywords | losartan hydrochlorothiazide morning blood pressure angiotensin II hyperuricemia |
| Amo Type | Original Article |
| Publication Title | Acta Medica Okayama |
| Published Date | 2012-12 |
| Volume | volume66 |
| Issue | issue6 |
| Publisher | Okayama University Medical School |
| Start Page | 449 |
| End Page | 459 |
| ISSN | 0386-300X |
| NCID | AA00508441 |
| Content Type | Journal Article |
| language | English |
| Copyright Holders | CopyrightⒸ 2012 by Okayama University Medical School |
| File Version | publisher |
| Refereed | True |
| PubMed ID | 23254579 |
| Web of Science KeyUT | 000312966100004 |
| Related Url | http://ousar.lib.okayama-u.ac.jp/metadata/49736 |
| JaLCDOI | 10.18926/AMO/49040 |
|---|---|
| FullText URL | 66_6_443.pdf |
| Author | Ugawa, Toyomu| Sakurama, Kazufumi| Yorifuji, Takashi| Takaoka, Munenori| Fujiwara, Yasuhiro| Kabashima, Narutoshi| Azuma, Daisuke| Hirayama, Takahiro| Tsukahara, Kohei| Morisada, Sunao| Iida, Atsuyoshi| Tada, Keitaro| Shiba, Naoki| Sato, Nobuo| Ichiba, Shingo| Kino, Koichi| Fukushima, Masaki| Ujike, Yoshihito| |
| Abstract | The functioning of an arteriovenous fistula (AVF) used for vascular access during hemodialysis has been assessed mainly by dilution methods. Although these techniques indicate the immediate recirculation rate, the results obtained may not correlate with Kt/V. In contrast, the clearance gap (CL-Gap) method provides the total recirculation rate per dialysis session and correlates well with Kt/V. We assessed the correlation between Kt/V and CL-Gap as well as the change in radial artery (RA) blood flow speed in the fistula before percutaneous transluminal angioplasty (PTA) in 45 patients undergoing continuous hemodialysis. The dialysis dose during the determination of CL-Gap was 1.2 to 1.4 Kt/V. Patients with a 10% elevation or more than a 10% relative increase in CL-Gap underwent PTA (n＝45), and the values obtained for Kt/V and CL-Gap before PTA were compared with those obtained immediately afterward. The mean RA blood flow speed improved significantly (from 52.9 to 97.5cm/sec) after PTA, as did Kt/V (1.07 to 1.30) and CL-Gap (14.1% to －0.2%). A significant correlation between these differences was apparent (r＝－0.436 and p＝0.003). These findings suggest that calculating CL-Gap may be useful for determining when PTA is required and for assessing the effectiveness of PTA, toward obtaining better dialysis. |
| Keywords | hemodialysis recirculation clearance gap vascular access percutaneous transluminal angioplasty |
| Amo Type | Original Article |
| Publication Title | Acta Medica Okayama |
| Published Date | 2012-12 |
| Volume | volume66 |
| Issue | issue6 |
| Publisher | Okayama University Medical School |
| Start Page | 443 |
| End Page | 447 |
| ISSN | 0386-300X |
| NCID | AA00508441 |
| Content Type | Journal Article |
| language | English |
| Copyright Holders | CopyrightⒸ 2012 by Okayama University Medical School |
| File Version | publisher |
| Refereed | True |
| PubMed ID | 23254578 |
| Web of Science KeyUT | 000312966100003 |
| JaLCDOI | 10.18926/AMO/49039 |
|---|---|
| FullText URL | 66_6_435.pdf |
| Author | Fujinaka, Waso| Shimizu, Juichiro| Iribe, Gentaro| Imaoka, Takeshi| Oshima, Yu| Kiyooka, Takahiko| Morita, Kiyoshi| Mohria, Satoshi| |
| Abstract | Although propofol is commonly used for general anesthesia, its direct effects on left ventricular (LV) contractility and energetics remain unknown. Accordingly, we studied the effects of intracoronary propofol on excised cross-circulated canine hearts using the framework of the Emax (a contractility index)-PVA (systolic pressure-volume area, a measure of total mechanical energy)-Vo2 (myocardial oxygen consumption per beat) relationship. We obtained 1) the Vo2-PVA relationship of isovolumic contractions with varied LV volumes at a constant Emax, 2) the Vo2-PVA relationship with varied LV volumes at a constant intracoronary concentration of propofol, and 3) the Vo2-PVA relationship under increased intracoronary concentrations of either propofol or CaCl2 at a constant LV volume to assess the cardiac mechanoenergetic effects of propofol. We found that propofol decreased Emax dose-dependently. The slope of the linear Vo2-PVA relationship (oxygen cost of PVA) remained unchanged by propofol. The PVA-independent Vo2-Emax relationship (oxygen cost of Emax) was the same for propofol and Ca2＋. In conclusion, propofol showed a direct negative inotropic effect on LV. At its clinical concentrations, decreases in contractility by propofol were relatively small. Propofol shows mechanoenergetic effects on the LV that are similar to those of Ca2＋ blockers or ß-antagonists—i.e., it exerts negative inotropic effects without changing the oxygen costs of Emax and PVA. |
| Keywords | anesthesia heart contractility myocardial oxygen consumption |
| Amo Type | Original Article |
| Publication Title | Acta Medica Okayama |
| Published Date | 2012-12 |
| Volume | volume66 |
| Issue | issue6 |
| Publisher | Okayama University Medical School |
| Start Page | 435 |
| End Page | 442 |
| ISSN | 0386-300X |
| NCID | AA00508441 |
| Content Type | Journal Article |
| language | English |
| Copyright Holders | CopyrightⒸ 2012 by Okayama University Medical School |
| File Version | publisher |
| Refereed | True |
| PubMed ID | 23254577 |
| Web of Science KeyUT | 000312966100002 |
| Related Url | http://ousar.lib.okayama-u.ac.jp/metadata/49732 |
| Author | Snyderwine, Elizabeth G.| Davis, Cindy D.| Nouso, Kazuhiro| RoIler, Peter P.| Schut, Herman A.J.| |
|---|---|
| Published Date | 1993-07 |
| Publication Title | Carcinogenesis |
| Volume | volume14 |
| Issue | issue7 |
| Content Type | Journal Article |
| Author | Kanzaki, Hiromitsu| Nouso, Kazuhiro| Miyahara, Koji| Kajikawa, Naoko| Kobayashi, Sayo| Sakakihara, Ichiro| Iwadow, Shota| Uematsu, Shuji| Okamoto, Ryoichi| Shiraga, Kunihiro| Mizuno, Motowo| Araki, Yasuyuki| |
|---|---|
| Published Date | 2009-09-01 |
| Publication Title | Cases Journal |
| Volume | volume2 |
| Content Type | Journal Article |
| Author | Shibasaka, Mineo| Sasano, Sizuka| Utsugi, Sigeko| Katsuhara, Maki| |
|---|---|
| Published Date | 2012-12 |
| Publication Title | Plant Signaling & Behavior |
| Volume | volume7 |
| Issue | issue12 |
| Content Type | Journal Article |
| Author | Takuma, Yoshitaka| Nouso, Kazuhiro| |
|---|---|
| Published Date | 2010-03-28 |
| Publication Title | World Journal of Gastroenterology |
| Volume | volume16 |
| Issue | issue12 |
| Content Type | Journal Article |
| Author | Nakanishi, Yutaka| Shiraha, Hidenori| Nishina, Shin-ichi| Tanaka, Shigetomi| Matsubara, Minoru| Horiguchi, Shigeru| Iwamuro, Masaya| Takaoka, Nobuyuki| Uemura, Masayuki| Kuwaki, Kenji| Hagihara, Hiroaki| Toshimori, Junichi| Ohnishi, Hideki| Takaki, Akinobu| Nakamura, Shinichiro| Kobayashi, Yoshiyuki| Nouso, Kazuhiro| Yagi, Takahito| Yamamoto, Kazuhide| |
|---|---|
| Published Date | 2011-01-04 |
| Publication Title | BMC Cancer |
| Volume | volume11 |
| Content Type | Journal Article |
| Author | Matsuo, Noriyuki| Shiraha, Hidenori| Fujikawa, Tatsuya| Takaoka, Nobuyuki| Ueda, Naoki| Tanaka, Shigetomi| Nishina, Shinichi| Nakanishi, Yutaka| Uemura, Masayuki| Takaki, Akinobu| Nakamura, Shinichiro| Kobayashi, Yoshiyuki| Nouso, Kazuhiro| Yagi, Takahito| Yamamoto, Kazuhide| |
|---|---|
| Published Date | 2009-07-18 |
| Publication Title | BMC Cancer |
| Volume | volume9 |
| Content Type | Journal Article |
| JaLCDOI | 10.18926/OER/49032 |
|---|---|
| Title Alternative | An Evolutionary Analysis of an Asymmetric Tiny Rock-Scissors-Paper Game |
| FullText URL | oer_044_3_093_099.pdf |
| Author | Yokoo, Masanori| |
| Publication Title | 岡山大学経済学会雑誌 |
| Published Date | 2012-12-10 |
| Volume | volume44 |
| Issue | issue3 |
| Start Page | 93 |
| End Page | 99 |
| ISSN | 0386-3069 |
| language | Japanese |
| Copyright Holders | Copyright © 2012 岡山大学経済学会 |
| File Version | publisher |
| NAID | 120005053304 |
| JaLCDOI | 10.18926/OER/49031 |
|---|---|
| Title Alternative | Kaizen based on the Toyota Production System at the Chinese Carmaker FAW Car |
| FullText URL | oer_044_3_073_091.pdf |
| Author | Han, Liang| Shimizu, Koichi| |
| Publication Title | 岡山大学経済学会雑誌 |
| Published Date | 2012-12-10 |
| Volume | volume44 |
| Issue | issue3 |
| Start Page | 73 |
| End Page | 91 |
| ISSN | 0386-3069 |
| language | Japanese |
| Copyright Holders | Copyright © 2012 岡山大学経済学会 |
| File Version | publisher |
| NAID | 120005053303 |
| JaLCDOI | 10.18926/OER/49030 |
|---|---|
| Title Alternative | Relationship Banking in Labor Bank |
| FullText URL | oer_044_3_049_072.pdf |
| Author | Mimura, Satoshi| |
| Abstract | As Labor bank is seemed as business partner of labor union, it contributes each community activities. For example, Labor bank helps retired employee, laborer and inhabitants. In addition, after the amendment of Money Lending Business Act of 2010, labor bank became clearly community based bank by consulting for heavily-indebted people and their education. This paper analyzes the new role of labor bank such as community contribution and enhancing financing service by collecting of the opinion of Financial Services Agency about prolongation of Concept of establishing a Japan Labor Bank |
| Keywords | Relationship Banking Common Bond a Cooperative Financial Institution |
| Publication Title | 岡山大学経済学会雑誌 |
| Published Date | 2012-12-10 |
| Volume | volume44 |
| Issue | issue3 |
| Start Page | 49 |
| End Page | 72 |
| ISSN | 0386-3069 |
| language | Japanese |
| Copyright Holders | Copyright © 2012 岡山大学経済学会 |
| File Version | publisher |
| NAID | 120005053302 |
| JaLCDOI | 10.18926/OER/49029 |
|---|---|
| Title Alternative | Survey of Studies in Hindrance (Resistance) to Organizational Change: Focus on its Factor, Mechanism, Elimination. (the first half ) |
| FullText URL | oer_044_3_023_047.pdf |
| Author | Matsuda, Yoichi| |
| Abstract | Organizational change is important topics in organizational behavior. This paper aims to survey of studies in hindrance (resistance) to organizational change. Especially, we focus on its factor, mechanism, and elimination. And so, suevey previous studies from viewpoint of ①macro organizational theory’s arguments, ②micro organizational theory’s arguments, ③social psychology theory’s arguments, ④consultan’s suggestion. To be continned sequel. (the second half) |
| Publication Title | 岡山大学経済学会雑誌 |
| Published Date | 2012-12-10 |
| Volume | volume44 |
| Issue | issue3 |
| Start Page | 23 |
| End Page | 47 |
| ISSN | 0386-3069 |
| language | Japanese |
| Copyright Holders | Copyright © 2012 岡山大学経済学会 |
| File Version | publisher |
| NAID | 120005053301 |
| JaLCDOI | 10.18926/OER/49028 |
|---|---|
| Title Alternative | Regional Industrial Agglomeration and Home Market Effects: The comparison among three different specifications |
| FullText URL | oer_044_3_001_022.pdf |
| Author | Watanabe, Atsushi| Nakamura, Ryohei| |
| Abstract | The region with a large market tends to increase the number of firms. We can often see the phenomenon of expanding economic disparities between regions. Krugman described this phenomenon using theoretical model and also he defined the concept of home market effect. The home market effect means that the production activity is done over the ratio of market (demand volume) in the region itself. However, by changing the assumption such as Davis (1998), the home market effect does not exist in the theoretical model. Although various empirical studies have been tested, the home market effect has not been necessarily confirmed. In this paper, we analyze the home market effect using the three specifications. Two specifications out of the three specifications are derived from the new economic geography, the rest specification out of the three specifications is derived from international trade. In doing so, it is possible to test the home market effect from various angles, and consider the validity of home market effect. Looking at the overall empirical results, the home market effect is confirmed in a number of manufacturing industries. Also, the home market effect is always confirmed in the six heavy and chemical industries such as chemical industry. |
| Publication Title | 岡山大学経済学会雑誌 |
| Published Date | 2012-12-10 |
| Volume | volume44 |
| Issue | issue3 |
| Start Page | 1 |
| End Page | 22 |
| ISSN | 0386-3069 |
| language | Japanese |
| Copyright Holders | Copyright © 2012 岡山大学経済学会 |
| File Version | publisher |
| NAID | 120005053300 |
| Author | 三宅 三喜男| |
|---|---|
| Published Date | 2012-12-03 |
| Publication Title | 岡山医学会雑誌 |
| Volume | volume124 |
| Issue | issue3 |
| Content Type | Article |
| Author | 石岡 達司| |
|---|---|
| Published Date | 2012-12-03 |
| Publication Title | 岡山医学会雑誌 |
| Volume | volume124 |
| Issue | issue3 |
| Content Type | Article |
| Author | Date, Isao| |
|---|---|
| Published Date | 2012-12-03 |
| Publication Title | 岡山医学会雑誌 |
| Volume | volume124 |
| Issue | issue3 |
| Content Type | Article |
| Author | Matsuoka, Junji| |
|---|---|
| Published Date | 2012-12-03 |
| Publication Title | 岡山医学会雑誌 |
| Volume | volume124 |
| Issue | issue3 |
| Content Type | Article |
| Author | Nishizaki, Kazunori| |
|---|---|
| Published Date | 2012-12-03 |
| Publication Title | 岡山医学会雑誌 |
| Volume | volume124 |
| Issue | issue3 |
| Content Type | Article |
| Author | Doi, Hiroyuki| |
|---|---|
| Published Date | 2012-12-03 |
| Publication Title | 岡山医学会雑誌 |
| Volume | volume124 |
| Issue | issue3 |
| Content Type | Journal Article |
