result 24389 件
| FullText URL | J_Org_Chem_80_6_3111.pdf |
|---|---|
| Author | Takamura, Hiroyoshi| Wada, Hiroko| Ogino, Mao| Kikuchi, Takahiro| Kadota, Isao| Uemura, Daisuke| |
| Note | This is an Accepted Manuscript of an article published by American Chemical Society| This research was supported by a Grant-in Aid for Scientific Research (No. 24710250) from the Japan Society for the Promotion of Science (JSPS).| |
| Published Date | 2015-02-27 |
| Publication Title | The Journal of organic chemistry |
| Volume | volume80 |
| Issue | issue6 |
| Publisher | American Chemical Society |
| Start Page | 3111 |
| End Page | 3123 |
| ISSN | 00223263 |
| NCID | AA00704100 |
| Content Type | Journal Article |
| language | English |
| OAI-PMH Set | 岡山大学 |
| File Version | author |
| PubMed ID | 25723589 |
| DOI | 10.1021/acs.joc.5b00027 |
| Web of Science KeyUT | 000351558400017 |
| Related Url | isVersionOf https://doi.org/10.1021/acs.joc.5b00027 |
| FullText URL | Chemistry_22_6_1984.pdf |
|---|---|
| Author | Takamura, Hiroyoshi| Fujiwara, Takayuki| Kawakubo, Yohei| Kadota, Isao| Uemura, Daisuke| |
| Keywords | macrocycles natural products polyols stereodivergent synthesis structure elucidation |
| Note | This is an article published by WILEY‐VCH| We acknowledge JGC-S Scholarship Foundation, The Naito Foundation, The Sumitomo Foundation, and The Uehara Memorial Foundation for their financial supports. This research was supported by a Grant-in Aid for Scientific Research (No. 24710250) from the Japan Society for the Promotion of Science (JSPS).| |
| Published Date | 2016-02 |
| Publication Title | Chemistry - A European Journal |
| Volume | volume22 |
| Issue | issue6 |
| Publisher | WILEY‐VCH |
| Start Page | 1984 |
| End Page | 1996 |
| ISSN | 0947-6539 |
| NCID | AA11076269 |
| Content Type | Journal Article |
| language | English |
| OAI-PMH Set | 岡山大学 |
| Copyright Holders | https://creativecommons.org/licenses/by-nc-nd/4.0/deed.ja |
| File Version | author |
| PubMed ID | 26742818 |
| DOI | 10.1002/chem.201503881 |
| Web of Science KeyUT | 000368925200016 |
| Related Url | isVersionOf https://doi.org/10.1002/chem.201503881 |
| FullText URL | Chemistry_22_6_1979.pdf |
|---|---|
| Author | Takamura, Hiroyoshi| Fujiwara, Takayuki| Kawakubo, Yohei| Kadota, Isao| Uemura, Daisuke| |
| Keywords | macrocycles natural products polyols stereoselective synthesis structure elucidation |
| Note | This is an article published by Wiley-VCH| We appreciate JGC-S Scholarship Foundation, The Naito Foundation, The Sumitomo Foundation, and The Uehara Memorial Foundation for their financial supports. This research was supported by a Grant-in Aid for Scientific Research (No. 24710250) from the Japan Society for the Promotion of Science (JSPS)| |
| Published Date | 2016-02 |
| Publication Title | Chemistry - A European Journal |
| Volume | volume22 |
| Issue | issue6 |
| Publisher | Wiley-VCH |
| Start Page | 1979 |
| End Page | 1983 |
| ISSN | 0947-6539 |
| NCID | AA11076269 |
| Content Type | Journal Article |
| language | English |
| OAI-PMH Set | 岡山大学 |
| Copyright Holders | https://creativecommons.org/licenses/by-nc-nd/4.0/deed.ja |
| File Version | author |
| PubMed ID | 26661715 |
| DOI | 10.1002/chem.201503880 |
| Web of Science KeyUT | 000368925200015 |
| Related Url | isVersionOf https://doi.org/10.1002/chem.201503880 |
| FullText URL | Org_Lett_18_9_2110.pdf |
|---|---|
| Author | Takamura, Hiroyoshi| Kikuchi, Takahiro| Endo, Noriyuki| Fukuda, Yuji| Kadota, Isao| |
| Note | This is an Accepted Manuscript of an article published by American Chemical Society| This work was supported by Okayama Foundation for Science and Technology and JSPS KAKENHI (24710250).| |
| Published Date | 2016-05-06 |
| Publication Title | Organic Letters |
| Volume | volume18 |
| Issue | issue9 |
| Publisher | American Chemical Society |
| Start Page | 2110 |
| End Page | 2113 |
| ISSN | 15237060 |
| NCID | AA11347843 |
| Content Type | Journal Article |
| language | English |
| OAI-PMH Set | 岡山大学 |
| File Version | author |
| PubMed ID | 27093115 |
| DOI | 10.1021/acs.orglett.6b00737 |
| Web of Science KeyUT | 000375891700042 |
| Related Url | isVersionOf https://doi.org/10.1021/acs.orglett.6b00737 |
| FullText URL | Org_Biomol_Chem_15_26_5549.pdf |
|---|---|
| Author | Takamura, Hiroyoshi| Ohashi, Takumi| Kikuchi, Takahiro| Endo, Noriyuki| Fukuda, Yuji| Kadota, Isao| |
| Note | This is an Accepted Manuscript of an article published by Royal Society of Chemistry| We are grateful to Okayama Foundation for Science and Technology and The Yakumo Foundation for Environmental Science for financial support.| |
| Published Date | 2017-06-13 |
| Publication Title | Organic and Biomolecular Chemistry |
| Volume | volume15 |
| Issue | issue26 |
| Publisher | Royal Society of Chemistry |
| Start Page | 5549 |
| End Page | 5555 |
| ISSN | 14770520 |
| NCID | AA1168650X |
| Content Type | Journal Article |
| language | English |
| OAI-PMH Set | 岡山大学 |
| File Version | author |
| PubMed ID | 28632269 |
| DOI | 10.1039/c7ob01160a |
| Web of Science KeyUT | 000405003900014 |
| Related Url | isVersionOf https://doi.org/10.1039/c7ob01160a |
| FullText URL | Chemistry_23_68_17191.pdf |
|---|---|
| Author | Takamura, Hiroyoshi| Katsube, Tomoya| Okamoto, Kazuki| Kadota, Isao| |
| Keywords | natural products stereoselective synthesis structure elucidation tetrahydrofuran total synthesis |
| Note | This is an article published by Wiley‐VCH| |
| Published Date | 2017-12-06 |
| Publication Title | Chemistry - A European Journal |
| Volume | volume23 |
| Issue | issue68 |
| Publisher | Wiley‐VCH |
| Start Page | 17191 |
| End Page | 17194 |
| ISSN | 09476539 |
| NCID | AA11076269 |
| Content Type | Journal Article |
| language | English |
| OAI-PMH Set | 岡山大学 |
| Copyright Holders | https://creativecommons.org/licenses/by-nc-nd/4.0/deed.ja |
| File Version | author |
| PubMed ID | 29083058 |
| DOI | 10.1002/chem.201703234 |
| Web of Science KeyUT | 000417508800005 |
| Related Url | isVersionOf https://doi.org/10.1002/chem.201703234 |
| FullText URL | PhysRevB_97_104503.pdf |
|---|---|
| Author | He, Tong| Yang, Xiaofan| Terao, Takahiro| Uchiyama, Takaki| Ueno, Teppei| Kobayashi, Kaya| Akimitsu, Jun| Miyazaki, Takafumi| Nishioka, Takumi| Kimura, Koji| Hayashi, Kouichi| Happo, Naohisa| Yamaoka, Hitoshi| Ishii, Hirofumi| Liao, Yen-Fa| Ota, Hiromi| Goto, Hidenori| Kubozono, Yoshihiro| |
| Note | This is an article published by American Physical Society| This study was partly supported by Grants-in-Aid (Grants No. 26105004 and No. 17K05500) from MEXT, by JST ACT-C Grant No. JPMJCR12YW| |
| Published Date | 2018-03-07 |
| Publication Title | Physical Review B |
| Volume | volume97 |
| Issue | issue10 |
| Publisher | American Physical Society |
| Start Page | 104503 |
| ISSN | 01631829 |
| NCID | AA11187113 |
| Content Type | Journal Article |
| language | English |
| OAI-PMH Set | 岡山大学 |
| File Version | publisher |
| DOI | 10.1103/PhysRevB.97.104503 |
| Web of Science KeyUT | 000426776800003 |
| Related Url | isVersionOf https://doi.org/10.1103/PhysRevB.97.104503 |
| FullText URL | PhysRevB_97_094505.pdf |
|---|---|
| Author | Terao, Takahiro| Yang, Xiaofan| Miao, Xiao| Zheng, Lu| Goto, Hidenori| Miyazaki, Takafumi| Yamaoka, Hitoshi| Ishii, Hirofumi| Liao, Yen-Fa| Kubozono, Yoshihiro| |
| Keywords | Superconductors 2-dimensional systems 4-terminal techniques Pressure effects X-ray diffraction |
| Note | This is an article published by American Physical Society| This study was partly supported by Grants-in-Aid (26105004 and 26400361) from MEXT, by JST ACT-C Grant No. JPMJCR12YW, Japan, and by the Program for Promoting the Enhancement of Research Universities.| |
| Published Date | 2018-03-09 |
| Publication Title | Physical Review B |
| Volume | volume97 |
| Issue | issue9 |
| Publisher | American Physical Society |
| Start Page | 094505 |
| ISSN | 01631829 |
| NCID | AA11187113 |
| Content Type | Journal Article |
| language | English |
| OAI-PMH Set | 岡山大学 |
| File Version | publisher |
| DOI | 10.1103/PhysRevB.97.094505 |
| Web of Science KeyUT | 000427010000003 |
| Related Url | isVersionOf https://doi.org/10.1103/PhysRevB.97.094505 |
| FullText URL | Proc_Interspeech_2018_2464.pdf |
|---|---|
| Author | Murakami, Hiroki| Hara, Sunao| Abe, Masanobu| Sato, Masaaki| Minagi, Shogo| |
| Keywords | voice conversion speech intelligibility glossectomy spectral differential neural network |
| Published Date | 2018-09-02 |
| Publication Title | Proceedings of Interspeech 2018 |
| Publisher | International Speech Communication Association |
| Start Page | 2464 |
| End Page | 2468 |
| ISSN | 1990-9772 |
| Content Type | Conference Paper |
| language | English |
| OAI-PMH Set | 岡山大学 |
| File Version | publisher |
| DOI | 10.21437/Interspeech.2018-1239 |
| Related Url | isVersionOf https://doi.org/10.21437/Interspeech.2018-1239 |
| FullText URL | elife_7_30246.pdf |
|---|---|
| Author | Takeda, Tetsuya| Kozai, Toshiya| Yang, Huiran| Ishikuro, Daiki| Seyama, Kaho| Kumagai, Yusuke| Abe, Tadashi| Yamada, Hiroshi| Uchihashi, Takayuki| Ando, Toshio| Takei, Kohji| |
| Keywords | EM HS-AFM amphiphysin biophysics cell biology dynamin human in vitro reconstitution membrane remodeling structural biology |
| Published Date | 2018-01 |
| Publication Title | eLife |
| Volume | volume7 |
| Publisher | eLife Sciences Publications |
| Start Page | e30246 |
| ISSN | 2050-084X |
| Content Type | Journal Article |
| language | English |
| OAI-PMH Set | 岡山大学 |
| File Version | publisher |
| PubMed ID | 29357276 |
| DOI | 10.7554/eLife.30246 |
| Web of Science KeyUT | 000423036500001 |
| Related Url | isVersionOf https://doi.org/10.7554/eLife.30246 |
| FullText URL | Gerodontology_34_1_129.pdf |
|---|---|
| Author | Kobayashi, Naoki| Soga, Yoshihiko| Maekawa, Kyoko| Kanda, Yuko| Kobayashi, Eiko| Inoue, Hisako| Kanao, Ayana| Himuro, Yumiko| Fujiwara, Yumi| |
| Keywords | dementia hospital care mouth risk management |
| Note | This is an Accepted Manuscript of an article published by John Wiley| |
| Published Date | 2017-03 |
| Publication Title | Gerodontology |
| Volume | volume34 |
| Issue | issue1 |
| Publisher | John Wiley |
| Start Page | 129 |
| End Page | 134 |
| ISSN | 0734-0664 |
| NCID | AA10450927 |
| Content Type | Journal Article |
| language | English |
| OAI-PMH Set | 岡山大学 |
| File Version | author |
| PubMed ID | 27207609 |
| DOI | 10.1111/ger.12235 |
| Web of Science KeyUT | 000394951200016 |
| Related Url | isVersionOf https://doi.org/10.1111/ger.12235 |
| Title Alternative | Spatial Analysis and Ecological Approach to Local Society in Ancient Japan |
|---|---|
| FullText URL | 786_63_74_2015.pdf |
| Author | Imazu, Katsunori| |
| Note | 本研究は、「空間解析を通じた日本古代地域社会の研究」（基盤研究（C）研究代表者 岡山大学・社会文化科学研究科・教授･今津勝紀 課題番号15K02833）の成果である。| |
| Published Date | 2015-10 |
| Publication Title | Historical Journal |
| Issue | issue786 |
| Publisher | 歴史科学協議会 |
| Start Page | 63 |
| End Page | 74 |
| ISSN | 0386-8907 |
| NCID | AN00255224 |
| Content Type | Journal Article |
| language | Japanese |
| OAI-PMH Set | 岡山大学 |
| File Version | author |
| NAID | 40020584694 |
| Official Url | http://www.maroon.dti.ne.jp/rekikakyo/magazine/contents/kakonomokuji/786.html| |
| JaLCDOI | 10.18926/ESR/56190 |
|---|---|
| Title Alternative | Interdisciplinary class for high school students on the climate environment around Japan and "seasonal feeling" expressed in the school songs with attention to the asymmetric seasonal march from autumn to the next spring |
| FullText URL | esr_024_1_005_018.pdf |
| Author | Kato, Kuranoshin| Kato, Haruko| Miyake, Shoji| Mori, Taizo| |
| Abstract | This study is a part of the activity to develop an interdisciplinary lesson plan for high school students on the climate environment around Japan and the "seasonal feeling". This time, we focused our attention to the asymmetric seasonal march from autumn to the next spring as proposed by Kato et al. (2013). Comparison of the climate between early winter and early spring was made in the class not only on that around the Japan but also on the relation to the larger-scale systems such as the Siberian air mass, including the brief data analysis. The students also compared the detailed "seasonal feeling" between the two seasons expressed in the school songs and the Japanese classic poems called "Wa-Ka". This paper reports the contents and results of this joint activity at the two high schools. |
| Keywords | Interdisciplinary activity on climate and cultural understanding education Climate environment around Japan Seasonal cycle and "seasonal feeling" Asymmetric seasonal march from autumn to the next spring ESD |
| Publication Title | Okayama University Earth Science Report |
| Published Date | 2017-12-27 |
| Volume | volume24 |
| Issue | issue1 |
| Start Page | 5 |
| End Page | 18 |
| ISSN | 1340-7414 |
| language | Japanese |
| Copyright Holders | © 2017 by Okayama University Earth Science Reports Editorial Committee All Rights Reserved |
| File Version | publisher |
| JaLCDOI | 10.18926/ESR/56189 |
|---|---|
| Title Alternative | Rounded pebble of metamorphosed iron-formations from conglomerate of the Miocene deposits in Yatakayama, Kibi Plateau, Okayama Prefecture |
| FullText URL | esr_024_1_001_004.pdf |
| Author | Suzuki, Shigeyuki| 小網, 晴男| 臼井, まゆみ| |
| Abstract | The Kibi Plateau was a part of the Eurasian Continent and separated by the event of opening of Japan Sea. The rounded pebble which is considered to be continental origin was discovered. The pebble is siliceous and attracts magnets. Prepared thin-sections were observed under microscope. Selected minerals were analyzed by EPMA. The rock is composed of recrystallized quartz, magnetite, riebeckite, stilpnomelane and associated with very tiny minerals with very high relief and interference colors. The assemblage suggests that there is a possibility that the rock is a metamorphic rock of iron-formations and derived from continent. |
| Keywords | Continental origin Miocene conglomerate rounded pebble iron-formations Kibi Plateau |
| Publication Title | Okayama University Earth Science Report |
| Published Date | 2017-12-27 |
| Volume | volume24 |
| Issue | issue1 |
| Start Page | 1 |
| End Page | 4 |
| ISSN | 1340-7414 |
| language | Japanese |
| Copyright Holders | © 2017 by Okayama University Earth Science Reports Editorial Committee All Rights Reserved |
| File Version | publisher |
| JaLCDOI | 10.18926/AMO/56186 |
|---|---|
| FullText URL | 72_4_441.pdf |
| Author | Kida, Daihei| Hashimoto, Hiroya| Saito, Akiko M.| Kito, Yukari| Mori, Kouichi| Terabe, Kenya| Takahashi, Nobunori| Tomita, Yasushi| |
| Abstract | There is no assistive device for extramedullary surgery coordinated with 3D surgical assistive software for the total knee arthroplasty (TKA). We developed a novel extramedullary universal guide coordinated with 3D surgical assistive software and a novel extramedullary patient-specific assistive guide for the placement of femoral components by referring to an area not affected by cartilage or bone spurs, and filed a patent application. In this study, we visualize and reconstruct the total alignment of the lower extremity in TKA using these surgical devices, and validate their precision. A report releasing study results will be submitted in an appropriate journal. |
| Keywords | total knee arthroplasty 3D surgical assistive software tibia femur extramedullary guide |
| Amo Type | Clinical Study Protocol |
| Publication Title | Acta Medica Okayama |
| Published Date | 2018-08 |
| Volume | volume72 |
| Issue | issue4 |
| Publisher | Okayama University Medical School |
| Start Page | 441 |
| End Page | 445 |
| ISSN | 0386-300X |
| NCID | AA00508441 |
| Content Type | Journal Article |
| language | English |
| Copyright Holders | CopyrightⒸ 2018 by Okayama University Medical School |
| File Version | publisher |
| Refereed | True |
| PubMed ID | 30140096 |
| JaLCDOI | 10.18926/AMO/56184 |
|---|---|
| FullText URL | 72_4_431.pdf |
| Author | Sekimizu, Masahiro| Osumi, Tomoo| Fukano, Reiji| Koga, Yuhki| Kada, Akiko| Saito, Akiko M.| Mori, Tetsuya| |
| Abstract | Crizotinib is an inhibitor of multiple tyrosine kinases, including the anaplastic lymphoma kinase (ALK). Responses to crizotinib have also been reported in patients with ALK-positive anaplastic large-cell lymphoma (ALCL) and solid tumors with ALK-mutation, including neuroblastoma. Optimal treatment for patients with recurrent or refractory ALK-positive ALCL and neuroblastoma has not been established. There is a need to develop new drugs for these patients. The objectives of this trial are to evaluate the tolerability and safety of crizotinib in Japanese patients with recurrent/refractory ALK-positive ALCL or neuroblastoma (phase I) and its efficacy in recurrent/refractory ALK-positive ALCL (phase II). |
| Keywords | crizotinib recurrent refractory anaplastic large cell lymphoma neuroblastoma |
| Amo Type | Clinical Study Protocol |
| Publication Title | Acta Medica Okayama |
| Published Date | 2018-08 |
| Volume | volume72 |
| Issue | issue4 |
| Publisher | Okayama University Medical School |
| Start Page | 431 |
| End Page | 436 |
| ISSN | 0386-300X |
| NCID | AA00508441 |
| Content Type | Journal Article |
| language | English |
| Copyright Holders | CopyrightⒸ 2018 by Okayama University Medical School |
| File Version | publisher |
| Refereed | True |
| PubMed ID | 30140094 |
| JaLCDOI | 10.18926/AMO/56181 |
|---|---|
| FullText URL | 72_4_419.pdf |
| Author | Miyake, Susumu| Sugita, Makio| Okazaki, Tomio| Takenaka, Mieko| Kuwabara, Kentarou| Ogawa, Kazunori| |
| Abstract | A 22-year-old Japanese male with trisomy 21 was diagnosed with West syndrome at 4 months old. After the suppression of epileptic spasms using adrenocorticotropic hormone therapy, he had complex partial seizures and bilateral frontal epileptic discharges on EEG. Although the introduction of topiramate (TPM) decreased the seizures during wakefulness, frequent episodes of brief eye-opening appeared during sleep while the patient was taking TPM (400 mg/day). EEG showed fast activity at the times of eye-opening. The episodes of eye-opening during sleep and the fast activities disappeared upon TPM discontinuation. This is the first report of TPM-induced microseizures similar to benzodiazepine-induced microseizures. |
| Keywords | topiramate microseizures paroxysmal fast activity side effects seizure aggravation |
| Amo Type | Case Report |
| Publication Title | Acta Medica Okayama |
| Published Date | 2018-08 |
| Volume | volume72 |
| Issue | issue4 |
| Publisher | Okayama University Medical School |
| Start Page | 419 |
| End Page | 422 |
| ISSN | 0386-300X |
| NCID | AA00508441 |
| Content Type | Journal Article |
| language | English |
| Copyright Holders | CopyrightⒸ 2018 by Okayama University Medical School |
| File Version | publisher |
| Refereed | True |
| PubMed ID | 30140091 |
| JaLCDOI | 10.18926/AMO/56180 |
|---|---|
| FullText URL | 72_4_407.pdf |
| Author | Jung, Chanyul| Jung, Suhun| Chun, Min Ho| Lee, Jong Min| Park, Shinsuk| Kim, Seung-Jong| |
| Abstract | Gait rehabilitation training with robotic exoskeleton is drawing attention as a method for more advanced gait rehabilitation training. However, most of the rehabilitation robots are mainly focused on locomotion training in the sagittal plane. This study introduces a novel gait rehabilitation system with actuated pelvic motion to generate natural gait motion. The rehabilitation robot developed in this study, COWALK, is a lower-body exoskeleton system with 15 degrees of freedom (DoFs). The COWALK can generate multi-DoF pelvic movement along with leg movements. To produce natural gait patterns, the actuation of pelvic movement is essential. In the COWALK, the pelvic movement mechanism is designed to help hemiplegic patients regain gait balance during gait training. To verify the effectiveness of the developed system, the gait patterns with and without pelvic movement were compared to the normal gait on a treadmill. The experimental results show that the active control of pelvic movement combined with the active control of leg movement can make the gait pattern much more natural. |
| Keywords | exoskeleton gait rehabilitation balance control pelvic movement gravity compensation |
| Amo Type | Original Article |
| Publication Title | Acta Medica Okayama |
| Published Date | 2018-08 |
| Volume | volume72 |
| Issue | issue4 |
| Publisher | Okayama University Medical School |
| Start Page | 407 |
| End Page | 417 |
| ISSN | 0386-300X |
| NCID | AA00508441 |
| Content Type | Journal Article |
| language | English |
| Copyright Holders | CopyrightⒸ 2018 by Okayama University Medical School |
| File Version | publisher |
| Refereed | True |
| PubMed ID | 30140090 |
| JaLCDOI | 10.18926/AMO/56178 |
|---|---|
| FullText URL | 72_4_401.pdf |
| Author | Wada, Nozomu| Ikeda, Fusao| Mori, Chizuru| Takaguchi, Koichi| Fujioka, Shin-ichi| Kobashi, Haruhiko| Morimoto, Yoichi| Kariyama, Kazuya| Sakaguchi, Kosaku| Hashimoto, Noriaki| Moriya, Akio| Kawaguchi, Mitsuhiko| Miyatake, Hirokazu| Hagihara, Hiroaki| Kubota, Junichi| Takayama, Hiroki| Takeuchi, Yasuto| Yasunaka, Tetsuya| Takaki, Akinobu| Iwasaki, Yoshiaki| Okada, Hiroyuki| |
| Abstract | Daclatasvir (DCV) + asunaprevir (ASV) combination therapy has become available for patients with hepatitis C virus (HCV) serogroup 1 infection. We studied the efficacy of this therapy by focusing on the factors associated with sustained virological responses (SVR) including resistance-associated variants (RAVs) and mixed infection of different HCV genotypes. We enrolled 951 HCV serogroup 1-positive patients who received this combination therapy at our hospital or affiliated hospitals. The presence of RAVs in non-structural (NS) regions 3 and 5A was analyzed by direct sequencing. HCV genotypes were determined by PCR with genotype-specific primers targeting HCV core and NS5B regions. SVR was achieved in 91.1% of patients. Female sex, age > 70 years, and RAVs were significantly associated with non-SVR (p<0.01 for all). Propensity score-matching results among the patients without RAVs regarding sex, age, and fibrosis revealed that mixed HCV infection determined by HCV NS5B genotyping showed significantly lower SVR rates than 1B-mono infection (p=0.02). Female sex and RAVs were significant factors associated with treatment failure of this combination therapy for patients with HCV serogroup 1 infection. Mixed HCV infection other than 1B-mono infection would be useful for predicting treatment failure. |
| Keywords | mixed genotype daclatasvir asunaprevir HCV serogrouping 1 infection |
| Amo Type | Original Article |
| Publication Title | Acta Medica Okayama |
| Published Date | 2018-08 |
| Volume | volume72 |
| Issue | issue4 |
| Publisher | Okayama University Medical School |
| Start Page | 401 |
| End Page | 406 |
| ISSN | 0386-300X |
| NCID | AA00508441 |
| Content Type | Journal Article |
| language | English |
| Copyright Holders | CopyrightⒸ 2018 by Okayama University Medical School |
| File Version | publisher |
| Refereed | True |
| PubMed ID | 30140089 |
| JaLCDOI | 10.18926/AMO/56177 |
|---|---|
| FullText URL | 72_4_395.pdf |
| Author | Hishii, Shuhei| Miyatake, Nobuyuki| Nishi, Hiroyuki| Katayama, Akihiko| Ujike, Kazuhiro| Koumoto, Kiichi| Hashimoto, Hiroo| |
| Abstract | We explored the relationship between sedentary behavior and the health-related quality of life (HRQOL) in patients on chronic hemodialysis. A total of 60 outpatients, aged 71.1±12.0 years, were enrolled in this cross-sectional study. Sedentary behavior was measured using a tri-accelerometer and HRQOL was evaluated by the Euro-QOL questionnaire (EQ-5D). The relationship between the patients’ sedentary behavior and HRQOL was evaluated by simple and multiple correlation analyses. The relative sedentary behavior (%) for total days was 73.7±12.9% and the EQ-5D scores were 0.688±0.233. Relative sedentary behavior (%) was negatively correlated with EQ-5D scores for total days, hemodialysis days and non-hemodialysis days. The relative light-intensity physical activity (LPA) (%) and relative moderately vigorous-intensity physical activity (MVPA) (%) were correlated with EQ-5D scores. Multiple regression showed that the relative sedentary behavior (%) had a clinical impact on EQ-5D scores after adjusting for confounding factors for total, hemodialysis and non-hemodialysis days. Sedentary behavior is closely linked to HRQOL, and reducing sedentary behavior may be beneficial to improve the HRQOL of patients on chronic hemodialysis. |
| Keywords | physical activity sedentary behavior health-related quality of life HRQOL hemodialysis |
| Amo Type | Original Article |
| Publication Title | Acta Medica Okayama |
| Published Date | 2018-08 |
| Volume | volume72 |
| Issue | issue4 |
| Publisher | Okayama University Medical School |
| Start Page | 395 |
| End Page | 400 |
| ISSN | 0386-300X |
| NCID | AA00508441 |
| Content Type | Journal Article |
| language | English |
| Copyright Holders | CopyrightⒸ 2018 by Okayama University Medical School |
| File Version | publisher |
| Refereed | True |
| PubMed ID | 30140088 |
