検索結果 - OKAYAMA UNIVERSITY SCIENTIFIC ACHIEVEMENT REPOSITORY

Multifunctional Bone Morphogenetic Protein System in Endocrinology

JaLCDOI	10.18926/AMO/49665
FullText URL	67_2_75.pdf
Author	Otsuka, Fumio\|
Abstract	New biological activities of bone morphogenetic proteins (BMPs) in the endocrine system have recently been revealed. The BMP system is composed of approximately 30 ligands and preferential combinations of type I and type II receptors. The BMP system not only induces bone formation but also plays unique tissue-specific roles in various organs. For instance, the ovarian BMP system is a physiological inhibitor of luteinization in growing ovarian follicles. In the ovary, the expression of oocyte-derived BMP-15 is critical for female reproduction. In the pituitary, BMP-4 is a key player for initial development of the anterior pituitary, while it is also functionally involved in some differentiated pituitary tumors, including prolactinoma and Cushingʼs disease. In the adrenal glands, BMP-6 and BMP-4 modulate aldosterone and catecholamine production, respectively, which contributes to a functional interaction between the cortex and medulla. In the present review, recent advances in BMP biology in the field of endocrinology are described and the possibility for clinical application of BMP activity is discussed.
Keywords	bone morphogenetic protein folliculogenesis pituitary adenoma steroidogenesis transforming growth factor
Amo Type	Review
Publication Title	Acta Medica Okayama
Published Date	2013-04
Volume	volume67
Issue	issue2
Publisher	Okayama University Medical School
Start Page	75
End Page	86
ISSN	0386-300X
NCID	AA00508441
Content Type	Journal Article
language	English
Copyright Holders	CopyrightⒸ 2013 by Okayama University Medical School
File Version	publisher
Refereed	True
PubMed ID	23603923
Web of Science KeyUT	000317801700001

Expression of a Constitutively Active Calcineurin Encoded by an Intron-Retaining mRNA in Follicular Keratinocytes

Author	Fujimura, Atsushi\| Michiue, Hiroyuki\| Nishiki, Tei-ichi\| Ohmori, Iori\| Wei, Fanyan\| Matsui, Hideki\| Tomizawa, Kazuhito\|
Published Date	2011-05-14
Publication Title	PLoS ONE
Volume	volume6
Issue	issue3
Content Type	Journal Article

Serum Vaspin Concentrations Are Closely Related to Insulin Resistance, and rs77060950 at SERPINA12 Genetically Defines Distinct Group with Higher Serum Levels in Japanese Population

Author	Teshigawara, Sanae\| Wada, Jun\| Hida, Kazuyuki\| Nakatsuka, Atsuko\| Eguchi, Jun\| Murakami, Kazutoshi\| Kanzaki, Motoko\| Inoue, Kentaro\| Terami, Takahiro\| Katayama, Akihiro\| Iseda, Izumi\| Matsushita, Yuichi\| Miyatake, Nobuyuki\| McDonald, John F.\| Hotta, Kikuko\| Makino, Hirofumi\|
Published Date	2012-07
Publication Title	Journal of Clinical Endocrinology & Metabolism
Volume	volume97
Issue	issue7
Content Type	Journal Article

Acatalasemic mice are mildly susceptible to Acatalasemic mice are mildly susceptible to adriamycin nephropathy and exhibit increased albuminuria and glomerulosclerosis

Author	Takiue, Keiichi\| Sugiyama, Hitoshi\| Inoue, Tatsuyuki\| Morinaga, Hiroshi\| Kikumoto, Yoko\| Kitagawa, Masashi\| Kitamura, Shinji\| Maeshima, Yohei\| Wang, Dahong\| Masuoka, Noriyoshi\| Ogino, Keiki\| Makino, Hirofumi\|
Published Date	2012-05-25
Publication Title	BMC Nephrology
Volume	volume13
Issue	issue14
Content Type	Journal Article

Oral administration of FAK inhibitor TAE226 inhibits the progression of peritoneal dissemination of colorectal cancer

Author	Hao, Hui-fang\| Takaoka, Munenori\| Bao, Xiao-hong\| Wang, Zhi-gang\| Tomono, Yasuko\| Sakurama, Kazufumi\| Ohara, Toshiaki\| Fukazawa, Takuya\| Yamatsuji, Tomoki\| Fujiwara, Toshiyoshi\| Naomoto, Yoshio\|
Published Date	2012-07-13
Publication Title	Biochemical and Biophysical Research Communications
Volume	volume423
Issue	issue4
Content Type	Journal Article

COX/PGE(2) axis critically regulates effects of LPS on eosinophilia-associated cytokine production in nasal polyps

Author	Higaki, T\| Okano, M\| Fujiwara, T\| Makihara, S\| Kariya, S\| Noda, Y\| Haruna, T\| Nishizaki, K\|
Published Date	2012-08
Publication Title	Clinical and Experimental Allergy
Volume	volume42
Issue	issue8
Content Type	Journal Article

Liposomal Delivery of MicroRNA-7-Expressing Plasmid Overcomes Epidermal Growth Factor Receptor Tyrosine Kinase Inhibitor-Resistance in Lung Cancer Cells

Author	Rai, Kammei\| Takigawa, Nagio\| Ito, Sachio\| Kashihara, Hiromi\| Ichihara, Eiki\| Yasuda, Tatsuji\| Shimizu, Kenji\| Tanimoto, Mitsune\| Kiura, Katsuyuki\|
Published Date	2011-09
Publication Title	Molecular Cancer Therapeutics
Volume	volume10
Issue	issue9
Content Type	Journal Article

In vivo imaging of autophagy in a mouse stroke model

FullText URL	Autophagy_6_8_1107-1114.pdf
Author	Tian, FengFeng\| Deguchi, Kentaro\| Yamashita, Toru\| Ohta, Yasuyuki\| Morimoto, Nobutoshi\| Shang, Jingwei\| Zhang, Xuemei\| Liu, Ning\| Ikeda, Yoshio\| Matsuura, Tohru\| Abe, Koji\|
Keywords	autophagy apoptosis GFP-LC3 Tg mice in vivo imaging tMCAO
Published Date	2010-11-16
Publication Title	Autophagy
Volume	volume6
Issue	issue8
Start Page	1107
End Page	1114
ISSN	1554-8627
Content Type	Journal Article
language	English
OAI-PMH Set	岡山大学
File Version	author
PubMed ID	20930570
DOI	10.4161/auto.6.8.13427
Web of Science KeyUT	000284258900010
Official Url	http://doi.org/10.4161/auto.6.8.13427\|
Related Url	http://ousar.lib.okayama-u.ac.jp/metadata/49128

Detection of antibodies against the non-calcium-dependent epitopes of desmoglein 3 in pemphigus vulgaris and their pathogenic significance

Author	Kamiya, K\| Aoyama, Y\| Shirafuji, Y\| Hamada, T\| Morizane, S\| Fujii, K\| Hisata, K\| Iwatsuki, K\|
Published Date	2012-08
Publication Title	British Journal of Dermatology
Volume	volume167
Issue	issue2
Content Type	Journal Article

Therapeutic effect of suicide gene-transferred mesenchymal stem cells in a rat model of glioma

Author	Kosaka, H\| Ichikawa, T\| Kurozumi, K\| Kambara, H\| Inoue, S\| Maruo, T\| Nakamura, K\| Hamada, H\| Date, I\|
Published Date	2012-08
Publication Title	Cancer Gene Therapy
Volume	volume19
Issue	issue8
Content Type	Journal Article

Combining poly-arginine with the hydrophobic counter-anion 4-(1-pyrenyl)-butyric acid for protein transduction in transdermal delivery

Author	Candan, Gerile\| Michiue, Hiroyuki\| Ishikawa, Sanae\| Fujimura, Atsushi\| Hayashi, Keiichiro\| Uneda, Atsuhito\| Mori, Akiko\| Ohmori, Iori\| Nishiki, Tei-ichi\| Matsui, Hideki\| Tomizawa, Kazuhito\|
Published Date	2012-09
Publication Title	Biomaterials
Volume	volume33
Issue	issue27
Content Type	Journal Article

Peroxisome proliferator-activated receptor activity is involved in the osteoblastic differentiation regulated by bone morphogenetic proteins and tumor necrosis factor-α.

FullText URL	MCellularEndocrinology_348_1_224-232.pdf
Author	Takano, Mariko\| Otsuka, Fumio\| Matsumoto, Yoshinori\| Inagaki, Kenichi\| Takeda, Masaya\| Nakamura, Eri\| Tsukamoto, Naoko\| Miyoshi, Tomoko\| Sada, Ken-ei\| Makino, Hirofumi\|
Keywords	Bone morphogenetic protein (BMP) Peroxisome proliferator-activated receptor (PPAR) Osteoblast Tumor necrosis factor-alpha (TNF-alpha)
Published Date	2012-01-02
Publication Title	Molecular and Cellular Endocrinology
Volume	volume348
Issue	issue1
Start Page	224
End Page	232
ISSN	0303-7207
Content Type	Journal Article
language	English
OAI-PMH Set	岡山大学
Copyright Holders	(C) 2011 Elsevier Ireland Ltd. All rights reserved.
File Version	author
DOI	10.1016/j.mce.2011.08.027
Web of Science KeyUT	000297539400025
Related Url	isVesrionOf https://doi.org/10.1016/j.mce.2011.08.027

The hTERT Promoter Enhances the Antitumor Activity of an Oncolytic Adenovirus under a Hypoxic Microenvironment

Author	Hashimoto, Yuuri\| Tazawa, Hiroshi\| Teraishi, Fuminori\| Kojima, Toru\| Watanabe, Yuichi\| Uno, Futoshi\| Yano, Shuya\| Urata, Yasuo\| Kagawa, Shunsuke\| Fujiwara, Toshiyoshi\|
Published Date	2012-06-15
Publication Title	PLoS ONE
Volume	volume7
Issue	issue6
Content Type	Journal Article

Mechanism of resistance to trastuzumab and molecular sensitization via ADCC activation by exogenous expression of HER2-extracellular domain in human cancer cells

Author	Yoshida, Ryosuke\| Tazawa, Hiroshi\| Hashimoto, Yuuri\| Yano, Shuya\| Onishi, Teppei\| Sasaki, Tsuyoshi\| Shirakawa, Yasuhiro\| Kishimoto, Hiroyuki\| Uno, Futoshi\| Nishizaki, Masahiko\| Kagawa, Shunsuke\| Fujiwara, Toshiyoshi\|
Published Date	2012-11
Publication Title	Cancer Immunology, Immunotherapy
Volume	volume61
Issue	issue11
Content Type	Journal Article

Detectability of colorectal neoplasia with fluorine-18-2-fluoro-2-deoxy-D-glucose positron emission tomography and computed tomography (FDG-PET/CT)

Author	Hirakawa, Tomoko\| Kato, Jun\| Okumura, Yoshihiro\| Hori, Keisuke\| Takahashi, Sakuma\| Suzuki, Hideyuki\| Akita, Mitsuhiro\| Higashi, Reiji\| Saito, Shunsuke\| Kaji, Eisuke\| Uraoka, Toshio\| Hiraoka, Sakiko\| Yamamoto, Kazuhide\|
Published Date	2012-02
Publication Title	Journal of Gastroenterology
Volume	volume47
Issue	issue2
Content Type	Journal Article

裏表紙・英文目次

Author	岡山大学大学院社会文化科学研究科\|
Published Date	2013-03-25
Publication Title	岡山大学大学院社会文化科学研究科紀要
Volume	volume35
Content Type	Others

執筆者紹介・奥付

Author	岡山大学大学院社会文化科学研究科\|
Published Date	2013-03-25
Publication Title	岡山大学大学院社会文化科学研究科紀要
Volume	volume35
Content Type	Others

呼びかけ一語文におけるイントネーションの型と意味について

JaLCDOI	10.18926/49533
Title Alternative	The Form and Meaning of the Intonation of Japanese Vocative One-word Sentences
FullText URL	hss_035_147_163.pdf
Author	Li, Zijuan\|
Publication Title	岡山大学大学院社会文化科学研究科紀要
Published Date	2013-03-25
Volume	volume35
Start Page	147
End Page	163
ISSN	1881-1671
language	Japanese
Copyright Holders	Copyright © 2013 岡山大学大学院社会文化科学研究科
File Version	publisher
NAID	120005232471

テヤルの史的変遷

JaLCDOI	10.18926/49532
Title Alternative	The Historical Change of the subsidiary verb“ － teyaru－”
FullText URL	hss_035_131_145.pdf
Author	Toyoda, Keiko\|
Publication Title	岡山大学大学院社会文化科学研究科紀要
Published Date	2013-03-25
Volume	volume35
Start Page	131
End Page	145
ISSN	1881-1671
language	Japanese
Copyright Holders	Copyright © 2013 岡山大学大学院社会文化科学研究科
File Version	publisher
NAID	120005232470

短篇集『ダブリンの市民』の中の作品「恩寵」に見るジェイムズ・ジョイスの教会批判

JaLCDOI	10.18926/49531
Title Alternative	James Joyce and his Criticism of the Church in Grace, a story in Dubliners
FullText URL	hss_035_111_129.pdf
Author	Kaneda, Noriko\|
Publication Title	岡山大学大学院社会文化科学研究科紀要
Published Date	2013-03-25
Volume	volume35
Start Page	111
End Page	129
ISSN	1881-1671
language	Japanese
Copyright Holders	Copyright © 2013 岡山大学大学院社会文化科学研究科
File Version	publisher
NAID	120005232469

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