result 1235 件
| FullText URL | fulltext.pdf |
|---|---|
| Author | Matsuda, Tatsuo| Umeda, Yuzo| Matsuda, Tadakazu| Endo, Yoshikatsu| Sato, Daisuke| Kojima, Toru| Sui, Kenta| Inagaki, Masaru| Ota, Tetsuya| Hioki, Masayoshi| Oishi, Masahiro| Kimura, Masashi| Murata, Toshihiro| Ishido, Nobuhiro| Yagi, Takahito| Fujiwara, Toshiyoshi| |
| Keywords | Intrahepatic cholangiocarcinoma Postoperative complication Prognostic nutritional index |
| Published Date | 2021-06-16 |
| Publication Title | BMC Cancer |
| Volume | volume21 |
| Issue | issue1 |
| Publisher | BMC |
| Start Page | 708 |
| ISSN | 1471-2407 |
| Content Type | Journal Article |
| language | English |
| OAI-PMH Set | 岡山大学 |
| Copyright Holders | © The Author(s). 2021 |
| File Version | publisher |
| PubMed ID | 34130648 |
| DOI | 10.1186/s12885-021-08424-0 |
| Web of Science KeyUT | 000664089600001 |
| Related Url | isVersionOf https://doi.org/10.1186/s12885-021-08424-0 |
| FullText URL | fulltext.pdf |
|---|---|
| Author | Toyama, Naoki| Ekuni, Daisuke| Matsui, Daisuke| Koyama, Teruhide| Nakatochi, Masahiro| Momozawa, Yukihide| Kubo, Michiaki| Morita, Manabu| |
| Keywords | periodontitis microbiota single-nucleotide polymorphisms |
| Published Date | 2021-06-14 |
| Publication Title | International Journal of Environmental Research and Public Health |
| Volume | volume18 |
| Issue | issue12 |
| Publisher | MDPI |
| Start Page | 6430 |
| ISSN | 1660-4601 |
| Content Type | Journal Article |
| language | English |
| OAI-PMH Set | 岡山大学 |
| Copyright Holders | © 2021 by the authors. |
| File Version | publisher |
| PubMed ID | 34198553 |
| DOI | 10.3390/ijerph18126430 |
| Web of Science KeyUT | 000666031300001 |
| Related Url | isVersionOf https://doi.org/10.3390/ijerph18126430 |
| FullText URL | fulltext.pdf |
|---|---|
| Author | Yoshida, Shoko| Shimo, Tsuyoshi| Takabatake, Kiyofumi| Murase, Yurika| Obata, Kyoichi| Okui, Tatsuo| Kunisada, Yuki| Ibaragi, Soichiro| Nagatsuka, Hitoshi| Sasaki, Akira| |
| Keywords | neurokinin B receptor gingival squamous cell carcinoma osteoclast |
| Published Date | 2021-06-07 |
| Publication Title | Diagnostics |
| Volume | volume11 |
| Issue | issue6 |
| Publisher | MDPI |
| Start Page | 1044 |
| ISSN | 2075-4418 |
| Content Type | Journal Article |
| language | English |
| OAI-PMH Set | 岡山大学 |
| Copyright Holders | © 2021 by the authors. |
| File Version | publisher |
| PubMed ID | 34200131 |
| DOI | 10.3390/diagnostics11061044 |
| Web of Science KeyUT | 000667854200001 |
| Related Url | isVersionOf https://doi.org/10.3390/diagnostics11061044 |
| FullText URL | fulltext.pdf |
|---|---|
| Author | Kobayashi, Katsuhiro| Shibata, Takashi| Tsuchiya, Hiroki| Akiyama, Tomoyuki| |
| Keywords | epilepsy child scalp EEG false ripple high-frequency oscillation (HFO) fast oscillation (FO) |
| Published Date | 2021-06-15 |
| Publication Title | Frontiers In Human Neuroscience |
| Volume | volume15 |
| Publisher | Frontiers Media SA |
| Start Page | 696882 |
| ISSN | 1662-5161 |
| Content Type | Journal Article |
| language | English |
| OAI-PMH Set | 岡山大学 |
| Copyright Holders | © 2021 Kobayashi, Shibata, Tsuchiya and Akiyama. |
| File Version | publisher |
| PubMed ID | 34211382 |
| DOI | 10.3389/fnhum.2021.696882 |
| Web of Science KeyUT | 000667490200001 |
| Related Url | isVersionOf https://doi.org/10.3389/fnhum.2021.696882 |
| FullText URL | fulltext.pdf |
|---|---|
| Author | Sukegawa, Shintaro| Yoshii, Kazumasa| Hara, Takeshi| Matsuyama, Tamamo| Yamashita, Katsusuke| Nakano, Keisuke| Takabatake, Kiyofumi| Kawai, Hotaka| Nagatsuka, Hitoshi| Furuki, Yoshihiko| |
| Keywords | multi-task learning deep learning artificial intelligence dental implant classification |
| Published Date | 2021-05-30 |
| Publication Title | Biomolecules |
| Volume | volume11 |
| Issue | issue6 |
| Publisher | MDPI |
| Start Page | 815 |
| ISSN | 2218-273X |
| Content Type | Journal Article |
| language | English |
| OAI-PMH Set | 岡山大学 |
| Copyright Holders | © 2021 by the authors. |
| File Version | publisher |
| PubMed ID | 34070916 |
| DOI | 10.3390/biom11060815 |
| NAID | 120007098536 |
| Web of Science KeyUT | 000665406100001 |
| Related Url | isVersionOf https://doi.org/10.3390/biom11060815 |
| FullText URL | fulltext20210706-2.pdf |
|---|---|
| Author | Kidani, Naoya| Sugiu, Kenji| Terasaka, Kaoru| Nakashima, Hiroyuki| Tokunaga, Koji| Kobayashi, Kazuki| Kambara, Hirokazu| Hishikawa, Tomohito| Hiramatsu, Masafumi| Date, Isao| |
| Note | This version of the article has been accepted for publication, after peer review (when applicable) and is subject to Springer Nature’s AM terms of use, but is not the Version of Record and does not reflect post-acceptance improvements, or any corrections. The Version of Record is available online at: https://doi.org/10.1007/s00701-021-04885-1| |
| Published Date | 2021-6-19 |
| Publication Title | Acta Neurochirurgica |
| Volume | volume164 |
| Issue | issue2 |
| Publisher | Springer Science and Business Media LLC |
| Start Page | 517 |
| End Page | 523 |
| ISSN | 0001-6268 |
| NCID | AA0050885X |
| Content Type | Journal Article |
| language | English |
| OAI-PMH Set | 岡山大学 |
| File Version | author |
| PubMed ID | 34146152 |
| DOI | 10.1007/s00701-021-04885-1 |
| Web of Science KeyUT | 000663495400001 |
| Related Url | isVersionOf https://doi.org/10.1007/s00701-021-04885-1 |
| FullText URL | fulltext.pdf |
|---|---|
| Author | Kageyama, Misaki| Hagiya, Hideharu| Ueda, Yasutaka| Ohtani, Katsuki| Fukumori, Yasuo| Inoue, Norimitsu| Wakamiya, Nobutaka| Yoneda, Nanoka| Kimura, Keigo| Nagasawa, Motonori| Nakagami, Futoshi| Nishi, Isao| Sugimoto, Ken| Rakugi, Hiromi| |
| Keywords | complement addition test complement deficiency disseminated gonococcal infection genome analysis Neisseria gonorrhoeae sexually transmitted infection |
| Published Date | 2021-04-02 |
| Publication Title | Medicine |
| Volume | volume100 |
| Issue | issue13 |
| Publisher | LIPPINCOTT WILLIAMS & WILKINS |
| Start Page | e25265 |
| ISSN | 0025-7974 |
| Content Type | Journal Article |
| language | English |
| OAI-PMH Set | 岡山大学 |
| Copyright Holders | © 2021 the Author(s). |
| File Version | publisher |
| PubMed ID | 33787610 |
| DOI | 10.1097/MD.0000000000025265 |
| NAID | 120007098535 |
| Web of Science KeyUT | 000658960700045 |
| Related Url | isVersionOf https://doi.org/10.1097/MD.0000000000025265 |
| JaLCDOI | 10.18926/AMO/62237 |
|---|---|
| FullText URL | 75_3_397.pdf |
| Author | Sekito, Takanori| Takamoto, Atsushi| Kobayashi, Yasuyuki| Mitsui, Masao| Watari, Shogo| Kubota, Risa| Sadahira, Takuya| Iwata, Takehiro| Nishimura, Shingo| Edamura, Kohei| Sako, Tomoko| Araki, Motoo| Watanabe, Masami| Watanabe, Toyohiko| Shibata, Rei| Ennishi, Daisuke| Nasu, Yasutomo| |
| Abstract | We report a 62-year-old male with metastatic fumarate hydratase-deficient renal cell carcinoma (FH-deficient RCC) without fumarate hydratase (FH) mutation (FH-deficient–like RCC). The International Metastatic RCC Database Consortium risk score was intermediate, and immunotherapy with nivolumab and ipilimumab (Ipi/ Nivo) was initiated. Four cycles of Ipi/Nivo and 5 cycles of nivolumab resulted in a complete response of the metastases. Hypophysitis occurred as an immune-related adverse event after four cycles of Ipi/Nivo. The prognosis of patients with FH-deficient RCC is generally poor. Few reports of FH-deficient RCC successfully treated with Ipi/Nivo have been published. Ipi/Nivo can be effective for treating FH-deficient RCC. |
| Keywords | fumarate hydratase fumarate hydratase-deficient renal cell carcinoma renal cell carcinoma ipilimumab nivolumab |
| Amo Type | Case Report |
| Publication Title | Acta Medica Okayama |
| Published Date | 2021-06 |
| Volume | volume75 |
| Issue | issue3 |
| Publisher | Okayama University Medical School |
| Start Page | 397 |
| End Page | 402 |
| ISSN | 0386-300X |
| NCID | AA00508441 |
| Content Type | Journal Article |
| language | English |
| Copyright Holders | CopyrightⒸ 2021 by Okayama University Medical School |
| File Version | publisher |
| Refereed | True |
| PubMed ID | 34176946 |
| Web of Science KeyUT | 000667147700017 |
| NAID | 120007089822 |
| JaLCDOI | 10.18926/AMO/62236 |
|---|---|
| FullText URL | 75_3_391.pdf |
| Author | Fujiwara, Miyuki| Kimura, Shuhei| Morizane Hosokawa, Mio| Shiode, Yusuke| Doi, Shinichiro| Takahashi, Kosuke| Matoba, Ryo| Kanzaki, Yuki | Morizane, Yuki| |
| Abstract | A 58-year-old Japanese man underwent vitrectomy for rhegmatogenous retinal detachment (RRD) in 2002. Twelve years later, optical coherence tomography revealed the development of a lamellar macular hole; the visual acuity was 20/200. Two years later, because metamorphopsia and the foveal retina thinning were aggravated, epiretinal proliferation embedding was performed to restore the foveal structure by transplanting glial cells to the foveal cavity. The patient was followed-up for 4 years, and his macular morphology and visual acuity (20/66) improved. No complications occurred. This appears to be the first report of epiretinal proliferation embedding for a lamellar macular hole post-RRD repair. |
| Amo Type | Case Report |
| Publication Title | Acta Medica Okayama |
| Published Date | 2021-06 |
| Volume | volume75 |
| Issue | issue3 |
| Publisher | Okayama University Medical School |
| Start Page | 391 |
| End Page | 395 |
| ISSN | 0386-300X |
| NCID | AA00508441 |
| Content Type | Journal Article |
| language | English |
| Copyright Holders | CopyrightⒸ 2021 by Okayama University Medical School |
| File Version | publisher |
| Refereed | True |
| PubMed ID | 34176945 |
| Web of Science KeyUT | 000667147700016 |
| NAID | 120007089821 |
| JaLCDOI | 10.18926/AMO/62234 |
|---|---|
| FullText URL | 75_3_381.pdf |
| Author | Yamamoto, Ken-ichi| Oshiki, Toshiyuki| Kagawa, Hiroko| Namba, Masayoshi| Sakaguchi, Masakiyo| |
| Abstract | The worldwide microplastic pollution in our environment is a matter of great concern. Harmful effects of plastics have been reported in various types of organisms including murine animals. We examined the presence of microplastics in four types of shellfish purchased from fish markets in Okayama, Japan and served to the public: short-neck clam (Ruditapes philippinarum, asari in Japanese), hard-shell clam (Meretrix lusoria, hamaguri), brackishwater clam (Cyrenidae, shijimi), and oyster (Crassostrea gigas, kaki). Our analyses demonstrated that approx. 3 pieces of microplastics were present per single shellfish, based on the division of the total number of pieces of microplastic obtained from all 4 types of shellfish by the total number of shellfish examined. Since health problems in humans due to microplastics have not yet been confirmed, further examinations of the effects of ingested microplastics are needed. |
| Keywords | microplastics, shellfish Japan health effect pollution |
| Amo Type | Short Communication |
| Publication Title | Acta Medica Okayama |
| Published Date | 2021-06 |
| Volume | volume75 |
| Issue | issue3 |
| Publisher | Okayama University Medical School |
| Start Page | 381 |
| End Page | 384 |
| ISSN | 0386-300X |
| NCID | AA00508441 |
| Content Type | Journal Article |
| language | English |
| Copyright Holders | CopyrightⒸ 2021 by Okayama University Medical School |
| File Version | publisher |
| Refereed | True |
| PubMed ID | 34176943 |
| Web of Science KeyUT | 000667147700014 |
| NAID | 120007089831 |
| JaLCDOI | 10.18926/AMO/62226 |
|---|---|
| FullText URL | 75_3_315.pdf |
| Author | Wada, Riho| Fujiwara, Masaki| Yamada, Yuto| Nakaya, Naoki| Fujimori, Maiko| So, Ryuhei| Kodama, Masafumi| Higuchi, Yuji| Kakeda, Kyoko| Uchitomi, Yosuke| Yamada, Norihito| Inagaki, Masatoshi| |
| Abstract | It is necessary to assess functional impairment when treating schizophrenia. The World Health Organization Disability Assessment Schedule 2.0 (WHODAS 2.0) has been adopted as a measure of functional disability in the Diagnostic and Statistical Manual of Mental Disorders, Fifth Edition. This study was a secondary analysis from a cross-sectional study of health-related behaviors among patients with schizophrenia. We examined the validity and reliability of the Japanese version of the 12-item WHODAS 2.0 when self-administered by such patients. Participants were 350 outpatients with schizophrenia from a psychiatric hospital. The standard six-factor structure of the WHODAS 2.0 showed a good fit for these participants. The Cronbach’s alpha coefficient was 0.858, showing good internal consistency. The WHODAS 2.0 showed moderate correlations with the modified Global Assessment of Functioning and Kessler 6 scales (r=−0.434 and 0.555, respectively). The results of this study show that the Japanese version of the 12-item self-administered WHODAS 2.0 has good internal consistency and convergent validity among patients with schizophrenia. Further exploration of the usefulness of WHODAS 2.0 in clinical settings is needed. |
| Keywords | disability schizophrenia validity reliability WHODAS 2.0 |
| Amo Type | Original Article |
| Publication Title | Acta Medica Okayama |
| Published Date | 2021-06 |
| Volume | volume75 |
| Issue | issue3 |
| Publisher | Okayama University Medical School |
| Start Page | 315 |
| End Page | 322 |
| ISSN | 0386-300X |
| NCID | AA00508441 |
| Content Type | Journal Article |
| language | English |
| Copyright Holders | CopyrightⒸ 2021 by Okayama University Medical School |
| File Version | publisher |
| Refereed | True |
| PubMed ID | 34176935 |
| NAID | 120007089823 |
| JaLCDOI | 10.18926/AMO/62225 |
|---|---|
| FullText URL | 75_3_307.pdf |
| Author | Ishizaka, Hinata| Kuroda, Masahiro| Tekiki, Nouha| Khasawneh, Abdullah| Barham, Majd| Hamada, Kentaro| Konishi, Kohei| Sugimoto, Kohei| Katsui, Kuniaki| Sugiyama, Soichi| Watanabe, Kenta| Yoshio, Kotaro | Katayama, Norihisa| Ogata, Takeshi| Ihara, Hiroki| Oita, Masataka| Kanazawa, Susumu| Asaumi, Junichi| |
| Abstract | Reports on irradiation dose distribution in breast cancer radiotherapy with sufficient sample size are limited in Asian patients. Elucidating dose distribution in Asian patients is particularly important as their breast volume differs compared to patients in Europe and North America. Here, we examined dose distribution in the irradiation field relative to breast volume for three irradiation methods historically used in our facility. We investigated the influence of breast volume on each irradiation method for Asian women. A total of 573 women with early-stage breast cancer were treated with breast-conserving surgery and adjuvant radiotherapy. Three methods were compared: wedge (W), field-in-field (FIF), and wedge-field-in-field (W-FIF). In patients with small breast volume, FIF decreased low- and high-dose areas within the planning target volume, and increased optimal dose area more than W. In patients with medium and large breast volumes, FIF decreased high-dose area more than W. The absolute values of correlation coefficients of breast volume to low-, optimal-, and high-dose areas and mean dose were significantly lower in FIF than in W. The correlation coefficients of V107% were 0.00 and 0.28 for FIF and W, respectively. FIF is an excellent irradiation method that is less affected by breast volume than W in Asian breast cancer patients. |
| Keywords | breast cancer radiotherapy dose distribution irradiation method breast volume |
| Amo Type | Original Article |
| Publication Title | Acta Medica Okayama |
| Published Date | 2021-06 |
| Volume | volume75 |
| Issue | issue3 |
| Publisher | Okayama University Medical School |
| Start Page | 307 |
| End Page | 314 |
| ISSN | 0386-300X |
| NCID | AA00508441 |
| Content Type | Journal Article |
| language | English |
| Copyright Holders | CopyrightⒸ 2021 by Okayama University Medical School |
| File Version | publisher |
| Refereed | True |
| PubMed ID | 34176934 |
| Web of Science KeyUT | 000667147700006 |
| NAID | 120007089838 |
| JaLCDOI | 10.18926/AMO/62221 |
|---|---|
| FullText URL | 75_3_299.pdf |
| Author | Araki, Jo| Oka, Kosuke| Yamamoto, Koichiro| Hanayama, Yoshihisa | Tokumasu, Kazuki| Hagiya, Hideharu| Ogawa, Hiroko| Itoshima, Koichi| Otsuka, Fumio| |
| Abstract | Various laboratory markers of inflammation are utilized in general practice, but their clinical diagnostic significance is often ambiguous. In the present study, we determined the clinical significance of the examination of serum levels of procalcitonin (PCT) by comparing the PCT levels with the levels of other inflammatory markers, based on a retrospective review of 332 PCT-positive patients, including cases of bacterial infection (20.5%), non-specific inflammation (20.8%), neoplasm (9.9%), connective tissue diseases (8.4%), and non-bacterial infection (7.2%), were analyzed. The serum PCT level was highest in the bacterial infection group (1.94 ng/ml) followed by the non-specific inflammatory group (0.58 ng/ml) and neoplastic diseases group (0.34 ng/ml). The serum PCT level was positively correlated with serum levels of C-reactive protein (rho=0.62), soluble interleukin-2 receptor (sIL-2R; rho=0.69), and ferritin, the plasma level of D-dimer, and white blood cell count, and negatively correlated with the serum albumin level (rho=−0.52), hemoglobin concentration, and platelet count. The serum PCT level showed a stronger positive correlation with the serum sIL-2R level than the other biomarkers. The results suggest that an increased PCT level may indicate not only an infectious state but also a non-bacterial inflammatory condition in the diagnostic process in general practice. |
| Keywords | bacterial infection inflammation malignant lymphoma procalcitonin soluble interleukin-2 receptor |
| Amo Type | Original Article |
| Publication Title | Acta Medica Okayama |
| Published Date | 2021-06 |
| Volume | volume75 |
| Issue | issue3 |
| Publisher | Okayama University Medical School |
| Start Page | 299 |
| End Page | 306 |
| ISSN | 0386-300X |
| NCID | AA00508441 |
| Content Type | Journal Article |
| language | English |
| Copyright Holders | CopyrightⒸ 2021 by Okayama University Medical School |
| File Version | publisher |
| Refereed | True |
| PubMed ID | 34176933 |
| Web of Science KeyUT | 000667147700005 |
| NAID | 120007089836 |
| JaLCDOI | 10.18926/AMO/62220 |
|---|---|
| FullText URL | 75_3_289.pdf |
| Author | Miyamoto, Masakazu| Osawa, Kazuhiro| Miyoshi, Toru| Mori, Atsushi| Yoshikawa, Masaki| Oka, Takefumi| Ichikawa, Keishi| Nakamura, Kazufumi| Ito, Hiroshi| |
| Abstract | Early treatment with an oral β-blocker is recommended in patients with a ST-segment–elevation myocardial infarction (STEMI). In this multicenter study, we evaluated the effects of a continuous administration of landiolol, an ultrashort-acting β-blocker, before primary percutaneous coronary intervention (PCI) on myocardial salvage and its safety in STEMI patients. A total of 47 Japanese patients with anterior or lateral STEMI undergoing a primary PCI within 12 h of symptom onset were randomized to receive intravenous landiolol (started at 3 μg/min/kg dose and continued to a total of 50 mg; n=23) or not (control; n=24). Patients with Killip class III or more were excluded. The primary outcome was the myocardial salvage index on cardiac magnetic resonance imaging (MRI) performed 5-7 days after the PCI. Cardiac MRI was performed in 35 patients (74%). The myocardial salvage index in the landiolol group was significantly greater than that in the control group (44.4±14.6% vs. 31.7±18.9%, respectively; p=0.04). There were no significant differences in adverse events at 24 h between the landiolol and control groups. A continuous administration of landiolol before a primary PCI may increase the degree of myocardial salvage without additional hemodynamic adverse effects within the first 24 h after STEMI. |
| Keywords | myocardial infarction landiolol magnetic resonance imaging STEMI PCI |
| Amo Type | Original Article |
| Publication Title | Acta Medica Okayama |
| Published Date | 2021-06 |
| Volume | volume75 |
| Issue | issue3 |
| Publisher | Okayama University Medical School |
| Start Page | 289 |
| End Page | 297 |
| ISSN | 0386-300X |
| NCID | AA00508441 |
| Content Type | Journal Article |
| language | English |
| Copyright Holders | CopyrightⒸ 2021 by Okayama University Medical School |
| File Version | publisher |
| Refereed | True |
| PubMed ID | 34176932 |
| Web of Science KeyUT | 000667147700004 |
| NAID | 120007089835 |
| JaLCDOI | 10.18926/AMO/62219 |
|---|---|
| FullText URL | 75_3_279.pdf |
| Author | Nishinohara, Masa-aki| Nishimori, Hisakazu| Fujiwara, Hideaki| Asada, Noboru| Ennishi, Daisuke| Matsuoka, Ken-ichi| Fujii, Keiko| Fujii, Nobuharu| Maeda, Yoshinobu| |
| Abstract | A bloodstream infection (BSI) is the most common serious infectious complication of hematopoietic stem cell transplantation (HSCT). BSI promotes an inflammatory state, which exacerbates acute graft-versus-host disease (GVHD). We investigated whether a Gram-negative rod bloodstream infection (GNR-BSI), which develops early after allo-HSCT, affected the onset or exacerbated acute GVHD in 465 patients who underwent allo-HSCT from 1995 through 2015 at a single institution. Eighty-eight patients (19%) developed BSI during the study period. Among the cultures, 50 (57%) were Gram-positive cocci (GPC) and 31 (35%) were GNR. Of the 465 patients, 187 (40%) developed acute GVHD of grade II or higher within the first 100 days post-allogeneic HSCT: 124 (27%) had acute GVHD grade II, 47 (10%) had grade III, and 16 (3%) had grade IV. Multivariate analysis revealed that GNR-BSI was a significant risk factor for grade II-IV acute GVHD (grade II-IV: hazard ratio [HR] 1.75, 95% confidence interval [CI] 1.03-2.97; grade III-IV: HR 2.37, 95% CI 1.03-5.43). These results suggest that GNR-BSI may predict the onset and exacerbation of acute GVHD. |
| Keywords | blood stream infection graft-versus-host disease gram negative rods |
| Amo Type | Original Article |
| Publication Title | Acta Medica Okayama |
| Published Date | 2021-06 |
| Volume | volume75 |
| Issue | issue3 |
| Publisher | Okayama University Medical School |
| Start Page | 279 |
| End Page | 287 |
| ISSN | 0386-300X |
| NCID | AA00508441 |
| Content Type | Journal Article |
| language | English |
| Copyright Holders | CopyrightⒸ 2021 by Okayama University Medical School |
| File Version | publisher |
| Refereed | True |
| PubMed ID | 34176931 |
| Web of Science KeyUT | 000667147700003 |
| NAID | 120007089834 |
| JaLCDOI | 10.18926/AMO/62218 |
|---|---|
| FullText URL | 75_3_269.pdf |
| Author | Katsui, Kuniaki| Ogata, Takeshi| Watanabe, Kenta| Yoshio, Kotaro| Kuroda, Masahiro| Hiraki, Takao| Kiura, Katsuyuki| Maeda, Yoshinobu| Toyooka, Shinichi| Kanazawa, Susumu| |
| Abstract | Palliative concurrent chemoradiotherapy (CCRT) is often administered to patients with stage III non-small cell lung cancer (NSCLC). We investigated the clinical outcomes of patients receiving palliative CCRT for NSCLC. Data of patients with NSCLC who underwent palliative CCRT (n=16), preoperative CCRT plus surgery (n=97), or definitive CCRT (n=48) were evaluated. In all groups, the concurrent chemotherapy regimens consisted of cisplatin and docetaxel. Rates of local control (LC), distant metastasis-free survival (DMFS), progression-free survival (PFS), overall survival (OS), and prognosis were compared. The 2-year rates of LC, DMFS, PFS, and OS in 16 patients who underwent palliative CCRT were 44.4%, 12.5%, 12.5%, and 18.8%, respectively. Univariate analysis showed that palliative CCRT was associated with poor LC (p<0.001), DMFS (p<0.001), PFS (p<0.001), and OS (p<0.001) outcomes in patients who completed CCRT as a preoperative treatment and poor LC (p=0.01), DMFS (p=0.003), PFS (p=0.04), and OS (p=0.004) outcomes in patients who were considered for definitive CCRT. Although there were some long-term survivors, the clinical outcomes of palliative CCRT were significantly inferior to those of the ideal treatments. Therefore, careful determination of the appropriate treatment indications and further studies are warranted. |
| Keywords | palliative concurrent chemoradiotherapy cisplatin/docetaxel stage III non-small cell lung cancer |
| Amo Type | Original Article |
| Publication Title | Acta Medica Okayama |
| Published Date | 2021-06 |
| Volume | volume75 |
| Issue | issue3 |
| Publisher | Okayama University Medical School |
| Start Page | 269 |
| End Page | 277 |
| ISSN | 0386-300X |
| NCID | AA00508441 |
| Content Type | Journal Article |
| language | English |
| Copyright Holders | CopyrightⒸ 2021 by Okayama University Medical School |
| File Version | publisher |
| Refereed | True |
| PubMed ID | 34176930 |
| Web of Science KeyUT | 000667147700002 |
| NAID | 120007089833 |
| FullText URL | fulltext.pdf |
|---|---|
| Author | Kuroda, Kosuke| Ishii, Kenzo| Mihara, Yuko| Kawanoue, Naoya| Wake, Hidenori| Mori, Shuji| Yoshida, Michihiro| Nishibori, Masahiro| Morimatsu, Hiroshi| |
| Published Date | 2021-05-13 |
| Publication Title | Scientific Reports |
| Volume | volume11 |
| Issue | issue1 |
| Publisher | Nature Research |
| Start Page | 10223 |
| ISSN | 2045-2322 |
| Content Type | Journal Article |
| language | English |
| OAI-PMH Set | 岡山大学 |
| Copyright Holders | © The Author(s) 2021 |
| File Version | publisher |
| PubMed ID | 33986340 |
| DOI | 10.1038/s41598-021-89555-z |
| NAID | 120007053368 |
| Web of Science KeyUT | 000656946100013 |
| Related Url | isVersionOf https://doi.org/10.1038/s41598-021-89555-z |
| FullText URL | fulltext.pdf |
|---|---|
| Author | Mise, Koki| Imamura, Mariko| Yamaguchi, Satoshi| Watanabe, Mayu| Higuchi, Chigusa| Katayama, Akihiro| Miyamoto, Satoshi| Uchida, Haruhito A.| Nakatsuka, Atsuko| Eguchi, Jun| Hida, Kazuyuki| Nakato, Tatsuaki| Tone, Atsuhito| Teshigawara, Sanae| Matsuoka, Takashi| Kamei, Shinji| Murakami, Kazutoshi| Shimizu, Ikki| Miyashita, Katsuhiro| Ando, Shinichiro| Nunoue, Tomokazu| Yoshida, Michihiro| Yamada, Masao| Shikata, Kenichi| Wada, Jun| |
| Keywords | cardiovascular event diabetes lectins N-glycans urinary biomarkers |
| Published Date | 2021-05-24 |
| Publication Title | Frontiers In Cardiovascular Medicine |
| Volume | volume8 |
| Publisher | Frontiers Media SA |
| Start Page | 668059 |
| ISSN | 2297-055X |
| Content Type | Journal Article |
| language | English |
| OAI-PMH Set | 岡山大学 |
| Copyright Holders | © 2021 by the authors. |
| File Version | publisher |
| PubMed ID | 34109226 |
| DOI | 10.3389/fcvm.2021.668059 |
| NAID | 120007053373 |
| Web of Science KeyUT | 000658156400001 |
| Related Url | isVersionOf https://doi.org/10.3389/fcvm.2021.668059 |
| FullText URL | fulltext20210607-4.pdf table1-20210607-4.pdf table2-20210607-4.pdf figure-20210607-4.pdf |
|---|---|
| Author | Kikuchi, Satoru| Kagawa, Tetsuya| Kuroda, Shinji| Nishizaki, Masahiko| Takata, Nobuo| Kuwada, Kazuya| Shoji, Ryohei| Kakiuchi, Yoshihiko| Mitsuhashi, Toshiharu| Umeda, Yuzo| Noma, Kazuhiro| Kagawa, Shunsuke| Fujiwara, Toshiyoshi| |
| Keywords | Endoscopic surgical skill quantification system Qualified surgeon Laparoscopic distal gastrectomy Gastric cancer Cumulative sum analysis |
| Note | This is a post-peer-review, pre-copyedit version of an article published in [Surgery Today]. The final authenticated version is available online at: http://dx.doi.org/10.1007/s00595-021-02309-2| |
| Published Date | 2021-5-29 |
| Publication Title | Surgery Today |
| Volume | volume51 |
| Publisher | Springer Science and Business Media LLC |
| Start Page | 1978 |
| End Page | 1984 |
| ISSN | 0941-1291 |
| NCID | AA10824685 |
| Content Type | Journal Article |
| language | English |
| OAI-PMH Set | 岡山大学 |
| Copyright Holders | © Springer Nature Singapore Pte Ltd. 2021 |
| File Version | author |
| PubMed ID | 34050804 |
| DOI | 10.1007/s00595-021-02309-2 |
| Web of Science KeyUT | 000655944300001 |
| Related Url | isVersionOf https://doi.org/10.1007/s00595-021-02309-2 |
| FullText URL | fulltext20210608.pdf |
|---|---|
| Author | Umeda, Hibiki| Kikuchi, Satoru| Kuroda, Shinji| Yano, Shuya| Tanaka, Takehiro| Noma, Kazuhiro| Nishizaki, Masahiko| Kagawa, Shunsuke| Umeda, Yuzo| Fujiwara, Toshiyoshi| |
| Keywords | Gastric yolk sac Tumor-like carcinoma Adenocarcinoma Alpha-fetoprotein |
| Published Date | 2021-05-06 |
| Publication Title | Surgical Case Reports |
| Volume | volume7 |
| Issue | issue1 |
| Publisher | Springer |
| Start Page | 111 |
| ISSN | 2198-7793 |
| Content Type | Journal Article |
| language | English |
| OAI-PMH Set | 岡山大学 |
| Copyright Holders | © The Author(s) 2021. |
| File Version | publisher |
| PubMed ID | 33956241 |
| DOI | 10.1186/s40792-021-01199-3 |
| NAID | 120007045008 |
| Web of Science KeyUT | 000656467700001 |
| Related Url | isVersionOf https://doi.org/10.1186/s40792-021-01199-3 |
