result 3928 件
| JaLCDOI | 10.18926/AMO/55864 |
|---|---|
| FullText URL | 72_2_203.pdf |
| Author | Sonekatsu, Mayumi| Sonohata, Motoki| Kitajima, Masaru| Kawano, Shunsuke| Mawatari, Masaaki| |
| Abstract | In the article by Sonekatsu M et al. entitled “Total Hip Arthroplasty for Patients with Residual Poliomyelitis at a Mean Eight Years of Follow-up”, which appeared in the February 2018 issue, Vol.72, No.1, pp17-22, following corrections should be listed. Editorial Office sincerely apologizes for making mistakes in the previous galley proof, therefore republish a corrected version. |
| Amo Type | Erratum with Corrected and Republished Article |
| Publication Title | Acta Medica Okayama |
| Published Date | 2018-04 |
| Volume | volume72 |
| Issue | issue2 |
| Publisher | Okayama University Medical School |
| Start Page | 203 |
| End Page | 210 |
| ISSN | 0386-300X |
| NCID | AA00508441 |
| Content Type | Journal Article |
| language | English |
| Copyright Holders | CopyrightⒸ 2018 by Okayama University Medical School |
| File Version | publisher |
| Refereed | True |
| PubMed ID | 29674772 |
| Related Url | replaces http://doi.org/10.18926/AMO/55658 |
| JaLCDOI | 10.18926/AMO/55863 |
|---|---|
| FullText URL | 72_2_197_n.pdf |
| Author | Takase, Ken| Kada, Akiko| Iwasaki, Hiromi| Yoshida, Isao| Sawamura, Morio| Yoshio, Nobuyuki| Yoshida, Shinichiro| Iida, Hiroatsu| Otsuka, Maki| Takafuta, Toshiro| Ogata, Yuko| Suehiro, Youko| Hirabayashi, Yukio| Hishita, Terutoshi| Yoshida, Chikamasa| Ito, Takuo| Hidaka, Michihiro| Tsutsumi, Ikuyo| Saito, Akiko M.| Nagai, Hirokazu| |
| Abstract | Standard therapy for idiopathic thrombocytopenic purpura (ITP) has not been established. We are conducting a multicenter, prospective trial to determine the efficacy and safety of short-term, high-dose dexamethasone therapy in ITP patients aged 18-80 years with platelet counts of <20, 000 /μL, or with <50, 000/ μL and bleeding symptoms. The primary endpoints of this trial are the proportion of responses (complete plus partial response) on day 180 (day 46+180) after the completion of the 46-day high-dose dexamethasone therapy. The results of this investigation of the effectiveness and safety of this regimen will be essential for the establishment of standard therapy for ITP. |
| Keywords | idiopathic thrombocytopenic purpura short-term high-dose dexamethasone therapy open-label single-arm trial |
| Amo Type | Clinical Study Protocol |
| Publication Title | Acta Medica Okayama |
| Published Date | 2018-04 |
| Volume | volume72 |
| Issue | issue2 |
| Publisher | Okayama University Medical School |
| Start Page | 197 |
| End Page | 201 |
| ISSN | 0386-300X |
| NCID | AA00508441 |
| Content Type | Journal Article |
| language | English |
| Copyright Holders | CopyrightⒸ 2018 by Okayama University Medical School |
| File Version | publisher |
| Refereed | True |
| PubMed ID | 29674771 |
| JaLCDOI | 10.18926/AMO/55862 |
|---|---|
| FullText URL | 72_2_193.pdf |
| Author | Shioji, Naohiro| Kanazawa, Tomoyuki| Iwasaki, Tatsuo| Shimizu, Kazuyoshi| Suemori, Tomohiko| Kawase, Hirokazu| Kimura, Satoshi| Kuroe, Yasutoshi| Morimatsu, Hiroshi| |
| Abstract | We will investigate the incidence of postoperative pulmonary complications (PPCs) with the prophylactic use of a high-flow nasal cannula (HFNC) after pediatric cardiac surgery. Children < 48 months old with congenital heart disease for whom cardiac surgery is planned will be included. The HFNC procedure will be commenced just after extubation, at a flow rate of 2 L/kg/min with adequate oxygen concentration to achieve target oxygen saturation ≥ 94%. This study will reveal the prevalence of PPCs after pediatric cardiac surgery with the prophylactic use of HFNC. |
| Keywords | high-flow nasal cannula postoperative pulmonary complications pediatric cardiac surgery congenital heart disease |
| Amo Type | Clinical Study Protocol |
| Publication Title | Acta Medica Okayama |
| Published Date | 2018-04 |
| Volume | volume72 |
| Issue | issue2 |
| Publisher | Okayama University Medical School |
| Start Page | 193 |
| End Page | 196 |
| ISSN | 0386-300X |
| NCID | AA00508441 |
| Content Type | Journal Article |
| language | English |
| Copyright Holders | CopyrightⒸ 2018 by Okayama University Medical School |
| File Version | publisher |
| Refereed | True |
| PubMed ID | 29674770 |
| JaLCDOI | 10.18926/AMO/55861 |
|---|---|
| FullText URL | 72_2_189.pdf |
| Author | Nakao, Shinichiro| Hagiya, Hideharu| Kimura, Keigo| Mitsui, Tomomi| Oyama, Akane| Hongyo, Kazuhiro| Takahashi, Yusuke| Nakagami, Futoshi| Tomono, Kazunori| Rakugi, Hiromi| |
| Abstract | A 65-year-old Japanese man with bilateral carotid atherosclerosis presented with right neck pain and fever. Contrast-enhanced computed tomography suggested carotid arteritis, and carotid ultrasonography showed an unstable plaque. The patient developed a cerebral embolism, causing a transient ischemic attack. Helicobacter cinaedi was detected in blood culture, and H. cinaedi-associated carotid arteritis was diagnosed. Empirical antibiotic therapy was administered for 6 weeks. After readmission for recurrent fever, he was treated another 8 weeks. Although the relationship between H. cinaedi infection and atherosclerosis development remains unclear, the atherosclerotic changes in our patient’s carotid artery might have been attributable to H. cinaedi infection. |
| Keywords | atherosclerosis bacteremia bacterial translocation Helicobacter cinaedi vascular infection |
| Amo Type | Case Report |
| Publication Title | Acta Medica Okayama |
| Published Date | 2018-04 |
| Volume | volume72 |
| Issue | issue2 |
| Publisher | Okayama University Medical School |
| Start Page | 189 |
| End Page | 192 |
| ISSN | 0386-300X |
| NCID | AA00508441 |
| Content Type | Journal Article |
| language | English |
| Copyright Holders | CopyrightⒸ 2018 by Okayama University Medical School |
| File Version | publisher |
| Refereed | True |
| PubMed ID | 29674769 |
| JaLCDOI | 10.18926/AMO/55860 |
|---|---|
| FullText URL | 72_2_185.pdf |
| Author | Morizane, Shin| Sugimoto, Saeko| Motoki, Takayuki| Katayama, Norihisa| Omori, Masako| Iwatsuki, Keiji| |
| Abstract | Psoriasis is a common chronic inflammatory skin disorder that is characterized by scaly, erythematous, sharply demarcated plaques. The treatment for psoriasis has dramatically changed over the last 10 years with the introduction of biologics. However, the risk of cancer induced by biologics for psoriasis has not been fully analyzed, since these agents have such a short history of use. Here we report the case of a 74-year-old woman with psoriasis vulgaris and psoriatic arthritis complicated by breast cancer after systemic treatments including etretinate, cyclosporine, methotrexate, adalimumab, and ustekinumab. |
| Keywords | psoriasis systemic therapy biologics malignancy |
| Amo Type | Case Report |
| Publication Title | Acta Medica Okayama |
| Published Date | 2018-04 |
| Volume | volume72 |
| Issue | issue2 |
| Publisher | Okayama University Medical School |
| Start Page | 185 |
| End Page | 187 |
| ISSN | 0386-300X |
| NCID | AA00508441 |
| Content Type | Journal Article |
| language | English |
| Copyright Holders | CopyrightⒸ 2018 by Okayama University Medical School |
| File Version | publisher |
| Refereed | True |
| PubMed ID | 29674768 |
| JaLCDOI | 10.18926/AMO/55859 |
|---|---|
| FullText URL | 72_2_181.pdf |
| Author | Tsuboi, Chika| Naito, Hiromichi| Hagioka, Shingo| Hanafusa, Hiroaki| Hirayama, Takahiro| Kosaki, Yoshinori| Iida, Atsuyoshi| Yumoto, Tetsuya| Tsukahara, Kohei| Morimoto, Naoki| Nakao, Atsunori| |
| Abstract | The primary toxicity of hydrogen peroxide results from its interaction with catalase, which liberates water and oxygen. We report the case of a 14-year-old Japanese girl with portal venous gas that was caused by oxygen liberated from intentionally ingested hydrogen peroxide. Although she had a past history of atrial septal defect, recovery without cardiac or neurological sequelae was achieved using hyperbaric oxygen therapy. Emergency physicians must be aware of the danger of liberated oxygen due to hydrogen peroxide ingestion. |
| Keywords | air embolism ASD breaching agent HBO intoxication |
| Amo Type | Case Report |
| Publication Title | Acta Medica Okayama |
| Published Date | 2018-04 |
| Volume | volume72 |
| Issue | issue2 |
| Publisher | Okayama University Medical School |
| Start Page | 181 |
| End Page | 183 |
| ISSN | 0386-300X |
| NCID | AA00508441 |
| Content Type | Journal Article |
| language | English |
| Copyright Holders | CopyrightⒸ 2018 by Okayama University Medical School |
| File Version | publisher |
| Refereed | True |
| PubMed ID | 29674767 |
| JaLCDOI | 10.18926/AMO/55858 |
|---|---|
| FullText URL | 72_2_175.pdf |
| Author | Hirata, Takeshi| Hanamoto, Masanori| Ogura, Kazuma| Hayashi, Nobuki| Takamura, Kosuke| Edamura, Kohei| Ebara, Shin| Saika, Takashi| |
| Abstract | There is no standard second-line or salvage treatment for advanced urothelial carcinoma (UC). Here we investigated the efficacy and safety of gemcitabine, cisplatin, and paclitaxel (GCP) combination chemotherapy as salvage chemotherapy for advanced UC. We retrospectively analyzed the cases of 23 patients with advanced UC who showed progression or recurrence after cisplatin-based chemotherapy. Gemcitabine (1000 mg/m2), and paclitaxel (80 mg/m2) were administered on days 1 and 8. Cisplatin (70 mg/m2) was administered on day 1. The 3-week cycle regimen was repeated until disease progression if it had no intolerable toxicity. The overall response rate was 61% (95%CI, 41-78%). The median overall survival and progression-free survival times were 14 months and 5.5 months, respectively. Of the already known risk factors of chemotherapy for advanced UC, only the performance status was a prognostic factor for OS. Overall, 16 of the 23 patients (70%) experienced grade 3/4 toxicities, and no fatal adverse events were observed. GCP therapy was a promising option as second-line or salvage therapy for advanced UC. |
| Keywords | urothelial carcinoma gemcitabine cisplatin paclitaxel second-line salvage |
| Amo Type | Original Article |
| Publication Title | Acta Medica Okayama |
| Published Date | 2018-04 |
| Volume | volume72 |
| Issue | issue2 |
| Publisher | Okayama University Medical School |
| Start Page | 175 |
| End Page | 179 |
| ISSN | 0386-300X |
| NCID | AA00508441 |
| Content Type | Journal Article |
| language | English |
| Copyright Holders | CopyrightⒸ 2018 by Okayama University Medical School |
| File Version | publisher |
| Refereed | True |
| PubMed ID | 29674766 |
| JaLCDOI | 10.18926/AMO/55857 |
|---|---|
| FullText URL | 72_2_165.pdf |
| Author | Yoshida, Aki| Fujiwara, Tomohiro| Uotani, Koji| Morita, Takuya| Kiyono, Masahiro| Yokoo, Suguru| Hasei, Joe| Nakata, Eiji| Kunisada, Toshiyuki| Ozaki, Toshifumi| |
| Abstract | Although there is considerable evidence indicating that the dysregulation of microRNAs (miRNAs) in malignant tumors plays a role in tumor development, the overall function of miRNAs and their clinicopathological significance are not well understood. In this retrospective analysis of 45 biopsy specimens from osteosarcoma (OS) patients, we investigated the functional and clinical significance of miR-25-3p in OS, which we previously identified as a highly expressed miRNA in OS patients’ serum. We observed that miR-25-3p dysregulation in human OS tissues was negatively correlated with the clinical prognosis, whereas the expression level of its target gene, Dickkopf WNT Signaling Pathway Inhibitor 3 (DKK3), was positively correlated with the clinical prognosis. Endogenous miR-25-3p upregulation promoted tumor growth, invasion, and drug resistance, which was consistent with DKK3 silencing in OS cells. In addition, secretory miR-25-3p was embedded in tumor-derived exosomes, where it promoted capillary formation and the invasion of vascular endothelial cells. Overall, our results show that miR-25-3p has intracellular and extracellular oncogenic functions as well as clinicopathological relevance in OS, indicating its potential as a novel diagnostic and therapeutic tool for the clinical management of this disease. |
| Keywords | microRNA circulating microRNA osteosarcoma prognosis |
| Amo Type | Original Article |
| Publication Title | Acta Medica Okayama |
| Published Date | 2018-04 |
| Volume | volume72 |
| Issue | issue2 |
| Publisher | Okayama University Medical School |
| Start Page | 165 |
| End Page | 174 |
| ISSN | 0386-300X |
| NCID | AA00508441 |
| Content Type | Journal Article |
| language | English |
| Copyright Holders | CopyrightⒸ 2018 by Okayama University Medical School |
| File Version | publisher |
| Refereed | True |
| PubMed ID | 29674765 |
| JaLCDOI | 10.18926/AMO/55856 |
|---|---|
| FullText URL | 72_2_153.pdf |
| Author | Kumashiro, Masayuki| Kataoka, Takahiro| Yokota, Shinobu| Nakagawa, Shinobu| Otsuki, Keisuke| Miyake, Nobuyuki| Osumi, Shinji| Yamaoka, Kiyonori| |
| Abstract | We examined the effects of a reduced exposure dose on the quality of images from an angiography device augmented with a noise reduction algorithm. Before its clinical application, we compared the diameter of the discrimination limit of the hole with that in the conventional method by a visual evaluation with a contrast-detail (C-D) phantom imaged using the target dose. Based on the results, a reducible dose was determined and applied clinically. The sample population consisted of patients being followed up after percutaneous coronary intervention (PCI) for coronary artery disease; we evaluated the effects of the exposure reduction on image quality. A significant dose reduction was observed by the noise-reduction method compared to the conventional method; the radiation dose to the flat panel detector (FPD) could be reduced to 70 nGy per frame. Clinically, a dose reduction of approx. 40% was obtained while maintaining image quality almost equal to that of the conventional method. |
| Keywords | image quality radiation dose noise reduction percutaneous coronary intervention contrast-detail phantom |
| Amo Type | Original Article |
| Publication Title | Acta Medica Okayama |
| Published Date | 2018-04 |
| Volume | volume72 |
| Issue | issue2 |
| Publisher | Okayama University Medical School |
| Start Page | 153 |
| End Page | 164 |
| ISSN | 0386-300X |
| NCID | AA00508441 |
| Content Type | Journal Article |
| language | English |
| Copyright Holders | CopyrightⒸ 2018 by Okayama University Medical School |
| File Version | publisher |
| Refereed | True |
| PubMed ID | 29674764 |
| JaLCDOI | 10.18926/AMO/55855 |
|---|---|
| FullText URL | 72_2_143.pdf |
| Author | Shinohara, Yoshie| Nakatsuka, Mikiya| |
| Abstract | We focus on Japanese individuals with gender identity disorder (GID), especially male-to-female (MTF) GID, who have experienced difficulty in adapting to social life. We clarify what gender dysphoria is, and we examine methods of intervention. Semi-structured interviews were conducted with 11 individuals with MTF-GID from August 2015 to April 2017. We categorized the subjects’experiences regarding dysphoria into the ‘Onset of gender dysphoria,’ ‘Experience of feeling gender dysphoria,’ and ‘Changes due to receiving medical care.’ The subjects reported experiencing great pain and distress because they did not fully understand that they were experiencing dysphoria and could not align their gender identity and their self-identity. All subjects described their experiences of dysphoria as negative. Additionally, all said that the dysphoria was alleviated by a medical intervention such as visiting a gender clinic, receiving a diagnosis and treatment, and changing their physical sex to the sex congruent with their gender identity. The provision of information at the gender clinic and the physical changes achieved by medical intervention exerted a positive effect both mentally and socially on the subjects, who suffered various physical, mental and social problems. |
| Keywords | gender identity disorder gender dysphoria gender identity male to female |
| Amo Type | Original Article |
| Publication Title | Acta Medica Okayama |
| Published Date | 2018-04 |
| Volume | volume72 |
| Issue | issue2 |
| Publisher | Okayama University Medical School |
| Start Page | 143 |
| End Page | 151 |
| ISSN | 0386-300X |
| NCID | AA00508441 |
| Content Type | Journal Article |
| language | English |
| Copyright Holders | CopyrightⒸ 2018 by Okayama University Medical School |
| File Version | publisher |
| Refereed | True |
| PubMed ID | 29674763 |
| JaLCDOI | 10.18926/AMO/55854 |
|---|---|
| FullText URL | 72_2_137.pdf |
| Author | Takahashi, Yuko| Shien, Tadahiko| Sakamoto, Ai| Tsuyumu, Yuko| Yoshioka, Ryo| Uno, Maya| Hatono, Minami| Kochi, Mariko| Kawada, Kengo| Tsukioki, Takahiro| Iwamoto, Takayuki| Ikeda, Hirokuni| Taira, Naruto| Matsuoka, Junji| Nakatsuka, Mikiya| Doihara, Hiroyoshi| |
| Abstract | Adverse effects on fertility are a significant problem for premenopausal breast cancer patients. Since April 2009, we have been referring young patients for fertility counseling provided by a multidisciplinary team. Here we evaluated the efficacy and safety of our current fertility preservation approach. We retrospectively analyzed the cases of 277 patients < 45 years old at diagnosis, which was made between 2009 and 2016. Seventy-two (26%) patients received fertility counseling. Seventeen (6%) of the 277 patients decided to preserve their fertility before starting adjuvant systemic therapy. Six (35%) patients underwent oocyte cryopreservation, and 11 (65%) married patients opted for embryo cryopreservation. There were no pregnancies among the patients undergoing oocyte cryopreservation, whereas 3 (27%) of the patients who opted for embryo cryopreservation became pregnant. Two (12%) patients stopped endocrine therapy after 2 years in an effort to become pregnant, but their breast cancers recurred. Though the problem of fertility loss for breast cancer patients is important and we should assess the infertility risk for all patients, we should also consider the prognosis. In June 2016, we launched a prospective multicenter cohort study to evaluate the efficacy and safety of fertility preservation in greater detail. |
| Keywords | fertility preservation multidisciplinary breast cancer young patients |
| Amo Type | Original Article |
| Publication Title | Acta Medica Okayama |
| Published Date | 2018-04 |
| Volume | volume72 |
| Issue | issue2 |
| Publisher | Okayama University Medical School |
| Start Page | 137 |
| End Page | 142 |
| ISSN | 0386-300X |
| NCID | AA00508441 |
| Content Type | Journal Article |
| language | English |
| Copyright Holders | CopyrightⒸ 2018 by Okayama University Medical School |
| File Version | publisher |
| Refereed | True |
| PubMed ID | 29674762 |
| JaLCDOI | 10.18926/AMO/55853 |
|---|---|
| FullText URL | 72_2_129.pdf |
| Author | Okura, Tomohiro| Fujii, Masakuni| Shiode, Junji| Ito, Yuri| Kojima, Toru| Nasu, Junichiro| Niguma, Takefumi| Yoshioka, Masao| Mimura, Tetsushige| Yamamoto, Kazuhide| |
| Abstract | The impact of body mass index (BMI) on postoperative survival in Japanese patients with pancreatic cancer is unclear. We examined the relationship between preoperative BMI and the prognosis of Japanese patients who underwent surgery for pancreatic cancer to determine whether BMI affects these patients’ prognosis. Of the patients who underwent pancreatectomy between January 2004 and August 2015 at our institution, 246 were pathologically diagnosed with pancreatic tubular adenocarcinoma; the cancer was located in the pancreatic head (n=161) and in the body and tail (n=85). We classified the patients by BMI: underweight (n=22), normal weight (n=190), and overweight/obese (n=34) groups. We retrospectively analyzed medical records for patient characteristics, lesion location, disease stage, postoperative complications, chemotherapy, and prognosis. Lesion location, disease stage, postoperative complications, and chemotherapy were not significantly different among the BMI groups. The median survival times were as follows (days): all patients, 686; underweight, 485; normal weight, 694; and overweight/obese, 839. In a multivariate analysis, after adjusting for competing risk factors, low BMI was associated with an increased risk of death (normal weight: HR 0.58, p=0.038; overweight/obese: HR 0.54, p=0.059). High BMI was not found to be a postoperative factor for poor prognosis in Japanese pancreatic cancer patients. |
| Keywords | pancreatic cancer BMI prognosis surgery risk factor |
| Amo Type | Original Article |
| Publication Title | Acta Medica Okayama |
| Published Date | 2018-04 |
| Volume | volume72 |
| Issue | issue2 |
| Publisher | Okayama University Medical School |
| Start Page | 129 |
| End Page | 135 |
| ISSN | 0386-300X |
| NCID | AA00508441 |
| Content Type | Journal Article |
| language | English |
| Copyright Holders | CopyrightⒸ 2018 by Okayama University Medical School |
| File Version | publisher |
| Refereed | True |
| PubMed ID | 29674761 |
| JaLCDOI | 10.18926/AMO/55852 |
|---|---|
| FullText URL | 72_2_121.pdf |
| Author | Ochiai, Hirotaka| Shirasawa, Takako| Nanri, Hinako| Nishimura, Rimei| Hoshino, Hiromi| Kokaze, Akatsuki| |
| Abstract | Several cross-sectional studies have shown that eating quickly is associated with overweight in children and adolescents. However, few cohort studies have examined this relationship. Here we investigated the relationship between eating quickly and overweight in a cohort study of fourth-grade schoolchildren (aged 9 or 10 years) who attended elementary schools in Ina-town, Japan. The children were followed for 3 years from 2001-2004 (at baseline) to 2004-2007. A questionnaire survey including information about eating speed (fast, medium, or slow) was administered, and height and weight measurements were obtained at baseline and follow-up. Overweight was defined according to the body mass index cutoff points proposed by the International Obesity Task Force. We used a Poisson regression model to examine the association between eating quickly at baseline and being overweight 3 years later. Data from 934 non-overweight children (465 boys, 469 girls) were analyzed. Eating quickly was not significantly associated with being overweight in the boys, whereas it was significantly associated with being overweight in the girls. Our analysis indicates that among girls, eating quickly leads to overweight, and that the modification of eating quickly could help prevent overweight in adolescents. |
| Keywords | eating quickly overweight schoolchildren cohort study |
| Amo Type | Original Article |
| Publication Title | Acta Medica Okayama |
| Published Date | 2018-04 |
| Volume | volume72 |
| Issue | issue2 |
| Publisher | Okayama University Medical School |
| Start Page | 121 |
| End Page | 128 |
| ISSN | 0386-300X |
| NCID | AA00508441 |
| Content Type | Journal Article |
| language | English |
| Copyright Holders | CopyrightⒸ 2018 by Okayama University Medical School |
| File Version | publisher |
| Refereed | True |
| PubMed ID | 29674760 |
| JaLCDOI | 10.18926/AMO/55851 |
|---|---|
| FullText URL | 72_2_115.pdf |
| Author | Miyagi, Yasunari| Tada, Katsuhiko| Takayoshi, Riko| Oguni, Nobutsugu| Sato, Yasushi| Shibata, Maki| Kiyokawa, Machiko| Hashimoto, Tadashi| Takada, Tomoyoshi| Oda, Takashi| Miyake, Takahito| |
| Abstract | We devised biomathematics-based formulae to estimate the standard values of fetal growth of Japanese after 22 weeks' gestation. The growth rates of bi-parietal diameter (BPD), abdominal circumference (AC), femur length (FL), and estimated fetal body weight (EFBW) at the time of gestation were assumed to be proportional to the product of the value at the time and the rest value of an unknown maximum value, respectively. The EFBW was also assumed to follow a multiple logistic function of BPD, AC and FL to fit the standard values of Japanese fetuses published by the Japan Society of Ultrasonics in Medicine. The Mann-Whitney test was used for statistical analysis. The values as a function of gestational day, t, were as follows: BPD(t)=99.6/(1+exp (2.725−0.01837＊t)) (mm); AC(t)=39.7/(1+exp (2.454−0.01379＊t)) (cm); FL(t)=79.6/(1+exp (2.851−0.01710＊t)) (mm); EFBW(t)=8045.1/(1+exp (6.028−0.06582＊BPD(t)−0.1469＊AC(t)+ 0.07377＊FL(t))) (g). EFBW as a function of BPD, AC and FL was as follows: EFBW=8045.1/(1+exp (4.747+ 0.02584＊BPD+0.1010＊AC−0.1416＊FL)) (g). When the BPD, AC and FL were at −2 standard deviation (SD), −1SD, mean and + 2SD, the EFBW values calculated by the formula were statistically closer to the standard values than conventional formulas with p-values of 4.871×10−7, 4.228×10−7, 9.777×10−7 and 0.028, respectively. The formulae based on biomathematics might be useful to estimate the fetal growth standard values. |
| Keywords | fetal growth formulae biomathematics Japanese ultrasound |
| Amo Type | Original Article |
| Publication Title | Acta Medica Okayama |
| Published Date | 2018-04 |
| Volume | volume72 |
| Issue | issue2 |
| Publisher | Okayama University Medical School |
| Start Page | 115 |
| End Page | 119 |
| ISSN | 0386-300X |
| NCID | AA00508441 |
| Content Type | Journal Article |
| language | English |
| Copyright Holders | CopyrightⒸ 2018 by Okayama University Medical School |
| File Version | publisher |
| Refereed | True |
| PubMed ID | 29674759 |
| JaLCDOI | 10.18926/AMO/55850 |
|---|---|
| FullText URL | 72_2_105.pdf |
| Author | Kato, Ryo| Iwamuro, Masaya| Hiraoka, Sakiko| Takashima, Shiho| Inokuchi, Toshihiro| Takahara, Masahiro| Kondo, Yoshitaka| Tanaka, Takehiro| Okada, Hiroyuki| |
| Abstract | To analyze the clinical characteristics of patients with ulcerative colitis who have upper gastrointestinal lesions, we retrospectively reviewed the data of 216 patients with ulcerative colitis who underwent esophagogastroduodenoscopy at our institute in April 2008-March 2016. We investigated the endoscopic features and compared the clinical characteristics between the patients with and without upper gastrointestinal lesions. Forty-two patients (19.4%) had upper gastrointestinal lesions, including multiple erosions (n=18), bamboo joint-like appearance (n=17), mucosa with white spots (n=4), friable mucosa (n=2), ulcer (n=1), and purulent deposits within the mucosa (n=1) in the stomach and/or duodenum. Compared to the patients without upper gastrointestinal lesions, those with upper gastrointestinal lesions showed significantly more frequent extraintestinal manifestations (19.0% vs. 8.0%, p<0.05) and a significant history of colectomy (33.3% vs. 12.1%, p<0.01). There were no significant differences with regard to the sex ratio, age at esophagogastroduodenoscopy, gastrointestinal symptoms, time since the diagnosis of ulcerative colitis, type of colitis at the initial diagnosis of ulcerative colitis, or gastric atrophy between the groups. In conclusion, gastroduodenal lesions were identified in 19.4% of the patients with ulcerative colitis. Esophagogastroduodenoscopy is particularly recommended for ulcerative colitis patients who show extraintestinal manifestations and for those who have undergone a colectomy. |
| Keywords | ulcerative colitis esophagogastroduodenoscopy gastritis |
| Amo Type | Original Article |
| Publication Title | Acta Medica Okayama |
| Published Date | 2018-04 |
| Volume | volume72 |
| Issue | issue2 |
| Publisher | Okayama University Medical School |
| Start Page | 105 |
| End Page | 113 |
| ISSN | 0386-300X |
| NCID | AA00508441 |
| Content Type | Journal Article |
| language | English |
| Copyright Holders | CopyrightⒸ 2018 by Okayama University Medical School |
| File Version | publisher |
| Refereed | True |
| PubMed ID | 29674758 |
| JaLCDOI | 10.18926/AMO/55849 |
|---|---|
| FullText URL | 72_2_99.pdf |
| Author | Sugihara, Yuusaku| Harada, Keita| Kato, Ryo| Yamauchi, Kenji| Takashima, Shiho| Takei, Daisuke| Yamasaki, Yasushi| Inokuchi, Toshihiro| Takahara, Masahiro| Hiraoka, Sakiko| Okada, Hiroyuki| |
| Abstract | Peroral endoscopic myotomy (POEM) for treatment of esophageal motility disorders has recently been reported to be highly effective and less invasive than other treatment. POEM was recently introduced in Okayama University Hospital under the supervision of a physician from a high-volume center. To verify the safety and efficacy of POEM during its introduction in our institution. We examined 10 cases in whom POEM was performed between January 2016 and April 2017. The patients included 7 men and 3 women, with a median age (range) of 49 years (17-74) and median symptom duration of 6 years (1-21). Seven patients had a straight esophagus, and the remaining 3 had a sigmoid esophagus. According to the Chicago classification, 6 patients were diagnosed with type I achalasia, 2 with type II achalasia, and 2 with distal esophagus spasm. Treatment outcomes and adverse events were evaluated. Treatment success was defined as a > 3 decrease in Eckardt score or a score of <3 at the time of discharge. The treatment success rate was 90%, with the average Eckardt score decreasing significantly, from 4.7 to 0.9 (p<0.05). No mucosal perforation, severe infection, mediastinitis, severe bleeding, or gastroesophageal reflux occurred intraoperatively or postoperatively. POEM was introduced to Okayama University Hospital, and the first 10 cases were accomplished safely and effectively under the supervision of an expert physician from a high-volume center. |
| Keywords | achalasia Eckardt score peroral endoscopic myotomy (POEM) |
| Amo Type | Original Article |
| Publication Title | Acta Medica Okayama |
| Published Date | 2018-04 |
| Volume | volume72 |
| Issue | issue2 |
| Publisher | Okayama University Medical School |
| Start Page | 99 |
| End Page | 104 |
| ISSN | 0386-300X |
| NCID | AA00508441 |
| Content Type | Journal Article |
| language | English |
| Copyright Holders | CopyrightⒸ 2018 by Okayama University Medical School |
| File Version | publisher |
| Refereed | True |
| PubMed ID | 29674757 |
| JaLCDOI | 10.18926/AMO/55671 |
|---|---|
| FullText URL | 72_1_95.pdf |
| Author | Kikuchi, Satoru| Kuroda, Shinji| Nishizaki, Masahiko| Matsusaki, Takashi| Mitsuhashi, Toshiharu| Kuwada, Kazuya| Kagawa, Shunsuke| Morimatsu, Hiroshi| Fujiwara, Toshiyoshi| |
| Abstract | Although epidural analgesia (EDA) is considered standard postoperative analgesia for open gastrectomy, it has been unclear whether EDA has benefits in laparoscopic gastrectomy (LG) because postoperative pain after a laparoscopic procedure is significantly reduced. We are conducting a two-arm, single-center, prospective randomized non-inferiority trial to evaluate the postoperative pain relief of patient-controlled intravenous analgesia (PCIA) compared to EDA. A total of 132 patients undergoing LG will be randomized to EDA and PCIA groups (n=64 each) for postoperative pain control. The primary endpoint is postoperative pain at 24 h after surgery. This study will clarify the optimal pain management after LG. |
| Keywords | laparoscopic gastrectomy epidural analgesia patient-controlled intravenous analgesia pain relief |
| Amo Type | Clinical Study Protocol |
| Publication Title | Acta Medica Okayama |
| Published Date | 2018-02 |
| Volume | volume72 |
| Issue | issue1 |
| Publisher | Okayama University Medical School |
| Start Page | 95 |
| End Page | 98 |
| ISSN | 0386-300X |
| NCID | AA00508441 |
| Content Type | Journal Article |
| language | English |
| Copyright Holders | CopyrightⒸ 2018 by Okayama University Medical School |
| File Version | publisher |
| Refereed | True |
| PubMed ID | 29463947 |
| JaLCDOI | 10.18926/AMO/55670 |
|---|---|
| FullText URL | 72_1_89.pdf |
| Author | Yamamoto, Norio| Miki, Takaaki| Nishiyama, Akihiro| Dan’ura, Tomoyuki| Matsui, Yuzuru| Ozaki, Toshifumi| |
| Abstract | This is the first report of extensive bilateral patellar tendon ossification occurring over a prolonged time after a unilateral knee injury. An 84-year-old Japanese man with a spinal cord injury caused by a burst fracture of the T12 vertebra presented with a bony hard prominence on the left knee, which was injured in a traffic accident when he was 77 years old. Radiography revealed extensive ossification of the bilateral patellar tendons. We review the English literature with a focus on the localization of bilateral heterotopic ossification of the knee in patients who had a central nervous system injury. |
| Keywords | heterotopic ossification patellar tendon spinal cord injury bilateral knee injury |
| Amo Type | Case Report |
| Publication Title | Acta Medica Okayama |
| Published Date | 2018-02 |
| Volume | volume72 |
| Issue | issue1 |
| Publisher | Okayama University Medical School |
| Start Page | 89 |
| End Page | 93 |
| ISSN | 0386-300X |
| NCID | AA00508441 |
| Content Type | Journal Article |
| language | English |
| Copyright Holders | CopyrightⒸ 2018 by Okayama University Medical School |
| File Version | publisher |
| Refereed | True |
| PubMed ID | 29463946 |
| JaLCDOI | 10.18926/AMO/55669 |
|---|---|
| FullText URL | 72_1_85.pdf |
| Author | Kosaki, Yoshinori| Yumoto, Tetsuya| Naito, Hiromichi| Tsuboi, Nobushige| Kameda, Masahiro| Hirano, Masayuki| Morizane, Yuki| Senoo, Takaya| Tokuyama, Eijirou| Nakao, Atsunori| |
| Abstract | Traumatic eyeball luxation is a rare clinical condition with a dramatic presentation. Here, we describe a unique case of traumatic globe luxation and complete optic nerve transection caused by heavy object compression. A 45-year-old male automobile mechanic was injured when a truck slipped from its supports, crushing his head and face. On arrival, his right eyeball was obviously displaced anteriorly and he had no light perception. Computed tomography revealed complex frontal bone and facial fractures with underlying brain contusion in addition to complete transection of the right optic nerve. The patient was successfully treated using a multidisciplinary approach. |
| Keywords | globe luxation optic nerve avulsion traumatic brain injury facial trauma |
| Amo Type | Case Report |
| Publication Title | Acta Medica Okayama |
| Published Date | 2018-02 |
| Volume | volume72 |
| Issue | issue1 |
| Publisher | Okayama University Medical School |
| Start Page | 85 |
| End Page | 88 |
| ISSN | 0386-300X |
| NCID | AA00508441 |
| Content Type | Journal Article |
| language | English |
| Copyright Holders | CopyrightⒸ 2018 by Okayama University Medical School |
| File Version | publisher |
| Refereed | True |
| PubMed ID | 29463945 |
| JaLCDOI | 10.18926/AMO/55668 |
|---|---|
| FullText URL | 72_1_81.pdf |
| Author | Otani, Hiroki| Makihara, Shigeki| |
| Abstract | Internal hernia related to paracecal hernia is a rare disease and is difficult to confirm by preoperative diagnosis. We recently encountered a case of an 83-year-old woman who had lower abdominal pain in her right quadrant. Based on physical findings and CT findings she was diagnosed as having small bowel obstruction by internal hernia around the cecum. She underwent emergency operation with laparoscopic surgery and was diagnosed with a paracecal hernia and treated laparoscopically. After we dissected the ventral wall of the hernia sac and enlarged the hernia orifice, we reduced the trapped small intestine into the abdominal space. We determined that the herniated portion of the small intestine was not necrotic and therefore did not resect it. Although paracecal hernia is a rare internal hernia, physicians should be aware of it as a differential diagnosis for small bowel obstruction because of its rapid progression to strangulation and necrosis. We highlight the importance of recognizing CT findings of paracecal internal hernia. Laparoscopy was effective both for making a definitive diagnosis and treating paracecal hernia with relatively little invasion. |
| Keywords | paracecal hernia laparoscopic surgery internal hernia small bowel obstruction |
| Amo Type | Case Report |
| Publication Title | Acta Medica Okayama |
| Published Date | 2018-02 |
| Volume | volume72 |
| Issue | issue1 |
| Publisher | Okayama University Medical School |
| Start Page | 81 |
| End Page | 84 |
| ISSN | 0386-300X |
| NCID | AA00508441 |
| Content Type | Journal Article |
| language | English |
| Copyright Holders | CopyrightⒸ 2018 by Okayama University Medical School |
| File Version | publisher |
| Refereed | True |
| PubMed ID | 29463944 |
