result 3160 件
| FullText URL | fulltext20220413-8.pdf figure20220413-8.pdf |
|---|---|
| Author | Bian, Zhihong| Liu, Xia| Feng, Tian| Yu, Haibo| Hu, Xiao| Hu, Xinran| Bian, Yuting| Sun, Hongming| Tadokoro, Koh| Takemoto, Mami| Yunoki, Taijun| Nakano, Yumiko| Fukui, Yusuke| Morihara, Ryuta| Abe, Koji| Yamashita, Toru| |
| Keywords | Alzheimer’s disease cerebral amyloid angiopathy chronic cerebral hypoperfusion rivaroxaban warfarin |
| Note | This is an Accepted Manuscript of an article published by IOS Press. available online: https://doi.org/10.3233/jad-215318| |
| Published Date | 2022-3-8 |
| Publication Title | Journal of Alzheimer's Disease |
| Volume | volume86 |
| Issue | issue1 |
| Publisher | IOS Press |
| Start Page | 111 |
| End Page | 123 |
| ISSN | 1387-2877 |
| NCID | AA11545428 |
| Content Type | Journal Article |
| language | English |
| OAI-PMH Set | 岡山大学 |
| Copyright Holders | Copyright ©2022 IOS Press All rights reserved. |
| File Version | author |
| PubMed ID | 35001892 |
| DOI | 10.3233/jad-215318 |
| Web of Science KeyUT | 000768536700003 |
| Related Url | isVersionOf https://doi.org/10.3233/jad-215318 |
| FullText URL | fulltext20220413-7.pdf |
|---|---|
| Author | Mifune, Tomoyo| Tanabe, Katsuyuki| Nakashima, Yuri| Tanimura, Satoshi| Sugiyama, Hitoshi| Sato, Yasufumi| Wada, Jun| |
| Keywords | Vasohibin-1 Microtubules Detyrosination Podocytes |
| Note | © 2022 Elsevier Inc. This manuscript version is made available under the CC-BY-NC-ND 4.0 License. http://creativecommons.org/licenses/by-nc-nd/4.0/. This is the accepted manuscript version. The formal published version is available at [https://doi.org/10.1016/j.bbrc.2022.02.047] . | |
| Published Date | 2022-4 |
| Publication Title | Biochemical and Biophysical Research Communications |
| Volume | volume599 |
| Publisher | Elsevier BV |
| Start Page | 93 |
| End Page | 99 |
| ISSN | 0006-291X |
| Content Type | Journal Article |
| language | English |
| OAI-PMH Set | 岡山大学 |
| Copyright Holders | © 2022 Elsevier Inc. |
| File Version | author |
| PubMed ID | 35180473 |
| DOI | 10.1016/j.bbrc.2022.02.047 |
| Web of Science KeyUT | 000759467800001 |
| Related Url | isVersionOf https://doi.org/10.1016/j.bbrc.2022.02.047 |
| FullText URL | fulltext20220413-5.pdf |
|---|---|
| Author | Tanabe, Ryo| Hongo, Takashi| Mandai, Yasuhiro| Inaba, Mototaka| Yorifuji, Takashi| Nakao, Atsunori| Elmer, Jonathan| Naito, Hiromichi| |
| Keywords | DNAR EMT OHCA Stress |
| Published Date | 2022-03-03 |
| Publication Title | Resuscitation |
| Volume | volume173 |
| Publisher | Elsevier BV |
| Start Page | 61 |
| End Page | 68 |
| ISSN | 0300-9572 |
| Content Type | Journal Article |
| language | English |
| OAI-PMH Set | 岡山大学 |
| Copyright Holders | © 2022 The Author(s) |
| File Version | publisher |
| PubMed ID | 35143903 |
| DOI | 10.1016/j.resuscitation.2022.01.028 |
| Web of Science KeyUT | 000767483800011 |
| Related Url | isVersionOf https://doi.org/10.1016/j.resuscitation.2022.01.028 |
| FullText URL | fulltext20220413-4.pdf |
|---|---|
| Author | Takamura, Yuta| Morishita, Ken-ichi| Kikuzawa, Shota| Watanabe, Masaki| Kakuta, Hiroki| |
| Published Date | 2022-02-01 |
| Publication Title | Chemical and Pharmaceutical Bulletin |
| Volume | volume70 |
| Issue | issue2 |
| Publisher | Pharmaceutical Society of Japan |
| Start Page | 146 |
| End Page | 154 |
| ISSN | 0009-2363 |
| NCID | AA00602100 |
| Content Type | Journal Article |
| language | English |
| OAI-PMH Set | 岡山大学 |
| Copyright Holders | © 2022 The Pharmaceutical Society of Japan |
| File Version | publisher |
| PubMed ID | 35110435 |
| DOI | 10.1248/cpb.c21-00911 |
| Web of Science KeyUT | 000759334500007 |
| Related Url | isVersionOf https://doi.org/10.1248/cpb.c21-00911 |
| JaLCDOI | 10.18926/63356 |
|---|---|
| FullText URL | biess_6_166_174.pdf |
| Author | Kim, Dong Kwang| Leihy, Peodair| Teo, Ian| Freeman, Brigid| |
| Abstract | Japan's National Universities are now subject to "corporate" structures that, by recognizing the universities as legal persons and not simply parts of the state apparatus, aim to more closely follow models in many Western countries. The COVID-19 pandemic has disrupted their development of more proactive institutional plans and indeed institutional identities. This study traces and explains vocabulary associated with current challenges for universities around the world, and argues that the broad concept of sustainability is a central theme around which a university may build and sustain an enduring self-image. |
| Keywords | post-coronial post-colonial Japanese National Universities corporatization identity sustainability |
| Publication Title | Bulletin of Institute for Education and Student Services, Okayama University |
| Published Date | 2021-12-30 |
| Volume | volume6 |
| Start Page | 166 |
| End Page | 174 |
| ISSN | 2432-9665 |
| language | English |
| File Version | publisher |
| JaLCDOI | 10.18926/63338 |
|---|---|
| FullText URL | biess_6_148_165.pdf |
| Author | Kiwa, Toshihiko| Yokoya, Takayoshi| Chenevier, Bernard| Cosmo, Valeria Di | Truccato, Marco| Sacks, William| Sauerwein, Wolfgang| |
| Abstract | Based on a statistical analysis of R&D activities in the field of superconductivity (SC) in a broad sense, the paper reports that Japan's leadership is strong over the past 20 years, in terms of researchers publications and patents. It also essentially shows that among the main world players, the Japanese normalized contribution is significantly dominating, although some trend towards a diminished leadership is observed in the data over the period 2005 -present time. Finally, the paper highlights that by taking advantage of their internationally recognized expertise in the field, joint Japanese and European research teams may advance superconductivity as a reliable road to meet Energy and Health SDGs (Sustainable Development Goals -UNESCO 2015). |
| Keywords | Statistical review of superconductivity-related achievements energy health Okayama University and SDGs joint Japanese and European leadership in superconductivity |
| Publication Title | Bulletin of Institute for Education and Student Services, Okayama University |
| Published Date | 2021-12-30 |
| Volume | volume6 |
| Start Page | 148 |
| End Page | 165 |
| ISSN | 2432-9665 |
| language | English |
| File Version | publisher |
| JaLCDOI | 10.18926/CTED/63310 |
|---|---|
| Title Alternative | An Examination of the Teachers’ Cognitive Dimensions for Teacher-Student Relationships -Through a Case Study of Three Junior High School Teachers- |
| FullText URL | cted_012_227.pdf |
| Author | Iida, Miyako| |
| Abstract | 教師の認知次元が，生徒との関係性や生徒の学級適応感にどのように影響しているのか，各認知次元ごとにその意味合いを確認することを目的とし，３学級の生徒と担任教師を対象として検討を行った。すべての認知次元が生徒の学級適応感や生徒との関係性に対し等しく影響力を持つわけではなく，特定の認知次元がキーとなっていることが示された。また，先行研究から示されているように，生徒認知次元の数が少ないと，１つの次元にいくつもの意味合いや働きが凝縮されるのに対し，３つ以上の認知次元を持つ場合には，各次元の役割は分化し，評価的意味合いを帯びない中立的で特徴記述的な次元も生まれることが確認された。中学校教師の生徒認知次元は小学校教師に比べ，より個性的で独自性の強い視点となっている可能性が示唆され，中学校以降の教師の生徒認知次元に関わる知見の拡大と，その実践的活用の可能性についての検討を進める必要性が示された。 |
| Keywords | 教師用RCRT(RCRT for teachers) 学級適応(school adjustment) Person-Environment fit(Person-Environment Fit) 生徒認知(perception for students) 教師-生徒関係(teacher-student relationships) |
| Publication Title | Bulletin of Center for Teacher Education and Development, Okayama University |
| Published Date | 2022-03-30 |
| Volume | volume12 |
| Start Page | 227 |
| End Page | 241 |
| ISSN | 2186-1323 |
| language | Japanese |
| Copyright Holders | Copyright © 2022 岡山大学教師教育開発センター |
| File Version | publisher |
| JaLCDOI | 10.18926/CTED/63301 |
|---|---|
| Title Alternative | The Current Status and Issues of Gender-Free Education in Japan and China: Focusing on the Analysis of School Curriculum at the Elementary and Middle School Levels |
| FullText URL | cted_012_103.pdf |
| Author | WANG, Heqiao| Hirata, Yoshitsugu| |
| Abstract | 20世紀末、人権理念の尊重や人間存在の多様性を出発点として平等な両性関係の構築や男女共同参画社会の実現を達成するべく、様々な法制度が整備されていった。だが、日本および中国において、ジェンダーにおける平等の理念が広がっているにもかかわらず、いまだ現在の学校教育にはカリキュラムにおけるジェンダーの不平等が温存されている可能性がある。本研究は、日中の小中学校のカリキュラムにおけるジェンダーフリーに関わる教育内容を考察対象とする。各国の小中段階における学校教育のカリキュラムとして日本の学習指導要領、中国の課程標準を取り上げ、ジェンダーフリーの視点から分析を加える。そして、日本と中国の小中段階のカリキュラムにおけるジェンダーフリー教育の異同点を明らかにする。 |
| Keywords | ジェンダーフリー教育 (Gender-free education) 日中比較(Japan-China comparison) カリキュラム(Curriculum) 学習指導要領(Curriculum Guideline) 課程標準(Curriculum Standard) |
| Publication Title | Bulletin of Center for Teacher Education and Development, Okayama University |
| Published Date | 2022-03-30 |
| Volume | volume12 |
| Start Page | 103 |
| End Page | 117 |
| ISSN | 2186-1323 |
| language | Japanese |
| Copyright Holders | Copyright © 2022 岡山大学教師教育開発センター |
| File Version | publisher |
| JaLCDOI | 10.18926/CTED/63298 |
|---|---|
| FullText URL | cted_012_059.pdf |
| Author | Shiota(Seiyo), Yui| Takahashi, Kei| Katayama, Mika| |
| Abstract | 本論は，幼児の描画活動におけるキャラクター表現と図形模写能力の関連性について考察する。そこで，キャラクター表現の有無が，図形模写能力に与える影響を明らかにするため，①キャラクター表現を行う幼児，②キャラクターは描かないが一般的な描画を行う幼児，③自発的に描画活動を行わない幼児，の３群に分け図形模写能力を比較検討した。その結果，キャラクター表現をする幼児も，一般的な描画をする幼児と同水準の図形模写能力を有していることが，明らかになった。このことから，キャラクター表現は，一般の描画表現と同様に，描画経験の蓄積となる表現形式の１つになり得ると考えられる。 |
| Keywords | 保育施設(preschool facility) 幼児(preschoolers) 描画活動(drawing activities) キャラクター表現(drawing characters) 図形模写能力(shapes copying ability) |
| Publication Title | Bulletin of Center for Teacher Education and Development, Okayama University |
| Published Date | 2022-03-30 |
| Volume | volume12 |
| Start Page | 59 |
| End Page | 73 |
| ISSN | 2186-1323 |
| language | Japanese |
| Copyright Holders | Copyright © 2022 岡山大学教師教育開発センター |
| File Version | publisher |
| Title Alternative | Lemierre's syndrome following peritonsillar abscess : A case report |
|---|---|
| FullText URL | fulltext20220330.pdf |
| Author | KAJIHARA, Sohei| ISHIHARA, Hisashi| KARIYA, Akifumi| AKISADA, Naoki| SHIGEHARA, Akiko| SATO, Aki| HAMADA, Koji| AKAGI, Yusuke| |
| Keywords | Lemierre's syndrome Fusobacterium necrophorum Antimicrobial Resistance 扁桃周囲膿瘍 耳鼻咽喉科救急 |
| Published Date | 2021-03-20 |
| Publication Title | Otologia Fukuoka |
| Volume | volume67 |
| Issue | issue2 |
| Publisher | 耳鼻と臨床会 |
| Start Page | 112 |
| End Page | 117 |
| ISSN | 0447-7227 |
| NCID | AN00107114 |
| Content Type | Journal Article |
| language | Japanese |
| OAI-PMH Set | 岡山大学 |
| Copyright Holders | © 2021 耳鼻と臨床会 |
| File Version | publisher |
| DOI | 10.11334/jibi.67.2_112 |
| Related Url | isVersionOf https://doi.org/10.11334/jibi.67.2_112 |
| FullText URL | fulltext20220316-1.pdf table20220316-1.pdf figure1_20220316-1.pdf figure2_20220316-1.pdf |
|---|---|
| Author | Maruyama, Takayuki| Kobayashi, Terumasa| Sugiura, Yoshio| Yoneda, Toshiki| Ekuni, Daisuke| Morita, Manabu| |
| Keywords | experimental animal model microRNA mRNA obesity periodontitis |
| Note | This is the peer reviewed version of the following article: [Maruyama, T, Kobayashi, T, Sugiura, Y, Yoneda, T, Ekuni, D, Morita, M. Association between serum miRNAs and gingival gene expression in an obese rat model. J Periodont Res. 2022; 00: 1– 8. doi:10.1111/jre.12979], which has been published in final form at https://doi.org/10.1111/jre.12979. This article may be used for non-commercial purposes in accordance with Wiley Terms and Conditions for Use of Self-Archived Versions. This article may not be enhanced, enriched or otherwise transformed into a derivative work, without express permission from Wiley or by statutory rights under applicable legislation. Copyright notices must not be removed, obscured or modified. The article must be linked to Wiley’s version of record on Wiley Online Library and any embedding, framing or otherwise making available the article or pages there of by third parties from platforms, services and websites other than Wiley Online Library must be prohibited.| This fulltext is available in Mar. 2023.| |
| Published Date | 2022-3-2 |
| Publication Title | Journal of Periodontal Research |
| Volume | volume57 |
| Issue | issue3 |
| Publisher | Wiley |
| Start Page | 502 |
| End Page | 509 |
| ISSN | 0022-3484 |
| Content Type | Journal Article |
| language | English |
| OAI-PMH Set | 岡山大学 |
| Copyright Holders | © 2022 John Wiley & Sons A/S. Published by John Wiley & Sons Ltd |
| File Version | author |
| PubMed ID | 35234284 |
| DOI | 10.1111/jre.12979 |
| Web of Science KeyUT | 000762837900001 |
| Related Url | isVersionOf https://doi.org/10.1111/jre.12979 |
| FullText URL | fulltext.pdf |
|---|---|
| Author | Tabuchi, Masako| Inoue, Katsumi| Usui-Kataoka, Hitomi| Kobayashi, Kazuko| Teramoto, Misako| Takasugi, Koji| Shikata, Kenichi| Yamamura, Masahiro| Ando, Kenji| Nishida, Keiichiro| Kasahara, Junko| Kume, Noriaki| Lopez, Luis R.| Mitsudo, Kazuaki| Nobuyoshi, Masakiyo| Yasuda, Tatsuji| Kita, Toru| Makino, Hirofumi| Matsuura, Eiji| |
| Keywords | beta 2-glycoprotein I oxidized LDL/beta 2-glycoprotein I complexes diabetes mellitus oxidized LDL |
| Published Date | 2007-04 |
| Publication Title | Journal Of Lipid Research |
| Volume | volume48 |
| Issue | issue4 |
| Publisher | ELSEVIER |
| Start Page | 768 |
| End Page | 781 |
| ISSN | 0022-2275 |
| NCID | AA00701215 |
| Content Type | Journal Article |
| language | English |
| OAI-PMH Set | 岡山大学 |
| Copyright Holders | © 2007 by the American Society for Biochemistry and Molecular Biology, Inc. |
| File Version | publisher |
| PubMed ID | 17261875 |
| DOI | 10.1194/jlr.M600414-JLR200 |
| Web of Science KeyUT | 000245627100003 |
| Related Url | isVersionOf https://doi.org/10.1194/jlr.M600414-JLR200 |
| Title Alternative | Downregulation of PAR-1 and PAR-2 by Rivaroxaban |
|---|---|
| FullText URL | fulltext20220309-4.pdf Figure20220309-4.pdf |
| Author | Morihara, Ryuta| Yamashita, Toru| Kono, Syoichiro| Shang, Jingwei| Nakano, Yumiko| Sato, Kota| Hishikawa, Nozomi| Ohta, Yasuyuki| Heitmeier, Stefan| Perzborn, Elisabeth| Abe, Koji| |
| Keywords | PAR-3 PAR-4 tissue plasminogen activator warfarin |
| Note | This is the peer reviewed version of the following article: [Morihara, R., Yamashita, T., Kono, S., Shang, J., Nakano, Y., Sato, K., Hishikawa, N., Ohta, Y., Heitmeier, S., Perzborn, E. and Abe, K. (2017), Reduction of intracerebral hemorrhage by rivaroxaban after tPA thrombolysis is associated with downregulation of PAR-1 and PAR-2. Journal of Neuroscience Research, 95: 1818-1828. https://doi.org/10.1002/jnr.24013], which has been published in final form at [https://doi.org/10.1002/jnr.24013]. This article may be used for non-commercial purposes in accordance with Wiley Terms and Conditions for Use of Self-Archived Versions. This article may not be enhanced, enriched or otherwise transformed into a derivative work, without express permission from Wiley or by statutory rights under applicable legislation. Copyright notices must not be removed, obscured or modified. The article must be linked to Wiley’s version of record on Wiley Online Library and any embedding, framing or otherwise making available the article or pages there of by third parties from platforms, services and websites other than Wiley Online Library must be prohibited.| |
| Published Date | 2016-12-30 |
| Publication Title | Journal of Neuroscience Research |
| Volume | volume95 |
| Issue | issue9 |
| Publisher | Wiley |
| Start Page | 1818 |
| End Page | 1828 |
| ISSN | 0360-4012 |
| NCID | AA00703378 |
| Content Type | Journal Article |
| language | English |
| OAI-PMH Set | 岡山大学 |
| Copyright Holders | ©2016 Wiley Periodicals, Inc. |
| File Version | author |
| DOI | 10.1002/jnr.24013 |
| Web of Science KeyUT | 000427450300275 |
| Related Url | isVersionOf https://doi.org/10.1002/jnr.24013 |
| FullText URL | fulltext20220308-2.pdf |
|---|---|
| Author | Morihara, Ryuta| Yamashita, Toru| Deguchi, Kentaro| Tsunoda, Keiichiro| Manabe, Yasuhiro| Takahashi, Yoshiaki| Yunoki, Taijun| Sato, Kota| Nakano, Yumiko| Kono, Syoichiro| Ohta, Yasuyuki| Hishikawa, Nozomi| Abe, Koji| |
| Note | Internal Medicine, 2017, 56(17), 2343-2346| |
| Published Date | 2017-09-01 |
| Publication Title | Internal Medicine |
| Volume | volume56 |
| Issue | issue17 |
| Publisher | Japanese Society of Internal Medicine |
| Start Page | 2343 |
| End Page | 2346 |
| ISSN | 0918-2918 |
| NCID | AA10827774 |
| Content Type | Journal Article |
| language | English |
| OAI-PMH Set | 岡山大学 |
| Copyright Holders | © 2017 The Japanese Society of Internal Medicine |
| File Version | publisher |
| PubMed ID | 28794365 |
| DOI | 10.2169/internalmedicine.8438-16 |
| Web of Science KeyUT | 000411760900019 |
| Related Url | isVersionOf https://doi.org/10.2169/internalmedicine.8438-16 |
| FullText URL | fulltext20220302-1.pdf |
|---|---|
| Author | Miyoshi, Shin-ichi| Okubo, Naomi| Mitsumori, Satoko| |
| Keywords | Surfactant Washing detergent Linear alkylbenzene sulfonate Soil bacteria |
| Note | This is the peer reviewed version of the following article: [Miyoshi, S, Okubo, N, Mitsumori, S. Isolation and identification of soil bacteria resistant to surfactants in washing detergents. J Surfact Deterg. 2022; 1– 5. https://doi.org/10.1002/jsde.12587], which has been published in final form at [https://doi.org/10.1002/jsde.12587]. This article may be used for non-commercial purposes in accordance with Wiley Terms and Conditions for Use of Self-Archived Versions. This article may not be enhanced, enriched or otherwise transformed into a derivative work, without express permission from Wiley or by statutory rights under applicable legislation. Copyright notices must not be removed, obscured or modified. The article must be linked to Wiley’s version of record on Wiley Online Library and any embedding, framing or otherwise making available the article or pages there of by third parties from platforms, services and websites other than Wiley Online Library must be prohibited.| |
| Published Date | 2022-02-11 |
| Publication Title | Journal of Surfactants and Detergents |
| Volume | volume25 |
| Publisher | Wiley |
| Start Page | 521 |
| End Page | 525 |
| ISSN | 1097-3958 |
| Content Type | Journal Article |
| language | English |
| OAI-PMH Set | 岡山大学 |
| Copyright Holders | © 2022 AOCS. |
| File Version | author |
| DOI | 10.1002/jsde.12587 |
| Web of Science KeyUT | 000754169600001 |
| Related Url | isVersionOf https://doi.org/10.1002/jsde.12587 |
| FullText URL | fulltext.pdf |
|---|---|
| Author | Umebayashi, Ryoko| Uchida, Haruhito Adam| Matsuoka-Uchiyama, Natsumi| Sugiyama, Hitoshi| Wada, Jun| |
| Keywords | chronic kidney disease medical checkup risk factor |
| Published Date | 2022-01-12 |
| Publication Title | Journal Of Personalized Medicine |
| Volume | volume12 |
| Issue | issue1 |
| Publisher | MDPI |
| Start Page | 97 |
| ISSN | 2075-4426 |
| Content Type | Journal Article |
| language | English |
| OAI-PMH Set | 岡山大学 |
| Copyright Holders | © 2022 by the authors. |
| File Version | publisher |
| PubMed ID | 35055412 |
| DOI | 10.3390/jpm12010097 |
| Web of Science KeyUT | 000757349900001 |
| Related Url | isVersionOf https://doi.org/10.3390/jpm12010097 |
| JaLCDOI | 10.18926/AMO/63216 |
|---|---|
| FullText URL | 76_1_85.pdf |
| Author | Omi, Hirotsugu| Tomita, Takashi| Ichinohe, Masayuki| Harada, Yoshifumi| Sato, Hideki| Ito, Junji| |
| Abstract | A 75-year-old woman underwent L4-L5 lateral interbody fusion for L4-5 foraminal stenosis with the use of percutaneous pedicle screws. On the day after the surgery, she was in shock. Emergency contrast-enhanced CT showed active extravasation from the 4th lumbar artery with a transverse process fracture. A radiologist performed a successful transarterial embolization, and the patient then began walking training on the 4th day post-surgery. Close attention should be paid to the insertion of a percutaneous pedicle screw, as it may cause a lumbar artery injury; in such a case, transarterial embolization is the preferred treatment. |
| Keywords | lumbar artery injury percutaneous pedicle screw transverse process fracture hematoma |
| Amo Type | Case Report |
| Publication Title | Acta Medica Okayama |
| Published Date | 2022-02 |
| Volume | volume76 |
| Issue | issue1 |
| Publisher | Okayama University Medical School |
| Start Page | 85 |
| End Page | 88 |
| ISSN | 0386-300X |
| NCID | AA00508441 |
| Content Type | Journal Article |
| language | English |
| Copyright Holders | Copyright Ⓒ 2022 by Okayama University Medical School |
| File Version | publisher |
| Refereed | True |
| PubMed ID | 35237003 |
| Web of Science KeyUT | 000762803800003 |
| JaLCDOI | 10.18926/AMO/63213 |
|---|---|
| FullText URL | 76_1_63.pdf |
| Author | Zhang, Bei| Pei, Zhixin| Wang, Hongxia| Wu, Huimin| Wang, Junjie| Bai, Junjun| Song, Qinglin| |
| Abstract | We analyzed the treatment effects of chidamide and decitabine in combination with a HAG (homoharringtonine, cytarabine, G-CSF) priming regimen (CDHAG) in acute myeloid leukemia (AML) patients with TP53 mutation. Seven TP53 mutated AML patients were treated with CDHAG. The treatment effects were assessed using hemogram detection and bone marrow aspirate. The possible side effects were evaluated based on both hematological and non-hematological toxicity. Four of the seven patients were classified as having achieved complete remission after CDHAG treatment; one patient was considered to have achieved partial remission, and the remaining two patients were considered in non-remission. The overall response rate (ORR) to CDHAG was 71.4%. Regarding the side effects, the hematological toxicity level of the seven patients ranged from level III to level IV, and infections that occurred at lung, blood, and skin were recorded. Nausea, vomiting, liver injury, and kidney injury were also detected. However, all side effects were attenuated by proper management. The CDHAG regimen clearly improved the ORR (71.4%) of TP53-mutated AML patients, with no severe side effects. |
| Keywords | acute myeloid leukemia chidamide decitabine HAG TP53 mutation |
| Amo Type | Original Article |
| Publication Title | Acta Medica Okayama |
| Published Date | 2022-02 |
| Volume | volume76 |
| Issue | issue1 |
| Publisher | Okayama University Medical School |
| Start Page | 63 |
| End Page | 70 |
| ISSN | 0386-300X |
| NCID | AA00508441 |
| Content Type | Journal Article |
| language | English |
| Copyright Holders | Copyright Ⓒ 2022 by Okayama University Medical School |
| File Version | publisher |
| Refereed | True |
| PubMed ID | 35237000 |
| Web of Science KeyUT | 000762812700009 |
| JaLCDOI | 10.18926/AMO/63206 |
|---|---|
| FullText URL | 76_1_33.pdf |
| Author | Zhou, Jia-Yi| Hou, Hai-Tao| Wang, Shi-Fu| Yang, Qin| He, Guo-Wei| |
| Abstract | Trace elements selenium (Se) and cobalt (Co) are essential in the human body, and a correlation between Se and cardiac surgery has been suggested. We investigated the plasma concentrations of Se and Co during and after coronary artery bypass grafting (CABG) surgery under cardiopulmonary bypass (CPB). From December 2019 to January 2020, preoperative plasma samples from isolated first-time CABG patients (n=20; 10 males, 10 females) were prospectively collected post-anesthesia and before CPB (T1), 45 min after CPB started (T2), 90 min after CPB started (T3), and postoperative days 1 (T4), and day 4 (T5). The plasma concentrations of Se and Co were measured. The Se concentration was significantly decreased at T2 (105.24±4.08 vs. 68.56±2.42 μg/L, p<0.001) and T3 (105.24±4.08 vs. 80.41±3.40 μg/L, p<0.001). The Co concentration was significantly decreased at T4 (0.35±0.19 vs. 0.26±0.13 μg/L, p<0.01) and T5 (0.35±0.19 vs. 0.23±0.11 μg/L, p<0.001). Five patients developed atrial fibrillation (AF); there was no other operative mortality or major morbidity. This is the first report of alterations of plasma Se and Co concentrations during and after CABG surgery. Our results may indicate that Se supplementation before or during CABG and Co supplementation after CABG may become necessary for patients undergoing CABG. |
| Keywords | trace element CABG cardiopulmonary bypass selenium cobalt |
| Amo Type | Original Article |
| Publication Title | Acta Medica Okayama |
| Published Date | 2022-02 |
| Volume | volume76 |
| Issue | issue1 |
| Publisher | Okayama University Medical School |
| Start Page | 33 |
| End Page | 39 |
| ISSN | 0386-300X |
| NCID | AA00508441 |
| Content Type | Journal Article |
| language | English |
| Copyright Holders | Copyright Ⓒ 2022 by Okayama University Medical School |
| File Version | publisher |
| Refereed | True |
| PubMed ID | 35236996 |
| Web of Science KeyUT | 000762812700005 |
| FullText URL | fulltext20220216-4.pdf |
|---|---|
| Author | Nomura, Emi| Kawahara, Yuko| Omote, Yoshio| Takahashi, Yoshiaki| Matsumoto, Namiko| Ikegami, Ken| Takemoto, Mami| Hishikawa, Nozomi| Nakano, Yumiko| Yunoki, Taijun| Morihara, Ryuta| Uemura, Masahiro| Abe, Koji| Yamashita, Toru| |
| Keywords | ATP-binding cassette subfamily C member 6 (ABCC6) neurovascular diseases pseudoxanthoma elasticum (PXE) |
| Note | This is the peer reviewed version of the following article: [Nomura, E, Kawahara, Y, Omote, Y, et al. A case of a heterozygous ABCC6 mutation showing recurrent ischemic strokes and intracranial hemorrhages. Neurol Clin Neurosci. 2022; 00: 1– 4. doi:10.1111/ncn3.12575], which has been published in final form at https://doi.org/10.1111/ncn3.12575. This article may be used for non-commercial purposes in accordance with Wiley Terms and Conditions for Use of Self-Archived Versions. This article may not be enhanced, enriched or otherwise transformed into a derivative work, without express permission from Wiley or by statutory rights under applicable legislation. Copyright notices must not be removed, obscured or modified. The article must be linked to Wiley’s version of record on Wiley Online Library and any embedding, framing or otherwise making available the article or pages there of by third parties from platforms, services and websites other than Wiley Online Library must be prohibited.| |
| Published Date | 2022-2-4 |
| Publication Title | Neurology and Clinical Neuroscience |
| Volume | volume10 |
| Publisher | Wiley |
| Start Page | 98 |
| End Page | 101 |
| ISSN | 2049-4173 |
| Content Type | Journal Article |
| language | English |
| OAI-PMH Set | 岡山大学 |
| File Version | author |
| DOI | 10.1111/ncn3.12575 |
| Web of Science KeyUT | 000750987400001 |
| Related Url | isVerisonOf https://doi.org/10.1111/ncn3.12575 |
