result 18800 件
| JaLCDOI | 10.18926/AMO/49255 |
|---|---|
| FullText URL | 67_1_35.pdf |
| Author | Watanabe, Masutaka| Arita, Seizaburo| Hashizume, Hiroyuki| Honda, Mitsugi| Nishida, Keiichiro| Ozaki, Toshifumi| |
| Abstract | The purpose of this study was to quantitatively evaluate Akahori's preoperative classification of cubital tunnel syndrome. We analyzed the results for 57 elbows that were treated by a simple decompression procedure from 1997 to 2004. The relationship between each item of Akahori's preoperative classification and clinical stage was investigated based on the parameter distribution. We evaluated Akahori's classification system using multiple regression analysis, and investigated the association between the stage and treatment results. The usefulness of the regression equation was evaluated by analysis of variance of the expected and observed scores. In the parameter distribution, each item of Akahori's classification was mostly associated with the stage, but it was difficult to judge the severity of palsy. In the mathematical evaluation, the most effective item in determining the stage was sensory conduction velocity. It was demonstrated that the established regression equation was highly reliable (R＝0.922). Akahori's preoperative classification can also be used in postoperative classification, and this classification was correlated with postoperative prognosis. Our results indicate that Akahori's preoperative classification is a suitable system. It is reliable, reproducible and well-correlated with the postoperative prognosis. In addition, the established prediction formula is useful to reduce the diagnostic complexity of Akahori's classification. |
| Keywords | cubital tunnel syndrome ulnar nerve Akahoriʼs classification multiple regression analysis |
| Amo Type | Original Article |
| Publication Title | Acta Medica Okayama |
| Published Date | 2013-02 |
| Volume | volume67 |
| Issue | issue1 |
| Publisher | Okayama University Medical School |
| Start Page | 35 |
| End Page | 44 |
| ISSN | 0386-300X |
| NCID | AA00508441 |
| Content Type | Journal Article |
| language | English |
| Copyright Holders | CopyrightⒸ 2013 by Okayama University Medical School |
| File Version | publisher |
| Refereed | True |
| PubMed ID | 23439507 |
| Web of Science KeyUT | 000316829900005 |
| Related Url | http://ousar.lib.okayama-u.ac.jp/metadata/50647 |
| JaLCDOI | 10.18926/AMO/49254 |
|---|---|
| FullText URL | 67_1_25.pdf |
| Author | Ika, Katsuhiko| Suzuki, Etsuji| Mitsuhashi, Toshiharu| Takao, Soshi| Doi, Hiroyuki| |
| Abstract | The purpose of this study was to examine the association between shift work and diabetes mellitus by separating shift workers according to the intensity of their shift work (seasonal shift work and continuous shift work). Between May and October 2009, we collected data from annual health checkups and questionnaires at a manufacturing company in Shizuoka, Japan. Questionnaires were returned by 1,601 workers (response rate:96.2%, men/women＝1,314/287). Diabetes mellitus was defined as hemoglobin A1c≥6.5% and fasting blood sugar≥126mg/dl. After exclusions, which included all the women and clerical workers because they did not work in shifts, we analyzed 475 skilled male workers. After adjusting for age, smoking status, frequency of alcohol consumption, and cohabitation status, odds ratios for diabetes mellitus were 0.98 (95% confidence interval [CI]:0.28-4.81) and 2.10 (95% CI:0.77-5.71) among seasonal shift workers and continuous shift workers, respectively, compared with non-shift workers. In an age-stratified analysis (＜45 years vs.≥45 years), the association between continuous shift work and diabetes mellitus was more pronounced among older participants. Compared with non-shift workers, the risk of diabetes mellitus was increased among continuous shift workers, whereas its effect is limited among seasonal shift workers. |
| Keywords | cross-sectional study diabetes mellitus intensity Japan shift work |
| Amo Type | Original Article |
| Publication Title | Acta Medica Okayama |
| Published Date | 2013-02 |
| Volume | volume67 |
| Issue | issue1 |
| Publisher | Okayama University Medical School |
| Start Page | 25 |
| End Page | 33 |
| ISSN | 0386-300X |
| NCID | AA00508441 |
| Content Type | Journal Article |
| language | English |
| Copyright Holders | CopyrightⒸ 2013 by Okayama University Medical School |
| File Version | publisher |
| Refereed | True |
| PubMed ID | 23439506 |
| Web of Science KeyUT | 000316829900004 |
| Related Url | http://ousar.lib.okayama-u.ac.jp/metadata/50693 |
| JaLCDOI | 10.18926/AMO/49253 |
|---|---|
| FullText URL | 67_1_19.pdf |
| Author | Furukawa, Masashi| Soh, Junichi| Yamamoto, Hiromasa| Ichimura, Kouichi| Shien, Kazuhiko| Maki, Yuho| Muraoka, Takayuki| Tanaka, Norimitsu| Ueno, Tsuyoshi| Asano, Hiroaki| Tsukuda, Kazunori| Toyooka, Shinichi| Miyoshi, Shinichiro| |
| Abstract | Nuclear factor of κ-light polypeptide gene enhancer in B cells inhibitor α (NFKBIA), which is a tumor suppressor gene, was found to be silenced in lung adenocarcinomas. We examined NFKBIA expression, mutations in the EGFR and K-ras genes, and EML4-ALK fusion in 101 resected lung adenocarcinoma samples from never-smokers. NFKBIA expression was evaluated using immunohistochemistry. NFKBIA expression was negative in 16 of the 101 samples (15.8%). EGFR and K-ras mutations and EML4-ALK fusion were detected in 61 (60.5%), 1 (1.0%), and 2 (2.0%) of the 101 samples, respectively, in a completely mutually exclusive manner. Negative NFKBIA expression was observed significantly more frequently among the tumors with none of the three genetic alterations compared to those with such alterations (p＝0.009). In addition, negative NFKBIA expression was significantly more frequent among the EGFR-wild type samples compared to the EGFR-mutant samples (p＝0.013). In conclusion, NFKBIA expression was silenced in adenocarcinomas without EGFR/K-ras mutations or EML4-ALK fusion, suggesting that the silencing of NFKBIA may play an important role in the carcinogenesis of adenocarcinomas independent of EGFR/K-ras mutations or EML4-ALK fusion. |
| Keywords | never-smoker lung cancer adenocarcinoma nuclear factor of κ-light polypeptide gene enhancer in B cells inhibitor α epidermal growth factor receptor |
| Amo Type | Original Article |
| Publication Title | Acta Medica Okayama |
| Published Date | 2013-02 |
| Volume | volume67 |
| Issue | issue1 |
| Publisher | Okayama University Medical School |
| Start Page | 19 |
| End Page | 24 |
| ISSN | 0386-300X |
| NCID | AA00508441 |
| Content Type | Journal Article |
| language | English |
| Copyright Holders | CopyrightⒸ 2013 by Okayama University Medical School |
| File Version | publisher |
| Refereed | True |
| PubMed ID | 23439505 |
| Web of Science KeyUT | 000316829900003 |
| Related Url | http://ousar.lib.okayama-u.ac.jp/metadata/52534 |
| JaLCDOI | 10.18926/AMO/49252 |
|---|---|
| FullText URL | 67_1_9.pdf |
| Author | Fatmawati, Ni Nengah Dwi| Sakaguchi, Yoshihiko| Suzuki, Tomonori| Oda, Masataka| Shimizu, Kenta| Yamamoto, Yumiko| Sakurai, Jun| Matsushita, Osamu| Oguma, Keiji| |
| Abstract | Clostridium botulinum type C and D strains recently have been found to produce PLC on egg yolk agar plates. To characterize the gene, enzymatic and biological activities of C. botulinum PLCs (Cb-PLCs), the cb-plc genes from 8 strains were sequenced, and 1 representative gene was cloned and expressed as a recombinant protein. The enzymatic and hemolytic activities of the recombinant Cb-PLC were measured and compared with those of the Clostridium perfringens alpha-toxin. Each of the eight cb-plc genes encoded a 399 amino acid residue protein preceded by a 27 residue signal peptide. The protein consists of 2 domains, the N- and C-domains, and the overall amino acid sequence identity between Cb-PLC and alpha-toxin was greater than 50%, suggesting that Cb-PLC is homologous to the alpha-toxin. The key residues in the N-domain were conserved, whereas those in the C-domain which are important in membrane interaction were different than in the alpha-toxin. As expected, Cb-PLC could hydrolyze egg yolk phospholipid, p-nitrophenylphosphorylcholine, and sphingomyelin, and also exhibited hemolytic activity;however, its activities were about 4- to over 200-fold lower than those of alpha-toxin. Although Cb-PLC showed weak enzymatic and biological activities, it is speculated that Cb-PLC might play a role in the pathogenicity of botulism or for bacterial survival. |
| Keywords | botulinum phospholipase C botulinum toxin phospholipase C activity sphingomyelinase activity hemolytic activity |
| Amo Type | Original Article |
| Publication Title | Acta Medica Okayama |
| Published Date | 2013-02 |
| Volume | volume67 |
| Issue | issue1 |
| Publisher | Okayama University Medical School |
| Start Page | 9 |
| End Page | 18 |
| ISSN | 0386-300X |
| NCID | AA00508441 |
| Content Type | Journal Article |
| language | English |
| Copyright Holders | CopyrightⒸ 2013 by Okayama University Medical School |
| File Version | publisher |
| Refereed | True |
| PubMed ID | 23439504 |
| Web of Science KeyUT | 000316829900002 |
| Related Url | http://ousar.lib.okayama-u.ac.jp/metadata/49731 |
| JaLCDOI | 10.18926/AMO/49251 |
|---|---|
| FullText URL | 67_1_1.pdf |
| Author | Nishimori, Hisakazu| Maeda, Yoshinobu| Tanimoto, Mitsune| |
| Abstract | Graft-versus-host disease (GVHD) is a major complication after allogeneic hematopoietic stem cell transplantation. Chronic GVHD often presents with clinical manifestations that resemble those observed in autoimmune diseases. Standard treatment is 1-2mg/kg/day of prednisone or an equivalent dose of methylprednisolone, with continued administration of a calcineurin inhibitor for steroid sparing. However, the prognosis of steroid-refractory chronic GVHD remains poor. Classically, chronic GVHD was said to involve predominantly Th2 responses. We are now faced with a more complex picture, involving possible roles for thymic dysfunction, transforming growth factor-β (TGF-β) and platelet-derived growth factor (PDGF), B cells and autoantibodies, and Th1/Th2/Th17 cytokines, as well as regulatory T cells (Tregs), in chronic GVHD. More detailed research on the pathophysiology of chronic GVHD may facilitate the establishment of novel strategies for its prevention and treatment. |
| Keywords | chronic GVHD Th17 Am80 regulatory T cell (Treg) steroid-refractory |
| Amo Type | Review |
| Publication Title | Acta Medica Okayama |
| Published Date | 2013-02 |
| Volume | volume67 |
| Issue | issue1 |
| Publisher | Okayama University Medical School |
| Start Page | 1 |
| End Page | 8 |
| ISSN | 0386-300X |
| NCID | AA00508441 |
| Content Type | Journal Article |
| language | English |
| Copyright Holders | CopyrightⒸ 2013 by Okayama University Medical School |
| File Version | publisher |
| Refereed | True |
| PubMed ID | 23439503 |
| Web of Science KeyUT | 000316829900001 |
| JaLCDOI | 10.18926/ESR/49212 |
|---|---|
| Title Alternative | A case study on persistent appearance of the ensemble of precipitation bands in the warm sector of the Baiu front in the western Japan around 19 June 2001 |
| FullText URL | esr_019_1_039_050.pdf |
| Author | Goda, Yasuhiro| Kato, Kuranoshin| Tsukamoto, Osamu| |
| Abstract | A case study on persistent appearance of the ensemble of precipitation bands in the warm sector of the Baiu front in Kyushu District, the western part of Japan around 19 June 2001 was performed based on the operational observational data. Around 00UTC (09JST) 19 June when the Baiu front on the surface weather map was still located about a few 100kms to the north of Kyushu, the number and the total area of the meso-β or γ-scale line-shaped precipitation bands increased around Kyushu rapidly. These precipitation bands had been sustained there and gradually gathered each other to change into the Baiu frontal precipitation zone extending from the northern Kyushu to Seto-Naikai (Seto Inland Sea) around 09UTC (18JST) 19 June (the intense rainfall zone was still located in the warm sector of the Baiu front). Until ~09UTC (18JST) 19 June, the moist air flow with the latently unstable stratification had been sustained around Kyushu corresponding to the low-level southerly wind toward the surface Baiu front to the north of Kyushu. This large-scale situation would contribute greatly to the maintenance of the ensemble of the line-shaped precipitation bands in the warm sector of the Baiu front. |
| Keywords | ensemble of line-shaped precipitation bands precipitation in the warm sector of the Baiu front Baiu fronal rainfall |
| Publication Title | Okayama University Earth Science Report |
| Published Date | 2012-12-26 |
| Volume | volume19 |
| Issue | issue1 |
| Start Page | 39 |
| End Page | 50 |
| ISSN | 1340-7414 |
| language | Japanese |
| Copyright Holders | © 2012 by Okayama University Earth Science Reports Editorial Committee All Rights Reserved |
| File Version | publisher |
| NAID | 120005232330 |
| JaLCDOI | 10.18926/ESR/49210 |
|---|---|
| Title Alternative | Estimation of SPM concentration distribution over the central Seto Inland Sea |
| FullText URL | esr_019_1_019_024.pdf |
| Author | Ebi, Takahiro| Matsumoto, Hirofumi| Yamakawa, Junji| |
| Abstract | Ordinary Kriging, OK, and Regression Kriging, RK, are the spatial statistical methods that are possible to estimate a horizontal distribution in a study area from discrete data. OK is the method which takes account of only spatial auto-correlation structure of the data, while RK is the method which takes account of an interrelationship between spatial auto-correlation structure and some auxiliary variables to minimize the estimation error. Analytical processing for OK and RK methods was performed by the R-Language (R Core Team, 2012) and its some additional libraries. The auxiliary variables required to perform RK method were prepared by a GIS application, Quantum GIS (Quantum GIS Development Team, 2012). The 3-dimensional geographic representation of the estimation maps was performed by the Google Earth (Google, 2012). In this report, OK and RK methods were applied to one of the Earth scientific information, SPM (Supended Particulate Matter). Then, these methods were considered by comparing two estimation maps, and finally considered qualitatively by displaying these maps in the Google Earth. |
| Keywords | Ordinary Kriging Regression Kriging Auxiliary variable R-Language Google Earth |
| Publication Title | Okayama University Earth Science Report |
| Published Date | 2012-12-26 |
| Volume | volume19 |
| Issue | issue1 |
| Start Page | 19 |
| End Page | 24 |
| ISSN | 1340-7414 |
| language | Japanese |
| Copyright Holders | © 2012 by Okayama University Earth Science Reports Editorial Committee All Rights Reserved |
| File Version | publisher |
| NAID | 120005232328 |
| JaLCDOI | 10.18926/ESR/49209 |
|---|---|
| Title Alternative | The temperature and pressure conditions of synthetic Sibirskite and Parasibirskite |
| FullText URL | esr_019_1_013_017.pdf |
| Author | Kano, Masahiro| Yamakawa, Junji| |
| Abstract | Sibirskite (CaHBO ) and parasibirskite ₃ are in the relation of polymorphism, these are regarded as the alteration products of takedaite (Ca₃B₂O₆), occurs at Fuka mine, Okayama Prefecture. The synthesis of parasibirskite was reported by the Schäfer (1968a, b) etc. and the synthesis of sibirskite was reported by the Sun et al. (2011). To determine the formation condition of sibirskite and parasibirskite in the natural, they were synthesized from the natural takedaite (Ca₃B₂O₆). As a result, both of sibirskite and parasibirskite were formed by the duration time of 7 days with 1000 kg/cm2 and 300 oC, on the other hand, only sibirskite was formed by the duration time of 14 days with the same condition. In addition, the mixtures of sibirskite and parasibirskite were examined under the various temperatures and pressures of hydrothermal conditions. As a result, the upper limit of the stable temperature and pressure conditions of sibirskite was estimated between 350 oC and 400 oC at 1500 kg/cm2, and between 400 oC and 450 oC at 500 kg/cm2 . In the higher temperature than the condition, sibirskite were changed into shimazakiite (Ca₂B₂O₅). |
| Keywords | Sibirskite Parasibirskite Shimazakiite Fuka Hydrothermal synthesis |
| Publication Title | Okayama University Earth Science Report |
| Published Date | 2012-12-26 |
| Volume | volume19 |
| Issue | issue1 |
| Start Page | 13 |
| End Page | 17 |
| ISSN | 1340-7414 |
| language | Japanese |
| Copyright Holders | © 2012 by Okayama University Earth Science Reports Editorial Committee All Rights Reserved |
| File Version | publisher |
| NAID | 120005232327 |
| JaLCDOI | 10.18926/ESR/49208 |
|---|---|
| Title Alternative | Folded structure of the Carboniferous Ko-yama Limestone Group, Akiyoshi Belt, SW JAPAN |
| FullText URL | esr_019_1_005_011.pdf |
| Author | Inada, Noriyuki| Suzuki, Shigeyuki| Ishida, Keisuke| |
| Abstract | The fold structure of the Akiyoshi Belt was analyzed in Kawakami-cho, Okayama Prefecture, where the Lower Carboniferous to Middle Permian Ko-yama Limestone Group (Yokoyama et al., 1979), Permian Yoshii Group (Sano et al., 1987) and Triassic Nariwa Group (Teraoka, 1959) are distributed. The Nariwa Group unconformably covers the Paleozoic successions (Otoh, 1985). The Lower Carboniferous to Middle Permian Ko-yama Limestone Group, dated by foraminifers and fusulinids (Yokoyama et al., 1979), is mainly composed of massive limestone with basic volcanics, acidic tuff and chert. The Paleozoic successions of the Akiyoshi Belt were folded during the Middle to Late Permian (Suzuki et al., 1990). Strata of the Ko-yama Limestone Group generally strike E-W and dip to the north. The Hoya section about 300 m thick is composed of limestone, basic tuff, chert and acidic tuff, limestone, basic lava and tuff in ascending order. In this section, Ishida et al. (2012) recognized a nearly complete conodont faunal succession ranging from the upper Visean to the lower Moscovian. The faunal succession indicates younging southward, and the strata are overturned. A folded strucuture of tight overfold with north-dipping axial plane was reconstructed. Similar style of small scale overfolds of banded chert and turbidite were observed in the overlying Yoshii Group. |
| Keywords | folded structure Ko-yama Limestone Group Carboniferous Akiyoshi Belt |
| Publication Title | Okayama University Earth Science Report |
| Published Date | 2012-12-26 |
| Volume | volume19 |
| Issue | issue1 |
| Start Page | 5 |
| End Page | 11 |
| ISSN | 1340-7414 |
| language | Japanese |
| Copyright Holders | © 2012 by Okayama University Earth Science Reports Editorial Committee All Rights Reserved |
| File Version | publisher |
| NAID | 120005232326 |
| JaLCDOI | 10.18926/ESR/49207 |
|---|---|
| Title Alternative | Holocene environmental and sea-level changes of the Okayama Plain – evidence from peat beds – |
| FullText URL | esr_019_1_001_004.pdf |
| Author | Suzuki, Shigeyuki| |
| Abstract | Quaternary peat beds from bore-hole samples deliver information to reconstruct paleoenvironment. Altitudes of dated non-marine peat beds and marine beds allow to be created a sea-level curve. 4 peat beds (A to D) are identified from the uppermost Pleistocene to Holocene deposits of the Okayama Plain. They thought to be deposited at stable events during sea-level change. |
| Keywords | Holocene peat beds paleoenvironment sea-level change Okayama Plain |
| Publication Title | Okayama University Earth Science Report |
| Published Date | 2012-12-26 |
| Volume | volume19 |
| Issue | issue1 |
| Start Page | 1 |
| End Page | 4 |
| ISSN | 1340-7414 |
| language | Japanese |
| Copyright Holders | © 2012 by Okayama University Earth Science Reports Editorial Committee All Rights Reserved |
| File Version | publisher |
| NAID | 120005232325 |
| Author | Kato, Kuranoshin| Akagi, Rikako| Kato, Haruko| Otani, Kazuo| Nishimura, Nanako| Mitsuhata, Toshiki| Moriduka, Nozomi| Sato, Sari| |
|---|---|
| Published Date | 2012-12 |
| Publication Title | 環境制御 |
| Volume | volume34 |
| Content Type | Departmental Bulletin Paper |
| Author | Ishikawa, Teruhiko| Ishimoto, Aya| Mizushima, Shiho| |
|---|---|
| Published Date | 2012-12 |
| Publication Title | 環境制御 |
| Volume | volume34 |
| Content Type | Departmental Bulletin Paper |
| Author | Hatabu, Toshimitsu| |
|---|---|
| Published Date | 2013-02-01 |
| Publication Title | 岡山大学農学部学術報告 |
| Volume | volume102 |
| Content Type | Departmental Bulletin Paper |
| Author | Morinaga, Kunihisa| |
|---|---|
| Published Date | 2013-02-01 |
| Publication Title | 岡山大学農学部学術報告 |
| Volume | volume102 |
| Content Type | Departmental Bulletin Paper |
| Author | Kondo, Yasuhiro| |
|---|---|
| Published Date | 2013-02-01 |
| Publication Title | 岡山大学農学部学術報告 |
| Volume | volume102 |
| Content Type | Departmental Bulletin Paper |
| Author | Ishikura, Satoshi| Kajihara, Shinji| Fukushima, Keigo| Goto, Tanjuro| |
|---|---|
| Published Date | 2013-02-01 |
| Publication Title | 岡山大学農学部学術報告 |
| Volume | volume102 |
| Content Type | Departmental Bulletin Paper |
| Author | Yamaguchi, Norihito| Goto, Tanjuro| Kobiki, Kayoko| Otani, Shoko| Yoshida, Yuichi| |
|---|---|
| Published Date | 2013-02-01 |
| Publication Title | 岡山大学農学部学術報告 |
| Volume | volume102 |
| Content Type | Departmental Bulletin Paper |
| Author | Yoshida, Yuichi| Shingai, Aya| Ooyama, Mitsuo| Murakami, Kenji| Goto, Tanjuro| |
|---|---|
| Published Date | 2013-02-01 |
| Publication Title | 岡山大学農学部学術報告 |
| Volume | volume102 |
| Content Type | Departmental Bulletin Paper |
| Author | Inazumi, Daichi| Yoshida, Yuichi| Goto, Tanjuro| Murakami, Kenji| |
|---|---|
| Published Date | 2013-02-01 |
| Publication Title | 岡山大学農学部学術報告 |
| Volume | volume102 |
| Content Type | Departmental Bulletin Paper |
| Author | Yamagiwa, Yasuo| Toyoda, Kazuhiro| Inagaki, Yoshishige| Ichinose, Yuki| Hyakumachia, Mitsuro| Shiraishi, Tomonori| |
|---|---|
| Published Date | 2013-02-01 |
| Publication Title | 岡山大学農学部学術報告 |
| Volume | volume102 |
| Content Type | Departmental Bulletin Paper |
