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JaLCDOI 10.18926/AMO/57373
FullText URL 73_5_427.pdf
Author Owari, Yutaka| Suzuki, Hiromi| Miyatake, Nobuyuki|
Abstract The aim of this study was to examine in a randomized controlled trial how much the sedentary behavior (sitting time) of community-dwelling elderly Japanese subjects decreased as a result of using the “Active Guide” brochure published by the Ministry of Health, Labour and Welfare (2013) and additional documents related to the benefits of reducing sedentary behavior. A total of 86 elderly people who participated in health-club activities for one year were randomly allocated to two groups. Subjects in the intervention group received explanations of the importance of physical activity using the “Active Guide” brochure (n=42) and additional documents, while subjects in the control group did not (n=44). Physical activity was measured using a triaxial accelerometer for two weeks at baseline and again after one year. After one year of intervention, the difference in the sedentary behavior rate from baseline was −2.2% for the intervention group (n=40) and +2.5% for controls (n=40) (Welch’s t-test, p=0.007). Use of the “Active Guide” brochure and additional documents may reduce the sedentary behavior of community dwelling elderly people in Japan.
Keywords Active Guide sedentary behavior elderly people randomized controlled trial health promotion
Amo Type Original Article
Publication Title Acta Medica Okayama
Published Date 2019-10
Volume volume73
Issue issue5
Publisher Okayama University Medical School
Start Page 427
End Page 432
ISSN 0386-300X
NCID AA00508441
Content Type Journal Article
language English
Copyright Holders CopyrightⒸ 2019 by Okayama University Medical School
File Version publisher
Refereed True
PubMed ID 31649369
Web of Science KeyUT 000491886600008
JaLCDOI 10.18926/AMO/57372
FullText URL 73_5_419.pdf
Author Hishii, Shuhei| Miyatake, Nobuyuki| Nishi, Hiroyuki| Katayama, Akihiko| Ujike, Kazuhiro| Koumoto, Kiichi| Suzuki, Hiromi| Hashimoto, Hiroo|
Abstract We investigated the relationship between sedentary behavior and all-cause mortality in patients undergoing hemodialysis. A total of 71 patients (39 men, 32 women, aged 72.1±11.7 years) were enrolled in this longitudinal study. Their sedentary behavior was measured using a tri-accelerometer that provides relative values per daily wearing time. We classified the sedentary behavior time into 2 groups (under the median: short-sedentary behavior (SB) group; over the median: long-SB group) and compared the groups’ clinical parameters. We compared the groups’ survival rates by using Kaplan-Meier curves and the log-rank test, and we performed multivariate analyses by a Cox-proportional hazard model to evaluate the relationship between the sedentary behavior and the survival rate. Twenty patients (28.2%) died during the observation period. The survival rate of the short-SB group was significantly higher than that of the long-SB group. Sedentary behavior was thus an important factor for all-cause mortality even after adjusting for confounding factors by a Cox-proportional hazard model. Sedentary behavior is closely linked to all-cause mortality, especially total days and non-hemodialysis days, and reducing sedentary behavior may be beneficial to reduce the all-cause mortality of patients on chronic hemodialysis.
Keywords sedentary behavior hemodialysis mortality physical activity
Amo Type Original Article
Publication Title Acta Medica Okayama
Published Date 2019-10
Volume volume73
Issue issue5
Publisher Okayama University Medical School
Start Page 419
End Page 425
ISSN 0386-300X
NCID AA00508441
Content Type Journal Article
language English
Copyright Holders CopyrightⒸ 2019 by Okayama University Medical School
File Version publisher
Refereed True
PubMed ID 31649368
Web of Science KeyUT 000491886600007
JaLCDOI 10.18926/AMO/57371
FullText URL 73_5_413.pdf
Author Yanagihara, Yutaka| Nishida, Keigo| Watanabe, Ryuta| Koyama, Kanae| Sawada, Yuichiro| Noda, Terutaka| Asai, Seiji | Fukumoto, Tetsuya| Miura, Noriyoshi| Miyauchi, Yuki| Kikugawa, Tadahiko| Saika, Takashi|
Abstract Laparoscopic radical cystectomy (LRC) is a standard surgical treatment for muscle-invasive bladder cancer and high-risk non-muscle-invasive bladder cancer. LRC is a less invasive modality than conventional open surgery. Therefore, even elderly patients with invasive bladder cancer may be candidates for LRC. In this study, a comparative analysis of perioperative/oncological outcomes between elderly patients and younger patients who underwent LRC was performed to assess the feasibility of LRC in elderly patients. Sixty-eight consecutive patients who underwent LRC between October 2013 and March 2018 were enrolled and stratified into those younger than 75 years (n=37) and those ≥ 75 years old (n=31). The median follow-up period was 28.2 months. The preoperative and operative parameters and complications were similar in both groups. The 2-year overall survival (OS) was 64.4% in the younger vs. 76.4% in the elderly group (p=0.053), cancer-specific survival (CSS) was 79.3% vs. 81.7% (p=0.187), and recurrence-free survival (RFS) was 58.2% vs. 75.7% (p=0.174), respectively. No significant differences were observed in OS, CSS, or RFS between the groups. No significant differences were found between the groups with respect to peri-surgical/oncological outcomes. We conclude that LRC is feasible in elderly patients.
Keywords bladder cancer laparoscopic surgery radical cystectomy elderly patient
Amo Type Original Article
Publication Title Acta Medica Okayama
Published Date 2019-10
Volume volume73
Issue issue5
Publisher Okayama University Medical School
Start Page 417
End Page 418
ISSN 0386-300X
NCID AA00508441
Content Type Journal Article
language English
Copyright Holders CopyrightⒸ 2019 by Okayama University Medical School
File Version publisher
Refereed True
PubMed ID 31649367
Web of Science KeyUT 000491886600006
JaLCDOI 10.18926/AMO/57370
FullText URL 73_5_403.pdf
Author Ando, Akemi| Mitsuhashi, Toshiharu| Honda, Mitsugi| Hanayama, Yoshihisa| Hasegawa, Kou| Obika, Mikako| Kataoka, Hitomi| Otsuka, Fumio|
Abstract Osteoporosis increases the risk of bone fractures. It is diagnosed based on an individual’s bone mineral density (BMD) or a fracture without trauma. BMD is usually measured by the dual energy X-ray absorptiometry (DXA) method. Here we investigated factors for the earliest possible prediction of decreased BMD by examining the relationships between patients’ BMD values and changes in the patients’ physical and laboratory values. We retrospectively reviewed the medical records of 149 patients who visited our department in 2014-2015 for a variety of reasons and underwent an area BMD examination by DXA. We analyzed the relationships between decreasing BMD and the patients’ gender, age, body mass index (BMI), medical background, hemoglobin, electrolytes, and thyroid function. Thirty-nine of the patients were diagnosed with osteoporosis based on their T-scores. An adjusted analysis showed that female gender, aging, and increased serum calcium level were significantly related to decreasing femoral BMD, whereas high BMI was associated with an increase in femoral BMD. Collectively the results indicate that for the early detection of low BMD, it is important for general-practice physicians to consider conducting a BMD checkup when treating female and elderly patients with a low BMI and/or elevated serum calcium level.
Keywords bone mineral density (BMD) body mass index (BMI) female gender hypercalcemia osteoporosis
Amo Type Original Article
Publication Title Acta Medica Okayama
Published Date 2019-10
Volume volume73
Issue issue5
Publisher Okayama University Medical School
Start Page 403
End Page 411
ISSN 0386-300X
NCID AA00508441
Content Type Journal Article
language English
Copyright Holders CopyrightⒸ 2019 by Okayama University Medical School
File Version publisher
Refereed True
PubMed ID 31649366
Web of Science KeyUT 000491886600005
JaLCDOI 10.18926/AMO/57369
FullText URL 73_5_393.pdf
Author Yi Yi Cho Thein| Win, Myitzu| Thuzara, Moe| Matsumoto, Hiroshi| Yamada, Kiyoshi| Kimata, Yoshihiro| Leung, Michael|
Abstract Although many surgical centers perform microsurgery routinely in developed countries, performing microsurgery is challenging in resource-poor developing countries, such as Myanmar. With the establishment of educational training programs and the assistance of volunteer plastic surgical teams, local plastic surgeons can learn the techniques of microsurgery and apply them clinically. The purpose of this study was to establish baseline data and define the challenges of performing microsurgery in Yangon General Hospital, Myanmar. Sixty-four patients underwent reconstruction with free flaps from January 2015 to January 2018. All clinical records of these cases were assessed. The number of free flap reconstructions performed increased from 11 in the first year to 24 in the third year. The anterolateral thigh flap was the most commonly used (42%). The most common sites of reconstruction were mandible and intraoral defects. Total flap survival occurred in 58 of 64 patients (89%). The total salvageable flap rate for revision surgery was 66.6%; the successful revision rate was highest in 2017, with fewer complications. The flap salvage rates increased and the operative duration decreased as clinical experience improved. Establishing a microsurgical center requires a strong multidisciplinary team, clinical experience, continuous learning, sensible clinical application, and effective interdepartmental and intradepartmental cooperation.
Keywords microsurgery educational programs challenges of microsurgical free flaps reoperation flap salvageable rate
Amo Type Original Article
Publication Title Acta Medica Okayama
Published Date 2019-10
Volume volume73
Issue issue5
Publisher Okayama University Medical School
Start Page 393
End Page 401
ISSN 0386-300X
NCID AA00508441
Content Type Journal Article
language English
Copyright Holders CopyrightⒸ 2019 by Okayama University Medical School
File Version publisher
Refereed True
PubMed ID 31649365
Web of Science KeyUT 000491886600004
JaLCDOI 10.18926/AMO/57368
FullText URL 73_5_387.pdf
Author Inoue, Miyabi| Yokoyama, Teruhiko|
Abstract To assess the efficacy and safety of 2 drugs for overactive bladder (OAB), solifenacin and mirabegron. Fortyseven female OAB patients were randomized into 2 groups. Twenty-three patients were initially prescribed solifenacin for 4 weeks, followed by mirabegron for 4 weeks (group S). The other 24 patients were initially prescribed mirabegron for 4 weeks, followed by solifenacin for 4 weeks (group M). Evaluations included clinical determination of the OAB symptom score (OABSS), International Prostate Symptom Score (IPSS), and Visual Analog Scale. The IPSS significantly improved after the administration of solifenacin in both groups. The OABSS significantly improved in both groups after 4 weeks. In group M, the OABSS after eight weeks was significantly improved compared to that after 4 weeks. However, in group S, it was not significantly improved. Twelve patients experienced adverse events during the solifenacin treatment, while 2 patients experienced adverse events during the mirabegron treatment. Both solifenacin and mirabegron led to improved OAB symptoms. Switching from mirabegron to solifenacin significantly improved the OABSS. However, mirabegron led to fewer adverse events than solifenacin. We recommend that mirabegron be prescribed first for OAB patients. If patients are not satisfied with mirabegron, solifenacin should be used.
Keywords overactive bladder, randomized crossover study solifenacin mirabegron
Amo Type Original Article
Publication Title Acta Medica Okayama
Published Date 2019-10
Volume volume73
Issue issue5
Publisher Okayama University Medical School
Start Page 387
End Page 392
ISSN 0386-300X
NCID AA00508441
Content Type Journal Article
language English
Copyright Holders CopyrightⒸ 2019 by Okayama University Medical School
File Version publisher
Refereed True
PubMed ID 31649364
Web of Science KeyUT 000491886600003
JaLCDOI 10.18926/AMO/57367
FullText URL 73_5_383.pdf
Author Fu, Li| Nishibori, Masahiro|
Abstract High mobility group box-1 (HMGB1) is a non-histone, DNA-binding nuclear protein belonging to the family of damage-associated molecular patterns (DAMPs). HMGB1 has been reported to play an important role during epileptogenesis although the mechanisms of its actions are still not clear. Many hypotheses have been suggested especially about the relationship between HMGB1 and inflammation responses and blood-brain barrier disruption during epileptogenesis. In this review, we will mainly discuss the role of HMGB1 in epileptogenesis.
Keywords HMGB1 epileptogenesis inflammation blood-brain barrier
Amo Type Review
Publication Title Acta Medica Okayama
Published Date 2019-10
Volume volume73
Issue issue5
Publisher Okayama University Medical School
Start Page 383
End Page 386
ISSN 0386-300X
NCID AA00508441
Content Type Journal Article
language English
Copyright Holders CopyrightⒸ 2019 by Okayama University Medical School
File Version publisher
Refereed True
PubMed ID 31649363
Web of Science KeyUT 000491886600002
JaLCDOI 10.18926/AMO/57366
FullText URL 73_5_379.pdf
Author Wake, Hidenori|
Abstract Histidine-rich glycoprotein (HRG) is a 75 kDa glycoprotein synthesized in the liver whose plasma concentration is 100-150 μg/ml. HRG has been shown to modulate sepsis-related biological reactions by binding to several substances and cells, including heparin, factor XII, fibrinogen, thrombospondin, plasminogen, C1q, IgG, heme, LPS, dead cells, bacteria, and fungi. Therefore, reduction of plasma HRG levels in sepsis leads to dysregulation of coagulation, fibrinolysis, and immune response, resulting in disseminated intravascular coagulation and multiple organ failure. This review summarizes the binding and functional properties of HRG in sepsis.
Keywords htidine-rich glycoprotein septic pathogenesis immunothrombosis
Amo Type Review
Publication Title Acta Medica Okayama
Published Date 2019-10
Volume volume73
Issue issue5
Publisher Okayama University Medical School
Start Page 379
End Page 382
ISSN 0386-300X
NCID AA00508441
Content Type Journal Article
language English
Copyright Holders CopyrightⒸ 2019 by Okayama University Medical School
File Version publisher
Refereed True
PubMed ID 31649362
Web of Science KeyUT 000491886600001
FullText URL BE30_6_1522.pdf
Author Matsumura, Kentarou| Archer, C Ruth| Hosken, David J| Miyatake, Takahisa|
Keywords leg length mate searching morphology sperm competition, trade-off Tribolium castaneum walking
Note This fulltext will be available in Sep 2020
|
Published Date 2019-07-05
Publication Title Behavioral Ecology
Volume volume30
Issue issue6
Publisher Oxford University Press
Start Page 1522
End Page 1529
ISSN 00018244
NCID AA00558621
Content Type Journal Article
language English
OAI-PMH Set 岡山大学
File Version author
DOI 10.1093/beheco/arz110
Web of Science KeyUT 000501728400002
Related Url isVersionOf https://doi.org/10.1093/beheco/arz110
FullText URL Behav_Genet_49_5_478.pdf
Author Miyatake, Takahisa| Matsumura, Kentarou| Kitayama, Ryota| Otsuki, Keiichi| Ji, Yuhao| Fujisawa, Ryusuke| Nagaya, Naohisa|
Keywords Beetle Crossing experiment Death feigning Selection experiment Thanatosis Tribolium
Note This is an article published by Springer Nature|
Published Date 2019-06-21
Publication Title Behavior Genetics
Volume volume49
Issue issue5
Publisher Kluwer Academic/Plenum
Start Page 478
End Page 483
ISSN 00018244
NCID AA00558621
Content Type Journal Article
language English
OAI-PMH Set 岡山大学
File Version author
PubMed ID 31227945
DOI 10.1007/s10519-019-09962-x
Related Url isVersionOf https://doi.org/10.1007/s10519-019-09962-x
FullText URL ApplEntomolZool_2019_00643.pdf
Author Terada, Kenji| Matsumura, Kentarou| Miyatake, Takahisa|
Keywords Temperature Experimental evolution Hatching rate Seed beetle Callosobruchus chinensis
Note This is an Accepted Manuscript of an article published by Springer Japan|
Published Date 2019-09-13
Publication Title Applied Entomology and Zoology
Volume volume54
Publisher Springer Japan
Start Page 459
End Page 464
ISSN 00036862
NCID AA00543238
Content Type Journal Article
language English
OAI-PMH Set 岡山大学
File Version author
DOI 10.1007/s13355-019-00643-z
NAID 40022061862
Web of Science KeyUT 000503219100014
Related Url isVersionOf https://doi.org/10.1007/s13355-019-00643-z
FullText URL J_ChemPhys_150_041102_a.pdf J_ChemPhys_150_041102_p.pdf
Author Matsui, Takahiro| Yagasaki, Takuma| Matsumoto, Masakazu| Tanaka, Hideki|
Published Date 2019-01-23
Publication Title Journal of Chemical Physics
Volume volume150
Issue issue4
Publisher American Institute of Physics
Start Page 041102
ISSN 00219606
NCID AA00694991
Content Type Journal Article
language English
OAI-PMH Set 岡山大学
Copyright Holders Copyright (2019) Author(s).
File Version author
PubMed ID 30709248
DOI 10.1063/1.5083021
Related Url isVersionOf https://doi.org/10.1063/1.5083021
FullText URL J_ChemPhys_151_214506_a.pdf J_ChemPhys_151_214506_p.pdf
Author Yagasaki, Takuma| Matsumoto, Masakazu| Tanaka, Hideki|
Published Date 2019-06-06
Publication Title Journal of Chemical Physics
Volume volume150
Issue issue21
Publisher American Institute of Physics
Start Page 214506
ISSN 00219606
NCID AA00694991
Content Type Journal Article
language English
OAI-PMH Set 岡山大学
Copyright Holders Copyright (2019) Author(s).
File Version author
PubMed ID 31176337
DOI 10.1063/1.5096429
Related Url isVersionOf https://doi.org/10.1063/1.5096429
FullText URL J_ChemPhys_151_064702_p.pdf
Author Yagasaki, Takuma| Yamasaki, Masaru| Matsumoto, Masakazu| Tanaka, Hideki|
Note This article may be downloaded for personal use only. Any other use requires prior permission of the author and AIP Publishing. This article appeared in Takuma Yagasaki et. al. Formation of hot ice caused by carbon nanobrushes. The Journal of Chemical Physics 151(6), 064702 (2019)(citation of published article) and may be found at https://doi.org/10.1063/1.5111843.|
Published Date 2019-08-08
Publication Title The Journal of Chemical Physics
Volume volume151
Issue issue6
Publisher American Institute of Physics
Start Page 064702
ISSN 00219606
NCID AA00694991
Content Type Journal Article
language English
OAI-PMH Set 岡山大学
Copyright Holders Copyright (2019) Author(s)
File Version publisher
DOI 10.1063/1.5111843
Related Url isVersionOf https://doi.org/10.1063/1.5111843
FullText URL SciRep_9_1_14001_p.pdf
Author Uchiyama, Hironobu| Sasaki, Ken| Hinosawa, Shogo| Tanaka, Keisuke| Matsumura, Kentarou| Yajima, Shunsuke| Miyatake, Takahisa|
Published Date 2019-09-30
Publication Title Scientific reports
Volume volume9
Issue issue1
Publisher Springer Nature
Start Page 14001
ISSN 20452322
Content Type Journal Article
language English
OAI-PMH Set 岡山大学
Copyright Holders © The Author(s) 2019
File Version publisher
PubMed ID 31570743
DOI 10.1038/s41598-019-50440-5
Web of Science KeyUT 000488223900004
Related Url isVersionOf https://doi.org/10.1038/s41598-019-50440-5
FullText URL J_Chem_Phys_150_21_214504.pdf J_Chem_Phys_150_21_214504_p.pdf
Author Matsumoto, Masakazu| Yagasaki, Takuma| Tanaka, Hideki|
Published Date 2019-06-05
Publication Title Journal of Chemical Physics
Volume volume150
Issue issue21
Publisher American Institute of Physics
Start Page 214504
ISSN 0021-9606
NCID AA00694991
Content Type Journal Article
language English
OAI-PMH Set 岡山大学
Copyright Holders Copyright 2019 Author(s).
File Version author
PubMed ID 31176318
DOI 10.1063/1.5096556
Related Url isVersionOf https://doi.org/10.1063/1.5096556
FullText URL fulltext.pdf
Author Takahashi, Yuko| Iwamoto, Takayuki| Suzuki, Yoko| Kajiwara, Yukiko| Hatono, Minami| Tsukioki, Takahiro| Kawada, Kengo| Kochi, Mariko| Ikeda, Hirokuni| Shien, Tadahiko| Taira, Naruto| Matsuoka, Junji| Doihara, Hiroyoshi| Toyooka, Shinichi|
Keywords Gene expression Hormone receptor positive Residual tumor burden Targeted therapy Triple negative
Published Date 2020-04
Publication Title Clinical Breast Cancer
Volume volume20
Issue issue2
Publisher Elsevier
Start Page 117
End Page 124
ISSN 1526-8209
NCID AA11694891
Content Type Journal Article
language English
OAI-PMH Set 岡山大学
File Version author
PubMed ID 31570267
DOI 10.1016/j.clbc.2019.07.001
Web of Science KeyUT 000529805200021
Related Url isVersionOf https://doi.org/10.1016/j.clbc.2019.07.001
FullText URL Allergol_Int_201908007.pdf
Author Matsumoto, Naomi| Yorifuji, Takashi| Nakamura, Kazue| Ikeda, Masanori| Tsukahara, Hirokazu| Doi, Hiroyuki|
Keywords Breastfeeding Cohort Colostrum Eczema Food allergy
Published Date 2019-09-17
Publication Title Allergology International
Publisher Elsevier
ISSN 13238930
NCID AA11091750
Content Type Journal Article
language English
OAI-PMH Set 岡山大学
Copyright Holders © 2019 Japanese Society of Allergology. Production and hosting by Elsevier B.V.
File Version publisher
PubMed ID 31540813
DOI 10.1016/j.alit.2019.08.007
Related Url isVersionOf https://doi.org/10.1016/j.alit.2019.08.007
FullText URL TL60_43_151189.pdf
Author Wang, Lei| Fujii, Mayu| Namba, Misa| Yamaji, Minoru| Okamoto, Hideki|
Keywords Fluorescence ESIPT Naphthalimide Ca2+ probe
Note © 2019 Elsevier Ltd. This manuscript version is made available under the CC-BY-NC-ND 4.0 License.http://creativecommons.org/licenses/by-nc-nd/4.0/.This is the accepted manuscript version. The formal published version is available at [https://doi.org/10.1016/j.tetlet.2019.151189].|
Published Date 2019-09-20
Publication Title Tetrahedron Letters
Volume volume60
Issue issue43
Publisher PERGAMON-ELSEVIER SCIENCE
Start Page 151189
ISSN 00404039
NCID AA00861801
Content Type Journal Article
language English
OAI-PMH Set 岡山大学
Copyright Holders © 2019 Elsevier Ltd.
File Version author
DOI 10.1016/j.tetlet.2019.151189
Web of Science KeyUT 000491626500018
Related Url isVersionOf https://doi.org/10.1016/j.tetlet.2019.151189
FullText URL Biomed_Pharmacother_2019109038.pdf
Author Ueno, Hiroshi| Suemitsu, Shunsuke| Murakami, Shinji| Kitamura, Naoya| Wani, Kenta| Takahashi, Yu| Matsumoto, Yosuke| Okamoto, Motoi| Ishihara, Takeshi|
Keywords Inhalation Dizocilpine MK-801 Mouse Drug Schizophrenia
Published Date 2019-09-30
Publication Title Biomedicine & Pharmacotherapy
Volume volume117
Publisher Elsevier
Start Page 109038
ISSN 07533322
NCID AA10506249
Content Type Journal Article
language English
OAI-PMH Set 岡山大学
Copyright Holders © 2019 The Authors. Published by Elsevier Masson SAS.
File Version publisher
PubMed ID 31177060
DOI 10.1016/j.biopha.2019.109038
Web of Science KeyUT 000477804500018
Related Url isVersionOf https://doi.org/10.1016/j.biopha.2019.109038