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Author Kawai, Ikuji|
Published Date 1933-08-31
Publication Title 岡山医学会雑誌
Volume volume45
Issue issue8
Content Type Journal Article
Author Sato, Yoshitoshi|
Published Date 1933-05-31
Publication Title 岡山医学会雑誌
Volume volume45
Issue issue5
Content Type Journal Article
Author Ide'i, Ichiro|
Published Date 1933-05-31
Publication Title 岡山医学会雑誌
Volume volume45
Issue issue5
Content Type Journal Article
Author Suga, Yoshitoshi|
Published Date 1933-02-28
Publication Title 岡山医学会雑誌
Volume volume45
Issue issue2
Content Type Journal Article
Author Watanabe, Masumi|
Published Date 1934-03-31
Publication Title 岡山医学会雑誌
Volume volume46
Issue issue3
Content Type Journal Article
Author Aibara, G.|
Published Date 1934-02-28
Publication Title 岡山医学会雑誌
Volume volume46
Issue issue2
Content Type Journal Article
Author Kiyotani, Hisashi|
Published Date 1935-09-30
Publication Title 岡山医学会雑誌
Volume volume47
Issue issue9
Content Type Journal Article
Author Takemoto, Iwao|
Published Date 1935-08-31
Publication Title 岡山医学会雑誌
Volume volume47
Issue issue8
Content Type Journal Article
Author Takemoto, Iwao|
Published Date 1935-07-31
Publication Title 岡山医学会雑誌
Volume volume47
Issue issue7
Content Type Journal Article
JaLCDOI 10.18926/AMO/45274
FullText URL 65_2_143.pdf
Author Kobayashi, Yasuyuki| Saika, Takashi| Manabe, Daisuke| Nasu, Yasutomo| Kumon, Hiromi|
Abstract We analyzed the prognostic factors influencing survival after surgeries for upper urinary tract urothelial carcinoma (UUT-UC) with longer follow-up periods than in previous studies. Between January 2000 and December 2004, 386 patients underwent nephroureterectomy for UUT-UC. The data for the 221 patients with UUT-UC were retrospectively reviewed. Nine variables were evaluated for association with the survival outcomes of cause-specific survival. The prognostic significance was tested univariately with the log-rank test. The simultaneous effects of multiple prognostic factors were estimated by multiple regression analysis using the Cox proportional hazards model. The median follow-up was 38.4 months. The 5-year over all survival was 62.3%. Significant prognostic factors for disease-specific survival rate on univariate analysis were pathological stage (p0.0001), tumor grade (p0.0324), and venous invasion (p0.0001). Multivariate analysis revealed that only venous invasion was significant for disease-specific survival rate (p0.0205). Venous invasion was the only independent prognostic factor in pathologically localized UUT-UC.
Keywords nephroureterectomy transitional cell carcinoma upper urinary tract
Amo Type Corrected and Republished Article
Publication Title Acta Medica Okayama
Published Date 2011-04
Volume volume65
Issue issue2
Publisher Okayama University Medical School
Start Page 143
End Page 149
ISSN 0386-300X
NCID AA00508441
Content Type Journal Article
language English
Copyright Holders CopyrightⒸ 2011 by Okayama University Medical School
File Version publisher
Refereed True
PubMed ID 20200581
Web of Science KeyUT 000289818800011
JaLCDOI 10.18926/AMO/45273
FullText URL 65_2_135.pdf
Author Matsuo, Toshihiko| Himei, Kengo| Ishii, Keita| Ichimura, Kouichi| Yanai, Hiroyuki| Nose, Soichiro| Mimura, Tetsushige|
Abstract An 18-year-old woman with a 2-year history of hypertension and headache was diagnosed with noradrenalin-secreting bilateral adrenal pheochromocytomas with paragangliomas in the background of von Hippel-Lindau disease with family histories and a missense mutation, 712C to T (Arg167Trp) in the VHL gene. She had optic disc hemangioma in the left eye which gradually enlarged and caused serous retinal detachment on the macula in one year. Low-dose external beam radiation (20 Gy) was administered to the left eye using a lens-sparing single lateral technique. She underwent craniotomy for cerebellar hemangioblastoma at the age of 22 years and total pancreatectomy for multiple neuroendocrine tumors at the age of 24 years. In the 6-year follow-up period after the radiotherapy, the optic disc hemangioma gradually reduced in size and its activity remained low, allowing good central vision to be maintained. External beam radiation is recommended as a treatment option for the initial therapy for optic disc hemangioma.
Keywords retinal (papillary, optic disc) hemangioma von Hippel-Lindau disease pheochromocytoma pancreatic neuroendocrine tumor external beam radiation (radiotherapy)
Amo Type Case Report
Publication Title Acta Medica Okayama
Published Date 2011-04
Volume volume65
Issue issue2
Publisher Okayama University Medical School
Start Page 135
End Page 141
ISSN 0386-300X
NCID AA00508441
Content Type Journal Article
language English
Copyright Holders CopyrightⒸ 2011 by Okayama University Medical School
File Version publisher
Refereed True
PubMed ID 21519372
Web of Science KeyUT 000289818800010
JaLCDOI 10.18926/AMO/45272
FullText URL 65_2_129.pdf
Author Toyota, Noriko| Ogawa, Daisuke| Ishii, Keita| Hirata, Kyoji| Wada, Jun| Shikata, Kenichi| Makino, Hirofumi|
Abstract A 62-year-old woman with a history of poorly controlled type 2 diabetes mellitus was admitted to our hospital with a 3-week history of mild fever, vomiting, and anorexia. Abdominal computed tomography (CT) showed bilateral hydronephrosis and gas accumulation in the urinary bladder wall and left ureter. Laboratory tests showed leukocytosis and elevated C-reactive protein level. Urine culture showed heavy growth of Escherichia coli. The final diagnosis was emphysematous cystitis. The patient was treated with systemic antibiotics and drainage using a urethral catheter. The clinical and radiographic findings resolved rapidly, and she was discharged from the hospital on day 28. Emphysematous cystitis is a relatively rare urinary tract infection associated with gas formation, and has the potential for a serious outcome if untreated. Early detection by imaging studies such as CT is important in providing prompt treatment and favorable clinical outcome.
Keywords computed tomography diabetes mellitus emphysematous cystitis
Amo Type Case Report
Publication Title Acta Medica Okayama
Published Date 2011-04
Volume volume65
Issue issue2
Publisher Okayama University Medical School
Start Page 129
End Page 133
ISSN 0386-300X
NCID AA00508441
Content Type Journal Article
language English
Copyright Holders CopyrightⒸ 2011 by Okayama University Medical School
File Version publisher
Refereed True
PubMed ID 21519371
Web of Science KeyUT 000289818800009
JaLCDOI 10.18926/AMO/45270
FullText URL 65_2_113.pdf
Author Morikawa, Toshio| Yamamoto, Yuji| Miyaishi, Satoru|
Abstract We have developed a new method for sex determination based on simultaneous detection of the SRY (sex-determining region Y), STS (steroid sulfatase) and amelogenin (AMELX and AMELY) gene regions and their homologous sequences. The sex of 246 blood samples was correctly determined by this method. An AMELY-deleted male sample, which would have been erroneously considered female based solely on analysis of the amelogenin locus, was successfully identified as male by the present method. The detection limit of this method was 63 pg of genomic DNA, and the male DNA component could be detected from mixed samples having a male:female ratio as low as 1:10. This method was useful for degraded DNA and possessed the human specificity. Practical application to 35 autopsy cases is described.
Keywords sex determination SRY (sex-determining region Y) multiplex PCR forensic casework
Amo Type Original Article
Publication Title Acta Medica Okayama
Published Date 2011-04
Volume volume65
Issue issue2
Publisher Okayama University Medical School
Start Page 113
End Page 122
ISSN 0386-300X
NCID AA00508441
Content Type Journal Article
language English
Copyright Holders CopyrightⒸ 2011 by Okayama University Medical School
File Version publisher
Refereed True
PubMed ID 21519369
Web of Science KeyUT 000289818800007
JaLCDOI 10.18926/AMO/45269
FullText URL 65_2_105.pdf
Author Tsuzuki, Takao| Okada, Hiroyuki| Nasu, Junichiro| Takenaka, Ryuta| Inoue, Masafumi| Kawano, Seiji| Kita, Masahide| Hori, Keisuke| Yamamoto, Kazuhide|
Abstract The objectives of this study were to evaluate the accuracy of endoscopic ultrasonography (EUS) in local and regional staging of early gastric cancer, to analyze the factors influencing the accuracy of EUS, and to reveal the usefulness and problems of EUS in pre-treatment staging of gastric cancer. We examined 105 lesions in 104 patients with histologically confirmed gastric cancer and retrospectively evaluated them with EUS. The diagnostic accuracy, sensitivity, and specificity of EUS were determined by comparing the pre-treatment EUS with the postoperative histopathological findings. The overall diagnostic accuracy of EUS for the depth of cancer invasion was 86%. The overall sensitivity and specificity were 60% and 96%, respectively. The accuracy significantly declined in lesions located in the upper-third of the stomach (70%). Type 0-I lesions tended to be over-staged (12&), and the upper-third lesions tended to be under-staged (23%). The accuracy significantly declined in differentiated adenocarcinoma with massive submucosal invasion (56.5%). EUS is useful for evaluating the depth of gastric cancer invasion which determines the feasibility of endoscopic treatment. However, it is noteworthy that the diagnostic accuracy of the invasion depth diminished for lesions in the upper third of the stomach.
Keywords endoscopic ultrasonography early gastric cancer accuracy sensitivity specificity
Amo Type Original Article
Publication Title Acta Medica Okayama
Published Date 2011-04
Volume volume65
Issue issue2
Publisher Okayama University Medical School
Start Page 105
End Page 112
ISSN 0386-300X
NCID AA00508441
Content Type Journal Article
language English
Copyright Holders CopyrightⒸ 2011 by Okayama University Medical School
File Version publisher
Refereed True
PubMed ID 21519368
Web of Science KeyUT 000289818800006
JaLCDOI 10.18926/AMO/45266
FullText URL 65_2_81.pdf
Author Sasaki, Motofumi| Shikata, Kenichi| Okada, Shinichi| Miyamoto, Satoshi| Nishishita, Shingo| Usui Kataoka, Hitomi| Sato, Chikage| Wada, Jun| Ogawa, Daisuke| Makino, Hirofumi|
Abstract Glomerular hyperfiltration is a common pathway leading to glomerulosclerosis in various kinds of kidney diseases. The 5/6 renal ablation is an established experimental animal model for glomerular hyperfiltration. On the other hand, low-grade inflammation is also a common mechanism for the progression of kidney diseases including diabetic nephropathy and atherosclerosis. Here we analyzed the gene expression profile in the remnant kidney tissues of 5/6 nephrectomized mice using a DNA microarray system and compared it with that of sham-operated control mice. The 5/6 nephrectomized mice showed glomerular hypertrophy and an increase in the extracellular matrix in the glomeruli. DNA microarray analysis indicated the up-regulated expression of various kinds of genes related to the inflammatory process in remnant kidneys. We confirmed the up-regulated expression of platelet factor-4, and monocyte chemoattractant protein-1, 2, and 5 in remnant kidneys by RT-PCR. The current results suggest that the inflammatory process is involved in the progression of glomerulosclerosis and is a common pathway of the pathogenesis of kidney disease.
Keywords kidney inflammation chemokine
Amo Type Original Article
Publication Title Acta Medica Okayama
Published Date 2011-04
Volume volume65
Issue issue2
Publisher Okayama University Medical School
Start Page 81
End Page 89
ISSN 0386-300X
NCID AA00508441
Content Type Journal Article
language English
Copyright Holders CopyrightⒸ 2011 by Okayama University Medical School
File Version publisher
Refereed True
PubMed ID 21519365
Web of Science KeyUT 000289818800003
Author Mori, Nobutane|
Published Date 1935-04-30
Publication Title 岡山医学会雑誌
Volume volume47
Issue issue4
Content Type Journal Article
Author Kochi, Takeshi|
Published Date 1935-04-30
Publication Title 岡山医学会雑誌
Volume volume47
Issue issue4
Content Type Journal Article
Author Watanabe, Takeshi|
Published Date 1935-03-31
Publication Title 岡山医学会雑誌
Volume volume47
Issue issue3
Content Type Journal Article
Author Wada, Masayuki|
Published Date 1937-10-31
Publication Title 岡山医学会雑誌
Volume volume49
Issue issue10
Content Type Journal Article
Author Miki, Yukiharu|
Published Date 1937-07-31
Publication Title 岡山医学会雑誌
Volume volume49
Issue issue7
Content Type Journal Article